ライフサイエンスコーパス: cell lysis

1 k complex that mediates complement-dependent cell lysis.

2 ss in the ECA-deficient thyA mutants precede cell lysis.

3 smotic change in red blood cells, leading to cell lysis.

4 reased extracellular polymeric substance and cell lysis.

5 from the phagosome, which can result in host cell lysis.

6 signal transduction and induce apoptosis and cell lysis.

7 ytosis, and Ab-dependent complement-mediated cell lysis.

8 ing barrel-like pore structures that lead to cell lysis.

9 ion of the lytic activity to prevent overall cell lysis.

10 nto the peptidoglycan that ultimately led to cell lysis.

11 rocesses were critical for successful target-cell lysis.

12 s spectrometric analysis was performed after cell lysis.

13 ically engineered to induce selective cancer cell lysis.

14 intracellular substrates required for target cell lysis.

15 a beta-barrel transmembrane pore, leading to cell lysis.

16 pression of NK cells and induced MDSC target cell lysis.

17 rane lipids enable intracellular delivery or cell lysis.

18 polymerase chain reaction (RT-PCR) following cell lysis.

19 rocytes that preceded and were not caused by cell lysis.

20 gated proteins is usually thought to require cell lysis.

21 the full-length Lysin A caused M. smegmatis cell lysis.

22 ity is created by rapid ATP depletion during cell lysis.

23 ligands and the subsequent impairment of NK cell lysis.

24 e and impairing CD8(+) T cell-mediated tumor cell lysis.

25 se mixed lineage kinase domain-like to drive cell lysis.

26 ers the lytic cycle of phage propagation and cell lysis.

27 cterial surface to evade complement-mediated cell lysis.

28 TF activity was increased dramatically after cell lysis.

29 s on the cell surface prior to virus-induced cell lysis.

30 ing as an emergency release valve preventing cell lysis.

31 pore in the host cell membrane, resulting in cell lysis.

32 ular P. gingivalis was quantified after host cell lysis.

33 thal effect on the sgrS mutant, resulting in cell lysis.

34 ted with an inhibition of CTL-mediated tumor cell lysis.

35 r level of quantitation, and did not require cell lysis.

36 cells that are particularly refractory to NK cell lysis.

37 surface nanostructure, leading eventually to cell lysis.

38 rolases (PGHs) are responsible for bacterial cell lysis.

39 d induced a mild cell-chaining phenotype and cell lysis.

40 l cell physiology was not perturbed prior to cell lysis.

41 in the osmotic environment, thus preventing cell lysis.

42 lement-dependent antibody-mediated red blood cell lysis.

43 all compartment in the absence of detectable cell lysis.

44 witch and upon filament assembly, leading to cell lysis.

45 of influenza virus, which was accompanied by cell lysis.

46 MD3 lead to a rapid loss of viability and cell lysis.

47 l morphology, inhibiting growth and inducing cell lysis.

48 ns (ATIs) that can protect infectivity after cell lysis.

49 equired for growth with depletion leading to cell lysis.

50 ate (PEP) becomes reduced several days after cell lysis.

51 factors, and in nutrient redistribution, via cell lysis.

52 me, causing membrane damage and, ultimately, cell lysis.

53 5) and helix V) in the G117C mutant prevents cell lysis.

54 r, while DNA barcodes can only be read after cell lysis.

55 disruption of cellular structure, leading to cell lysis.

56 phage repressor (cI(VP882)), leading to host-cell lysis.

57 tions resulting in membrane perturbation and cell lysis.

58 play a major role in NK cell-mediated tumor cell lysis.

59 hich also contributes to adenovirus-mediated cell lysis.

60 trix metalloproteases or complement-mediated cell lysis.

61 T molecules to be more potent in directing B-cell lysis.

62 ophagosome is sufficient for virally induced cell lysis.

63 autophagy plays a role in adenovirus-induced cell lysis.

64 ) into culture medium as a reporter of yeast cell lysis.

65 eath caused by autophagy, cell rounding, and cell lysis.

66 ace, which is directly responsible for tumor cell lysis.

67 nt breaches in wall integrity that can cause cell lysis.

68 les found in the cell envelope, thus causing cell lysis.

69 ls, thereby limiting CD3 bsAb-mediated tumor cell lysis.

70 on lipid reorganization during PFT-mediated cell lysis.

71 he surrounding waters (extracellular) during cell lysis.

72 s results in a transmembrane pore leading to cell lysis.

73 orm functional pores that eventually lead to cell lysis.

74 GTA maturation and eventual release through cell lysis.

75 rmal accumulation of glycerol and subsequent cell lysis.

76 xic T cells to mediate intestinal epithelial cell lysis.

77 lustering and enhanced CD3 bsAb-mediated AML cell lysis.

78 in requires all three components for maximal cell lysis.

79 keleton interactions-and how this relates to cell lysis.

80 SCNPs cause a surge of osmolarity and rapid cell lysis.

81 rovokes a synergistic response that leads to cell lysis.

82 s to prevent CAMP binding, which can lead to cell lysis.

83 rodrug also induced T cell mediated leukemia cell lysis.

84 f the cell's plasma membrane area to prevent cell lysis.

85 enables its conditional inactivation during cell lysis.

86 by serial invasion attempts leading to host cell lysis.

87 formation and IL-1beta cleavage occur before cell lysis.

88 susceptibility, misplaced division septa and cell lysis.

89 ng anemia due to protein instability and red cell lysis.

90 , and mobilizing to new host cells following cell lysis.

91 ate some of this carbon during infection and cell lysis.

92 om the artifact of cytosine deamination upon cell lysis.

93 prevent C3b deposition and, thus, autoimmune cell lysis.

94 -MRSA demonstrated reduced susceptibility to cell lysis (1.78-fold; P = 0.032) and antimicrobial pept

95 hospholipids, leading to membrane damage and cell lysis(1,2).

96 RVA and RVC NSP4s induced BL21-pLysS E. coli cell lysis, a classical viroporin activity assay.

97 s into the growth medium is not due to gross cell lysis, a conclusion that is supported by several li

98 ncrease the efficiency of adenovirus-induced cell lysis, a mechanism that has not been clearly descri

99 in cell permeability, and ultimately caused cell lysis accompanied by the production of membrane tub

100 ESAT-6 (MtbESAT-6) reportedly shows membrane/cell-lysis activity, and recently its biological roles i

101 comedonecrosis, the model predicts: necrotic cell lysis acts as a biomechanical stress relief and is

102 equally cytolytic ( approximately 80% target cell lysis after 4 h), consistent with the similar level

103 induced Hill coefficients of 0.69 for target cell lysis and 0.68 in interferon secretion.

104 e autophagy, which is required for efficient cell lysis and adenoviral spread.

105 tes associated with unstable globins and red cell lysis and also insights into the factors governing

106 tor receptor (EGFR)/Ras pathway, followed by cell lysis and anticancer immunity.

107 nocytes (TIGKs) by measuring cell viability, cell lysis and apoptosis.

108 mycobacteria was developed by optimizing the cell lysis and assay conditions.

109 of phdA in DeltabfmR restored eDNA release, cell lysis and biofilm formation to wild-type levels, wi

110 Further, cell lysis and biofilm formation were governed by the Sr

111 ons for each stage of the method, comprising cell lysis and bisulfite (BS) conversion, preamplificati

112 y and can operate in the absence of complete cell lysis and cell death.

113 lls elicits the effector functions of target cell lysis and cytokine production.

114 Continuous lytic cell lysis and de novo infection allowed LEC culture to

115 I secretion apparatus, eventually leading to cell lysis and death.

116 abfmR mutant biofilms demonstrated increased cell lysis and eDNA release suggesting BfmR to suppress,

117 in (AT), a virulence factor that causes host cell lysis and elicits inflammasome-mediated IL-1beta se

118 okine responses, resulting in enhanced tumor cell lysis and expansion of human tumor antigen-specific

119 de excision repair reaction, are isolated by cell lysis and fractionation, followed by immunoprecipit

120 ls are thought to be perforin (Prf)-mediated cell lysis and gamma interferon (IFN-gamma)-mediated ind

121 te enrichment techniques including red blood cell lysis and immunomagnetic purification.

122 cell suspension is filtered before red blood cell lysis and incubated with the following antibodies:

123 is, a program of cell death characterized by cell lysis and inflammatory cytokine release.

124 biting TGF-beta signaling in T cells reduced cell lysis and leukocyte infiltration in corneas and tri

125 Cell lysis and MAC formation were measured by FACS and i

126 overall workflow consists of methanol-based cell lysis and metabolite extraction with ultrasonicatio

127 d hydrodynamic modeling were used to examine cell lysis and molecular delivery produced by picosecond

128 omplete removal of cell-free RNAs, efficient cell lysis and mRNA capture, achieving highest mRNA dete

129 rrest of root elongation, when root cortical cell lysis and nitrate uptake, as well as cytokinin conc

130 Although cell lysis and outer-membrane vesicle extrusion are poss

131 Cell lysis and proteoform pre-fractionation by gel-elute

132 es that hydrolyze peptidoglycan resulting in cell lysis and release of bacteriophages.

133 h under external mechanical vibration caused cell lysis and released DNA in the supernatant.

134 Following cell lysis and sampling crude cell lysate for analysis,

135 more, histone-induced increases in red blood cell lysis and splenic clearance may be a significant fa

136 hiocyanate, respectively, revealed extensive cell lysis and swelling of cells, consistent with an ins

137 bits EMCV replication and EMCV-mediated beta-cell lysis and that this protection is associated with a

138 through T6SS-mediated killing versus passive cell lysis and the extent of the transfers that occur du

139 Cell lysis and the peak in Stx1 production were substant

140 involved in biofilm formation by controlling cell lysis and the release of genomic DNA, which ultimat

141 a semipermeable membrane, enabling efficient cell lysis and transcript capture.

142 of MIC exposure led to pathogen death due to cell lysis and was enough for pathogen clearance.

143 enomes is prone to artifacts associated with cell lysis and whole-genome amplification.

144 e those that recruit neutrophils, cause host cell lysis, and are involved in the formation of the fib

145 Given that most MC-LR is released only upon cell lysis, and coupled with the moderate strength of th

146 ses to infection, as evidenced by apoptosis, cell lysis, and phagocytosis of infected cells.

147 inantly entered lytic replication, underwent cell lysis, and released new virus.

148 Necroptotic cell lysis, and resultant release of proinflammatory med

149 nctional AmiA or AmiB but not AmiC to induce cell lysis, and that the loss of NlpD phenocopies an Ami

150 es as danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore f

151 A novel cell lysis approach and a larger binding surface through

152 Effective cell lysis approaches that completely release intracellu

153 The mechanisms that contribute to rapid cell lysis are largely unexplored.

154 susceptible to natural killer (NK)-mediated cell lysis as compared with parental cytarabine-sensitiv

155 esulted in lemon-shaped bacteria followed by cell lysis, as previously reported for MreB inhibitors.

156 line K-562 using both live-cell and in-situ cell lysis assay formats, with special focus on metallop

157 trongly inhibited the NK cell-mediated tumor cell lysis associated with inhibition of granzyme B acti

158 tional killing assays measure average target cell lysis at fixed times and high effector:target ratio

159 Faced with hypotonic shock, to circumvent cell lysis, bacteria open large solute-passing channels

160 ficient in IKKbeta were compromised in tumor cell lysis, based on their reduced ability to phagocytiz

161 ing equilibria within cells during and after cell lysis, because sufficient cellular chaperone/chaper

162 Ambient RNA is caused by cell lysis before droplet partitioning and is an importa

163 s were independent of the cell matrix or the cell lysis buffer and were not affected by different ant

164 endations and the use of bead beating, white cell lysis buffer, and an internal control PCR.

165 ch include the appropriate type of red blood cell lysis buffer, FMO or isotype controls to identify r

166 technology and removal of detergent from the cell lysis buffer.

167 lls in this cluster do not undergo cytocidal cell lysis but harbor abundant enveloped particles withi

168 infection of Ostreococcus tauri often causes cell lysis, but two spontaneously arising resistance mec

169 limit viral replication and subsequent beta-cell lysis by attenuating mitochondrial oxidative metabo

170 de of epithelial cell plasticity on targeted cell lysis by cytotoxic T lymphocytes (CTL).

171 Understanding the mechanism of bacterial cell lysis by E will provide insights into new antimicro

172 Simian virus 40 (SV40) appears to initiate cell lysis by expressing the late viral protein VP4 at t

173 ive metabolism attenuates EMCV-mediated beta-cell lysis by inhibiting viral replication.

174 ane protein E whose expression leads to host cell lysis by inhibition of the peptidoglycan synthesis

175 Our methodology of studying E. coli cell lysis by Lysin A and its truncations after expressi

176 ing to optimal TRAIL expression and melanoma cell lysis by pDCs.

177 Triggering cell lysis by peptidoglycan synthesis inhibition is a tr

178 tive effect resulted from inhibition of host cell lysis by pneumococcal cholesterol-dependent cytotox

179 determination of the efficiency of recipient cell lysis catalyzed by this intercellular toxin deliver

180 man endothelial cells and, in the absence of cell lysis, cause two diseases resulting from increased

181 release valve, preventing the occurrence of cell lysis caused by acute osmotic stress.

182 laser-based cellular manipulation including cell lysis, cell necrosis, and molecular delivery.

183 functions (i.e., single cell sampling probe, cell lysis container, microreactor, and nano-ESI emitter

184 y suggest that DNA release by phage-mediated cell lysis contributes to C. difficile biofilm formation

185 ong correlation between results from on-chip cell lysis, conventional off-line lysis and ELISA confir

186 ession was lacking and no spontaneous target cell lysis could be detected in vitro, although perforin

187 Cell lysis destabilizes the apparent 60-kDa tetramer, le

188 r thick, chitin-reinforced cell walls render cell lysis difficult, complicating their analysis and id

189 Cell lysis, DNA extraction, and hydrolysis were accompli

190 Five others cause frequent cell lysis during cell separation and map to two loci.

191 and rga7Delta result in defective septum and cell lysis during cytokinesis.

192 ease assays, this mutant exhibited increased cell lysis during stationary phase, suggesting that olig

193 d selective cell clearance was achieved with cell lysis efficiencies of 94 and 96%.

194 ession of granzyme B-dependent CD107a and MM cell lysis, even in the presence of bone marrow stromal

195 The entire protocol including cell lysis, extraction of DNA, polymerase chain reaction

196 in bacteriophage genomes, where they promote cell lysis for virion release, and within bacterial geno

197 ogical emergency release valve that prevents cell lysis from acute osmotic stress.

198 andard biochemistry laboratory equipment for cell lysis, gel electrophoresis and western blotting.

199 We used HSV1716/NAT as a dual cell lysis-gene delivery vehicle for targeting the NAT t

200 Cell lysis genes that are induced following PrtR autocle

201 ough the exact sequence of events leading to cell lysis has not yet been completely elucidated.

202 Different mechanisms for cell lysis have been proposed, but these models tend to

203 Specifically, we used cryogenic cell lysis, immunopurifications on magnetic beads, and m

204 Even when considering the fastest phage (cell lysis in 9 minutes), the concentrations of phage-in

205 ation of removable electrodes for electrical cell lysis in a specified portion of the channel (1 mm w

206 However, cell lysis in microwells remains challenging despite the

207 iated by plasma membrane pores, similarly to cell lysis in pyroptosis and necroptosis(3,4).

208 d donor-type (B/c) but not third-party (C3H) cell lysis in sensitized BKO hosts.

209 equires demonstration that a small amount of cell lysis in the cellular population is not responsible

210 ecific antibody efficiently induces targeted cell lysis in the presence of effector cells at as low a

211 Ab-dependent complement activation and tumor cell lysis in vitro.

212 suggested DSW stimulation of phage-mediated cell lysis, in previously infected cells.

213 Production of FFA has been shown to cause cell lysis, induce stress responses, and impair basic ph

214 pase activation as part of the mechanism for cell lysis induced by adenovirus and suggests that manip

215 metal ions into the cells and accelerate the cell lysis induced by Rituximab.

216 a a multistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitiz

217 lular signaling molecule able to amplify the cell lysis inflicted by certain bacterial toxins includi

218 lease of DnaK via secretion and/or bacterial cell lysis into the extracellular milieu and inhibition

219 the enlargement of wall defects, after which cell lysis is consistent with both the inner and outer m

220 ion of infectious material in the absence of cell lysis is enabled by components of the autophagy pat

221 We show DNA released via cell lysis is readily available for HGT and may be parti

222 IS (icIS), which is unable to trigger target cell lysis, is loose, with multiple protrusions in the e

223 Here, we show that cell lysis may be enabled by a process of toxins targeti

224 In this study, we describe a novel cell lysis mechanism for fungal and tumor cells by the p

225 odes of action for these antibiotics include cell lysis, membrane depolarization, inhibition of cell

226 n bubble dynamics that lead to laser-induced cell lysis, necrosis, and molecular delivery.

227 Thus, our data show that, prior to cell lysis, non-enveloped viruses are secreted within in

228 of cell wall synthesis and cell division and cell lysis occurred for the higher antibiotic dose.

229 ing conidial-base germ tube degeneration and cell lysis occurring during growth, a phenomenon exacerb

230 In this monolithically integrated device, cell lysis occurs at a channel intersection using a comb

231 Phage-mediated cell lysis of dual-membrane Gram-negative bacteria also

232 first evidence that the susceptibility to NK cell lysis of EBV-infected B cells undergoing lytic repl

233 s composed of C5b to C9 (C5b-9) and mediates cell lysis of invaded pathogens.

234 Viral infection led to mass cell lysis of the O. tauri cells within 48 h.

235 Endolysin CD27L causes cell lysis of the pathogen Clostridium difficile, a majo

236 Overexpression of bsrE causes cell lysis on agar plates.

237 r targets without the interfering effects of cell lysis on vacuole polyP and of endopolyphosphatases.

238 cribed mechanism is independent of explosive cell lysis or cell death, and the release of DNA is conf

239 VRE biofilms while showing minimal red blood cell lysis or cytotoxicity against HeLa cells.

240 neral phenomenon and is not a consequence of cell lysis or membrane shedding; instead, their secretio

241 nic carbon analyses suggest that products of cell lysis or microbial products released under starvati

242 s impulse J greater, similar0.1 Pa s ensures cell lysis or necrosis, whereas exposures in the range o

243 This protocol, which includes cell lysis, overnight tryptic digestion, sample analysis

244 We suggest that activation of the Alp cell lysis pathway is a disease-enhancing response to ba

245 at impaired respiration elicits a programmed cell lysis (PCL) phenomenon in S. aureus leading to the

246 The cell lysis potential of different IL/buffer combinations

247 Moreover, cell lysis procedures can be hard to standardize, leadin

248 Cleavage of AlpR triggers a cell lysis program through de-repression of the alpA gen

249 thelial cell death via pyroptosis results in cell lysis, proinflammatory cytokine release and escape

250 bound to viral RNA are cross-linked prior to cell lysis, purified, and identified using mass spectrom

251 Mechanisms such as exudation and cell lysis release these phytoplankton-derived sulfur me

252 her with meropenem resulted in rapid, polar, cell lysis releasing cytoplasmic contents.

253 ammation in a manner independent of MLKL and cell lysis remains unclear.

254 uring cellular manganese (Mn) levels require cell lysis, restricting longitudinal experiments and mul

255 ough A2B5+, O4+, and O1+ complement-mediated cell lysis resulted in a delay in development of MBP cel

256 However, cell lysis revealed a viscoplastic response of the under

257 ster cells by micromanipulation, followed by cell lysis, reverse transcription, gene-specific cDNA am

258 zed to activate and induce tumor-directed NK cell lysis since IL-2-stimulated NK cells mediated tumor

259 Cell lysis solvent and PB reagent (acetone or benzopheno

260 nvelope and specifically eliminates, through cell lysis, sporulating cells that assemble the envelope

261 hesize that small molecules added during the cell lysis stage can yield soluble protein from insolubl

262 y plaque assay, whereas phageFISH identified cell lysis starting at < 5 h and lasting to 11 h, but fo

263 nt process induced by apoptosis, necrosis or cell lysis substances, respectively.

264 phaS in intact normal neurons, but not after cell lysis, suggesting a dynamic equilibrium.

265 ery continues moving circumferentially until cell lysis, suggesting that cross-link cleavage is not r

266 pGpp, limiting fatty acid synthesis leads to cell lysis, supporting a role for ppGpp as a linchpin li

267 d and postulated functions and uses of these cell lysis systems.

268 ion analysis of few single cells, a one-step cell lysis, target labelling and hybridisation approach

269 Unlike eDNAs from cell lysis that were abundant and mainly concentrated ar

270 lobin is diluted into blood plasma after red cell lysis, the disassembly pathway appears to be domina

271 Upon cell lysis, the modified drug bound to the protein is pu

272 accumulate large amounts of polyP, and upon cell lysis, the release of the vacuolar polyP could nonp

273 Starting from cell lysis, this protocol can be completed in approximat

274 n recent experimental observations of single-cell lysis times in bacteriophage [Formula: see text] He

275 and experimentally assessed metabolites from cell lysis to better understand viral roles in this ecos

276 ctivity buffer expedites the transition from cell lysis to protein electrophoresis.

277 ral selection, and yet many bacteria undergo cell lysis to release anti-competitor toxins [1-5].

278 d other metabolites, likely released through cell lysis, to supplement metabolic pathways.

279 ve therapeutic combination of tumor-specific cell lysis together with immune stimulation, therefore a

280 is localized to the pole and does not cause cell lysis under physiological conditions.

281 action of viruses, once they are released by cell lysis, undergo fast decomposition.

282 chains for phospholipid synthesis results in cell lysis unless RpfB is present to counteract the RpfF

283 ese channels act as safety valves preventing cell lysis upon hypoosmotic cell swelling: the channels

284 y active domains, both of which show E. coli cell lysis upon their expression exclusively in the peri

285 s the challenge of sample homogenization and cell lysis using magnetic rotation of an external magnet

286 ring of the complement cascade induces tumor cell lysis via complement-dependent cytotoxicity (CDC) a

287 Impaired respiration led to increased cell lysis via divergent regulation of two processes: in

288 evealed that Fn14 dimerization occurs during cell lysis via formation of an intermolecular disulfide

289 tides that were capable of inhibiting target cell lysis via interaction with CD94-NKG2A, yet had litt

290 To investigate the contribution of VP4 to cell lysis, VP4 was expressed in mammalian cells where i

291 n), target cell conjugation, and K562 target cell lysis was compared between mutant- and wild-type-tr

292 d to prevention of macrophage activation and cell lysis, we suggest that the molecular environment su

293 Swab extraction and cell lysis were accomplished using magnetic-driven agita

294 a secretion, proliferation, and CD8-specific cell lysis) were markedly repressed.

295 efects and formed membrane blebs that led to cell lysis when GlcNAc was replaced by chitobiose in the

296 ation and was associated with an increase in cell lysis, which was suppressed by a calcium-dependent

297 cles are released primarily by virus-induced cell lysis, while in insect cells they bud from the plas

298 high-quality RNA requires the use of direct cell lysis with a phenol guanidine-based reagent or an a

299 es have a single lysis protein that achieves cell lysis without enzymatically degrading the PG.

300 Because cell lysis would be detrimental to epithelial nitric oxi