ライフサイエンスコーパス: chip

1 d high-performance liquid chromatography (2D chip-HPLC) approach, which enables multiple transfers fr

2 imultaneously, in multiple chambers across a chip.

3 omplex photonic circuits on the surface of a chip.

4 ole coupling that consumes no footprint on a chip and dissipates no energy, and it controls the degre

5 ic components leaving a large footprint on a chip and dissipating excessive amount of energy.

6 demands for electronic-photonic systems on a chip driven by emerging applications, including neuromor

7 nment and functionality of human organs on a chip for disease modeling and drug testing, shows great

8 ting and patterning of biological cells on a chip, exploiting the confluence of electric and thermal

9 ntly, after viral capture and detection on a chip, viruses remain viable and get purified in a microd

10 athway to create frequency comb systems on a chip.

11 In this paper, a chip-scale device consisting of piezoelectric Aluminum N

12 rporate perfused vasculature into a gut-on-a-chip (GOC) model that includes HIECs.

13 -9, using a portable and affordable lab-on-a-chip (LoC) platform, offering a promising alternative to

14 In recent years, Organ-on-a-chip (OoC) platforms have developed into promising alter

15 Human organ-on-a-chip (Organ Chip) microfluidic culture devices that reca

16 ted from three-dimensional microvessels-on-a-chip and display a more dynamic, less inflammatory respo

17 uch interest in the past decade for lab-on-a-chip applications, primarily preconcentration of biomole

18 This bile duct-on-a-chip captured essential features of a simplified bile du

19 We report a novel lab-on-a-chip device integrating a multigate electrolyte gated or

20 hip and promotes the versatility of lab-on-a-chip devices.

21 ration or purification step in many lab-on-a-chip diagnostic devices.

22 of 3D in vitro cancer models and organ-on-a-chip initiatives.

23 The WAT-on-a-chip is a multilayer device that features tissue chamber

24 ytical concept is integrated into a lab-on-a-chip microfluidic cell that allows for a high sample thr

25 is an essential consideration in organ-on-a-chip models of numerous tissues including the vascular s

26 Three-dimensional microvessels-on-a-chip models provide a unique opportunity to generate end

27 t of barrier function in these 3D organ-on-a-chip models, however, is typically limited to diffusive

28 ent of a perfusable multicellular tumor-on-a-chip platform involving different cell populations.

29 he VDA, we devised a human dorsal aorta-on-a-chip platform that identified Yes-activated protein (YAP

30 monocyte-derived macrophages, in a gut-on-a-chip platform to model the human intestine and key aspec

31 Organ-on-a-chip platforms are successfully used mainly in studies o

32 ld be used for the development of tumor-on-a-chip platforms involving heterotypic cells and their app

33 recently developed bioprinted and liver-on-a-chip platforms.

34 Brain-on-a-chip systems are designed to simulate brain activity usi

35 ively, the cellular complexity of brain-on-a-chip systems intrinsically develops cell type-specific p

36 The use of Lab-on-a-chip systems with appropriate microstructure geometry is

37 nd, in combination with appropriate Lab-on-a-chip systems, can be used as a Micro Total Analysis Syst

38 nalyzers, microfluidic devices, and lab-on-a-chip systems.

39 sive materials and the microfluidic lab-on-a-chip technology, we also present the stimuli-responsive

40 Here, we report on a bile duct-on-a-chip that phenocopies not only the tubular architecture

41 ine, we propose a novel paper-based lab-on-a-chip to deliver a cost-effective and easy to use sensing

42 luidic corticocortical neuronal network-on-a-chip to examine APP transport and localization to the pr

43 to human STIC, the gene-edited oviduct-on-a-chip, exhibited loss of cell polarization and had reduce

44 e high throughputs and customized organ-on-a-chip-like platforms along with printed 3D-cell structure

45 Mechanisms for the Development of Allergies] chip) and to timothy grass extract (ImmunoCAP).

46 architecture, being a disposable stand-alone chip, can be operated as a point-of-care test, but also

47 amount of data storage, pre-processing, and chip-to-chip communications as well as aberration-proof

48 lMix cell estimates, time of delivery, array chip and subject as random effect.

49 deposited on the surface of the ISFET array chip, yielding pixels with quasi-Nernstian sensitivity t

50 Soliton microcombs(7,8) have emerged as chip-scale frequency comb sources, and have been used in

51 When compared to bare self-assembled Au chip which was shown to exhibit a limit of detection of

52 nging from 1 to 50 nM, the AuNPs modified Au chip was proven to clearly be a better analytical tool.

53 layer (SAM) and the influence of AuNPs on Au chip for Aflatoxin B(1) (AFB(1)) detection using SPRi ap

54 The SAM Au chip was sequentially modified by EDC-NHS crosslinkers,

55 alized lipoic acid AuNPs deposited on SAM Au chips followed by in situ activation of functional group

56 yte and the detection probe into a biosensor chip leads to the formation of a sandwich-like complex o

57 Evaluation of dual biosensor chip in untreated serum samples indicated favorable simu

58 model of haematopoietic dysfunction, the BM chip may serve as a human-specific alternative to animal

59 We also show that BM chips containing cells from patients with the rare genet

60 SiC, sapphire and PSS were most affected by chipping, due to the fact that higher cutting forces wer

61 binds to the promoter region of VE-cadherin (chip assay) and is induced by VEGF in DPSCs.

62 We utilized in vitro E2F2 ChIP-chip and over expression data to identify transcriptiona

63 to a custom promoter microarray (termed ChIP-chip).

64 Validation of this ChIP-chip revealed prominent induction of ATG9A, and lucifera

65 pragingival plaque removal and chlorhexidine chips application (ChxC group) for 12 weeks, or similar

66 moval and local application of chlorhexidine chips had greater mean IPD reduction and greater percent

67 Raspberry chocolate chip ice cream was statistically associated with illness

68 of chlorhexidine gluconate 2.5 mg chip (CHX chips) as an adjunctive treatment to subgingival debride

69 ical application-specific integrated circuit chip.

70 location-specific damage response, combining chipping of outer enameloid and smooth wear of inner ena

71 ectro-optic functional elements on a compact chip that consumes only moderate power.

72 The influence on aroma compounds chips or staves and toasting degree have been analyzed i

73 functionalities without the need for custom chip fabrication.

74 his work, we introduce a new two-dimensional chip-based high-performance liquid chromatography (2D ch

75 annel, and the other in which the disposable chip is externally fixed to a reusable substrate housing

76 DNA microarrays (DNA chips) with species-specific oligonucleotide probes repr

77 surface of a micro interdigitated electrode chip, and AC electrokinetics was employed to accelerate

78 Our extracellular vesicles on demand (EVOD) chip utilizes a catalyst-free click chemistry to rapidly

79 We performed a GWAs using Human Core Exome-chip (Illumina) in 78 patients stroke patients treated w

80 We used exome-chip data to examine the associations between common and

81 he experimental framework to further explore chip-scale axon and neuron specific neural stimulation,

82 Designs for chip-based interfaces that permit this coupling are pres

83 current semiconductor foundry protocols for chip manufacturing.

84 h lasers has revealed the viability of fully chip-based soliton microcombs(18,19).

85 issipation is a fundamental issue for future chip-based electronics.

86 ave photonics, and examine how these generic chips can accelerate the development of future photonic

87 d not have been identified with a genotyping chip.

88 he liquid sample, placed on a low-cost glass chip, we cause deformations in a thin liquid layer (850

89 For achieving this, a microfluidic glass chip incorporating a monolithic separation column, a nan

90 grating a thermostat with a re-useable glass-chip comprising a chaotic mixer, an incubation channel a

91 Illumina Multi-Ethnic Global chip was used for genotyping.

92 and dairy (n = 1178) calves, using the IDBv3 chip.

93 The new dual immunosensor chip offers considerable promise for frequent decentrali

94 coating provided the following reductions in chipping area: Si (~ 23%), SiC (~ 36%), sapphire (~ 45%)

95 in reducing chips of larger size (> 41 um in chipping width), as indicated by an ~ 80% reduction when

96 s been incorporated on a photonic integrated chip.

97 produce faster and more powerful integrated chips.

98 stered nicotine (using gut, liver and kidney chips) and for intravenously injected cisplatin (using c

99 (using coupled bone marrow, liver and kidney chips).

100 The final optimized MCLW chip was formed from a total hydrogel concentration of 4

101 er version 1 (ALEX) (Macro Array Dx), MeDALL-chip (Mechanisms of Development of Allergy) (Thermo Fish

102 d efficacy of chlorhexidine gluconate 2.5 mg chip (CHX chips) as an adjunctive treatment to subgingiv

103 was measured by using the MedALL microarray chip (n = 1021).

104 well-established silicon-based microcircuit chips offers a viable route for in-sensor data processin

105 On the quadrupole ECIS microfluid chip, three typical nDEP results are observed in the fre

106 ictyostelium discoideum using a microfluidic chip design.

107 In this work, we develop a microfluidic chip formed by HGPS-SMCs generated from induced pluripot

108 ERS sensor is integrated into a microfluidic chip, achieving one-step multiplex analysis within 40 mi

109 ter sensors, distributed over a microfluidic chip, provide rapid and reliable detection of spatially-

110 reporters, and target within a microfluidic chip.

111 phoresis (ITP) implemented on a microfluidic chip.

112 capillary electrophoresis (CE)) microfluidic chip.

113 noassay implemented in a custom microfluidic chip.

114 silicon-based, capillary-driven microfluidic chip integrating two microfluidic modules for the implem

115 epithelia cultured in a dynamic microfluidic chip to create an in vitro model that recapitulated huma

116 A dual-layer paper microfluidic chip was developed as a quicker, low-cost, and field-dep

117 al interface between MS and the microfluidic chip suffered the low sample introduction efficiency, an

118 troduction of the sample in the microfluidic chip) and with high compatibility with development into

119 On the microfluidic chip, droplets were perfused with different transport-co

120 Microfluidic chips integrated with negative dielectrophoresis (nDEP)

121 t is promising for constructing microfluidic chips (lab-on-a-paper) for diagnostics and drug delivery

122 n by means of a microfluidic-based migration chip.

123 applicability of the microfluidic modulator chip is demonstrated in a heart-cut multidimensional str

124 The modulator chip allows for robust ultrahigh-pressure operation up t

125 d with 3D-Gene global miRNA microarray mouse chips encompassing all mouse miRNAs available on the San

126 lders resulting in a low cost multichambered chip.

127 Similar multilayer chip surface was prepared using functionalized lipoic ac

128 The use of reservoirs also enabled multiple chips to be run in parallel, allowing for the screening

129 reached the maximum with the 25 mum x 25 mum chip case.

130 O-glycans were then analyzed using a nanoLC-chip-QTOF mass spectrometer with a porous graphitized ca

131 t, (2) varying nanopore number in a nanopore chip, and (3) deploying the sensor in human plasma.

132 idation, a sapphire-supported (SaS) nanopore chip with a 100 times larger membrane area than conventi

133 Nanopore chips with a larger number of nanopores are shown to rec

134 ta underscores the potential of the NemaLife chip to accelerate healthspan and lifespan investigation

135 The 'NMJ chip' enables real-time, live imaging of axonal outgrowt

136 We report the first hyphenation of chip-electrochromatography (ChEC) with ion mobility spec

137 In the three cultivars, the darkening of chips was more influenced by the non-reducing sugars, in

138 s was shown to reduce the number and size of chips, regardless of the target substrate.

139 in real time for accurate quantification off chip.

140 actions, sample pretreatment to simplify off-chip analysis, and for portable spectroscopic analyses.

141 matography for the separation of alcohols on chip-based systems aiming the determination of alcoholic

142 By controlling the flow conditions on chip, the threshold of selection can be modified, enabli

143 er, performing efficient reagent exchange on chip for large numbers of embryos remains a bottleneck.

144 ferred monosaccharides can be visualized "on chip" by a 1,3-dipolar cycloaddition reaction with an al

145 On-chip acceleration provides the possibility for a complet

146 On-chip actuation and readout of mechanical motion is key t

147 On-chip microarray analysis of serum biomarkers (e.g., card

148 On-chip planar photonic waveguide-based beam engineering of

149 On-chip/on-petri dish nanoscale capacitance calibration sta

150 In addition, on-chip elusion and lysis of the protein and RNA content of

151 The platform consists of an on-chip analysis system integrated with an aerosol sampler

152 place when the focal point aligns with an on-chip detector.

153 An on-chip double emulsion method was implemented to generate

154 In this work, an on-chip electrochemical method to measure endothelial perme

155 Here, we developed an on-chip label-free method for determining the CSR.

156 Here we demonstrate an on-chip piezo-optomechanical transducer that systematically

157 perfusion and cell viability was analysed on-chip at different time points using fluorescence microsc

158 ur proposed device is able to capture and on-chip image ROR1+ cancer cells within a complex sample ma

159 n the fly, reducing power consumption and on-chip memory, and enabling protocol complexity with a hig

160 print for the next generation of Si-based on-chip optical interconnects.

161 iposomes and lipid-based nanoparticles by on-chip technologies that are applicable in a laboratory an

162 d by electronic cigarettes (e-cigarettes) on-chip.

163 a rapidly emerging field in which complex on-chip components are required to manipulate light waves.

164 Here we demonstrate a proof-of-concept on-chip transducer using trivalent ytterbium-171 ions in yt

165 We demonstrate on-chip mimicry of the BBB structure and function by cellul

166 Here, we demonstrate on-chip photon sources that simultaneously meet each of the

167 thermophila as an example, we demonstrate on-chip single-cell calorimetry measurement with metabolic

168 Our study provides a route to develop on-chip detection of optical OAM modes, which can enable th

169 For this purpose, different on-chip miRNA bioassays based on sandwich and competitive f

170 n of the clip-magazine-assembled PT-Disk, on-chip photothermal effect of PB NPs triggered both dose-d

171 lts open avenues for compact time-domain, on-chip CEP detection, and inform the development of integr

172 ith applications spanning high-efficiency on-chip lasing, frequency comb generation and modulation an

173 In this work, we demonstrate enhanced, on-chip CEP detection via optical-field-driven photocurrent

174 es in the current Internet-of-Things era, on-chip energy harvesting is highly attractive, and to be e

175 IMO antenna array shows the potential for on-chip applications at 60 GHz.

176 x 6 x 1 mm(3) that makes it suitable for on-chip implementation.

177 formation-processing technology calls for on-chip integrated sources of structured light.

178 th the mm(2) footprint area necessary for on-chip integration made from high thermoelectric figure-of

179 lacking the spatial control required for on-chip integration.

180 er torque have emerged with potential for on-chip memory, but they suffer from large energy dissipati

181 into an initially empty cavity allows for on-chip protocol development and refinement.

182 We present a new concept for on-chip separation that leverages bidirectional flow, to tu

183 Strong correlation between results from on-chip cell lysis, conventional off-line lysis and ELISA c

184 s of various qubit types, without further on-chip design changes.

185 solve unexpected challenges and biases in on-chip experiments involving particles and gas-permeable w

186 y to utilizing space-time wave packets in on-chip platforms, and enable phase-matching strategies tha

187 HF) surface-acoustic-wave (SAW) based lab-on-chip (LoC).

188 Gaussian, focused and collimated) for lab-on-chip applications of Infrared, Raman and fluorescence sp

189 Epilepsy Modelling In Vitro (MEMO), a lab-on-chip device, in which three hPSC-derived networks are se

190 dics can be hybridized into versatile lab-on-chip devices.

191 The multiplexable organic electronic lab-on-chip provides a statistically solid, reliable, and selec

192 decreasing the application barrier of lab-on-chip systems.

193 We establish a murine lung-on-chip infection model and use time-lapse imaging to revea

194 We measure on-chip quantum interference with a visibility of 0.96 +/-

195 The proposed metasurface on-chip antenna is constructed on an electrically thin high

196 The metasurface on-chip antenna is shown to exhibit an average measured gai

197 that the proposed GaAs-based metasurface on-chip antenna is viable for applications in terahertz int

198 This paper presents a novel on-chip antenna using standard CMOS-technology based on met

199 ble integrated spectroscopy using a novel on-chip hollow core waveguide platform.

200 res the optofluidic light cage as a novel on-chip sensing platform with unique properties, opening ne

201 The design space of on-chip nanophotonic components, such as an optical meta su

202 d to convergence problems and slowdown of on-chip training.

203 Organ-on-chip (OOC) devices are miniaturized devices replacing an

204 ble membranes that are required for organ-on-chip systems, therefore providing a physiological platfo

205 ich is significant development over other on-chip antenna techniques reported to date.

206 lization of efficient nonlinear processes on-chip.

207 can potentially allow a multiplexed "QCR-on-chip" technology, bringing a paradigm shift in speed, ac

208 However, the on-chip integration-a task highly relevant for future nanot

209 is only 520 nL; the total duration of the on-chip process is less than 40 min.

210 Under optimal conditions, the on-chip quantitative detection of the target DNA was readil

211 Microcarriers generated with the on-chip technique showed more sustained VEGF release profil

212 tream library preparation process through on-chip chromatin tagmentation.

213 ent a low-cost, label-free, and real-time on-chip cell counting and quantifying method for sorted/sep

214 Moreover, transient on-chip THC treatment also decreased spontaneous firing in

215 This study describes how tumor-on-chip platforms could be designed to create a heterogeneo

216 Under on-chip exposure to the psychoactive cannabinoid, Delta-9-t

217 ning the study of reaction kinetics using on-chip liquid-liquid extractions, sample pretreatment to s

218 rfused through the multi-organ human-body-on-chips.

219 Organs-on-chips (OoCs), also known as microphysiological systems o

220 erials and dried chemicals on the all-in-one chip, serum samples containing the target virus RNA were

221 tegration and systemization of chiro-optical chips in photonics, photochemistry, biomedical engineeri

222 The optimum chips were then used for the simultaneous determination

223 ric gold layer, integrated in an optofluidic chip.

224 We detail the development of an organ chip-compatible microrespirator and a smoke machine to s

225 Organ chips can recapitulate organ-level (patho)physiology, ye

226 ons of eight vascularized, two-channel organ chips (intestine, liver, kidney, heart, lung, skin, bloo

227 ultiple fluidically linked two-channel organ chips-predicts PK parameters for orally administered nic

228 d toxicity through fluidically coupled organ chips may improve the design of drug-administration regi

229 n situ microscopy imaging of up to ten organ chips inside a standard tissue-culture incubator.

230 em enables the imaging of cells in the organ chips and the repeated sampling of both the vascular and

231 oids, tissue-engineering, microfluidic organ-chips, and humanized animal systems.

232 The all-in-one paper chip can be used as a real-time quantitative assay for 5

233 e believe that the proposed all-in-one paper chip can provide a portable, low-cost, user-friendly, se

234 ultaneously detected on the all-in-one paper chip within 60 min at 65 degrees C.

235 tection is simply operated on a single paper chip.

236 The pGold chip assay achieved MI diagnostic sensitivity of 100% an

237 veloped a plasmonic gold nano-island (pGold) chip assay for diagnosis and monitoring of MI.

238 uggests future technologies such as photonic chips that can be reconfigured using non-contact pattern

239 nd its impact on the quality of sweet potato chips of cultivars with varied levels of tolerance to co

240 h future applications in neural prosthetics, chip scale neural engineering, and extensions to differe

241 mory (PCM) based synapses from our prototype chip were trained based on an event-driven learning rule

242 s with metallic glass (MG) coating to reduce chipping when used to cut Si, SiC, sapphire, and pattern

243 ng proved particularly effective in reducing chips of larger size (> 41 um in chipping width), as ind

244 Thinning down supporting substrate of rigid chip-based monolithic microwave integrated circuits has

245 rdware and its control circuitry on the same chip, providing a scalable approach towards practical qu

246 rapidly increased compared to semiconductor chip technology, for example.

247 by a simple modification of photonic sensing chips which are already on the market thus having an exc

248 ed by the realization of an exemplary sensor chip manufactured using the United Monolithic Semiconduc

249 The POC system combines a paper sensor chip and a portable instrument, which is built on an Int

250 conjunction with the disposable paper sensor chip, would have a great potential for POC detections of

251 possible through scanning of a single sensor chip on which multiple bioreactive areas have been creat

252 on a surface plasmon resonance (SPR) sensor chip to enhance the sensitivity of detecting the explosi

253 requires low-cost instrumentation and sensor chips, and is also potentially applicable to the detecti

254 click chemistry to functionalize SPR sensor chips.

255 This is because separate chips (i.e., flat image sensor array, memory device, and

256 on, and detection features on a fused silica chip in a dead volume-free manner, all extra-column peak

257 ale roughness fabricated on top of a silicon chip that monolithically integrates 4,096 microscale amp

258 strate the cointegration on a single silicon chip of the front-end electronics of NMR and ESR detecto

259 increasing the maximum power of a simulated chip by 45% at a fixed operating temperature.

260 in resonance (ESR) spectrometers on a single chip is a promising approach to improve the limit of det

261 rmanium photodetector integrated on a single chip.

262 the size of the sensing platform to a single chip.

263 f two microresonator-based DOPOs on a single chip.

264 g technology, preferably fitting on a single chip.

265 enhanced Raman scattering (SERS) on a single-chip based on inkjet dispense (ID-SERS).

266 uld allow the future extension of the single-chip DNP microsystem approach proposed here up the THz(E

267 Our HGPS-SMCs chip represents a platform for developing treatments for

268 entified, which confirmed the results of SNP chip-based CNV analysis.

269 A special chip assay was washed very gently without the traditiona

270 It features a novel stripline chip, designed to reduce the signal from the contact pad

271 The chip in its current format has a throughput of 1 muL/min

272 five tailor-made functional layers, and the chip is compatible with commercially available switching

273 xtreme ultraviolet lithography (EUV) for the chip production, where molten tin is used to generate th

274 der arterial flow conditions detach from the chip after a few days of culture; this process is mediat

275 need for purification but also improved the chip-probing quality.

276 uspended cells toward a hot-spot site of the chip, for rapid concentrating and patterning into differ

277 3 patients with the proper placement of the chip, prosthetic visual acuity was only 10% to 30% less

278 dge of the protocol before the design of the chip.

279 ng coupling to acoustic contour modes of the chip.

280 ous cell manipulations and treatments on the chip and promotes the versatility of lab-on-a-chip devic

281 from violet to infrared is coupled onto the chip via an optical-fibre array, creating an inherently

282 on probe placed on a fixed position over the chip and the reflection spectrum recorded is de-convolut

283 elds generated by electrodes surrounding the chip.

284 Reservoirs interfaced with the chip use hydrostatic pressure to passively drive flow th

285 The chips are linked through sequential robotic liquid trans

286 These chips have nanoscale features that dissipate power resul

287 The 2-mm wide, 30-mum thick chip, containing 378 pixels (each 100 mum in diameter),

288 own as microphysiological systems or 'tissue chips' (the terms are synonymous), have attracted substa

289 al to miniaturize optical frequency combs to chip scale and have the potential to revolutionize spect

290 erferometric gravitational wave detectors to chip-scale quantum micro- and nano-mechanical oscillator

291 Electrical effects due to chip-scale ultrasound delivery was discounted as the sol

292 of data storage, pre-processing, and chip-to-chip communications as well as aberration-proof light fo

293 ulas, four corn-based cereals, corn tortilla chips, and cornmeal for the presence of CP4 EPSPS.

294 we demonstrate a surface-electrode ion-trap chip(8,9) using integrated waveguides and grating couple

295 ifferent areas thickness was optimized using chips with two areas for single analyte assays.

296 the single net routing (SNR) problem in VLSI chip layout.

297 dy palinca aged with various species of wood chips.

298 le to select from a range of specific wooden chips, this work could potentially guide actors in bever

299 nd cause damaging plant diseases (e.g. Zebra chip in potatoes).

300 ies to control citrus greening, potato zebra chip and tomato vein greening diseases.