ライフサイエンスコーパス: casein kinase

1 C) has recently been identified as the Golgi casein kinase.

2 clear translocation of PER2 are regulated by casein kinase.

3 ity 20C (Fam20C), is the physiological Golgi casein kinase.

4 sucrose non-fermenting-related kinase 2, or casein kinases.

5 ubiquitylation were blocked by disruption of casein kinase 1 (CK1) activity, and mass spectrometry an

6 lation was reduced by specific inhibitors of casein kinase 1 (CK1) and casein kinase 2 (CK2) (10 muM

7 such as phosphorylation of clock proteins by casein kinase 1 (CK1) and glycogen synthase kinase 3 (GS

8 ligase complex upon dual phosphorylation by casein kinase 1 (CK1) and glycogen synthase kinase 3beta

9 n shown to interact with various isoforms of casein kinase 1 (CK1) and keratins and to mediate organi

10 under physiological conditions and identify Casein Kinase 1 (CK1) as an upstream effector that bidir

11 rylation and that both were inhibited by the casein kinase 1 (CK1) delta/epsilon inhibitor IC261.

12 dies to show that Ser-247 is a target of the casein kinase 1 (CK1) family of protein kinases.

13 Here, the casein kinase 1 (CK1) Hrr25 is shown to be an endocytic

14 Casein kinase 1 (CK1) isoforms epsilon and delta, key ci

15 y protein kinase A (PKA) sites and secondary casein kinase 1 (CK1) or glycogen synthase kinase 3 (GSK

16 protein kinase C (PKC) site Cx43(S368A), the casein kinase 1 (CK1) sites Cx43(S325A/328Y/330A), and t

17 Casein kinase 1 (CK1) was identified as the major kinase

18 at Ser680 promotes Ser683 phosphorylation by casein kinase 1 (CK1), and these phosphorylation events

19 Phosphorylation of the COPII coat by casein kinase 1 (CK1), Hrr25, contributes to the directi

20 elsr1, Prickle1, FZD3, FZD7, Dvl2, Dvl3, and casein kinase 1 (CK1)-epsilon are upregulated in B lymph

21 Casein kinase 1 (CK1)-mediated phosphorylation of Cx43 p

22 ent manner by the plasma membrane-associated casein kinase 1 (CK1).

23 er-174 and Ser-175 by the nuclear isoform of casein kinase 1 (CK1).

24 Two such regulators, casein kinase 1 (CKI) and F-box and leucine-rich repeat

25 Here, we show that the Casein Kinase 1 (CKI) family is required for Expanded ph

26 ts G2 mode by blocking Srs2 DNA helicase and Casein Kinase 1 (Hhp1).

27 We also show casein kinase 1 (Hrr25) is a key kinase that phosphoryla

28 Strikingly, loss of casein kinase 1 activity causes constitutive activation

29 protein stability of FOXO3A is regulated by Casein Kinase 1 alpha (CK1alpha) in an oncogenic RAS-spe

30 Casein kinase 1 alpha (CK1alpha) is a serine/threonine k

31 sense mutations of the CSNK1A1 gene encoding casein kinase 1 alpha (CK1alpha) occur in a subset of my

32 Here, we report that casein kinase 1 alpha (CK1alpha) phosphorylates Cdc25A o

33 We found that casein kinase 1 alpha (Csnk1a1), a serine-threonine kina

34 ung cancer (NSCLC) cell lines, we identified casein kinase 1 alpha (CSNK1A1, CK1alpha).

35 Our results describe a role for casein kinase 1 as a direct regulator of sterol homeosta

36 nstrated that Ser(568) was phosphorylated by casein kinase 1 both in vitro and in vivo.

37 Human casein kinase 1 delta (CK1delta) and epsilon (CK1epsilon

38 Casein kinase 1 delta (CK1delta) and its closest homolog

39 Inhibition of casein kinase 1 delta (CK1delta) blocks primary ciliogen

40 rane recruitment by Frizzled (FZD) and (iii) Casein kinase 1 e (CK1e) has a key regulatory function i

41 Casein kinase 1 epsilon (CK1epsilon) and its closest hom

42 requires both non-canonical Wnt5a ligand and casein kinase 1 epsilon (CK1varepsilon), and that this e

43 self-renewal, by inducing the expression of casein kinase 1 epsilon.

44 be our isolation and characterization of the casein kinase 1 family member Hhp2 as a novel regulator

45 We demonstrate that Casein kinase 1 family members, including isoforms of Ta

46 he Hedgehog pathway are redundant with other Casein kinase 1 family members.

47 Depletion of casein kinase 1 gamma (CSNK-1) in Caenorhabditis elegans

48 a multifaceted approach, we have found that casein kinase 1 gamma 1 (CK1gamma1) carries out this fun

49 We further evaluated whether D4476, a casein kinase 1 inhibitor, would exhibit selective antil

50 Inhibition of casein kinase 1 may also contribute to the antitumoral a

51 in 90 and glycogen synthase kinase 3 but not casein kinase 1 nor LATS in YAP-mediated TAZ loss.

52 depends on the ubiquitin ligase Rsp5 and the casein kinase 1 redundant pair Yck1/Yck2.

53 Deregulation of CK1 (casein kinase 1) activity can be involved in the develop

54 ing protein (IQGAP); and three NFAT kinases, casein kinase 1, glycogen synthase kinase 3, and dual sp

55 e sensitive to pharmacological inhibition of Casein kinase 1, suggesting the possibility of shared cl

56 Csnk1e, the gene encoding casein kinase 1-epsilon, has been implicated in sensitiv

57 involves SOD1-mediated stabilization of two casein kinase 1-gamma (CK1gamma) homologs, Yck1p and Yck

58 y for calcineurin and decreased affinity for casein kinase 1.

59 iotic division is coordinated by a conserved casein kinase 1.

60 ral putative phosphosite mutations abrogated casein kinase 1.2 activity on HSP90, only Ser(289) could

61 HSP90 is a substrate for casein kinase 1.2-catalysed phosphorylation in vitro.

62 In this study, we determined the role of casein kinase-1 (CK1) in regulating NMDAR activity in th

63 Arsenite also recruited a TDP-43 kinase, casein kinase-1 (CK1), to GADD34.

64 ut not other PI3Kdelta inhibitors, inhibited casein kinase-1 epsilon (CK1epsilon).

65 We show that casein kinase-1 inhibition increases NMDA receptor activ

66 Conversely, pharmacological Casein Kinase-1 inhibition stabilizes REST, which in coo

67 Our data indicate that casein kinase-1 tonically regulates NMDA receptor activi

68 clock, a protein complex of frequency (FRQ), casein kinase 1a (CK1a), and the FRQ-interacting RNA Hel

69 the ability of FRQ to interact with WCC and casein kinase 1a.

70 t lenalidomide induces the ubiquitination of casein kinase 1A1 (CK1alpha) by the E3 ubiquitin ligase

71 The casein kinase 1A1 gene (CSNK1A1) is a putative tumor sup

72 We identified casein kinase 1alpha (CK1alpha) as a direct target of mi

73 iRNA kinome screen, we identify and validate casein kinase 1alpha (CK1alpha) as being responsible for

74 caused by GLIPR1-mediated redistribution of casein kinase 1alpha (CK1alpha) from the Golgi apparatus

75 demonstrate that RAS-dependent elevation of casein kinase 1alpha (CK1alpha) negatively regulates aut

76 trate that the destruction complex component casein kinase 1alpha (CK1alpha) phosphorylates Jade-1 at

77 Previous studies showed that casein kinase 1alpha (CK1alpha) stably associates with M

78 and metastasis in vivo via downregulation of casein kinase 1alpha (CK1alpha), a suppressor of pro-met

79 Here we report that casein kinase 1alpha (CK1alpha), a ubiquitously expresse

80 nhibitor), adenomatous polyposis coli (APC), casein kinase 1alpha (CK1alpha), and glycogen synthase k

81 inc finger proteins 1 (IKZF1) and 3 (IKZF3), casein kinase 1alpha (CK1alpha), and the translation ter

82 IFN in the context of intestinal knockout of casein kinase 1alpha (CK1alpha), which controls the ubiq

83 We thus propose that Casein kinase 1alpha is essential to allow beta-Catenin

84 ion in the beta-Catenin degradation complex, Casein Kinase 1alpha mutant cells accumulate beta-Cateni

85 , we could not detect any effect of the same Casein Kinase 1alpha mutation on Hedgehog signaling.

86 mor suppressor adenomatous polyposis coli or casein kinase 1alpha uncovered new regulatory features a

87 in-related protein 2, and the protein kinase Casein kinase 1alpha.

88 rvinium as a novel, potent (IC50, 10 nmol/L) casein kinase-1alpha (CK1alpha) agonist.

89 lycogen synthase kinase-3beta (GSK3beta) and casein kinase-1alpha (CK1alpha) are multifunctional kina

90 as carried out by the combined activities of casein kinase 1delta (CK1 delta) and casein kinase 1epsi

91 4 binding to the Gli1 locus is controlled by Casein Kinase 1delta (CK1 delta)-dependent phosphorylati

92 Casein kinase 1delta (CK1delta) and 1epsilon (CK1epsilon

93 Casein kinase 1delta (CK1delta) family members associate

94 is transition is marked by the appearance of casein kinase 1delta (CK1delta) in the nucleus.

95 89, while also enhancing Sid4's affinity for casein kinase 1delta (CK1delta).

96 Given the role of mammalian Hhp2 homologs, casein kinase 1delta and 1epsilon, in regulation of the

97 translational control of PERIOD stability by Casein Kinase 1delta and epsilon (CK1) plays a key regul

98 We and others have shown that casein kinase 1delta and epsilon (CK1delta/epsilon) are

99 ermined whether pharmacological targeting of casein kinase 1delta and epsilon (CK1delta/epsilon), key

100 n correlated with neurite outgrowth and that casein kinase 1delta, one of the enzymes that mediate Wn

101 ithin Rec8 as well as two different kinases, casein kinase 1delta/epsilon (CK1delta/epsilon) and Dbf4

102 Casein kinase 1delta/epsilon (CK1delta/epsilon) and thei

103 Earlier work has implicated casein kinase 1delta/epsilon as responsible for the Dvl

104 This activity was inhibited by a casein kinase 1delta/epsilon inhibitor, suggesting a rol

105 Casein kinases 1delta and epsilon are closely related cl

106 liver nuclei all three PERs, both CRYs, and Casein Kinase-1delta (CK1delta) are present together in

107 ties of casein kinase 1delta (CK1 delta) and casein kinase 1epsilon (CK1epsilon) and was antagonized

108 Specifically, we found that casein kinase 1epsilon (CK1epsilon) is highly expressed

109 In the present study, we found that casein kinase 1epsilon (CK1epsilon) was increased signif

110 pigment aggregation signaling also involved casein kinase 1epsilon (CK1epsilon), that both enzymes w

111 its vulnerability to degradation mediated by casein kinase 1epsilon (CSNK1E) is increased.

112 earing a short-period mutation in the enzyme casein kinase 1epsilon (tau mutation), which accelerates

113 Fat-Hippo signaling requires the Drosophila Casein kinase 1epsilon encoded by discs overgrown (Dco),

114 Here, we show that fission yeast Cki3 (a casein kinase 1gamma homolog) is a critical regulator to

115 es with thapsigargin (10 mum), inhibition of casein kinase 2 (4,5,6,7-tetrabromobenzotriazole; 10 mum

116 ific inhibitors of casein kinase 1 (CK1) and casein kinase 2 (CK2) (10 muM D4476, 100 muM CK2-inhibit

117 effects of mutant M1 spastins on FAT involve casein kinase 2 (CK2) activation.

118 urther, inhibition of claudin-2 by targeting casein kinase 2 (CK2) also ameliorated colitis.

119 We focus on casein kinase 2 (CK2) and demonstrate that the regulator

120 ave identified polo-like kinase 1 (Plk1) and casein kinase 2 (CK2) as two kinases of CLIP-170 and map

121 Casein kinase 2 (CK2) binds to the NHE3 C-terminus and c

122 Our previous results highlighted a role for casein kinase 2 (CK2) in the modulation of dopamine D1 r

123 iated stimulation, PTEN is phosphorylated by casein kinase 2 (CK2) in the Ser380-Thr382-Thr383 cluste

124 tified serine 358 as a specific site used by casein kinase 2 (CK2) in vitro and in vivo.

125 7 -: tetrabromobenzotriazole (TBB), a potent casein kinase 2 (CK2) inhibitor, as a strong suppressor

126 The protein kinase casein kinase 2 (CK2) is a pleiotropic and constitutivel

127 Casein kinase 2 (CK2) is known to regulate cell growth a

128 Although protein kinase casein kinase 2 (CK2) is readily detected in MKs and pla

129 Previous research suggests that casein kinase 2 (CK2) may be a promising therapeutic tar

130 Previous in vitro studies indicated that casein kinase 2 (CK2) mediated the phosphorylation of NS

131 We have previously shown that casein kinase 2 (CK2) negatively regulates dopamine D1 a

132 We demonstrated that increased activity of casein kinase 2 (CK2) observed in HPC and in MDSC could

133 ay is a key regulator of RUNX2 stability, as Casein kinase 2 (CK2) phosphorylates RUNX2, recruiting t

134 Casein kinase 2 (CK2) phosphorylates the NR2B subunit wi

135 The MRE11-PIH1D1 interaction is dependent on casein kinase 2 (CK2) phosphorylation of two acidic sequ

136 The Foxc2 amino terminus has a consensus casein kinase 2 (CK2) phosphorylation site at serine 124

137 ariant of the formin FHOD3 that introduces a casein kinase 2 (CK2) phosphorylation site.

138 and overexpression experiments, we show that casein kinase 2 (CK2) promotes stress granule dynamics.

139 that phosphorylation of recombinant TFIIF by casein kinase 2 (CK2) reduces or eliminates some of the

140 We also found that two putative casein kinase 2 (CK2) sites adjacent to IE2-SIM1 are pho

141 ctivated through pharmacologic inhibition of casein kinase 2 (CK2) to eradicate disease in high-risk

142 sh1 is phosphorylated by the Cka2 subunit of casein kinase 2 (CK2) to promote its E3 activity for Cse

143 CD5 activates casein kinase 2 (CK2), a serine/threonine kinase that co

144 ere, we report that Brg1 is also a target of casein kinase 2 (CK2), a serine/threonine kinase, in pro

145 wn previously to require the Cka2 subunit of casein kinase 2 (CK2), a ubiquitous enzyme with multiple

146 Casein kinase 2 (CK2), a ubiquitous kinase, regulates se

147 nsists of Daz interacting protein 1 (Dzip1), casein kinase 2 (CK2), and B56 containing protein phosph

148 on was dependent on XRCC1 phosphorylation by casein kinase 2 (CK2), enhancing XRCC1's interaction wit

149 on events catalyzed first by MEK and then by casein kinase 2 (CK2), followed by interaction with impo

150 e, and this phosphorylation was catalyzed by casein kinase 2 (CK2), the levels of which were dramatic

151 a striking resemblance to that of eukaryotic casein kinase 2 (CK2), which also exhibits dual nucleoti

152 d51 phosphorylation at threonine 13 (T13) by casein kinase 2 (CK2), which in turn triggers direct bin

153 ulator of Poll III (MAF1), via a synergistic casein kinase 2 (CK2)- and mammalian target of rapamycin

154 Wnt stimulation induces the casein kinase 2 (CK2)-dependent phosphorylation of LRP6

155 We have also noted that casein kinase 2 (CK2)-directed phosphorylation of Pax7 a

156 various kinases, including GPCR kinases and casein kinase 2 (CK2).

157 the unsuspected tyrosine kinase activity of casein kinase 2 (CK2).

158 ISA analyses and Western blotting to measure casein kinase 2 (CK2).

159 by the disease-relevant signalling protein, casein kinase 2 (CK2).

160 orylated on conserved serines 487 and 491 by casein kinase 2 (CK2).

161 minal kinase; (ii) inhibition of calpain and casein kinase 2 activity; and (iii) induction of fibrobl

162 Casein kinase 2 alpha phosphorylates PDCD5 at Ser-119 to

163 lation sites and two putative GRIP1 kinases, casein kinase 2 and cyclin-dependent kinase 9.

164 posttranslationally regulated by TNF-induced casein kinase 2 catalytic subunit (CK2alpha') phosphoryl

165 These data support a role for casein kinase 2 in regulation of protein synthesis by do

166 We report here that casein kinase 2 phosphorylates a conserved threonine res

167 Upon hypertrophic stimuli, casein kinase 2 phosphorylates DPF3a at serine 348.

168 We also show that casein kinase 2 phosphorylates G3BP1 at serine 149 in vi

169 Our experiments also disclosed that casein kinase 2 plays an integral role in Tpm phosphoryl

170 We now show that TFIIF phosphorylated by casein kinase 2 remains competent to support PIC assembl

171 Casein kinase 2 stimulates the biogenesis of Tom22 and T

172 an interacting protein, protein kinase C and casein kinase 2 substrate in neurons 1 (PACSIN1).

173 The PACSIN (protein kinase C and casein kinase 2 substrate in neurons) adapter proteins c

174 This activity, and the ability of casein kinase 2 to use GTP as a phosphate donor, may be

175 ine 424 by protein kinase CK2 (also known as casein kinase 2) activated the HDAC3 in vitro.

176 ylation of calmodulin by protein kinase CK2 (casein kinase 2) rapidly and reversibly modulated KCNQ2

177 overed that murine Arl13b is a substrate for casein kinase 2, a contaminant in our preparation from h

178 Protein kinase CK2 (CK2) (formerly casein kinase 2, a protein Ser/Thr kinase signal that is

179 ation of ErbB2 or loss of the betasubunit of casein kinase 2, shifted the whole population toward a f

180 uired Rab11-dependent trafficking and FAM20C/casein kinase 2-dependent C-terminal phosphorylation of

181 required for insulin induction of Sort1 in a casein kinase 2-dependent manner and that inhibition of

182 Casein kinase 2-mediated phosphorylation at VHL N-termin

183 ERK promotes casein kinase 2-mediated phosphorylation of alpha-cateni

184 hin TMVs through a process that requires the casein kinase 2-mediated phosphorylation of RanGAP1.

185 t we identified as substrates for Erk1/2 and casein kinase 2.

186 I, whereas Ca(V)1.1-T1579 is a substrate for casein kinase 2.

187 nts indicate that phosphorylation of TLE1 by casein kinase-2 (CK2) at Ser-239 and Ser-253 is necessar

188 Casein kinase-2 (CK2) promotes cell survival and is upre

189 Conversely, casein kinase-2 (CK2)-inhibitor increases Ikaros functio

190 s NMDA receptor activity by interacting with casein kinase-2 and protein phosphatases in the hypothal

191 he protein phosphatase 1/2A, calcineurin, or casein kinase-2 inhibitor.

192 M1-type muscarinic receptors and occur in a casein kinase-2-dependent manner.

193 of HIPK2's kinase domain bound to CX-4945, a casein kinase 2alpha (CK2alpha) inhibitor currently in c

194 Here, we show that G3BP1 phosphorylation by casein kinase 2alpha (CK2alpha) triggers G3BP1 granule d

195 In this study, we explored whether casein kinase 2alpha (CK2alpha), the human homolog of Ck

196 ated protein 1 (MRP1), is regulated by yeast casein kinase 2alpha (Cka1p) via phosphorylation at Ser2

197 orylation status of the downstream molecules casein kinase-2alpha and histone deacetylase 2 were sign

198 x1 regulates normal cardiac function via p27/casein kinase-2alpha/histone deacetylase 2 and indicate

199 e U.S. Food and Drug Administration-approved casein kinase activator, pyrvinium) in C57Bl/6J mice res

200 NUCKS1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) i

201 NUCKS1 (nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate 1) i

202 ly accepted that FAM20C functions as a Golgi casein kinase and has large numbers of kinase substrates

203 " with Axin, glycogen synthase kinase 3, and casein kinase, APC targets sscatenin (sscat) for phospho

204 e interacting proteins were found to contain casein kinase (CK) 2, phosphokinase (PK)C phosphorylatio

205 R2 is phosphorylated on Ser-662 and flanking casein kinase (CK) sites in vivo.

206 g peptide, we established a pivotal role for casein kinase (CK)-2-mediated circadian BMAL1-Ser90 phos

207 HDAC inhibitors transcriptionally activated casein kinase (CK)2alpha expression through increased as

208 Silencing N-myrystoyltransferase(NMT)-1 and casein-kinase-(CK)-II-alpha prevented Tat.AG- and HIV-1-

209 Increased levels of casein kinase (CK1 and CK2), which are associated with T

210 Casein kinase CK2 is an essential enzyme in higher organ

211 s of ataxia-telangiectasia-mutated (ATM) and casein kinases (CKs) 1 and 2.

212 y mechanistic target of rapamycin (mTOR) and casein kinase (CSNK)-2.

213 Finally, we identify and validate the casein kinase CSNK1A1 (also known as CK1alpha or CK1a) a

214 The casein kinase family of serine/threonine kinases regulat

215 , member C (Fam20C), formerly known as Golgi casein kinase (G-CK), which is exclusively resident in t

216 To assess the role of casein kinase I (CK1) in the regulation of dopamine sign

217 Although members of the casein kinase I (CKI) family phosphorylate alphaSyn at S

218 CK3, a gene that encodes a vacuolar membrane casein kinase I (CKI) homolog that nonredundantly functi

219 to growth signals, and in collaboration with casein kinase I (CKI), generates a phosphodegron that bi

220 t Pah1 is phosphorylated by the YCK1-encoded casein kinase I (CKI), regulating Pah1 catalytic activit

221 RQ), FRQ-interacting RNA helicase (FRH), and casein kinase I (CKI), which inhibits the activity of th

222 biquitination and destruction of VEGFR2 in a casein kinase I (CKI)-dependent manner.

223 -induced phosphorylation of its prodomain by casein kinase I (Yck1/2).

224 ion is dependent on Ptr3 and the integral PM casein kinase I (Yck1/2).

225 r a critical requirement for the centrosomal casein kinase I delta (CKIdelta) in centrosome transloca

226 Activating beta-catenin through Casein Kinase I inhibition or Wnt3A addition increased b

227 ing the phosphorylation of Vac17 via Yck3, a casein kinase I, and likely another unknown kinase.

228 ucleation pathway were identified as well as casein kinase I, which had a similar morphological RNAi

229 When HOPS is phosphorylated by the vacuolar casein kinase I, Yck3p, tethering only takes place when

230 Casein kinase I-alpha (CKI-alpha) was identified as an N

231 Set8 for ubiquitination and degradation in a casein kinase I-dependent manner, which is activated by

232 iod being exquisitely sensitive to levels of casein kinase I.

233 Casein kinase Ialpha (CKIalpha) directly phosphorylated

234 Following these changes, loss of Casein kinase Ialpha and induction of chronic DNA damage

235 ks, including three compounds that inhibited casein kinase Iepsilon in vitro and a unique benzodiazep

236 We conclude that Casein Kinase Iepsilon phosphorylation acts as a switch,

237 ylation events are independently mediated by Casein Kinase Iepsilon.

238 f the gilgamesh (gish) gene, which encodes a casein kinase Igamma homolog that is preferentially expr

239 lated protein [LRP] 5/6), dishevelled (dsh), casein kinase Igamma, G proteins, and Axin reduced gamma

240 t sites by at minimum two different kinases, casein kinase II (CK II) and tousled-like kinase (tlk).

241 for phosphorylation by protein kinase C and casein kinase II (CK-II).

242 ar substrates of human protein kinases (e.g. casein kinase II (CK2) and Akt), that implicated several

243 SARS-CoV-2 infection promoted casein kinase II (CK2) and p38 MAPK activation, producti

244 s presented here identify the protein kinase casein kinase II (CK2) as a BMP receptor type Ia (BRIa)

245 Here we uncover a novel role for casein kinase II (CK2) in the cellular response to hyper

246 -dione derivatives were synthesized as human casein kinase II (CK2) inhibitors.

247 that the conserved serine/threonine kinase, casein kinase II (CK2), promotes miRISC function in Caen

248 y, Brd4 association with p53 is modulated by casein kinase II (CK2)-mediated phosphorylation of a con

249 The N-terminal phosphorylation by cellular casein kinase II (CKII) at S21, T32, and S43, and other

250 roaches, we have identified a novel role for casein kinase II (CKII) in the modification of the polym

251 We have demonstrated that casein kinase II (CKII) is involved in the phosphorylati

252 Casein kinase II (CKII) phosphorylates MLL1 proximal to

253 hat lipin 1beta is a bona fide substrate for casein kinase II (CKII), a protein kinase that is essent

254 ed the phosphorylation of Dgk1 DAG kinase by casein kinase II (CKII).

255 s work, we show that Pah1 is a substrate for casein kinase II (CKII); its phosphorylation was time- a

256 Casein kinase II (formerly known as CK2), a ubiquitous S

257 c for CKI, whereas the others were shared by casein kinase II (Ser-705), Cdc28-cyclin B (Ser-602), Ph

258 damage in a manner dependent on TCOF1 and on casein kinase II and ATM, which are known to modify TCOF

259 In vitro studies support roles for casein kinase II and PKC in this modification, consisten

260 this repression by directly interacting with Casein Kinase II and preventing it from activating HDAC3

261 phorylated by two EVI1 interactome proteins, casein kinase II and protein phosphatase-1alpha.

262 Thr1704-sites of phosphorylation by PKA and casein kinase II at the interface between the proximal a

263 RNA designed to knock down expression of the casein kinase II beta-subunit gene family lengthens peri

264 t with previous reports of a short period in casein kinase II beta-subunit overexpressors.

265 phosphatase calcineurin (TAX-6), and of the casein kinase II homologue KIN-10.

266 preincubation of RBCs with DMAT, a specific casein kinase II inhibitor.

267 dition, our data indicate that inhibition of casein kinase II or GSK3beta significantly reduced hnRNP

268 uniquely possess lysine residues following a casein kinase II phosphorylation motif which is critical

269 Mutations of the casein kinase II phosphorylation site caused a complex p

270 es these activities, which are stimulated by Casein Kinase II phosphorylation, are unknown.

271 serine 72 and pharmacological inhibition of casein kinase II reduced GTPCH-1 phosphorylation and blu

272 ll three members of the protein kinase C and casein kinase II substrate in neurons (PACSIN) family an

273 ously reported that the protein kinase C and casein kinase II substrate in neurons (PACSIN) forms a c

274 ned the role of protein kinase CK2 (formerly casein kinase II) in increased N-methyl-d-aspartate rece

275 ng 1 (YY1) in vitro and in vivo by CK2alpha (casein kinase II), a multifunctional serine/threonine pr

276 se A/calcium calmodulin-dependent kinase II, casein kinase II, and proline-directed kinase, indicatin

277 Ser184 of Geminin could be phosphorylated by Casein kinase II, resulting in the enhanced binding to H

278 on of myosin light chain kinase (P<0.05) and casein kinase II-alpha (P=0.06).

279 EGF enhanced secretion of AMF through its casein kinase II-mediated phosphorylation.

280 , which in turn increases enzyme activity of casein kinase II.

281 ivity) is inactivated via phosphorylation by casein kinase II.

282 P<0.0001) through a mechanism that includes casein kinase II.

283 tivity and its subsequent phosphorylation by casein kinase II.

284 ain binding to Asf1-T(270) phosphorylated by casein kinase II.

285 Dual mutation of Ser1700 and a nearby casein-kinase II site (Thr1704) caused accelerated hyper

286 and signaling pathways, including CaMK, PKA, Casein kinase-II, and the Raf-MEK-ERK and PI-3K-Akt path

287 RNA synthesis through the phosphorylation of casein kinase IIalpha (CK2alpha) on a threonine residue

288 Casein kinase Ivarepsilon phosphorylates the S102 in thi

289 Casein kinase levels were not altered after treatment wi

290 e WC complex in the nucleus by promoting the casein kinases-mediated WC phosphorylation.

291 n HapMap cell lines was protein kinase C and casein kinase substrate in neurons 2 (PACSIN2).

292 or by coexpression with protein kinase C and casein kinase substrate in neurons 3 (PACSIN3), a regula

293 HSP90, only Ser(289) could be identified as casein kinase target by mass spectrometry.

294 Fam20C is the Golgi casein kinase that phosphorylates secretory pathway prot

295 Fam20C appears to be the Golgi casein kinase that phosphorylates secretory pathway prot

296 Fam20C is the physiological Golgi casein kinase, which phosphorylates many secreted protei

297 We report here that the redundant casein kinases Yck1p and Yck2p phosphorylate sites withi

298 at this process is regulated in yeast by the casein kinase Yck3, which phosphorylates Mon1 and blocks

299 e requires its phosphorylation by the type 1 casein kinase Yck3.

300 The yeast casein kinases (Ycks) are key players in this pathway.