コーパス検索結果 (１語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 -cadherin and stabilizes the E-cadherin-beta-catenin complex.
2 ting an E3 ligase, Smurf2, to the Smad7/beta-catenin complex.
3 tion of alpha-catenin with the DeltaEXD-beta-catenin complex.
4 fied in immunoprecipitates of the N-cadherin.catenin complex.
5 might involve the disruption of the cadherin/catenin complex.
6 iation of Erbin with the junctional cadherin-catenin complex.
7 ars to be independent of the E-cadherin-beta-catenin complex.
8 ell adhesion and interacts with the cadherin-catenin complex.
9 her and how Wnt signaling regulates the beta-catenin complex.
10 iling to recruit GSK-3beta into the PS1-beta-catenin complex.
11 rs and plays a distinct role in the cadherin-catenin complex.
12 ty inhibits formation of the E-cadherin-beta-catenin complex.
13 dherin or in the composition of the cadherin-catenin complex.
14 amily (LAR-PTP) associates with the cadherin-catenin complex.
15 t polarization depend on the N-cadherin-beta-catenin complex.
16 ermeability due to modulation of VE-cadherin/catenin complex.
17 mouse brain and colocalizes to the cadherin-catenin complex.
18 all levels of alphaE-catenin or the cadherin-catenin complex.
19 here it colocalizes with the E-cadherin/beta-catenin complex.
20 transcriptional activation of the Lef-1-beta-catenin complex.
21 eins, but is not a core part of the cadherin-catenin complex.
22 than when it cannot bind the E-cadherin-beta-catenin complex.
23 catenin complexes but not from TRbetaPV-beta-catenin complexes.
24 or that bridges gamma-secretase and cadherin-catenin complexes.
25 by dephosphorylating components of cadherin-catenin complexes.
26 dulate the phosphorylation state of cadherin/catenin complexes.
27 er 1, is also directly regulated by TCF-beta-catenin complexes.
28 blot analysis of immunoprecipitated cadherin/catenin complexes.
29 n is necessary for the formation of PS1/beta-catenin complexes.
30 iation between caspase-8 and E-cadherin:beta-catenin complexes.
31 e designed peptide preserved native APC-beta-catenin complexes.
32 lines greatly increased the stability of APC-catenin complexes.
33 adhere to an adjacent myofiber via cadherin-catenin complexes.
34 of adherens junctions destabilizes cadherin-catenin complexes.
35 tivates target gene expression via Lef1-beta-catenin complexes.
36 e activation of target genes by Tcf/Lef-beta-catenin complexes.
37 lethal in embryos with compromised cadherin-catenin complexes.
38 Wnt target gene and is activated by TCF-beta-catenin complexes.
40 o axin/glycogen synthase kinase 3(GSK3)/beta-catenin complexes (AGbetaC) as Wnt decreases Dishevelled
42 present strong evidence that in the cadherin-catenin complex alpha-catenin contributes to the binding
45 uggest that the linkage between the cadherin-catenin complex and actin filaments is more dynamic than
47 PLIN establishes a link between the cadherin.catenin complex and actin that is independent of actomyo
48 o require a stable link between the cadherin-catenin complex and actin that is mediated by alpha-cate
49 ession of the membrane-associated E-cadherin/catenin complex and at a rate higher than those observed
50 hat regulate the levels of the core cadherin-catenin complex and coordinate cadherin-mediated cell-ce
51 lted in dissociation of the VE-cadherin/p120-catenin complex and disassembly of adherens and tight ju
52 em stimulates disassembly of the E-cadherin- catenin complex and increases the cytosolic pool of beta
53 nctions critically depend on the VE-cadherin/catenin complex and its interaction with the actin filam
55 e evidence that JNK binds to E-cadherin/beta-catenin complex and phosphorylates beta-catenin at serin
56 embrane localization of VE-cadherin and beta-catenin complex and promoting their barrier function, an
58 ell adhesion mediated by the E-cadherin/beta-catenin complex and that shibire, the Drosophila homolog
59 causes the breakdown of the N-cadherin/beta-catenin complex and that the organism can sequester beta
60 years, and the link between the VE-cadherin.catenin complex and the actin cytoskeleton remains uncle
63 a quaternary complex comprising the cadherin-catenin complex and the vinculin head region, which cann
64 nin signaling increased binding of Tcf4/beta-catenin complex and upregulated its enhancer function.
65 , interacts with the classical cadherin-beta-catenin complex and with F-actin, but its precise role i
66 gulator of Wnt signaling, is present in beta-catenin complexes and activated in Wnt-signaling cells.
68 iation of vascular endothelial cadherin/beta-catenin complexes and resultant endothelial barrier disr
69 -cadherin/gamma-catenin from N-cadherin/beta-catenin complexes and the identification of multiple mem
70 oresponsive link between the E-cadherin.beta-catenin complexes and the underlying actin cytoskeleton.
71 ated that S100A7 is associated with the beta-catenin complex, and inhibits beta-catenin signaling by
72 of dendritic targeting of the cadherin-beta-catenin complex, and reduction in the amplitude and freq
73 tion with beta-catenin and the cadherin.beta-catenin complex, and the effect of the alpha-catenin act
74 ha-actinin, and vinculin from the E-cadherin-catenin complex, and this coincided with a robust phosph
75 tes cytoskeletal association of the cadherin/catenin complexes, and increases Ca(2+)-dependent cell-c
76 ement membrane and re-established E-cadherin-catenin complexes, and re-organized their cytoskeletons.
77 generate phospho-Smad2 (p-Smad2)-pY654-beta-catenin complexes, and up-regulate mesenchymal target ge
78 llular adhesions formed through the cadherin-catenin complex are important determinants of proper tis
79 sing anti-proN-cadherin showed that cadherin-catenin complexes are assembled prior to localization at
81 binding protein that binds the cadherin.beta-catenin complex as a monomer and whose dimerization pote
82 These data suggest that a core N-cadherin-catenin complex assembles in the endoplasmic reticulum o
86 on of IQGAP1 with components of the cadherin-catenin complex at cell-cell junctions, resulting in imp
87 es the recruitment of PI3K to the E-cadherin-catenin complex at the plasma membrane of human keratino
88 toplasmic tail (CT), loss of E-cadherin/beta-catenin complexes at the adherens junctions (AJs), intra
89 tes interrupts and destabilizes the cadherin-catenin complexes at the cell membrane leading to nuclea
90 a full but inactive complement of E-cadherin-catenin complexes at the cell surface, but they can be t
92 nal model of the cadherin.beta-catenin.alpha-catenin complex based on these new structural data sugge
97 itation analysis determined that the AR/beta-catenin complex binds to the proximal region of the pros
99 little effect on formation of the N-cadherin-catenin complex but instead resulted in increased N-cadh
100 uelch reporter gene activation by LEF-1-beta-catenin complexes but not activation by the transcriptio
101 eta-catenin was dissociated from TRbeta-beta-catenin complexes but not from TRbetaPV-beta-catenin com
102 ecruitment of actin networks to the cadherin-catenin complex, but how such networks are subsequently
104 subjected to mechanical force, the cadherin*catenin complex can tightly link to F-actin through alph
107 sical cadherins form a multiprotein cadherin-catenin complex (CCC) that constitutes the major structu
109 s part of the E-cadherin-beta-catenin-alphaE-catenin complex (CCC), mammalian alphaE-catenin binds F-
111 ow increased mobility of ABD in the cadherin-catenin complex, compared to the a-catenin homodimer.
112 f cell type or glycosylation state, although catenin complex composition varied, showing enriched alp
115 enes through the increased formation of beta-catenin complexes containing TCF transcription factors.
116 dherin-beta-catenin-alphaE-catenin (cadherin-catenin) complex couples the cytoskeletons of neighborin
117 k by which vinculin and afadin tune cadherin-catenin complex-cytoskeleton coupling to support AJ func
118 yers and disrupted membrane VE-cadherin/beta-catenin complexes, decreased beta-catenin phosphorylatio
120 ent VE-cadherin phosphorylation, VE-cadherin/catenin complex destabilization, and subsequent VE-cadhe
121 ine phosphatases associate with the cadherin-catenin complex, directly regulating the phosphorylation
122 timulation, Mfn2 is sulfenylated, the Mfn2/B-catenin complex disassociates from the AJs and Mfn2 accu
123 sed conformation, leading to the VE-cadherin/catenin complex disruption to enhance endothelial permea
124 hosphorylation is normal, p-Smad2-pY654-beta-catenin complexes do not form in the absence of alpha3 o
126 (a survival-promoting component of cadherin-catenin complexes), down-regulation of 51C (an inositol
128 ies at the free end, and the N-cadherin-p120 catenin complex excludes integrin alpha5 at the junction
129 uctural studies have shown that the cadherin-catenin complex exists as an ensemble of flexible confor
130 n deacetylation, thereby enhancing LEF1-beta-catenin complex formation and long-range chromatin loopi
131 AB11A and Merlin, we observed enhanced YAP-B-catenin complex formation and nuclear translocation.
133 d with increased cytoplasmic N-cadherin-beta-catenin complex formation as well as enhanced beta-caten
134 on of beta-catenin or inhibition of Tcf/beta-catenin complex formation reduced EpCAM gene expression
135 al cell polarity and affects E-cadherin/beta-catenin complex formation through the control of Wnt5a e
136 n of monomeric catenins and stabilization of catenin complex formation with both APC and cadherins.
137 argely constitutive and integral to cadherin-catenin complex formation, surface stability, and functi
139 d assay, we showed that the minimal cadherin-catenin complex formed stable bonds with an actin filame
140 romote the transition of ABD in the cadherin-catenin complex from an ensemble of diverse conformation
141 nd beta-catenin, probably as intact cadherin-catenin complexes from the basolateral membrane of tubul
142 tion of the ZA proteins as intact E-cadherin-catenin complexes from the plasma membrane facilitates t
144 We also demonstrate that the E-cadherin/catenin complex functions as an upstream regulator of th
145 is unknown whether homologs of the cadherin.catenin complex have conserved structures and functions
147 data suggest that APC-catenin and E-cadherin-catenin complexes have opposing effects on intestinal ep
148 N-cadherin and the assembly of the cadherin-catenin complex in cells that express endogenous N-cadhe
149 expression of VE-cadherin/p120-catenin/beta-catenin complex in co-cultured H5V cells was also assess
150 suggest that perturbation of the N-cadherin/catenin complex in heart disease may be an underlying ca
153 n we observed between PTPmu and the cadherin-catenin complex in immunoprecipitates of the phosphatase
154 ial barrier by disrupting a VE-cadherin-beta-catenin complex in lung endothelium from wild-type, but
155 estoration of membrane-associated E-cadherin/catenin complex in TGF-beta1/Delta(beta)RII compound tum
158 osphatase PTPmu associates with the cadherin-catenin complex in various tissues and cells and, theref
160 portant binding partner of the Cadherin-11/B-Catenin complex in zipper-like cell-to-cell contacts.
161 a) caused the disruption of VE-cadherin/beta-catenin complexes in a Src-dependent manner, decreased b
162 s with the HepII domain caused cadherin/beta-catenin complexes in adherens junctions and actin filame
165 ene is activated by T cell factor (TCF)-beta-catenin complexes in transient transfection assays, sugg
166 ociated PSD-95 and N-cadherin from the delta-catenin complex, increased the association of delta-cate
167 ly, a cross-linking analysis of the cadherin-catenin complex indicated that a large loop located in t
168 high affinity unlike the beta-catenin.alphaE-catenin complex, indicating that alphaT-catenin can dire
169 easurements to examine how multiple cadherin-catenin complexes interact with F-actin under load, and
170 cate that localized clustering of E-cadherin/catenin complexes into puncta and their association with
171 that the intracellular level of the cadherin/catenin complex is a limiting factor during critical sta
173 e transactivating function of the LEF-1/beta-catenin complex is critical for tumorigenesis and that t
174 ation of the cytoskeleton with the cadherin--catenin complex is essential for strong cell-cell adhesi
176 n is initiated, suggests that the N-cadherin/catenin complex is involved in boundary formation and in
177 lly assembled APC-Axin-GSK3beta-phospho-beta-catenin complex is necessary for the K63-polyubiquitylat
178 ner, and their association with the cadherin-catenin complex is reduced in cells treated with NGF.
180 strates that the disruption of cadherin-beta-catenin complexes is an important molecular event throug
184 That PS1 is a constituent of the cadherin/catenin complex makes that complex a potential target fo
186 The classical cadherin.beta-catenin.alpha-catenin complex mediates homophilic cell-cell adhesion a
187 tumor-suppressor genes that encode cadherin/catenin complex members E-cadherin and alpha-catenin, re
188 ta-catenin and other members of the cadherin/catenin complex, namely N-cadherin and alphaN-catenin, e
189 aE9 increased neither the levels of cadherin/catenin complexes nor cell aggregation, suggesting that
190 hypertrophic chondrocytes, TCF x LEF x beta-catenin complexes occupy the consensus TCF x LEF x Sox9
191 dings suggest that targeting the YAP/TEAD4/B-catenin complex offers a potential therapeutic strategy
192 ly, upon inactivation of the entire cadherin-catenin complex, only adhesive strengthening between fil
195 migration, whereas augmentation of APC-beta-catenin complexes produces a disordered, nonadhesive mig
196 dhesiveness; augmentation of E-cadherin-beta-catenin complexes produces a highly ordered, "adhesive"
197 that Pp1 promotes proper levels of cadherin-catenin complex proteins at cell-cell junctions within t
198 tenin (p120ctn), a component of the cadherin-catenin complex, recruits gamma-secretase to cadherins,
203 increasing the relative activity of cadherin-catenin complexes, resulting in enhanced adhesiveness an
204 ipulation of myosin-II activity and cadherin-catenin complexes revealed that this transmission is med
205 he 3.0 A structure of a beta-TrCP1-Skp1-beta-catenin complex reveals the basis of substrate recogniti
207 partners converge to stabilize the cadherin-catenin complex's inherently weak binding to actin filam
208 ions, ternary E-cadherin/beta-catenin/alphaE-catenin complexes sense and transmit mechanical load by
210 ormation of an entropic trap in the cadherin-catenin complex, serving as negative allosteric regulati
211 with actin filaments and the E-cadherin-beta-catenin complex simultaneously, even in the presence of
212 and cytoplasmic pools to regulate E-cadherin/catenin complex stability and cell migration, respective
213 ate steady-state catenin levels and cadherin-catenin complex stability are poorly understood, but act
215 known features of p120-catenin in a cadherin-catenin complex that are critical for our understanding
217 As c-jun is a direct target of the TCF4/beta-catenin complex, the control of tcf4 expression by JNK/c
220 role in the stabilization of the E-cadherin-catenin complex, thereby providing one possible explanat
221 recruits beta-2-spectrin to E-cadherin-beta-catenin complexes, thus providing a direct connection be
224 show that ZOO-1 cooperates with the cadherin-catenin complex to dynamically regulate strong junctiona
225 tein that can physically couple the cadherin.catenin complex to F-actin in the absence of tension.
226 t to the cooperative binding of the cadherin-catenin complex to F-actin, which regulate dynamic cytos
227 mechanisms by which it anchors the cadherin-catenin complex to the actin cytoskeleton at adherens ju
228 in the heart, directly couples the cadherin-catenin complex to the actin cytoskeleton at the interca
229 role in the direct anchorage of the cadherin-catenin complex to the actin cytoskeleton, has remained
236 n PIP5K1alpha is recruited by the E-cadherin-catenin complex to the plasma membrane where it provides
238 regulate chemotactic response and ZO-1/alpha-catenin complexes to regulate endothelial barrier integr
239 to which alpha-catenin bridges cadherin.beta-catenin complexes to the actin cytoskeleton has been cha
240 These results may explain how the cadherin-catenin complex transduces mechanical forces at cell-cel
241 junction in cell-cell adhesion, the cadherin-catenin complex transduces mechanical tension between ne
242 g actin filaments and immobilized N-cadherin/catenin complexes, translating into a local reduction of
244 cale protein domain dynamics of the cadherin-catenin complex using neutron spin echo spectroscopy (NS
245 of PI3K to the E-cadherin/beta-catenin/p120-catenin complex via beta-catenin at the plasma membrane
247 that this complex containing Smads/TCF4/beta-catenin complex was able to up-regulate transcription at
248 he polycystin-1/polycystin-2/E-cadherin/beta-catenin complex was disrupted and both polycystin-1 and
249 t the association of Erbin with the cadherin-catenin complex was mediated by the interaction of its P
252 While the protein levels of the cadherin/catenin complex were significantly induced during AF-236
254 might interact with the Axin.APC.GSK-3.beta-catenin complex, where it could modulate the effect of G
255 n depend specifically on the N-cadherin-p120 catenin complex, whereas myosin II light chain and actin
256 translocation in hepatocytes is the Met-beta-catenin complex, which appears to be independent of the
257 ng cell-cell adhesion through the E-cadherin-catenin complex, which controls formation and maintenanc
258 nduced the formation of a B-arrestin 1/Src/B-catenin complex, which further triggered the nuclear tra
259 ed PGE(2) induces the formation of EGR1-beta-catenin complex, which interacts with T-cell factor 4/ly
261 120 is a key linker cementing the E-cadherin-catenin complex with the transmembrane protease gamma-se
262 lized and coprecipitated with ARVCF or delta-catenin complexed with beta-catenin and E/N-cadherin.
263 Coimmunoprecipitation confirmed that beta-catenin complexed with both p65 and p50 NF-kappaB protei
265 ngth of the association of multiple cadherin/catenin complexes with F-actin, conferring positive feed
266 atically increased interaction of E-cadherin-catenin complexes with vinculin and the actin cytoskelet
267 to the junction in parallel to the cadherin-catenin complex, zoo-1 loss of function reduces the dyna