ライフサイエンスコーパス: causality

1 eficits (reduced posterior-->frontal Granger causality).

2 down inhibition (reduced frontal-->posterior causality).

3 ctus, this study addresses a key question of causality.

4 rowth status and considers issues of reverse causality.

5 We find evidence of reciprocal causality.

6 ed trials should be considered as a proof of causality.

7 Additional research is required to determine causality.

8 studies included does not allow for proving causality.

9 nderstand the observed association and their causality.

10 when assessing the validity of estimates and causality.

11 cal formalisms without saying anything about causality.

12 ngs may be biased by confounding and reverse causality.

13 f histological disease, therefore suggesting causality.

14 This observational study could not establish causality.

15 that we are unable to definitively determine causality.

16 oss-regional infection flow based on Granger causality.

17 h prioritizes genes with strong evidence for causality.

18 ts for key confounders and potential reverse causality.

19 ovel ADOA-associated genes and explore their causality.

20 rstanding, whereas neural interventions test causality.

21 necessary to provide additional evidence of causality.

22 sus statements to update the WHO position on causality.

23 probably because of confounding and reverse causality.

24 possible to rule out some effect of reverse causality.

25 The statistical analysis cannot establish causality.

26 rted as pathogenic in CAKUT did not indicate causality.

27 ased study designs were used to further test causality.

28 tional, no conclusions can be made regarding causality.

29 dentified variants is crucial to demonstrate causality.

30 f an expert assessment of the evidence about causality.

31 sease markers without apriori assumptions of causality.

32 y in CSU with the help of Hill's criteria of causality.

33 an air pollution study provides evidence of causality.

34 ses in K cell spike rates by 1-3 s, implying causality.

35 iagnosis of dementia and to minimize reverse causality.

36 R), we sought to strengthen the evidence for causality.

37 tive data to provide confident assignment of causality.

38 nalyses were bidirectional to assess reverse causality.

39 lian randomisation (MR) analyses to test for causality.

40 to the understanding of objects, space, and causality.

41 ter-relationship with possible bidirectional causality.

42 lication in observational studies evaluating causality.

43 dysregulation, but it is difficult to assess causality.

44 egative relationship between correlation and causality.

45 anulysin and interferon-gamma to confirm the causalities.

46 delian randomization (MR) analyses to assess causality(3), we found that the host-genetic-driven incr

47 nificantly correlated with DG -> CA1 Granger causality, a well-established analytical measure of dire

48 ve generally used correlation as a proxy for causality although there is a general consensus about wh

49 ment focuses on difficulties in establishing causality among various phenomena present in early moder

50 posure is unlikely to be affected by reverse causality (an important source of bias in this context)

51 ted causality approaches and for the role of causality analyses in neuroscience as a whole.

52 derived for wavelet transform coherence and causality analyses of the cardio-postural control and us

53 th many cardiometabolic traits, with genetic causality analyses supporting a substantial role for ple

54 performed source-level power, coherence, and causality analyses to characterize the underlying interr

55 Granger-causality analysis also supports the latter finding.

56 Spectral Granger-causality analysis revealed that the change in symmetric

57 xpression and methylation, while statistical causality analysis reveals multiple instances where meth

58 d and in reverse across regions, and Granger causality analysis suggests bidirectional information fl

59 Here, we conducted the first Granger causality analysis to identify the "causes" of groundwat

60 Granger causality analysis was consistent with the OB as the sou

61 Using Granger causality analysis, we identified inferior frontal corte

62 Although the causality and direction of these associations remain unk

63 To examine causality and elucidate how localized Plexin-B1 stimulat

64 Further studies are required to define causality and establish a role for systemic immune syste

65 Studies to confirm causality and investigate mechanisms may contribute to u

66 Further studies to confirm causality and investigate mechanisms will contribute to

67 th biological features of the brain, such as causality and locality.

68 mized, placebo-controlled trials, where both causality and magnitude of risk can be inferred.

69 , including ulcerative colitis (UC), but the causality and mechanisms remain unknown.

70 e in 80,003 participants and investigate the causality and potential mechanisms of the association be

71 number of studies and concern about reverse causality and recall bias prevent stronger conclusions.

72 tions about ecological interactions, Granger causality and related techniques may be particularly hel

73 Concerns about reverse causality and selection bias complicate the interpretati

74 ate the importance of accounting for reverse causality and selective attrition in studies of older ad

75 To examine reverse causality and selective attrition, we compared rate rati

76 iment are more likely to provide evidence of causality and should be prioritized among the body of ev

77 To confirm disease causality and translate such a genetic vulnerability int

78 which probes beneath the surface of abstract causality and unveils the nature of causal interactions.

79 dence with potential for issues with reverse causality and wide variation in design, type/age of outc

80 t apes in tasks of physical (quantities, and causality) and social cognition (social learning, commun

81 r range of CFBs, considers issues of reverse causality, and adjusts for potential confounders to addr

82 Cohort studies cannot determine causality, and current disease severity criteria were no

83 ing these factors, as well as the magnitude, causality, and directionality of relationships across sp

84 Our observational study does not suggest causality, and does not encourage more extended lymphade

85 ovascular diseases, preclinical evidence for causality, and implications for risk prediction and miti

86 However, correlation is not causality, and synchronization may be a byproduct of att

87 Here we use the Wiener-Granger causality approach along with well-established cross-cor

88 usality, with implications for other related causality approaches and for the role of causality analy

89 support perceptual learning, formal tests of causality are lacking.

90 globally but empirical studies demonstrating causality are rare.

91 re unable to prove biologic plausibility and causality as randomized controlled trials have not been

92 the framework provided by classical work on causality as well as contemporary approaches to predicti

93 After likelihood of causality assessment by established guidelines, six vari

94 Roussel-Uclaf Causality Assessment Methods identified one "possible" c

95 Granger causality-based effective (directed) connectivity was us

96 ion of this study is the inability to assess causality because of its observational nature.

97 dies, but it has been difficult to establish causality because of the possibility of residual confoun

98 the patterns detected here, and to establish causality between BCG vaccination and protection from se

99 oth directions to establish the direction of causality between BMI and AD.

100 randomization (MR) to infer the direction of causality between BMI and disordered eating in childhood

101 We showed no evidence of causality between BMI and EDs in adulthood in either dir

102 ng with EDU/SES also revealed unidirectional causality between brain morphology, psychopathology and

103 g earlier in development in ASD will tap the causality between changes in perceptual and symptomatolo

104 elusive, our results imply a high degree of causality between clock gene expression and one of the p

105 These simulations thus establish causality between currently unexplained, long timescale

106 rt that is required to decipher the circular causality between floods and rivers.

107 To determine causality between genetics and disease, accurate models

108 inverse-variance weighted method to test for causality between later life cognitive ability, educatio

109 ed on target validation methods to study the causality between modulating the RNA motif in vitro and

110 lity and aid in determining the direction of causality between PTSD and inflammation.

111 an intrinsic consequence of LV dysfunction, causality between SMR and mortality should not be implie

112 Supplementation experiments established causality between specific RCS and browning and allowed

113 Establishing causality between the clinical severity and outcomes for

114 The data presented here show that causality between the Karoo LIP and the late Pliensbachi

115 egulated LMO2 expression, establishing clear causality between the mutation and oncogene dysregulatio

116 ive model that dispenses with assumptions of causality between the two phenomena and explains mood re

117 y was estimated using non-parametric Granger causality between visual areas V1 and V4.

118 ed associations may be influenced by reverse causality bias cannot be excluded.

119 al biomarker results may suffer from reverse causality bias, whereby obesity status influenced the bi

120 nt LDIR exposures, likely reflecting reverse causality bias.

121 s of cancer, raising concerns about reversal causality bias.

122 undamental properties of Granger-Geweke (GG) causality, both computational and conceptual.

123 Case reports cannot establish causality, but they can reveal patterns in the timing of

124 th red and processed meat and cheese reflect causality, but they were consistent with the association

125 We attempted to infer causality by comparing the effects of maternal versus pa

126 policies to address treatment disparities if causality can be identified.

127 e observational nature of the present study, causality cannot be confirmed.

128 y is observational and conclusions regarding causality cannot be inferred.

129 Although reverse causality cannot totally be ruled out, cheese diversity

130 ested), and type II autoimmunity has level 2 causality (causal relationship likely).

131 utoimmunity in patients with CSU has level 3 causality (causal relationship suggested), and type II a

132 nly did suppressed alpha power and bottom-up causality correlate with heightened frontal gamma power,

133 due to natural disease progression although causality could not be ruled out).

134 Lumping all questions about causality creates ambiguity about the utility of differe

135 Causality detection likely misidentifies indirect causat

136 a non-empirical nature about topics such as causality, determinism and reductionism when conducting

137 ge of sensitivity analyses exploring reverse causality, differential non-response and stability of te

138 at directly addressed either outcome and any causality dimension, used methods to expedite study sele

139 haly, we included 72 items; for eight of ten causality dimensions (all except dose-response relations

140 Our findings suggest that dark causality dominates the sovereign CDS network, indicatin

141 unction using both systems biology tools and causality-driven laboratory experimentation will be esse

142 tudy limitations were the inability to infer causality due to the cross-sectional nature of the surve

143 esults; (ii) even if estimated correctly, GG causality estimates alone are not interpretable without

144 Specifically, we show that (i) GG causality estimates can be either severely biased or of

145 , naris blockade, current source density and causality estimates.

146 be explained in terms of symptom-to-symptom causality, explanation requires a network of biological

147 Philosophers have explored the concept of causality for centuries.

148 rium in African populations to infer genetic causality for circulating resistin levels by performing

149 dels of reduced IgCAM expression, to suggest causality for cortical wiring defects.

150 An inducible catalase system, to test causality for the role of hydrogen peroxide, reversed th

151 mouse models will be necessary to establish causality for these genes.

152 mentia, there is limited evidence to support causality for this relationship.

153 rate," or "high" and then assigned levels of causality for type I and II autoimmunity in patients wit

154 effect-size distribution and probability of causality for variants with different annotations and jo

155 When inferring causality, four nonexclusive theoretical models can acco

156 First, in February 2016, we developed a causality framework that defined questions about the rel

157 To assess causality from drug exposure, true predrug baseline imag

158 ight that we are unable to reliably separate causality from horizontal pleiotropy.

159 Distinguishing causality from mere association typically requires rando

160 Inferring causality from observational studies, however, is subjec

161 Here we argue that ideas about causality from philosophy can help scientists to better

162 LFPs also revealed a higher Granger causality from the direction of entopallium to NCL and f

163 cal modelling of twin data suggesting direct causality from the former to the latter.

164 timulus feedback connectivity (i.e., Granger causality) from FFA to V1 predicted not only the categor

165 Granger causality (GC) analysis, an econometric tool for quantif

166 s long been an area of interest, but proving causality has been elusive.

167 eye rubbing are also implicated, but direct causality has not been proven.

168 number of ICU admissions at the end of life, causality has not been well established.

169 ry role through complex interactions, though causality has not yet been fully demonstrated.

170 puted(9-13,19-24), and attempts to establish causality have been hampered by limitations in the avail

171 mortality with increased IL-6 doesn't imply causality however lack of improvement by tocilizumab req

172 indings provide evidence against the reverse causality hypothesis and strengthen evidence for persona

173 behaviors of the system model; and (iii) GG causality ignores critical components of a system's dyna

174 Among medically evacuated US military combat causalities in Afghanistan, blood product transfusion pr

175 tion to these difficulties, by investigating causality in a low-risk and low-cost way.

176 Considering the importance of causality in anatomo-clinical approach and stressing the

177 use of classical considerations for judging causality in human studies, as well as triangulation and

178 nd to have strong or definitive evidence for causality in LQTS with atypical features, including neon

179 s.(1-5) Based on analytical methods to infer causality in neural activation patterns, it was conclude

180 pervasive problem of confounding and reverse causality in observational studies limits inference abou

181 value," which is related to the evidence for causality in observational studies that are potentially

182 ghlighted based on evidence supporting their causality in organ failure.

183 sensory-driven causal connectivity (Granger causality in the alpha band) during a resting state (eye

184 To examine causality in the reverse direction, MR analyses were use

185 urther studies to help assess directions and causality in these associations.

186 research have made it difficult to establish causality in this complex relationship.

187 tment-emergent adverse events, regardless of causality, in either treatment group (any grade) were fa

188 gets to identifying disease-related genes to causality inference.

189 s on circulating PUFA levels and the lack of causality inherent in observational studies.

190 The hidden nature of causality is a puzzling, yet critical notion for effecti

191 Instead, the causality is bidirectional because plasticity itself can

192 and policy-makers to argue that evidence of causality is necessary before implementing more stringen

193 Although the direction of causality is not clear, this association strengthens the

194 nce the activity of Clinton supporters, this causality is reversed for the fake news: the activity of

195 l disease is associated with seropositivity, causality is unproven.

196 They are afflicted by notorious causality issues (e.g. grandfather's paradox).

197 lts provide interesting insights into subtle causality issues underlying the simultaneous excitation

198 The causality link could be addressed in an interventional t

199 Limitations: Reverse causality may have biased the findings; however, results

200 Causality means that symbols must be transmitted with pr

201 bus passes and addressed bias due to reverse causality, measurement error, and time-invariant confoun

202 What do frequency-domain causality measures tell us about the functional properti

203 Frequency-domain causality measures, such as those of Geweke, as well as

204 re slightly higher than those of the Granger causality method and approximately the same as those of

205 cerns regarding the applicability of Granger causality methods in neuroscience.

206 Granger causality methods were developed to analyze the flow of

207 t of it, which indicates that thequestion of causality must urgently be answered.

208 of longitudinal studies (necessary to assess causality), non-random sampling of participants by many

209 tudies were primarily observational; neither causality nor directionality could be determined.

210 pproach to psychopathology hinges neither on causality nor on rationality.

211 om level 1 (causal relationship) to level 5 (causality not likely).

212 Achieving confidence in the causality of a disease locus is a complex task that ofte

213 setting, will allow for the investigation of causality of abnormal blood flow in CVD.

214 hich mixtures of air pollutants operate, the causality of air pollution-associated shifts in birthwei

215 Causality of alpha activity dynamics was implied by its

216 ide understanding of the natural history and causality of diseases since early in life.

217 bust human data corroborating the extent and causality of EndMT in adult CVDs.

218 Finally, we demonstrate the causality of FOXM1 in driving WEE1i sensitivity.

219 The causality of hepatitis C with respect to the pathogenesi

220 the clinical data implicating the potential causality of Lp(a)/oxidized phospholipids, describe emer

221 We thus addressed potential causality of NTD-associated Vangl1/2 mutations, from eit

222 tional, self-reported data, possible reverse causality of overweight and obesity on wealth, and the l

223 mine if viral load could provide evidence of causality of pneumonia, we compared viral load in the UR

224 Causality of the muscle-pump baroreflex was reduced on R

225 genic factor in sepsis and ICU mortality but causality of these associations has not been demonstrate

226 We aimed to examine the potential causality of these associations using Mendelian randomis

227 intervention studies are needed to determine causality of these biological and behavioral relations.

228 as may be limited but supports the potential causality of these consistent, early microbial changes i

229 clinical significance, reproducibility, and causality of these findings are disputed.

230 nature of this study does not allow to imply causality of these findings.

231 lenging to demonstrate experimental proof of causality of these risk alleles for renal disease.

232 The causality of this correlation was verified in mice with

233 Studies in mice support the causality of this relationship.

234 Then, we study the causality of those changes using Transfer Entropy to cap

235 ng the genetic architecture of RBM20 disease causality on a population level.

236 n euchromatin and heterochromatin and a dual causality on gene expression.

237 rant proposals, and ( 2) assess evidence for causality on the basis of different causal inference con

238 Inability to establish causality or incidence, variable quality of reports, pos

239 ough further research is needed to determine causality, our study suggests that targeting neuroinflam

240 a positive correlation was found between the causality pairing index and presence of stable RDs (P=0.

241 Global VF organization quantified by causality pairing index showed a negative correlation at

242 In organized VF with high causality pairing index values, GC vector mapping charac

243 s, (2) quantify global organization with the causality pairing index, a measure of neighboring causal

244 e were no significant differences in Granger-causality patterns in frontal-to-parietal or parietal-to

245 espan, studies tend to assume unidirectional causality: plasticity evolves under suitable rates of en

246 Assuming causality, population attributable risk fractions for ou

247 f celiac disease, but concerns about reverse causality precluded a conclusion about the relationship

248 n flow architecture through a Granger-Geweke causality prism.

249 on this analysis, we find that the notion of causality quantified is incompatible with the objectives

250 d risk of PD is likely the result of reverse causality rather than a biological effect of these drugs

251 in cancer, yet the underlying mechanisms and causality remain poorly understood(1-3).

252 Decisions about causality require systematic assessment to guide public

253 th influencing DNA methylation (i.e. reverse causality) requires further research.

254 We argue that evidence of causality should be gauged by a critical evaluation of d

255 has been no formal demonstration of disease causality since their discovery.

256 e measure satisfies three desired properties-causality, specificity, intrinsicality-and is shown to b

257 ound in the corresponding results of Granger causality test and LASSO method.

258 ance of DBN by comparing it with the Granger causality test and the least absolute shrinkage and sele

259 averagely 46% less than those of the Granger causality test, and 22% less than those of the LASSO met

260 climatic variability and changes in DO, and causality testing indicated that these relationships wer

261 pecies to Plasmodium abundance using Granger causality tests for time-series data collected over two

262 After outlining six characteristics of causality that are relevant to cancer, we emphasize the

263 nal studies intended to produce evidence for causality, the E-value be reported or some other sensiti

264 were to update and reassess the evidence for causality through a rapid and systematic review about li

265 lines to demonstrate how our system confirms causality through mutant phenotype reversion.

266 (CCM) is a non-linear approach to establish causality, thus, expected to decipher nonlinear causal c

267 We used Granger causality to analyze predictive relationships among the

268 We also used Granger causality to assess whether omitted variable confounding

269 ough the current study design does not allow causality to be inferred, it does support the theory tha

270 the favoured approach; however, attributing causality to educational intervention proves difficult i

271 However, assigning causality to genetic variants associated with a transcri

272 individuals using global reasoning on the RN causality to identify key-nodes.

273 ions, there is an urgent need for studies on causality, underlying mechanisms, and effective interven

274 We addressed this fundamental question of causality using longitudinal anatomical magnetic resonan

275 sk of coronary artery disease, and to assess causality using Mendelian randomization (MR).

276 mization (MR), a statistical method to infer causality using observational data.Methods: We measured

277 used and developed in part deal with Granger causality, Vector Autoregression, Estimation Stability w

278 Genetic co-heritability and causality via MR was assessed using data from the Intern

279 gnificant (p = 0.002) decline in EMG --> SBP causality was observed in the elderly group, compared to

280 Their causality was then demonstrated by a functional test.

281 for both the exposure and mediator to infer causality-was performed to examine the causal associatio

282 Assuming causality, we calculated the population attributable fra

283 c evidence, satisfying rigorous criteria for causality, we conclude strongly that lowering intake of

284 ling and do not provide an absolute proof of causality, we find that cognition pathways mediate a sig

285 omization approach that provides evidence of causality, we found that genetically predicted lung canc

286 To test causality, we implemented an exercise intervention that

287 To assess causality, we investigated hemodynamic and histological

288 To assess causality, we perturbed the function of Tet2, the second

289 To show causality, we stimulated CL in anesthetized macaques and

290 Building on different assumptions of causality, we train three composite models to score func

291 To address causality, we used chemogenetics in transgenic mice to s

292 l as a hybrid form that we refer to as "dark causality." We propose an algorithm which is validated b

293 The criteria for causality were met and potential sources of controversie

294 ommon grade >=3 adverse events regardless of causality were neutropenia (46%), thrombocytopenia (38%)

295 on grade 3-4 adverse events (irrespective of causality) were haematological abnormalities-namely, ana

296 nter-areal interactions, measured as Granger causality, were also dominant between these cortical lay

297 for genome engineering studies to establish causality will continue to be frustrated by an inability

298 ss extinctions has been proposed to indicate causality, with eruptive volatile release driving enviro

299 ide important conceptual clarification of GG causality, with implications for other related causality

300 becoming infected, which led to over 12,000 causalities worldwide.