ライフサイエンスコーパス: cell-mediated immunity

1 both neutralizing antibodies and protective cell mediated immunity.

2 d to provide convincing evidence of improved cell mediated immunity.

3 not influence their ability to orchestrate T cell-mediated immunity.

4 ase-modifying treatments in MS that affect T-cell-mediated immunity.

5 eonate is attributed in part to defects in T cell-mediated immunity.

6 e-MHC (pMHC) on cells is a key parameter for cell-mediated immunity.

7 r contributing to the observed loss in CD8 T cell-mediated immunity.

8 nt B cell responses, humoral antibodies, and cell-mediated immunity.

9 akes the link between TLS and a protective B cell-mediated immunity.

10 to the biology of the cell and mechanisms of cell-mediated immunity.

11 g protein tyrosine phosphatases to enhance T cell-mediated immunity.

12 ng cytokines such as TGF-beta1 that regulate cell-mediated immunity.

13 n and binding is crucial for understanding B cell-mediated immunity.

14 infection in the host against the control of cell-mediated immunity.

15 function when operating in conjunction with cell-mediated immunity.

16 are generally focused on the enhancement of cell-mediated immunity.

17 oup of heritable deficiencies of humoral and cell-mediated immunity.

18 melanocytes in feathers appears to be due to cell-mediated immunity.

19 toma tumor were substantially dependent on T cell-mediated immunity.

20 articular focus on molecules associated with cell-mediated immunity.

21 nderlying conditions or diseases that impair cell-mediated immunity.

22 h Ft.LVS::Deltawzy elicited both humoral and cell-mediated immunity.

23 ol of pathogens or tumors usually requires T-cell-mediated immunity.

24 mechanism by which monocytic AML cells evade cell-mediated immunity.

25 optimize vaccines aimed at generating robust cell-mediated immunity.

26 ggests that neurotransmitters can modulate T cell-mediated immunity.

27 ew insights into how CRAC channels control T cell-mediated immunity.

28 ecent studies show that cAMP also promotes T cell-mediated immunity.

29 were independent of hemodynamics and B and T cell-mediated immunity.

30 inflammatory response and efficiently induce cell-mediated immunity.

31 d AIDS, at least in part, through effects on cell-mediated immunity.

32 tic anti-hDectin-1 mAb could elicit CD8(+) T cell-mediated immunity.

33 l and macrophage populations contribute to T cell-mediated immunity.

34 s played by TRAF3 in T cell activation and T cell-mediated immunity.

35 the in vivo functions of CRAC channels for T cell-mediated immunity.

36 important role in initiating or sustaining T cell-mediated immunity.

37 offers new opportunities to regulate CD8+ T cell-mediated immunity.

38 se chimeric vaccines induce both humoral and cell-mediated immunity.

39 auses disease in individuals with suppressed cell-mediated immunity.

40 t are known to stimulate protective CD8(+)-T-cell-mediated immunity.

41 des, and elicit antigen-specific humoral and cell-mediated immunity.

42 and identifies a novel correlate of CD8(+) T cell-mediated immunity.

43 th cytokines are essential in regulating Th1 cell-mediated immunity.

44 designing DENV-specific vaccines that induce cell-mediated immunity.

45 ation of B memory cells, and strong Th1-type cell-mediated immunity.

46 cis-UCA suppresses cell-mediated immunity.

47 or prevent the priming of robust protective cell-mediated immunity.

48 ized by hypergammaglobulinemia and defective cell-mediated immunity.

49 rrelated with classical measures of CD8(+)-T-cell-mediated immunity.

50 stems, of Ag-presentation for stimulation of cell-mediated immunity.

51 cines and therapeutics designed to support T-cell-mediated immunity.

52 gen re-stimulation, suggesting activation of cell-mediated immunity.

53 ty skin test responses, an in vivo marker of cell-mediated immunity.

54 evolutionized our current understanding of T cell-mediated immunity.

55 pathogen containment and in shaping acquired cell-mediated immunity.

56 ion, disease and death can be prevented by T cell-mediated immunity.

57 CD40-CD154 interaction is pivotal for cell-mediated immunity.

58 well-characterized model for studying CD8+ T cell-mediated immunity.

59 nfluenza vaccine that induces antibodies and cell-mediated immunity.

60 crine function and metabolism, but also on T cell-mediated immunity.

61 hat has been implicated as an inhibitor of T cell-mediated immunity.

62 cytosis rates, which leads to suppression of cell-mediated immunity.

63 g to the Ig superfamily and is essential for cell-mediated immunity.

64 ts capable of promoting balanced humoral and cell-mediated immunity.

65 ffectively induces antitumor and antiviral T cell-mediated immunity.

66 ency in the induction of protective CD8(+) T cell-mediated immunity.

67 ction and to evade the direct induction of T cell-mediated immunity.

68 pathway (MHC-I APP), promoting evasion of T cell-mediated immunity.

69 the induction and maintenance of humoral and cell-mediated immunity.

70 arget of interest in efforts to manipulate T cell-mediated immunity.

71 iversity and persistence of vaccine-elicited cell-mediated immunity.

72 Self-non-self discrimination is central to T cell-mediated immunity.

73 f vaccination strategies intended to provoke cell-mediated immunity.

74 rus neutralizing antibodies, as well as weak cell-mediated immunity.

75 ntranasal route and induced both humoral and cell-mediated immunity.

76 T cells is vital for sustaining long-lived T cell-mediated immunity.

77 eneration of T-helper type 1 cells, favoring cell-mediated immunity.

78 n of targets associated with activation of T cell-mediated immunity.

79 rologous protection, indicating a role for T cell-mediated immunity.

80 n of tolerance and foreign Ags to initiate T cell-mediated immunity.

81 terleukin-17A, indicating that PNAG promoted cell-mediated immunity.

82 is a co-inhibitory molecule that modulates T cell-mediated immunity.

83 hysiology), donor-specific antibodies, and T cell-mediated immunity.

84 programming have emerged as modulators of T-cell-mediated immunity.

85 r suppression of humoral alloimmunity as for cell-mediated immunity.

86 key role in generation of HLA peptides for T cell-mediated immunity.

87 gylus brasiliensis is orchestrated by type 2 cell-mediated immunity.

88 tion with cps1-1 elicits long-lasting CD8+ T cell- mediated immunity.

89 nvolved in modifying tumour interaction with cell-mediated immunity; 2p22.3; 7p21.1 AHR, the dioxin r

90 nfection may modulate the establishment of T cell-mediated immunity, adversely affecting long-term pr

91 U treatment in optimally activating a CD4+ T cell-mediated immunity against actinic keratoses and, po

92 The results indicate that cell-mediated immunity against blood-stage malarial para

93 infection, further confirming that CD4(+) T cell-mediated immunity against Brucella is inhibited by

94 s into myeloid cells that activated CD8(+) T cell-mediated immunity against cancer.

95 these have the purpose to promote adaptive T cell-mediated immunity against cancer.

96 ittle is known about the cross-reactivity of cell-mediated immunity against drifted strains in childr

97 tations, identify key molecules required for cell-mediated immunity against EBV, and develop immunoth

98 s in suppressing autologous and allogeneic T cell-mediated immunity against hematologic malignancies.

99 ast cancer (BC) and whether both humoral and cell-mediated immunity against HERV-K can be found in BC

100 e essential for cross-presentation and CD8 T cell-mediated immunity against intracellular pathogens a

101 which pathways are required for memory CD8 T cell-mediated immunity against liver stage Plasmodium in

102 ytolytic pathways that underlie memory CD8 T cell-mediated immunity against liver stage Plasmodium in

103 ex (MHC) class I proteins initiates CD8(+) T cell-mediated immunity against pathogens and cancers.

104 s an extrinsic factor counteracting CD4(+) T-cell-mediated immunity against tumour in old age.

105 mmunity, to evaluate the relationships among cell-mediated immunity, AIDS, and polymorphisms in CCR5,

106 een HIV-1 and HIV-2 is that more efficient T cell-mediated immunity allows for immune-mediated contro

107 d mucosal and systemic SIV-specific CD4(+) T cell mediated immunity and was associated with partial p

108 We studied the relationship between VZV cell-mediated immunity and age after varicella or VZV va

109 Effective B cell-mediated immunity and antibody responses often requ

110 nts or of micronutrients alone on indexes of cell-mediated immunity and antiinflammatory plasma prote

111 tudy, we examined the role of T cell CD98 in cell-mediated immunity and autoimmune disease pathogenes

112 turn-off stage, leading to suppression of T-cell-mediated immunity and autoimmunity.

113 g lung adenocarcinoma development leads to T cell-mediated immunity and disease restraint.

114 dritic cells (DCs), enables antigen-specific cell-mediated immunity and extended antigen presentation

115 e first demonstration of a role for R-Ras in cell-mediated immunity and further expand on the complex

116 These results confirm the role of cell-mediated immunity and highlight the importance of C

117 RP12 as an intrinsic negative regulator of T-cell-mediated immunity and identify altered NF-kappaB re

118 In this study, the cell-mediated immunity and immunoglobulin avidity were e

119 tworks is a significant barrier to effective cell-mediated immunity and immunotherapy.

120 Human CMV infection is controlled by T cell-mediated immunity and in immunosuppressed transplan

121 cells predicted a crucial role for T-bet in cell-mediated immunity and in resistance to many intrace

122 y results in dysfunction of both humoral and cell-mediated immunity and increases the susceptibility

123 oreign antigens to induce strong humoral and cell-mediated immunity and is ideal for a prime-and-boos

124 the ability of B cells to suppress CD4(+) T cell-mediated immunity and modulate CD4(+) T cell effect

125 Cell-mediated immunity and neutralizing antibodies contr

126 s LL-CFA/I, may be harnessed to restrict Th1 cell-mediated immunity and protect against T1D.

127 mplicates NK cells as negative regulators of cell-mediated immunity and suggest that NK cells, like C

128 f pro-TGF-beta1 in vivo, but FURIN's role in cell-mediated immunity and Th polarization has remained

129 pressed FURIN is also a central regulator of cell-mediated immunity and Th1/2 cell balance.

130 ll differentiation and the balance between T cell-mediated immunity and tolerance.

131 ific T cells, contribute to the anatomy of T cell-mediated immunity and tolerance.

132 nimals with paucibacillary disease have high cell-mediated immunity and variable levels of antibody.

133 mmunity, TLR9(-/-) mice showed low levels of cell-mediated immunity and were slightly more resistant

134 SRBC-induced cytokines, reduction in humoral/cell-mediated immunity, and antibody titer was observed.

135 T(FH) cells) are responsible for effective B cell-mediated immunity, and Bcl-6 is a central factor fo

136 immune cross-protection, improve humoral and cell-mediated immunity, and promote antigen dose sparing

137 Dysfunctional cell-mediated immunity appears to be important in the pa

138 Since both humoral immunity and cell-mediated immunity are essential in providing the ho

139 T helper 1 cell responses involved in cell-mediated immunity are key immune parameters that de

140 This finding points to cell-mediated immunity as a relevant pathogenetic mechan

141 nosurveillance, and the induction of T and B cell-mediated immunity, as previously demonstrated using

142 llular and molecular understanding of type-2-cell-mediated immunity, as well as new areas such as the

143 ent of Treg cells specialized to control Th1 cell-mediated immunity at local sites of inflammation.

144 demonstrated to induce enhanced mucosal and cell-mediated immunity better than inactivated vaccines

145 not associated with alterations in CD4(+) T cell-mediated immunity but was preceded by enhanced neut

146 medroxyprogesterone acetate (MPA) can impair cell-mediated immunity, but mechanisms responsible for t

147 candidate adjuvant capable of driving potent cell-mediated immunity, but the mechanism by which it ac

148 glucocorticoids, which can suppress CD8(+) T cell-mediated immunity, but the mechanisms are incomplet

149 CD4(+) T cells promote effective CD8(+) T cell-mediated immunity, but the timing and mechanistic d

150 Boosting T cell-mediated immunity by live attenuated vaccine Mycoba

151 elationship between these factors in shaping cell-mediated immunity by using intravital imaging of CD

152 Cell-mediated immunity can eliminate cancer cells and pr

153 Thus, cell-mediated immunity can function normally despite con

154 sal ganglia and can reactivate due to waning cell-mediated immunity, causing HZ.

155 The CMV-specific cell-mediated immunity (CMI) at baseline and at differen

156 Cell-mediated immunity (CMI) is critically important for

157 s the effect on UVR suppression of cutaneous cell-mediated immunity (CMI) reflected by nickel contact

158 ella-zoster virus (VZV)-specific humoral and cell-mediated immunity (CMI) to herpes zoster (HZ) and p

159 (VZV) vaccine (zoster vaccine), which boosts cell-mediated immunity (CMI) to VZV and decreases the in

160 lue of monitoring pretransplant CMV-specific cell-mediated immunity (CMI) using an interferon-gamma r

161 Cell-mediated immunity (CMI) was measured shortly after

162 tage of CD4 T cells, spontaneous recovery of cell-mediated immunity (CMI) was not seen for TT.

163 (MeV) neutralizing antibody concentrations, cell-mediated immunity (CMI), and immunoglobulin G (IgG)

164 odeficiency virus 1 (HIV-1) relies mainly on cell-mediated immunity (CMI), the determinants of CMI in

165 together with IL28B.rs12979860 genotypes and cell-mediated immunity (CMI).

166 pressed by antibody-mediated immunity and/or cell-mediated immunity (CMI).

167 interleukin 2 (IL-2; markers of VZV-specific cell-mediated immunity [CMI], measured by means of ELISP

168 CMV cell-mediated immunity (CMV-CMI) as determined by a pept

169 CMV cell-mediated immunity (CMV-CMI) can be determined by le

170 of serotype-specific capsular polysaccharide cell-mediated immunity contributes to the clearance of G

171 s required in many instances for effective T cell-mediated immunity, controlling proliferation, and s

172 Although cell-mediated immunity controls intracellular infection,

173 NK cell-mediated immunity correlated with the ordered migra

174 Monitoring of CMV- and VZV-specific cell-mediated immunity could inform immunocompetence and

175 Further, local cell-mediated immunity could not be demonstrated by tetr

176 Cell-mediated immunity critically depends on the localiz

177 Effector-T-cell-mediated immunity depends on the efficient localiza

178 competent memory cells and sustains CD8(+) T-cell-mediated immunity during persistent virus infection

179 It is possible that diminished cell-mediated immunity during pregnancy could increase v

180 nd will help further define the decline in T cell-mediated immunity during the sepsis-induced phase o

181 herefore play a nonredundant role in T and B cell-mediated immunity, especially for protection agains

182 The importance of T cell-mediated immunity for resistance to the disease (cr

183 On the contrary, cell-mediated immunity generated by primary influenza in

184 Suppression of cell-mediated immunity has been proposed as a mechanism

185 s well as for designing vaccines that elicit cell-mediated immunity.IMPORTANCE The high morbidity and

186 es immunosuppressive mechanisms that alter T-cell-mediated immunity in AML.

187 genicity assessed with laboratory markers of cell-mediated immunity in blood and bronchoalveolar lava

188 ignificant SIV-specific mucosal and systemic cell-mediated immunity in both groups, whereas SIV-speci

189 guinea pigs and marmosets and virus-specific cell-mediated immunity in both simian immunodeficiency v

190 An improved understanding of human T cell-mediated immunity in COVID-19 is important for opti

191 olar UV radiation (UVR) suppresses cutaneous cell-mediated immunity in humans.

192 recombinant vaccines for eliciting CD8(+) T cell-mediated immunity in humans; however, prior exposur

193 IV type 1 gag was shown to induce protective cell-mediated immunity in mice against viruses that expr

194 Ctsb(-/-) mice, consistent with a defect in cell-mediated immunity in mice lacking cathepsin L or S.

195 at IL PV-10 therapy induces tumor-specific T cell-mediated immunity in multiple histologic subtypes a

196 nflammatory diseases, the observed role of T-cell-mediated immunity in periodontitis did not readily

197 ed how Gads deficiency would impact CD8(+) T cell-mediated immunity in the context of infection with

198 Consequently, the protective role of cell-mediated immunity in the control of dengue infectio

199 mental model for further dissecting CD4(+) T-cell-mediated immunity in the lung.

200 ocyte hyperplasia, vascular hyperplasia, and cell-mediated immunity in the skin are closely interrela

201 a murine model of immunotherapy to optimize cell-mediated immunity in the skin.

202 1 could play an important role in augmenting cell-mediated immunity in these patients.

203 ul experimental approach to directly study T-cell-mediated immunity in vivo In the rhesus macaque AID

204 haired pointer model produced no evidence of cell-mediated immunity, in contrast to the robust T cell

205 ignaling improves antilisterial defenses and cell-mediated immunity, in general.

206 DS virus infections are rarely controlled by cell-mediated immunity, in part due to viral immune evas

207 ta deletion does not impair overall CD8(+) T cell-mediated immunity, including antiviral immunity, im

208 immunity to fungal pathogens requires intact cell-mediated immunity initiated by DCs, we asked whethe

209 Adaptive, cell-mediated immunity involves the presentation of anti

210 alphabetaT-cell mediated immunity is traditionally characterised by

211 Cell-mediated immunity is a specific target of several m

212 in SCID mice supports the hypothesis that T cell-mediated immunity is critical for host defense agai

213 VZV-specific cell-mediated immunity is critical for the maintenance o

214 Although cell-mediated immunity is critical, increasing evidence

215 T cell-mediated immunity is governed primarily by T cell r

216 Varicella-zoster virus (VZV)-specific cell-mediated immunity is important for protection again

217 Cell-mediated immunity is required for the control of th

218 ed, or where conventional adaptive and/or NK cell-mediated immunity is suppressed.

219 ay a major role in the improvement, and that cell-mediated immunity is the key to understanding E. co

220 Central to CD8(+) T cell-mediated immunity is the recognition of peptide-maj

221 A central paradigm in alphabeta T cell-mediated immunity is the simultaneous co-recognitio

222 Fitness of cell-mediated immunity is thought to depend on TCR diver

223 nses, which can accompany attempts to induce cell-mediated immunity, it is crucial to know which isot

224 that regulate the quality and magnitude of T cell-mediated immunity, known as tolerance checkpoints.

225 Given that cell-mediated immunity may also contribute to parasite c

226 CMV-specific cell-mediated immunity may be able to predict which pati

227 cognized by T lymphocytes, suggesting that T-cell-mediated immunity may be harnessed for the immunoth

228 Exposed birds had significantly lower cell-mediated immunity (measured using phytohaemagglutin

229 Due to functionally distinct cell-mediated immunity, newborns and infants are highly

230 tionally focused on producing humoral and/or cell-mediated immunity, often against the viral surface

231 eceptors, less is known about the effects of cell-mediated immunity on Beclin 1 and ULK1, key regulat

232 use of morbidity in patients with defects in cell-mediated immunity or saliva production.

233 e response and no effect on other markers of cell-mediated immunity or systemic and gut inflammation.

234 Supported by a mixed Th1/Th2 cell-mediated immunity, P27A induced a marked specific a

235 microMT mice as recipients, we found that T-cell-mediated immunity plays a secondary but still signi

236 Cell-mediated immunity plays an important role in immuni

237 disease occurs in the context of suppressed cell-mediated immunity post-transplantation, humoral imm

238 versus 2D (M0,12); neutralizing antibodies; cell-mediated immunity; reactogenicity; and safety.

239 cing lifelong protective B-cell responses, T-cell-mediated immunity remains challenging.

240 KG2D-driven regulation of CD4+ T helper (Th) cell-mediated immunity remains unclear.

241 However, how DRD3 signaling affects T cell-mediated immunity remains unknown.

242 CMV-specific cell-mediated immunity represents a relevant marker in a

243 Protective CD8(+) T cell-mediated immunity requires a massive expansion in c

244 T cell-mediated immunity requires T cell receptor (TCR) cr

245 virus (HCV) infection decreases humoral and cell-mediated immunity responses to hepatitis B vaccinat

246 Purine analogues and alemtuzumab alter cell-mediated immunity, resulting in opportunistic viral

247 e major new information involves the role of cell-mediated immunity, specifically T-helper 17 cells a

248 Cell-mediated immunity stems from the proliferation of n

249 Defects in cell-mediated immunity, such as thymic atrophy, impaired

250 CD4 T cells are crucial for enhancing B cell-mediated immunity, supporting the induction of high

251 that can coordinately induce multi-epitope T cell-mediated immunity, T helper functions, and immunolo

252 s is an emerging approach to elicit CD8(+) T cell-mediated immunity targeting pathogens and tumor Ags

253 s with similar or even higher PRN titers and cell-mediated immunity than adult mice.

254 , pleiomorphic cells capable of modulating T cell-mediated immunity, that heretofore have been studie

255 Thus, during transition to adaptive T cell-mediated immunity, the ILC2 and T cell crosstalk co

256 ith WISP1 as a paracrine inhibitor of type 1 cell-mediated immunity through inhibiting IL12 signaling

257 (TNFR) superfamily, has a pivotal role in B-cell-mediated immunity through various effector pathways

258 ncludes a combination of innate, humoral and cell-mediated immunity) through mucosal vaccination migh

259 s, whereas MyD88(-/-) mice completely lacked cell-mediated immunity, TLR9(-/-) mice showed low levels

260 model to investigate the role of humoral and cell-mediated immunities to influenza and their effect o

261 The induction of cell-mediated immunity to C. albicans is of critical imp

262 The induction of cell-mediated immunity to C. albicans is one of the main

263 nd HSP70 play a key role in the induction of cell-mediated immunity to carcinogenic polyaromatic hydr

264 We tested the role of cell-mediated immunity to collagen type V [col(V)] in th

265 n of the immune system, allowing more potent cell-mediated immunity to develop in dangerous environme

266 T cell-mediated immunity to infection is due to the prolif

267 s to a T-dependent Ag, as well as impaired T cell-mediated immunity to infection with Listeria monocy

268 t where the push for vaccines that exploit T cell-mediated immunity to malaria has made it imperative

269 Thus, optimal NK cell-mediated immunity to MCMV depends on Ly49H signalin

270 T cell-mediated immunity to microbes and to cancer can be

271 estions remain regarding the significance of cell-mediated immunity to MSP1 in conferring protection

272 EAE is induced by stimulating T-cell-mediated immunity to myelin antigens.

273 eningitidis, there is an absence of adaptive cell-mediated immunity to N. lactamica during the peak a

274 was recently reported to be important in Th2 cell-mediated immunity to parasitic infection.

275 ytotoxic T cells and natural killer cells of cell-mediated immunity to provide tumor (B16-ova-Melanom

276 eserved the T-cell compartment and sustained cell-mediated immunity to SIV.

277 ity responses, a powerful in vivo measure of cell-mediated immunity, to evaluate the relationships am

278 e environment became further resistant to NK cell-mediated immunity upon cancer cell infiltration.

279 ated the potential function of galectin-3 in cell-mediated immunity using peripheral blood monocytes.

280 This cell-mediated immunity vaccine did not prevent HIV-1 inf

281 ep Study directly assessed the efficacy of a cell-mediated immunity vaccine to protect against HIV-1

282 lecularly concoct adjuvants to elicit potent cell-mediated immunity via activation of innate and adap

283 ears thereafter were tested for VZV-specific cell-mediated immunity (VZV-CMI) by gamma-interferon ELI

284 Varicella-zoster virus (VZV) T-cell-mediated immunity (VZV-CMI) in older persons preven

285 We compared varicella-zoster virus cell-mediated immunity (VZV-CMI) of adults >=70 years wh

286 ine in varicella-zoster virus (VZV)-specific cell-mediated immunity (VZV-CMI).

287 With a decline in VZV-specific cell-mediated immunity, VZV reactivates from ganglia and

288 mechanisms by which C. gattii might subvert cell-mediated immunity, we found that C. gattii failed t

289 nd few studies have included measurements of cell-mediated immunity.We assessed the effects of diets

290 Robust systemic and mucosal antibody- and T cell-mediated immunities were induced against both prote

291 e-specific and cross-reactive antibodies and cell-mediated immunity were measured.

292 erent roles: T cells contribute to and drive cell-mediated immunity, whereas B cells secrete Abs.

293 Adult frogs possess efficient conventional T cell-mediated immunity, whereas tadpoles predominantly r

294 Although presumed to induce T cell-mediated immunity, whether tumor elimination depend

295 3 and K5 suppress both cytokine-mediated and cell-mediated immunity, which ensures efficient viral av

296 ased resistance of Mig-deficient tumors to T cell-mediated immunity, which promotes the accelerated g

297 irus after the normal decline in humoral and cell-mediated immunity with time.

298 hy systemic immunization routes induce local cell-mediated immunity within the intestine and indicate

299 lls to downregulate MHC class I, to escape T-cell-mediated immunity without inducing susceptibility t

300 ns shape the T-cell repertoire, as well as T-cell-mediated immunity; yet, the mechanisms that underli