ライフサイエンスコーパス: catabolite repression

1 ntermediary metabolism in Escherichia coli ("catabolite repression").

2 ernative carbon sources is shut down, due to catabolite repression.

3 grown in media containing sugars that cause catabolite repression.

4 lated by agmatine induction and carbohydrate catabolite repression.

5 tabolism, are subject to direct Crp-mediated catabolite repression.

6 or limiting, a phenomenon known as nitrogen catabolite repression.

7 Synthesis of this activity is subject to catabolite repression.

8 r exclusion mechanisms of succinate-mediated catabolite repression.

9 least some competence genes are regulated by catabolite repression.

10 is is a major transcription factor mediating catabolite repression.

11 The tdc operon is subject to CRP-controlled catabolite repression.

12 opic developmental processes, but not carbon catabolite repression.

13 on of an array of functions including carbon catabolite repression.

14 tified in the promoter region, indicative of catabolite repression.

15 or citrate synthase and is subject to carbon catabolite repression.

16 enase, which is regulated in both species by catabolite repression.

17 dia with much agitation, CcpA alone mediated catabolite repression.

18 ional cofactor controlling the phenomenon of catabolite repression.

19 itrate fermentation was under the control of catabolite repression.

20 cally induced by gluconate and repressed via catabolite repression.

21 oth of which contribute to the phenomenon of catabolite repression.

22 lis cells to screen for mutants resistant to catabolite repression.

23 hat the toxin genes are subject to a form of catabolite repression.

24 insensitive to transcriptional regulation by catabolite repression.

25 on, CcpB and CcpA both proved to function in catabolite repression.

26 ariations in cell growth rate rather than to catabolite repression.

27 ption mutant is highly sensitive to nitrogen catabolite repression.

28 es in appropriate locations to exert glucose catabolite repression.

29 phosphorylation at His-15 can prevent carbon catabolite repression.

30 lated by the SOS response, anaerobiosis, and catabolite repression.

31 gluconate and is subject to fourfold glucose catabolite repression.

32 table alanyl residue are resistant to carbon catabolite repression.

33 s operon is also believed to be regulated by catabolite repression.

34 lation of numerous transcripts during carbon catabolite repression.

35 s regulatory phenomenon is defined as carbon catabolite repression.

36 source, glucose, in a process called carbon catabolite repression.

37 g very weakly transcribed genes under strong catabolite repression.

38 others through a regulatory mechanism termed catabolite repression.

39 h gene, the DMML encoding gene is subject to catabolite repression.

40 ns with a hpr(H22A) allele exhibited relaxed catabolite repression.

41 rating that HPr-His22-P is needed for strong catabolite repression.

42 trol region cloned in E. coli was subject to catabolite repression.

43 scriptome appeared to be regulated by carbon catabolite repression.

44 r region showed that both CREs contribute to catabolite repression.

45 efficient microbial conversion due to carbon catabolite repression.

46 activity were shown to be refractory to such catabolite repression.

47 ubiquitin ligase, interferes with the carbon catabolite repression 4 (CCR4)-negative on TATA-less (NO

48 ecay and is primarily mediated by the CARBON CATABOLITE REPRESSION 4 (CCR4)-NEGATIVE ON TATA-LESS (NO

49 oreover, consistent with a classical role in catabolite repression, a cAMP-CRP-dependent reporter sho

50 CcpA (catabolite control protein A)-mediated catabolite repression, a global regulatory mechanism in

51 implications for mechanisms of CRP-dependent catabolite repression acting in conjunction with a membe

52 es), chemotaxis (methyl-accepting proteins), catabolite repression (adenylate cyclases), and modulati

53 he chromosome was barely sensitive to carbon catabolite repression, although the H15A mutant HPr can

54 These results suggest that catabolite repression and anaerobic repression of citZ a

55 e in gntT expression which is independent of catabolite repression and binding of GntR to the operato

56 ) operon of Escherichia coli is regulated by catabolite repression and by tryptophan-induced inhibiti

57 ) operon of Escherichia coli is regulated by catabolite repression and by tryptophan-induced transcri

58 ) operon of Escherichia coli is regulated by catabolite repression and by tryptophan-induced transcri

59 iration, in addition to their known roles in catabolite repression and carbon source utilization in o

60 nase/phosphorylase, are primary mediators of catabolite repression and catabolite activation in Bacil

61 ) is a global regulatory protein involved in catabolite repression and glucose activation in Gram-pos

62 ritical role for the PTS in CcpA-independent catabolite repression and induction of cel gene expressi

63 ssion of fruA is under the control of carbon catabolite repression and is induced by growth in fructa

64 itoring and use that information to regulate catabolite repression and related responses.

65 in stable environments, with more stringent catabolite repression and slower transcriptional reprogr

66 t that His-15 of HPr is important for carbon catabolite repression and that either mutation or phosph

67 ted that CcpA was essential for carbohydrate catabolite repression and that Flp was required for opti

68 s finding suggests that ure1 is regulated by catabolite repression and that limiting glucose in urine

69 moter was previously shown to be a target of catabolite repression and the binding site for a putativ

70 metabolic phenotype depends on the level of catabolite repression and the metabolic state-dependent

71 ) operon in Escherichia coli is regulated by catabolite repression and tryptophan-induced transcripti

72 e operon of Escherichia coli is regulated by catabolite repression and tryptophan-induced transcripti

73 ) operon of Escherichia coli is regulated by catabolite repression and tryptophan-induced transcripti

74 ) operon of Escherichia coli is regulated by catabolite repression and tryptophan-induced transcripti

75 ) operon of Escherichia coli is regulated by catabolite repression and tryptophan-induced transcripti

76 cpA), a highly conserved regulator of carbon catabolite repression and virulence in a number of gram-

77 atabolism, chemotaxis, glycogen utilization, catabolite repression, and inducer exclusion.

78 dependent of the SOS response, anaerobiosis, catabolite repression, and integration host factor as we

79 ulating central carbon metabolism and carbon catabolite repression, and is a frequent target of metab

80 ng mechanisms of signal transduction, carbon catabolite repression, and quorum-sensing.

81 ed in Bacillus subtilis global carbon source catabolite repression, and the ptsH1 mutation in the gen

82 d thus Rho-dependent termination rather than catabolite repression appears to be the event influenced

83 role in abpA expression, other mechanisms of catabolite repression are present.

84 Genes subject to CcpA-independent catabolite repression are primarily concerned with sporu

85 Using carbon catabolite repression as a case study, we describe how p

86 tion of HPr at Ser-46 is required for carbon catabolite repression as ptsH1 mutants in which Ser-46 o

87 is protein is a major factor responsible for catabolite repression at the nrf promoter, and Fis can o

88 In order to identify the mechanism of catabolite repression by glucose, a mutation was introdu

89 In addition to catabolite repression by glucose, l-leucine acts by inhi

90 s of gluconate (gnt) and xylose (xyl) operon catabolite repression by glucose, mannitol, and sucrose.

91 er finding that tdc expression is subject to catabolite repression by intermediary metabolites, stron

92 suggests that Pyk may participate in glucose catabolite repression by serving among all of the factor

93 nd G6PDH activity are known to be subject to catabolite repression by succinate.

94 ate that propionate metabolism is subject to catabolite repression by the global transcriptional regu

95 Deletion of hprK in S. meliloti enhanced catabolite repression caused by succinate, as did an S53

96 Carbon catabolite repression (CCR) allows bacteria to alter met

97 s mannose and glucose, is involved in carbon catabolite repression (CCR) and regulates the expression

98 olite control protein (CcpA) mediates carbon catabolite repression (CCR) by controlling expression of

99 REs), which have been shown to govern carbon catabolite repression (CCR) by functioning as negative c

100 riptional regulator that accounts for carbon catabolite repression (CCR) control of the anaerobic cat

101 CcpA is the global mediator of carbon catabolite repression (CCR) in gram-positive bacteria, a

102 , two regulatory genes that carry out carbon catabolite repression (CCR) in staphylococci and other G

103 Carbohydrate catabolite repression (CCR) in Streptococcus mutans can

104 Carbon catabolite repression (CCR) is a regulatory phenomenon i

105 Carbon catabolite repression (CCR) is a regulatory phenomenon o

106 In many bacteria, carbon catabolite repression (CCR) is central to such regulatio

107 Carbon catabolite repression (CCR) is one of the most fundament

108 In Bacillus subtilis, CcpA-dependent carbon catabolite repression (CCR) mediated at several cis-acti

109 In Bacillus subtilis, carbon catabolite repression (CCR) of many genes is mediated at

110 btilis mutant that partially relieves carbon catabolite repression (CCR) of the hut operon was isolat

111 ortunistic pathogen uses a different, carbon catabolite repression (CCR) strategy than many, model mi

112 ilm formation were under some form of carbon catabolite repression (CCR), a regulatory network in whi

113 so includes inhibited glycolysis, and carbon catabolite repression (CCR)-mediated carbohydrate-depend

114 ntegral to pneumococcus's strategy of carbon catabolite repression (CCR).

115 by a complex regulatory pathway named carbon catabolite repression (CCR).

116 ated that CcpA plays a direct role in carbon catabolite repression (CCR).

117 , is known as carbon catabolite and nitrogen catabolite repression (CCR, NCR), and has been shown to

118 3 in-frame deletion mutants show a relief of catabolite repression compared to the wild type.

119 nce participate in the formation of the CcpA catabolite repression complex at cre sites.

120 ossible that induction of plcH is subject to catabolite repression control (CRC) by tricarboxylic cyc

121 s distal binding side, and together with the catabolite repression control (Crc) protein, assembles i

122 We show that the catabolite repression control (Crc) protein, which plays

123 is was apparently not due to a defect in the catabolite repression control (Crc) protein.

124 In this study, the role of Crc in catabolite repression control has been studied in Pseudo

125 The gene (crc) responsible for catabolite repression control in Pseudomonas aeruginosa

126 The effect of growth in 2xYT medium on catabolite repression control in Pseudomonas putida has

127 This suggests that the mechanism of catabolite repression control in rich media by Crc invol

128 dulates substrate prioritization through the catabolite repression control pathway.

129 nas aeruginosa the RNA chaperone Hfq and the catabolite repression control protein (Crc) govern trans

130 slocator (ArsB), superoxide dismutase (SOD), catabolite repression control protein (Crc), or glutathi

131 Crc (catabolite repression control protein) was shown to be r

132 Crc (catabolite repression control) protein of Pseudomonas ae

133 a xylose catabolic activation independent of catabolite repression control.

134 For succinate and lactose, the loss of catabolite repression could be attributed to the constit

135 Consistent with catabolite repression (CR), a DNA sequence with high hom

136 tor (arcA and etrA [fnr homolog]) and carbon catabolite repression (crp and cya) proteins affect arse

137 ative intensities of CcpA- and CcpB-mediated catabolite repression depended on growth conditions.

138 sing conditions, demonstrating that nitrogen catabolite repression does not influence dimorphism.

139 The cyclic AMP (cAMP)-dependent catabolite repression effect in Escherichia coli is amon

140 lted in partial relief of succinate-mediated catabolite repression, extreme sensitivity to cobalt lim

141 in the nucleus, thereby activating nitrogen catabolite repression genes.

142 cally relieved glucose- and sucrose-promoted catabolite repression, (ii) reduced the growth rate in m

143 a transcriptional regulator known to mediate catabolite repression in a number of low-G+C-content gra

144 tein IIA(Glc) plays a key regulatory role in catabolite repression in addition to its role in the vec

145 he sole signaling molecule for CcpA-mediated catabolite repression in B. subtilis.

146 g the process of sugar import via the PTS to catabolite repression in bacilli.

147 ant physiological roles, ranging from carbon catabolite repression in bacteria to mediating the actio

148 se-pairing RNA Spot 42 plays a broad role in catabolite repression in Escherichia coli by directly re

149 ENR to the regulatory network behind carbon catabolite repression in Escherichia coli is presented.

150 lect an aspect of a more global mechanism of catabolite repression in L. monocytogenes.

151 The loss of catabolite repression in lacR mutants was seen in cells

152 tate of which is the control point of carbon catabolite repression in low G+C Gram-positive bacteria.

153 These mutants suggested that catabolite repression in pseudomonads might, in part, in

154 gether with the Hfq protein, participates in catabolite repression in pseudomonads, helping to coordi

155 ne-22 residue, and that HPr-His22-P enhances catabolite repression in the presence of succinate.

156 although the carbon sources responsible for catabolite repression in the two species differ.

157 luorescens, suggesting a common mechanism of catabolite repression in these three species.

158 n enteric bacteria, the key player of carbon catabolite repression is a component of the glucose-spec

159 In addition, the carbon catabolite repression is alleviated by protease-based in

160 In Sinorhizobium meliloti, catabolite repression is influenced by a noncanonical ni

161 CcpA to inhibit transcription suggests that catabolite repression is not simply caused by CcpA bindi

162 Here, we show that this catabolite repression is relieved by mutations that weak

163 mpared with a relatively weak role in carbon catabolite repression, is similar to the role of RCO1 in

164 c archaeon Sulfolobus solfataricus employs a catabolite repression-like regulatory system to control

165 ction seen in this organism indicates that a catabolite repression-like system is present in a member

166 The archaeon Sulfolobus solfataricus uses a catabolite repression-like system to control production

167 nes are substrate inducible and sensitive to catabolite repression, mediated through ArcR and CcpA, r

168 the parent H26 and glpK mutant strains, with catabolite repression more pronounced in the glycerol ki

169 circuit responsible for regulating nitrogen catabolite repression (NCR) in yeast.

170 Nitrogen catabolite repression (NCR) is the basis of this selecti

171 e factors regulate transcription of nitrogen catabolite repression (NCR) sensitive genes when preferr

172 en use is mediated in large part by nitrogen catabolite repression (NCR), which results in the repres

173 gnal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5)

174 and Deh1p mediate the regulation of nitrogen catabolite repression (NCR)-sensitive gene expression in

175 hey bind GATA sequences upstream of nitrogen catabolite repression (NCR)-sensitive genes and activate

176 of Gln3 and Gat1, the activators of nitrogen catabolite repression (NCR)-sensitive genes whose produc

177 ities is transcriptional control of nitrogen catabolite repression (NCR)-sensitive genes.

178 ressors (Dal80p and Deh1p) regulate nitrogen catabolite repression (NCR)-sensitive transcription in S

179 Gln3 intracellular localization and nitrogen catabolite repression (NCR)-sensitive transcription in S

180 Nitrogen catabolite repression (NCR)-sensitive transcription is a

181 Gln3, the major activator of nitrogen catabolite repression (NCR)-sensitive transcription, is

182 riptional activator responsible for nitrogen catabolite repression (NCR)-sensitive transcription, per

183 ulates in the nucleus, and mediates nitrogen catabolite repression (NCR)-sensitive transcription.

184 Expression of these latter genes is nitrogen catabolite repression (NCR)-sensitive, i.e. expression i

185 This regulation is designated nitrogen catabolite repression (NCR).

186 a physiological process designated nitrogen catabolite repression (NCR).

187 r ones through a process designated nitrogen catabolite repression (NCR).

188 es whose expression is sensitive to nitrogen catabolite repression (NCR).

189 ogical response has been designated nitrogen catabolite repression (NCR).

190 ogical response has been designated nitrogen catabolite repression (NCR).

191 Catabolite repression of a number of catabolic operons i

192 CcpA, which is responsible for catabolite repression of a number of secondary carbon so

193 ) may be involved in but is not required for catabolite repression of alpha-amylase, indicating that

194 Catabolite repression of ctaBCD'-lacZ was partly depende

195 f the ccpA gene had no discernible effect on catabolite repression of fruA.

196 ans-acting factors involved in induction and catabolite repression of fruA.

197 Catabolite repression of galactose by glucose is one of

198 Additionally, Crp mediates strong indirect catabolite repression of many cytoplasmic stress respons

199 lot experiments also showed that there is no catabolite repression of nanE-nanA transcription by gluc

200 d growth phenotype was reflected in a strong catabolite repression of pauA promoter activation by CAD

201 protein, but was not necessary for nitrogen catabolite repression of peptide import or PTR2 expressi

202 for the HPr protein was reported to relieve catabolite repression of several genes.

203 ent work has shown that in Bacillus subtilis catabolite repression of several operons is mediated by

204 and that this mechanism in part accounts for catabolite repression of sigma(L)-directed levD operon e

205 rulation in C. perfringens, glucose-mediated catabolite repression of sporulation is not due to the a

206 CreA-dependent carbon catabolite repression of starch and ethanol utilization

207 Synergistic carbon catabolite repression of the Bacillus subtilis aconitase

208 Carbon catabolite repression of the Bacillus subtilis citrate s

209 hromosomal bkdR-lacZ fusion, suggesting that catabolite repression of the bkd operon was the result o

210 enes; (iii) CcpA plays little direct role in catabolite repression of the cel regulon, but loss of sp

211 Carbon catabolite repression of the gnt operon of Bacillus subt

212 endent phosphorylation, also prevents carbon catabolite repression of the gnt operon.

213 mutants that had abnormal succinate-mediated catabolite repression of the melA-agp genes, which are r

214 Catabolite repression of the tricarboxylic acid (TCA) cy

215 f highly expressed genes that are subject to catabolite repression or activation mediated by the cycl

216 richia coli growing on sugars that result in catabolite repression or amino acids that feed into glyc

217 on this enzymatic activity or the canonical catabolite repression pathway, but likely does require s

218 ylation by modulating activity of the carbon catabolite repression pathway, in which the Hfq/Crc comp

219 form of a negative regulator of the nitrogen catabolite repression pathway, Ure2p.

220 substitution into HPr alleviated the strong catabolite repression phenotypes of strains carrying Del

221 se or casamino acids, suggesting that carbon catabolite repression plays a role in regulating xynA.

222 by negative feedback on glpK expression via catabolite repression, possibly to prevent methylglyoxal

223 al abscess formation, indicating that carbon catabolite repression presents an important pathogenesis

224 We linked this to indirect regulation of the catabolite repression protein Crc via the non-coding RNA

225 pts by forming a regulatory complex with the catabolite repression protein Crc.

226 as luxS and ompX and provide a link between catabolite repression, quorum sensing, and nitrogen assi

227 Catabolite repression regulates transcription initiation

228 e master transcriptional regulator of carbon catabolite repression/regulation (CCR).

229 itrogen sources in combination with nitrogen catabolite repression regulatory proteins.

230 wth on non-glucose substrates as part of the catabolite-repression response.

231 The other mutants display less stringent catabolite repression, resulting in leaky expression of

232 l (PRC1) vacuolar protease genes is nitrogen catabolite repression sensitive and is regulated by the

233 -responsive) and TorC1-independent (nitrogen catabolite repression-sensitive and methionine sulfoximi

234 Gln3p is a nitrogen catabolite repression-sensitive GATA-type transcription

235 sequences situated upstream of all nitrogen catabolite repression-sensitive genes that encode enzyme

236 eving Gln3 nuclear localization and nitrogen catabolite repression-sensitive transcription in respons

237 family DNA binding proteins mediate nitrogen catabolite repression-sensitive transcription in Sacchar

238 ontaining UASNTR sites that mediate nitrogen catabolite repression-sensitive transcription, and the s

239 Gln3-Myc13 nuclear accumulation and nitrogen catabolite repression-sensitive transcription, generate

240 s leads to an increase in succinate-mediated catabolite repression (SMCR).

241 carbon sources is termed succinate-mediated catabolite repression (SMCR).

242 s of various mechanisms for glucose control (catabolite repression, specific repression, and inducer

243 in carbon source can favor different carbon catabolite repression strategies.

244 icomponent phosphorelay system that controls catabolite repression, sugar transport and carbon metabo

245 The nanATEK operon is controlled by catabolite repression, suggesting that diminished expres

246 concluded that the components of the carbon catabolite repression system are essential to regulating

247 otA gene expression regulated by, the carbon catabolite repression system.

248 utations also increase glycerol-induced auto-catabolite repression that reduces glpK transcription in

249 tions to illustrate systemic effects such as catabolite repression, the aerobic/anaerobic diauxic shi

250 t cyclic-di-GMP may play a role in mediating catabolite repression, thereby facilitating the expressi

251 PTS) of gram-positive bacteria and regulates catabolite repression through phosphorylation/dephosphor

252 nd uptake in Escherichia coli are subject to catabolite repression through the cyclic AMP (cAMP)-CRP

253 l a key physiological role of cAMP-dependent catabolite repression: to ensure that proteomic resource

254 f some cellulases and hemicellulases, that a catabolite repression type of mechanism regulates cellul

255 preferred carbon source, succinate can exert catabolite repression upon genes needed for the utilizat

256 d by glucose but not by fructose, suggesting catabolite repression via two cre-like sequences identif

257 Sucrose-dependent catabolite repression was also evident in strains contai

258 otein 30% identical to CcpA, and relief from catabolite repression was shown to be due to the absence

259 o glucose-promoted but not mannitol-promoted catabolite repression were identified.

260 ivity is controlled by a mechanism of carbon catabolite repression, which directly controls the virul