ライフサイエンスコーパス: chemotactic factor

1 ferred to as T-lymphocyte-derived eosinophil chemotactic factor.

2 chamber assay using PDGF-BB (20 ng/ml) as a chemotactic factor.

3 ive tissue is a principal smooth muscle cell chemotactic factor.

4 ctivator, or the tripeptide fMLP, which is a chemotactic factor.

5 ndependent growth, while serving as a potent chemotactic factor.

6 DEP represents a new class of chemotactic factor.

7 t diseases involving leukocyte migration and chemotactic factors.

8 timulation of HMPS activity or glycolysis by chemotactic factors.

9 ng an activation by Fas ligand of neutrophil chemotactic factors.

10 platelet-activating factor, IL-8, or RANTES chemotactic factors.

11 lar endothelial cell expression of leukocyte chemotactic factors.

12 ctivated by various cytokines, stresses, and chemotactic factors.

13 enhance the respiratory burst in response to chemotactic factors.

14 sue deposition by altering the production of chemotactic factors.

15 y and profibrotic cytokines and myeloid cell chemotactic factors.

16 pid rafts, leading to expression of monocyte chemotactic factors.

17 n of major inflammatory cytokines, including chemotactic factors.

18 from infected rats was used as the source of chemotactic factors.

19 ially and temporally controlled gradients of chemotactic factors.

20 e chemotactic response of neutrophils to the chemotactic factors.

21 also inhibit leukocyte chemotaxis induced by chemotactic factors.

22 tly induced interleukin-10 (IL-10), monocyte chemotactic factor 1, IL-1beta, and tumor necrosis facto

23 nophil-derived cytokines include JE/monocyte chemotactic factor-1 and TGF-beta1, this cytokine networ

24 factor-alpha and cytokine-induced neutrophil chemotactic factor-1 in plasma were determined by enzyme

25 ta, basic fibroblast growth factor, monocyte chemotactic factor-1, and granulocyte CSF (G-CSF) had no

26 s cases are Ig light chain, AA, or leukocyte chemotactic factor 2 amyloidosis, but rare hereditary fo

27 ight chain (AL), heavy chain (AH), leukocyte chemotactic factor-2-type (ALECT2), secondary (AA), fibr

28 ability of IGF-I to serve additionally as a chemotactic factor affecting the mobility and invasive p

29 eri generated significantly higher levels of chemotactic factors after 24 h of incubation than did ex

30 hibit a hyperactive phenotype in response to chemotactic factors after cell "priming" with IL-5 famil

31 tion of reactive oxygen species and monocyte chemotactic factors after exposure of adipocytes to satu

32 ines (alveolar macrophage-derived neutrophil chemotactic factor [AMCF]-I/interleukin-8 and AMCF-II).

33 ion revealed that histamine acts as a T cell chemotactic factor and defective T cell trafficking was

34 broblast growth factor 1 (FGF-1) is a potent chemotactic factor and induces tyrosine phosphorylation

35 , cholesterol-containing diet showed reduced chemotactic factor and proinflammatory cytokine expressi

36 infection depends in part upon a gradient of chemotactic factors and adhesion molecules expressed by

37 rophils are mobilized rapidly in response to chemotactic factors and are among the first leukocytes r

38 Positive regulation of cell migration by chemotactic factors and downstream signaling pathways ha

39 contact with fibrinogen, endothelial cells, chemotactic factors and indomethacin, and treatment with

40 Alterations in the levels of chemotactic factors and other proinflammatory cytokines

41 ts the production of MCP-1, a major monocyte chemotactic factor, and either decreases or minimally in

42 due to both the resistance of neutrophils to chemotactic factors, and reduced local production of neu

43 Chemotactic factors are postulated to direct emigration

44 Furthermore, DEK functions as a chemotactic factor, attracting neutrophils, CD8+ T lymph

45 sion of adhesion molecules and production of chemotactic factors, augmenting leukocyte adhesion and r

46 In neural precursors stimulated with the chemotactic factor BDNF, Numb binds to activated TrkB, t

47 r-like growth factor (HB-EGF), a mitogen and chemotactic factor, binds to two receptor tyrosine kinas

48 nt to plastic petri dishes with the purified chemotactic factors C5a and kallikrein increased their r

49 ols the expression of cell cycle and myeloid chemotactic factors, contributing to macrophage infiltra

50 n of Th17 cells and production of neutrophil chemotactic factor CXCL1 in vitro.

51 xes resulted in expression of the neutrophil chemotactic factors CXCL1/KC, CXCL5/LIX, and CXCL8/IL-8.

52 ous PKCalpha increased the production of the chemotactic factors cytokine-induced neutrophil chemoatt

53 rming Growth Factor-beta (TGF-beta), and the chemotactic factor derived from the conditioned culture

54 The chemotactic factors differed for the PMN and J774 cells,

55 Excess glucose and SFAs regulate chemotactic factor expression by a mechanism that involv

56 uitment and activation by inducing leukocyte chemotactic factor expression from VEC.

57 ertain SFAs, but not excess glucose, trigger chemotactic factor expression via a TLR4-dependent pathw

58 ctive oxygen species generation and monocyte chemotactic factor expression.

59 HDL, and methyl-beta-cyclodextrin inhibited chemotactic factor expression.

60 icates that exposure of human neutrophils to chemotactic factor FMLP as well as granulocyte-macrophag

61 the addition of IL-5 family cytokines or the chemotactic factors fMLP, CCL5, and CCL11.

62 to the surface of leukocytes serves as a co-chemotactic factor for C5a, significantly enhancing the

63 Thus, serum levels of IL-16, a key chemotactic factor for CD4(+) lymphocytes, were reduced

64 activity with HER4; and (iii) it is a potent chemotactic factor for cells overexpressing HER4.

65 noate (5-oxoETE) is gaining recognition as a chemotactic factor for eosinophilic (Eo) as well as neut

66 fold), a chemokine initially described as a chemotactic factor for eosinophils.

67 owth factor (HB-EGF) is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells

68 c activity by itself; and (iii) it acts as a chemotactic factor for fibroblasts.

69 levated levels of circulating IL-8, a potent chemotactic factor for granulocytes and T lymphocytes, a

70 receptor CXCR3 and is known to function as a chemotactic factor for human T cells, particularly follo

71 -1alpha), is known to function in vitro as a chemotactic factor for lymphocytes, monocytes, and dendr

72 These results suggest that SDF-1 is a potent chemotactic factor for mature MKs.

73 amino-acid chemokine thought to be the major chemotactic factor for monocytes.

74 the delta subclass of chemokines, is a known chemotactic factor for monocytes/macrophages as well as

75 tivation of p38 and SYK signaling, acts as a chemotactic factor for myeloid cell migration and promot

76 e inflammatory protein 2 (MIP-2), a powerful chemotactic factor for neutrophils which is secreted by

77 Murine (Mu)Mig functioned as a chemotactic factor for resting memory and activated T ce

78 disease that, we show, also acts as a potent chemotactic factor for the migration of these leukocytes

79 CXCL12 is a key chemotactic factor for the trafficking of CLL.

80 strated that IP-10 is a potent mitogenic and chemotactic factor for vascular smooth muscle cells, the

81 blastic and osteocytic cells contain soluble chemotactic factors for bone marrow mesenchymal progenit

82 f chemokines and triggered the production of chemotactic factors for macrophages and neutrophils.

83 is suggests neutrophils may be the source of chemotactic factors for monocytes.

84 FB103A, S100 proteins like S100A7, S100A12), chemotactic factors for neutrophils (e.g. CXCL5, CXCL8)

85 Although MLO-Y4 cells secrete potent chemotactic factors for osteoclast precursors, CCL7 was

86 he Trk receptor tyrosine kinases, are potent chemotactic factors for smooth muscle cells, and the exp

87 In vitro, HepG2 cells secreted functional chemotactic factors for tumor-derived lymphocytes that c

88 (CyPA) and CyPB have been well described as chemotactic factors for various leukocyte subsets, sugge

89 lar cyclophilins have been well described as chemotactic factors for various leukocyte subsets.

90 in accordance with tissue gene expression of chemotactic factors, for which receptors are differently

91 ther, chymase induced the release of various chemotactic factors from HLFs.

92 siRNA suppressed ROS generation and monocyte chemotactic factor gene expression induced by both gluco

93 ies (ROS) in adipocytes, leading to monocyte chemotactic factor gene expression.

94 ucose-stimulated ROS generation and monocyte chemotactic factor gene expression.

95 ellular spatial information in the form of a chemotactic factor gradient is transduced into intracell

96 ory reactions, the production and release of chemotactic factors guide the recruitment of selective l

97 e structure of a small-molecule, non-peptide chemotactic factor has been determined from activity pur

98 Unlike chemotactic factors, however, AA was fully active on cel

99 an genes than is porcine alveolar macrophage chemotactic factor-II.

100 capable of migrating toward the CD4-specific chemotactic factor IL-16, providing another function for

101 as TNF-alpha, IL-1 beta, and the neutrophil chemotactic factor IL-8 and inhibitors (e.g., soluble TN

102 lar adhesion molecule-1 [ICAM-1] and soluble chemotactic factors (IL-8).

103 say revealed the presence of a single active chemotactic factor in the supernatant from this incubati

104 d monocytes, indicating that CRAMP acts as a chemotactic factor in vivo.

105 FFAs induce expression of monocyte chemotactic factors in adipocytes via both transcription

106 oblast subsets abundantly express neutrophil chemotactic factors in psoriatic skin that are subsequen

107 he PDGFbeta receptor and VSMC sensitivity to chemotactic factors in serum, leading to altered migrato

108 ability of HepG2 cells to secrete lymphocyte chemotactic factors in vitro suggests that the tumor con

109 ncrease in eotaxin, but not other eosinophil chemotactic factors, in bronchoalveolar lavage fluid aft

110 jury and in VSMCs stimulated with growth and chemotactic factors including angiotensin II, basic fibr

111 in reduced expression of numerous macrophage chemotactic factors, including CCL5.

112 anner secreted an array of T cell-recruiting chemotactic factors, including IL-8, macrophage-derived

113 a concentrations of polarizing cytokines and chemotactic factors, including interleukin-12p70 (IL-12p

114 s ERK1/2, we also observed an enhancement of chemotactic factor-induced Akt phosphorylation after IL-

115 ation and vascular permeability in models of chemotactic factor-induced alveolitis.

116 uce HUVEC expression of the potent leukocyte chemotactic factor interleukin-8 (IL-8).

117 several cellular genes, including the potent chemotactic factor interleukin-8 (IL-8).

118 imals as compared to controls, levels of the chemotactic factors interleukin-5, macrophage inflammato

119 The chemokine-like chemotactic factor leukocyte cell-derived chemotaxin 2 (

120 ficant inhibition of synthesis of the potent chemotactic factor leukotriene B4, and that process was

121 ation and renal expression of the neutrophil chemotactic factor macrophage inflammatory protein-2.

122 ha), and eotaxin, but not macrophage-derived chemotactic factor (MDC), than tissues from lymphoid hyp

123 de (ENA-78), and monocyte-derived neutrophil chemotactic factor (MDNCF).

124 duction of TNFalpha and the transcription of chemotactic factors (MIP-2, KC, S100A8/A9), vascular end

125 rotein-linked receptors for lipid or peptide chemotactic factors, neutrophils apparently also can uti

126 ed a receptor by which a non-serum-dependent chemotactic factor (NSCF) produced by C. albicans induce

127 l chemokine that can act either as a soluble chemotactic factor or as a transmembrane-anchored adhesi

128 ion also reduced the production of the mMDSC chemotactic factor osteopontin by tumor cells.

129 fied PDGF AA as the major stromal fibroblast chemotactic factor produced by tumor cells, and demonstr

130 CXCR2 chemokine receptor agonists and other chemotactic factors produced by tumors, neutrophils, and

131 CCL2, MIP-1alpha/CCL3, and RANTES/CCL5), and chemotactic factor receptors (CCR1, CCR2, and CCR5), but

132 onuclear neutrophils (PMNs) are recruited by chemotactic factors released by AMs to produce an intens

133 Chemotactic factors released by infected macrophages are

134 ainst LAM, suggesting that LAM is one of the chemotactic factors released by Mtb-infected alveolar ma

135 ions by preventing neutrophil activation via chemotactic factors released during reperfusion.

136 Local delivery of chemotactic factors represents a novel approach to tissu

137 These responses, similar to those caused by chemotactic factors, resulted from a rise in the number

138 ression and release of an epithelium-derived chemotactic factor(s) for PMN.

139 ed influx suggests the local production of a chemotactic factor(s) such as interleukin-8 (IL-8).

140 In search for chemotactic factor(s) that may mediate transmigration of

141 Chemokines are more than simple chemotactic factors, since they are also implicated in l

142 In contrast, these chemotactic factors stimulate weak or indiscernible ERK

143 vitro and in vivo towards a gradient of the chemotactic factor stromal cell-derived factor-1 (SDF-1)

144 f IL-22 strongly decreased the expression of chemotactic factors such as CCL3 and CXCL3 and of biomar

145 yperalgesia produced by BMSCs required their chemotactic factors such as CCL4 and CCR2, the integrati

146 tivates endothelial cells (EC) to synthesize chemotactic factors, such as interleukin (IL)-8.

147 induce endothelial cells (EC) to synthesize chemotactic factors, such as interleukin 8 (IL-8).

148 oline induce endothelial cells to synthesize chemotactic factors, such as interleukin 8 (IL-8).

149 GRO alpha is an inducible neutrophil chemotactic factor synthesized in inflamed corneal tissu

150 ascular smooth muscle cell (SMC) mitogen and chemotactic factor that is expressed by endothelial cell

151 ctor-like growth factor (HB-EGF) is a potent chemotactic factor that is induced during ischemia/reper

152 een described as an eosinophil and mast cell chemotactic factor that mediates a number of inflammator

153 stream to a site of infection is mediated by chemotactic factors that are often host-derived.

154 The maternal chemotactic factors that direct trophoblast migration an

155 evaluate the entire picture of all monocyte chemotactic factors that potentially contribute to adipo

156 hat tumour hypoxia induces the expression of chemotactic factors that promote tolerance.

157 n of complement and generation of complement chemotactic factors that rapidly recruit macrophages.

158 secretion by cancer cells of proinflammatory chemotactic factors that recruit antitumor effector T ce

159 blockade; these also mediate an increase in chemotactic factors that recruit T cells.

160 In this study, it is shown that a classic chemotactic factor, the bacterial chemotactic peptide N-

161 chemotactic response by preincubation with a chemotactic factor to achieve deactivation, 5 x 10(-7) M

162 The capacity of a chemotactic factor to stimulate glucose metabolism of hu

163 Interleukin (IL)-15 is a chemotactic factor to T cells.

164 Apoptotic cells secrete chemotactic factors to attract phagocytic cells, and we

165 The first chemotactic factors to be structurally defined were the

166 During stimulation with fMLP, a chemotactic factor, two Ca2+ waves traveling in opposite

167 es eosinophil responsiveness to a variety of chemotactic factors via a process called priming, althou

168 AC induces macrophage production of multiple chemotactic factors via NF-kappaB to promote monocyte mi

169 The chemotactic factor was concentrated by solid phase chrom

170 ic mAbs indicated that the serotonin-induced chemotactic factor was the previously characterized lymp

171 The release of chemotactic factors was dose dependent and was initiated

172 lthough interleukin-6 (IL-6) is not itself a chemotactic factor, we found that medium from il-6-/- ne

173 Six monocyte chemotactic factors were found to be predominantly upreg

174 g clear that there is a complex interplay of chemotactic factors, which changes over time as the infl

175 ction in direct response to locally produced chemotactic factors, which signal through specific G pro