ライフサイエンスコーパス: chelating

1 The metal chelating abilities (34.92-57.38mgEDTA/g) and in vitro a

2 ical scavenging, reduction of metal ions and chelating abilities against ferrous ions.

3 ) radical scavenging activities, ferrous ion chelating abilities and reducing power results showed th

4 All these polyanils showed good chelating abilities toward trivalent boron fragments suc

5 al scavenging capacity (50.18-86.79%), metal chelating ability (0.21-8.15%), ferric ion reducing powe

6 assay (67.66%), ABTS assay (78.81%), Fe(2+) chelating ability (51.20%), hydroxyl assay (60.95%) and

7 ical, ABTS radical, hydroxyl radical, Fe(2+) chelating ability and reducing power.

8 lacking the sch gene cluster lost their iron-chelating ability as quantified by the chrome azurol S (

9 DPPH, hydroxyl and peroxyl; and Ferrous Ion-chelating Ability Assay).

10 polyethyeleneimine (PEI), which has a strong chelating ability for Cu(2+) ions.

11 ty measurements, i.e. the reducing power and chelating ability measurements, for appropriate comparis

12 The better chelating ability of GA than CA was supported by the hig

13 es smaller than 5kDa were evaluated for iron chelating ability through measurements of iron solubilit

14 gands, which are well known for their strong chelating ability to different metal ions.

15 Cu(2+)-chelating ability was significantly correlated to FRAP,

16 0.05) correlations were obtained with Fe(2+)-chelating ability.

17 sessing a druglike chemotype and modest iron-chelating ability.

18 ckness, and the results demonstrate that the chelating action and dispersing effect of EDTA is critic

19 These results suggest that metal-chelating active packaging coatings may present a new te

20 ylhydrazyl radical inhibiting and Fe(2+) ion chelating activities (IC50 25.05 and 350.7muM, respectiv

21 en quenching, reducing power and ferrous ion-chelating activities of CS were also pronounced.

22 , 3.6 and 0.035 for scavenging, reducing and chelating activities, respectively.

23 ing activities (p<0.05), but limited ferrous chelating activities.

24 radical scavenging, reducing ferric ions and chelating activities.

25 razyl antioxidant activities and ferrous ion chelating activities.

26 hing inhibition (91.75 +/- 0.22%) and Cu(2+)-chelating activity (74.53 +/- 0.58%).

27 activity (IC50=39.33 +/- 3.2 mug/mL), metal chelating activity (IC50=56.51 +/- 3.6 mug/mL) and inhib

28 cavenging activity, reducing power, Fe(2)(+) chelating activity and inhibition of lipid oxidation in

29 y good radical scavenging activity, Fe(2)(+) chelating activity and reducing power while the fraction

30 were analyzed for antioxidant activity, Iron chelating activity and total phenolic content.

31 In contrast, reducing power and iron chelating activity seemed to be caused by peptides.

32 s showed significantly (p 0.05) higher metal chelating activity than other fractions.

33 hocyanin content and 16.6-43.2% higher metal chelating activity than the cultivars grown in plains (9

34 All sub-fractions showed high Fe(2+) chelating activity.

35 scavenging activity, reducing power and iron chelating activity.

36 assay showed 71.3% inhibition and 65.8% Iron chelating activity.

37 eds are good source of antioxidants and Iron chelating activity.

38 g antioxidant power (FRAP) and iron (Fe(2+)) chelating activity.

39 WF possessed moderate copper chelating activity.

40 phenoloxidase inhibitory activity and copper chelating activity.

41 The test area was then burnished with a chelating agent (EDTA) for 30 seconds and images again m

42 at trace level using 8-hydroxyquinoline as a chelating agent and lanthanum(III) as a carrier element

43 optimization with regard to the radionuclide-chelating agent and the linker moiety between chelator a

44 Deferoxamine (DFO), an iron-chelating agent clinically used to treat iron toxicity,

45 Treating infant formulas with the chelating agent diethylene triamine pentaacetic acid (DT

46 A NOTA ligand is the chelating agent for the (68)Ga, and two related opioid p

47 been developed using the incorporation of a chelating agent in a common organic solvent, dimethyl su

48 or precursor cadmium complex that works as a chelating agent in order to increase optical and electri

49 suggests the importance of the alkali metal chelating agent in the reversibility of dinitrogen bindi

50 based on the cationic dye Pyronin Y (PY) and chelating agent meso-2,3-dimercaptosuccinic acid (DMSA)

51 uman growth hormone, rhGH) modified with the chelating agent S-2-(4-isothiocyanatobenzyl)-1,4,7-triaz

52 events produced by the translocation of the chelating agent through an alpha-hemolysin pore in the a

53 Da as an antimicrobial extrafibrillar dentin-chelating agent to enhance bond durability.

54 en verified as calculus and the ability of a chelating agent to remove calculus has not been proven.

55 Furthermore, the amount of the chelating agent used also affects the phase purity and e

56 stability increased to a great extent when a chelating agent was added.

57 ing 4-nitro-o-phenylenediamine (4-NOPD) as a chelating agent was developed for mercury speciation in

58 By employing a polyhistidine molecule as a chelating agent, and based on the different signatures o

59 l clinical setting, patient population, iron chelating agent, and dosing regimen.

60 Ethylene diamine tetraacetic acid (EDTA), a chelating agent, can resorb mineral deposits, but the sy

61 EDTA, a powerful chelating agent, did not have any significant effect on

62 Using EDTA as chelating agent, we observed an increased binding to AcB

63 ma mandarin fruits was extracted to obtain a chelating agent-soluble pectin fraction (ChSS), a dilute

64 d to determine if calculus is removed with a chelating agent.

65 e, a target interaction element, and a metal chelating agent.

66 with deferoxamine, a clinically useful iron-chelating agent.

67 of calculus are reduced or eliminated with a chelating agent.

68 les in a process that could be affected by a chelating agent.

69 calculus, which are removed by the use of a chelating agent.

70 n the perspective of developing bifunctional chelating agents (BCAs), this new synthetic strategy off

71 Chelating agents (EDTA formulations) reduced E. coli CFU

72 ubstantially surpassing conventional Gd(III) chelating agents (r1 approximately 3 mM(-1)s(-1) at 4.7

73 polymerisation (RDRP), with a range of metal-chelating agents and monomers that can be used under amb

74 e, we place a polymer film blended with lead-chelating agents between the metal electrode and a stand

75 ical "braking" system was achieved by adding chelating agents capable of sequestering the metal ion e

76 Chelating agents in children were not significantly asso

77 (IV) with Gallocyanin (GC(+)) and glycine as chelating agents in the mixed surfactant media, Polyethy

78 Treatment of DHHC3 with chelating agents in vitro replicated both the specific s

79 Several strategies such as the inclusion of chelating agents or highly branched polymers may overcom

80 this system being less influenced by pH and chelating agents present in the extracts.

81 Siderophores are natural metal chelating agents that strongly control the biogeochemica

82 Currently, chelating agents used in (68)Ga radiopharmaceuticals do

83 to the disease itself, iron overload or the chelating agents used.

84 ing Ac complexes that contain highly complex chelating agents using small quantities (mug) of (227)Ac

85 Rather than using the chelating agents which are commonly used in CPE to form

86 application of UV-Fenton processes with two chelating agents, nitrilotriacetic acid (NTA) and [S,S]-

87 cessible overview of the field of radiometal chelating agents.

88 ic acid, citrate, into the soil rhizosphere, chelating Al(3+) ions and thereby imparting Al-resistanc

89 ve in both genotypes, most likely because of chelating amino acids present in the murine nutrient sol

90 s how the new and rapidly expanding class of chelating ancillary ligands bearing 2,2'-bipyridyl, 1,10

91 nsity lipoprotein (LDL) catalysed by copper (chelating and chain-breaking activity).

92 we show how harnessing the redox-switchable chelating and donating properties of an ortho-substitute

93 the rainy season presented the higher Fe(2+) chelating and Ferric reducing activities.

94 Chelating and free radicals scavenging activities of ext

95 on parameters were useful for distinguishing chelating and nonchelating monomers and determining the

96 ioxidant activity (DPPH, ABTS, CUPRAC, FRAP, chelating and phosphomolybdenum assay) and enzyme-inhibi

97 ers using three model systems (DPPH, ferrous chelating and reducing power).

98 Both the chelating and the indicating nanospheres showed good sel

99 (both protic and aprotic) are bifurcated and chelating, and unlike many molecular liquids a significa

100 ate that holomycin is an intracellular metal-chelating antibiotic that inhibits a subset of metalloen

101 L5a should be considered a new class of zinc-chelating anticancer agents that deserves further develo

102 e installation of other donors as the fourth chelating arm, while avoiding the formation of stereoiso

103 symmetrical N-distribution of the functional chelating arms.

104 lfur, but also with a neighboring Rh and the chelating aryl carbon of the pincer framework.

105 talyst based on NiXantphos, a deprotonatable chelating aryldiphosphine ligand, to oxidatively add una

106 ity due to the required distance between the chelating atom in the attached directing group and the t

107 These styrenes are precursors to the chelating benzylidene moiety in a proposed series of nov

108 ied and typically relies on extremely strong chelating/binding affinities to UO(2)(2+) using chelatin

109 s through the peripheral coordination of six chelating bipyridine linkers.

110 reaction of AlBr3 with 1 molar equiv of the chelating bis(N-heterocyclic carbene) ligand bis(N-Dipp-

111 , [Si(II)(Xant)Si(II)]Ge(0), stabilized by a chelating bis(N-heterocyclic silylene)xanthene donor lig

112 The first chelating bis(N-heterocyclic silylene)xanthene ligand [S

113 on(0) complex ("silylone") stabilized by the chelating bis(silylenyl)-ortho-carborane ligand, 1,2-(LS

114 removed effectively by forming hydrogen and chelating bonds with excess hydroxyl groups in the hydro

115 been prepared from carboxylate ions and the chelating/bridging ligand alpha-methyl-2-pyridine-methan

116 nts with hepatic metastases and flushed with chelating buffer followed by collagenase or mechanical d

117 Photolabile chelating cages or protecting groups need complex chemic

118 In live zebrafish, chelating calcium after the first wave, but before the s

119 In cultured DRG neurons, chelating calcium early in the process of WD did not alt

120 rocess of WD did not alter degeneration, but chelating calcium late in WD delayed fragmentation.

121 n spectroscopy (AAS) was used to verify iron chelating capability of nanogels.

122 nversion nanoparticles due to their stronger chelating capability to lanthanides.

123 ng ions and increasing viscosity on the iron-chelating capacity and antioxidant efficacy of this coat

124 tal complex stability, we evaluated the zinc-chelating capacity and stability of zinc complexes of wh

125 Materials retained iron-chelating capacity even in solutions of 2700 cP, similar

126 The high intracellular zinc-chelating capacity of both compounds, deduced from the m

127 ase in iron chelating capacity; however, 61% chelating capacity of materials was retained when 0.8 M

128 pectin (>/=58%), probably due to its higher chelating capacity of pro-oxidative metal ions (Fe(2+)),

129 c-binding amino acids but showed higher zinc-chelating capacity than WPH-Pap.

130 and peroxyl radicals, the reducing power and chelating capacity were, in general, in the decreasing o

131 Chelating Capacity) or EECC (EDTA Equivalent Chelating Capacity) indice according to the standard cho

132 g Capacity) and a CECC (Carnosine Equivalent Chelating Capacity) or EECC (EDTA Equivalent Chelating C

133 dispersity/stability as well as metal-cation-chelating capacity, which can not only chelate (64) Cu r

134 ABTS(+) scavenging activity and ferrous-ion-chelating capacity.

135 cium and magnesium causes a decrease in iron chelating capacity; however, 61% chelating capacity of m

136 d in Escherichia coli and purified by Nichel-chelating chromatography.

137 Recently, a nonmigratory photocurable metal-chelating coating was developed as an innovative active

138 lved in the mechanisms for the release of Fe-chelating compounds and Fe mobilization inside the plant

139 n, more specifically with biosynthesis of Fe-chelating compounds.

140 This system is evaluated in batch mode via chelating copper at the active site of tyrosinase and in

141 f detection: 0.019microM and 0.008microM for chelating copper at the active site of tyrosinase and th

142 onverting enzyme inhibitor that operates via chelating copper at the active site of tyrosinase and th

143 olling oxidative stress, we examined whether chelating copper leads to disruption of molecules involv

144 This work shows that chelating copper with CZ leads to the expression of mole

145 cium with high-affinity rhodamine-dextran or chelating cytosolic calcium with BAPTA-AM attenuated Tat

146 to wet- and dry-bonded dentin indicated that chelating dentin with chitosan for 60 s prior to bonding

147 leptic complexes of the Fe(II) d(6) ion with chelating diimine ligands.

148 s of the form [MO(PP)(2) Cl](+) (M=Mo, W; PP=chelating diphosphine) produces d(3) MO(PP)(2) Cl comple

149 3))-H activation, including requirements for chelating directing groups and high reaction temperature

150 mbinations of transition-metal complexes and chelating directing groups have been utilized to disting

151 lent kappa(2)-H2-H2SiPh2H silyl ligand and a chelating disilane ligand, and both compounds convert to

152 However, Empore chelating disks were found to give much higher recoverie

153 Copper-chelating drugs also significantly increased the number

154 glucuronoarabinoxylan in presence of calcium chelating EDTA, which would indicate that Xyn30D-CBM35 m

155 ns and thermodynamic integration we show the chelating effect to hold for coupling polymers whose rad

156 fter appropriate hydrolysis, while metal ion chelating effects were slightly attenuated.

157 We demonstrated that chelating endolysosome calcium with high-affinity rhodam

158 Additionally, metal-chelating films significantly delayed transition metal-c

159 These materials can degrade into smaller chelating fragments at rates proportional to the level o

160 phyla of the tested strains and the type of chelating functional groups (i.e., hydroxamate, catechol

161 As a proof of concept, various chelating functionalities were successfully incorporated

162 on in a hexadentate fashion using a new iron-chelating gamma-amino acid.

163 ated nanosafety of Gd-lip containing PE-DTPA chelating Gd(+3) prepared by lipid film hydration method

164 /v SMP dispersions acidified to pH 3.0 using chelating gluconic acid (GA) and CA and non-chelating hy

165 , identifying a calcium ion-binding site and chelating glutamic acid residue that mediate the formati

166 To test this hypothesis, we designed an iron-chelating glycocluster incorporating a tetrahydroxamic a

167 cording to the chemical nature of their iron-chelating group (ie, catechol, hydroxamate, alpha-hydrox

168 the identified inhibitors, including a metal-chelating group and a charged or polar moiety that could

169 e of optimized-length spacers between the Cu-chelating group and the Abeta-interacting fragments furt

170 extrapolated to substrates bearing a single chelating group, providing further insight into the reac

171 formed exclusively in the absence of this Li-chelating group.

172 Hydroxamic acids are outstanding zinc chelating groups that can be used to design potent and s

173 s as ligands that combine two distinct metal-chelating groups, lipoic acid and imidazole, for the sur

174 olymer with a high density of strong mercury chelating groups.

175 The thiol-chelating heavy metal cadmium is a highly toxic environm

176 Metal-chelating heteroaryl small molecules have found widespre

177 chelating gluconic acid (GA) and CA and non-chelating hydrochloric acid.

178 ses are involved in the biosynthesis of iron-chelating hydroxamate-containing siderophores that play

179 The two chelating IL systems (one with a pendent polyether chain

180 demonstrating that the pharmacophores of the chelating inhibitors (S)-10a, (R)-10a, and 10b were bind

181 ation mechanism involving the eight-membered chelating intermediate.

182 astrocytic syncytium was loaded with BAPTA (chelating intracellular Ca(2+)) and enhanced when high C

183 Chelating ionic liquids (ILs), in which polyether chains

184 actors linked to AD pathogenesis, namely by: chelating iron, copper and zinc; scavenging reactive oxy

185 its two terminal aryls to afford a bidentate chelating ligand (CN(tBu)Ar3NC) that is able to stabiliz

186 o-Vanillidine-2-amino-p-cresol was used as a chelating ligand and 1-undecanol was selected as an extr

187 onalization based on judicious choice of N,O-chelating ligand and metal center.

188 of the phenyl ring of 2-phenylbenzimidazole chelating ligand of the ruthenium (3a-g) and iridium com

189 anism for homogeneous catalysts in which the chelating ligand plays a key role in facilitating the ca

190 pincer complexes, supported by a tridentate chelating ligand such as terpyridyl, have been known for

191 Addition of a chelating ligand that complexes free silver ions indicat

192 lvent, extraction time, concentration of the chelating ligand, salt effect, centrifugation time and s

193 rifluoromethylation of unprotected bidentate chelating ligand, xanthine alkaloids, nucleosides, and r

194 n prepared that incorporate an anionic (N,O) chelating ligand.

195 1,3-N,O-Chelating ligands are ubiquitous in nature owing to thei

196 wrapped arrangement of the six-membered dqp chelating ligands around the Cr(III) provided nonplanar

197 These agents identified as bimetal chelating ligands binding to the active site of the enzy

198 y of amphiphilic Janus dendrimers with metal-chelating ligands conjugated to amphiphilic Janus dendri

199 A series of new P^P-chelating ligands constituted by a dicationic -[P(H2Im)2

200 or acids that have bulky or large bite angle chelating ligands deviate the most from this correlation

201 using open framework platforms with abundant chelating ligands to fabricate a series of stable metal

202 Due to its chelating ligands, Cr(CN(tBu)Ar3NC)3 is more robust than

203 adding clustering agents, such as calcium or chelating ligands, favor the lateral cis adhesion of the

204 noline), O,O (diketonate), or S,S (dithione) chelating ligands, have been characterized by X-ray crys

205 dened spectra seen with enzymes and strongly chelating ligands.

206 ynamic microbial production and loss of iron-chelating ligands.

207 Gadolinium chelating lipids were used to visualize the fine structu

208 cbl1 plants exudated less Al-chelating malate, accumulated more Al, and displayed a s

209 no-phosphanamidinate, [L](-), functions in a chelating manner, and its coordination to Y(III) results

210 ties with contrasting physical properties: a chelating metal-binding group, and a long aliphatic chai

211 ytic acid reduces mineral bioavailability by chelating minerals.

212 nd synthesis of potent but nonselective zinc-chelating MMP inhibitors (e.g., 10a and 10b).

213 extrin (beta-CD) and ferrocene (Fc) and iron chelating moieties composed of deferoxamine (DFO) into t

214 This work expands the repertoire of iron-chelating moieties in microbial siderophores.

215 ll-L-serine- (MAS3) and all-D-serine- (mas3) chelating moieties were evaluated in parallel, and a kit

216 Small iron-chelating molecules called siderophores were selected as

217 he RNase H fold with multiple distinctive Zn-chelating motifs and a unique insert, which are predicte

218 iotics and emphasizes the potential of metal-chelating natural products in antimicrobial therapy.

219 The metal-chelating noncanonical amino acid (2,2'-bipyridin-5yl)al

220 he relationship between the structure of the chelating o-alkoxybenzylidene and the observed initiatio

221 ants, such as betaine and polyols, and metal-chelating organic acids.

222 hydrido chloride complex (1), supported by a chelating P^N ligand (L1) bearing a benzannulated phenan

223 Previously, we developed a novel metal-chelating packaging film (PP-g-PAA) by grafting acrylic

224 Besides, the detection of metal-chelating peptide is not sensitive enough by spectrophot

225 This demonstrates that calcium and chelating peptides generated from the same byproduct can

226 set up an original method of screening metal chelating peptides in a hydrolysate using Surface Plasmo

227 For the first time, metal chelating peptides were screened in hydrolysates using S

228 t efficacy to selectively separate the metal-chelating peptides.

229 SO(2) and H(2)S), attributed to the strongly chelating phenolates.

230 operation between iridium(III) and a 1,3-N,O-chelating phosphoramidate ligand has been used to develo

231 multaneously on individual cells using metal-chelating polymer (MCP) based reagents.

232 s accomplished by using the metallic-complex chelating polymer Mix&Go.

233 Metal-chelating polymers (MCPs) are widely used to profile and

234 lating/binding affinities to UO(2)(2+) using chelating polymers(1,2), porous inorganic(3-5) or carbon

235 icient to induce LTP, which was prevented by chelating postsynaptic Ca(2+) or blocking nicotinic rece

236 ging activity, higher on green tea, and iron chelating potential, higher on L. algarvense.

237 avenging activity and 10-48% for the ferrous-chelating power.

238 strategy that enables to modulate the metal chelating properties of hydroxamic acid groups by bioort

239 ce of dithiothreitol is likely related to Fe chelating properties of the proligands liberated upon re

240 activity in terms of radical scavenging and chelating properties.

241 ducing ferric ions and showed the best metal chelating properties.

242 athway with metabolic intermediates of metal-chelating properties.

243 s effect is fully related to its potent iron-chelating property in the organelle.

244 onent of this host response is the manganese-chelating protein calprotectin.

245 biological coordination chemistry of Ni(II)-chelating proteins in nature and provide a foundation fo

246 -phenanthrolinium heterocycles, resulting in chelating pyridylidene remote N-heterocyclic carbene lig

247 This chelating reaction approach should find useful applicati

248 The metal elements were reacted with the chelating reagent 2,4,6-trimercapto-1,3,5-triazine (TMT)

249 using 1-(2-Pyridylazo)-2-naphthol (PAN) as a chelating reagent and detection by electrothermal atomic

250 s using 2-thenoyltrifluoroacetone (TTA) as a chelating reagent by ETAAS.

251 rom the conjugate, in the presence of strong chelating reagent ethanedithiol.

252 rstly synthesized and characterized as a new chelating reagent for determination of some metals.

253 Diethyl dithiocarbamate was used as chelating reagent.

254 ice were incubated with excess Cu or with Cu-chelating reagents; effects on cell fat content and ATP7

255 ycidyl methacrylate (GMA) based terpolymeric chelating resin was synthesized for the separation and p

256 This chelating resin was used as a new adsorbent material for

257 , volume of the sample and eluent, amount of chelating resin, and interference of ions were examined.

258 Metal ion chelating resin, or the chelators EDTA and desferrioxami

259 A new chelating resin, poly [2-(4-methoxyphenylamino)-2-oxoeth

260 A new chelating resin, poly(N-cyclohexylacrylamide-co-divinylb

261 s and then boiled in the presence of a metal chelating resin.

262 onstrate that readily available mechanically chelating rotaxanes give rise to complexes the noninterl

263 The ultrahigh thermodynamic stability of chelating S-donor ligands secures the redox-active and p

264 These include the transition metal-chelating S100 proteins, natural resistance-associated m

265 featuring pendant imidazole rings and copper-chelating salicylaldoxime, known as zinc imidazole salic

266 Neither chelating salt produced high levels of soluble protein.

267 m citrate either alone or as part of a mixed chelating salt system resulted in high levels of dispers

268 pite its simplicity, was a good indicator of chelating salt-calcium interactions in rennet casein dis

269 tudy elucidates the critical role of calcium chelating salts in modulating casein hydration and dispe

270 Thus calcium chelating salts may play a more subtle role in modulatin

271 is study investigated the effects of calcium chelating salts on calcium-ion activity (ACa(++)), calci

272 In the absence of calcium chelating salts, these concentrations were significantly

273 antly higher for matrices containing calcium chelating salts.

274 ferent in the presence or absence of calcium chelating salts.

275 reased with increasing concentration of both chelating salts.

276 nufacture of the matrices containing calcium chelating salts; with approximately 23% of total calcium

277 hat the protein backbone provides a strained chelating scaffold that tunes the [NiFe] active site for

278 or each type of oxygen-donor present in such chelating (Section 1) or bridging (Section 2) hybrid lig

279 ng copper proteins may possess His-X(aa)-His chelating sequences at their active sites and additional

280 s spectrometry-based analysis identified the chelating siderophore to be serratiochelin, a siderophor

281 e structure of xanthan, which generates more chelating sites at pH 3.5 than at pH 5.5.

282 st-effective material with a high density of chelating sites designed for mercury capture and therefo

283 ude hierarchical porosity, a high density of chelating sites, and the material's robustness, which im

284 nalized with hemilabile ligands of differing chelating strengths, allowing one to assemble them aroun

285 he feasibility of highly selective non-metal chelating, substrate-competitive inhibitors of the JmjC

286 lent attachment of a paramagnetic lanthanoid chelating tag to the ligand of interest.

287 coiled-coil peptides bearing unnatural metal-chelating terpyridine moieties.

288 ranged on one alpha-helix is responsible for chelating the first Cu(II) and that His175 stabilizes th

289 through molecular recognition of the ligands chelating the metal ions.

290 cal trials evaluating the usefulness of iron-chelating therapy in critical illness and sepsis.

291 ted, of whom 216 (84.7%) were receiving iron-chelating therapy.

292 in which imine acts as a directing group by chelating to the metal center, affords a potential route

293 the catalytically active Zn(2+) ion without chelating to the metal.

294 ts with long-standing disease requiring iron-chelating treatment and a history of splenectomy need re

295 complex (NON)AlAuP(t)Bu(3) (where NON is the chelating tridentate ligand 4,5-bis(2,6-diisopropylanili

296 very generally entails chemotypes capable of chelating two divalent metal ions in the RNase H active

297 switching the solvent (from MeCN to MeOH) or chelating unit (from bidentate to tridentate) increased

298 on the length of linker connecting the metal chelating unit to the hydroxyl group.

299 ng within the MMP-13 active site, the Zn(2+) chelating unit was replaced with nonchelating polar resi

300 rotein that exerts antimicrobial activity by chelating zinc and manganese.