ライフサイエンスコーパス: cell-derived

1 Egg- and cell-derived 2018-2019 season influenza vaccines elicite

2 ls, and primary and induced pluripotent stem cell-derived(6) hematopoietic stem progenitor cells (HSP

3 luenza season were measured against egg- and cell-derived A/Singapore/INFIMH-16-0019/2016-like and ci

4 ct of dilution on the EM of U87 glioblastoma cell-derived and plasma-derived sEVs and medium size EVs

5 ells and promote their stemness, endothelial cell-derived angiocrine signals orchestrate a favorable

6 Mechanistically, myeloid cell-derived angiogenin promoted IEC survival and prolif

7 in the tumor microenvironment and that tumor cell-derived ANGPT2 augments metastatic colonization by

8 Autoreactive B cell-derived antibodies form immune complexes that likel

9 of Clec9A and the cross-presentation of dead cell-derived antigens by mouse dendritic cells.

10 ceptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the ind

11 duced AHN deficits but increased neural stem cell-derived astrogliosis, associating with a downregula

12 proteomic survey of induced pluripotent stem cell-derived AT2s (iAT2s) infected with SARS-CoV-2 at ai

13 SARS-CoV-2 by using induced pluripotent stem cell-derived AT2s that have been adapted to air-liquid i

14 e fraction from MYL4-/- human embryonic stem cell derived atrial cells demonstrated increased phospho

15 otocol for generating human pluripotent stem-cell-derived beta (SC-beta) cells with improved in vitro

16 vered from transplanted human embryonic stem cell-derived beta cells.

17 eta-like cells produced from human embryonic cell-derived beta-cell clusters.

18 ell lines and human induced pluripotent stem cell-derived beta-like cells.

19 gement across human induced pluripotent stem cell-derived brain endothelial-like cells.

20 Over the past decade, human stem cell-derived brain organoids have emerged as a biologica

21 Here, we use human-pluripotent-stem-cell-derived brain organoids to examine SARS-CoV-2 neuro

22 conducted in human induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CM) demonstrated th

23 ssion) and in human-induced pluripotent stem cell-derived cardiac myocytes deficient in SCN5A.

24 il strategies for driving maturation of stem cell-derived cardiac myocytes.

25 cellular potential of human pluripotent stem cell derived cardiomyocyte cells (hPSCs-CMs) for several

26 t advances in human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology and by

27 ead to better maturation of pluripotent stem cell-derived cardiomyocyte and novel therapeutic strateg

28 o the maturation defects in pluripotent stem cell-derived cardiomyocyte, its antagonistic effect on m

29 phenotype of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) is a major limit

30 experiments showed that human embryonic stem cell-derived cardiomyocytes (hESC-CMs) contain nodal-lik

31 modulators to human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in vitro can exp

32 Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide an excel

33 cells and in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), and we describe

34 omyocytes and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), but potentiated

35 cardiomyocytes, using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) as the target of

36 rdioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been propose

37 ously reported that induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from patients wit

38 The development of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) signifies an impo

39 ry limitation in the use of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) for both patient h

40 Pluripotent stem cell-derived cardiomyocytes (PSC-CMs) hold great promise

41 ouse cardiomyocytes and human embryonic stem cell-derived cardiomyocytes are considerably enhanced up

42 emergence of human induced pluripotent stem cell-derived cardiomyocytes as an in vitro research tool

43 vidence suggests that human pluripotent stem cell-derived cardiomyocytes can affect "heart regenerati

44 Genome-editing in human embryonic stem cell-derived cardiomyocytes confirms the influence of th

45 al studies on human induced pluripotent stem cell-derived cardiomyocytes demonstrated that the anti-L

46 ate and highly purify human pluripotent stem cell-derived cardiomyocytes displaying physiological and

47 in patient-specific induced pluripotent stem cell-derived cardiomyocytes from NS patients carrying bi

48 pregulated in human-induced pluripotent stem cell-derived cardiomyocytes from patients with doxorubic

49 Using human induced pluripotent stem cell-derived cardiomyocytes in cardiac microtissue and s

50 We generated induced pluripotent stem cell-derived cardiomyocytes of the affected siblings and

51 Patients' induced pluripotent stem cell-derived cardiomyocytes recapitulated the hypertroph

52 Inactivating LMNB2 in human iPS cell-derived cardiomyocytes reduced karyokinesis and inc

53 Here, we use primate pluripotent stem-cell-derived cardiomyocytes that mimic fetal cardiomyocy

54 m channels in human induced pluripotent stem cell-derived cardiomyocytes using a high throughput auto

55 In human induced pluripotent stem cell-derived cardiomyocytes, GS-967 and eleclazine cause

56 (LQTS2) using human induced pluripotent stem cell-derived cardiomyocytes, KCNQ1 antibodies reverse th

57 recorded from human induced pluripotent stem cell-derived cardiomyocytes.

58 potential in human-induced pluripotent stem cell-derived cardiomyocytes.

59 t and control human induced pluripotent stem cell-derived cardiomyocytes.

60 omyocytes and human induced pluripotent stem cell-derived cardiomyocytes.

61 from knockout human induced pluripotent stem cell-derived cardiomyocytes.

62 2:p.R286H iPSC-CMs (induced pluripotent stem cells derived cardiomyocytes) show hypercontractility, i

63 ry studies in human induced pluripotent stem cell derived-cardiomyocytes reveal Cx43 gap junction rem

64 In particular, mural-cell-derived CCL2 stimulates tumor cell MEK1-ERK1/2-ROCK

65 future therapies using bone-marrow- or stem-cell-derived cells for the treatment of neurological dis

66 extensive plasticity of SMC- and endothelial cell-derived cells including 7 distinct clusters, most n

67 al range, regulation, and role of effector T cell-derived chemokines remains incompletely understood.

68 lines, primary astrocytes and embryonic stem cell-derived cortical interneurons.

69 grafted human induced pluripotent stem (iPS) cell-derived cortical neurons send widespread axonal pro

70 tamye) mice were injected with these myeloid cell-derived cytokines, intestinal tissues increased pro

71 t monocyte-derived cytokines, but not with T cell-derived cytokines.

72 The epithelial cell-derived danger signal mediators thymic stromal lymp

73 ouse embryonic stem cells and embryonic stem cell-derived definitive endoderm cells, screening 7905 d

74 the first time that induced pluripotent stem cell-derived dendritic cells (iPS-DCs) with biallelic mu

75 Induced pluripotent stem cell-derived dopaminergic cultures reveal a signature in

76 ion and toxicity in induced pluripotent stem cell-derived dopaminergic cultures treated with PD brain

77 skin fibroblasts or induced pluripotent stem cell-derived dopaminergic neurons.

78 CM maturation to a greater extent than mouse cell derived ECM.

79 Yet, the contribution of cancer cell-derived ECM and tumor mechanics to drug adaptation

80 ant upregulation of Quaking-7 (QKI-7) in iPS cell-derived ECs when exposed to hyperglycemia, and in h

81 (TNFalpha inflamed mouse cardiac endothelial cell-derived exosome).

82 y immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exo

83 noma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX).

84 tor-alpha)-treated mouse cardiac endothelial cell-derived exosomes (TNFalpha inflamed mouse cardiac e

85 Biogenesis, secretion, and uptake of immune cell-derived exosomes are regulated by intracellular pro

86 Immune cell-derived exosomes can mediate crosstalk between inna

87 Schwann cell-derived exosomes communicate with dorsal root gangl

88 However, the role of beta-cell-derived exosomes in metabolic homeostasis is poorly

89 The dichotomous roles of immune cell-derived exosomes towards tumor cells can induce sup

90 psulation and controlled, tunable release of cell-derived exosomes, which maintains their advantageou

91 urate methods to analyze the different NSCLC cells-derived exosomes.

92 ted the hypothesis that human perinatal stem cell derived extracellular matrix (ECM) promotes hiPSC-C

93 Osteolineage cell-derived extracellular vesicles (EVs) play a regulat

94 Bone marrow mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), which med

95 rgo contained within or excluded from cancer cell-derived extracellular vesicles, supporting their ro

96 lar endothelial growth factor (VEGF)-stromal cell-derived factor 1 (sdf1) signaling, leading to lack

97 y orosphere assays revealed that endothelial cell-derived factors (e.g., interleukin-6 [IL-6]) promot

98 terologous communication hubs in which tumor cell-derived factors modify the cross-talk between EC su

99 terologous communication hubs in which tumor cell-derived factors modify the cross-talk between LSECs

100 thermore, we introduce a mesenchymal stromal cell derived from human olfactory tissue, which has the

101 we describe TZM-gfp, a novel HIV-1 reporter cell derived from the same parental clone JC.53, used pr

102 In this study, both induced pluripotent stem cells derived from a MFS-patient and the line with the c

103 ively applied to FACS analysis of microglial cells derived from a mouse model relevant to Alzheimer's

104 nscriptome analysis on Mecp2-null models and cells derived from a patient with RTT, confirming that t

105 Cells derived from affected individuals showed normal ci

106 differentiated from induced pluripotent stem cells derived from an affected individual showed reduced

107 e (PD) tissue sources: (a) neural progenitor cells derived from an endogenous adult stem/progenitor c

108 whereby human endothelial and smooth muscle cells derived from blood progenitors from the same donor

109 fore, here we tested the ability of the stem cells derived from bone marrow (BMSC), dental pulp (DPSC

110 Myeloid cells derived from bone marrow contribute to the formati

111 Among cells derived from breast milk of additional ten women n

112 approach to identify the Zta-interactome in cells derived from Burkitt's lymphoma.

113 ated gliadin reactive HLA-DQ2.5-restricted T cells derived from CeD patients.

114 administered HLA-mismatched anti-CD19 CAR-NK cells derived from cord blood to 11 patients with relaps

115 py number profiles revealed that malignant B cells derived from different patients with VRL had no co

116 s non-canonical pathway in human endothelial cells derived from different vascular beds.

117 ic islet cells such as alpha-cells, or other cells derived from endoderm); the engineering of non-bet

118 stance to sorafenib or cisplatin in HCC stem cells derived from four HCC cell lines.

119 stalling and can be observed also in primary cells derived from gastric organoids.

120 Taken together, we demonstrate that NES cells derived from Gorlin patients can be used as a reso

121 in situ hybridization (smFISH) on mouse stem cells derived from haematopoietic tissue to measure the

122 reactive oxygen species, in CD33(+) myeloid cells derived from hepatitis C virus (HCV)-infected pati

123 hotopic engraftment of the neural progenitor cells derived from hiPSCs that have been genome-edited t

124 We administered renal tubule-forming cells derived from human adult and fetal kidneys (previo

125 and functionally similar to trophoblast stem cells derived from human blastocysts or first-trimester

126 aracterized and compared in mesenchymal stem cells derived from human dental pulp (DP-MSCs) and bone

127 re, we demonstrated that culture of EpCAM(+) cells derived from human induced pluripotent stem cells

128 ression in human cell line models and neural cells derived from human iPSCs, and induced histone (H)3

129 Consistent with mouse models, myeloid cells derived from human peripheral blood monocytes acti

130 ood mononuclear cells, or immature dendritic cells derived from human peripheral blood mononuclear ce

131 Mas-are expressed in vasculogenic progenitor cells derived from humans and rodents.

132 lation and associated telomeric functions in cells derived from ICF1 model mice.

133 r cells (MDSCs) are a group of heterogeneous cells derived from immature myeloid cells (IMCs).

134 mponents, and transcriptomic clustering with cells derived from individuals with closely related cili

135 CD4+ T cells derived from individuals with latent Mtb infection

136 e viral replication in human pneumocyte-like cells derived from induced pluripotent stem cells, and a

137 Physiologic maturation of neuronal cells derived from isolated stem or progenitor cells may

138 did not affect circadian rhythms in cultured cells derived from luminescent reporter embryos or in es

139 ovarian cancer cell detachment and in tumor cells derived from malignant ascites of high-grade serou

140 oss an isogenic panel of human breast cancer cells derived from MDA-MB-231 cells.

141 Cells derived from milk from the breast with cancer were

142 mental profiles of serum and sorted immune T cells derived from naive and tumor-bearing mice.

143 ltures of primary human bronchial epithelial cells derived from non-asthmatic donors and asthmatic do

144 this study we use cultured neural progenitor cells derived from olfactory neuroepithelium (CNON cells

145 ences OTX2 gene editing on the population of cells derived from OTX2-expressing retinal progenitor ce

146 ments using recombinant TSP4 variants and in cells derived from P387-TSP4 knock-in mice.

147 re, we show that succinyl-CoA accumulates in cells derived from patients with recessive mutations in

148 We then tested a promising candidate in cells derived from patients with, and mouse models of, c

149 nt hydrogel, effectively killing primary GBM cells derived from patients.

150 The outgrown cells derived from PDL and gingival tissues were similar

151 te-derived dendritic cells (DCs), Vdelta2(+) cells derived from peripheral blood rapidly upregulate C

152 -dimensional (3D) culture technique for hAT2 cells derived from primary human lung tissue and investi

153 ting polarized Th1/Th17 cells or CCR6+CLA+ T cells derived from psoriasis patients into the construct

154 he transcriptomes of more than 20 000 single cells derived from root tips of two agronomically import

155 increase of RLIM mRNA and protein levels in cells derived from seven affected males from five famili

156 s, CD8+ T-cell responses were confirmed in T cells derived from several mumps cases, and MuV-specific

157 ChIP-Seq analysis of bone marrow cells derived from six acute myeloid leukemia (AML) pati

158 This is the first study to use cells derived from skeletal muscle biopsies in CFS patie

159 ss cytometry of 28 PTMs in >1 million single cells derived from small intestinal organoids reveals ce

160 The CRRC results of the dispersed-settled cells derived from spheroids are compared to those of sp

161 For dendritic cells derived from STING-deficient mice, no activation w

162 In LUAD cells derived from surfactant protein C expressing proge

163 s from cutaneous MF tumors as well as Sezary cells derived from the blood of SS patients, we demonstr

164 258 uptake was rarely observed in epithelial cells derived from the ectocervix and transformation zon

165 We have demonstrated that meniscal cells derived from the lateral meniscus in medial OA pat

166 We introduce dynamic signatures of cells derived from the LD displacement, speed, travel le

167 vealed that CD4(+) effector memory T (T(EM)) cells derived from the lymph node appeared to contain pr

168 brafish we have previously demonstrated that cells derived from the periderm penetrate the oropharyng

169 Tumor organoid cells derived from the TACSTD2(high) luminal cells are m

170 omic profiling of cortical neural progenitor cells derived from these hiPSCs identified alterations i

171 ed using biomatrices and bulk populations of cells derived from tissues or cell lines.

172 ificantly higher level on avascular meniscal cells derived from tissues with a more degenerated inner

173 ce, and W/W(V) mice given injections of mast cells derived from wild-type or Ptgs2(Y385F) mice.

174 oligomer was chosen to treat forced-myogenic cells, derived from fibroblasts from nine patients carry

175 ults demonstrate that human pluripotent stem cell-derived glomeruli can develop an appropriate barrie

176 Taken together, we uncover T cell-derived GM-CSF as a key inducer of the chemokine CC

177 lted in CCL22 secretion, and we identified T cell-derived GM-CSF as the major inducer of DC-derived C

178 n medicine, even when using pluripotent stem cell-derived grafts.

179 Human stem cell-derived hepatocyte-like cells (HLCs) offer an attra

180 y human hepatocytes (PHHs), pluripotent stem cell-derived hepatocyte-like cells (HLCs), and hepatoma

181 esence of concurrent donor-specific memory B cell-derived HLA antibodies (DSA-M) in renal allograft r

182 of AD patients, in induced pluripotent stem cell-derived human AD neurons, and in animal AD models.

183 ither endobronchial induced pluripotent stem cell-derived human MSCs (hMSCs) (n = 7) or cell-free car

184 a model using Induced pluripotent stem (iPS) cell-derived human neuroepithelial stem (NES) cells gene

185 Here we report on the generation of stem cell-derived human pancreatic alpha (SC-alpha) cells fro

186 iggering pattern recognition receptors and T cell-derived IFN-gamma production.

187 lular target and downstream effects of CD8 T cell-derived IFN-gamma remains poorly understood.

188 Egg- and cell-derived IIVs elicited responses similar to each oth

189 Ablation of T cell-derived IL-10 increased the IFN-gamma and IL-17A re

190 Mast cell-derived IL-13 was required for induction of AAMPhi,

191 hese findings reveal the essential role of B cell-derived IL-1beta and IL-6 during homeostatic T cell

192 ole of myeloid- versus intestinal epithelial cell-derived IL-33 during dextran sodium sulfate-induced

193 prisingly, the lack of intestinal epithelial cell-derived IL-33 had no impact on disease severity or

194 litic disease, whereas intestinal epithelial cell-derived IL-33 is dispensable.

195 Meanwhile, myeloid cell-derived IL-33 was required for airway inflammation,

196 nistic studies demonstrated that endothelial cell-derived IL-6 activates IL-6R (IL-6 Receptor) and si

197 sive responses by polarizing AAMPhi via mast cell-derived IL-6 and IL-13.

198 quired for induction of AAMPhi, whereas mast cell-derived IL-6 enhanced macrophage responsiveness to

199 ely, these data demonstrate that endothelial cell-derived IL-6 enhances the self-renewal of dental pu

200 Loss of tumor cell-derived IL1 signaling in tumor stroma enabled intra

201 tify a hitherto unappreciated role for tumor cell-derived IL1beta in orchestrating an immune-modulato

202 Tumor cell-derived IL1beta promoted the activation and secreto

203 Dendritic cells derived in vitro from MDS monocytes failed to deve

204 Here we show that human PSM cells derived in vitro-as well as those of the mouse(4)-

205 s comparing recombinant HA vaccine (rHA) and cell-derived inactivated influenza vaccine (IIV) to egg-

206 influenza season, quadrivalent, inactivated cell-derived influenza vaccine (ccIIV4) vaccine was prod

207 This result suggests that cell-derived influenza vaccines may have greater effecti

208 a niche in the neonatal airway where stromal cell-derived insulin-like growth factor 1 (IGF1) support

209 have recovered from WNV or ZIKV infection, T cell-derived interferon-gamma (IFN-gamma) signaling in m

210 Endothelial cell-derived interleukin-18 (IL-18) selectively expands

211 ILC2 activation requires tuft-cell-derived interleukin-25 (IL-25), but whether additio

212 In mouse xenograft studies, human stem cell-derived-interneuron precursors could differentiate

213 Transplantation of human stem cell-derived interneurons is a promising cell-based ther

214 Loss of YIPF5 function in stem cell-derived islet cells resulted in proinsulin retentio

215 Replacing beta cells using stem cell-derived islets while fostering immune tolerance, ex

216 a suggest that downregulation of mesothelial cell-derived ITLN1 in the omental tumor microenvironment

217 eability of a single-dose, inactivated, Vero-cell derived, JENVAC to the live-attenuated SA 14-14-2 v

218 sequent maturation of human pluripotent stem cell-derived kidney organoids after renal subcapsular tr

219 n in the transplanted human pluripotent stem cell-derived kidney tissue 1, 2, and 3 weeks after trans

220 These findings suggest that tumor cell-derived lactate activates GPR81 in dendritic cells

221 ocrine role to promote tumor growth by tumor cell-derived lactate.

222 oligomerization of transmembrane proteins in cell-derived lipid membranes.

223 ary mouse and human induced pluripotent stem cell-derived lung epithelial cells to model early-stage

224 rol matrices (VehMs), glucocorticoid-induced cell-derived matrices (GIMs) trigger non-Smad TGFbeta2 s

225 s study provides strong evidence that cancer cell-derived matrisome proteins can be causal in promoti

226 insights into the biological roles of cancer cell-derived matrisome proteins in PDAC and supports the

227 Here, we studied three cancer cell-derived matrisome proteins that are significantly o

228 ells, precise interventions targeting cancer cell-derived matrisome proteins, such as AGRN, SERPINB5,

229 Using induced pluripotent stem cell-derived megakaryocyte clones that produce functiona

230 e binding of proteins and small molecules to cell-derived membranes and the permeation of drug-like m

231 (22q) result in meningiomas in neural-crest cell-derived meninges, while variants affecting Hedgehog

232 levels are both upregulated in neural crest cell-derived mesenchyme surrounding Meckel's cartilage a

233 ly engineered human induced pluripotent stem cell-derived microglia-like cells to show that TREM2 sig

234 ely post-intravenous injection, but numerous cell-derived microparticles continued to circulate in bl

235 Storage lesion-induced, red cell-derived microvesicles (RBC-MVs) propagate coagulati

236 T-cell-derived miR-214 controls pathological perivascular

237 ken together, our study illustrates how stem cell derived models can be used to uncover and rescue ce

238 Advances in stem cell-derived models of human organogenesis, in the form

239 Indeed, previous human pluripotent stem-cell-derived models of kidney tissue either contain neph

240 However, the omental cell-derived molecular determinants modulating its progr

241 rotracted muscle regeneration, and satellite cell-derived myogenic cells from EphA7(-/-) mice are del

242 ive diseases/lymphomas as well as epithelial cell-derived nasopharyngeal cell carcinoma.

243 nia, and studies of induced pluripotent stem cell-derived neural progenitor cells.

244 CDKL5-mutant human induced pluripotent stem cell-derived neural progenitors, which were subsequently

245 h disease patients' induced pluripotent stem cells-derived neural stem cells incubated with ibuprofen

246 and our own mouse hippocampal and human stem cell-derived neuron PAC-seq data-strongly supports the v

247 al cortex (PFC) and induced pluripotent stem cell-derived neuronal cultures from patients with schizo

248 olated from C9orf72 induced pluripotent stem-cell-derived neurons (iPSNs).

249 nipulation in human induced pluripotent stem cell-derived neurons and RNAi-based knockdown in Drosoph

250 c analyses on human induced pluripotent stem cell-derived neurons at 22, 50 and 78 days (D) post-diff

251 ter stroke in animal models but whether stem cell-derived neurons become functionally integrated into

252 ccumulated in human induced pluripotent stem cell-derived neurons depleted of TDP-43, but not in thos

253 excitatory neurons, induced pluripotent stem cell-derived neurons from all three patients displayed a

254 and CTSB and GBA p.N370S induced pluripotent cell-derived neurons were shown to have decreased cathep

255 On human induced pluripotent stem cell-derived neurons, the nanobody prevents C3 depositio

256 g proteins in human induced pluripotent stem cell-derived neurons.

257 ase phenotypes in SCA7 mice and patient stem cell-derived neurons.

258 viability of human induced pluripotent stem cell-derived neurons.

259 glioma cells and in induced pluripotent stem cell-derived neurons.

260 use AD models and genome-edited human AD iPS cell-derived neurons.

261 zing isogenic human-induced pluripotent stem cells-derived neurons from PD patients with autosomal do

262 We studied whether administration of glial cell derived neurotrophic factor (GDNF) induces enteric

263 The effects of neither glial cell-derived neurotrophic factor (GDNF) nor serotonin ar

264 brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor and release axon-guidan

265 le source for human induced pluripotent stem cell-derived NK (hnCD16-iNK) cells.

266 ) NK cells using an induced pluripotent stem cell-derived NK cell (iPSC-NK cell) platform.

267 K cells, umbilical cord blood NK cells, stem cell-derived NK cells, NK cell lines, adaptive NK cells,

268 This property was dependent on stroma cell-derived Notch ligands.

269 e presence and quantity of circulating tumor cell-derived nucleases.

270 ronic HIF1a accumulation in pluripotent-stem-cell-derived oligodendrocyte progenitors (OPCs), we demo

271 Stem cell-derived organoid models have emerged as a valuable

272 xacillin and in primary hepatocytes and stem cell-derived organoids from multiple donors treated with

273 These results indicate that immune cell-derived oxidants generated during inflammation have

274 effector T-cell responses to pancreatic beta-cell-derived peptides presented by HLA class I and class

275 have previously demonstrated peritoneal B-1a cell-derived phosphorylcholine-specific and total IgM mo

276 Here, we demonstrate that PDA tumor cell-derived proinflammatory cytokine IL1beta is essenti

277 protocol to generate human pluripotent stem cell-derived Purkinje cells (hPSC-PCs) that formed synap

278 out half of all foam cells are smooth muscle cell-derived, retaining smooth muscle cell transcripts r

279 otein kinase inhibitor library in human stem cell-derived retinal ganglion cells (hRGCs).

280 sing clinical-grade induced pluripotent stem cell-derived retinal pigment epithelial cells (iPSC-RPE)

281 Here, we utilized induced pluripotent stem cell-derived retinal pigment epithelium (iPSC-RPE) to te

282 ddressing a major issue in the field of stem cell-derived retinas.

283 er validating the disappearance of apoptotic cell-derived RNA sequences.

284 rative medicine approaches that utilise stem cell-derived RPE cells to treat conditions such as age-r

285 n using sequencing on human pluripotent stem cell-derived SAN-like pacemaker cells and ventricle-like

286 We found that human induced pluripotent stem cell-derived sensory neurons expressed the receptor for

287 Dmd C3333Y animals, induced-pluripotent-stem-cell-derived skeletal muscle cells from patients with Be

288 d unique surface properties of breast cancer cell-derived small EVs (sEV) obtained using four differe

289 ally depends on B cells and is mediated by B cell-derived soluble factors.

290 In conclusion, this work provides a unique cell-derived system generating spontaneous prions and pr

291 eactivity of a 'public', HIV-specific, CD8 T cell-derived TCR (AGA1 TCR) using MHC class I yeast disp

292 e results identify a privileged role of Treg cell-derived TGF-beta1 in regulating allergy and autoimm

293 In this study, we demonstrate that myeloid cell-derived TGF-beta1 signaling is increased in a profi

294 ls, which have several advantages over fetal cell-derived therapies.

295 dress major safety concerns with pluripotent cell-derived therapies.

296 Stem-cell-derived tissues could transform disease research an

297 transplantation of induced pluripotent stem cell derived TM like cells (iPSC-TM) restores TM cellula

298 ters and response rates, indicating that the cell-derived vaccine did not improve immunogenicity agai

299 tivity in endothelial cells targeted by mast cell-derived vasoactive substances.

300 luids often within exosomes, which are small cell-derived vesicles that function in intercellular com