ライフサイエンスコーパス: chick embryo

1 n of the foregut and heart tube in the early chick embryo.

2 oping auditory and vestibular ganglia of the chick embryo.

3 ral apoptosis and developmental delay in the chick embryo.

4 ng this earliest step of gastrulation in the chick embryo.

5 demonstrated in primary tumors grown in the chick embryo.

6 4D (3D+ time) confocal imaging in the intact chick embryo.

7 n mouse embryonic stem (ES) cells and in the chick embryo.

8 gressing through the primitive streak in the chick embryo.

9 bility to intravasate and metastasize in the chick embryo.

10 lanted in the posterior-lateral regions of a chick embryo.

11 the formation of the primitive streak in the chick embryo.

12 the earliest stages of hepatogenesis in the chick embryo.

13 s not sufficient for neural induction in the chick embryo.

14 ting to pattern the rostral end of the early chick embryo.

15 development of the early floor plate in the chick embryo.

16 to respond to inductive ET signaling in the chick embryo.

17 rs, i.e. "electrical coupling," in the early chick embryo.

18 l arches and great vessels of the developing chick embryo.

19 pattern very similar to that observed in the chick embryo.

20 n in multiple patterning events in the early chick embryo.

21 dies of intercellular junctions in the early chick embryo.

22 Type XX collagen mRNA is not abundant in the chick embryo.

23 g early morphogenesis of the gut tube in the chick embryo.

24 d 3D confocal time-lapse imaging in a living chick embryo.

25 or synovial joint regeneration utilizing the chick embryo.

26 ps at different stages of development in the chick embryo.

27 tribute to trigeminal sensory neurons in the chick embryo.

28 axial and epithelial expression in mouse and chick embryos.

29 nplants onto the chorioallantoic membrane of chick embryos.

30 into the vitreous cavity of embryonic day 5 chick embryos.

31 nd ALK2 in AV cushion mesenchyme in stage-24 chick embryos.

32 ial right atrial clipping on embryonic day 8 chick embryos.

33 by injecting collagenase into the eyes of E5 chick embryos.

34 c quail hindguts into the coelomic cavity of chick embryos.

35 , Six3 and Hesx1 expression, but not Otx2 in chick embryos.

36 well as animal modeling with fruit flies and chick embryos.

37 l red dye, and ablated the SHF in HH14 or 18 chick embryos.

38 ts engraft and adopt a metastatic program in chick embryos.

39 ein-2 was added to cardiogenic explants from chick embryos.

40 marrow, were infused into 1.5- to 2-day-old chick embryos.

41 edly suppressed VEGF-induced angiogenesis in chick embryos.

42 itro in RPE cell cultures derived from day 6 chick embryos.

43 mesenchymal cells explanted from stage 24-25 chick embryos.

44 tor expression in the neural plate border of chick embryos.

45 inct regions of somites 19-26 in stage 13-18 chick embryos.

46 ral tissue following NO stimulation of whole chick embryos.

47 m quails that are grafted into the coelom of chick embryos.

48 led NT-3 into the retinotectal projection of chick embryos.

49 and Pitx2c but not Pitx2b in the developing chick embryos.

50 ion when misexpressed in selected regions of chick embryos.

51 expressed along the left-right (L-R) axis in chick embryos.

52 ysed in reporter gene assays in cells and in chick embryos.

53 hicken mu-chain (VLR(PE)Tmu) into developing chick embryos.

54 nvironment during early developing stages of chick embryos.

55 A-4 and without significant toxicity toward chick embryos.

56 nd synaptic connections at various stages of chick embryos.

57 cadherin function rescues both phenotypes in chick embryos.

58 dium (PE), epicardium and EPDCs in mouse and chick embryos.

59 Notably, upon implantation into chick embryos, adult NC cells behaved similar to their e

60 g signaling inhibitor, cyclopamine (Cyc), to chick embryos after CNCC ablation and found normal heart

61 r growth in RXRalpha-null mice as well as in chick embryos after inhibition of retinoic acid synthesi

62 When the ILM was removed in E5 chick embryos, almost all GCs underwent apoptosis by E10

63 subunit mRNAs are symmetrically localized in chick embryos, an endogenous H+/K+-ATPase-dependent diff

64 ation of human NCS cells into the developing chick embryo and adult mouse hosts demonstrates survival

65 able of targeted migration in the developing chick embryo and extensive colonization of the adult mou

66 lso applied the same inducible system to the chick embryo and find that it is fully functional, sugge

67 effects of sildenafil on the fetus using the chick embryo and hypothesised that sildenafil also prote

68 asation and dissemination capacities in both chick embryo and mouse spontaneous metastasis models.

69 ic dissemination of human tumor cells in the chick embryo and used this assay to investigate the rela

70 ss diverse contexts, including cell culture, chick embryos and adult mouse brain tissue.

71 We follow somite segmentation in living chick embryos and find that the shaping process is not a

72 ariants onto the chorioallantoic membrane of chick embryos and measured levels of tumor cell intravas

73 terning ability of the FGF8b(F32A) mutant in chick embryos and murine midbrain explants shows that th

74 ock- and antisense-transfected cells in both chick embryos and nude mice models.

75 mary sites, and in spontaneous metastasis in chick embryos and nude mice.

76 Using chick embryos and primary cell culture, we examined gene

77 nd the mouse r3/r5 enhancer fails to work in chick embryos and the chick enhancer works poorly in mic

78 in vitro (cultured dorsal spinal neurons of chick embryos) and in vivo (developing chick spinal comm

79 ell-based assays in vitro and in vivo in the chick embryo, and in the neonatal and adult mouse.

80 gut by NCCs has been studied extensively in chick embryos, and genetic studies in mice have identifi

81 the spinal cord and target the cerebellum in chick embryos, and that these axons contribute to the sp

82 d into the developing eyes of day 5 to day 7 chick embryos, and their development and integration wer

83 In vivo chick embryo angiogenesis assay again confirms the antia

84 rst detailed fate maps of this region in the chick embryo are presented.

85 Chick embryos are good models for vertebrate development

86 The present study introduces the chick embryo as a model to study the role of ILM and VB

87 Here, using the chick embryo as a model, we show that, at the junction,

88 Using the chick embryo as model, we investigated whether the neck,

89 , we used cells from GFP-positive transgenic chick embryos as a source for donor tissue in grafting e

90 rtilage and bone differentiation and suggest chick embryos as a useful model to study further the rol

91 sis was studied in vivo using a quantitative chick embryo assay that measures new blood vessel growth

92 ynamic loading and aortic arch growth in the chick embryo at Hamburger-Hamilton stages 18 and 24.

93 n left ventricular (LV) myocardial strips in chick embryos at Hamburger-Hamilton stage 27 following l

94 St. 29 quail ganglia were transplanted into chick embryos at St. 9-14.

95 the FNP prior to FEZ formation by infecting chick embryos at stage 10 (HH10) with a replication-comp

96 co-culture and electroporation techniques in chick embryos between embryonic days 3 and 6, we demonst

97 Finally, in chick embryos, blocking the Wnt5a function in the caudal

98 We find that VEGF-stimulated Src activity in chick embryo blood vessels induces the coupling of focal

99 e also tested a four-channel device on fixed chick embryo Brainbow samples and identified individual

100 o a pathway for sulfur metabolism present in chick embryos but not in mammals.

101 Blocking spontaneous network activity in the chick embryo by infusing lidocaine in vivo triggers syna

102 Angiogenesis was induced on 10-day-old chick embryos by basic fibroblast growth factor (bFGF),

103 examined in retinal ganglion cells (RGCs) of chick embryos by using quantitative electron microscopic

104 cumulated in different tumor xenografts in a chick embryo CAM model.

105 cent anterior paraxial mesoderm of stage 8-9 chick embryos can be mimicked by ectopic expression of e

106 current, INa, based on 30 year old data from chick embryo cell aggregates).

107 cline on the antibody response to a purified chick embryo cell vaccine, given on a postexposure proph

108 othelial cells and neovascularization in the chick embryo chick chorioallantoic membrane (CAM) assay.

109 We used the chick embryo chorioallantoic membrane (CAM) assay to tes

110 tly reduced HepG2 tumor growth in a modified chick embryo chorioallantoic membrane (CAM) assay, assoc

111 sent study we tested the hypothesis that the chick embryo chorioallantoic membrane (CAM) can be used

112 el employing collagen onplants placed on the chick embryo chorioallantoic membrane (CAM) has been use

113 nectin, capillary formation on Matrigel, and chick embryo chorioallantoic membrane assay, bortezomib

114 of mouse aortic rings and neoangiogenesis in chick embryo chorioallantoic membrane.

115 Here, using the chick embryo close to hatching, a well-accepted model fo

116 d with Nkx2-5 and GATA4 transcripts in early chick embryos coinciding with the earliest appearance of

117 l crest cells grafted into the trunk of host chick embryos colonise the sympathetic ganglia.

118 The epiblast of the chick embryo contains cells that express MyoD mRNA but n

119 Hensen's node of the chick embryo contains multipotent self-renewing progenit

120 Under appropriate conditions, chick embryo corneal fibroblasts can produce an extracel

121 metric cell rearrangements take place within chick embryos, creating a leftward movement of cells aro

122 identified and tested using an in ovo whole chick embryo culture assay.

123 Using chick embryos cultured ex ovo, we measured: (1) changes

124 PR-1B-viruses to chick AV explants and whole-chick embryo cultures to specifically block BMP signalin

125 prospective fate maps of the endoderm in the chick embryo, delineating the origins and migrations of

126 Physical ablation of NCC in chick embryos demonstrates that survival or regeneration

127 In chick embryos, detailed fate maps have been constructed

128 al interference with Notch signalling in the chick embryo disrupts MHB formation, including downregul

129 mine endogenous patterns of BMP signaling in chick embryos during early development.

130 rived tongue mesenchyme in mouse, but not in chick, embryos during early tongue morphogenesis.

131 Here, we show that in the chick embryo, E-cadherin is weakly expressed in the epib

132 The afferents from the lagena of chick embryos (E19) to the brainstem and cerebellum were

133 In chick embryo, Ebp1 was expressed in the dermomyotome, an

134 In chick embryos, effective regeneration does not occur aft

135 stribution of beta-catenin in the developing chick embryo elicit apical ectodermal ridge and limb reg

136 Application of chick embryo extract (CEE), a rich source of trophic fac

137 ion changes induced during transformation of chick embryo fibroblasts (CEF) by the viral Jun oncoprot

138 nd protein expression are greatly reduced in chick embryo fibroblasts (CEF) transformed by v-Jun, and

139 cription in nonhepatic cell cultures such as chick embryo fibroblasts is markedly reduced compared wi

140 In chick embryo fibroblasts transformed by Rous sarcoma vir

141 Gene expression studies in mouse and chick embryos for both the Pdgfra receptor and its ligan

142 sgenic methods has limited the usefulness of chick embryos for the study of later neurodevelopmental

143 the in vitro patterns of cells derived from chick embryo forelimb and hindlimb.

144 In gain of function studies in the chick embryo, Foxc1 and Foxc2 negatively regulate interm

145 Normal chick embryos from stages 14 to 22 and sham-operated and

146 le of cEbf1 was first detailed in somites of chick embryos (from HH8 to HH28).

147 The chick embryo (Gallus domesticus) is one of the most impo

148 amics of the Notch signalling pathway during chick embryo gastrulation, which reveals a complex and h

149 ed E14.5 sciatic nerve and transplanted into chick embryos generate fewer neurons than do NCSCs isola

150 plants (from Hamburger and Hamilton stage 10 chick embryos) grown in culture.

151 t the onset of prevalve leaflet formation in chick embryos (Hamburger and Hamilton stage 20-25).

152 The chick embryo has a long and distinguished history as a m

153 The posterior marginal zone (PMZ) of the chick embryo has Nieuwkoop centre-like properties: when

154 aldh3 in the frontonasal surface ectoderm of chick embryos has been suggested to function in early fo

155 n addition to the axonal pathway, the LoC of chick embryos has privileged access to the CSF through a

156 nt study using time-lapse analysis in living chick embryos has revealed that the process of somite bo

157 Previous studies in the chick embryo have shown that sensory neurons fail to inn

158 use Hoxa3 locus in both transgenic mouse and chick embryos have identified a conserved enhancer that

159 df11 signals located around Hensen's node of chick embryos have the ability to induce profiled Hoxc p

160 model of preconditioning using the cultured chick embryo heart cells, overexpression of the RhoA-non

161 ts is markedly reduced compared with that of chick embryo hepatocytes.

162 (T3) regulation of ACCalpha transcription in chick embryo hepatocytes.

163 In a normal chick embryo, Hoxd10 and RALDH2 are expressed throughout

164 Cv-2 is expressed in the chick embryo in a number of tissues at sites at which el

165 Thus, unlike previous models proposed in the chick embryo in which Bmp4 suppresses left-sided gene ex

166 ium and cell movement during gastrulation in chick embryos in more detail.

167 n localized areas of the posterior tectum of chick embryos in ovo and analyzed the resulting changes

168 -of-function experiments were carried out in chick embryos in ovo, by intraocular overexpression of n

169 ocations and orientations in the epiblast of chick embryos in the early stages of primitive streak fo

170 growth factor (FGF)-ERK signaling pathway in chick embryos in vitro and in vivo demonstrated that blo

171 lines and in vivo in the neural tube of the chick embryo including developing motor neurones.

172 of trunk neural crest cell migration in the chick embryo, indicative of Cv-2 acting to promote BMP a

173 Chick embryos infected with retroviruses expressing an a

174 tract endocardial cushions were excised from chick embryos, infected with wild-type Shp2 or Q79R-Shp2

175 nsplanted into the neural tube of developing chick embryos, iPSCMNs selectively targeted muscles norm

176 the functional maturation of the HPS in the chick embryo is marked by a topological shift in the seq

177 lumbar motoneurons (LMNs) of the developing chick embryo is regulated in part by interactions with s

178 on the chorioallantoic membrane (CAM) of the chick embryos is critically dependent on the cleavage of

179 ssion of Hlx in the mesenchyme of developing chick embryos is highly similar to that of mouse.

180 r specifying the left-right (LR) axis in the chick embryo, is established by the repression of Shh ex

181 Zebrafish, Xenopus and chick embryos largely show consistent requirements for s

182 MicroRNA inhibition in chick embryos leads to increased BAF60a or BAF60b levels

183 idline, while ectopic expression of Slit1 in chick embryos leads to specific motor axon projection er

184 The authors developed a chick embryo lens capsular bag model to study mechanisms

185 The human tumor/chick embryo model involving grafting of human HT-1080 f

186 ed the in vivo infection of T. gondii in the chick embryo model of toxoplasmosis.

187 helial and white blood cells in vivo (ex ovo chick embryo model).

188 Using the chick embryo model, here we show that sildenafil treatme

189 In the chick embryo model, structural malformations induced by

190 o maintain their ability to metastasize in a chick embryo model.

191 ng a 3R compliant cost effective preclinical chick embryo model.

192 epted animal models of metastasis, mouse and chick embryo models, both the overexpression and knock-o

193 Chick embryos (n = 11 per group) were incubated in normo

194 ues of genes differentially expressed in the chick embryo neural crest screen retrieved the LIM domai

195 nsient ectopic expression experiments in the chick embryo, Odd1 can promote expression of the mesonep

196 nd cyclophilin B (CypB) can be isolated from chick embryos on a gelatin-Sepharose column, indicating

197 -binding protein FKBP65 can be isolated from chick embryos on a gelatin-Sepharose column, indicating

198 The ventral region of the chick embryo optic cup undergoes a complex process of di

199 1 integrins were injected intravenously into chick embryos or mice, they demonstrated increased colon

200 l role of CNBP in forebrain formation during chick embryo organogenesis.

201 In chick embryos, Pax7 is an early marker, and necessary co

202 In the early chick embryo, Pdgfa is expressed in the epiblast, outlin

203 d neurons and glia upon transplantation into chick embryos, persist throughout adult life in the mamm

204 precardiac endoderm) from gastrulation-stage chick embryos potently induces cardiac myocyte different

205 Overexpressing Snail 2 in the chick embryo prevents cyclic Lfng and Meso 1 expression

206 questions, we shifted limb buds rostrally in chick embryos prior to axon outgrowth, causing DRGs to i

207 Misexpression of mouse Six3 into chick embryos promoted the ectopic expansion of the ecto

208 e recombination experiments performed in the chick embryo provide evidence that signals operating dur

209 In chick embryos, R3 and R4 activity is upstream of the asy

210 ibition of K(ATP) in the primitive streak of chick embryos randomizes the expression of the left-side

211 ion of mutant alpha2-chimaerin constructs in chick embryos resulted in failure of oculomotor axons to

212 Endoderm ablation in the developing chick embryo results in a loss of Fgf8 expression in pre

213 emonstrate that administration of ethanol to chick embryos results in a dramatic loss of Shh, as well

214 Visual pigment (VP) expression in the chick embryo retina was investigated in ovo, in dissocia

215 photoreceptor presynaptic components during chick embryo retinal development and early posthatched l

216 nd other photoreceptor-specific genes during chick embryo retinal development in ovo, as well as in r

217 Gain- and loss-of-function studies in chick embryos reveal that the status of Runx3 expression

218 ransplantation experiments between quail and chick embryos revealed specific vascular areas as the si

219 Isolated yolk-sacs of chick embryos secreted serum proteins when incubated in

220 GGF administration to chick embryos selectively rescued Schwann cells during b

221 neurotrophin-3 serve as attractive cues for chick embryo sensory growth cones in vitro and in vivo,

222 head of frog or the cephalic neural crest of chick embryos show that Cubn is required during early so

223 on analyses, gain-of-function experiments in chick embryos show that exposure of node/head process me

224 from mouse embryos and in the neural tube of chick embryos shows that Dlx genes are sufficient to ind

225 intrinsically disordered phosphoprotein, in chick embryo skeletal development, and using circular di

226 In chick embryos, skeletal muscle formation is initiated by

227 SoxB genes in both mouse ES cells (Sox1) and chick embryos (Sox2 and Sox3) and, in both contexts, Erk

228 injected into the optic tectum of 19-day-old chick embryos, spiked with radiolabeled protein to verif

229 hat synaptic upscaling could be triggered in chick embryo spinal motoneurons by complete blockade of

230 cell intravasation, we used the human tumor-chick embryo spontaneous metastasis model to select in v

231 Robo receptors within cranial motoneurons in chick embryos strikingly perturbs their projections, cau

232 st-shock dysfunction than biphasic shocks in chick embryo studies.

233 reviously described for neural crest-ablated chick embryos, such as anomalous origin of the coronary

234 ncluded all known basal lamina proteins from chick embryos, such as laminin-1, nidogen-1, collagens I

235 tect against fetal growth restriction in the chick embryo, supporting the idea that the protective ef

236 Inhibition of Ssdp1/2 activity in mouse and chick embryos suppresses the generation of motor neurons

237 w that CNBP is expressed in tissues of early chick embryo that are the equivalent to the mouse embryo

238 We show in the chick embryo that Sdf1 expression is tightly coordinated

239 In the chick embryo, the earliest known factor is cVg1 (homolog

240 In the chick embryo, the Mnx class homeodomain protein MNR2 is

241 In the mouse and chick embryo, the node plays a central role in generatin

242 We report here that, in the chick embryo, the ventral midbrain is remarkably regular

243 In chick embryos, the ILM was enzymatically removed at embr

244 In support of this, when transplanted to chick embryos, the rabbit AVE induces anterior markers i

245 Specifically, in chick embryos these molecules are expressed in adjacent

246 sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of

247 ates cell migration of mesoderm cells in the chick embryo through at least two distinct mechanisms: c

248 ding of aggregates formed from various 7-day chick embryo tissues to cultured cell layers was analyze

249 electroporation a decade ago has helped the chick embryo to become a powerful system to study gene r

250 f progenitor cells from Hensen's node of the chick embryo to the notochord and the floor plate.

251 sculature and blood flow in living mouse and chick embryos to a depth of up to 500 microm.

252 ver, the results of experiments in mouse and chick embryos to determine its function have proved to b

253 d regulation of Hoxa3 and Hoxb3 in mouse and chick embryos to investigate how they are controlled aft

254 hicle and then grafted into age-matched host chick embryos to produce a chimeric epicardium.

255 used 3D reconstructions and cell tracing in chick embryos to show that the cardiogenic mesoderm is o

256 ave also used transgenic assays in mouse and chick embryos to test the functional activity of Hoxa2 e

257 Exposure of chick embryos to the PDGFR inhibitor imatinib mesylate r

258 Here we describe a new approach, using chick embryos, to discover organizers based on a common

259 d of Gli2;Gli3 double mutant embryos, and in chick embryos transfected with dominant activator forms

260 r-beta superfamily (TGFbeta) function in the chick embryo using Noggin, a BMP antagonist, and siRNA a

261 Blockade of Cyp26 function in the chick embryo using R115866, a specific inhibitor of Cyp2

262 When we block Notch activation in the chick embryo using the gamma-secretase inhibitor DAPT, w

263 renal epithelia and stroma in the developing chick embryo using two independent fate mapping techniqu

264 ut gain- and loss-of-function experiments in chick embryos using in ovo electroporation and found tha

265 hese markers in blastula- and gastrula-stage chick embryos, using whole-mount in situ hybridisation.

266 of apoptosis in human endothelial cells and chick embryo vasculature.

267 We used cultured chick embryo ventricular myocytes as a model to study a

268 ight SHF of Hamburger-Hamilton (HH) stage 14 chick embryos via microinjection of DiI/rhodamine and fo

269 Heart development before septation in the chick embryo was studied under two hyperglycemic conditi

270 RPE from chick embryos was cultured on filters that separated the

271 assess specificity downstream of FGF in the chick embryo we have characterised the patterns of Fgfr1

272 In the developing chick embryo we identify novel patterns in neural crest

273 and by prematurely over-expressing Runx2 in chick embryos we reduce the overall size of the craniofa

274 In early chick embryo, we found that inducing high glucose levels

275 transcriptional inhibition in the developing chick embryo, we show that beta1-integrin in the anterio

276 Using the chick embryo, we uncover novel genes in the gene regulat

277 forming grafting and ablation experiments in chick embryos, we also show that cranial paraxial mesode

278 ventricular myocytes obtained from 4-day-old chick embryos, we found that the specific activation of

279 ecies grafting experiments between mouse and chick embryos, we have shown that this process forms par

280 In chick embryos, we identified a subpopulation of NCCs tha

281 of the cranial versus trunk neural crest in chick embryos, we identified and characterized regulator

282 engrafted on the chorioallantoic membrane of chick embryos, we observed a reduction of tumour cell pr

283 ng computational modeling and experiments on chick embryos, we present evidence supporting an active

284 Using in ovo electroporation of chick embryos, we show that ectopic expression of Pdx-1

285 In chick embryos, we show that erbB4 signaling similarly ma

286 loss-of-function approaches in zebrafish and chick embryos, we show that Tbx5, in addition to its rol

287 ilic dyes to fate map the oral epithelium in chick embryos, we show that the cells that will occupy t

288 Using chick embryos, we show that the hypoxic cellular respons

289 spensions and ventricular tissue from day 16 chick embryo were collected and analyzed for comparison

290 nterference with GABA(A) receptor signaling, chick embryos were chronically treated in ovo with picro

291 Neural retinas from 5-day-old chick embryos were dissociated, cultured at low density,

292 Chick embryos were treated with the peptide Caspase inhi

293 ely dissociated retinal cells, obtained from chick embryos, were transplanted into the vitreous chamb

294 required for NC delamination in Xenopus and chick embryos, whereas they do not affect the motile pro

295 Cardiac neural crest ablation in the chick embryo, which causes structural defects of the car

296 mice and after knocking down axonal trkB in chick embryos, which can then be rescued with soluble NR

297 cells were injected into early gastrulating chick embryos, which revealed that they integrated more

298 Here, we combine experiments on chick embryos with computational modeling to explore a n

299 Treatment of chick embryos with SAG at HH14, just before the peak in

300 t not the amount of Shh produced, we treated chick embryos with the hedgehog antagonist cyclopamine a