ライフサイエンスコーパス: cell body

1 rojections normally returns cytoplasm to the cell body.

2 nals and/or signalling in the sensory neuron cell body.

3 nglement and ultimately fragmentation of the cell body.

4 s containing synaptic material mature in the cell body.

5 n the surrounding matrix directed toward the cell body.

6 tubules at distances far from the nucleus or cell body.

7 d accumulated hypophosphorylated NDK5 in the cell body.

8 an organelle that self-assembles outside the cell body.

9 ocation where the capsule is attached to the cell body.

10 h are delivered from the growing axon to the cell body.

11 ctivated gametes, aCRY is localized over the cell body.

12 d disc matching the dimensions of a neuron's cell body.

13 fusion barrier between the outer segment and cell body.

14 sulting in the compaction and removal of the cell body.

15 n within the three-dimensional volume of the cell body.

16 nd only later spreads to the oligodendrocyte cell body.

17 o the target neural element, whether axon or cell body.

18 greater cell force generation and a stiffer cell body.

19 rifugal propagation of Ca(2+) waves into the cell body.

20 anelles through lysosomal degradation in the cell body.

21 otoneuron while extending filopodia over the cell body.

22 ls arborize at a distance posterior to their cell body.

23 eir trailing edge retracting back toward the cell body.

24 tes signal transduction independent from the cell body.

25 appropriately engulf and cannibalize the PGC cell body.

26 ve resorption of ciliary components into the cell body.

27 nergetic flux rates than mitochondria in the cell body.

28 rade movement toward the distal end of the T cell body.

29 ens to hundreds of micrometers away from the cell body.

30 retrograde axonal transport to the neuronal cell bodies.

31 rade axonal transport after infection of the cell bodies.

32 truding the dendrites away from the neuronal cell bodies.

33 similar decrease in nerve fiber endings and cell bodies.

34 pairs, despite the regular spacing of their cell bodies.

35 to neuronal synapses, dendrites, axons, and cell bodies.

36 odendrocytes were swollen and had vacuolated cell bodies.

37 n-based contacts with neighboring mesodermal cell bodies.

38 endrites and clusters of their parent nigral cell bodies.

39 s a battery of injury responses in axons and cell bodies.

40 ticular mitochondria restricted to the motor cell bodies.

41 ensively in the squid giant axon than in its cell bodies.

42 GRP+ baskets) that enveloped myenteric nerve cell bodies.

43 rts at the synapses, then involves axons and cell bodies.

44 of AVP and OT-immunoreactive (ir) fibers and cell bodies across age and sex within the SBNN has been

45 How input from the cell body affects IFT and ciliary function is not well u

46 r for BDNF, deletion of Bdnf from cerebellar cell bodies alone did not perturb the localization of pr

47 ps did not vary with the position of the SIN cell body along the depth of the tectal neuropil or with

48 We highlight recent advances on how cell bodies and axons are instructed to either cross or

49 ed pluripotent stem cell (iPSC) motor neuron cell bodies and axons can be compartmentalized for indep

50 vidence that the activation of JNK by p75 in cell bodies and axons is required for internalization to

51 atiotemporal regulation of Nogo-A and NgR in cell bodies and axons of RGCs during ontogeny.

52 o TG neurons and expressed transgenes within cell bodies and axons of sensory neurons in all three br

53 re rapid and efficient communication between cell bodies and axons over long distances.

54 These include RGC dendrites, cell bodies and axons, the unmyelinated retinal nerve fi

55 sphorylated tau accumulates predominantly in cell bodies and axons.

56 In addition, abnormal positioning of Muller cell bodies and bipolar cells was evident throughout the

57 Because the cell bodies and central projections of these cochlear ne

58 als formed synapses with GFP-negative (host) cell bodies and dendrites and, unexpectedly, with some G

59 terial, opsins were found to be expressed in cell bodies and dendrites of cortical neurons and along

60 tic contacts with auditory efferent neuronal cell bodies and dendrites, as well as unlabeled axon ter

61 ASICs are localized to cell bodies and dendrites, including the postsynaptic de

62 rm layers, the sites of the retinal ganglion cell bodies and dendrites, respectively.

63 isoform (2N4R-Tau) was partially retained in cell bodies and dendrites, where it accelerated spine an

64 ion in nascent protein synthesis in neuronal cell bodies and dendrites.

65 Col4a3 mutants including distorted podocyte cell bodies and disorganized primary processes.

66 onset most likely exceeds that of the nigral cell bodies and has been estimated to be of the order of

67 of the peptidoglycan cell wall of stalks and cell bodies and identified key differences in peptidogly

68 lly expressed Channelrhodopsin (ChR2) in CST cell bodies and in axon terminals in cervical spinal cor

69 1 antibodies were found to surround neuronal cell bodies and interact with CD68(+) immune cells via F

70 ntified an interaction site between neuronal cell bodies and microglial processes in mouse and human

71 alances microglial association with neuronal cell bodies and myelin phagocytosis in the optic tectum.

72 az also promoted the scavenging of apoptotic cell bodies and necrotic debris by PDA cells.

73 lar matrix but could also be observed within cell bodies and neurites as well as within the endotheli

74 expression and translation rates in isolated cell bodies and neurites genome-wide.

75 teome, and translated transcriptome in their cell bodies and neurites, providing a unique resource fo

76 tive regeneration, fewer cells, larger basal cell bodies and nuclei, paradoxical increases in prolife

77 scence intensities of PV immunoreactivity in cell bodies and of WFA labeling and aggrecan immunoreact

78 ntous microprojections arising from podocyte cell bodies and processes, and presence of unique bridgi

79 rritories with inhibitory inputs enriched on cell bodies and proximal dendrites and excitatory inputs

80 ted that unprocessed pro-NRG2 accumulates on cell bodies and proximal dendrites, and that NMDAR activ

81 Image analysis tools automate detection of cell bodies and quantification of axon density labeling

82 brain, but PDF expression persists in their cell bodies and remaining projections.

83 The effect is observed with cell bodies and small neurites rather than their process

84 o topographic maps in which the positions of cell bodies and synaptic targets correspond.

85 nnel-mediated calcium responses, both in the cell bodies and the intact peripheral endings of nocicep

86 ists in sLNvand large ventral lateral neuron cell bodies and their remaining projections.

87 synapses can be different from those in the cell bodies and, consequently, qualitatively different c

88 large illumination spot covering the entire cell body and an amplified laser at high peak power and

89 ), which extend tens of micrometers from the cell body and are distinct from filopodia.

90 sive changes in distribution of mRNAs in the cell body and axon compartments of peripheral sensory ne

91 r, while GnRH was expressed in both neuronal cell body and axons in the hypothalamus of 4.1N(+/+) mic

92 bone morphogenetic protein receptors in the cell body and correlates with increased synaptic growth.

93 ellular matrix molecules, which surround the cell body and dendrites of many types of neuron and regu

94 f 1,142 RGCs in 26 retinas take into account cell body and dendritic field size, level(s) of dendriti

95 This accumulation involved the entire cell body and distal processes of oligodendrocytes, but

96 number of pili and their distribution on the cell body and environmental factors such as flow and sur

97 d morphology characterized by a more rounded cell body and fewer dendrites than wild-type cells.

98 abilities of the hook protein connecting the cell body and flagellum play a role in locomotion.

99 and the rotational degrees of freedom of the cell body and flagellum, and we use numerical simulation

100 The filaments gather behind the cell body and form a close helical bundle, which propels

101 es to isolate signals in the cilium from the cell body and neighboring cells.

102 Instead, movement of the cell body and nucleus (nucleokinesis) is disrupted.

103 beating was estimated from the motion of the cell body and of the cilium.

104 rhodopsin1-containing vesicles (RLVs) in the cell body and reduced rhodopsin protein.

105 we show that Piezo2 channels, present in the cell body and terminals of corneal neurons, are directly

106 ing due to gas leaks at the interface of the cell body and the rotator.

107 number of flagella, their arrangement on the cell body and their sense of rotation hypothetically det

108 d by stimuli at their hair bundles drive the cell body and, in turn, it has been assumed, amplifies t

109 t-derived synapses on GFP-immunoreactive MGE cells bodies and dendrites.

110 tinal drusenoid deposits and drusen, (2) RPE cell bodies, and (3) the choriocapillaris' vascular dens

111 es with enlarged cell components (dendrites, cell bodies, and nuclei) or by epithelioid melanocytes w

112 olds surrounded unmyelinated axons, neuronal cell bodies, and other myelin profiles.

113 NRG2, accumulate as unprocessed proforms on cell bodies, and their ectodomains are shed by metallopr

114 distributed in the nucleus, cytoplasm of the cell body, and axon.

115 Rab7-positive tubulated compartments in the cell body, and concomitant depletion of SNX16-positive e

116 mbrane, detachment of the flagellum from the cell body, and disruption of mitotic spindles.

117 alization of ATP8A2 to the inner segment and cell body, and increased apoptosis in the retina.

118 tion in the outer segment, metabolism in the cell body, and neurotransmitter release at the synaptic

119 slocalized along the microtubules to the IS, cell body, and synaptic region.

120 ns have distinct roles in the outer segment, cell body, and synaptic terminal of photoreceptors.

121 llowing retrograde transport to the cortical cell bodies, apoptosis was induced by infrared laser ill

122 Neuronal cell bodies are captured from perfused mouse brain slice

123 gans are innervated by sensory neurons whose cell bodies are located in multiple ganglia associated w

124 Vesicles formed in the cell body are actively transported by kinesin motors alo

125 he interneuron, based on the position of the cell body, ascending axon, dendritic arborization patter

126 nt loss of VGLUT1 terminals on dendrites and cell bodies at both 21 days and 3 months post-crush.

127 orithm, we found that the highest density of cell bodies at both spinal levels could be found in the

128 into the synaptic neuropil and anchoring of cell bodies at the neuropil border.

129 rate that microtubule nucleation outside the cell body at Golgi outposts by TPPP is critical for elon

130 the cochlea have a unique motility in their cell body based on mechanoelectric coupling, with which

131 These proteins originate from the cell body because cilia lack protein synthesis machinery

132 4.1N(+/+) mice, it was only expressed in the cell body but not the axons of 4.1N(-/-) mice.

133 s degenerate following separation from their cell body, but partial injury to peripheral nerves may l

134 ent of ligand surface density underneath the cell body by constantly rupturing local ligands, and the

135 In neuronal cell bodies, CAR-1 fully colocalizes with CGH-1 and part

136 rease in synaptic coverage around motoneuron cell bodies compared with short-term data, which is indi

137 ercoiled 'endoflagella' that wrap around the cell body, confined within the periplasmic space.

138 ependent node-and-cable actin network in the cell body cortex.

139 found that photoactivation of PPTg glutamate cell bodies could serve as a direct positive reinforcer

140 ype I neurites, followed by type II neuronal cell-body degeneration.

141 ermined that autophagosome maturation in the cell body depends on the protease ATG-4.2, but not the r

142 eceptor kinase A expression and assessed for cell body diameter, population size, apoptotic markers,

143 d, the frequency and function of retrograde (cell body directed) mitochondrial transport in neurons a

144 ourteen neuron subtypes, many showing biased cell body distributions across the DR.

145 , the intercalation of post-mitotic neuronal cell bodies during VNC formation.

146 idirectional manipulation of PPN cholinergic cell bodies exerted opposing effects on locomotor behavi

147 mulation of VTA or substantia nigra dopamine cell bodies failed to induce food approach or eating.

148 re-modelling process involves an increase in cell body, flagellum and flagellum attachment zone lengt

149 that dopamine neurons secrete IGF-1 from the cell bodies following depolarization, and that IGF-1 con

150 rsal root ganglia (DRG), the primary sensory cell body for peripheral nerve injury generated hypersen

151 s, macropinosomes encapsulate F-actin in the cell body, forming vesicles that translocate via microtu

152 on, adhering to an ECM node, and pulling the cell body forward) and 'rear-squeezing' (pushing the cel

153 hear forces that are sufficient to drive the cell body forwards.

154 d to separate the mechanical response of the cell body from deformation of the pericellular layer sur

155 , phagocytic clearance of dead photoreceptor cell bodies has a protective role by preventing addition

156 tin protein at the growth cone even when the cell bodies have been removed.

157 gy analysis, we document marked variation in cell body helical parameters and flagellum number among

158 the buildup of synaptic proteins in neuronal cell bodies, hence may play an adaptive role to stresses

159 erefore quantified AVP- and OT-ir fibers and cell bodies in 22 subregions of the forebrain SBNN in ju

160 fferences in OT-ir fiber fractional areas or cell bodies in any of the 22 subregions of the forebrain

161 We found a reduction of NeuN(+) neuronal cell bodies in areas of the ventral gray matter of the s

162 ial roles for glial ensheathment of neuronal cell bodies in CNS homeostasis as well as Spz3 as a nove

163 n axis, is via spinal afferent neurons, with cell bodies in dorsal root ganglia (DRG).

164 neurofibrillary tangles observed in neuronal cell bodies in individuals with Alzheimer's disease.

165 d apical tuft dendrites and their respective cell bodies in retrosplenial cortex, an area that encode

166 Inhibition of cell bodies in SNpr suppressed generalized seizures evok

167 responsive olfactory projection neurons with cell bodies in the AL lateral cell cluster (MGC lcPNs) o

168 e exception of the unique presence of RFRP-3 cell bodies in the arcuate nucleus (Arc).

169 the solitary tract (NTS), and activation of cell bodies in the central amygdala (CeA) or axons in th

170 arrestin-1 moves from the inner segments and cell bodies in the dark to the outer segments in the lig

171 ring of calcium transients in ~1000 neuronal cell bodies in the ganglia during tracheal perfusion wit

172 well as a putative amacrine cell with their cell bodies in the inner nuclear layer (INL) and a dense

173 pheromone-responsive projection neurons with cell bodies in the moth medial cell cluster (mcPNs) pred

174 ographic maps, where the positions of neuron cell bodies in the projecting field correspond with the

175 e observed in ex vivo vagus nerve and neuron cell bodies in the vagal ganglia.

176 by stimulation of LH GABA terminals or GABA cell bodies in this peri-LC region.

177 trograde tracing showed that these clustered cell bodies in turn project to the striatum as part of t

178 endritic arborization and mislocalization of cell bodies in vivo These cellular defects were associat

179 nto a spiral-like form that wraps around the cell body in a spiral-like fashion and enables the cell

180 ing evidence points to a requirement for the cell body in the degenerative program.

181 retrogradely transported to the motor neuron cell body in the spinal cord, recycled to the plasma mem

182 RNP A1 antibodies were found within neuronal cell bodies including those of the ventral spinocerebell

183 ncluded loss of glial ensheathment of neuron cell bodies, increased neuronal cell death, and defects

184 served extending from podocyte processes and cell body, indicating significant membrane dynamics acco

185 like structures surrounding individual nerve cell bodies innervating the spleen.

186 Approximately half (48%) of nerve cell bodies inside CGRP+ baskets lacked both NOS and CAL

187 al dendrite and a novel pathway in which the cell body integrates proximal synaptic inputs, leading t

188 In cell bodies, internalization of p75 required the activit

189 ansport of nascent HSV particles from neuron cell bodies into axons and along axons to axon tips in t

190 particularly important for moving DCVs from cell bodies into axons, and then Unc-104 and kinesin-1 f

191 The C-terminal fragment localizes to the cell body irrespective of INF2 mutations.

192 Under the subheading 'Spiking of L5 cell bodies is not influenced by spindles', the first se

193 onal contacts, but how glia support neuronal cell bodies is unclear.

194 ptotic machinery being present in axons, the cell body is an active participant in gating axonal casp

195 Orientation of the flagella toward the cell body is critical for determination of wild-type spi

196 ed since the resulting feeding flow past the cell body is stronger, leading to a higher clearance rat

197 These data indicate that the cell body is the focus of Parkin-dependent mitochondrial

198 e detected by spinal afferent neurons, whose cell bodies lie in dorsal root ganglia (DRGs).

199 is provided by spinal afferent nerves, whose cell bodies lie predominantly in thoracolumbar dorsal ro

200 ays; and is often associated with a pericyte cell body located off vessel.

201 ogical deficits, axonal degeneration without cell body loss, and cytoplasmic and axonal accumulations

202 d dentate gyrus, with no frank noradrenergic cell body loss.

203 anied by decreased epidermal innervation and cell-body loss in the dorsal root ganglia.

204 cal applications require the segmentation of cell bodies, membranes and nuclei from microscopy images

205 ged organelles in axon terminals and loss of cell body mitochondria.

206 type: young postmitotic neurons have smaller cell bodies, more extensively branched neurites, and red

207 in AVP-ir fiber fractional areas, and AVP-ir cell body numbers, which were mainly observed in the med

208 ord, KChIP1 is coexpressed with Kv4.3 in the cell bodies of a subset of lamina II excitatory interneu

209 tructures appear to surround synapses on the cell bodies of a subset of the neurons in the central ne

210 d-type mice, Muller glial cells phagocytosed cell bodies of dead rod photoreceptors albeit at a lower

211 ure and dynamics of neural circuits, but the cell bodies of individual neurons are often obscured by

212 Satellite glial cells (SGCs) closely envelop cell bodies of neurons in sensory, sympathetic and paras

213 nal population are densely intermingled with cell bodies of others.

214 The dorsal root ganglia (DRG) contain cell bodies of primary afferent neurons, which are frequ

215 By physically dissecting projections from cell bodies of primary rat hippocampal neurons and seque

216 C were inferred to be excitatory because the cell bodies of retrogradely labeled neurons did not cola

217 Dorsal raphe (DR) harbors cell bodies of serotonin-producing neurons that supply s

218 Although the location of the nerve cell bodies of spinal afferents is well known to reside

219 mutated versions of DAT were confined to the cell bodies of the dopaminergic neurons in the fly brain

220 ise from reactivated latent virus in sensory cell bodies of the dorsal root ganglia (DRG).

221 SN that was not present in the corresponding cell bodies of the DRG or the cranial TG.

222 ved in processes, varicosities, and neuronal cell bodies of the olfactory bulb, granular zones of cor

223 kably, the same relationship is not found in cell bodies of the same neurons and throughout the corti

224 Cell bodies of these neurons were located in 11 differen

225 While the origin of the cell bodies of uterine spinal afferents is clear, the id

226 ed expression of this opsin primarily to the cell body of mammalian cortical neurons.

227 that localized GCaMP to within 50 mum of the cell body of neurons in mice and larval zebrafish.

228 nal, optogenetic activation of VTA glutamate cell bodies or axon terminals in NAc was sufficient to s

229 a(2+) when it accumulates either in the cone cell body or outer segment.

230 ck activity in large populations of neuronal cell bodies, or to follow dynamics in subcellular compar

231 ents studied (ie, extracellular [p = 0.001], cell body [p = 0.003], and neuritic/glial-processes [p =

232 Cell body peptidoglycan contained primarily DD-crosslink

233 dpf spinal cord demonstrates variable dmrt3 cell body position and dimensions, confirmed by single c

234 Using independent features such as cell body position, axon projections and lipophilic dye

235 ells with respect to their birthplace, final cell body position, axonal trajectory, and neurotransmit

236 pheric growth cones relative to their parent cell bodies, producing paired subcellular proteomes and

237 Here we show that DRG neuron cell bodies release extracellular vesicles, including ex

238 Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia.

239 Accumulation of alpha-syn at the cell body resulted in aberrant association with cis-Golg

240 long microtubules from axon tips to neuronal cell bodies (retrograde transport) or from cell bodies t

241 We also found that VTA cell bodies retrogradely labeled from the various target

242 were located in 11 different clusters in the cell body rind.

243 Axonal and cell body RNA samples were separately subjected to high

244 ree clusters of TRN neurons that differed in cell body shape and size, dendritic arborization pattern

245 essite can be reduced up to 15 mum away from cell bodies, similar to the reported length of Geobacter

246 r kinase A-positive neurons showed a reduced cell body size (atrophy) and decreased population size (

247 C1) hyperactivation and associated increased cell body size and process outgrowth, as well as exacerb

248 morphological state, by exhibiting expanded cell body size and retracted processes.

249 p-/m+ mice, reduced primary forebrain neuron cell body size is apparent in embryonic day 15.5 fetuses

250 Snord116p-/m+ mice the reduction in neuronal cell body size was associated with decreased neuronal nu

251 tive neuronal subpopulations, based on their cell body size.

252 require spatial input; the majority of their cell bodies subsequently move to cover the entire medull

253 creased microglia coverage of the motoneuron cell body surface with time after injury and the presenc

254 ne dye (DiI) revealed that many of the nerve cell bodies surrounded by calbindin baskets belong to mo

255 We address this problem by engineering cell-body-targeted variants of the fluorescent calcium i

256 In the brain, compact clusters of neuron cell bodies, termed nuclei, are essential for maintainin

257 nds creates an ECM ligand gradient below the cell body that guides cellular migration.

258 rved in both pyramidal cells and interneuron cell bodies, the low-frequency content of membrane fluct

259 the filopodial shaft and surfing toward the cell body, the most common mode of capture; (ii) capturi

260 rogradely transported for degradation in the cell body, the precise impact of disrupting retrograde t

261 ered nanobody can be used to trap GFP in the cell body, thereby enabling direct visualization of prev

262 t with the cerebrospinal fluid through their cell bodies, they send processes into the arcuate nucleu

263 erve-ending loss occurs before a decrease in cell bodies; this phenotype is indicative of axonal dieb

264 e Ca(2+) waves increase RhoA activity in the cell body through calcium/calmodulin-dependent protein k

265 y forward) and 'rear-squeezing' (pushing the cell body through the ECM by contracting the cell cortex

266 The third step is migration of the tumor cell body through the remodeled matrix.

267 transporting mitochondria from the neuronal cell body throughout the bundles of DRG axons.

268 l cell bodies (retrograde transport) or from cell bodies to axon tips (anterograde transport).

269 llows only healthy mitochondria to pass from cell bodies to axons, perhaps to limit the impact of mit

270 rogradely transported from axon terminals to cell bodies to induce cell death.

271 ng, neurons of distinct types localize their cell bodies to just one or a few of the layers within a

272 how severed distal axons signal back to the cell body to induce hyperexcitability, loss of inhibitio

273 haracterization of the helical motion of the cell body to lift the 2D data to 3D trajectories.

274 lity, i.e., the ability of their cylindrical cell body to shorten and elongate upon cell depolarizati

275 h associate almost exclusively with neuronal cell bodies) to understand glia-soma interactions.

276 t of the displacement and orientation of the cell body together with a description of the movement of

277 semblies known as neuronal granules from the cell body toward synaptic regions.

278 waves, which stochastically migrate from the cell body towards neurite tips, direct microtubule-based

279 y scale morphology filter and the removal of cell bodies using a high intensity mask.

280 eover, localization of aCRY within the algal cell body varies between vegetative cells and the differ

281 rograde pro-degenerative signals to neuronal cell bodies via its downstream target c-Jun N-terminal k

282 uclei, which averages 41.9% and 49.2% of the cell body volume, respectively, but that in turn the com

283 uidically and physically separate axons from cell bodies, we found that the proteasomal degradation o

284 etter differentiate axons and dendrites from cell bodies, we mapped the tissue in terms of its scatte

285 um-dependent potassium channels found at the cell body, we show here that calcium-dependent potassium

286 e in the inner nuclear layer (INL) and a few cell bodies were in the ganglion cell layer (GCL).

287 ajority of tdTomato and Confetti fluorescent cell bodies were in the inner nuclear layer (INL) and a

288 fied as "simple-type." Rarely, uterine nerve cell bodies were labeled in nodose ganglia.

289 No NPY- or Npy-expressing cell bodies were observed in the VTA.

290 In contrast, in the cerebellum, the Purkinje cell bodies were the most strongly immunolabeled element

291 Labeled terminals, but not cell bodies, were observed in the nucleus lateralis valv

292 in signaling endosomes from distal axons to cell bodies, where they are inserted on soma surfaces an

293 ral RB neurons arborize in the skin near the cell body whereas caudal cells arborize at a distance po

294 their rapidly growing plus end away from the cell body, whereas in vertebrate dendrites, their orient

295 ith minus-end-out are transported toward the cell body while "correctly" oriented MTs are transported

296 (PM) contacts were particularly abundant in cell bodies, with large, flat ER cisternae apposed to th

297 peptidoglycan incorporation occurs along the cell body, with the notable exception of a large region

298 ddress this gap, we optogenetically silenced cell bodies within SNpr, nigrotectal terminals within DL

299 s in olfactory bulb glomeruli as well as OSN cell bodies within the olfactory epithelium in freely br

300 urofascin leads to mistargeting of myelin to cell bodies, without affecting targeting to axons.

301 Lastly, TIDA neuron stimulation at the cell body yielded perisomatic release of dopamine, which