ライフサイエンスコーパス: cartilage repair

1 25 million MSCs was found to achieve optimal cartilage repair.

2 nhanced differentiation capacity for bone or cartilage repair.

3 critical properties that significant impact cartilage repair.

4 d more effective delivery systems to promote cartilage repair.

5 ) perivascular population, and contribute to cartilage repair.

6 reases contribution of Gdf5-lineage cells to cartilage repair.

7 rphologic assessment of the knee joint after cartilage repair.

8 se PHD-2 may represent a relevant target for cartilage repair.

9 esting their potential utility for articular cartilage repair.

10 an chondrocyte function and a new target for cartilage repair.

11 ential in engineered cartilage formation and cartilage repair.

12 n the nanoscale for application to articular cartilage repair.

13 nce in formulating effective stem cell-based cartilage repair.

14 iation and of cell replacement therapies for cartilage repair.

15 e application of growth factors to articular cartilage repair.

16 tor involved in chondrogenesis and articular cartilage repair.

17 s in vitro and in vivo and enhance articular cartilage repair.

18 practical utility for tissue engineering and cartilage repair.

19 rtilage lubrication, can inhibit integrative cartilage repair.

20 CPII, both of which are putative markers of cartilage repair.

21 ns reduced inflammation and greatly improved cartilage repair.

22 itate finding an alternative cell source for cartilage repair.

23 io), thus showing superior potential towards cartilage repair.

24 fibrosis, inflammation, chondrogenesis, and cartilage repair.

25 leads to subchondral bone defects and limits cartilage repair after MASI.

26 therapeutic solution for targeted articular cartilage repair, allowing for a controlled and minimall

27 (MSCs) provide an attractive cell source for cartilage repair and cell therapy; however, the underlyi

28 ntiation into chondrocytes led to successful cartilage repair and chondrocyte rejuvenation.

29 elf-assembling peptide hydrogel scaffold for cartilage repair and developed a method to encapsulate c

30 cost-effective GAG manipulation approach to cartilage repair and joint preservation, offering insigh

31 a unique model for adult chondrogenesis and cartilage repair and may serve as inspiration for novel

32 development of next-generation therapies for cartilage repair and OA prevention.

33 rm for developing therapeutic approaches for cartilage repair and osteoarthritis treatment.

34 o study genetic and environmental factors in cartilage repair and osteoarthritis.

35 of tissue-engineered products for articular cartilage repair and particularly cell-based therapies.

36 and result in a challenging environment for cartilage repair and regeneration.

37 itional MR imaging techniques for imaging of cartilage repair and their application to longitudinal s

38 critical properties involved in MSC-induced cartilage repair, and adapted for other clinical indicat

39 acts that may be relevant to osteoarthritis, cartilage repair, and inflammatory responses.

40 ulin-like growth factor 1 (IGF-1) stimulates cartilage repair but is not a practical therapy due to i

41 udy indicate that ACI is capable of not only cartilage repair but, in some cases, regeneration.

42 are an attractive allogeneic cell source for cartilage repair, but their clinical translation has bee

43 ro and improved the persistence of articular cartilage repair by preventing vascularization and bone

44 se effects of NO may result in impairment of cartilage repair, by interfering with the extracellular

45 l loss at 2 weeks correlated with incomplete cartilage repair, diagnosed at histopathologic examinati

46 ant issue affecting the use of stem cells in cartilage repair, especially with regard to the persiste

47 e entire limbs, digit tip regrowth and joint cartilage repair following joint distraction suggest lat

48 In order to improve cartilage repair, future studies need to elucidate the r

49 We investigated the effect of VEGF on cartilage repair in an immunodeficiency rat model of OA

50 ng-based treatment of osteoarthritis and for cartilage repair in animal models and clinical trials ar

51 ransplantation revealed significantly better cartilage repair in animals that received BMP-4-transduc

52 -invasive therapeutic modality for articular cartilage repair in future preclinical and clinical rese

53 have previously found that the capacity for cartilage repair in human adult articular chondrocytes i

54 brid biomimetic scaffold as a niche to favor cartilage repair in mechanically active joints using a c

55 Gdf5 expression was also upregulated during cartilage repair in mice and was switched on in injured

56 d mesenchymal stem cells (MSCs) and enhances cartilage repair in mouse osteoarthritis (OA) models.

57 ct against cartilage degradation and promote cartilage repair in OA.

58 dicate that N-TEC can directly contribute to cartilage repair in osteoarthritic joints.

59 Cartilage repair in osteoarthritic patients remains a ch

60 genesis and significantly improved articular cartilage repair in rats.

61 on of the recombinant GEP accelerates rabbit cartilage repair in vivo.

62 In particular, cartilage repair is important to avoid physical disabili

63 enge in choosing an appropriate scaffold for cartilage repair is the identification of a material tha

64 We evaluated cartilage repair macroscopically and histologically 4, 8

65 were correlated with quantitative scores for cartilage repair (MOCART score and ICRS score) at 12 wee

66 hage polarization contribute to the enhanced cartilage repair observed in MRL/MpJ mice.

67 lopment of tissue engineering approaches for cartilage repair or regeneration for the treatment of jo

68 The cartilage repair osteoarthritis knee score (CROAKS) opti

69 msec +/- 1.8; P < .001) and no difference in cartilage repair outcomes compared with unlabeled contro

70 Background Cartilage repair outcomes of matrix-associated stem cell

71 ascular injury in immature epiphyses affects cartilage repair outcomes of matrix-associated stem cell

72 This corresponded to poor cartilage repair outcomes of the apoptotic hMSC transpla

73 strated machine learning of patient-specific cartilage repair post MSC therapy.

74 successfully engineered tissues, but today, cartilage repair products are few and they exhibit consi

75 Bringing additional cartilage repair products to the market will require an

76 t now finally lead to the development of new cartilage repair products.

77 hat HA/RHAMM interactions play a key role in cartilage repair/regeneration via stimulating inflammato

78 Articular cartilage repair remains a significant and growing clini

79 enabled precise prediction of post-treatment cartilage repair scores with coefficient of determinatio

80 In vivo testing of articular cartilage repair showed that VEGF-transduced MDSCs cause

81 w-derived mesenchymal stem cells (BMMSC) for cartilage repair strategies after trauma.

82 the efficacy of pharmacologic treatments and cartilage repair strategies, but noninvasive techniques

83 t decade although more than 200 large animal cartilage repair studies were published.

84 f strategies and technologies for cell-based cartilage repair, such as the disconnect between univers

85 drocytes group achieved substantially better cartilage repair than the chondrocytes-alone group that

86 Injectable scaffolds for cartilage repair that integrate both bioactivity and suf

87 potential clinical applications; cell-based cartilage repair therapies require significant in vitro

88 potential application for the development of cartilage repair therapies.

89 Only one cartilage repair therapy classified as a "cellular and g

90 were assessed by using the MR observation of cartilage repair tissue (MOCART) score (scale, 0-100), t

91 MR observation of cartilage repair tissue is a well-established semiquanti

92 order to stimulate growth and maturation of cartilage repair tissue.

93 ical for advancing cell therapy products for cartilage repair to clinical use.

94 rformed a meta-analysis on MSC therapies for cartilage repair using machine learning.

95 gmented microfracture significantly improves cartilage repair with a collagen fiber orientation more