ライフサイエンスコーパス: characterization

1 tion, which has ramifications for riboswitch characterization.

2 up of restriction endonucleases for detailed characterization.

3 atography (RPLC) coupled with MS for protein characterization.

4 particle size distribution and morphological characterization.

5 ss has been made towards its high-resolution characterization.

6 molecular dynamics simulations and enzymatic characterization.

7 echnique that can provide a complete surface characterization.

8 extensive pre-clinical in vitro and in vivo characterization.

9 hallenges to effective nanoscale crystalline characterization.

10 ds, including structure-based and functional characterization.

11 logically relevant membranes for biophysical characterization.

12 acromolecules for structural and biophysical characterization.

13 required for improving their pharmacological characterization.

14 smission electron microscopy, and electrical characterization.

15 Such model is useful for plant cell characterization allowing a single set of parameters ove

16 iety of chemical, structural, and electrical characterizations along with multidomain finite-element

17 Risk characterization analysis showed that although in vitro

18 Then, the realization, characterization and biomedical application of natural a

19 Chemical characterization and CAP phytoconstituent profile was ob

20 Extended X-ray absorption fine structure characterization and density functional theory calculati

21 The structural characterization and electrochemical sensor features of

22 Functional characterization and fine-mapping of that locus reveal a

23 While their characterization and quantification by (29) Si NMR spect

24 diversity due to lack of efficient germplasm characterization and structure.

25 eference genomes are required for functional characterization and taxonomic assignment of the human g

26 The synthesis characterization and theoretical analysis of these compo

27 Characterization and understanding of their atomic struc

28 ets and complements other tools for complete characterization and visualization of the genomic and tr

29 toantibodies, carried out related functional characterization, and compared results with those of 60

30 otein engineering, surface plasmon resonance characterization, and molecular dynamics (MD) simulation

31 in order to facilitate efficient isolation, characterization, and quantitation of drug substances in

32 we describe the identification, maturation, characterization, and utilization of a CDP that binds to

33 e relevant mathematical parameters for their characterization are available; however, such parameters

34 ns, time of growth, specificity of microbial characterization) are barriers to drawing robust conclus

35 low detailed morphological and physiological characterization as well as genetic manipulation.

36 olution for variant discovery and functional characterization, as well as disease modeling and in viv

37 ality for further biochemical and structural characterization, as well as for use in consumer product

38 ing of nanoparticle separation with chemical characterization bears potential to close this gap.

39 al pyrite was evidenced, as deduced from its characterization before and after use.

40 Structural characterization by CryoEM reveals a lipid-induced stabi

41 In this study, structural characterization by electron-induced dissociation (EID)

42 ble at low temperatures, thus permitting its characterization by NMR, EPR, X-ray, and HRMS.

43 obe protein systems that are not amenable to characterization by x-ray crystallography, NMR or EM.

44 the isolation of these clusters and complete characterization by X-ray, TGA, UV-vis, and ICP studies.

45 Characterizations by biochemical, biophysical, and rever

46 We demonstrate that holographic particle characterization can directly detect binding of proteins

47 rs leading to more complete functional group characterization compared to CAD.

48 pitation with deep sequencing and functional characterization conducted in human induced pluripotent

49 Not only is this characterization contentious, it appears to be falsified

50 opportunities in geophysical exploration and characterization could arise.

51 from the development of a suite of materials characterization, damage quantification, and therapeutic

52 become a powerful tool for glycan structural characterization due to its ability to separate isomers

53 many directions, including membrane protein characterization, endocytosis, secretion, protein foldin

54 a in four main criteria categories (particle characterization, experimental design, applicability in

55 is study provides a framework for developing characterization factors for functional diversity as aff

56 nd temporal resolution, in situ and operando characterization, first-principles simulation, high thro

57 This limits reliable and facile characterization; for example, when using common substra

58 In-depth structural characterization from a suite of biophysical methods, in

59 By comprehensive characterizations from atomic-scale structures to large-

60 Their anatomical-functional characterization has been impeded by the inability to se

61 molecule level, a benchmark for bulk sample characterization, has remained elusive.

62 This structural and biochemical characterization helps to rationalize the preference of

63 NMR-based molecular-level characterization identified the docking site on PrP(C) t

64 of prediction tools toward protein disorder characterization in health and disease.

65 tem that enables the high-throughput protein characterization in insect cells by taking advantage of

66 anning electron microscopy for morphological characterization indicated that the microcapsules so obt

67 Thermodynamic characterization is crucial for understanding molecular

68 Heterogeneity characterization is crucial to define the quality of end

69 The characterization is in terms of two notions of the effec

70 disulfide bonds-making it attractive for mAb characterization-it can be less effective for precursors

71 ter purification and mass spectrometry-based characterization, its oral bioavailability was measured

72 Here we performed a comprehensive behavioral characterization of 16p11.2 duplication mice (16p11.2(dp

73 Furthermore, characterization of 2 using combined spectroscopic and c

74 In this work, the optical characterization of 2D materials is used as a case study

75 Here, we provide a complete genomic characterization of 55 representative Latin American VRE

76 nding the human genome is the relative under-characterization of 90% of protein coding regions.

77 Electrochemical characterization of [Co(13)C(2)(CO)(24)](4-) in the pres

78 Herein, we present the synthesis and characterization of a macrocyclic polyamide cage that in

79 We report the synthesis and characterization of a monochloride-functionalized polyox

80 emical synthesis and preliminary biochemical characterization of a new oligonucleotide analogue calle

81 Here we report the discovery and characterization of a previously undescribed copper cent

82 The synthesis and characterization of a series of light-driven third-gener

83 t here the design, synthesis, and biological characterization of a series of novel N-arylsufonamides

84 Herein we report the design, synthesis, and characterization of a ternary 0D organic metal halide hy

85 (2) A week-by-week study for the characterization of AAA development with imaging after 1

86 Here, we report on the characterization of acyl-activating enzymes (AAEs) that

87 Here we report the isolation and characterization of all-silicon 1,3-cyclobutanediyls as

88 In vitro and in vivo characterization of AMT-101 showed it to efficiently cro

89 olation of key intermediates, the structural characterization of an iron-metallacycle, and kinetic an

90 Herein, we report on the detailed structural characterization of atmospherically relevant isoprene-de

91 tom-up synthesis have enabled the design and characterization of atomically precise GNRs, but strateg

92 The reproducible generation and characterization of attosecond waveforms has been demons

93 By providing structural characterization of authentic C-H functionalization inte

94 We performed detailed characterization of B cell responses through high-dimens

95 mprovement), and high-throughput (>96 wells) characterization of bacterial electrogenicity from a sin

96 empirical studies devoted to the data-driven characterization of behavioral changes induced by infect

97 a significant challenge to the discovery and characterization of biologically relevant GBP-GSL intera

98 esults present a comprehensive phytochemical characterization of black onions, highlighting the signi

99 Reducing unnecessary biopsies and rapid characterization of breast microcalcifications are unmet

100 Additional characterization of bRSV IBs indicated that although the

101 Molecular characterization of BsAbs' epitopes not only allows for

102 compounds) are extremely useful for in vivo characterization of central nervous system drug candidat

103 CT angiography is highly sensitive in the characterization of cerebral AVMs measuring less than 3c

104 erformed the first single-cell transcriptome characterization of CF sputum.Objectives: To define the

105 Characterization of circadian systems at the organism le

106 ed here make them a valuable new tool in the characterization of complex eukaryotic carbohydrate-degr

107 e mass spectrometry (MS) for the biophysical characterization of complex formation of a BsAb with two

108 signals and provide a means for quantitative characterization of complex spatial patterns in developm

109 data provide a more fine-grained and nuanced characterization of cortical auditory processing in the

110 rein, the synthesis, isolation, and physical characterization of Cp(2)Ti(kappa(2)-(t)BuNCN(t)Bu) (3)

111 c expedition to conduct the first systematic characterization of deep-sea benthic invertebrate commun

112 Characterization of defined mutations in vitro identifie

113 Our characterization of Diachasmimorpha longicaudata entomop

114 chemical impedance spectroscopy (EIS) in the characterization of different beverages, namely ground c

115 om a 'bottom-up' approach including: (i) the characterization of different brain circuits to understa

116 in both diagnostic strategies and functional characterization of disease mechanisms.

117 Here, we undertook a systematic characterization of diverse rare and private spliceosoma

118 y from the biological point of view with the characterization of dormancy through the description of

119 f middle-level CIU was evaluated through the characterization of eculizumab, a hybrid therapeutic IgG

120 Initial characterization of EMVs derived from idiopathic patient

121 Characterization of enhancer loci has identified the mol

122 Detailed characterization of erythrocyte and macrophage subpopula

123 Accurate biological characterization of exosomes is an important step toward

124 In particular, we describe the characterization of folding energy landscapes at high re

125 lysis with Gag-ESCRT binding studies and the characterization of Gag-plasma membrane binding and Gag

126 This characterization of Galapagos deep-sea benthic invertebr

127 Characterization of GFP-BAF accumulation at nuclear memb

128 arkedly improved the comprehensive proteomic characterization of global proteome and protein post-tra

129 s suitable for TMT-based intact glycopeptide characterization of glycoproteins.

130 hem are typically examined leading to a weak characterization of habitat connectivity.

131 An in silico screen and characterization of HCT 116 cells lacking p300 suggested

132 )MS) method for charge detection enables the characterization of highly complicated mixtures of prote

133 ide the so-far most comprehensive functional characterization of human tRNAs with intricate roles in

134 ptions.METHODSWe performed a flow cytometric characterization of immune cell subsets from 30 patients

135 Characterization of immune responses is currently hamper

136 enabling quantitative and dynamic phenotypic characterization of individual cells and, in particular,

137 elerate the comprehensive classification and characterization of individual somatosensory neuronal su

138 umor suppressor genes and to obtain a deeper characterization of known cancer genes.

139 ity, effect of bentonite and electrophoresis characterization of laccase in the presence of different

140 However, structural-mechanical characterization of lamin filaments assembled in situ re

141 Here we provide the first comprehensive characterization of magnocellular and parvocellular oxyt

142 studied, while the functional and mechanical characterization of major PTMs is well documented in sev

143 Multi-scale characterization of mannan hydrolysate was done using FT

144 However, better characterization of material-specific NH(3) emissions fr

145 Further characterization of metabolic changes after INSTI initia

146 tion composition, manufacturing process, and characterization of microparticle systems.

147 Characterization of microstructure, chemistry and functi

148 Since the characterization of mRNA in 1961, our understanding of t

149 Studies have reported the characterization of N-glycans in rodent brains, but ther

150 properties of engineered viruses thus enable characterization of neuronal function at unprecedented r

151 fluidic technology is an attractive tool for characterization of neutrophil migration.

152 rein, we describe the design, synthesis, and characterization of new dual inhibitors of ULK1 and ULK2

153 sis and subsequent accelerated discovery and characterization of new natural products.

154 Its modular design also enables characterization of non-tumor hemodynamics (e.g. brain),

155 field of proteomics, allowing a more facile characterization of novel gene products and subcellular

156 This method forms a key step of de novo characterization of nucleotide modifications, shedding l

157 rly studies highlighted by the isolation and characterization of numerous vaccinia virus enzymes, det

158 drowsy driving in nurses requires a thorough characterization of nurse's perceptions of drowsy drivin

159 on of Orbitrap for real-time, near-molecular characterization of OAs.

160 Functional characterization of OFF-RGC terminals in tectum revealed

161 applied for a comprehensive polar lipidomic characterization of olive oils.

162 A detailed methodology for the characterization of organic photodiodes based on polymer

163 applicable to the kinetic stabilization and characterization of other weak functional group interact

164 We perform a detailed characterization of our engineered ENHANCE system with v

165 Characterization of our NHP model of behavioral inhibiti

166 We report the synthesis and characterization of P-phenyl modified phosphorus- and ni

167 The developed method was applied for the characterization of PCs of wines, bunch stems and grape

168 Multi-response optimization and characterization of physical, chemical, and techno-funct

169 t here the positional cloning and functional characterization of Pm41, a powdery mildew resistance ge

170 This theoretical work addresses the characterization of polymer-coated nanoparticles via the

171 tion, rapid inhibitor screening, and further characterization of positive hits (that is, IC(50) and K

172 treatments are largely based on the genetic characterization of primary tumors and are ineffective f

173 The characterization of prokaryotic serine/threonine protein

174 I has the potential to improve diagnosis and characterization of prostate cancer (PCa), but validatio

175 Characterization of protein primary sequence, however, h

176 The signals enable quantitative characterization of protein-ligand interactions.

177 report the map-based cloning and functional characterization of qFIRM SKIN 1 (qFIS1), a major quanti

178 generally necessary for in vitro and in vivo characterization of radioligands(2), yet there exist few

179 so report spectroscopic and crystallographic characterization of rare Cu-hemiacetalate and Cu-hemiami

180 Nevertheless, this study demonstrates that characterization of S. aureus CC and virulence genes hel

181 We also report the characterization of several previously unknown halophili

182 strategy for genome-wide identification and characterization of silencer elements.

183 toire involved in disease resistance and the characterization of Sm1(6), a gene associated with insec

184 single proteins is crucial for comprehensive characterization of some important glycoproteins, such a

185 These results yield the most comprehensive characterization of specific and ubiquitous small RNAs i

186 tural diversity of carbohydrates hampers the characterization of specific glycan determinants.

187 In this study, we provide a quantitative characterization of spontaneous polarity site movement a

188 Here we describe the discovery and characterization of ST-2262, a Na(V)1.7 inhibitor that b

189 Not only does this process provide characterization of structurally complex molecules, it w

190 ease agents may be debatable, the functional characterization of such antibodies represents a powerfu

191 Characterization of such transient weak interactions at

192 interactions hampers the identification and characterization of T cell-activating epitopes.

193 Here, we report the identification and characterization of the amidobenzimidazoles (AB) protein

194 ological, structural, electrical and optical characterization of the beta-Ga(2)O(3) nanowires includi

195 quate knowledge of the risks necessitate the characterization of the billions of nanoparticles contai

196 Further characterization of the biologically active 6C protein d

197 In addition, by providing a two-dimensional characterization of the CFTR protein, it could better in

198 ocks inflammation in vivo Identification and characterization of the chemokine-binding interface of e

199 Characterization of the color of the plastic is often in

200 Although challenging, characterization of the conformational ensembles of IDPs

201 schizophrenia, a C4 inhibitor and structural characterization of the convertase formed by C4b is lack

202 However, experimental characterization of the diversity of transition paths is

203 (SLIM IMS-MS) for the rapid and simultaneous characterization of the drug load profile (i.e., stoichi

204 he 2D-LC-CRMS strategy enables the sensitive characterization of the entire impurity profile of the h

205 Characterization of the events that underlie entry and w

206 Further characterization of the extracellular matrix showed stro

207 this work, we introduce the fabrication and characterization of the first ever documented Thermal AN

208 We report the synthesis and characterization of the first plutonium metal-organic fr

209 he synthesis, structure, and physicochemical characterization of the first three examples of neutral

210 (1)H NMR, FTIR, and GC/MS characterization of the fluids indicated that they are m

211 conformation landscape whose study requires characterization of the ground and excited conformation

212 Characterization of the higher-order structures in idurs

213 However, despite extensive characterization of the HSC state in the adult bone marr

214 ere, the holistic engineering and systematic characterization of the impact of molecular and ionic fi

215 the lipid-binding domain allowed a detailed characterization of the individual kinetic steps of huma

216 Focusing on the biophysical characterization of the knot region by NMR spectroscopy,

217 Characterization of the LEC secretome identified the ext

218 Furthermore, we show an extensive chemical characterization of the LnPOM species present in the sol

219 ollected at baseline, crossover and exit for characterization of the microbiota and measurement of cy

220 This characterization of the mobility of individual photosynt

221 is still in its infancy, requiring in-depth characterization of the molecular landscape shaping thes

222 workflow for the purification and systematic characterization of the molecular structure of cutin.

223 s using the ZipChip platform for comparative characterization of the monoclonal antibody Cetuximab.

224 ions highlight the importance in the further characterization of the neuropathology of DMD.

225 l resources and tools for further functional characterization of the niche in the future.

226 We provide the first molecular characterization of the PM-PER tether and show it anchor

227 As such, interest in the identification and characterization of the previously ignored 'dark proteom

228 Characterization of the products by multimode electron t

229 xtracted HRMS signals of MACs yield a better characterization of the studied groups compared to resul

230 discriminant analysis for the validation and characterization of the surface chemistry.

231 Characterization of the system shows the speed of partic

232 Characterization of the turnover chemistry of Pgp3 revea

233 (FT-ICR MS) enables extensive compositional characterization of the virgin asphalt binder, irradiate

234 ion of novel ubiquitin and UBL sites and the characterization of the writers, erasers, and readers, t

235 allenges for the comprehensive bioanalytical characterization of their pharmacokinetics (PK) and cata

236 ssessment of MeONP inflammatory potential by characterization of their physicochemical properties.

237 Innovatively, LHM allowed the characterization of these effects at a molecular level.

238 numerous questions regarding the biological characterization of these human groups, especially regar

239 Characterization of these materials is challenging becau

240 tials of VCPs, implying the need for further characterization of these nontraditional emissions.

241 The characterization of these polymers by mass spectrometry

242 DCLK1-IN-1, developed to aid the functional characterization of this important kinase.

243 subsequent steps and allow interception and characterization of this long hypothesized intermediate.

244 Further characterization of this mechanism may provide informati

245 Characterization of this phage validated the predicted p

246 The characterization of three PTC mutations, E60X-, G542X- a

247 rse-transcription step, preventing effective characterization of transcriptome complexity.

248 Here, in vivo characterization of tumor-associated USP22 upregulation

249 y greatly facilitate the extensive molecular characterization of tumors and promote precision medicin

250 e of breast cancer genomics with the genomic characterization of tumors offering exceptional opportun

251 techniques now enable more precise molecular characterization of tumors, multigenetic tumor profiling

252 Here we report a detailed characterization of two late-acting Fe-S cluster-carrier

253 We report the isolation and characterization of two ultrapotent SARS-CoV-2 human neu

254 Here, we describe the generation and characterization of typhoid toxin-neutralizing human mon

255 rt the discovery and the petrologic-isotopic characterization of UH154-11, a ferroan trachybasalt fra

256 ially powerful and specific approach for the characterization of unknown glycans.

257 ress other identified gaps in the analytical characterization of various classes of NEPs.

258 Sequence-based characterization of virulence and antibiotic resistance

259 ks leads to novel forms of correlations, the characterization of which is, however, challenging.

260 like previous manual or semi-manual methods, characterization of z-line architecture using the metric

261 To avoid such erroneous characterization of ZrC(x) thermophysical properties in

262 Here, we report the characterizations of Mfsd7c-KO mice and compare these ch

263 s, and show that it produces highly accurate characterizations of quantum processes.

264 ns imposed by interfacial effects-as seen in characterizations of the charge generation and transfer

265 e to the formation of seed oil, and previous characterizations of various DGAT2 enzymes indicate that

266 wn) using a rapid split fluorescent reporter characterization platform, and establish a library of 15

267 atopoietic cells has made in vivo functional characterization possible.

268 This characterization provides insight into differences in th

269 : perturbation, visualization, substitution, characterization, reconstitution, and simulation.

270 Further phenotypic characterization revealed heterogeneous neutrophil popul

271 Kinetic characterization revealed that the MpBgl3 was highly tol

272 Overall, these characterizations revealed the architecture of the SARS-

273 Functional characterization showed that MTCH2 and MTCH2x were local

274 Structural and optical characterization showed that the inorganic lattice is no

275 Together with electrophysiological characterization, structures of TRPV3 in a lipid membran

276 ared with toxicological thresholds in a risk characterization study.

277 ed procedure, and the utility of the various characterization techniques is discussed, emphasizing th

278 ed and spread rapidly after the retooling of characterization techniques that happened in the last tw

279 Herein, we apply recently developed 2D characterization techniques to nanoparticles using atmos

280 from the viewpoint of materials science and characterization techniques.

281 We introduce a topological characterization, the hub-set-orientation prevalence of

282 In combination with functional characterization, this work elucidates the previously un

283 Mechanistic characterization through time-of-addition studies, trans

284 Mechanistic characterization through viral RNA profiling and in vitr

285 lectrochromic devices often need appropriate characterization to establish the real working mechanism

286 )RR, and emphasize the importance of in situ characterization to understand the surface structure and

287 izations of Mfsd7c-KO mice and compare these characterizations to phenotypic findings in humans with

288 e pharmaceutical sector requires new protein characterization tools that are fast, applicable in situ

289 Automated tissue identification and characterization using a single atlas segmentation perfo

290 Extensive characterization validates the robustness and nonperturb

291 ere, we describe fusion construct design and characterization (variable timing), proteomic sample pre

292 er monitoring) and Doppler-echocardiographic characterization, was identified.

293 Along with spectroscopic characterization, we demonstrate that the probe improves

294 discovery and subsequent structure-function characterization, we present simple peptides that bind a

295 After characterization, we quantified 11 candidate miRNAs asso

296 ny plant species, but its identification and characterization were not possible until a reference gen

297 Genomic diversity and characterization were performed by whole genome sequenci

298 Triangulating this cellular characterization with cleavage signatures of 178 proteas

299 , which can only be understood by structural characterization with high spatial 3D resolution.

300 that can be tailored to balance the depth of characterization with speed and throughput.