ライフサイエンスコーパス: cell motility

1 nd highlight the heterogeneity of GC for Tfh cell motility.

2 regulator of cancer bioenergetics and tumor cell motility.

3 EST, and was critical for CtBP2 induction of cell motility.

4 cells exhibited lower tension and decreased cell motility.

5 g edge that controls membrane protrusion and cell motility.

6 nhibition of LINC00313-induced repression of cell motility.

7 rotrusive and contractile forces for optimal cell motility.

8 and rupture, ultimately resulting in reduced cell motility.

9 , track cell morphology changes, and monitor cell motility.

10 filin1 (Pfn1) in VASP-mediated regulation of cell motility.

11 essential roles in neuronal development and cell motility.

12 across mammals and birds and a regulator of cell motility.

13 so regulates PI3K/Akt signaling and infected cell motility.

14 protein is necessary for TGF-beta1-dependent cell motility.

15 changes in epithelial cell-cell adhesion and cell motility.

16 ng edge of cells and play important roles in cell motility.

17 423) signaling pathway, thus increased tumor cell motility.

18 mellipodia are common features of eukaryotic cell motility.

19 or properly localizing adhesion sites during cell motility.

20 uction and cytoskeletal pathways that govern cell motility.

21 s, reduced cell proliferation, and increased cell motility.

22 ition nor EGF stimulation have any effect on cell motility.

23 gulates Rac1 transcription to increase tumor cell motility.

24 renal epithelial cells, regulates epithelial cell motility.

25 PAR2 to synergize with TGF-beta1 to promote cell motility.

26 t1KO thyrocytes uniquely displayed a reduced cell motility.

27 n gel contraction assays were used to assess cell motility.

28 mbly, disturbed cell polarity, and increased cell motility.

29 esting that they may cooperate to facilitate cell motility.

30 es cell processes, especially when examining cell motility.

31 focal adhesion traction and, thereby, cancer cell motility.

32 ution to the cortical cytoskeleton and tumor cell motility.

33 lar reversals and leads to severe defects in cell motility.

34 tective role in prostate cancer by impairing cell motility.

35 ay critical roles in the initiation of tumor cell motility.

36 tead was modulated by CB2 agonists to reduce cell motility.

37 ability while concurrently suppressing tumor cell motility.

38 ressing PI3KC2beta activation and its driven cell motility.

39 nces epithelial characteristics and inhibits cell motility.

40 eak calcium fluxes and detectable changes in cell motility.

41 formation of adherens junctions, and reduced cell motility.

42 ial-mesenchymal transition factors and colon cell motility.

43 cellular functions as diverse as memory and cell motility.

44 ers hitherto thought to antagonize efficient cell motility.

45 nd increases membrane protrusion and overall cell motility.

46 red for the ability of GAR22beta to modulate cell motility.

47 ere it is critical for barrier integrity and cell motility.

48 nteracts with HIV Tat to promote endothelial cell motility.

49 increased understanding of their coordinated cell motility.

50 time actomyosin dynamics affects longer-time cell motility.

51 n, promote better understanding of nonmuscle cell motility.

52 sion and contraction dynamics fundamental to cell motility.

53 esis via induction of angiogenesis, AIG, and cell motility.

54 r role in attracting, repelling, or stopping cell motility.

55 midline PSM cells to maintain PSM growth and cell motility.

56 on times longer than the persistence time of cell motility.

57 ng determinants that functionally drive TNBC cell motility.

58 ctin cytoskeleton is an essential feature of cell motility.

59 t may be associated with a phenotype such as cell motility.

60 ity to augment endocytosis or suppress tumor cell motility.

61 cytoskeletal effectors to promote collective cell motility.

62 ding Trio and Tiam2, which were required for cell motility.

63 solely directed towards inhibition of cancer cell motility.

64 Here, we show that mediator of cell motility 1 (Memo1) is a critical determinant of rad

65 T4aP are more widespread and are involved in cell motility(3), DNA transfer(4), host predation(5) and

66 -40 +/- 4%), which ended up to reduction in cell motility (-46 +/- 5%) with inhibition of p-SRC.

67 rease in the persistence of lamellipodia and cell motility, a phenotype consistent with cortactin- an

68 le progression of the parasite is reliant on cell motility, a process driven by myosin A, an unconven

69 However, the role of these proteins in T-cell motility, adhesion, and in vivo trafficking remains

70 leading to PDL1-mediated suppression of TFH cell motility, alteration of TFH cell differentiation, r

71 cal adhesion maturation to enable persistent cell motility and 3D vasculogenesis.

72 opment include changes in integrin-dependent cell motility and adhesion which ultimately help to dete

73 ogy to pathological vascular tufts, abnormal cell motility and altered filopodia dynamics when live-i

74 is involved in the regulation of apoptosis, cell motility and calcium homeostasis.

75 ses, have emerged as important regulators of cell motility and cancer progression.

76 ciated with cellular component organization, cell motility and cell adhesion.

77 ipts of genes involved in nitrogen fixation, cell motility and cell wall synthesis were the most expr

78 ching epithelial end buds, where it enhances cell motility and cell-cell adhesion dynamics.

79 ane protrusions that play essential roles in cell motility and cell-cell communication and act as pre

80 sh-RNA-mediated knockdown of CBL enhanced cell motility and colony formation in NSCLC cells, and t

81 in a wound-healing in vitro assay, impaired cell motility and cytokinesis.

82 ition of ILK signaling, which is involved in cell motility and cytoskeletal reorganization, resulted

83 ay stronger E-cadherin localization, reduced cell motility and decreased dynamics of transient cell s

84 Cell shedding resulted from impaired cell motility and defective cell-cell adhesion, with dam

85 We found that TRM cell motility and dendrite formation required an intact

86 and calpain in the podocyte is important for cell motility and detachment and demonstrates a scaffold

87 n, resulting in upregulation of both general cell motility and directed cell migration, which is in a

88 tumor cells corresponding to increased tumor cell motility and dissemination.

89 ring essential cellular functions, including cell motility and endocytosis.

90 ia-stabilized focal adhesions was restricted cell motility and enhanced attachment to the extracellul

91 ibited cell proliferation, colony formation, cell motility and expression of beta-catenin, Snail, Slu

92 on did not impact cell viability but reduced cell motility and extracellular matrix invasion, as well

93 ding to PlexinD1, thus mediating endothelial cell motility and filopodia retraction.

94 reexpression in GAR22beta(-/-) cells reduced cell motility and focal adhesion turnover.

95 Finally, sublethal doses of CSE reduced cell motility and gel contraction, whereas STE had less

96 GPCRs) to control downstream events, such as cell motility and gene transcription.

97 unclear, although it has been implicated in cell motility and Golgi shape.

98 with a speed determined by the interplay of cell motility and growth, a well-known characteristic of

99 lagellar assembly, but they are required for cell motility and hence infection.

100 This also induced PC3 cancer cell motility and increased colony size in 2D cultures.

101 echanisms of how PRL regulates breast cancer cell motility and invasion are not fully understood.

102 oratory identified PTPN23 as a suppressor of cell motility and invasion in mammary epithelial and bre

103 cells led to enhanced stress fibers, reduced cell motility and invasion into Matrigel.

104 he appropriation of primordial mechanisms of cell motility and invasion, and the influence of multipl

105 een shown to be involved in modulating tumor cell motility and invasion, cancer stem cell viability a

106 suggest that LRIG1 may oppose breast cancer cell motility and invasion, cellular processes that are

107 al targeting of this pathway shuts off tumor cell motility and invasion, kills Myc-expressing cells i

108 ellipodia and podosomes, and thus modulating cell motility and invasion.

109 important factor for Src-mediated increased cell motility and invasion.

110 uld regulate mTORC2-dependent bladder cancer cell motility and invasion.

111 clonogenic colony formation, and the loss of cell motility and invasion.

112 r cells and strongly impairing breast cancer cell motility and invasion.

113 cacy of radiation therapy by curtailing PDAC cell motility and invasion.

114 hibition of GSK3, a kinase for S310, reduced cell motility and invasion.

115 wth and tumor growth in mice, and suppressed cell motility and invasiveness both in vitro and in vivo

116 8 and A172 glioblastoma cell lines increases cell motility and invasiveness in vitro and promotes LN-

117 idine (5-AzaC) potently blocks the increased cell motility and invasiveness induced by Src activation

118 sion changes from wild-type ETV6 and enhance cell motility and invasiveness of TNBC and benign breast

119 xogenous expression suppressed the increased cell motility and invasiveness phenotypes when Src was a

120 Protein kinase D1 (PRKD1) inhibits cell motility and is believed to be dysregulated in panc

121 The actin cytoskeleton drives cell motility and is essential for neuronal development

122 bserved that hypoxic gradients guide sarcoma cell motility and matrix remodeling through hypoxia-indu

123 n of mitochondrial trafficking enables tumor cell motility and metastasis.

124 which disrupts the cytoskeleton to increase cell motility and metastasis.

125 ies PLOD2, which in turn accelerates sarcoma cell motility and metastasis.

126 ytosis, in NME1 and NME2 regulation of tumor cell motility and metastasis.

127 Cell motility and migration requires the reorganization

128 disruption of dAKAP1-PKA complexes affected cell motility and mitochondrial movement toward the lead

129 CD56 in developmental synapse structure, NK cell motility and NK cell development.

130 tress fiber formation to promote endothelial cell motility and permeability.

131 key adhesome members PXN/LPXN limit myeloid cell motility and phagocytosis, thereby providing an imp

132 restraining RAS and PI3-kinase promotion of cell motility and potentially tumour metastasis.

133 On the basis of the key roles of cell motility and proliferation in cancer metastasis, th

134 It inhibits cell motility and promotes S-phase entry by inhibiting t

135 tes differentiation and dramatically impairs cell motility and re-epithelialization.

136 eraction impaired EMT and the acquisition of cell motility and stemness.

137 and collagen I, leading to an impairment in cell motility and survival under both in vitro and in vi

138 tors of integrin-beta3 signaling that affect cell motility and survival, observed during GN in wild-t

139 regulates many cellular processes, including cell motility and survival.

140 wth factor homologue, VGF, promotes infected cell motility and the spread of viral infection.

141 sically slow NMIIB dynamics, thus increasing cell motility and traction and enabling chemotaxis.

142 RAS also regulates cell motility and tumour invasiveness, but the role of d

143 reased LKB1 expression, inhibited individual cell-motility and abrogated the stem-like phenotype of b

144 areas including mechanical microenvironment, cell motility, and cancer biology.

145 active lipid that limits PI3KC2beta-governed cell motility, and ceramide is proposed to serve as a me

146 es, including tumorsphere-forming potential, cell motility, and chemoresistance in vitro, and was suf

147 knowledged to play a role in cell stiffness, cell motility, and cytoplasmic organization, yet it is w

148 s can be employed to control cell viability, cell motility, and cytoskeletal signaling with the high

149 hich suppressed endothelial DLL4 expression, cell motility, and filopodia formation, is expected to b

150 ependent cytoskeletal change, an increase in cell motility, and gain of phagocytic function.

151 skeleton, focal adhesion dynamics, and tumor cell motility, and identify PHIP as a key driver of glio

152 otein superfamily of molecules important for cell motility, and implicated in cancer progression.

153 y implicated in cytoskeleton reorganization, cell motility, and metastatic dissemination.

154 lities for studying intracellular transport, cell motility, and neuronal physiology.

155 cells for glutamine deprivation-induced EMT, cell motility, and nutrient stress survival.

156 ntestinal homeostasis, germline maintenance, cell motility, and proliferation through interactions wi

157 TJ loss increased cell motility, and subsequent AJ loss further up-regulat

158 ons strongly interfered with bleb formation, cell motility, and the ability of the cells to reach the

159 ally, miR-203 suppressed cell proliferation, cell motility, and the angiogenesis-inducing capacity of

160 s outputs might feed back into inputs due to cell motility, and the biological channel can change by

161 ergistic directional forces generated during cell motility are essential for adaptive T-cell immunity

162 The two most prevalent forms of eukaryotic cell motility are flagellar-dependent swimming and actin

163 ive of smallpox virus, is thought to exploit cell motility as a means to enhance the spread of infect

164 acts largely in a paracrine manner to direct cell motility at the leading edge of infection.

165 g the balance between cell proliferation and cell motility, but the regulators of this process are la

166 ns, the purinergic A2b receptor can regulate cell motility, but the underlying mechanism remains unkn

167 Messenger RNA localization is important for cell motility by local protein translation.

168 nd open the possibility that CRMP-1 controls cell motility by modulating Arp2/3 activation.

169 gulates nuclear size, nuclear integrity, and cell motility by perturbing nuclear flux homeostasis via

170 vation prevented immune cell recruitment and cell motility by reducing the expression levels of the r

171 cipates in Slit2/Robo1 signaling to modulate cell motility by regulating Cdc42 activity.

172 otes matrix metalloproteinase-2 activity and cell motility by ROS-activated c-Jun N-terminal kinase p

173 suggest that fluid motion due to outer hair cell motility can help maintain longitudinal homeostasis

174 assium ion concentration; second, outer hair cell motility causes organ of Corti deformations that al

175 s-dependent transcriptomic changes affecting cell motility, cell adhesion, and cytoskeleton organizat

176 ment of numerous cellular processes, such as cell motility, cell division and endocytosis.

177 or, such as cell morphology, cell mechanics, cell motility, cell signaling, all of which can potentia

178 lls related to Wnt signaling, including high cell motility, cell-cycle progression, and the overexpre

179 ssion, whereas increased tissue rigidity and cell motility/contractility help mediate tumour progress

180 ter, and argue that persistent uncoordinated cell motility coupled to the collective elastic modes of

181 hat loss of PACRG and/or FAP20 causes severe cell motility defects and reduced in vitro microtubule s

182 Cell motility depends on tight coordination between the

183 allmarks: apoptosis, cell cycle, cell death, cell motility, DNA repair, immune response, two phosphor

184 an NKF3 family member with a unique role in cell motility driven by dimerization of its pseudokinase

185 g protein whose normal function is to enable cell motility during development of tissues and organs o

186 a with a specific focus on their impact on T cell motility during influenza virus infection.

187 erve as a multi-step mechanism to coordinate cell motility during migration.

188 simulations that incorporate accurate immune cell motility dynamics.

189 s essential for biological functions such as cell motility, embryonic development, and muscle contrac

190 ic reticulum-associated protein degradation, cell motility, endocytosis, and endocytic recycling of m

191 s, Persistent Random Walk, we found that the cell motility estimates among six cell lines used in thi

192 te behaviors, we show that no differences in cell motility exist among cell types and that sorting dy

193 e, which is further enhanced by acid-induced cell motility, extracellular matrix degradation, attenua

194 I1, which together with other EVI1-dependent cell motility factors such as RHOJ regulated breast carc

195 ves that are predicted to be associated with cell motility for follow-up experiments.

196 plicative histones, ribosomal biogenesis and cell motility functions.

197 es; and (iii) nervous system development and cell motility genes in right-lateralized structures.

198 First, a cell motility gradient drives paraxial presomitic mesode

199 Endothelial cell motility has fundamental role in vasculogenesis and

200 ate nuclear shape and perinuclear stiffness, cell motility in 3D, and the ability of cells to resist

201 Notably, both light and H2O2 enhance T-cell motility in a Lck-dependent manner.

202 regulate cytoskeletal signaling pathways and cell motility in cells outside the nervous system.

203 ights into the mechanisms controlling immune cell motility in complex tissue environments.

204 candidate therapeutic targets to manipulate cell motility in disease or tissue regeneration.

205 ults shed new light on in-bulk myosin-driven cell motility in living cells and provide a framework to

206 he dominant cause of dysregulated infected T cell motility in lymphoid tissue by preventing stable ce

207 Directed migration is essential for cell motility in many processes, including development a

208 d that HuR was required for the promotion of cell motility in migrating neurons.

209 The computer-assisted analysis of cell motility in mixed suspensions showed that the swimm

210 which has recently been reported to control cell motility in monocytes, alongside reduced VLA-4 expr

211 ctions of PLK1 as a key regulator of EMT and cell motility in normal prostate epithelium and prostate

212 ng of the ECM leads to both cell cycling and cell motility in serum-stimulated primary mouse dermal f

213 utes to contractility of striated muscle and cell motility in several contexts.

214 5HMF, 5NFA, and 5AMF selectively impaired cell motility in the AQP1-enriched cell lines.

215 ongation of the embryonic axis by regulating cell motility in the presomitic mesoderm and by controll

216 ty, we show that spontaneous pauses during T cell motility in vitro and in vivo coincide with episode

217 umor-secreted cytokine that stimulates tumor cell motility in vitro and metastasis in vivo.

218 omes were employed and confirmed to suppress cell motility in vitro.

219 ominent increases in [Ca(2+) ]i and promotes cell motility in wound healing and transwell migration a

220 cally host partners of a network relevant to cell motility, including liprin-alpha1, which was unnece

221 artners, we identified several regulators of cell motility, including the adaptor protein CrkII.

222 se inhibitor, thereby inhibiting endothelial cell motility, independently of pore function.

223 11L alone is not sufficient for VACV-induced cell motility, indicating that additional viral factors

224 Our modeling method indicated that decreased cell motility inside the aggregates, a biased walk towar

225 regulating many cellular functions including cell motility, intercellular and intracellular signaling

226 sin motor proteins that drive cell division, cell motility, intracellular trafficking and ciliary fun

227 of the PI3K-AKT pathway in the regulation of cell motility, invasion and metastasis.

228 gain of function mutant p53 promotes cancer cell motility, invasion, and metastasis.

229 d functions in integrin signaling to promote cell motility, invasion, proliferation, and survival.

230 tion of v-Src kinase, resulting in increased cell motility, invasiveness, and tumorigenicity and prov

231 ch as the epithelial-mesenchymal transition, cell motility, invasiveness, angiogenesis, and metastasi

232 migration patterns, suggesting that aberrant cell motility is a phenotype for these neurological dise

233 Enhanced TNBC cell motility is a prerequisite of TNBC cell disseminati

234 One factor that affects cell motility is cell mechanics, which is known to be re

235 Battling metastasis through inhibition of cell motility is considered a promising approach to supp

236 Cell motility is essential for viral dissemination(1).

237 We present clear evidence that cell motility is independent of the cell-cycle phase and

238 sm by which TGF-beta signaling converts into cell motility is not completely understood.

239 However, it is not known whether cell motility is regulated by global or local inhibition

240 Cell motility is required for diverse biological process

241 We propose that vimentin's role in cell motility is to govern the alignment of traction str

242 Whilst the role of vinculin in cell motility is well established, it remains unclear ho

243 In addition, U251 cell motility is ~2-fold higher in gray matter than in w

244 uitment of follower cells but not for leader cell motility itself, which instead utilizes focal adhes

245 tigations showed that MCPIP1 regulated ccRCC cell motility, lung metastasis, and mesenchymal phenotyp

246 al mechanistic studies, we found that cancer cell motility mediated by the actin-related protein 2/3

247 ologue of mammalian mediator of ErbB2-driven cell motility, MEMO-1, as a protein that inhibits BLI-3/

248 normal colorectal epithelial cells increased cell motility, migration and invasion, which were associ

249 ary for understanding how vinculin regulates cell motility, migration, and wound healing, and for und

250 cer metastasis, and regulatory mechanisms of cell motility need to be uncovered for developing novel

251 biochemical signaling, membrane traffic, and cell motility, originate at membrane surfaces.

252 triggering matrix digestion, and subsequent cell motility permits escape from biofilms.

253 quantitative image analysis to characterize cell motility phenotypes in culture.

254 es regulate diverse cellular events, such as cell motility, polarity, and vesicle traffic.

255 e an important new biological application of cell motility principles.

256 (OR), a planar cell polarity (PCP)-mediated cell motility process.

257 variant in a TP53-null cell line, it induced cell motility, proliferation, and invasion compared with

258 Ceramide treatment also suppressed cell motility promoted by epithelial growth factor, whic

259 Previously we reported that engulfment and cell motility protein 1 (ELMO1) in macrophages mediates

260 ic for RAC, and require ELMO (engulfment and cell motility) proteins for function.

261 ssion analyses showed that regulation of the cell motility receptor RHAMM by the RB/E2F pathway was c

262 hypotheses about these genes’ role in cell motility regulation, offering a framework for gener

263 made by HGF signalling to pancreatic cancer cell motility remain to be elucidated.

264 Cell motility requires the precise coordination of cell

265 Cilia and flagella play essential roles in cell motility, sensing and development.

266 broad range of cellular functions, including cell motility, signal transduction, and virus replicatio

267 ed membrane fluidity, resulting in decreased cell motility, stem cell-like properties, and EMT in vit

268 Interpretation of cell motility studies though is often restricted by the

269 Previous studies focusing on T cell motility suggested that the activation of naive T c

270 y and may be applicable in a wide variety of cell motility systems.

271 , bioaccumulation and deleterious effects on cell motility systems.

272 dence that Cdc42EP5 is a regulator of cancer cell motility that coordinates actin and septin networks

273 mechanism of adhesion-protrusion coupling in cell motility that involves dynamic regulation of Pfn1 b

274 lipid membranes in endocytosis, trafficking, cell motility, the formation of complex subcellular stru

275 n independently control different aspects of cell motility: the static component controls swimming di

276 ostate cancer cells in vitro, inducing tumor cell motility through a nonproteolytic signal transducti

277 e signaling mechanism by which RSK2 promotes cell motility through leukemia-associated RhoGEF (LARG)-

278 evealed a key role for IHF as a repressor of cell motility through the control of FliA sigma factor e

279 ack epidermal growth factor receptor-induced cell motility to promote rapid and efficient spread of i

280 rs cell migration directionality, leading to cell motility toward concave regions of the substrate, r

281 ost important part in metabolism, signaling, cell motility, transport, development, and many other bi

282 lung TIC phenotypes, including tumorspheres, cell motility, tumorigenesis, as well as in vitro and in

283 t of extracellular DNA, kin recognition, and cell motility (twitching).

284 vasiveness, in part, by disrupting polarized cell motility under confinement and cell chemotaxis.

285 at regulates fibrinolysis, cell adhesion and cell motility via its interactions with plasminogen acti

286 of RhoA and Cdc42 GTPases and also regulates cell motility via the modulation of well-known molecules

287 -substrate impedance sensing system, whereas cell motility was assessed using the scratch test and co

288 Cell motility was inversely associated with only 12.5% m

289 that links cell mechanics to cell shape and cell motility, we formulate a generalized mechanical inf

290 me monitoring of cytosolic Ca(2+) along with cell motility, we show that spontaneous pauses during T

291 idification also increased mammary carcinoma cell motility when cultured with fibroblasts in spheroid

292 reas this would normally physically restrict cell motility, when the particulate network is created u

293 ovel role for Nischarin in preventing cancer cell motility, which contributes to our understanding of

294 to determine the effect of FAK inhibition on cell motility, which decreased significantly in both cel

295 ulation induces TGF-beta signaling, EMT, and cell motility, which is effectively blocked by the TGF-b

296 Targeting cell motility, which is required for dissemination and m

297 ely accepted as a prerequisite for mammalian cell motility, which precludes swimming.

298 contractility is further found to limit the cells motility, which (i) decelerates the wave speed and

299 ic Mena11a expression slows mesenchymal-like cell motility, while isoform-specific depletion of endog

300 inosa transitioned from collective to single-cell motility with an associated increase in speed and d