ライフサイエンスコーパス: carrier

1 ith variant status known (59 carriers/70 non-carriers).

2 A total of 49.2% was identified as carrier.

3 or to its packaging into a nascent transport carrier.

4 ic interactions with the alkyl chains of the carrier.

5 lin, and piperacillin, using histone H1 as a carrier.

6 ge excess of non-radioactive tracer known as carrier.

7 bility and tensile strength of the OSA-based carrier.

8 of this mutation in a compound heterozygous carrier.

9 nsepidermal water loss (TEWL) in risk allele carriers.

10 benefit from PARPi beyond gBRCA1/2 mutation carriers.

11 ylaxis with ertapenem reduces SSI risk among carriers.

12 thogenic variants was similar to that of non-carriers.

13 nts on the development of biocompatible gene carriers.

14 ntrathecal environment in HTT gene expansion carriers.

15 es garnered benefits, with reductions in new carriers.

16 of transmission of the virus by asymptomatic carriers.

17 CI, 4.4 months to NA) for sBRCA1/2 mutation carriers.

18 ior to estimated onset of MCI among mutation carriers.

19 versus taxanes to treat advanced BC in BRCA carriers.

20 ,994 participants, 19.30% were APOE epsilon4 carriers.

21 est plasma levels of MIF than other genotype carriers.

22 to diverge between mutation carriers and non-carriers.

23 well-curated clinical cohort of PTEN-variant carriers.

24 CGC, while no difference was seen in CGC/TTT carriers.

25 duce mid-gap states that rapidly trap charge carriers.

26 r risk management in pathogenic CDH1 variant carriers.

27 et might be of benefit in HTT gene expansion carriers.

28 lished two independent colonies of transgene carriers.

29 d symptoms relative to familial mutation non-carriers.

30 ult of interactions of native bioactives and carriers.

31 3 were moderate drinkers and 90 were ADH1B*2 carriers.

32 Mitochondrial pyruvate carrier 1 (MPC-1) appears to be a tumor suppressor.

33 ildren (age 8-12 years, 19/14 male/female PM carriers, 15/13 male/female controls).

34 lates collected through surveys from healthy carriers 2 years from 13-valent PCV (PCV13) introduction

35 re was a 9.1% relative reduction in incident carriers (20.4% and 1.6% in participating and nonpartici

36 f these, 66 (10.1%) subjects were incidental carriers, 22 (3.3%) were short-term carriers, and 38 (5.

37 to ASD and psychosis in 106 22q11.2 deletion carriers, 38 22q11.2 duplication carriers, and 82 demogr

38 PD, 40 LRRK2-PD, 70 GBA-PD, 196 healthy non-carriers, 55 LRRK2-NMC and 97 GBA-NMC participated in th

39 status and 129 with variant status known (59 carriers/70 non-carriers).

40 magnetic resonance imaging data from 101 CNV carriers, 755 individuals with idiopathic ASD, SZ, or AD

41 is of 9099 genes with sufficient LOF variant carriers, a significant association between AF and rare

42 geted carnosine polymersomes, LRP-1-targeted carriers accumulated in brain in a time dependent manner

43 in left parahippocampus indicated that in e4 carriers activity did not differentiate subsequently rem

44 were significantly elevated in APOE epsilon4 carrier AD patients.

45 The role of hapten-carrier adducts in re-challenge reactions leading to mas

46 cantly increased in symptomatic GRN mutation carriers (adjusted mean difference from controls 192.3 p

47 vival in the hysteresis zone for effloresced carrier aerosols was confirmed.

48 yte production in asymptomatic P. falciparum carriers allowing early detection and treatment of infec

49 Germany, UK, and USA identified five variant carriers among AD patients only.

50 When compared with carriers among controls, pneumococcal absolute abundance

51 n for liver cancer using the radiopaque drug-carrier and micro-embolic agent Lipiodol, which has been

52 First, we define the single-carrier and multicarrier mechanisms for axis-dependent c

53 ine hundred and fifty-nine of which included carrier and non-carriers of the APOE epsilon4 gene, thos

54 To investigate this, 10 HNF1A mutation carriers and 10 control subjects without diabetes were r

55 tes deep within the bandgap that trap charge carriers and cause them to recombine non-radiatively.

56 trols, or any of the presymptomatic mutation carriers and controls.

57 ifestations of COVID-19 include asymptomatic carriers and fulminant disease characterized by sepsis a

58 nergy-dependent mean free path of the charge carriers and is affected by crystal structure, scatterin

59 is apparent in cognitively unimpaired APOE4 carriers and more severe in those with cognitive impairm

60 bility of plasma NfL to discriminate between carriers and non-carriers only reached high sensitivity

61 entrations begin to diverge between mutation carriers and non-carriers.

62 eta accumulation is greater in APOE epsilon4 carriers and older individuals.

63 ject engineered ultrasound-controllable drug carriers and subsequently apply a novel two-component Ag

64 es with a high fraction of long-lived charge carriers and the availability of a reductive and an oxid

65 ore than 2600 years but the nature of charge carriers and their transfer mechanisms still remain poor

66 odate a variety of guest molecules as proton carriers and to systemically regulate the proton concent

67 n PALB2 (242-fold enrichment in Finland, 336 carriers) and an average PRS (10-90(th) percentile) have

68 er-reduction midpoint potential (E degrees ) carrier, and the other to the higher-E degrees electron

69 cidental carriers, 22 (3.3%) were short-term carriers, and 38 (5.8%) were long-term carriers; the rem

70 .2 deletion carriers, 38 22q11.2 duplication carriers, and 82 demographically matched healthy control

71 Our goal was to determine whether CF carriers are at increased risk for a range of CF-related

72 However, 8% of female carriers are symptomatic and underrepresented in researc

73 t photothermal processes, in contrast to hot carriers, are the main contributor to the observed chang

74 AS, as clinical assessment fails to identify carriers at risk before significant neurological symptom

75 Here, ultralow bandgap GNRs with charge carriers behaving as massive Dirac fermions can be reali

76 that distinguishes nanoscale and macroscale carrier behaviors.

77 These MOF carriers can also serve as the disintegrating agents to

78 Among rs1333049 risk-allele carriers (CC+GC), the incidence of MI was reduced in the

79 Population-based using 2010-2019 Medicare carrier claims.

80 wnstream product, the mitochondrial electron carrier coenzyme Q, both in cultured cancer cells and tu

81 and surface area in C9orf72 expansion adult carriers compared to healthy controls to characterize pr

82 e significantly greater among PSEN1 mutation carriers, compared with noncarriers, from approximately

83 surement of work function, sheet resistance, carrier concentration and mobility in both macro-, micro

84 way to control the local electric field and carrier concentration in van der Waals heterostructures

85 Conventionally, the carrier concentration is used as the reflection of the F

86 Moreover, by tuning the top TSS carrier concentration, a competition between the top and

87 le of chemical doping lies in optimizing the carrier concentration, but there can potentially be othe

88 f magnitude, which is the result of elevated carrier concentrations.

89 in, PolyRad alone without melatonin (PolyRad carrier control), non-radiated PolyRad, and irradiated P

90 < 200 cells/muL outcome for deletion allele carriers (Cox regression analysis: hazard ratio, 2.4 [95

91 roscopy is used to explore the nature of the carriers created following doping of conjugated push-pul

92 was to evaluate whether preclinical mutation carriers demonstrate unique FTD-related symptoms relativ

93 f >8% because domains can afford much higher carrier densities.

94 bled vacancy concentration raises the charge carrier density and suppresses bipolar diffusion, result

95 n-type and p-type doping) and realizing high carrier density while maintaining good mobility have bee

96 y broken type-III gap, thus offering optimal carrier density without any gate voltages, in true-equil

97 n a large structural expansion and increased carrier density, leading to an exotic ferromagnetic to p

98 complexes to Golgi--derived quality control carriers destined for lysosomes.

99 he new HTL enables a 1.4x increase in charge carrier diffusion length in the active layer; and as a r

100 HD gene carriers display regional variability in the spatial pat

101 n the surface massive Dirac band is slightly carrier doped by a gate voltage, the edge state starts t

102 meability that limit the applicability of O2 carriers during infusion.

103 uence on vibrational, optical properties and carrier dynamics are investigated.

104 stacking-order driven optical properties and carrier dynamics of ReS(2) , mediate many seemingly cont

105 he dimensionality, as a hidden constraint on carrier dynamics, and identify the diffusion length as a

106 than half of HCC patients being chronic HBV carriers, even if underlying mechanisms of tumorigenesis

107 Preclinical mutation carriers exhibited neuropsychiatric symptoms compared wi

108 alignment and concerted cascade interfacial carrier extraction, rendered by concurrent positioning o

109 The solute carrier family 13 (slc13) transporters mediate transport

110 chondrial fusion-fission-related gene solute carrier family 25 member 46 (Slc25a46) and treated them

111 We studied the functions of the solute carrier family 39 member 4 (SLC39A4, also called ZIP4),

112 Pathogenic mutations in the solute carrier family 7 member 5 (SLC7A5) gene, which encodes a

113 ed numerous variants of the endosomal solute carrier family 9 member A6 (SLC9A6)/(Na(+),K(+))/H(+) ex

114 e-phase droplets (aqueous plugs segmented by carrier fluid), with limits of detection down to 7 nM (3

115 g is segmented from the others by immiscible carrier fluid.

116 based on Newtonian and neutral viscoelastic carrier fluids.

117 Specific deuteration furnishes a "stealth" carrier for the solubilized IMP.

118 mis coated with peptoid (PE2) can be used as carriers for anticancer drug and protein, where the pept

119 Up to 37% of individuals may be heterozygous carriers for at least one dominant atopy risk mutation.

120 d considerable interest as fast ionic charge carriers for electrochemical energy storage.

121 f advanced delivery systems as sophisticated carriers for therapeutic agents.

122 h rhBMP-2/ACS, acting as suitable and viable carriers for vertical bone augmentation.

123 tons of dissimilar amplitudes, durations and carrier frequencies.

124 Increasing the proportion of detected carriers from 1 in 9 up to 1 in 5 yielded linear reducti

125 roups (p<0.0001), and began to differentiate carriers from non-carriers when aged 22 years (22 years

126 r(4) act as the charge storage element where carriers from the channel are injected, stored, or extra

127 Separately, we studied 117 mutation carriers from the DIAN (Dominant Inherited Alzheimer Net

128 e the internal volume, (3) the use of helium carrier gas to minimize nonideal mixture behavior, and (

129 tunable at a molecular level for high charge carrier generation and transfer.

130 However, metals that offer both hot-carrier generation in the near-infrared and sufficient c

131 hat noble-transition alloys can excel at hot-carrier generation reveals a new material platform for n

132 In BRCA1/2 mutation carriers, genetically proxied HMG-CoA reductase inhibiti

133 viduals with a CC genotype, and heterozygous carriers had intermediate expression.

134 controls, both LRRK2 and GBA non-manifesting carriers had significantly increased mean scores on the

135 In addition, CC genotype carriers had the highest plasma levels of MIF than other

136 nt for 3% of hypertrophic cardiomyopathy and carriers have a heterogeneous phenotype, with increased

137 Our findings suggest that these novel carriers have the ability to deliver neuroprotective car

138 Administration of hemoglobin-based oxygen carriers (HBOCs) into the systemic circulation is a pote

139 ory chains, whereas UQ is the major electron carrier in the reduction of dioxygen.

140 roaches for novel emerging radionuclides and carriers in development.

141 ad comparable sensitivity for identifying LS carriers in high-risk (89.3% v 85.7%; P = .712) and onco

142 The incidence of germline mutation carriers in the general population or in various clinica

143 ctrum of Parkinson's disease-associated gene carriers in this mainland Chinese population was similar

144 Charge carriers in two-dimensional transition metal dichalcogen

145 Using RNA nanoparticles as carriers increases the water-solubility of paclitaxel by

146 to increased scattering time for free charge carriers, indicating that scattering mechanisms limiting

147 ms associated with these processes relies on carrier injection.

148 Charge carrier insertion into the graphene makes the EEVD 10 ti

149 models are not a definitive descriptor of O2 carrier interaction in tumor capillary networks, we acco

150 models of delay propagation, we divided all carriers into two groups exhibiting a shifted power law

151 of TLR7 and RIG-I pathways using particulate carriers is a potential approach to improve cellular imm

152 centration and release rate from approved CS carriers is difficult to control with precision.

153 e that the critical process for photoexcited carriers is the escape of holes from trap states, which

154 mitochondrial ISCU (ISCU2) and the secondary carrier, ISCA1, as the direct donors of Fe-S clusters to

155 DJP(n=2) has a much longer carrier lifetime and absorption edge (580 nm, 2.13 eV) i

156 Their remarkable mobility and long carrier lifetime are also valuable for information techn

157 iting a narrow bandgap of 1.27 eV and a long carrier lifetime of 657.7 ns.

158 conds to the seconds, reveal that the charge carrier lifetimes as well as the charge injection and ch

159 neration in the near-infrared and sufficient carrier lifetimes remain elusive.

160 It is one of the most prevalent carrier lineages but also frequently causes severe invas

161 and cryopreserved from a lone, fertile, CHS carrier male.

162 tients without molecular diagnoses (i.e. non-carriers, median 46.0 years).

163 The model revealed that carrier-mediated transport alone cannot explain the expe

164 Furthermore, K. pneumoniae carrier mice were able to transmit to uninfected cohabit

165 Importantly, only carrier mice with dystrophic mothers showed mortality af

166 Transient absorption spectra reveal the carrier migration from low n to high n species with diff

167 ies of the fabricated devices such as charge carrier mobility (u), barrier height ( (b)), series resi

168 aded electronic bandgap, which increases the carrier mobility and impedes carrier recombination.

169 The high hole carrier mobility is uncommon for complex bulk materials

170 The electrical conductivity and carrier mobility of single crystals exhibit a metallic b

171 ing a significant enhancement (4.7 times) of carrier mobility.

172 In this work, a dystrophinopathy carrier mouse model was derived by breeding male or fema

173 e MPC2 subunit of the mitochondrial pyruvate carrier (MPC) is presented.

174 d prediabetes were more frequent among LRRK2 carriers, MS does not seem to influence GBA and LRRK2-PD

175 Participants included symptomatic carriers (n=185) of a pathogenic mutation in chromosome

176 not among the other 2 phenotypes (Hp1 allele carriers) (n = 3,673; aHR: 0.95; 95% CI: 0.79 to 1.13; p

177 Carrier-NAAT patients had positive stool NAAT but no dia

178 currently unknown if and when an individual carrier of a premutation allele will develop FXTAS, as c

179 ine triacetic acid (EDT) were developed as a carrier of DOX for GBM chemotherapy.

180 a consequence, the use of B-form DNA as the carrier of genetic information must have co-evolved with

181 hat RNA was the first replicable information carrier of the prebiotic era-that is, prior to the dawn

182 Among carriers of a monogenic risk variant, we estimate substa

183 spinon excitations behave like the fermionic carriers of a paramagnetic metal.

184 cluded 106 presymptomatic and 54 symptomatic carriers of a pathogenic mutation in GRN, C9orf72 or MAP

185 A negative association between PFS and carriers of any A at NLRP1 rs12150220 and AA for SRL rs1

186 perienced improved survival in comparison to carriers of APOE2.

187 otype in our first 100 genetically confirmed carriers of biallelic repeat expansions in RFC1 and iden

188 Homozygous carriers of both iRBD-specific SNPs were at highly incre

189 Carriers of CGC/CGT and TTT/TTT had 35% higher apparent

190 ce over a wide range using different dietary carriers of DHA, and the correlations between the increa

191 ere either heterozygous or homozygous (n=47) carriers of factor V Leiden.

192 pene lactones may be considered as potential carriers of food functionality.

193 s evidenced by cancer predisposition in both carriers of germline loss-of-function mutations and gene

194 with inherited bleeding disorders, including carriers of hemophilia A and B, or with von Willebrand d

195 Carriers of large recurrent copy number variants (CNVs)

196 TIPE proteins are carriers of lipid second messengers.

197 nd the PREMM(5) prediction model to identify carriers of LS and non-LS pathogenic variants (PVs) amon

198 In addition, we calculated that unaffected carriers of mutations are numerous, ranging from 1 in 2.

199 hrocytes (red blood cells [RBCs]) as passive carriers of oxygen to recognizing the complex interplay

200 we characterize the penetrance of cancer in carriers of pathogenic BRCA1 and BRCA2 variants.

201 Four homozygous carriers of pathogenic NPC1 mutations were also identifi

202 fifty-nine of which included carrier and non-carriers of the APOE epsilon4 gene, those at highest ris

203 her, brother and one aunt were identified as carriers of the familial CDH1 mutation and subsequently

204 chronically increased contact activation in carriers of the FXII-W268R variant.

205 alysis investigating the age at first SCD in carriers of the mutation.

206 In a dominant model, carriers of the rs2069705T allele compared with the rs20

207 mptomatic, asymptomatic, and pre-symptomatic carriers of the virus.

208 Carriers of this FOLH1 variant had less efficient cortic

209 harmaceuticals based on low-molecular-weight carriers offer many clinically advantageous attributes r

210 NfL to discriminate between carriers and non-carriers only reached high sensitivity close to the age

211 In a direct follow-up survey with all carriers, only 25.2% of individuals reported a family hi

212 he cytoplasm by hitchhiking on motor-driven "carrier" organelles.

213 , so did the corresponding relative odds for carriers (P < 0.001).

214 e RF radiation for periods comparable to the carrier-pair lifetime.

215 ncing in one affected dog and its obligatory carrier parents identified a 1 bp insertion (CFA20:g.33,

216 affected individuals and their asymptomatic carrier parents, reduced SW-AF intensities, measured as

217 in GRN, C9orf72 or MAPT, and 70 healthy non-carriers participating in the Genetic Frontotemporal dem

218 -Makona strain (EBOV/Mak) on stainless-steel carriers per ASTM E2197-11.

219 global metabolomic profiling of premutation carriers (PM) who, as part of an ongoing longitudinal st

220 CSA reduction was also faster in mutation carriers predominantly in the ventrofrontal regions.

221 adult premanifest Huntington's disease gene carriers (preHD) far from predicted clinical symptom ons

222 Acyl carrier protein (ACP) is a highly conserved cofactor pro

223 ich BioZ proteins catalyze a 3-ketoacyl-acyl carrier protein (ACP) synthase III-like reaction to prod

224 Cyanobacteria possess two enzymes, acyl-acyl carrier protein (acyl-ACP) reductase (AAR) and aldehyde-

225 ase (CT)-alpha, CT-beta, and biotin carboxyl carrier protein (BCCP1 or BCCP2).

226 The enoyl-acyl carrier protein reductase enzyme FabI is essential for f

227 tation p.L81R and pR212W in malonyl CoA-acyl carrier protein transacylase (MCAT), a mitochondrial pro

228 preferred acyl donors, while acyl-ACP (acyl carrier protein), free fatty acids, or galactolipid-boun

229 nes (putatively encoding beta-ketoacyl-(acyl-carrier-protein) synthases, peroxisomal acyl-activating

230 selects from the bacterial pool of acyl-acyl carrier proteins (ACPs) an acyl chain of a specific leng

231 acterization of two late-acting Fe-S cluster-carrier proteins from Arabidopsis thaliana, NFU4 and NFU

232 chondrial presequence-containing but not for carrier proteins.

233 f novel fentanyl-based haptens conjugated to carrier proteins.

234 We demonstrate that an increase in carrier proteome level requires a concomitant increase i

235 In asymptomatic carriers, qAF disclosed previously undetected visual cyc

236 eading to improved charge transport, reduced carrier recombination, and a high power conversion effic

237 h increases the carrier mobility and impedes carrier recombination.

238 , which are of significance to influence the carriers recombination and hysteresis in perovskite sola

239 nosis, and treatment for a broad range of CF carrier-related conditions.

240 mutations and from asymptomatic heterozygous carriers released heightened IL-1beta specifically in re

241 age of 1.8 reportable variants per child for carrier results.

242 Furthermore, it is possible to establish a carrier scattering phase diagram, which can be used to s

243 poses a key barrier to the broad utility of carrier screening.

244 Thus, we suggest that mid-age e4 carriers show a breakdown of normal MTL activation and s

245 classical monocyte subset of DNMT3A mutation carriers showed increased expression of T-cell stimulati

246 brain tissue from two CYLD p.M719V mutation carriers showed widespread glial CYLD immunoreactivity.

247 A plasma membrane transporter, the solute carrier (SLC) human multidrug and toxin extrusion protei

248 tic heterogeneity, dosage effect, unaffected carrier status, and incomplete penetrance.

249 ction of non-safe microcapsule dose leads to carriers staying in glomeruli for at least 48 h which ha

250 table, biocompatible and cost-effective drug carrier system with high encapsulation efficiency.

251 on of biologically active proteins on a gold carrier technique with the ability to detect viral or ba

252 t iPSC-derived iNeurons from a MAPT mutation carrier tend to be more sensitive to cell death induced

253 se challenges signify an unmet need for drug carriers that can cross the BBB and deliver drugs to tar

254 TGN) has been shown to occur through tubular carriers that emanate from the TGN or through vesicular

255 neuropsychiatric symptoms compared with non-carriers that may be considered as future clinical trial

256 at emanate from the TGN or through vesicular carriers that recruit GGA (Golgi-localized, gamma-ear-co

257 s are connected by small diffusible electron carriers, the mobility of which is challenged by macromo

258 -term carriers, and 38 (5.8%) were long-term carriers; the remaining 530 (80.8%) were noncarriers.

259 oth the "smart zipper lock" and the delivery carrier to alternately lock multiple functional DNAs thr

260 ses the use of CaCO(3) crystals as versatile carriers to host, protect and release antimicrobials, of

261 The transfer of WTA from lipid carriers to PG, catalyzed by the LytR-CpsA-Psr (LCP) enz

262 nted side effects; thus, the ability of such carriers to target their cargo to cancer cells is crucia

263 highlighted the importance of various solute carriers to the toxicity of anticancer drugs, the contri

264 (Saccharomyces cerevisiae), EVs function as carriers to transport cargo proteins into the periplasm

265 to regular grain boundaries which block the carrier transport and behave as the non-radiative recomb

266 gle-crystal hybrid perovskites show improved carrier transport and enhanced stability over their poly

267 Yet, the ultrafast carrier transport in mid-infrared QCLs has so far consti

268 ion and recombination in the time domain and carrier transport in the spatial domain.

269 n of the OSC layer, enabling optimization of carrier transport.

270 that phonon scattering dominates the charge carrier transport.

271 ighly interconnected conducting channels for carrier transport.

272 le rates of postnatal survival and growth to carrier-treated controls.

273 is found to be ambipolar, with its dominant carrier type dramatically affected by the environment.

274 tent inhibitor of the mitochondrial pyruvate carrier (UK5099) decreased the NADH/NAD(+) ratio and red

275 e generated a symptomatic mouse model of DMD carriers via injection of mdx (murine DMD) embryonic ste

276 In HNF1A mutation carriers, we observed: 1) hypoinsulinemia, 2) insulinotr

277 The developed carriers were also able to deliver RNPs to restore dystr

278 Additionally, G-carriers were more sensitive to physical pain.

279 altered pain perception in C9orf72 expansion carriers were the bilateral thalamus and striatum as wel

280 .8% vs. 4.4%) and C allele (20.4% vs. 23.9%) carriers were the lowest.

281 Overexpressing WFhb1-1 in non-Qfhb1-carrier wheat led to a significant decrease (p < 0.01) i

282 ed kernels, while silencing WFhb1-1 in Qfhb1-carrier wheat resulted in a significant increase (p < 0.

283 and began to differentiate carriers from non-carriers when aged 22 years (22 years before the estimat

284 NK1 was significantly lower than that of non-carriers, while the age at onset of carriers with other

285 n ATL than did high-risk, age-matched HTLV-1 carriers who remained ATL-free after a median of 10 year

286 screening in patients could identify at-risk carriers, who would not be otherwise identified in routi

287 unknown when, and if, individual premutation carriers will develop FXTAS.

288 y all genes (more than 97%) had at least one carrier with a LOF variant, and most genes (more than 69

289 and inherited thrombophilia (factor V Leiden carriers with a 10-year cumulative incidence of 10.9%),

290 most genes (more than 69%) had at least ten carriers with a LOF variant.

291 ticles (YCWPs) were used as model cell-based carriers with distinct intracellular composition and cur

292 T imaging characteristics in non-manifesting carriers with GBA and LRRK2 mutations compared with heal

293 trospectively analyzed 77 noncirrhotic HBsAg carriers with hematological cancer who received rituxima

294 Nineteen were asymptomatic carriers with low or high pVL; 19 were diagnosed with HA

295 be the scope of clinical phenotype in female carriers with mutations in RPGR and quantify the contrib

296 t of non-carriers, while the age at onset of carriers with other gene pathogenic/likely pathogenic va

297 These carriers, with their priorly incorporated functions, res

298 imed to investigate this symptom in mutation carriers within the Genetic FTD Initiative (GENFI).

299 iatal [(18) F]-fluorodopa uptake in mutation carriers without parkinsonism did not significantly diff

300 othesis that IL-6 pathway antagonism in CHIP carriers would decrease cardiovascular disease (CVD) ris