ライフサイエンスコーパス: causal relationship

1 in HSCs within their native niche suggest a causal relationship.

2 n issued, and the authors make no claim of a causal relationship.

3 are investigated in an effort to evaluate a causal relationship.

4 here remains a lack of evidence to suggest a causal relationship.

5 d clinical trial is necessary to determine a causal relationship.

6 r FDG uptake, but there was no evidence of a causal relationship.

7 an randomization (MR) provided evidence of a causal relationship.

8 and Re-Os isotopes to further explore their causal relationship.

9 Further studies are needed to confirm a causal relationship.

10 reased impulsive action, thus establishing a causal relationship.

11 ecurrent stroke if further studies confirm a causal relationship.

12 tify pairs of traits that show evidence of a causal relationship.

13 ontal disease if further studies establish a causal relationship.

14 nal injury, would enhance plausibility for a causal relationship.

15 features in extant bilaterians, suggesting a causal relationship.

16 oral association and dose-response suggest a causal relationship.

17 ractive, some research does not support this causal relationship.

18 unclear whether these associations reflect a causal relationship.

19 were used to investigate genetic overlap and causal relationships.

20 lated, which makes it difficult to elucidate causal relationships.

21 hese approaches are incapable of identifying causal relationships.

22 iangulated to improve confidence in inferred causal relationships.

23 nd raise questions on their significance and causal relationships.

24 me for 55 pairs of traits that show putative causal relationships.

25 states that can hinder the identification of causal relationships.

26 inimizing biases in predicting or diagnosing causal relationships.

27 offer guidance to accurately discover known causal relationships.

28 ther work is necessary to identify potential causal relationships.

29 ial intelligence routines are augmented with causal relationships(17,18), allowing it to 'strategize'

30 Together, our data support a direct causal relationship among centrosome amplification, geno

31 These results suggest a causal relationship among epigenomic state, TXNIP expres

32 ged as a major tool for the investigation of causal relationship among traits, utilizing results from

33 ation, we learned models containing putative causal relationships among 12 proteins involved in T cel

34 The causal relationships among drug-induced alterations, coc

35 of the immune component of IBD that informs causal relationships among loci previously linked to IBD

36 functional measurements-to parameterize the causal relationships among regions of a distributed brai

37 Moreover, the causal relationship and functional consequences of LLPS

38 the gut microbiota and obesity in humans, a causal relationship and the underlying mechanism remain

39 endelian randomization analysis, we estimate causal relationships and provide evidence suggesting tha

40 To study how causal relationships are learned and effected, we devise

41 The inferred causal relationships are statistically robust and biolog

42 The model also infers causal relationships based on the most important transcr

43 Stimulation data indicated the causal relationship between (i) superior-temporal gyrus

44 randomisation(MR) approach, we examined the causal relationship between 25(OH)D and cognitive functi

45 approach has the potential to investigate a causal relationship between a risk factor and a disease,

46 Also, there is a causal relationship between activation of YY1 and ERBB2

47 ories engages reward-related circuits, but a causal relationship between activity in a reward circuit

48 This study investigates the causal relationship between adiponectin levels and metab

49 udies and experimental animal models shows a causal relationship between adverse pregnancy and increa

50 The causal relationship between amygdala serotonin levels an

51 in reuptake inhibitors (SSRIs) confirmed the causal relationship between amygdala serotonin transport

52 rg3.1 knock-out (KO) mice to investigate the causal relationship between Arc/Arg3.1 deletion and schi

53 , longitudinal experiment, demonstrating the causal relationship between authentic posting and positi

54 In addicted populations, however, the causal relationship between biobehavioral phenotypes of

55 Our data are consistent with a causal relationship between BMI and incident AF.

56 We aimed to investigate a possible causal relationship between body mass index (BMI) and ps

57 and it has been proposed that there exists a causal relationship between both processes.

58 mplements neural measurements by probing the causal relationship between brain and perception, cognit

59 However, the causal relationship between CE-induced brain changes and

60 A causal relationship between cell metabolism and the fate

61 Here, we identify a causal relationship between cerebellar output and mouse

62 Nevertheless, the causal relationship between changes in DNA methylation a

63 Our goal is now to provide a causal relationship between changes in prefrontal PV(+)

64 To determine the causal relationship between changes in pTau and PIP2/syn

65 used the instrumental variable to model the causal relationship between choice of NOAC and major ble

66 Optogenetic studies support a causal relationship between cholinergic transients and b

67 These results demonstrate a causal relationship between complement dysregulation and

68 ic memory retrieval, and (ii) understand the causal relationship between cortical network nodes and o

69 otor high beta bursts, suggesting a possible causal relationship between corticocortical synchrony an

70 in nature; thus, we are unable to conclude a causal relationship between covariates and AKI and do no

71 In this natural experiment, we confirmed the causal relationship between deteriorating socioeconomic

72 However, causal relationship between dysbiosis and constipation r

73 entromedial prefrontal cortex (vmPFC), but a causal relationship between dysregulation of these areas

74 c defects in Cnr mutant livers, suggesting a causal relationship between EC signaling, methionine def

75 cular alterations, arguing against a primary causal relationship between elevated ICP and spaceflight

76 ng scientific evidence was consistent with a causal relationship between exposure to fine particulate

77 glycolysis reduced inflammation suggesting a causal relationship between flow-induced metabolic chang

78 In this article, we uncover an unexpected causal relationship between Foxp3-transcriptional activa

79 This study aimed to assess a potential causal relationship between genetic variants associated

80 However, the causal relationship between GPe neuron classes and movem

81 These results provide support for a causal relationship between growth stunting and componen

82 ther investigated in the future to study the causal relationship between gut microbial metabolites an

83 To test the causal relationship between H + T-induced RNA-chromatin

84 explore current perspectives on the possible causal relationship between hearing loss, neural reorgan

85 This study provides evidence of a causal relationship between higher alcohol consumption a

86 Our results support a potentially causal relationship between higher physical activity lev

87 onal activation domain of VP16, suggesting a causal relationship between HMR-mediated activation of P

88 highlight the importance of establishing the causal relationship between images and their annotations

89 more promising approaches for estimating the causal relationship between income and health.

90 Our data support a causal relationship between KCNE2 gene disruption and lu

91 The identified causal relationship between LDL and ALS is robust with r

92 ive reading intervention program to test the causal relationship between learning to read and motion

93 domization analyses performed to date on the causal relationship between lipids and ALS.

94 changes in body weight, lending support to a causal relationship between loss of CB1 in adipocytes an

95 However, a causal relationship between M1 activity during asymptote

96 Here, we investigate the causal relationship between macronutrient composition, i

97 ome editing and 3C assays, we demonstrated a causal relationship between methylation within the IRX2

98 To date, few studies have investigated the causal relationship between mortality and long-term expo

99 Yet, the causal relationship between motion sensitivity and readi

100 However, the causal relationship between MPO and the development and

101 Here, we directly explore the assumed causal relationship between multinucleation and establis

102 Their findings reveal what could be the causal relationship between multiple pathogenic pathways

103 ows high-throughput, label-free study of the causal relationship between nanoscale organization and m

104 studies are required to fully elucidate the causal relationship between needle size and post-procedu

105 al to trial, offering a means of testing the causal relationship between network activity and human t

106 the cerebral cortex; however, evidence of a causal relationship between network interactions and cor

107 injured Ia afferents, suggesting a possible causal relationship between neuroinflammation and Ia axo

108 etic learning, in which we could control the causal relationship between neurons and behavior, we fou

109 and experimental studies have demonstrated a causal relationship between neutrophils and metastasis(4

110 Our results demonstrate a direct causal relationship between newborn neuronal activity an

111 However, a causal relationship between NT-proBNP and clinical endpo

112 However, the causal relationship between obesity and diabetes, increa

113 Knowledge about the causal relationship between objects has been studied ext

114 nts further study to establish a potentially causal relationship between OR door openings and the occ

115 tory function in left auditory cortex, but a causal relationship between oscillatory function and pho

116 These data do not suggest a causal relationship between osimertinib and cardiac fail

117 In our opinion, the proposed causal relationship between OV infection and NS has yet

118 trol, it has been difficult to establish the causal relationship between pallidal activity and motor

119 Brain stimulation studies suggest a causal relationship between parietal alpha and suppressi

120 However, the causal relationship between Plk1 up-regulation and tumor

121 ation between 2012 and 2017, to estimate the causal relationship between pollution and inhaler use.

122 erdisciplinary evidence of the bidirectional causal relationship between poverty and common mental il

123 Mendelian randomization analysis suggests a causal relationship between pro-ENK level and deteriorat

124 Recent reviews have proposed a causal relationship between prolonged breastfeeding and

125 As a causal relationship between protein aggregation and neur

126 Mendelian randomization identified a causal relationship between psoriasis and T2D (P = 1.6 x

127 this longitudinal study, we investigated the causal relationship between pubertal maturation and asth

128 The causal relationship between RA and AD was assessed using

129 ility in several RGS isoforms and supports a causal relationship between RGS flexibility and the pote

130 This strongly suggests a causal relationship between RGS protein flexibility and

131 There is strong evidence for a causal relationship between salt intake and blood pressu

132 emerging body of evidence supports a direct causal relationship between serum urate levels and the d

133 rm Mendelian randomisation and demonstrate a causal relationship between short stature and higher ris

134 hatic system degrades with age, suggesting a causal relationship between sleep disturbance and sympto

135 to investigate associations in support of a causal relationship between smoking and alcohol consumpt

136 Our study thus provides evidence for a causal relationship between smoking and ALS.

137 s no strong evidence for a causal or reverse causal relationship between smoking and ALS.

138 idence is still lacking for the hypothesized causal relationship between social mobility and social s

139 ross-correlation analysis to investigate the causal relationship between solar activity, volcanic for

140 h using an unobtrusive method to establish a causal relationship between strategy and choice, randoml

141 se model of mammographic density supported a causal relationship between stromal stiffness, reduced m

142 xual arousal (3,723 adults) did not show any causal relationship between structural features and func

143 The causal relationship between systolic blood pressure (SBP

144 This confounds the determination of a causal relationship between the activation of specific m

145 Here, we show a clear causal relationship between the freeze-concentration eve

146 We aimed to investigate whether there is a causal relationship between the length of interpregnancy

147 To evaluate the causal relationship between the obesity-related traits a

148 y because of incomplete entries or because a causal relationship between the radiopharmaceutical and

149 on phase of three substorms, which implies a causal relationship between the substorms and the format

150 Furthermore, we establish a direct, causal relationship between the three-dimensional genome

151 ss of epithelial extrusion by establishing a causal relationship between the triggering events of apo

152 and mass extinctions has led many to pose a causal relationship between the two.

153 role models for healthy behaviours assumes a causal relationship between their health behaviours and

154 cally decoupled in time, refuting any direct causal relationship between them.

155 However, it is not known whether there is a causal relationship between these phenomena.

156 with an increased risk of obesity, however a causal relationship between these two conditions remains

157 Under the assumption of a causal relationship between timing of ANS and mortality,

158 detectable mammary tumors, thus suggesting a causal relationship between TMPRSS13 expression and the

159 types and Mendelian randomization, we find a causal relationship between trabecular morphology and ri

160 on remains a critical tool to understand the causal relationship between treatments and outcomes.

161 Structure-function analysis reveals a causal relationship between tubulin structure and MT sta

162 ings confirm that there is no precise linear causal relationship between tumor genotype and phenotype

163 WHERE NEXT?: Epidemiological evidence for a causal relationship between use of beta2-adrenoceptor an

164 This is evidence of a causal relationship between vitamin D-VDR signaling and

165 Although a causal relationship between Zika virus (ZIKV) and microc

166 n manner to explore genetic correlations and causal relationships between >700 phenotypic traits and

167 The purpose of this study was to infer causal relationships between 22 previously reported risk

168 iting in vivo to, for the first time, define causal relationships between a single chromatin modifica

169 The aim of this research was to ascertain causal relationships between a wide range of haematologi

170 Identifying causal relationships between acid mine drainage (AMD) an

171 l method that can be used to investigate the causal relationships between an exposure and outcome by

172 A full understanding of the causal relationships between behavioural and molecular c

173 interactions by representing them as binary, causal relationships between biological entities.

174 that stores signaling information as binary causal relationships between biological entities.

175 Genetic variation can be used to study causal relationships between biomarkers and diseases.

176 Together, this may help inform causal relationships between biomarkers and neurological

177 fore performed a systematic investigation of causal relationships between circulating lipids and card

178 nalysis, an econometric tool for quantifying causal relationships between complex time-series, was de

179 lian randomization, we were able to identify causal relationships between corneal biomechanics and in

180 Efforts to decipher the causal relationships between differences in gene regulat

181 n relevant functional pathways, we infer the causal relationships between disparate endothelial funct

182 Determining causal relationships between distinct chromatin features

183 del causal inference approach to investigate causal relationships between epidemiological, laboratory

184 e leverage these genetic maps to predict 213 causal relationships between expression and DNAme, appro

185 de association study (PTWAS), to investigate causal relationships between gene expressions and comple

186 molecular mechanisms of tumour progression, causal relationships between genes and the tumour suppre

187 randomization and colocalization to uncover causal relationships between genetic variants, BMI and d

188 allenge that limits the capacity to identify causal relationships between host-associated microorgani

189 zation was then used to validate potentially causal relationships between identified factors and depr

190 However, our understanding of the causal relationships between lung injury and kidney inju

191 Since the causal relationships between MD-PFC abnormalities and co

192 ome-wide association studies to evaluate the causal relationships between methylation levels and 14 c

193 omputational strategy to infer probabilistic causal relationships between network components based on

194 ting that network manipulation may establish causal relationships between network markers and clinica

195 However, identifying causal relationships between past climate change and bio

196 Evidence is inadequate to establish causal relationships between PPI therapy and many of the

197 No definitive causal relationships between pregnancy and OI could be e

198 examination of the genetic evidence for the causal relationships between previously reported risk fa

199 now stores almost 23 000 manually-annotated causal relationships between proteins and other biologic

200 ters the gut microbiota in aged animals, the causal relationships between rapamycin treatment, microb

201 causal inference algorithm (TCI) to identify causal relationships between SGAs and differentially exp

202 , which estimates causative SGAs by modeling causal relationships between SGAs and molecular phenotyp

203 Establishing causal relationships between specific features of sleep

204 ed-loop experiments are crucial to delineate causal relationships between the activity of genetically

205 chnical advance towards the establishment of causal relationships between the chemistry and microbial

206 itudinal studies are crucial for discovering causal relationships between the microbiome and human di

207 ranscripts has hampered efforts to elucidate causal relationships between the presence of a specific

208 However, the causal relationships between TRPV1 phosphorylation and p

209 rol); (2) drugs without prior evidence for a causal relationship, but potentially worth further explo

210 We also observe causal relationships (by Mendelian randomisation analysi

211 atheter ablation of PVCs demonstrates that a causal relationship can be present.

212 egulation and sleep disturbances, although a causal relationship cannot be established in this cross-

213 Based on the observational study design, a causal relationship cannot be proven, and respective lim

214 Although a causal relationship cannot be ruled out, the previously

215 Causal relationships cannot be established from this stu

216 Causal relationships cannot be inferred, and opioid pres

217 a general consensus about what constitutes a causal relationship: causes both precede and predict eff

218 tion-based computational methods to discover causal relationships, CSD methodologies are gaining popu

219 alaria influence each other in bidirectional causal relationships-deforestation increases malaria thr

220 included (1) drugs with prior evidence for a causal relationship (e.g., megestrol); (2) drugs without

221 Despite the causal relationship established between malignant mesoth

222 However, it remains unclear whether a causal relationship exists between lipids and BC.

223 We tested the hypothesis that a causal relationship exists between systolic BP (SBP) and

224 tabolically healthy phenotype, but whether a causal relationship exists is not clear.

225 Mendelian randomization (2SLS MR) to show a causal relationship for 21 of the CpGs.

226 Establishing a pathway of causal relationship for obesity and periodontitis could

227 iscovery (CSD) is the problem of identifying causal relationships from large quantities of data throu

228 upport the use of MR as a means to elucidate causal relationships from microbiome-wide association fi

229 ether (i) CSD methods can discover the known causal relationships from observational clinical data an

230 The ability to accurately predict the causal relationships from transcription factors to genes

231 Supportive of a causal relationship, genetically predicted BMI was posit

232 rgy (FA) is not fully understood, although a causal relationship has been suggested.

233 nd pharmacological disinhibition; however, a causal relationship has not been established at the cell

234 gly associated with exercise capacity, yet a causal relationship has not been established.

235 iated with gene activities, studies of their causal relationships have been difficult.

236 localization moves it closer to establishing causal relationships: if a GWAS trait and a gene's expre

237 epression but we did not find evidence for a causal relationship in our Mendelian randomization analy

238 urons selectively inhibited to determine the causal relationship in this circuit.

239 To elucidate causal relationships in CHANS, multiple approaches will

240 re powerful statistical models to understand causal relationships in real-world probabilistic problem

241 due to the lack of in-depth understanding of causal relationships, in particular between acute exposu

242 ciency and obesity and/or type 2 diabetes, a causal relationship is not established.

243 type II autoimmunity has level 2 causality (causal relationship likely).

244 Through detailed investigation of several causal relationships, many pleiotropic pathways are unco

245 Our results suggest that learning causal relationships may be feasible in complex settings

246 rrelational, and so whether and what kind of causal relationships might exist are unclear.

247 ings with computational modeling, we infer a causal relationship, namely that changes in white matter

248 ndelian randomization analysis to assess the causal relationship of birth weight (~140,000 individual

249 nce after correction for heterogeneity-for a causal relationship of elevated CRP levels with psoriati

250 mproved capability to resolve the timing and causal relationship of events in the geologic record.

251 trate a concordant, positive and potentially causal relationship of lymphocyte count with systolic BP

252 weighted approach, we identified a potential causal relationship of lymphocyte count with systolic BP

253 Mendelian randomization supports a stronger causal relationship of measured serum levels with SHR (f

254 As a result, the causal relationship of most of these genetic variants in

255 However, the causal relationship of such observation remains unclear.

256 However, the causal relationship of these events remains unclear.

257 o gain insights into the genetic overlap and causal relationship of these two traits.

258 We assessed a causal relationship of WMH to methylene tetrahydrofolate

259 al moves protocol can be used to investigate causal relationships of functional motions in biological

260 underlying pathophysiological processes and causal relationships of insomnia with disease are poorly

261 istent predictive utility of cVL arises from causal relationships or from statistical artifacts.

262 However, these studies do not test the causal relationship, or 'codependency', whereby the comp

263 highlighting the importance of using robust causal relationships over illusive correlations to detec

264 gene expression, but questions regarding the causal relationship remain.

265 However, the causal relationships remain largely unresolved.

266 A substantial and potentially causal relationship remained after accounting for a hist

267 oping Alzheimer's disease (AD), although the causal relationship remains poorly understood.

268 Whether these associations represent causal relationships remains uncertain.

269 Establishing such causal relationships requires precise manipulation of th

270 the path to accumulating an evidence base on causal relationships requires skills and knowledge from

271 in patients with CSU has level 3 causality (causal relationship suggested), and type II autoimmunity

272 Our findings revealed a more nuanced causal relationship than previously suggested, providing

273 ticles (UFP) remains insufficient to infer a causal relationship that is largely due to different siz

274 Learning the causal relationships that define a molecular system allo

275 ent GWAS studies, we find that CAUSE detects causal relationships that have strong literature support

276 isms of this plasticity and whether it has a causal relationship to allodynia remain unsolved.

277 ransmission in South America in 2015 and its causal relationship to devastating anomalies in newborn

278 gnaling axis, we validate whether there is a causal relationship to electrotaxis and these mechanisms

279 oimmunity in patients with CSU from level 1 (causal relationship) to level 5 (causality not likely).

280 To further probe causal relationships, two-sample Mendelian randomisation

281 nd that of atmospheric CO(2) could suggest a causal relationship, we here unambiguously demonstrate t

282 To delineate the causal relationship, we used various mouse models with v

283 To investigate causal relationships, we inhibited the RNA-binding prote

284 in these methods often do not model discrete causal relationships well.

285 06 [95% CI, 0.97-1.15]; P=0.2), likely has a causal relationship with AAA development.

286 an randomization (MR) was used to test for a causal relationship with BMI.

287 ers are needed to truly define if there is a causal relationship with increased toxicity when piperac

288 ers are needed to truly define if there is a causal relationship with increased toxicity when piperac

289 showed a significant potentially protective causal relationship with risk of schizophrenia.

290 However, because of its causal relationship with severe congenital malformations

291 eficial, when prolonged and repeated shows a causal relationship with skin cancer risk.

292 ce (CAMP) has long been proposed as having a causal relationship with the end-Triassic extinction eve

293 tested whether metabolic-related traits have causal relationships with ACR.

294 based study (42,112 patients) and tested for causal relationships with multivariable Mendelian random

295 We report how different taxa are involved in causal relationships with others, and show that strong i

296 Genetics has also successfully established causal relationships with risk factors and holds promise

297 ds were evaluated by comparing the resulting causal relationships with the "gold standard" graph that

298 ipulations of suspected stressors to examine causal relationships with traits of free-living urban an

299 stand the mechanism underlying this putative causal relationship, with the goal of developing potenti

300 causal and hypothesize about and investigate causal relationships without estimating causal effects.