ライフサイエンスコーパス: catalyse

1 en protein sequence and cyclisation reaction catalysed.

2 e to other small-molecule and polymerization catalyses.

3 new feature to exploit in other homogeneous catalyses.

4 However, although enzyme-catalysed [6+4] cycloadditions have been proposed(10-12)

5 This type of pericyclase catalyses [6+4] and [4+2] cycloadditions through a singl

6 ein enzyme cofactors that, in principle, can catalyse a chemical reaction.

7 Nature uses multinuclear metal clusters to catalyse a number of important multielectron redox react

8 Here we demonstrate a group of enzymes that catalyse a pericyclic [6+4] cycloaddition, which is a cr

9 Redox active metalloenzymes catalyse a range of biochemical processes essential for

10 yme protochlorophyllide oxidoreductase (POR) catalyses a light-dependent step in chlorophyll biosynth

11 e leader-side CRISPR repeat, and finally, it catalyses a nucleophilic attack that connects one strand

12 e, previously unknown in biology; the second catalyses a stereoselective hetero-Diels-Alder reaction.

13 mechanisms and obviating the need for metal-catalysed abiotic reductive aminations.

14 hesome complexes that activate pathways that catalyse actin polymerization.

15 nction signalling complexes (adhesomes) that catalyse actin polymerization.

16 n the remarkable efficiency of the ruthenium-catalysed alkene-alkyne coupling reaction between readil

17 Transition metal-catalysed allylic functionalization reactions have been

18 Transition metal-catalysed allylic functionalization reactions involving

19 that catalyse distinct reactions: one group catalyses an Alder-ene reaction that was, to our knowled

20 ing drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to o

21 erase (MaDA), from Morus cell cultures, that catalyses an intermolecular [4+2] cycloaddition to produ

22 yme from the biosynthesis of streptozotocin, catalyses an oxidative rearrangement of the guanidine gr

23 plinary public-private partnership that will catalyse and promote HIV cure research through diverse s

24 onstrate that a polarity-reversed photoredox-catalysed arene deoxyfluorination operating via cation r

25 recent progress in characterizing the enzyme-catalysed assembly of the H-cluster, including informati

26 Here we report a rhodium-catalysed asymmetric Suzuki-Miyaura reaction with import

27 alkyne has found broad utility via the Cu(I)-catalysed azide-alkyne cycloaddition 'click' reaction(18

28 nto peptide oligomers via solid-phase copper-catalysed azide-alkyne cycloaddition (SP-CuAAC) click re

29 inear splicing (typically on short exons) or catalyses back-splicing to generate circular RNA (on lon

30 es proposed in this work extend to palladium-catalysed benzylic substitution, demonstrating the gener

31 Here we report a Pd-catalysed beta-C(sp(3))-H lactonization of aliphatic aci

32 The iridium-catalysed borylation of aromatic C-H bonds has become th

33 ides to locate complementary transcripts and catalyse both sequence-specific cis- and non-specific tr

34 ingle ER-localised Fic protein, FICD (HYPE), catalyses both AMPylation and deAMPylation of BiP.

35 s a eukaryotic DNA base modification that is catalysed by a divergent TET homologue and unexpectedly

36 ation of tryptophan to N-formylkynurenine is catalysed by a family of dioxygenases, including indolea

37 ventional heteroatom and carbon nucleophiles catalysed by a metallacyclic iridium catalyst.

38 Triacylglycerol synthesis is catalysed by acyl-CoA diacylglycerol acyltransferase (DG

39 lation is a reversible chemical modification catalysed by ADP-ribosyltransferases such as PARPs that

40 minal alkenes that does not occur naturally, catalysed by an 'ene' reductase using readily available

41 dration of n-octanaloxime to n-octanenitrile catalysed by an aldoxime dehydratase (OxdB) overexpresse

42 s suitable for various ketone substrates, is catalysed by an iridium/phosphine combination and is pro

43 de novo phosphatidylcholine biosynthesis is catalysed by CTP: phosphocholine cytidylyltransferase (P

44 reased rate of peptidyl-prolyl isomerisation catalysed by CypD.

45 try level, yet appear almost reversible when catalysed by enzymes.

46 e show that increased transamination, mainly catalysed by GOT1, leads to increased levels of 2-hydrox

47 mplexed with two substrate peptides that are catalysed by human TPST1 with significantly different ef

48 iosynthesis in Mycobacterium tuberculosis is catalysed by mycolyl reductase encoded by the Rv2509 gen

49 y active gold site for reactions known to be catalysed by oxidized gold species.

50 osphatidylcholine to choline was found to be catalysed by phospholipase D enzymes from diverse member

51 seful insights into the cyclisation reaction catalysed by pinene synthase were obtained, including th

52 oly(ADP-ribosyl)ation (PARylation) is mainly catalysed by poly-ADP-ribose polymerase 1 (PARP1), whose

53 s to synthesize omega-3 esters from chia oil catalysed by polyethylene glycol-modified lipases using

54 protein increases the rate of ATP hydrolysis catalysed by RecN during the DNA pairing reaction.

55 00A4 to the NM myosin heavy chain, which was catalysed by RhoA GTPase via the RhoA-binding protein, r

56 Externalization of this phospholipid is catalysed by scramblase enzymes, several of which are ac

57 e paternal pronucleus after fertilization is catalysed by SUV39H2 and that pericentromeric RNAs inhib

58 ns into the bacterial outer membrane (OM) is catalysed by the beta-barrel assembly machinery (BAM).

59 h is essential in eukaryotes and archaea, is catalysed by the Box C/D RNP complex in an RNA-guided ma

60 he second messenger cAMP, whose synthesis is catalysed by the enzyme adenylyl cyclase 5 (AC5), which

61 position U54 of tRNAs where modification is catalysed by the methyltransferase Trm2.

62 It is catalysed by the RecA family of ATPases, which form a he

63 e research of a generation of ecologists was catalysed by the recognition that the number and identit

64 viral genetic material into the host genome, catalysed by the retroviral integrase (IN) enzyme.

65 ividual ribosomal subunits-a process that is catalysed by this universally conserved initiation facto

66 of post-translational protein modifications catalysed by TPSTs.

67 pathway featuring dehydration processes and catalysed by unusual condensation domains.

68 e-promoted alpha-hydroxyketone rearrangement catalysed by vanadium-dependent haloperoxidases to accou

69 Such reactions are often catalysed by visible-light-absorbing organic molecules o

70 -derived cytosine base editors (DdCBEs) that catalyse C*G-to-T*A conversions in human mtDNA with high

71 y candidate cytochrome P450 enzymes that may catalyse C-21beta oxidation.

72 A practical and selective metal-catalysed C(sp(3))-H activation facilitated by the terti

73 overview of the recent development in copper-catalysed C-C, C-N, C-B, C-Si and C-F bond-forming react

74 Transition metal-catalysed C-H functionalization and decarboxylative coup

75 plex activates H2 under mild conditions, and catalyses C-H hydride abstraction plus H2 generation fro

76 We show how MT enzymes can utilise cxSAM to catalyse carboxymethylation of tetrahydroisoquinoline (T

77 selected fit with induced fit mechanisms to catalyse collagen unwinding prior to cleavage of individ

78 n associated mechanism concerning Lewis base-catalysed, complexation-induced HAT (LBCI-HAT).

79 This work shows how enzymes are able to catalyse concerted pericyclic reactions involving ambimo

80 electron reduction of CO2 for the photoredox-catalysed continuous flow synthesis of alpha-amino acids

81 The ATPase-catalysed conversion of ATP to ADP is a fundamental proc

82 nstrate that MavC is a transglutaminase that catalyses covalent linkage of ubiquitin to Lys(92) and L

83 Enzymes that catalyse CpG methylation in DNA, including the DNA methy

84 Whereas advances in the related field of Pd-catalysed cross-coupling have been driven by ligand desi

85 Transition metal-catalysed cross-coupling reactions are widely used for c

86 Examples of stereospecific, Pd-catalysed cross-coupling reactions have been reported fo

87 Transition-metal-catalysed cross-coupling reactions have been widely used

88 Advances in Pd-catalysed cross-coupling reactions have facilitated the

89 Transition-metal-catalysed cross-coupling reactions, particularly those m

90 alternative to traditional transition-metal-catalysed cross-coupling reactions.

91 ally impact the stereochemical outcome of Pd-catalysed cross-coupling reactions.

92 ometallic nucleophiles in stereospecific, Pd-catalysed cross-coupling reactions.

93 applications of transition metal/photoredox-catalysed cross-coupling, thermal/photosensitized radica

94 ose a class of phosphines that enable the Ni-catalysed Csp(3) Suzuki coupling of acetals with boronic

95 In this context, so-called internally catalysed DCC platforms have started to receive more int

96 ggest a pathway that involves an uncommon Pd-catalysed dearomatization of the benzyl moiety followed

97 In honey it is likely the base-catalysed decomposition predominates with water as catal

98 ndo-beta(1 -> 4)-mannanases (endomannanases) catalyse degradation of beta-mannans, an abundant class

99 established methods such as transition metal-catalysed dehydrocoupling, which only yield P-monosubsti

100 polymeric polyphenols, before and after acid-catalysed depolymerisation in the presence of a nucleoph

101 s homologue from the paraherquamide pathway) catalyse diastereo- and enantioselective cyclization in

102 demonstrate that cucurbit[7]uril (CB[7]) can catalyse Diels-Alder reactions for a number of substitut

103 Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin modifications to enforce gen

104 f two homologous groups of pericyclases that catalyse distinct reactions: one group catalyses an Alde

105 ocesses, the fundamental mechanism of SAMHD1-catalysed dNTP hydrolysis remained unknown.

106 cognate RDFs to create single proteins that catalyse efficient attL x attR recombination in vivo and

107 eading step it is necessary to visualize GTP-catalysed elongation, which has remained a challenge(2-4

108 Here we report a Pd(II)-catalysed enantioselective alpha-C-H coupling of a wide

109 stereocentres by forging a C-C bond via a Pd-catalysed enantioselective Heck reaction of acyclic alke

110 A bifunctional iminophosphorane (BIMP)-catalysed enantioselective synthesis of alpha,beta-unsat

111 xpected zwitterionic intermediate where MalC catalyses enantioselective cycloaddition as a bifunction

112 by reduced expression of GAPDH encoding the catalysing enzyme for this step.

113 gh the merger of light-driven, decatungstate-catalysed hydrogen atom transfer and copper catalysis.

114 The MBIS film was prepared by acid-catalysed hydrolysis/condensation of the sample solution

115 AspH catalyses hydroxylation of asparaginyl- and aspartyl-res

116 bacteria, lipid modification of proteins is catalysed in a three-step pathway.

117 terconversion of phosphoglycerate isomers is catalysed in numerous pathogenic microorganisms by a cof

118 lone Diels-Alderase has been demonstrated to catalyse intermolecular Diels-Alder transformations.

119 ere we report a cationic iridium system that catalyses intermolecular hydroamination of a range of un

120 phiphilic imine dissolved in chloroform that catalyses its own formation by bringing together a hydro

121 HOIL-1 also catalyses its own monoubiquitylation in cells and most p

122 tation serve to activate surface adsorbates, catalysing key elementary processes (namely formate conv

123 Sortase A-catalysed ligation also obviously improved Tms and produ

124 he formation of NVOFAs was related to lipase catalysed lipid hydrolysis and the formation of volatile

125 ogen Shewanella oneidensis can control metal-catalysed living radical polymerizations under apparent

126 Although the mammalian enzymes that catalyse m5U formation are yet to be identified via expe

127 ity that is orthogonal to conventional metal-catalysed manifolds, diverse aryl and heteroaryl partner

128 However, enzymes likely catalysed many different reactions already in the last u

129 ing confirmed the existence of acid and base-catalysed mechanisms for dimer decomposition and the str

130 ling mechanistic uncertainties in human P450-catalysed metabolism of the immunomodulatory drug leflun

131 port a versatile and rapid metallaphotoredox-catalysed method for late-stage installation of both tri

132 We also show that our tBuOK catalysed methodology is general for the heterodehydroco

133 dried milk can be used directly in alkaline-catalysed methylation, whereas direct transesterificatio

134 PRC2 is a histone-modifying complex that catalyses methylation of lysine 27 of histone H3 (H3K27m

135 of acetate release, it was shown that AnCDA catalyses mono-deacetylation of (GlcNAc)2 and full deace

136 stingly, we have identified two enzymes that catalyse NEIL1 polyubiquitylation, Mcl-1 ubiquitin ligas

137 alth systems' progress toward new goals, and catalysing new forms of civil society engagement in the

138 ave developed iron sulfide nanoclusters that catalyse nitric oxide generation from benign sodium nitr

139 rucial for rhizobial enzyme nitrogenase that catalyses nitrogen fixation, but the SM iron transporter

140 yosin II in airway SM at the cell cortex and catalysed NM myosin filament assembly.

141 n tension development in airway SM tissue by catalysing NM myosin filament assembly, and that the int

142 n the regulation of airway SM contraction by catalysing NM myosin filament assembly.

143 Palladium-catalysed non-directed C-H activation could potentially

144 the occurrence and formation of peroxygenase catalysed non-volatile oxidised fatty acids (NVOFAs), es

145 io entities at anode to produce bioenergy by catalysing organic substrates while some systems convert

146 ration of red-fluorescent resorufin from LPO catalysed oxidation of Amplex(R) Red (1-(3,7-dihydroxyph

147 The hydrogen peroxide generated by XO catalysed oxidation of hypoxanthine, and PAO catalysed o

148 e intermediacy of Co(IV)-O species in cobalt-catalysed oxidation of organic substrates as well as in

149 catalysed oxidation of hypoxanthine, and PAO catalysed oxidation of spermine, was coupled to horserad

150 Here, we demonstrate copper-catalysed oxidative cross coupling of benzylic C-H bonds

151 Semicarbazide-sensitive amine oxidase (SSAO) catalyses oxidative deamination of primary amines.

152 (PHD 1, 2 and 3) to signal oxygen levels by catalysing oxygen regulated prolyl hydroxylation of the

153 ed as such in either abiotic or proto-enzyme-catalysed pathways to DNA, as demonstrated by its conver

154 overed pericyclases-a family of enzymes that catalyse pericyclic reactions(1).

155 hile in-line with the P(alpha)-O(5') bond to catalyse phosphoester bond hydrolysis.

156 The family of bacterial SidE enzymes catalyses phosphoribosyl-linked serine ubiquitination an

157 HSP90 is a substrate for casein kinase 1.2-catalysed phosphorylation in vitro.

158 ubixanthin and (all-E)-lycopene using iodine-catalysed photoisomerisation showed that the (5'Z)-isome

159 hypothesized to be the Na(+) /Pi symporters catalysing Pi uptake in chlorophytes, whereas PHOSPHATE

160 The key reaction is a palladium-catalysed polyenyne cycloisomerization that not only tol

161 urrently achievable only in transition-metal-catalysed processes and requires halogen- or boron-conta

162 that are distinct from those formed by acid-catalysed processes.

163 We cannot exclude PHD-catalysed prolyl hydroxylation occurring under condition

164 These efforts need to be catalysed, promoted and fostered through international c

165 ology depends on cullin-RING E3 ligase (CRL)-catalysed protein ubiquitylation(1), which is tightly co

166 Palmitoyltransferase (PAT) catalyses protein S-palmitoylation which adds 16-carbon

167 Here, we report a Pd(II)-catalysed protocol that appends arene feedstocks to tert

168 hat contrast with those of established metal-catalysed protocols.

169 tent complex formed via an initiation-factor-catalysed reaction has precluded an understanding of the

170 nt, and mechanisms by which pericyclases can catalyse reactions are of major interest(1).

171 Harnessing these cooperative interactions to catalyse reactions in synthetic systems, however, remain

172 Many enzymes catalyse reactions that proceed through covalent acyl-en

173 elease approach in which glycosyltransferase-catalysed reactions are performed in solution and produc

174 erization, wherein a series of enzymatically catalysed reactions is employed to generate secondary me

175 ngs are likely to be relevant to all RING E3 catalysed reactions ligating ubiquitin and other ubiquit

176 deoxygenation, oxidation, reforming and acid-catalysed reactions, spanning a broad spectrum of substr

177 exploit a potentially large number of enzyme-catalysed reactions.

178 Here, we demonstrate that these enzymes can catalyse redox-neutral radical cyclizations to produce e

179 Biologically catalysed redox reactions involving sulfate, sulfide and

180 of three known light-dependent enzymes(4,5), catalyses reduction of the photosensitizer and substrate

181 anism, we recently found that EREDs can also catalyse reductive dehalogenations and cyclizations via

182 To catalyse reform, we outline recommendations for (1) skil

183 is demonstrated by the finding that Fml1 can catalyse regressed fork restoration in vitro.

184 cols for fixation, nucleic acid staining and catalysed reporter deposition fluorescence in situ hybri

185 oal we describe a new bacteria-mediated iron-catalysed reversible deactivation radical polymerisation

186 Thus, EGFR or HER2 can catalyse rigidity sensing after associating with nascent

187 ted nuclease-deficient CRISPR-Cas systems to catalyse RNA-guided integration of mobile genetic elemen

188 erstanding of the optical properties of self-catalysed (SC), zinc blende (ZB) dominant, nanowires (NW

189 iew the rapidly expanding field of ruthenium catalysed sigma-activation as a tool in the selective me

190 The Varkud satellite ribozyme catalyses site-specific RNA cleavage and ligation, and s

191 ms of human copper chaperone for SOD1 (hCCS)-catalysed SOD1 activation based on crystal structures of

192 In this way, hCCS-catalysed SOD1 maturation is finessed to minimise copper

193 and define paracrystalline surfaces able to catalyse specific enantioselective chemical reactions.

194 onine (SAM)-dependent enzyme, LepI, that can catalyse stereoselective dehydration followed by three p

195 cal characterization has shown that LepI can catalyse stereoselective dehydration to yield a reactive

196 ptic filaments form, search for homology and catalyse strand exchange is poorly understood.

197 Here, we report a palladium-catalysed strategy that confers the formed palladium dif

198 e (pyro)phosphate binding site are unable to catalyse subsequent Friedel-Crafts alkylation of the fla

199 Candida antarctica lipase B-catalysed synthesis of lipophilic esters of polydatin wa

200 irst step towards a general transition metal catalysed synthesis of tetraarylmethanes.

201 ons of MaDA with the diene and dienophile to catalyse the [4+2] cycloaddition.

202 cyl-tRNA synthetases (aaRSs), which not only catalyse the attachment of cognate amino acids to their

203 cosylation, a series of glycosyltransferases catalyse the biosynthesis of a dolichylpyrophosphate-lin

204 ses represent a large family of enzymes that catalyse the biosynthesis of oligosaccharides, polysacch

205 Escherichia coli (E. coli) was engineered to catalyse the cleavage of 2'-FL into L-fucose and lactose

206 gap between military and civilian actors to catalyse the contributions of all participants to enhanc

207 2 and ME3) are oxidative decarboxylases that catalyse the conversion of malate to pyruvate and are es

208 viding regulatory and economic incentives to catalyse the development of specific therapies.

209 ilaments, which search for homology and then catalyse the exchange of the complementary strand, formi

210 acylglycerol acyltransferases (DGAT) 1 and 2 catalyse the final step in triacylglycerol (TAG) synthes

211 tase (MCR) has been originally identified to catalyse the final step of the methanogenesis pathway.

212 Centrosomes catalyse the formation of microtubules needed to assembl

213 This Minireview focuses on enzymes which catalyse the insertion of an oxygen atom into the substr

214 (gamma-TuRCs), multi-protein complexes that catalyse the kinetically unfavourable formation of new m

215 ine (SAM)-dependent methyltransferases (MTs) catalyse the methylation of a vast array of small metabo

216 hment of multidisciplinary collaborations to catalyse the opportunities offered by current and future

217 NAD(P)H oxidase 4 (NOX4), an enzyme known to catalyse the oxidation of NAD(P)H, is upregulated when p

218 Understanding how materials that catalyse the oxygen evolution reaction (OER) function is

219 Protein kinases catalyse the phosphorylation of target proteins, control

220 deploy molecular oxygen as a co-substrate to catalyse the post-translational hydroxylation of specifi

221 synthase from Thalictrum flavum (TfNCS) can catalyse the PSR between dopamine and unactivated ketone

222 glue degraders act substoichiometrically to catalyse the rapid depletion of previously inaccessible

223 Here we report f-block complexes that can catalyse the reduction and functionalization of molecula

224 Eukaryotic box C/D small nucleolar (sno)RNPs catalyse the site-specific 2-O-methylation of ribosomal

225 The chloride ions and the AuNPs present catalyse the starch-amylase reaction on the PANI surface

226 A single PdNP-loaded gel bead can catalyse the Suzuki-Miyaura reaction, constituting a sim

227 On binding to DNA, cGAS is activated to catalyse the synthesis of cyclic GMP-AMP (cGAMP) from GT

228 nzyme A:cholesterol acyltransferases (ACATs) catalyse the transfer of an acyl group from acyl-coenzym

229 al analyses determine that these two enzymes catalyse the transfer of PEA from the donor PE lipid sub

230 One of the new enzymes catalysed the cyclisation of geranylgeranyl diphosphate

231 The composite material catalysed the degradation of Rhodamine B at over double

232 invasions endured by organisms for eons have catalysed the evolution of gene-regulatory networks.

233 This electrode catalysed the oxidation of both glycerol and glyceraldeh

234 ctor fusion (Integrase-RDF) that efficiently catalysed the reverse attR x attL recombination.

235 The COVID-19 pandemic has catalysed the sudden adoption of telemedicine in the man

236 Ubiquitous tyrosinase catalyses the aerobic oxidation of phenols to catechols

237 ase (ACLY) is a central metabolic enzyme and catalyses the ATP-dependent conversion of citrate and co

238 ng enzyme (CMD1) that is a TET homologue and catalyses the conjugation of a glyceryl moiety to the me

239 It catalyses the conversion of 2-hydroxyacetophenone to (S)

240 nsists of a self-labelling enzyme tag, which catalyses the covalent linking of exogenously supplement

241 Serine palmitoyltransferase (SPT) catalyses the de novo biosynthesis of sphingolipids but

242 n target, thymidylate synthase (TYMS), which catalyses the de novo pathway for production of deoxythy

243 terbacterial toxin, which we name DddA, that catalyses the deamination of cytidines within dsDNA.

244 ma-aminobutyric acid (GABA) metabolism as it catalyses the decarboxylation of glutamic acid to form G

245 ession of fumC, which encodes an enzyme that catalyses the degradatin of fumarate, an inhibitor of gl

246 MoHMT1 catalyses the di-methylation of arginine 247, 251, 261 a

247 cy of NSD1, a histone methyltransferase that catalyses the dimethylation of histone H3 at K36 (H3K36m

248 It catalyses the dissimilatory oxidation of iron, sulfur, a

249 The enzyme leukotriene A4 hydrolase (LTA4H) catalyses the distal step in LTB4 synthesis and hence in

250 Initial studies indicated SOR catalyses the essential first step in oxidation of eleme

251 cy of glucose-6-phosphatase, an enzyme which catalyses the final step of gluconeogenesis and glycogen

252 radation of the essential enzyme MurA, which catalyses the first committed step in PG biosynthesis.

253 osphate- and magnesium-dependent enzyme that catalyses the first step in the biosynthesis of branched

254 Cohesin catalyses the folding of the genome into loops that are

255 mplex with RNMT-activating miniprotein (RAM) catalyses the formation of a N7-methylated guanosine cap

256 HOIP catalyses the formation of Met1-linked ubiquitin oligome

257 Microbial transglutaminase (mTG) catalyses the formation of protein crosslinks, deamidati

258 lmethionine (SAM)-dependent pericyclase that catalyses the formation of the 2-pyridone natural produc

259 is the only known E3 ubiquitin ligase which catalyses the generation of linear ubiquitin linkages de

260 of Abeta) fibrils, fibrillar alpha-synuclein catalyses the heterogeneous nucleation of Abeta42 aggreg

261 CD38 is an enzyme that catalyses the hydrolysis of nicotinamide adenine dinucle

262 aspartate/asparagine-beta-hydroxylase (AspH) catalyses the hydroxylation of Asp/Asn-residues in epide

263 nd inactive 'open' conformations, and TRIP13 catalyses the inactivating conformational change, thereb

264 Haem-copper oxidase (HCO) catalyses the natural reduction of oxygen to water using

265 s benzoate and cyclohexane-1-carboxylate and catalyses the novel synthesis of benzoate and cyclohexan

266 It catalyses the O-GlcNAc posttranslational modification of

267 (6) f occurs via the quinol (Q) cycle, which catalyses the oxidation of plastoquinol (PQH(2)) and the

268 Squalene monooxygenase catalyses the oxidation of squalene to 2,3-oxidosqualene

269 hat mediate lipid peroxidation, whereas FSP1 catalyses the regeneration of CoQ(10) using NAD(P)H.

270 ntified a non-canonical cytochrome P450 that catalyses the remarkable ring expansion reaction that is

271 Carbonic anhydrase VI (CA6) catalyses the reversible hydration of carbon dioxide in

272 Lysophosphatidate acyltransferase (LPAAT) catalyses the second step of the Kennedy pathway for tri

273 d previously to reduce CO(2) to primarily CO-catalyses the six-electron reduction of CO(2) to methano

274 It catalyses the synthesis of cyclic GMP-AMP (cGAMP)(9-12),

275 (cGAS) is a double-stranded DNA sensor that catalyses the synthesis of the cyclic dinucleotide cycli

276 Apolipoprotein N-acyl transferase (Lnt) catalyses the third step in this pathway, whereby it tra

277 It catalyses the transformation of the superoxide anion (O2

278 sequently, this suggests that lithium may be catalysing the activity of endogenous mechanisms that pr

279 on in airway SM and regulates contraction by catalysing the assembly of integrin-associated adhesome

280 By catalysing the breakdown of beta-1, 4-glycosidic linkage

281 mononuclear non-haem iron enzyme capable of catalysing the C-S bond formation and sulfoxidation, her

282 y known as the first enzymes of translation, catalysing the conjugation of amino acids to cognate tRN

283 ylase enzyme (HDC), which is responsible for catalysing the decarboxylation of histidine to histamine

284 lay, optimising therapeutic trial design and catalysing the development of disease-modifying therapy.

285 were the key players for methane oxidation, catalysing the first reaction step to methanol.

286 eoside-5'-triphosphate (dNTP) homeostasis by catalysing the hydrolysis of dNTPs into 2'-deoxynucleosi

287 blish that the PPKs are directly involved in catalysing the photoactivated-phy-induced phosphorylatio

288 Catalysing the reduction of oxygen in acidic media is a

289 Despite catalysing the same reaction and being present in the sa

290 oride salts are significantly more active in catalysing the SuFEx reaction compared to organosuperbas

291 MBOAT family recognize their substrates and catalyse their reactions is unknown.

292 eless, the microorganisms and reactions that catalyse this process have to date remained unknown(8).

293 DSR genes from bacteria, has been proven to catalyse this reaction.

294 (ADP-ribosyl)ation and the major enzyme that catalyses this reaction, poly(ADP-ribose) polymerase 1 (

295 ide acquisition steps in this pathway can be catalysed through a direct interaction with the copper c

296 Through microbial transglutaminase-catalysed transamidation of gluten proteins using ethyla

297 tionarily conserved Elongator complex, which catalyses translational elongation through tRNA modifica

298 dimethyl sulfoxide reductase (DMSOR) family catalyse two-electron redox reactions pivotal to the dis

299 scher indole synthesis, we report an iridium-catalysed tyrosinase-like approach to catechols, employi

300 However, how CRLs catalyse ubiquitylation, and the basis of NEDD8 activati