ライフサイエンスコーパス: cell cycle arrest

1 Complexes 1 and 3 induce predominant G1 cell cycle arrest.

2 lin complexes (e.g., Cdk2/cyclin A), causing cell cycle arrest.

3 er ERR-betasf isoform in senescence and G(1) cell cycle arrest.

4 growth suppression is likely attributed to a cell cycle arrest.

5 sient stalling or a prolonged but reversible cell cycle arrest.

6 lved in responding to TGF-beta signaling and cell cycle arrest.

7 endent compensation of the miR-29b effect on cell cycle arrest.

8 y CDK6 protein down-regulation and G(0)-G(1) cell cycle arrest.

9 independent growth of ILC cell lines through cell cycle arrest.

10 ibits HNSCC growth by inducing apoptosis and cell cycle arrest.

11 of protection against oxidative stress, and cell cycle arrest.

12 ation that leads to extensive DNA damage and cell cycle arrest.

13 which lead to premature differentiation and cell cycle arrest.

14 isruption of the nucleolus, and consequently cell cycle arrest.

15 vely, leading to activation of p21(CIP1) and cell cycle arrest.

16 ces HIV-1 gene expression and induces (G2/M) cell cycle arrest.

17 ing cell proliferation through initiation of cell cycle arrest.

18 , HKL decreased CDK2 activity, leading to G1 cell cycle arrest.

19 tion fork, causing replicative stress and/or cell cycle arrest.

20 of tubulin polymerization, and induction of cell cycle arrest.

21 s of hUPF1 induces a DNA damage response and cell cycle arrest.

22 eads to suppression of protein synthesis and cell cycle arrest.

23 by which p53 can enforce and maintain a G2/M cell cycle arrest.

24 impeded actin dynamics, cell spreading, and cell cycle arrest.

25 -mediated HLTF degradation or Vpr-induced G2 cell cycle arrest.

26 proliferation by promoting apoptosis not by cell cycle arrest.

27 curs in dividing cells and is independent of cell cycle arrest.

28 ion to repair functions for this protein and cell cycle arrest.

29 4, resulting in its nuclear localization and cell cycle arrest.

30 essary and sufficient for Vif-dependent G2/M cell cycle arrest.

31 CHK(1/2)-CDC25A-cyclin A/E pathway to induce cell cycle arrest.

32 nd shutdown of mitotic kinases, resulting in cell cycle arrest.

33 n of BRF1 reduced proliferation and mediated cell cycle arrest.

34 gered by transient Snt1 phosphorylation upon cell cycle arrest.

35 , but increases DNA damage over time causing cell cycle arrest.

36 malignant phenotypes of colorectal tumor by cell cycle arrest.

37 nstability and allows mcm4-dg cells to evade cell cycle arrest.

38 sory protein is also known to trigger G(2)/M cell cycle arrest.

39 stly attributable to postnatal cardiomyocyte cell cycle arrest.

40 the phosphorylation of H2AX and induced G2/M cell cycle arrest.

41 ve to oxidative stress due to the defects in cell cycle arrest.

42 isions, including apoptosis, senescence, and cell cycle arrest.

43 e, K. pneumoniae 51-5 induces DNA damage and cell cycle arrest.

44 KF) triggered caspace-mediated apoptosis and cell cycle arrest.

45 cells in different cell-cycle phases and in cell-cycle arrest.

46 in-3A, which otherwise predominantly induced cell-cycle arrest.

47 ination of two processes: cell expansion and cell-cycle arrest.

48 nd is frequently referred to as irreversible cell-cycle arrest.

49 and DREAM on p53-induced gene repression and cell-cycle arrest.

50 ere refractory to MEKi killing and augmented cell-cycle arrest.

51 It also induced G(2)/M cell-cycle arrest.

52 crease as telomeres shorten, which all favor cell-cycle arrest.

53 ional target genes that induce apoptosis and cell-cycle arrest.

54 lication fork recovery, and enforcing a G2/M cell-cycle arrest.

55 on promoted epithelial dedifferentiation and cell-cycle arrest.

56 iability through caspase activation and G2/M cell-cycle arrest.

57 A may be targeted for demethylation when the cell cycle arrests.

58 i shortly after birth and mediates postnatal cell cycle arrest(3).

59 palbociclib plus letrozole achieved complete cell-cycle arrest (90% v 59%; P < .001).

60 s for investigation of type of cell death or cell cycle arrest a flow cytometric analysis was applied

61 liferation and colony formation, and induced cell cycle arrest accompanied by increased expression of

62 liferation and colony formation, and induced cell cycle arrest along with suppression of migration an

63 ells are maintained in a state of reversible cell cycle arrest, also called quiescence.

64 Senescence is characterized by a stable cell cycle arrest and a complex proinflammatory secretom

65 ether the mechanisms controlling endothelial cell cycle arrest and acquisition of specialized phenoty

66 aled that chemotherapy induced activation of cell cycle arrest and apoptosis genes were attenuated in

67 impact ERK signaling dynamics and to induce cell cycle arrest and apoptosis in ERK-dependent cancers

68 receptor, integrin-beta1, to inhibit tubular cell cycle arrest and apoptosis in in vivo and in vitro

69 We found that Neat1 is dispensable for cell cycle arrest and apoptosis in response to genotoxic

70 el of cellular cAMP has been shown to induce cell cycle arrest and apoptosis in TNBC cells.

71 tively decreased the viability, promoted the cell cycle arrest and apoptosis of human EVI1-positive c

72 t induces non-small cell lung cancer (NSCLC) cell cycle arrest and apoptosis via restoring p53 expres

73 of cell death mechanism showed a mixture of cell cycle arrest and apoptosis was responsible for the

74 the IL-17 receptor, activated FRCs underwent cell cycle arrest and apoptosis, accompanied by signs of

75 tumor cell lines, and concomitantly induces cell cycle arrest and apoptosis, thereby impairing proli

76 omal protein L3 (uL3) may affect DNA repair, cell cycle arrest and apoptosis.

77 hich respond to OGT inhibition by undergoing cell cycle arrest and apoptosis.

78 ificant synergism was observed, resulting in cell cycle arrest and apoptosis.

79 suppresses microtubule dynamics and leads to cell cycle arrest and apoptosis.

80 sociated with proliferation, thus preventing cell cycle arrest and apoptosis.

81 e DNA damage response, impacting DNA repair, cell cycle arrest and apoptosis.

82 5 strongly induced squamous differentiation, cell cycle arrest and apoptosis.

83 esistant EOC cells through induction of G2/M cell cycle arrest and apoptotic cell death.

84 PSMB6, which together induces autophagy and cell cycle arrest and benefits virus replication.

85 induced apoptosis, differentiation and G2/M cell cycle arrest and caused less undesirable stabilizat

86 TAT1 and suppresses interferon (IFN) induced cell cycle arrest and cell apoptosis.

87 n of MSC2504877 to palbociclib enhances G(1) cell cycle arrest and cellular senescence in tumour cell

88 on of DNA double-strand breaks (DSBs), G0/G1 cell cycle arrest and cellular senescence.

89 any genes in U2OS cells, consistent with the cell cycle arrest and changes to ALT markers, but these

90 reatment with this enzyme selectively causes cell cycle arrest and death in cancer cells due to deple

91 leads to a lack of responsiveness to IGF-1, cell cycle arrest and decreased viability of cancer cell

92 UV-induced PAF also activates cell cycle arrest and disrupts DNA repair, in part by in

93 more, we provide molecular evidence that the cell cycle arrest and DNA binding activities of IE2 appe

94 While genes related to cell cycle arrest and DNA damage responses are mostly mo

95 s that express the wild-type p53, leading to cell cycle arrest and growth inhibition.

96 e ERR-beta2 isoform to play a role in G(2)/M cell cycle arrest and induction of apoptosis, in contras

97 albociclib decreases PASMC proliferation via cell cycle arrest and interference with the downstream C

98 and B16F10 cell proliferation, induced G2/M cell cycle arrest and led to apoptosis and cell death.

99 TR and CHK1 to 53BP1 damage foci, abrogating cell cycle arrest and permitting progression into S-phas

100 Senescent cells undergo a stable cell cycle arrest and produce a bioactive secretome that

101 upon glutamine deprivation, thus triggering cell cycle arrest and promoting cell survival.

102 amage response, a signaling cascade allowing cell cycle arrest and repair of lesions.

103 NA damage in IGF-1R-negative cells caused G1 cell cycle arrest and S phase fork stalling.

104 a subset of cells, which was accompanied by cell cycle arrest and senescence in several melanoma cel

105 i withdrawal drives a p57(KIP2)-dependent G1 cell cycle arrest and senescence or expression of NOXA a

106 This hyperfusion causes cell cycle arrest and subsequent inhibition of cell prol

107 kdown of FEN1 resulted in G1/S or G2/M phase cell cycle arrest and suppressed in vitro cellular proli

108 confirmed by protein modulation, leading to cell cycle arrest and survival benefit in vivo.

109 s a stress response that elicits a permanent cell cycle arrest and triggers profound phenotypic chang

110 is a transcriptional repressor implicated in cell cycle arrest and whose repressive activity depends

111 vivo as a microtubule disruptor, leading to cell cycle arrest and with both proapoptotic and anti-an

112 eration was strongly reduced by induction of cell cycle arrest and, to some extent, cell death.

113 ouble-strand breaks in MSI cells, leading to cell cycle arrest and/or apoptosis.

114 llular senescence is characterized by stable cell-cycle arrest and a secretory program that modulates

115 hibition of mTOR signaling, and induction of cell-cycle arrest and apoptosis in cancer cells.

116 * blocked cell growth leading to G0-G1 phase cell-cycle arrest and apoptosis in colorectal cancer cel

117 ration in Burkitt lymphoma, but also induces cell-cycle arrest and apoptosis mediated by p53, a tumor

118 provided resistance to dexamethasone-induced cell-cycle arrest and apoptosis, illuminating a new poss

119 pathway inhibits proliferation and promotes cell-cycle arrest and apoptosis.

120 ell proliferation/viability and by promoting cell-cycle arrest and apoptosis.

121 and activation of its targets, resulting in cell-cycle arrest and apoptosis.

122 cts in multiple cancer cell lines and induce cell-cycle arrest and apoptosis.

123 MYCN-amplified neuroblastoma cells, causing cell-cycle arrest and autophagy.

124 proliferation, clonogenicity, induced G(2)/M cell-cycle arrest and caspase-mediated-apoptosis of CRC

125 so mouse and human cells from stress-induced cell-cycle arrest and cell death in a polymer length-dep

126 itor, p21(Waf1/Cip1), which further leads to cell-cycle arrest and decreased cell viability.

127 The DDR culminates in either transient cell-cycle arrest and DNA repair or elimination of damag

128 Our findings indicate that Vpr promotes cell-cycle arrest and HIV-1 gene expression through depl

129 cultures, Mif deletion led to enhanced G2/M cell-cycle arrest and increased expression of the CDK in

130 tive potential correlates with cardiomyocyte cell-cycle arrest and polyploidization as well as the de

131 atal development when cardiomyocytes undergo cell-cycle arrest and polyploidization.

132 is a central tumor suppressor, which induces cell-cycle arrest and senescence.

133 e latter mechanism involves p38-dependent G1 cell-cycle arrest and subsequent intrinsic mitochondrial

134 in a cell-cycle-dependent manner, leading to cell-cycle arrest and the promotion of DNA repair.

135 c large-cell lymphoma cell lines by inducing cell-cycle arrest and/or apoptosis.

136 Monensin (10 nM) induced apoptosis, cell cycle arrest, and an increase in reactive oxygen sp

137 6OTD caused DNA damage, G1 cell cycle arrest, and apoptosis in GSCs but not in NSGC

138 ocesses, such as differentiation, migration, cell cycle arrest, and apoptosis, during developmental o

139 lular proteins to cause translation shutoff, cell cycle arrest, and autophagosome formation, all of w

140 s DNA damage, checkpoint activation, S-phase cell cycle arrest, and cell death in sensitive breast ca

141 Physiologically, DJ34 induced apoptosis, cell cycle arrest, and cell differentiation.

142 sis, abolished cytarabine-induced S and G2/M cell cycle arrest, and cooperated with cytarabine in ind

143 volume with increased mitofusin, markers of cell cycle arrest, and decreased parkin expression.

144 ppresses tumor growth by inducing apoptosis, cell cycle arrest, and DNA damage and inhibits protein p

145 cluding cellular differentiation, apoptosis, cell cycle arrest, and DNA damage.

146 e proliferation of these cells, induced G2/M cell cycle arrest, and led to apoptosis.

147 nes resulted in DNA damage response, S-phase cell cycle arrest, and reduction in cell growth.

148 if activation/expression, dedifferentiation, cell cycle arrest, and renal fibrogenesis evident in veh

149 hondrial DNA damage, leading to irreversible cell cycle arrest, and secretion of proinflammatory cyto

150 cancer cells by inducing both apoptosis and cell cycle arrest, and that reducing DHX33 levels throug

151 Corin treatment induces cell death, cell-cycle arrest, and a cellular differentiation phenot

152 MDM4 knockdown activated p53, induced cell-cycle arrest, and decreased tumor growth in a xenog

153 ture of antigen processing and presentation, cell-cycle arrest, and execution phase of apoptosis on t

154 compounds induce significant PEL apoptosis, cell-cycle arrest, and intracellular ceramide production

155 and longevity by minimizing apoptosis, G2/M cell-cycle arrest, and subsequent fibrosis.

156 nhibition significantly increased apoptosis, cell-cycle arrest, and tumor immunogenicity and generate

157 ficantly reduced cellular growth and induced cell cycle arrest, apoptosis of ATC cells by altering th

158 rge panel of biological processes, including cell cycle arrest, apoptosis, or senescence.

159 At low passage NPCs (P1 to P3), we observed cell cycle arrest, apoptosis, progressive change to a gl

160 Treatment of GIST cells with BBIs led to cell-cycle arrest, apoptosis, and cell death, with uniqu

161 and inactivates CRLs and, in turn, triggers cell-cycle arrest, apoptosis, senescence and autophagy i

162 ploit the cross-talk of signals activated by cell-cycle arrest, as well as pediatric-focused drug dev

163 th MEVB decreased cell viability and induced cell cycle arrest at G(1) phase and apoptosis.

164 T1-KD) cells showed reduced growth rates and cell cycle arrest at G(2)/M.

165 H-SY5Y cells with PMA and it correlated with cell cycle arrest at G2/M, upregulation of tumor suppres

166 n and invasion as well as in vitro growth by cell cycle arrest at S phase with increased cell size an

167 ited osteosarcoma cell proliferation, led to cell cycle arrest at S phase, and decreased colony forma

168 e found that overexpression of ABHD5 induces cell cycle arrest at the G1 phase and causes growth reta

169 ynergistic apoptosis and necrosis along with cell cycle arrest at the G1-S phase and elicits anti-ang

170 ma (RB) protein phosphorylation and inducing cell cycle arrest at the G1/S phase transition.

171 s induced an antiproliferative response with cell cycle arrest at the G2/M phase.

172 d responses in a dose-dependent manner, from cell-cycle arrest at low nanomolar concentrations to cel

173 found that treatment with 9-ING-41 leads to cell cycle arrest, autophagy and apoptosis in bladder ca

174 cell proliferation and survival by inducing cell cycle arrest, autophagy, DNA repair, and inhibition

175 n addition, Nutlin-3 increased apoptosis and cell cycle arrest based on flow cytometry assays.

176 The recent development of cell cycle arrest biomarkers that signal the potential d

177 We hypothesized that the product of the G1-cell cycle arrest biomarkers tissue inhibitor of metallo

178 Cell cycle arrest biomarkers, TIMP-2 and IGFBP7, improve

179 Loss of SAHFs does not affect cell cycle arrest but abrogates the senescence-associate

180 egeneration of skeletal muscle, are normally cell cycle arrested but differentiate to generate myocyt

181 ive CDK4/6 inhibitors not only induce tumour cell cycle arrest, but also promote anti-tumour immunity

182 re frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS s

183 iR-200a in metastatic melanoma cells induces cell cycle arrest by targeting CDK6 and decreases the le

184 iral replication and that disruption of this cell cycle arrest can lead to catastrophic DNA damage fo

185 ar to native heart tissue, including mature, cell-cycle-arrested cardiomyocytes.

186 uncovered new details of a specific form of cell cycle arrest caused by this virus, and, importantly

187 to ERS and an attenuation of ERS-associated cell cycle arrest caused by WSPM and multiple prototypic

188 senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of proinfl

189 ly wild-type TP53 exhibited higher levels of cell cycle arrest compared to lines without.

190 ed ATR-dependent phosphorylation of Chk1 and cell-cycle arrest, consistent with replication checkpoin

191 Cell cycle arrest data, comparisons of the inhibition of

192 onclude that CRISPR/Cas9 treatment induces a cell cycle arrest dependent on functional TP53 as well a

193 Downregulation of METTL3 results in cell cycle arrest, differentiation of leukaemic cells an

194 -ranging gene network involved in apoptosis, cell cycle arrest, DNA damage repair, and senescence.

195 colony formation and migration, and induced cell cycle arrest, DNA damage, and apoptosis in CRC cell

196 ed in multiple cellular responses, including cell cycle arrest, DNA repair, apoptosis, metabolism, au

197 ort that SIRT7 is required for p53-dependent cell-cycle arrest during glucose deprivation.

198 roliferation by reducing checkpoint--induced cell-cycle arrest during interphase.

199 and gastrulation movements occurred in these cell cycle-arrested embryos.

200 ch indicated that both compounds promoted G1 cell cycle arrest followed by cellular senescence and ap

201 tes E2F1 transcriptional activity to enhance cell cycle arrest for cell survival.

202 SETD8 ablation rescued the pro-apoptotic and cell-cycle arrest functions of p53 by decreasing p53(K38

203 mitotic proliferation, then enter prolonged cell cycle arrest (G1/G0), during which they transition

204 tor to link inhibition of KRAS signaling and cell cycle arrest (G2/M).

205 l treatment did not affect radiation-induced cell cycle arrest genes or the immediate loss of hematop

206 keletal-microtubule organization, leading to cell cycle arrest, genotoxic stress, and innate immunity

207 duced cell death with caspase activation and cell cycle arrest, however only the GW806742X inhibitor

208 ep in the DNA damage response and subsequent cell cycle arrest; however, the effects of ATM inhibitio

209 d immune cell infiltration without affecting cell cycle arrest in a mouse model of pancreatic cancer,

210 ase inhibitor (HDACi), induced apoptosis and cell cycle arrest in Burkitt and diffuse large B-cell ly

211 enitor (GMP) cells, accompanied by increased cell cycle arrest in CMPs.

212 ssociated secretory phenotype, and reversing cell cycle arrest in epithelial cells from peripheral ai

213 12l could also stimulate cell cycle arrest in G(0)/G(1) phase and induce tumor ce

214 We observed that all compounds inducing cell cycle arrest in G(2)/M phase strongly enhanced the

215 ell death by apoptosis without indication of cell cycle arrest in G0/G1 phase.

216 anner, and silencing SNHG7 expression causes cell cycle arrest in G0/G1.

217 pting a senescence-like state with permanent cell cycle arrest in G1 phase.

218 eplication and repair and is associated with cell cycle arrest in G1.

219 abrogate radiation therapy (RT)-induced G2/M cell cycle arrest in multiple cell lines and, we find th

220 n of IL18RAP inhibited cell proliferation by cell cycle arrest in NKTCL cells.

221 damage response after kidney injury induces cell cycle arrest in renal tubular epithelial cells, res

222 This leads to an S-phase cell cycle arrest in RS4:11 cells corresponding to the d

223 ds to activation of CHK1 or CHK2 kinases and cell cycle arrest in S or G2/M phases.

224 induced significant nuclear localization and cell cycle arrest in S phase, affecting the viability of

225 Cell cycle arrest in SETD1A knockdown senescent cells is

226 also widely accepted that Vif induces G(2)/M cell cycle arrest in several different cell types.

227 ownstream signaling factors and also induced cell cycle arrest in the G(0)/G(1) stage and apoptosis i

228 he miR-34a target genes CDK4/6, and caused a cell cycle arrest in the G(1) phase.

229 tudies indicated that compound 7h can induce cell cycle arrest in the G2/M phase and inhibit prolifer

230 methoxy)-9H-purin-2-amine] leads to G1-phase cell cycle arrest in the marine diatom, Phaeodactylum tr

231 he Sapphire study, we examined biomarkers of cell cycle arrest in the settings of oliguria and/or azo

232 etinoblastoma tumour suppressor, inducing G1 cell cycle arrest in tumour cells.

233 ownregulates cytokine production and induces cell-cycle arrest in MF/SS malignant lymphocytes, inhibi

234 6 inhibitors that induce reversible G1-phase cell-cycle arrest in retinoblastoma-positive tumor model

235 The primary effect of BMP4 on cell fate was cell-cycle arrest, in which RNA sequencing, immunoblot a

236 ated the apoptotic effects, but not the G2/M cell cycle arrest induced by JA.

237 viously demonstrated that prolonged early G1 cell cycle arrest induced by the oral, specific CDK4/6 i

238 Cell cycle arrest inhibits proliferation of the intestin

239 In particular, we found that cell cycle arrest is dependent on the intact enzymatic a

240 Such as cell cycle arrest is initiated upon the pheromone recogn

241 This way, premating cell cycle arrest is linked to the subsequent steps requ

242 Along this process a G2 cell cycle arrest is mandatory.

243 p53-induced cell cycle-arrest is mediated by expression of the CDK i

244 However, PI3K inhibitors primarily induce cell cycle arrest, leaving a significant reservoir of tu

245 y heterogenous phenotypes including extended cell cycle arrest, longer interphase durations, and deat

246 by altering Ca(2+) homeostasis and inhibited cell cycle arrest mediated by the cyclin D1-CDK4 degrada

247 istically, significant enhancement of G(1)-S cell-cycle arrest, mediated by depletion of MYC/MYCN and

248 xA8 siRNA recapitulated exposure to FR, with cell cycle arrest, neuronal transdifferentiation, and co

249 Cell cycle arrest occurred in the G(0)/G(1) phase.

250 acity through IFNgamma and IL4, which led to cell-cycle arrest of tumor cells in a p21-dependent mann

251 cancerous cells, where BRCA2 deletion causes cell cycle arrest or cell death, tumors carrying BRCA2 i

252 tic silencing of S-phase genes and permanent cell cycle arrest or cellular senescence.

253 ally those that induce either only temporary cell cycle arrest or, alternatively, apoptosis in HER2-o

254 Phenotypes are associated with p53-driven cell-cycle arrest or apoptosis, depending on the cell ty

255 aled that CDK4/6 inhibition failed to induce cell-cycle arrest or senescence.

256 bly one of the better studied and involves a cell-cycle arrested or 'stumpy' form that activates meta

257 moted ROS production, enhanced apoptosis and cell cycle arrests particularly.

258 have developed a new approach that utilizes cell cycle arresting patterns as unique molecular signat

259 pression in myoblasts led to cell apoptosis, cell cycle arrest, reduced mitochondrial activities, and

260 C4-2B, 22Rv-1 and PC-3 cells contributed to cell cycle arrest, reduced proliferation, migration and

261 g cellular behaviors (i.e. proliferation vs. cell cycle arrest, respectively).

262 Functional p53 elicits a cell cycle arrest response, whereas, in p53-null transfo

263 We describe that the initial cell cycle arrest resulted from inhibition of the nuclea

264 n of senescent cells characterized by stable cell cycle arrest, resulting in impaired homeostasis, re

265 randed DNA breaks and promoted apoptosis and cell cycle arrest selectively in MSI models.

266 pressive transcription factor FOXO3 promotes cell cycle arrest, senescence and cell death, and mediat

267 diate wild-type cellular responses including cell cycle arrest, senescence, and apoptosis.

268 TDG knockdown in melanoma cell lines causes cell cycle arrest, senescence, and death by mitotic alte

269 fective p53-4KR mice, lacking the ability of cell cycle arrest, senescence, apoptosis, and ferroptosi

270 opment and tumor suppression, independent of cell cycle arrest, senescence, apoptosis, and ferroptosi

271 Although cell-cycle arrest, senescence, and apoptosis are establi

272 tiality of each tRNA family upon response to cell cycle arresting signals.

273 Quiescence (G0) is a transient, cell cycle-arrested state.

274 We show that G(2)/M cell cycle arrest strongly enhances the replication of V

275 brucei RNase H2 (TbRH2A) leads to growth and cell cycle arrest that is concomitant with accumulation

276 y activate DNA repair pathways and avoid the cell cycle arrest that normally accompanies DNA repair.

277 Silencing RABL6A caused PNET cell-cycle arrest that coincided with selective loss of

278 t the RR inhibitor 3-AP actively induces PEL cell cycle arrest through inhibiting the activity of the

279 mage accumulation coupled with inhibition of cell cycle arrest through stimulation of anti-p53- and a

280 th drugs were mediated by induction of G0/G1 cell cycle arrest through upregulation of p27 and downre

281 mportant to ensure the maintenance of the G2 cell cycle arrest to lead the formation of the infective

282 lecular basis of the switch from p53-induced cell-cycle arrest to apoptosis remains poorly understood

283 Cell cycle arrest upon Legionella contact is dependent o

284 ecule-1, calbindin), followed by a marker of cell cycle arrest (urine insulin-like growth factor-bind

285 erences in break sensing are responsible for cell cycle arrest variation.

286 adiation, the tumour suppressor p53 mediates cell cycle arrest via expression of the CDK inhibitor, p

287 necroptosis was linked to increased mitotic cell cycle arrest via Per1/2-controlled Wee1, resulting

288 Cell cycle arrest was reversible at any point by exogeno

289 nd proliferation decreased significantly and cell cycle arrest was seen in both cell lines.

290 Complete cell-cycle arrest was defined as Ki-67 less than or equa

291 heart maturation and postnatal cardiomyocyte cell-cycle arrest, we have performed gene expression pro

292 in (IDP), regulates cell division by causing cell cycle arrest when bound in ternary complex with cyc

293 hat inhibiting PAR-chain turnover results in cell-cycle arrest, which is cytotoxic when combined with

294 delay, DNA double-strand breaks, and G(2)-M cell-cycle arrest, which led to ATR-dependent phosphoryl

295 and slowed proliferation by inducing G(2)-M cell-cycle arrest, while upregulating DNA damage pathway

296 lgae enter cellular quiescence, a reversible cell cycle arrest with drastic changes in metabolism all

297 a breakdown of proteostasis, ISCs coordinate cell cycle arrest with protein aggregate clearance by At

298 solid tumors, ABBV-075 triggers prominent G1 cell-cycle arrest without extensive apoptosis.

299 Notch signaling, yet RSCs remain quiescent (cell cycle-arrested) without damage.

300 tates and later antagonizes TGFbeta-mediated cell cycle arrest, yet remains critical for the patholog