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1 esterol homeostasis, and, finally, how it is catabolized.
2 ocrine cycle, whereas the internalized Hb is catabolized.
3 s then deactivated by CYP24A1 and ultimately catabolized.
4 hich cytoplasmic proteins and organelles are catabolized.
6 talk with the vitamin D-responsive gene that catabolizes 25-hydroxy-vitamin D and 1,25-dihydroxyvitam
10 owever, strains NCTC 8325 and N315 failed to catabolize acetate during the postexponential growth pha
11 ations can alter the ability of S. aureus to catabolize acetate, a surprising discovery, as TCA cycle
15 lase) constitute the majority of the sucrose-catabolizing activity; however, mutations in any one of
18 apyrase that inhibits platelet activation by catabolizing ADP released from damaged tissues and blood
21 owth in human saliva and in their ability to catabolize alpha-glucans digested by purified human sali
24 tend the previous evidence that BCAAs can be catabolized and serve as respiratory substrates at multi
26 argeting the metabolic pathways that import, catabolize, and synthesize essential cellular components
27 GlcNAc must be phosphorylated by Hxk1 to be catabolized, and also for it to enter the anabolic pathw
32 molecules found in vivo have been partially catabolized at either the E(1480)-(1481)G or E(1667)-(16
36 roxylase) was significantly increased, which catabolizes both 25(OH)VD(3) and 1alpha,25-hydroxyvitami
41 ites taken up by proliferating cells are not catabolized, but instead are used as building blocks dur
43 ptide hormone released by adipocytes, can be catabolized by adipose angiotensin-converting enzyme 2 (
44 ese results demonstrate that 15d-PGJ2 can be catabolized by Aor, thereby attenuating subsequent Nrf2
45 torage organelles that in hepatocytes may be catabolized by autophagy for use as an energy source, bu
46 per year(1,2), an estimated 10% of which is catabolized by bacteria through the DMSP cleavage pathwa
47 ylsulfoniopropionate (DMSP) is thought to be catabolized by bacteria via the DMSP demethylation pathw
51 mine has emerged as a metabolic fuel that is catabolized by mitochondrial glutaminase to support tumo
54 low-glucose and hypoxic conditions, proline catabolized by POX was used preferentially for ATP produ
60 line, and associated organic acids) were not catabolized by the the frdA::cat(+) strain, indicating t
64 t be tightly regulated, e.g., by agents that catabolize cAMP or inhibit its production (PDE4, mGluR3)
67 a lysosomal machinery-dependent process that catabolizes cellular components/organelles and proteins
68 by the mature host: each night the symbionts catabolize chitin released from hemocytes (phagocytic im
69 in the body do not express the capability of catabolizing cholesterol, so cholesterol efflux is essen
70 first time the capacity of adipose tissue to catabolize circulating BCAAs in vivo and that coordinate
72 Moreover, fasting upregulated the vitamin D catabolizing CYP24A1 in the kidney through the PGC-1alph
74 SINE) transcripts are elevated, whereas SINE-catabolizing DICER1 is reduced, in diabetic cells and mi
75 s colonized by a dense community of microbes catabolizing dietary and host carbohydrates during their
79 Finally, we show that a mutant unable to catabolize dl-alanine displays decreased competitiveness
80 dA, DmdB, DmdC and DmdD/AcuH, which together catabolize DMSP to acetylaldehyde and methanethiol as ca
82 tial depletion of glycogen reserves which is catabolized during freezing to produce cryoprotective co
83 epatocytes reside on the sER, LDs can now be catabolized efficiently to provide triglyceride for lipo
84 ocess by which cytoplasmic organelles can be catabolized either to remove defective structures or as
87 S, with corresponding reduction of vitamin D catabolizing enzyme (24-hydorxylase) expression in the C
89 to identify inhibitors of S. mansoni NAD(+) catabolizing enzyme (SmNACE), a receptor enzyme suspecte
91 results establish FAAH-2 as a bone fide NAE-catabolizing enzyme and suggest that NAE inactivation is
95 s of fasted mice, we observed decreased BCAA-catabolizing enzyme expression and increased circulating
96 ating BCKAs with concomitant changes in BCAA-catabolizing enzyme expression only in the skeletal musc
97 B cell-intrinsic induction of the tryptophan-catabolizing enzyme IDO1 is a key mechanism limiting TI
98 e by a mechanism dependent on the tryptophan catabolizing enzyme indoleamine 2,3 dioxygenase 1 (IDO1)
101 induced splenic expression of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
102 human cells to produce the tryptophan (Trp)-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
103 -gamma) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) i
104 ata, is a potent inhibitor of the tryptophan catabolizing enzyme indoleamine-2,3-dioxygenase (IDO).
107 ybrid screening, we identified the polyamine catabolizing enzyme spermidine/spermine N(1)-acetyltrans
108 airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermine N1-acetyltransfe
109 2,3-dioxygenase (IDO1) is a tryptophan (Trp)-catabolizing enzyme which is assumed to be instrumental
110 dent mechanisms; however, loss of the PGE(2)-catabolizing enzyme, 15-hydroxyprostaglandin dehydrogena
111 gs, increased colonic expression of the atRA-catabolizing enzyme, CYP26A1, correlated with reduced fr
113 ation of CYP26A1, a major retinoic acid (RA)-catabolizing enzyme, has recently been shown in cancer.
116 evidence for FA-mediated regulation of BCAA-catabolizing enzymes and BCKA content and highlights the
122 ding the upstream regulator KLF15, aminoacid catabolizing enzymes, notably proline dehydrogenase (POX
126 nds on the ability of microglia to sense and catabolize extracellular ATP, which is released upon neu
127 lternatively, the function of NACE may be to catabolize extracellular NAD(+) to prevent its use by ho
128 eria may be highly active protein degraders, catabolizing extracellular peptides while recycling nitr
130 d that the iron storage protein ferritin can catabolize folate in vitro and in vivo, and increased he
132 cytes overinduced heme oxygenase-1 (HO-1) to catabolize free heme in building up defense against this
133 -CEHC) in urine, feces, and plasma that were catabolized from administered oral d3- and intravenous d
134 of breast-to-brain metastases to take up and catabolize GABA into succinate with the resultant format
135 , possess an enrichment of gut bacteria that catabolize galactose, an end product of lactose metaboli
137 nd 4 have important roles in CNS function by catabolizing gangliosides and preventing their storage i
142 ypic effect on the ability of the variant to catabolize glucose, consistent with a modification in th
150 esizing this pathogen harbors robust ways to catabolize heme, we characterize two new intracellular h
151 pathogenic bacterium Neisseria meningitidis catabolizes heme for the iron necessary for infection.
153 ively express heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(2+), and car
154 ucible enzyme heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(2+), and car
157 falciparum invades red blood cells, where it catabolizes hemoglobin and sequesters the released toxic
163 and protein stores available in autumn were catabolized in proportion to their availability above a
165 that the essential amino acid tryptophan is catabolized in the tumor tissue by the rate-limiting enz
167 ranscription microarray results, D-serine is catabolized into acetate via the phosphotransacetylase (
168 Their actions are terminated when they are catabolized into inactive fragments by at least three di
170 cells (SCs), we found that autophagy, which catabolizes intracellular contents to maintain proteosta
171 cidating the pathway by which cholesterol is catabolized is necessary to understand the molecular mec
172 ulate glycine betaine for osmoprotection and catabolize it as a growth substrate, but how they regula
174 involving nonphosphorylated intermediates to catabolize L-arabinose via an L-arabinose dehydrogenase,
175 d that E. coli LF82 shifts its metabolism to catabolize L-serine in the inflamed gut in order to maxi
177 human malaria parasite Plasmodium falciparum catabolizes large quantities of host-cell hemoglobin in
180 propose that the excess PC thus generated is catabolized, leading to TG synthesis and steatosis by wa
181 is of enzymes that are used to transport and catabolize less preferred carbon sources is repressed in
183 train SYK-6 of the bacterium Sphingobium sp. catabolizes lignin-derived biphenyl via a meta-cleavage
187 d particulate matter but are also crucial in catabolizing lung surfactant, a lipid-protein complex th
189 ysiological stress impacts animal fitness by catabolizing metabolic stores and suppressing reproducti
191 stridium difficile, use a common strategy of catabolizing microbiota-liberated mucosal carbohydrates
192 a variety of additional S-nitrosothiols were catabolized more readily by A4V SOD than by WT SOD.
193 edlings revealed that seed storage lipid was catabolized more slowly, long-chain acyl-CoA substrates
194 lthough more than 95% of incoming mannose is catabolized, most of the mannose released by intracellul
196 reductase/myo-inositol oxygenase (RSOR/MIOX) catabolizes myo-inositol and is implicated in the pathog
200 uestration into ischemic cerebral tissue, by catabolizing nucleotides released by injured cells, ther
209 gs to a superfamily of Nudix hydrolases that catabolize potentially toxic compounds in the cell.
210 nt Bradyrhizobium japonicum strain unable to catabolize Pro (Pro dehydrogenase(-) [ProDH(-)]) resulte
211 inoculated with the mutant strain unable to catabolize Pro or take up H(2) (ProDH(-), hup(-)) than i
212 oxyprostaglandin dehydrogenase (HPGD), which catabolizes prostaglandin E(2) (PGE(2)) into the metabol
214 s constitute the major cellular systems that catabolize proteins to recycle free amino acids for ener
216 umber of Gram-negative bacteria are known to catabolize quinate and shikimate, only limited informati
219 dividuals deposited reserves over winter and catabolized reserves over summer, mainly because regulat
224 f exogenous substrate, oral bacteria readily catabolize salivary protein and generate metabolic profi
226 e double mutant acx1-1 acx2-1 were unable to catabolize seed storage lipid, and accumulated long-chai
227 sult in hypercolonization and the ability to catabolize serine represents a positive physiological tr
229 is a mammalian integral membrane enzyme that catabolizes several neuromodulatory fatty acid amides, i
230 ite observations that COMT is estrogenically catabolized, sex differences in its prefrontal repercuss
236 6390 confirmed that acetate was incompletely catabolized, suggesting that the ability to catabolize a
237 eaminase (TD), act in the M. sexta midgut to catabolize the essential amino acids Arg and Thr, respec
238 expression of 15 genes encoding enzymes that catabolize the last half of the cholesterol molecule, re
239 although several classes of enzymes that can catabolize the latter two have been characterized, studi
240 major role of KatG in MTB pathogenesis is to catabolize the peroxides generated by the phagocyte NADP
241 lasts during early seed development and then catabolize the photosynthetic machinery during seed matu
242 holine kinase-alpha (CHKA), the enzymes that catabolize the products of EDI3 to determine which downs
247 enzyme that inhibits T-cell proliferation by catabolizing the essential amino acid tryptophan (Trp) i
250 xtracellular homopolymers of fructose and to catabolize these types of polymers is suspected to be a
252 13 lineage 2, suggesting that the ability to catabolize this carbon source has been negatively select
256 -hydroxyacid derived from 4-HNE) is primarly catabolized through a pathway that phosphorylates the C-
258 rts glutamine to glutamate, which is further catabolized through the tricarboxylic acid cycle for the
261 ate (epsilon-Ap(4)), respectively, which are catabolized to 1,N(6)-ethenoadenosine (epsilon-Ado) as t
263 vate or [(14)C]threonine, either of which is catabolized to [(14)C]acetyl-CoA in the mitochondrion.
265 lization, ADCs with noncleavable linkers are catabolized to amino acid-linker-warheads within the lys
267 H]GlcN, it was shown that these residues are catabolized to generate radiolabeled products that are u
268 rovide a better understanding of how DMSP is catabolized to generate the important climate-active gas
273 te, and acetoin, suggesting that glucose was catabolized to pyruvate that was then catabolized via th
274 n tissue samples, (3)H-DHT was predominantly catabolized to the 5alpha-androstane-3alpha,17beta-diol
275 de 2,4-dichlorophenoxybutyric acid, which is catabolized to the auxin 2,4-dichlorophenoxyacetic acid
276 the ruminant nor the normal rumen flora can catabolize tricarballylate to ameliorate its toxic effec
279 oxygenase (IDO) and arginase 1 (ARG1), which catabolize Trp and Arg, respectively, respond to inflamm
281 many tumors including gliomas constitutively catabolize tryptophan, it is unclear whether quinolinic
285 a component of the kynurenine pathway, which catabolizes tryptophan in mammals and certain bacteria.
286 n in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstrea
287 We have identified tryptophanase (which catabolizes tryptophan to pyruvate and indole) as an Rcd
290 ver, certain tumor types that are capable of catabolizing tryptophan but are largely IDO-negative.
292 acids in pectin and xylan, respectively, are catabolized via committed metabolic pathways to supply c
296 se was catabolized to pyruvate that was then catabolized via the lactate dehydrogenase, pyruvate form
297 anoic acid (4,8-DHNA), which is subsequently catabolized via two parallel pathways we previously repo
298 Triglyceride-rich lipid droplets (LDs) are catabolized with high efficiency in hepatocytes to suppl
299 , as a branched-chain amino acid, Leu can be catabolized within muscle, thus posing the possibility t