ライフサイエンスコーパス: chimeric

1 of the mRNAs produced from a given gene are chimeric.

2 silencing efficacy, comparable to that of a chimeric 2'-OMe-pS/pO control, during in vitro bioassay

3 uence coverage dramatically (CID-only 15% vs chimeric 33%), even during discovery-based acquisition.

4 liximab (IFX), an immunogenic anti-TNF-alpha chimeric Ab, to heat stress.

5 that bound to the MARV GP the best among the chimeric Abs tested.

6 ranscriptomic and functional analyses with a chimeric AD mouse model, we find that TREM2 deletion red

7 We found that a chimeric adenoviral vector overcame the inherent resista

8 igh-throughput validation method that uses a chimeric Ag fused to the CD3zeta signaling domain expres

9 report two strategies for the fabrication of chimeric amino acid/nucleobase self-replicating macrocyc

10 Crystallization of both chimeric and full-length native heavy chain-containing A

11 Additionally, chimeric and human monoclonal antibodies (mAb) against t

12 Subsequent generation of optimized chimeric and humanized versions of these antibodies has

13 Chimeric animal models also reveal that tubulointerstiti

14 We found that when chimeric animals were fed a high-fat-diet, animals with

15 In the resulting chimeric animals, wild-type ES cells are the only source

16 ecognition of SSEA-4 by a novel monospecific chimeric antibody (ch28/11).

17 be a first-generation biomimetic five-module chimeric antigen receptor ((5M)CAR).

18 We developed an anti-CAR19 idiotype chimeric antigen receptor (alphaCAR19) to specifically r

19 immunotherapy can be highly effective, but a chimeric antigen receptor (CAR) approach would provide a

20 Using the chimeric antigen receptor (CAR) approach, here we develo

21 The chimeric antigen receptor (CAR) directs T cells to targe

22 cells (haNKs) engineered to express a PD-L1 chimeric antigen receptor (CAR) haNKs killed a panel of

23 cytoplasmic domain into a second-generation chimeric antigen receptor (CAR) improved antitumor activ

24 While therapy with T cells engineered with a chimeric antigen receptor (CAR) or a classical T cell re

25 over, PTPN2 deletion in T cells expressing a chimeric antigen receptor (CAR) specific for the oncopro

26 Chimeric antigen receptor (CAR) T cell costimulation med

27 t we believe is a novel, human CD83-targeted chimeric antigen receptor (CAR) T cell for GVHD preventi

28 tcomes during immune checkpoint blockade and chimeric antigen receptor (CAR) T cell therapeutic modal

29 Autologous chimeric antigen receptor (CAR) T cell therapies targeti

30 To improve the safety of chimeric antigen receptor (CAR) T cell therapies, microm

31 ile effective in specific settings, adoptive chimeric antigen receptor (CAR) T cell therapy for cance

32 Chimeric antigen receptor (CAR) T cell therapy has shown

33 Clinical response to chimeric antigen receptor (CAR) T cell therapy is correl

34 Chimeric antigen receptor (CAR) T cell therapy works by

35 ssessed the efficacy of a novel HIV-specific chimeric antigen receptor (CAR) T cell to target both HI

36 B7-H3.BB.z-chimeric antigen receptor (CAR) T cells administered int

37 Chimeric antigen receptor (CAR) T cells are potent drive

38 HIV-specific chimeric antigen receptor (CAR) T cells have been develo

39 Autologous chimeric antigen receptor (CAR) T cells have changed the

40 me-edited donor-derived allogeneic anti-CD19 chimeric antigen receptor (CAR) T cells offer a novel fo

41 A subset of patients treated with chimeric antigen receptor (CAR) T cells or bispecific T

42 Chimeric antigen receptor (CAR) T cells represent a pote

43 Anti-CD19 chimeric antigen receptor (CAR) T cells showed significa

44 Activated effector human T cells and chimeric antigen receptor (CAR) T cells similarly employ

45 Chimeric antigen receptor (CAR) T cells targeting B-Cell

46 Chimeric antigen receptor (CAR) T cells targeting CD19 a

47 Chimeric antigen receptor (CAR) T cells targeting CD19+

48 Here we test the therapeutic concept that chimeric antigen receptor (CAR) T cells that target sene

49 Here we explored the utility of chimeric antigen receptor (CAR) T cells, expressing the

50 means of boosting the antitumor activity of chimeric antigen receptor (CAR) T cells.

51 to immunotherapies by co-culturing GBOs with chimeric antigen receptor (CAR) T cells.

52 the largest patient cohort treated with CD22 chimeric antigen receptor (CAR) T cells.

53 Imaging strategies to monitor chimeric antigen receptor (CAR) T-cell biodistribution a

54 Innovations in chimeric antigen receptor (CAR) T-cell immunotherapies a

55 (liso-cel) is an autologous, CD19-directed, chimeric antigen receptor (CAR) T-cell product.

56 highlight their approach toward dual-antigen chimeric antigen receptor (CAR) T-cell targeting in an e

57 cel (axi-cel) is an autologous CD19-directed chimeric antigen receptor (CAR) T-cell therapy approved

58 Chimeric antigen receptor (CAR) T-cell therapy has produ

59 Chimeric antigen receptor (CAR) T-cell therapy has prove

60 Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy has shown

61 Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy has shown

62 Chimeric antigen receptor (CAR) T-cell therapy of B-cell

63 KTE-X19, an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, may have

64 nces in cellular immunotherapy, particularly chimeric antigen receptor (CAR) T-cell therapy.

65 igen escape challenges faced by conventional chimeric antigen receptor (CAR) T-cell therapy.

66 nflammation in clinically relevant models of chimeric antigen receptor (CAR) T-cell-induced cytokine

67 Chimeric antigen receptor (CAR) therapy is a promising i

68 used the scFv fragment of antibody 237 as a chimeric antigen receptor (CAR) to mediate recognition o

69 ells engineered to co-express a GD2-specific chimeric antigen receptor (CAR) with interleukin-15 in c

70 Anti-CD19 chimeric antigen receptor (CAR)-expressing T cells are a

71 Chimeric antigen receptor (CAR)-expressing T cells targe

72 Adoptive immunotherapy using B-cell-targeted chimeric antigen receptor (CAR)-modified T cells to trea

73 tive T cell therapies, including those using chimeric antigen receptor (CAR)-modified T cells, to sol

74 Chimeric antigen receptor (CAR)-T cell immunotherapy is

75 s that are loaded with tumour-specific human chimeric antigen receptor (CAR)-T cells for the treatmen

76 (2020) develop chimeric antigen receptor (CAR)-T cells targeting uPAR,

77 Chimeric antigen receptor (CAR)-T immunotherapy has yiel

78 h therapies, including blinatumomab and CD19 chimeric antigen receptor (CD19CAR) T cells, yield high

79 R-T) are genetically modified T cells with a chimeric antigen receptor directed against a specific tu

80 s, cytokine-induced memory-like NK cells and chimeric antigen receptor NK cells.

81 Sustained persistence of chimeric antigen receptor T (CAR-T) cells is a key chara

82 ophage activation syndrome (MAS) occur after chimeric antigen receptor T cell (CAR T cell) infusion a

83 Since the initial reports of chimeric antigen receptor T cell (CAR T cell)success in

84 atopoietic cell transplant and CD19-directed chimeric antigen receptor T cell (CAR T) therapy at Memo

85 can be quantified in 2-uL serum samples from chimeric antigen receptor T cell (CAR-T cell) therapy pa

86 responses to specific drugs and by modeling chimeric antigen receptor T cell immunotherapy.

87 he use of checkpoint blockade antibodies and chimeric antigen receptor T cell therapy.

88 he setting of cytokine release syndrome with chimeric antigen receptor T cell therapy.

89 Therapies employing chimeric antigen receptor T cells (CAR-T cells) targetin

90 Chimeric antigen receptor T cells (CAR-T) are geneticall

91 g low arginine microenvironment also impairs chimeric antigen receptor T cells (CAR-T) cell prolifera

92 les with the ability to recruit and activate chimeric antigen receptor T cells (CAR-Ts).

93 Chimeric antigen receptor T cells are a new and exciting

94 HA2, HER2 and interleukin 13 receptor alpha2 chimeric antigen receptor T cells as an effective treatm

95 s, radioimmunoconjugates and, more recently, chimeric antigen receptor T cells could further improve

96 we demonstrate that administration of these chimeric antigen receptor T cells into the cerebrospinal

97 Management of inflammatory toxicities of chimeric antigen receptor T cells often requires multidi

98 repertoire, somewhat analogous to engineered chimeric antigen receptor T cells, but additionally inte

99 ive cells when used as a targeting domain on chimeric antigen receptor T cells.

100 pproaches utilizing bispecific antibodies or chimeric antigen receptor T cells.

101 The anti-CD19 chimeric antigen receptor T-cell therapy tisagenlecleuce

102 treatment of cytokine storm associated with chimeric antigen receptor T-cell therapy.

103 specific viral infections, excess IL-18, and chimeric antigen receptor T-cell therapy.

104 tment using immune check inhibitors and CAR (chimeric antigen receptor) T-cell therapy serve as excel

105 ia (CLL) patients treated with CD19-targeted chimeric antigen receptor-engineered (CD19 CAR) T-cell i

106 Chimeric antigen receptor-engineered T cells targeting C

107 w targeted agents with immune regulators and chimeric antigen receptor-expressing natural killer and

108 Adoptive therapy using chimeric antigen receptor-modified T cells (CAR-T cells)

109 ata on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) t

110 Chimeric antigen receptor-T (CAR-T) cell therapies can e

111 of genetically modified T cells that express chimeric antigen receptors (CAR T cells) has generated c

112 were tested for function as third generation Chimeric Antigen Receptors (CAR) T cells demonstrating s

113 T cells engineered to express chimeric antigen receptors (CAR-T cells) have shown impr

114 Anti-CD19 chimeric antigen receptors (CARs) are artificial fusion

115 Chimeric antigen receptors (CARs) are synthetic receptor

116 ineered antibodies and T cells modified with chimeric antigen receptors (CARs) depends, among other t

117 Chimeric antigen receptors (CARs) have been used to enha

118 T cells genetically engineered to express chimeric antigen receptors (CARs) have proven - and impr

119 T cells engineered to express chimeric antigen receptors (CARs) with tumor specificity

120 e in the number of clinical trials employing chimeric antigen receptors (CARs), no comprehensive surv

121 Cells co-expressing chimeric antigen receptors and ADRs persisted in mice an

122 When equipped with epitope-defined TCRs or chimeric antigen receptors, these Lckpr-hTCL1Atg T cells

123 SS or OTC enzymes, in concert with different chimeric antigen receptors.

124 lators, and adaptive cell therapy, including chimeric antigen T-cell receptors and other novel T-cell

125 Through a chimeric approach, branched ligands also allow efficient

126 : diluted protein solution, liquid mixture, "chimeric assembly," and "multifarious assembly." In the

127 Desmoglein 3 chimeric autoantibody receptor T cells (DSG3-CAART) expr

128 or a multiplex CRISPR/Cas9 haploid screen in chimeric axolotls (MuCHaChA), which is a novel platform

129 We further showed that the chimeric BCO2 displayed broad substrate specificity and

130 Remarkably, a chimeric BET protein comprising the N-terminal half of t

131 ine, here we compared a series of mutant and chimeric BET proteins for their ability to modulate cell

132 We generated bone marrow chimeric (BMC) mice harboring either prenatally stress-e

133 e design and the synthesis of a new class of chimeric catalytic entities that would feature both cata

134 Accordingly, we exposed chimeric (CD45.2/CD45.1) mice to concentrated PM(2.5) or

135 We produced a chimeric CESA5 by replacing its N-terminal zinc finger w

136 We verified that the chimeric CESA5 explicitly interacted with all the other

137 -1, a cesa6 null mutant, were rescued by the chimeric CESA5, and became comparable to the wild type (

138 egions of CESA1, CESA3, CESA5, CESA6 and the chimeric CESA5.

139 We expressed chimeric channels composed of different components of th

140 contributing to oncogenic remodeling through chimeric circularization and reintegration of circular D

141 Populations of chimeric clusters settle much faster than floc alone, pr

142 A chimeric construct in which the C2AB domain of Syt1 was

143 of either Lhx2 or Ldb1 Electroporation of a chimeric construct that encodes the Lhx2-HD and Ldb1-DD

144 We herein report the generation of a chimeric construct, SA-CD47, encompassing the extracellu

145 ural features or a nullified function of the chimeric construct.

146 Using TAT-tagged peptides and chimeric constructs that are unable to form the intercla

147 fficacy in vitro and in vivo of a human IgG1 chimeric derivative of MAb 2C7 (2C7-Ximab) with a comple

148 We show that aggregate-prone chimeric DPR (cDPR) species underlie the divergent DPR p

149 Single-cell profiling of T(-/-) chimeric embryos shows that the anterior somites develop

150 ld-type porcine blastomeres generated viable chimeric embryos whose hematoendothelial cells were enti

151 insertion into mouse Bco2 did not impede the chimeric enzyme's catalytic proficiency.

152 designed and biochemically tested a range of chimeric enzymes, substituting parts of these B. napus D

153 te-directed mutagenesis, and construction of chimeric enzymes.

154 Using bone marrow chimeric experiments, TIPE was found to have a role in b

155 mor cell interaction with platelets produces chimeric extracellular vesicles that suppress primary tu

156 res of mutant and wild-type desmin generated chimeric filaments of seemingly normal morphology but wi

157 Using chimeric Fls2/Fls3 proteins, we found no evidence that a

158 formin-mediated elongation, we engineered a chimeric formin that binds actin monomers directly via c

159 Rilonacept, a soluble IL-1 receptor chimeric fusion protein neutralizing IL-1alpha and IL-1b

160 say, where heterologous GPCRs are coupled to chimeric G proteins, EMR2 showed broad G protein-couplin

161 es generated and validated high-contribution chimeric GEMM models using common melanoma GEMMs as a st

162 at the binding of BMS-529 to clade C soluble chimeric gp140 SOSIP (ch.SOSIP) and membrane-bound trime

163 Significantly, we demonstrate that chimeric GPCRs can be created with engineered nanobody b

164 upon agonist simulation of cells expressing chimeric GPCRs, these intrabodies first translocate to t

165 ening in the next generation to identify non-chimeric GT individuals, our method provides non-chimeri

166 recombination reports in which the original chimeric GT plants required extensive progeny screening

167 Of these constructs, the chimeric HA (cHA) vaccine with consensus H5 as globular

168 (NCT03300050), safety and immunogenicity of chimeric hemagglutinin-based vaccines were tested in hea

169 The results suggest that chimeric hemagglutinins have the potential to be develop

170 eric GT individuals, our method provides non-chimeric heritable GT in one generation.

171 Finally, ectopic expression of a chimeric HIPR-1 harboring the human HIP1 ANTH (AP180 N-t

172 Using chimeric HIV-1 constructs expressing lentiviral Nef prot

173 The expression of chimeric hnRNPA2 D290V in Caenorhabditis elegans results

174 2, reduces neurodegeneration associated with chimeric hnRNPA2 D290V.

175 NRF2 in both epithelial and stroma cells of chimeric human prostate grafts and induced premalignant

176 cap-snatched host transcripts could generate chimeric human-viral mRNAs with coding potential.

177 of the loss of distal regulatory elements in chimeric human/mouse BAC reporters.

178 Engineering chimeric, "humanized" yeast ribosomes for ES9S reveals t

179 led that the pan-group cyclic CSPs exhibit a chimeric hydrophobic patch conformation that resembles t

180 dies or infliximab (a monoclonal mouse-human chimeric IgG).

181 d by administration of N-803 to simian-human chimeric immunodeficiency virus-infected, ART-treated RM

182 ls alphaS oligomers and high-MW fibrils into chimeric intermediates with reduced toxicity.

183 The analytical utility of chimeric ion loading is demonstrated for top-down proteo

184 This ion loading technique, which we call, "chimeric ion loading", saves valuable acquisition time,

185 In contrast, betaarr1 and chimeric M2 receptor with nonphosphorylated C-terminal t

186 th the observed differences in activity, the chimeric m2/m1 VacA protein bound to cells at reduced le

187 swapping approaches to create improved ("i") chimeric mAb with enhanced tumor killing in vitro and in

188 oral and SCN rhythmicity in these temporally chimeric male mice thus enabled us to determine the cont

189 Using chimeric mapping, we demonstrate that the F2PH and F3 su

190 n interlaminar astrocytes in humanized glial chimeric mice by engrafting astrocytes differentiated fr

191 Chimeric mice deficient for Notch3 in hematopoietic cell

192 Il-18bp KO (donor)-> Il-18bp KO (recipient) chimeric mice exhibited more severe disease, with an enh

193 iological properties of scars in fetal liver chimeric mice generated using connexin43 knockout donors

194 mechanistic studies using mixed bone marrow chimeric mice identified that CD40 and CD70 but not CD80

195 toneal regimen of fluoxazolevir in humanized chimeric mice infected with HCV genotypes 1b, 2a or 3 re

196 w be routinely carried out using human-liver-chimeric mice infused with human erythrocytes to generat

197 de novo infection, HBV infected human liver chimeric mice or transgenic mice with integrated HBV gen

198 Bone marrow chimeric mice revealed that neutrophils were recruited b

199 Hematopoietic Cx43-deficient chimeric mice show reduced mitochondria transfer, which

200 Chimeric mice were produced by injecting human NC cells

201 nd cytokines in wild-type and NGAL-deficient chimeric mice with anti-MPO antibody-induced NCGN.

202 ls, whereas T cell immunity was increased in chimeric mice with NGAL-deficient neutrophils with more

203 e spectrum of ILC2s in parabiotic and shield chimeric mice, consistent with their potential role in t

204 hrombus formation was enhanced in blood from chimeric mice, suggesting that the hyperlipidemic enviro

205 g their pluripotency and ability to generate chimeric mice.

206 mp genes, mef(A) and msr(D), were present on chimeric mobile genetic elements in 99.3% of the macroli

207 xpress C7 and correct RDEB in a human:murine chimeric model.

208 In detail, we discuss chemical features of chimeric molecules and their use for targeted delivery a

209 strating optical control of proteolysis with chimeric molecules bearing photolabile or photoswitchabl

210 t advances in the rapidly expanding field of chimeric molecules leveraging chemical biology concepts.

211 member of the infraorder Anomura, reveals a chimeric morphology that incorporates features of a dome

212 To this end, we generated chimeric motors by reconstituting the MHC fast isoform (

213 luripotent stem cell (hPSC)-based microglial chimeric mouse brain model by transplanting hPSC-derived

214 Single-cell RNA-sequencing of the microglial chimeric mouse brains reveals that xenografted hPSC-deri

215 Yeast strains harboring the chimeric Mre11/Rad50 complex containing the SMC hinge of

216 Intriguingly, chimeric mRNA studies revealed that Rps28 protein, trans

217 We constructed chimeric mRNAs carrying the 3'UTR of orthologous genes a

218 We propose that chimeric mRNAs produced by alternative splicing into pol

219 Some genes exclusively produce chimeric mRNAs with transposon sequence; on average, 11.

220 to in-frame gene-gene fusions that generate chimeric mRNAs.

221 from free-living cells, creating potentially chimeric multicellular collectives, or they develop clon

222 by deletion mutagenesis and construction of chimeric mutants between gI and gD revealed that the gI

223 Our approach employs a chimeric myosin consisting of the MYO10 motor domain fus

224 nitial genetic polymers were random sequence chimeric oligonucleotides formed by untemplated polymeri

225 Moreover, chimeric oligoribonucleotides containing 2'-deoxy- or ar

226 that, in contrast to the common assumption, chimeric oncogenic transcripts-such as those involving E

227 c chromosomal fusions involving ROS1 produce chimeric oncoproteins that drive a diverse range of canc

228 ssed in mouse malaria challenge models using chimeric P. berghei parasites expressing the relevant P.

229 n one of the five classes is positioned in a chimeric pe/E position in a rotated ribosomal state.

230 Chimeric phages were engineered to attach specifically t

231 o-nanobodies (OptoNBs), a versatile class of chimeric photoswitchable proteins whose binding to prote

232 Here, we construct a chimeric Photosystem I complex in Synechocystis PCC 6803

233 A RV segment-specific (+)RNAs [(+)ssRNAs], a chimeric plasmid was transfected, from which the capping

234 mice against toxoplasmosis by (i) this novel chimeric polypeptide, containing epitopes that elicit CD

235 omparison to the parental m1 VacA protein, a chimeric protein (designated m2/m1) containing m2 sequen

236 e optical microscopy and genetic analysis of chimeric protein constructs to evaluate the binding dist

237 essing the mutant kinase B-Raf(V600E) or the chimeric protein DeltaRaf-1:ER and that MEK-ERK-sensitiv

238 s a pediatric bone cancer that expresses the chimeric protein EWSR1/FLI1.

239 The biosensor is based on a chimeric protein that combines the recognition and trans

240 We show that both types of chimeric proteins are made in IAV-infected cells, genera

241 In particular, we design chimeric proteins by hybridizing EIC from thermophilic a

242 Recombinant immunotoxins (RITs) are chimeric proteins composed of an Fv and a protein toxin

243 he impact of expressing CTCFL and CTCF-CTCFL chimeric proteins in the presence or absence of endogeno

244 dy, we generated H. pylori strains producing chimeric proteins in which VacA m1 segments of a parenta

245 we compare the performance of MHETase:PETase chimeric proteins of varying linker lengths, which all e

246 Functional analysis of HOXA1-HOXB1 chimeric proteins uncovered a novel six-amino-acid C-ter

247 of genetic rescue experiments with CSLD-CESA chimeric proteins, in vitro biochemical reconstitution,

248 We observed that a chimeric RAG-2 protein in which the mouse PHD finger is

249 Using chimeric RBD proteins, we discovered that the region enc

250 delity among different viruses by generating chimeric RdRPs from poliovirus and coxsackievirus B3.

251 rugs or mutations, or when cells expressed a chimeric receptor likely to have impaired dimerization.

252 We show that 1) chimeric receptor modules built with the ectodomains of

253 orming growth factor beta (TGF-beta) R2-41BB chimeric receptor that improved solid tumor clearance.

254 residue within the ICD of alpha3GlyRs and of chimeric receptors combining bacterial GLIC and alpha3Gl

255 by secondary immunization with RSV or with a chimeric recombinant bovine/human parainfluenza virus ty

256 n of these two gives rise to highly specific chimeric ring structures.

257 Recent studies have demonstrated that chimeric RNAs also exist in non-cancerous cells and tiss

258 Chimeric RNAs and clustered protein binding in fRIP and

259 Chimeric RNAs and their encoded proteins have been tradi

260 We experimentally validated a subset of chimeric RNAs from each classification and demonstrated

261 Here, we explored the landscape of chimeric RNAs in 9495 non-diseased human tissue samples

262 and demonstrated functional relevance of two chimeric RNAs in non-cancerous cells.

263 although large-scale, genome-wide studies of chimeric RNAs in non-diseased tissues have been scarce.

264 Importantly, our list of chimeric RNAs in non-diseased tissues overlaps with some

265 om this study provides a large repository of chimeric RNAs present in non-diseased tissues, which can

266 urther, we established means for classifying chimeric RNAs, and observed enrichment for particular cl

267 ase activity assay, we demonstrate how these chimeric RTKs, termed light-controlled human insulin rec

268 33 and EEEV-143, were solved in complex with chimeric Sindbis/EEEV virions to 7.2 angstrom and 8.3 an

269 A human-murine chimeric skin graft model constructed with KID-KCs mimic

270 Herein, we describe phosphorylation-inducing chimeric small molecules (PHICS), which enable two examp

271 MS-529 improved the immunogenicity of select chimeric SOSIP trimers and elicited tier 2 neutralizing

272 tralization changed the disease outcome of a chimeric strain expressing a vascular leak-potent NS1.

273 trans complementation of heterokaryons using chimeric structures of the CpRbp1 gene allowed for analy

274 plexes can coexist without forming erroneous chimeric structures.

275 Chimeric TMO analogues demonstrate high gene silencing e

276 Using genetic and bone marrow chimeric tools, we confirmed that hemopexin deficiency p

277 We show that this engineered chimeric toxin irreversibly cleaves and inactivates intr

278 of genes, endogenous retroviral elements and chimeric transcripts initiated from long terminal repeat

279 driver fusions beyond canonical exon-to-exon chimeric transcripts, we develop CICERO, a local assembl

280 n is a physical link in the form of abundant chimeric transposon-gene mRNAs.

281 A in hmtRNAIle or the A28:U42 base pair in a chimeric tRNA containing the anticodon stem of hmtRNASer

282 Analysis of chimeric TRPA1 proteins and mutagenesis combined reveals

283 ding to the ectopic expression of NPM-ALK, a chimeric tyrosine kinase.

284 report the design and evaluation of various chimeric vaccines based on the most common avian influen

285 associated with the virus are caused by two chimeric variants of EEHV1 (EEHV1A and EEHV1B), while tw

286 ive lack of neurotropism, we asked whether a chimeric vesicular stomatitis virus (VSV) expressing the

287 s, transient cell-to-cell fusion assays, and chimeric vesicular stomatitis virus (VSV) recombinants e

288 Chimeric vesicular stomatitis viruses with the EBOV glyc

289 To investigate this further, a chimeric virus ( XG4J) was generated by replacing the in

290 ct macaques from simian immunodeficiency HIV chimeric virus (SHIV).

291 In a simian-HIV chimeric virus AD8 (SHIVAD8) macaque model, CPT31 preven

292 ll as a replication-competent VSV/SARS-CoV-2 chimeric virus.

293 We made a panel of chimeric viruses with identical amino acid sequences but

294 Notably, sera produced against chimeric VLPs that presented swapped structural domains,

295 A chimeric VSV expressing the full-length EBOV GP (VSV-EBO

296 Using a recombinant chimeric VSV/SARS-CoV-2 reporter virus, we show that fun

297 Here, we compared chimeric VSVs in which EBOV GP replaces the VSV glycopro

298 , most transposon-containing transcripts are chimeric, which suggests that somatic expression of thes

299 meric form of programmed cell death 1 ligand chimeric with core streptavidin (SA-PDL1) that inhibited

300 tates designed to explore the effects of the Chimeric Yellow Fever Derived Tetravalent Dengue Vaccine