ライフサイエンスコーパス: cell membrane

1 without having to access either sides of the cell membrane.

2 otetrahexosylganglioside, a component of the cell membrane.

3 solutions, comparable to lipid bilayers of a cell membrane.

4 port of biologically active cargo across the cell membrane.

5 ts the Par complex to polarized sites on the cell membrane.

6 quantitation of O-glycans derived from human cell membrane.

7 onditions likely by permeabilizing the yeast cell membrane.

8 optimal interaction state when binding to a cell membrane.

9 e movement of Na(+) and K(+) ions across the cell membrane.

10 genomic DNA, and (iii) the disruption of the cell membrane.

11 acterized by the leak of bulk water from the cell membrane.

12 nd Cd nanoparticles (NPs) were adsorbed onto cell membrane.

13 ransmit an extracellular stimulus across the cell membrane.

14 ngiotensin converting enzyme 2 (ACE2) on the cell membrane.

15 ector-binding interfaces are occluded by the cell membrane.

16 xotoxins that create lytic pores in the host cell membrane.

17 any bacteria to move substrates across their cell membrane.

18 ansmitting intracellular actomyosin force to cell membrane.

19 tive pheromone lipoproteins localized at the cell membrane.

20 glycoproteins to bind and fuse with a target cell membrane.

21 ch facilitates thiamine transport across the cell membrane.

22 7 and 18 aggregated and failed to target the cell membrane.

23 y physically disrupting the integrity of the cell membrane.

24 ose on the cytoplasmic side of the bacterial cell membrane.

25 with surface protein in Campylobacter jejuni cell membrane.

26 for the cannabinoid-GlyR interaction in the cell membrane.

27 T can act as a bivalent ligand of KLA in the cell membrane.

28 ht-induced protons/ions transport across the cell membrane.

29 nvestigate nanoscale mechanics of the living cell membrane.

30 el cyclotides interact with and permeabilize cell membranes.

31 r that result in the fusion of the viral and cell membranes.

32 n" model of steroid hormone transport across cell membranes.

33 R2/ERBB2) in vesicles derived from mammalian cell membranes.

34 e generation and maintenance of asymmetry in cell membranes.

35 lichia membranes were not trafficked to host-cell membranes.

36 he movement of a number of substrates across cell membranes.

37 location of the GLUT4 glucose transporter to cell membranes.

38 iotinylated saporin, a toxin unable to cross cell membranes.

39 heterogeneities of different origins in live-cell membranes.

40 sodium, potassium, and chloride ions across cell membranes.

41 ibution of efflux and influx carriers on the cell membranes.

42 Js facilitate small molecule transfer across cell membranes.

43 resence of intracellular virus and disrupted cell membranes.

44 polyphosphoinositides, is distributed within cell membranes.

45 ceptors CD4 and CCR5 and fuses the viral and cell membranes.

46 to maintain the lipid saturation balance of cell membranes.

47 rties, attacking bacteria and destroying the cell membranes.

48 otic aminophospholipids (aPL) in circulating cell membranes.

49 omotes sequestration of KATP from myocardial cell membranes.

50 ltiprotein nanomachines that puncture target cell membranes.

51 through organizing an interaction network on cell membranes.

52 xceed the low-pass corner frequency of their cell membranes.

53 tor binding and fusion of the viral and host cell membranes.

54 orms transmembrane beta-barrel pores in host cell membranes.

55 oth, decreases integrin levels on the border cell membranes.

56 aciously because it has the ability to cross cell membranes.

57 decidual cell cytoplasm and cytotrophoblast cell membranes.

58 plants by promoting Ca(2+) efflux across the cell membranes.

59 holipids as the primary constituent of their cell membranes.

60 ated in effector translocation across target cell membranes.

61 rticularly in the brain, cardiac, and immune cell membranes.

62 are the primary nanomechanical responses of cell membranes.

63 ovement of another lipid-cholesterol-between cell membranes.

64 mental mechanism for protein distribution in cell membranes.

65 average protein and glycan heights on native cell membranes.

66 a similar capacity for fusion with the host-cell membrane(5).

67 se to excite single microbubbles tethered to cell membranes, a transient pore on the cell membrane (s

68 hways in Enterococcus faecalis that regulate cell membrane adaptation in response to antibiotics.

69 Targeting LOV2GIVe to cell membranes allowed for light-dependent activation of

70 , which in turn increases the tension of the cell membrane, alters tissue mechanics, and drives a mor

71 ely identify protein-protein interactions on cell membranes, an approach we term MicroMap (muMap).

72 phatidylserine, an integral component of the cell membrane and 'eat-me' signal recognized by macropha

73 by glucose metabolism, depolarization of the cell membrane and an influx of calcium, which initiates

74 tonin 5A receptors, which translocate to the cell membrane and become active upon chronic, but not ac

75 hort-A-bands lying close to the outer muscle cell membrane and between normally spaced A-bands.

76 leading to the assembly of nanopores at the cell membrane and causing cell death.

77 mbrane of proteins that are activated at the cell membrane and diffuse throughout the cytosol.

78 duced localization of the transporter to the cell membrane and diminished secretion of apoE.

79 te that Nef recruits both Itk and Btk to the cell membrane and induces constitutive kinase activation

80 MC N-terminal domain that forms pores on the cell membrane and induces pyroptosis.

81 ulating cells and factors to the endothelial cell membrane and its receptors.

82 elongated wave segment that is enclosed by a cell membrane and moves in a highly persistent fashion.

83 suggests that COVID-19 may modulate the red cell membrane and present novel antigenic epitopes.

84 ouse hepatoma cells as it easily crosses the cell membrane and qualitatively traces the localization

85 on and clustering of alpha4 integrins on the cell membrane and subsequent activation of the FAK-RhoA

86 (ASAP1) establishes a connection between the cell membrane and the cortical actin cytoskeleton.

87 t to promote the loss of beta-catenin at the cell membrane and total E-cadherin loss.

88 As a consequence of assumed isotropy, the cell membrane and underlying cytoskeleton are expected t

89 EGFL9 and cMET co-localize at both the cell membrane and within the mitochondria.

90 terol is an integral component of eukaryotic cell membranes and a key molecule in controlling membran

91 These Heinz bodies become deposited on the cell membranes and can lead to hemolysis.

92 spatial resolution necessary for visualizing cell membranes and eukaryotic subcellular organelles.

93 iruses also encode proteins that localize in cell membranes and negatively regulate superinfection an

94 n shown to alter the lateral organization of cell membranes and reconstituted phospholipid bilayers;

95 omers, dimers, and higher-order oligomers in cell membranes and show that oligomeric structure become

96 the translocation of nascent proteins across cell membranes and the integration of proteins into the

97 ion of cationic nanoparticles with bacterial cell membranes and the subsequent biological impact.

98 event initiates the fusion of viral and host cell membranes and then the viral entry into the host ce

99 he steady-state distribution of PFAAs across cell membranes and thus toxicity.

100 cted into HEK293 cells, it inserted into the cell membrane, and initiated cellular signaling.

101 cleotides in genetic molecules, phospholipid cell membranes, and energy transfer molecules such as ad

102 rved in liposomes, low-density lipoproteins, cell membranes, and plasma.

103 tively charged oleic acid (OA), a well-known cell membrane antioxidant, prevents the oxidation of the

104 nd interpret nanomechanical responses of the cell membrane are demonstrated.

105 Proteins on cell membrane are modified by N- and O-glycans.

106 posed on the lipid bilayer components of the cell membrane are the main parameters responsible for th

107 r the trafficking of carboxylate ions across cell membranes are becoming clearer.

108 a large number of viable cells with impaired cell membranes are observed, shown by both selective pla

109 ation of potentially toxic Cu(+) ions across cell membranes are unknown.

110 s that RBC shape responses occur at constant cell membrane area but with membrane shear moduli that v

111 the flagellar pocket, an invagination of the cell membrane around the proximal end of the flagellum,

112 "on-off" switch in cECs to hyperpolarize the cell membrane as extracellular K(+) increases.

113 Mutant p53-enforced GAP isoforms lose cell membrane association, leading to heightened KRAS ac

114 hosphoinositides and liposomes and for plant cell membrane association.

115 fungal cell wall binding, penetration of the cell membrane at discrete foci, followed by gradual loss

116 hannels like KcsA enable ions to move across cell membranes at near diffusion-limited rates and with

117 Glycans decorate proteins and cell membranes at the cell-environment interface, and mo

118 not be justified, such as the evolution of a cell membrane before the evolution of enzymatic cooperat

119 at the designed alkyl CPs strongly penetrate cell membranes, binding to KRAS and NRAS mRNAs under low

120 outer leaflet is important for understanding cell membrane biology in health and disease.

121 A cell membrane biosensor was constructed by using the cel

122 ind that the thrombin receptor PAR4 triggers cell membrane blebbing in a RhoA-and beta-arrestin-depen

123 BNP were found to be the natural ligands for cell membrane-bound guanylyl cyclase receptors that medi

124 Past studies predict that the cell membrane buds at low resting tensions and stalls at

125 Both peptides disrupted bacterial cell membranes, but only the active peptide displayed th

126 ing small molecules (RNA, DNA, drugs) across cell membranes by application of an electrical field.

127 onstrate that antimicrobials that depolarize cell membranes can benefit cells when the terminal elect

128 Human GDE3 expressed in HEK293T cell membranes catalyzed the conversion of lysophosphati

129 in a failure to transmit actomyosin force to cell membrane, causing an expansion of apical surfaces.

130 that fluorescence was located mainly at the cell membrane (CHO-hM(2)R cells).

131 Coating Au@Rh nanostructures with tumor cell membrane (CM) enables tumor targeting via homologou

132 OX-loaded MONs coated with 4T1 breast cancer cell membranes (CM@MON@DOX) show greater accumulation at

133 ral evolutionary strategies to protect their cell membranes (CMs) from the attack of antibiotics and

134 , it is reported that genetically engineered cell-membrane-coated magnetic nanoparticles (gCM-MNs) ca

135 Here, cancer-cell-membrane-coated mesoporous organosilica nanoparticl

136 The nanoparticles are fabricated using a cell membrane coating derived from cancer cells engineer

137 The combination of cell-membrane-coating nanotechnology and genetic editing

138 l as the synthesis of protein, cell wall and cell membrane components required for cell enlargement.

139 of silica for establishing interactions with cell membrane components to initiate toxicity.

140 terol is an essential component of mammalian cell membranes, constituting up to 50% of plasma membran

141 ing MTs/dynein and actomyosin, ensuring that cell membrane contractility is tightly controlled to exe

142 ich a sudden decrease in cell population and cell membrane damage have been observed.

143 n the WT and mutant strains, LA induced more cell membrane damage in the T7SS mutants compared to the

144 yo-electron tomography, TIRF microscopy, and cell membrane-derived vesicles called blebs, Ward et al.

145 of this study was to determine if transient cell membrane disruptions (TPMDs) in single keratocytes

146 increases sequestration of these proteins in cell membranes, disrupts regulation of CRC promoting gen

147 s required for tethering cortical F-actin to cell membrane domains outside the adherens junctions (AJ

148 Synaptic puncta move all over the hair cell membrane during recovery, translocating far from th

149 ), induce fusion of the virion envelope with cell membranes during entry, and between cells to form p

150 retical effort, the underlying mechanisms of cell membrane electroporation are not sufficiently eluci

151 6) and a label-free quantitative proteome of cell membrane-enriched components was performed.

152 Ls), one of the main components of bacterial cell membranes, exhibit high levels of structural comple

153 dissociation of cavin-1 from caveolae allows cell membrane expansion that occurs upon insulin-aided l

154 sma membrane vesicles (or blebs) from native cell membranes expressing appropriate receptors as targe

155 nergic mechanisms that include modulation of cell membrane fluidity, regulation of intracellular sign

156 Dengue virus (DENV) subdues cell membranes for its cellular cycle by reconfiguring p

157 ycans and glycolipids isolated from the same cell membrane fractions were analyzed in parallel using

158 HIV-1 Tat protein can penetrate cell membrane freely and secrete into extracellular medi

159 y detailed view of Serinc restriction of HIV-cell membrane fusion and thus extend current structural

160 rd et al. visualize intermediates of the HIV-cell membrane fusion process and demonstrate how Serinc

161 escape strategies and review the strategy of cell membrane fusion, a recent strategy for direct deliv

162 onformation during the early events of virus-cell membrane fusion.

163 cellular invasion and resistance in driving cell membrane fusion.

164 o included Zn(2+), a significant increase in cell membrane GLUT1 was measured, thus providing a cellu

165 ycans were chemically released from isolated cell membrane glycoproteins following N-glycan and lipid

166 The ability of lytic peptides to engage with cell membranes has been exploited for drug delivery to c

167 owders, and transient DNA attachments to the cell membrane have all been implicated in the organizati

168 , the nanomechanical responses of the living cell membrane have been elusive due to complexities in t

169 measurements of molecular heights on native cell membranes have been difficult to obtain.

170 phan to enhance hydrophobic interaction with cell membranes, histidine to facilitate endosomal escape

171 echniques have focused on damaging adipocyte cell membranes, hydrolyzing triglycerides (TGs), or indu

172 , associated with actomyosin dysfunction and cell membrane hyper-contractility.

173 midgut tissue revealed genes associated with cell membrane, immune response, detoxification, and pote

174 fficking of TRPA1 channels in and out of the cell membrane in brainstem astrocytes contributes to the

175 y increasing the FZD4 co-receptor TSPAN12 at cell membranes in an MAPK/ERK kinase (MEK)/ERK-dependent

176 DNA-lipid-P and is thus able to insert into cell membranes in situ.

177 may be attributed to its role in maintaining cell membrane integrity and permeability.

178 the probe, as reducing ends were exposed and cell membrane integrity was compromised.

179 xidative stress response, and maintenance of cell membrane integrity, further confirm this phenomenon

180 hat exposure to these cyclotides compromises cell membrane integrity.

181 le delivering lipids to the cell to maintain cell membrane integrity.

182 Cell-membrane integrity decreased under dark conditions

183 s or pests, these proteins modify and damage cells' membranes, interact with immune receptors, and mo

184 procedure to characterize the nanostructure-cell membrane interface using focused ion beam and scann

185 This involves early adhesion to ARPE cell membrane, internalization and localization of Pg wi

186 ilization of these proteins solubilized from cell membranes into detergents is a challenging task.

187 e effect of possible pore overlapping on the cell membrane, introducing a dimensionless quantity that

188 Upon application of an electric field, the cell membrane is compromised, allowing the delivery of e

189 if the electroporation behavior of a reduced cell membrane is consistent with time-resolved, atomisti

190 ts suggest that cholesterol diffusion in the cell membrane is heterogeneous and that this diffusional

191 h as endocytosis and caveolae formation, the cell membrane is locally deformed into curved morphologi

192 mechanisms of nanoparticle interaction with cell membranes is essential for designing materials for

193 Cholesterol, a necessary component of animal cell membranes, is also needed by the lethal human malar

194 F60V) ) causes a delay in TNFR1 transport to cell membrane, leading to sustained receptor responsiven

195 lica surface that initiate interactions with cell membranes, leading to pathological outcomes.

196 production is related to tannic acid causing cell membrane leakage allowing fluoride ions easy access

197 mputer modelling studies of transport at the cell-membrane level, and considers alternative diffusion

198 We studied pHLIP ICG interaction with the cell membrane lipid bilayer, the pharmacology and toxico

199 past temperature variability using bacterial cell membrane lipids (branched glycerol dialkyl glycerol

200 P5L delayed cell membrane localisation but once recruited into the m

201 G389R delayed cell membrane localisation, trended to decrease extracel

202 In multiple cancer cells, cell membrane-located GRP78 has been reported to act as

203 Cell membranes mainly consist of lipid bilayers with an

204 f bioactive molecules, including drugs, into cell membranes may produce indiscriminate changes in mem

205 r signaling proteins and transporters at the cell membrane; MLXIP that, with the previously identifie

206 Here, we report that hybrid cell membrane nanovesicles (known as hNVs) displaying SI

207 Using this method, we identified 44 cell membrane O-glycan isomers with MS/MS, and, among th

208 , which are held in an optical trap near the cell membrane of a macrophage.

209 ovel therapy that can potentially target the cell membrane of C. difficile to minimize relapse in the

210 The envelope protein was expressed on the cell membrane of the stem cells and was critical in main

211 ed with thiol functional groups in bacterial cell membranes of two extensively studied Hg(II) methyla

212 e by exporting different therapeutics across cell membranes, often by utilizing the H(+) electrochemi

213 ucleases (DNases) which cells may express on cell membrane or secret to the culture environment.

214 Practitioners must segment cell membranes or cell nuclei from a tissue and annotate

215 on oxidation are not necessarily confined to cell membranes or exclusively related to respiration.

216 ross a single barrier (i.e. the vasculature, cell membrane, or endosomal compartment), but fail to de

217 g been considered to be a central element of cell membrane organization.

218 nsight into the organizational principles of cell membranes over the past decades.

219 demonstrate greater than threefold enhanced cell membrane penetration in breast, cervical, and multi

220 including 7e, 7f, 7g, and 9k, that addressed cell membrane permeability and other physicochemical iss

221 rthermore, the compounds exhibited excellent cell membrane permeability in living cells and a higher

222 d with microbubbles can efficiently increase cell membrane permeability resulting in enhanced tissue

223 ed targeting mechanism is introduced, termed cell membrane permeability targeting (CMPT), which impro

224 used in medicine to transiently increase the cell membrane permeability via electroporation to delive

225 els of riboflavin (2.4-3.6 muM) and improved cell membrane permeability, with a positive correlation

226 into this added mechanism of action, induced cell membrane permeabilization, can be inferred from stu

227 A cell membrane-permeable form of 2',3'-cAMP and 3'-AMP mi

228 able, as directly targeting complex II using cell membrane-permeable metabolites also controlled infe

229 as attributed to a lethal increase in cancer cell membrane polarity due to ABCA1 inhibition and subse

230 re, to address these limitations, we use the cell membrane potential as a bioenergetic indicator of E

231 We prove that light driven perturbations of cell membrane potential induce homeostatic reactions and

232 entifies subpopulations of neutrophils where cell-membrane potential functions as a rheostat to modul

233 roscopy revealed that SHCA clustering at the cell membrane preceded LPP recruitment.

234 Cluster of differentiation 20 (CD20) is a B cell membrane protein that is targeted by monoclonal ant

235 We discovered that T cell membrane proteins are transferred specifically to t

236 1,2-mannosylated N-glycans present on cancer cell membrane proteins may serve as therapeutic targets

237 oeba histolytica acquires and displays human cell membrane proteins, enabling immune evasion.

238 tors (GPCRs) represent the largest family of cell membrane proteins, with >800 GPCRs in humans alone,

239 heterodimers, and cholesterol binding in the cell membrane rafts.

240 e, involving classic signaling (IL-6->IL-6R) cell membrane receptors, transsignaling (IL-6->soluble I

241 integrated approach to achieve light-induced cell membrane recruitment and homo-interaction of intrac

242 To better understand the link between cell membrane regulation and chemical composition, we es

243 MG53 (TRIM72) is essential for cell membrane repair and is believed to be a muscle-spec

244 We demonstrate that cell membrane repair pathways play the main role in this

245 psulating CRISPR/Cas9 (CC-ZIF) with a cancer cell membrane resulted in the uniformly covered C(3)-ZIF

246 nd modulates the efflux of many drugs at the cell membrane, resulting in inadequate retention of chem

247 TCC formation on cell membranes results in a transmembrane pore leading t

248 es and promote healing, pathways ending with cell membrane rupture may incite deleterious proinflamma

249 ion (a proton), which then pass through the cell membrane separately and recombine inside.

250 ear motion constrained inside the enveloping cell membrane show that concentration-dependent stochast

251 ange of gene expression changes tapping into cell membrane signaling, intracellular signaling, and tr

252 d to cell membranes, a transient pore on the cell membrane (sonoporation) is generated which allows i

253 Cell membrane staining and toxin neutralization studies

254 ngus, but the fungus became less tolerant to cell membrane stress.

255 sion and preservation of genome information, cell membrane structure and function, and metabolism.

256 complexes, which are transported through the cell membrane subsequently interacting with gp130 to cos

257 o a small region of cone outer segments: the cell membranes surrounding the axonemes.

258 y physico-mechanical forces on the bacterial cell membrane that will ultimately result in cell death.

259 the EMI model, the extracellular space, the cell membrane, the intracellular space and the cell conn

260 gering its down-regulation from the producer cell membrane through an AP-2-dependent endolysosomal pa

261 we report that Ambn binds to ameloblast-like cell membranes through a highly evolutionary conserved a

262 Ambn variants, we showed that Ambn binds to cell membranes through a motif within the sequence encod

263 bility is the temporary creation of pores in cell membranes through a phenomenon called sonoporation

264 y synthesized peptidoglycan polymer from the cell membrane to complete integration into the cell wall

265 nduces undulations in the underlying elastic cell membrane to form patterns on the cell surface.

266 ific information is transmitted across the T-cell membrane to initiate intracellular signaling.

267 n among these is the permeabilization of the cell membrane to large molecules.

268 challenging due to the impermeability of the cell membrane to proteins.

269 The trafficking of host-cell membranes to Ehrlichia inclusions was dependent on

270 in catalyzes fusion between viral and target cell membranes to initiate infection.

271 eptible cell and induces fusion of viral and cell membranes to initiate infection.

272 processes that range from transport through cell membranes to neurotransmission.

273 rs(1-4), followed by fusion of the virus and cell membranes to release the virus genome into the cell

274 simulated the interaction of OMVs with host cell membranes to understand why OMV uptake depends on t

275 effectors into host cells that subvert host cell membrane trafficking, leading to the biogenesis of

276 ycoprotein (P-gp), also known as ABCB1, is a cell membrane transporter that mediates the efflux of ch

277 Here, we investigated if cell membrane transporters are involved in the cellular

278 Cell membrane transporters facilitate the passage of nuc

279 and egg culminates with the fusion of their cell membranes, triggering the molecular events that res

280 resulted in the uniformly covered C(3)-ZIF((cell membrane type)).

281 ggered by accumulation of oxidized lipids in cell membranes unless the lipid hydroperoxidase, glutath

282 nd interfere with protein trafficking to the cell membrane upon infection.

283 ract full-length chicken ASIC1 (cASIC1) from cell membranes using styrene maleic acid (SMA) copolymer

284 microswitches to transmit signals across the cell membrane via an allosteric network encompassing the

285 ion (ROMP) that can insert directly into the cell membrane via the incorporation of long alkyl chains

286 emergence of Fe-containing particles on the cell membrane, we provide evidence of a diminished role

287 s to Ehrlichia In addition, DiI-labeled host-cell membranes were trafficked to autophagosomes induced

288 dioctadecylindocarbocyanine)-prelabeled host-cell membranes were unidirectionally trafficked to Ehrli

289 lectrostatically binds anionic lipids at the cell membrane, where it encounters SecA2.

290 Wild-type PgCad1 was transported to the cell membrane, whereas PgCad1 produced by r14 was not.

291 spherical shape when they interact with host cell membranes, whereas OMVs with shorter (rough-type) l

292 r type of circuits composed of channels in a cell membrane, which regulate and amplify transport of i

293 Alanine ethyl ester readily crosses cell membrane while simultaneously assessing extracellul

294 Bacteria surround their cell membrane with a net-like peptidoglycan layer, calle

295 We found that KRAS4B colocalizes on the cell membrane with other RAS isoforms and a subset of pr

296 ymeric cores wrapped with modified red blood cell membrane with two inserted key components: melittin

297 ed on pore formation and permeabilization of cell membranes with acoustic waves.

298 ral sugars provides a powerful tool to label cell membranes with chemical tags for subsequent targete

299 fficking, we observed dynamic changes in the cell membrane, with spherical membrane protrusions that

300 nsor fluorophore so that it can pass through cell membranes without staining intracellular compartmen