ライフサイエンスコーパス: cell activity

1 -expressing tSCs directly dampen cytotoxic T cell activity.

2 IFNgamma and was associated with enhanced T-cell activity.

3 uce saccadic suppression of retinal ganglion cell activity.

4 We now show that Itch directly limits B cell activity.

5 re significantly impacted by CD4(+) T helper cell activity.

6 umor microenvironment and boost anti-tumor T cell activity.

7 al another dimension to the modulation of NK cell activity.

8 hat described above, which may reflect CD4 T cell activity.

9 population and an increase in in vitro stem cell activity.

10 , multiantigen targeting, and controllable T-cell activity.

11 n supply, an environmental regulator of stem cell activity.

12 OA-NO2 is capable of enhancing regulatory T-cell activity.

13 an important role in the regulation of stem cell activity.

14 Ptpn11 signaling a key function in satellite cell activity.

15 hat are not essential for the differentiated cell activity.

16 boost induced strong virus-specific CD4(+) T-cell activity.

17 vity in delta-cells but suppression of alpha-cell activity.

18 diposity, energy expenditure, and pancreatic cell activity.

19 ic and postsynaptic sides to maintain target cell activity.

20 gulation by T-helper 1 cell and regulatory T cell activity.

21 hibiting CD8 T cells, enhancing regulatory T cell activity.

22 lk and the resulting tumor-associated immune cell activity.

23 k of CRC compared with subjects with high NK cell activity.

24 ng an anti-fibrotic rational by enhancing NK cell activity.

25 ecute homeostatic and injury-responsive stem cell activity.

26 e processes ranging from bone growth to stem cell activity.

27 synaptic weights to produce predictive place cell activity.

28 ERD were observed for AC cells and vitreous cell activity.

29 n, while 3 sero (-) patients showed no CMV-T cell activity.

30 lity loci for CD and how these affect Paneth cell activity.

31 L-18 production, an important cytokine in NK cell activity.

32 -L1, which can lead to enhanced anticancer T-cell activity.

33 tinemia, hemophagocytosis, and diminished NK cell activity.

34 between IL-32 and IL-15 and their role in NK cell activity.

35 for diseases characterized by dysregulated B cell activity.

36 leotide exchange factors known to regulate T cell activity.

37 s that were associated with increased immune cell activity.

38 LA-4 immune checkpoints inhibit antitumour T-cell activity.

39 ynamic responses, neuroinflammation and stem cell activity.

40 for Nedd4-2 and Ndfip1 in IgE-dependent mast cell activity.

41 ation, and the age-dependent decline in stem cell activity.

42 with inactive Wnt signaling and robust stem cell activity.

43 high-throughput screening and understanding cell activity.

44 stasis in vivo, and this was intrinsic to NK cell activity.

45 ndocrine lineages, while retaining some stem cell activity.

46 ral positioning of individual and group-wise cell activity.

47 ify the MR as a direct regulator of CD8(+) T-cell activity.

48 in turn results from the dysregulation of B cell activity.

49 or-specific antigens and poor control over T cell activity.

50 ht the need for mechanisms to modulate CAR T-cell activity.

51 ension, an indicator of elevated, systemic T-cell activity.

52 gate tumor antigen to facilitate assays of T cell activity.

53 , whereas promoting APC activation rescued T cell activity.

54 5 expression grant the endodermal cells stem cell activity.

55 s synergistically with Tyr-73 to control NKT cell activity.

56 xplain multiple fundamental features of grid cell activity.

57 ty were identified in tumors with elevated B cell activity.

58 dulation, which is putatively linked to grid cell activity.

59 putational framework for understanding place cell activity.

60 vision pathway, independent from OFF bipolar cell activity.

61 locomotion nor consistently coupled to place-cell activity.

62 ing to identify additional features of place cell activity.

63 meostasis by dynamic control of somatic stem cell activity.

64 ibitory checkpoint signaling that controls T cell activities.

65 lar battery" conserving bioenergy to power T cell activities.

66 mall changes in the impedance resulting from cell activities.

67 cell cycle but not genes that regulate stem cell activities.

68 functions as a matrikine regulating multiple cell activities.

69 NK cells and T cells and downmodulated Treg cell activities.

70 MIF- but not CXCL12-elicited CXCR4 vascular cell activities.

71 ion and IL10 production and diminished CD8 T-cell activities.

72 miRNAs enriched in VSMCs and modulating the cells' activity.

73 ed a functional impact of HLA class II on NK cell activity(2,3), the NK cell receptors that specifica

74 urons mediate distinct features of pyramidal cell activity(4-6), the SCG2-dependent reorganization of

75 disease progression is driven by aberrant B cell activity accompanied by ER stress and metabolic dys

76 ity within the grid cell network drives grid cell activity across behavioral states.

77 he balance of principal tufted versus mitral cell activity across large expanses of the MOB in respon

78 Bidirectional manipulation of PV(+) cell activity affected neuronal spectral and sound inten

79 es pDC-induced MM-specific CD8(+) CTL and NK cell activity against autologous tumor cells.

80 cin (TLM) analogues that show improved whole cell activity against bacterial strains including methic

81 lockade and adoptive T-cell therapy, boost T-cell activity against the tumor, but these strategies ar

82 N) riboswitch, from a compound lacking whole-cell activity against wild-type GN pathogens into a comp

83 The variance of grid cell activity along saccade trajectories exhibits 6-fold

84 hree spatially-clustered regions of Purkinje cell activity along the rostrocaudal axis.

85 he forefront of pathogen-specific effector T cell activities and establish novel practical and concep

86 AK-null CAFs contribute to the reduced tumor cell activities and metastasis.

87 ociated secretory phenotype and reinforce NK cell activities and surveillance functions, which result

88 LAG-3 has shown promise for augmenting CD8 T cell activity and boosting pathogen-specific immunity.

89 might be enhanced by modulation of dendritic cell activity and by a decrease in T-cell activation, ef

90 ure the dynamic signature of invasive cancer cell activity and cell-migration-induced ECM and collage

91 intercellular communication, induces leader cell activity and collective migration through the engag

92 sought to verify the spatial nature of place cell activity and determine its sensory origin.

93 is pathway is important for regulating alpha-cell activity and glucagon secretion in human islets, we

94 y was associated with 1) higher levels of NK cell activity and IFN-gamma-induced protein 10 (IP-10) o

95 activate microglia, reduce neural precursor cell activity and impair cognition in mice.

96 reg cells in check, A20 thus integrates Treg cell activity and increased effector T cell survival int

97 of therapeutics is dependent on cytotoxic T-cell activity and is associated with a reduction in immu

98 is provides for efficient regulation of beta cell activity and is modulated by endogenous IGF-1/VEGF-

99 expression of HCN2 channels in ChIs enhances cell activity and is sufficient to rescue depressive phe

100 critically important in the control of stem cell activity and maintenance of the identity of differe

101 ntiation 40 (CD40), could also enhance CAR T cell activity and mediate increased antitumor activity o

102 refore, we explored the role of CCL7 in mast cell activity and motility in vitro and investigated the

103 fibrogenic cells, which influence satellite cell activity and muscle repair during hypertrophy and a

104 he KW cocktail modulated natural killer (NK) cell activity and neutrophil and monocyte phagocytosis i

105 uring ultrasonic stimuli that drive ganglion cell activity and observed micron scale displacements, c

106 e surface as the bacteria still maintain the cell activity and overproduce EPS.

107 ormal antigen-presenting cell function and T cell activity and polarization, thereby implicating both

108 or understanding the regulation of satellite cell activity and regeneration after muscle injury.Satel

109 o-antigenic epitopes that elicit cytotoxic T-cell activity and subsequent pressure to select for gene

110 ute directly to LHb-induced inhibition of DA cell activity and support the widely held proposition th

111 n, yet how mitochondrial dysfunction affects cell activity and synaptic transmission in psychiatric i

112 tudies of AP propagation features reflecting cell activity and the influence of pharmacological subst

113 suggest that the relationship between place-cell activity and theta oscillations in primate hippocam

114 Long-term LRCs lost stem cell activity and were a homogenous population of termin

115 al memory in a similar manner to rodent grid-cell activity and, therefore, strengthen the putative li

116 ct on long-term lineage contribution or stem cell activity and, unlike G-CSF, did not impede recovery

117 or kappa-light-chain-enhancer of activated B cells activity and the production of pro-inflammatory cy

118 The relationship between cells' activity and task features was mostly stable on s

119 re evidenced by close regulation of in vitro cell activities, and enhanced cell infiltration and vasc

120 erocytosis, negative regulation of dendritic cell activity, and dysregulated production of chemokines

121 ls, including invasive behavior, cancer stem cell activity, and greater resistance to chemotherapy an

122 ess insulin resistance and compensatory beta-cell activity, and have fewer metabolic syndrome signs a

123 CMV-specific CD8+ (CMV-Tc), CD4+ (CMV-Th) T cell activity, and natural killer (NK) cell number were

124 oriented by a need to reduce aversive orexin cell activity, and suggest a hypothalamic circuit for fi

125 CMV-T cell activity, anti-CMV IgG, and NK cell-mediated antibo

126 bsets shows that GA-dependent increased Breg cell activities are specifically supported by the B cell

127 Among the most defining features of grid-cell activity are the 60 degrees rotational symmetry of

128 Using a genome-scale T cell activity array, we identified Siglec-15 as a critic

129 o promote spatial group selection of granule cell activity as a function of timing of mossy fiber inp

130 , vestibular-induced eye movements, and hair-cell activity as assessed with FM dye labeling and micro

131 eaning (post-natal day [P]21), offline place cell activity associated with sharp-wave ripples (SWRs)

132 Hippocampal place-cell activity associated with theta oscillations encodes

133 Hippocampal place-cell activity associated with theta oscillations underli

134 rt novel mechanisms by which TRMs regulate T cell activities at tissue sites.

135 se-response relationship, suppressing mitral cell activity at high and low, but not intermediate, NE

136 n-parametric Mann-Whitney test to compare NK cell activity between subjects with no evidence of CRC a

137 ective was to determine the difference in NK cell activity between subjects with vs without CRC.

138 We found a significant difference in NK cell activity between the 23 subjects with CRC (based on

139 t has been implemented to provide stronger T-cell activity but carries the risk of creating undesired

140 oduced powerful tools for optical control of cell activity, but current tools suffer from a variety o

141 t a feedback inhibition of IL-15-mediated NK cell activity by IL-32alpha.

142 opted a regenerative strategy to expand stem cell activity by incorporating a transit-amplifying popu

143 4 on HIV MDSC, and controlled CMV-specific T cell activity by limiting CMVpp65-IFNgamma production an

144 e can differentially influence PFC pyramidal cell activity by nAChR modulation of layer II/III hierar

145 target density on tumour cells and abating T cell activity by promoting fratricide T cell killing and

146 ggests that 1,5-(PP)(2)-InsP(4) impacts beta-cell activity by regulating granule localization and/or

147 hroughput and dynamic measurement for living cell activities can benefit biological research and drug

148 demonstrated that effective increase in stem cell activity can be achieved by using growth factors de

149 promote tumor progression and inhibit immune cell activity can enhance antitumor immunity by reshapin

150 suggest that increased coherence of Purkinje cell activity can facilitate mossy fibre-driven spiking

151 nvironments, the population vectors of place cell activity changed more abruptly with distance betwee

152 etabolism would provide a powerful look into cell activity changes as cells differentiate to all the

153 The material showing the highest cell activity compared to the reference cell culture pla

154 issues, we report that different directional cell activities cooperate synergetically to achieve elon

155 e first time that the local induction of B10 cell activity could inhibit periodontal inflammation and

156 Granule cell activity covaried trial by trial to form a redundan

157 ghlighting alterations to intrinsic Purkinje cell activity, dendritic architecture and glutamatergic

158 ve chemogenetic silencing of natural GAD65LH cell activity depresses voluntary locomotion, and that G

159 rewards elicited markedly different granule cell activity despite identical stimuli and licking resp

160 Rather than driving cell activity deterministically or spontaneously, chemog

161 tibody-dependent cellular cytotoxicity and T cell activity did not correlate with protection.

162 sent evidence that highly patterned Purkinje cell activity drives a powerful tremor in otherwise norm

163 opose that in those states, exacerbated beta-cell activity due to increased insulin demand and increa

164 ignaling that may be exploited to enhance NK cell activity during ageing.

165 However, tendon cell activity during growth and homeostatic maintenance

166 ignaling microenvironment that sustains stem cell activity during organ maintenance and regeneration.

167 duces aggression in mice, reduced DG granule cell activity during resident-intruder interactions.

168 Conversely, suppressing SST cell activity during the critical period prevents the no

169 The extent of NK cell activity during the innate immune response affects

170 In comparison, suppressing PV cell activity elevates the synchronization of spontaneou

171 I IFN is required for the induction of CD8 T cell activity following administration of R-DOTAP plus A

172 Local inhibition of Schwann cell activity following cutaneous sensory nerve transect

173 ated by these boundaries, by recording place cell activity from CA1 and CA3 while rats foraged on a c

174 is a potential target to improve cytotoxic T-cell activity.Grail is an E3 ubiquitin ligase that inhib

175 Subjects with low NK cell activity had a 10-fold higher risk of CRC compared

176 Electrical impedance-based sensing of cell activity has become a powerful analytical tool that

177 ABAergic neurotransmission sculpts principal cell activity in a relevant fashion.

178 enting support system is key to extending NK cell activity in a tumor environment.

179 ble stable measurement of neuronal and glial cell activity in behaving mice, we have developed fluore

180 xpression is associated with low cytolytic T-cell activity in both basal and classical PDA subtypes a

181 re has been little study of persistent glial cell activity in brains of athletes with sports-related

182 Because MHC-E is up-regulated to evade NK cell activity in cells infected with HIV, simian immunod

183 al (19)F probes can effectively track immune cell activity in combination with current MRI protocols.

184 riments in rats that measured place and grid cell activity in different environments, and then assess

185 ct signaling pathways that govern progenitor cell activity in homeostasis and disease.

186 We also uncover evidence of ramping cell activity in humans, which represents a complementar

187 These findings suggest that IgG(+) memory B cell activity in individuals with P. vivax strain-transc

188 the potential to prevent deregulated tissue cell activity in lung diseases that involve fibrosis and

189 preclinical proof-of-concept of NKG2D CAR T-cell activity in mouse glioma models and demonstrate eff

190 gnal that is involved in the control of stem-cell activity in plants grown under aerobic conditions,

191 indicating a protective role for normal stem cell activity in reducing myofiber strain associated wit

192 We propose that NOD coordinates cell activity in response to intrinsic and extrinsic cue

193 ent of Ag-specific T follicular helper (TFH) cell activity in rhesus macaques has not previously been

194 aling as an upstream factor controlling Treg cell activity in specific tissue environments.

195 role has evolved across animals according to cell activity in spite of cell identity.

196 KEY POINTS: The role of enteric glial cell activity in the acute regulation of epithelial barr

197 Here, we monitored cell activity in the anterodorsal thalamus (ADN), an are

198 These results suggest Purkinje cell activity in the cerebellar vermis regulates aggress

199 ce and immunopathology associated with CD8 T cell activity in the CNS.

200 ature cells de-differentiate to acquire stem cell activity in the face of injury.

201 rd optogenetically restored retinal ganglion cell activity in the fovea of the living primate.

202 and Blimp1 play dual roles in regulating Tfr-cell activity in the germinal center and in the developm

203 echniques to evaluate lysosomal function and cell activity in the model system and super-resolution m

204 Increasing Purkinje cell activity in the vermis significantly reduced the fr

205 eviates the suppression of tumour-specific T cell activity in vitro and in vivo.

206 erse immunomodulatory genes and suppressed T cell activity in vitro.

207 elop multispectral (19)F MRI to image immune cell activity in vivo using (19)F nanoparticles of two d

208 in shaping the rate and pattern of Purkinje cell activity in vivo.

209 opy as the reference standard, a test for NK cell activity in whole blood samples identified patients

210 thelial and mesenchymal phenotypes have stem cell activity, in many cells that have lost epithelial c

211 -characterized functions in controlling stem cell activity, including in the prostate.

212 mic activation of NRF2 suppresses effector T cell activities independently of Tregs and that NRF2 act

213 wever, oxidative stress is known to impair T cell activity, induce actin stiffness, and inhibit cell

214 l antibody production and antigen-presenting cell activity is a target of Treg suppression.

215 Precise regulation of stem cell activity is crucial for tissue homeostasis and nece

216 interference in vivo, we find that the Agrp cell activity is essential for ethanol-induced overeatin

217 Each single cell activity is expressed as current spikes decaying wi

218 mor immunogenicity, the negative impact on T-cell activity is functionally important.

219 xin-->D2 excitatory circuit and show that D2 cell activity is necessary for orexin-dependent innate r

220 applied EFs in conditions where control of T cell activity is paramount.

221 signals and eating, and demonstrate that OH cell activity is rapidly controllable, across nutritiona

222 hannel in beta-cells to understand how alpha-cell activity is regulated by beta-cells.

223 In vivo studies have shown that Golgi cell activity is regulated by climbing fiber stimulation

224 How B1 cell activity is regulated remains unclear.

225 Based on observation of place cell activity it is possible to accurately decode an ani

226 kemic cells endowed with leukemia-initiating cell activity (LIC).

227 The differential gene expression of cell activity marker (c-fos), early OPC (Olig1, Olig2.

228 Mast-cell activity may contribute to the pathogenesis of the

229 at immune modulators that block regulatory T cell activity may increase responses to viral attenuated

230 tic, in vitro data increasingly suggest that cell activity modulates vesicle content.

231 To maintain homeostasis, stem cell activity needs to be tightly controlled throughout

232 tory checkpoints in boosting the antitumor T cell activity of ICB nonresponders.

233 ntiation of postsynaptic layer 2/3 pyramidal cell activity of male, but not female, mice, thus produc

234 However, the direct influence of place cell activity on spatial navigation behavior has not yet

235 ry widely in strategies for facultative stem cell activity or interconversion among mature resident c

236 We now evaluated whether innate NK cell activity or PBMC transcriptional profiles were asso

237 h enables the analyses of individual granule cell activity over time and provides a powerful tool to

238 f pyramidal cells, thereby shaping pyramidal cell activity patterns.

239 We show that time cell activity predicts the temporal organization of retr

240 Interfering with T-cell activity prevented clearance of LMP-expressing B ce

241 s, sequences drifted to new populations with cell activity progressively converging to a field and th

242 gly, calcium recordings revealed that orexin cell activity rapidly reduced upon exiting the innately

243 dominantly reflect visual inputs, while grid cell activity reflects a greater influence of physical m

244 But whether glial cell activity regulates these functions acutely under ph

245 SpyCatcher T-cell activity relied upon the presence of both target an

246 t the motivational characteristics of orexin cell activity remain unclear.

247 from committed progenitor or mutipotent stem cell activity remains controversial.

248 activated IL-8 transcription and hepatic NK cell activity, respectively.

249 dforward sensory input to modulate principal cell activity selectively.

250 repetitive theta-frequency cycles of granule cell activity.SIGNIFICANCE STATEMENT Long-term synaptic

251 We studied this issue by recording cell activity simultaneously from dorsal premotor cortex

252 motor coordination were studied by recording cell activity simultaneously from the frontal cortex of

253 An early and persistent alteration of glial cell activity takes place at the neuromuscular junction

254 The NK cell activity test identified subjects with CRC with 87.

255 sphere capacity, criteria for assessing stem cell activity, than the Runx2-GFP(-) population.

256 intestinal tract is a site of intense immune cell activity that is poised to mount an effective respo

257 mossy fiber activity induces rhythmic Golgi cell activity that is synchronized by shared parallel fi

258 role for Foxp2 in the modulation of Purkinje cell activity that severely impacts skilled movements.

259 g small sequences of spatially related place-cell activity that we call "snippets".

260 and while the IL-27 heterodimer influences T cell activities, there is evidence that IL-27p28 can hav

261 Delta(9)-tetrahydrocannabinol depressed GABA cell activity, therefore downstream dopamine cells will

262 on, and as these compounds may dampen immune cell activity, this factor limits the conclusions that c

263 pensatory adaptations which stabilise target cell activity through activity-dependent global scaling

264 This often relies on repurposing cytotoxic T cell activity through modified T cell receptors or chime

265 In this study, we have observed single cell activity throughout the brains of larval zebrafish

266 escent center cells is thought to limit stem cell activity to directly neighboring cells, thus endowi

267 llance system in mammals constantly monitors cell activity to protect against aberrant proliferation

268 root meristem gradually transition from stem cell activity toward differentiation.

269 esting that DAC could positively modulate NK cell activity, trafficking, and tumor targeting.

270 APK and PI3K regulate dental epithelial stem cell activity, transit-amplifying cell proliferation, an

271 cylation decreases spontaneous CA3 pyramidal cell activity under basal and hyperexcitable conditions.

272 picture of how delta cells can modulate beta cell activity under physiological conditions.

273 However, imaging of neuronal cell activity under stable physiological conditions can

274 h following a burn injury requires satellite cell activity, underscoring the therapeutic potential of

275 Mx1(+) SCs possess potent stem cell activity upon transplantation but minimally contrib

276 or kappa-light-chain-enhancer of activated B cells) activity, VCAM, ICAM, and MCP1 levels in hyperten

277 S1P regulates diverse cell activities via S1P receptors (S1PRs).

278 T could replace patch clamps to study single cell activity via direct measurement in real time.

279 beta-cells triggered a suppression of alpha-cell activity via gap junction-dependent activation of d

280 cells, which suppresses natural killer (NK) cell activity via ligation of the NK inhibitory receptor

281 for detection of CRC in subjects with low NK cell activity vs subjects with higher NK cell activity w

282 NK cell activity vs subjects with higher NK cell activity was 10.3 (95% CI, 3.03-34.9).

283 Furthermore, during licking, stellate cell activity was anisotropic: the coordination was cons

284 cytokine synthesis, and pulmonary dendritic cell activity was assessed.

285 ited startles [8, 9], we hypothesized that M-cell activity was necessary for S-start generation.

286 Finally, low-magnitude gB-specific T cell activity was observed in the full-length gB protein

287 Single cell activity was recently shown to combine time and dis

288 in vitro-generated EBV-specific cytotoxic T cell activity was reduced because of CD70 deficiency.

289 Defective NK cell activity was shown to increase susceptibility for v

290 ate-limiting molecule for cytotoxic CD8(+) T cell activity, was evident in the lamina propria of sero

291 GF mice have a distinct Ig repertoire and B cell activity, we aimed to evaluate whether this altered

292 tention effects on narrow- and broad-spiking cell activity, we show that attention alters cortical st

293 and Neuropixels probe recordings of Purkinje cell activity, we show that climbing fibers signal rewar

294 ppressed CD8(+) T-cell responses, aberrant B-cell activities were maintained due to expression of CD4

295 was necessary to compromise adult islet beta-cell activity, which included whole-animal glucose intol

296 probes has shown an ability to track immune cell activity with a specific, stable, and quantitative

297 ense, including inhibition of natural killer cell activity with ongoing lowering of Ig levels and CMV

298 specific stromal composition could impact T-cell activity, with potential impact on the optimization

299 inhibition is directly linked to anti-cancer cell activity, with toxicophore modification ablating th

300 ts indicate that compounds that target mossy cell activity would be attractive candidates for the dev