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1 matory response, early/late E2-response, and cholesterol homeostasis.
2 plays an important role in the regulation of cholesterol homeostasis.
3 iptional repressor to regulate bile acid and cholesterol homeostasis.
4 cells, is involved in maintaining organismal cholesterol homeostasis.
5 oth the enteroviral life cycle and host cell cholesterol homeostasis.
6 ngs related to the impact of SLU pathways in cholesterol homeostasis.
7 oplasmic reticulum is essential for cellular cholesterol homeostasis.
8 rption of bile acids and plays a key role in cholesterol homeostasis.
9 mportance of hepatic LXRalpha for whole body cholesterol homeostasis.
10 ol directly on major molecular parameters of cholesterol homeostasis.
11 d that statins only modestly affected cancer cholesterol homeostasis.
12 ligomeric Abeta(42) (oAbeta(42)) in neuronal cholesterol homeostasis.
13 ors (LXRs) are nuclear receptors involved in cholesterol homeostasis.
14 tic circulation of bile acids, as well as in cholesterol homeostasis.
15 iption factors involved in the regulation of cholesterol homeostasis.
16 terol that serve a central role in mediating cholesterol homeostasis.
17 ression plays an important role in adipocyte cholesterol homeostasis.
18 iological regulator of both triglyceride and cholesterol homeostasis.
19 of bile acid signaling in regulating overall cholesterol homeostasis.
20 inflammatory responses by altering cellular cholesterol homeostasis.
21 al program, which includes genes involved in cholesterol homeostasis.
22 mechanism for how these oxysterols regulate cholesterol homeostasis.
23 nd lysosomes (Ly) (LE/Ly) to globally manage cholesterol homeostasis.
24 iological set-point levels, thereby ensuring cholesterol homeostasis.
25 udies define DHR96 as a central regulator of cholesterol homeostasis.
26 o control an important regulatory pathway in cholesterol homeostasis.
27 y play a role in the oxysterol regulation of cholesterol homeostasis.
28 r (ASBT), a key membrane protein involved in cholesterol homeostasis.
29 may provide novel approaches for regulating cholesterol homeostasis.
30 feration through the maintenance of cellular cholesterol homeostasis.
31 1 inhibition and subsequent dysregulation of cholesterol homeostasis.
32 o major pathways by which the body regulates cholesterol homeostasis.
33 ole in lipoprotein metabolism and macrophage cholesterol homeostasis.
34 ng in all three of these important routes of cholesterol homeostasis.
35 density lipoproteins and plays key roles in cholesterol homeostasis.
36 ceptor (LDLR) family and functions in plasma cholesterol homeostasis.
37 LDLR SNPs may alter splicing efficiency and cholesterol homeostasis.
38 in systemic and hepatic glucose, lipid, and cholesterol homeostasis.
39 ceptor function in maintenance of whole body cholesterol homeostasis.
40 addition, bile acids play a crucial role in cholesterol homeostasis.
41 nterferes with its role in regulating plasma cholesterol homeostasis.
42 important role in maintaining bile acid and cholesterol homeostasis.
43 yl esters, regulating a key step in cellular cholesterol homeostasis.
44 ions and represents a consequence of altered cholesterol homeostasis.
45 em for the maintenance of total body fat and cholesterol homeostasis.
46 R) signaling pathway regulates bile acid and cholesterol homeostasis.
47 ellular sterol trafficking and regulation of cholesterol homeostasis.
48 polipoprotein E (apoE) is a key regulator of cholesterol homeostasis.
49 is crucial for regulating genes involved in cholesterol homeostasis.
50 ce the toxic effects of arsenic on lipid and cholesterol homeostasis.
51 It plays important roles in cellular cholesterol homeostasis.
52 crucial roles in lipoprotein metabolism and cholesterol homeostasis.
53 These findings identified a novel lncRNA in cholesterol homeostasis.
54 st in part, through the regulation of plasma cholesterol homeostasis.
55 l and phytosterols and plays a major role in cholesterol homeostasis.
56 chanisms by which PPARs influence macrophage cholesterol homeostasis.
57 ile acids, which is critical for maintaining cholesterol homeostasis.
58 retroendocytic transporter for regulation of cholesterol homeostasis.
59 or (FXR), which is an important regulator of cholesterol homeostasis.
60 R) to signal cholesterol excess and maintain cholesterol homeostasis.
61 r importance to the regulation of whole body cholesterol homeostasis.
62 totoxic death as a result of changes in cell cholesterol homeostasis.
63 that contain sterol sensors are involved in cholesterol homeostasis.
64 in transcytosis, and in regulating cellular cholesterol homeostasis.
65 oid X receptors (FXR), which are involved in cholesterol homeostasis.
66 ous literature suggests that LRP-1 regulates cholesterol homeostasis.
67 ent and synthesis rate while preserving host cholesterol homeostasis.
68 ing GM-CSF signalling, immune modulation and cholesterol homeostasis.
69 , including PCSK9, an important regulator of cholesterol homeostasis.
70 accumulation defects in cells with disrupted cholesterol homeostasis.
71 is plays a key role in regulating whole body cholesterol homeostasis.
72 f the unfolded protein response, and altered cholesterol homeostasis.
73 1, an enzyme involved in regulating cellular cholesterol homeostasis.
74 g protein recently found to be implicated in cholesterol homeostasis.
75 scription factor SREBP2, master regulator of cholesterol homeostasis.
76 and over time causes disruption in cellular cholesterol homeostasis.
77 hile LXRalpha has its most marked effects on cholesterol homeostasis.
78 multiple pan-coronavirus factors involved in cholesterol homeostasis.
79 development of mechanisms for intracellular cholesterol homeostasis.
80 iptional regulators of cellular and systemic cholesterol homeostasis.
81 ne expression associated with the control of cholesterol homeostasis.
82 , as well as phosphoinositide signalling and cholesterol homeostasis.
83 ular Loop1-Loop7 binding, a central event in cholesterol homeostasis.
84 e diet to characterize the role in lipid and cholesterol homeostasis.
85 fflux from cells and regulates intracellular cholesterol homeostasis.
88 levels in cell cultures requires normal cell cholesterol homeostasis; 2) HA degradation may contribut
91 ed LDL/cholesterol and altered intracellular cholesterol homeostasis also causes chromosomal instabil
92 rosclerosis, we have asked whether disrupted cholesterol homeostasis alters HA accumulation in low de
94 d with I1061T-NPC1 leading to restoration of cholesterol homeostasis, an effect that is largely drive
95 These findings reveal Nrf1 as a guardian of cholesterol homeostasis and a core component of adaptive
97 ings identify ABCG1 as a novel integrator of cholesterol homeostasis and adaptive immune programs.
98 demonstrates that adipose LAL drives tissue-cholesterol homeostasis and affects BAT metabolism, sugg
99 ernative splicing as a modulator of cellular cholesterol homeostasis and as an underlying mechanism o
102 he critical role of beta-cell ABCA1 in islet cholesterol homeostasis and beta-cell function and highl
105 phan nuclear receptor (NR5A2) that regulates cholesterol homeostasis and cell plasticity in endoderma
107 y lipoprotein receptor (LDLR) is crucial for cholesterol homeostasis and deficiency in LDLR functions
108 et al. here identify effects of Wolbachia on cholesterol homeostasis and dengue virus replication in
109 rogenitor cells (OPCs), Lrp1 is required for cholesterol homeostasis and differentiation into mature
110 ation-defective RID-alpha mutant deregulates cholesterol homeostasis and elicits lysosomal storage ab
112 e Tangier disease characterized by defective cholesterol homeostasis and high density lipoprotein (HD
114 mechanism by which perturbation of beta-cell cholesterol homeostasis and impaired insulin secretion i
115 regulating both macrophage inflammation and cholesterol homeostasis and implicate IL-19 as a link be
116 the physiological significance of UBIAD1 in cholesterol homeostasis and indicate inhibition of HMGCR
120 s an important role in controlling lipid and cholesterol homeostasis and is a potential target for th
121 in high density lipoprotein (HDL) regulates cholesterol homeostasis and is protective against athero
122 for participation of small noncoding RNAs in cholesterol homeostasis and is the first to implicate a
123 preclinical data, focusing on alterations in cholesterol homeostasis and its consequent effect on pat
124 role of microbiota in regulating whole-body cholesterol homeostasis and its response to a cholestero
129 s; however, a potential link between altered cholesterol homeostasis and platelet production has not
130 a and beta are transcriptional regulators of cholesterol homeostasis and potential targets for the de
131 epatic FXR by FGF15/19-induced Src maintains cholesterol homeostasis and protects against atheroscler
132 These results reveal a new facet of cellular cholesterol homeostasis and provide a potential explanat
133 ing how SHP interacts with LRH-1 to regulate cholesterol homeostasis and provide new insights into ho
134 obesity is associated with abnormal hepatic cholesterol homeostasis and resistance to leptin action.
135 concert with the SREBP host genes to control cholesterol homeostasis and suggest that miR-33 may repr
136 development of atherosclerosis by regulating cholesterol homeostasis and suppressing inflammatory gen
137 ificance of hepatic CPR-dependent enzymes in cholesterol homeostasis and systemic drug clearance, and
138 ion in caveolae via actions on both membrane cholesterol homeostasis and the level of activation of t
139 have been implicated in regulating cellular cholesterol homeostasis and therefore play critical role
141 Cyp7a1 plays a critical role in maintaining cholesterol homeostasis and underscores the importance o
142 , type I (SR-BI) in the modulation of global cholesterol homeostasis and vascular cell function, and
143 rter ABCG1 has an essential role in cellular cholesterol homeostasis, and dysregulation has been asso
145 ng their own biosynthesis, lipid absorption, cholesterol homeostasis, and local mucosal defenses in t
146 ous biochemical processes such as secretion, cholesterol homeostasis, and regulation of chromatin str
147 ear receptors that are central regulators of cholesterol homeostasis, and synthetic LXR agonists have
148 trol of growth signaling pathways, lipid and cholesterol homeostasis, and the breakdown of xenobiotic
149 targets the Golgi complex and disrupts cell cholesterol homeostasis, and this action of Abeta-(1-42)
150 lipoproteins, how it helps maintain cellular cholesterol homeostasis, and, finally, how it is catabol
151 ctions, including autophagosome degradation, cholesterol homeostasis, antigen presentation, and cell
152 of Wwox involve multiple pathways, including cholesterol homeostasis, ApoA-I/ABCA1 pathway, and fatty
153 tion of lipofuscin bisretinoids and abnormal cholesterol homeostasis are implicated in macular degene
155 sphatidylinositol phosphate biosynthesis and cholesterol homeostasis as critical host pathways suppor
156 eptor agonists, which regulate intracellular cholesterol homeostasis, augment PKA agonist- or high ph
157 erferes with normal human cell life, such as cholesterol homeostasis, blood coagulation, EGFR binding
158 ole for Aup1 in maintenance of intracellular cholesterol homeostasis, but they also highlight the clo
159 ts demonstrate that changes in intracellular cholesterol homeostasis by ABCG1 profoundly impact iNKT
160 that selected dietary plant sterols disrupt cholesterol homeostasis by affecting two critical regula
161 n receptor (LDLR) plays a key role in plasma cholesterol homeostasis by binding and internalizing lip
162 plasmic reticulum that play crucial roles in cholesterol homeostasis by inhibiting excessive choleste
163 he gallbladder may have a role in regulating cholesterol homeostasis by modulating the physical forms
164 and pro-oxidative factor, alters macrophage cholesterol homeostasis by repressing ABCA1 to promote f
165 the endoplasmic reticulum (ER) that controls cholesterol homeostasis by transporting sterol regulator
166 tion that MDCKII cells respond to changes in cholesterol homeostasis by up-regulating a pathway for c
167 Moreover, drug-induced perturbations of cholesterol homeostasis cause mitochondrial DNA disorgan
169 n localization with such varied processes as cholesterol homeostasis, cell signalling and cytokinesis
170 F therefore plays a central role in cellular cholesterol homeostasis coordinating Rab7 activation, en
171 f CETP biosynthesis in cells alters cellular cholesterol homeostasis, demonstrating an intracellular
172 tion, the extent to which it impacts hepatic cholesterol homeostasis depends on cholesterol intake.
173 tors function as bidirectional regulators of cholesterol homeostasis, driving efflux when cholesterol
175 R-125a-5p have been implicated in regulating cholesterol homeostasis, fatty acid metabolism and lipog
176 l in cancer, with several demonstrating that cholesterol homeostasis genes can modulate development.
177 differential expression of inflammatory and cholesterol homeostasis genes in the macrophage subpopul
180 odeling, we found that daidzein enhanced the cholesterol homeostasis genetic program, including Lxr a
181 ant roles in the regulation of bile acid and cholesterol homeostasis, glucose metabolism, and insulin
184 s (LXRs), one cellular mechanism to regulate cholesterol homeostasis, has been found to alter Abeta l
185 Apolipoprotein E (ApoE), a key ligand for cholesterol homeostasis, has been shown to interact with
189 d its apolipoproteins in regulating cellular cholesterol homeostasis, highlighting recent advances on
191 the products of which control bile acid and cholesterol homeostasis; however, the role of DRIP205 in
193 rovided evidence for the alteration of brain cholesterol homeostasis in 129.Mecp2-null mice, an exper
197 We found that CtBP regulates intracellular cholesterol homeostasis in breast cancer cells by formin
198 ypes suggested a potential role of disrupted cholesterol homeostasis in cancer development but additi
200 -apoE interactions may contribute to overall cholesterol homeostasis in cells and tissues that expres
201 ke-induced behavioral deficits via enhancing cholesterol homeostasis in chronic stroke, and this occu
202 n-2 and -1 genes, respectively, and regulate cholesterol homeostasis in concert with their host genes
205 tractable tool to explore the complexity of cholesterol homeostasis in eukaryotic cells and to devel
206 ive of oxidative stress and dysregulation of cholesterol homeostasis in fish from polluted sites.
207 xpression of NRs and other genes involved in cholesterol homeostasis in freshly isolated and cultured
209 eased cholesterol activates LXRs to maintain cholesterol homeostasis in highly-dense glioblastoma cel
210 tical role for pancreatic beta cell-specific cholesterol homeostasis in insulin secretion as well as
214 SORT1 may be beneficial in improving hepatic cholesterol homeostasis in metabolic and inflammatory li
215 BP-dependent gene regulation governing lipid/cholesterol homeostasis in metazoans in response to fast
216 ptor protein expression, and restored plasma cholesterol homeostasis in mice lacking a functional liv
217 vious studies suggest that AHR ligands alter cholesterol homeostasis in mice through repression of ge
222 ivity and support the importance of cellular cholesterol homeostasis in regulating beta-cell insulin
229 gest that, in addition to the involvement in cholesterol homeostasis in the brain, this enzyme may pa
231 anizing principle for signaling pathways and cholesterol homeostasis in the cell, relatively little i
232 an essential role in maintaining peripheral cholesterol homeostasis in the context of hypercholester
235 ng cassette transporter G1 (ABCG1) regulates cholesterol homeostasis in thymocytes and peripheral CD4
236 he first report that cowpea peptides inhibit cholesterol homeostasis in vitro in two distinct routes,
239 n ileal FGF15/19 to hepatocyte FGFR4 axis in cholesterol homeostasis, in metabolic homeostasis in viv
240 the integration of mitochondria in cellular cholesterol homeostasis, in which ATAD3 plays a critical
241 lic disorders associated with aberrant lipid/cholesterol homeostasis, including metabolic syndrome an
242 s of CYP27A1 led to dysregulation of retinal cholesterol homeostasis, including unexpected upregulati
244 eport validation of Usf1 as a causal gene of cholesterol homeostasis, insulin sensitivity and body co
245 d the potential of therapeutically targeting cholesterol homeostasis is a controversial area in the c
246 atients and mice models of AD suggested that cholesterol homeostasis is altered in neurons that accum
251 In light of our findings we postulate how cholesterol homeostasis is maintained within the cell an
256 olesterol is present in the plasma membrane, cholesterol homeostasis is principally regulated through
260 of seminiferous epithelium, and disorder of cholesterol homeostasis, is uniformly accelerated upon i
261 >300 variants in the NPC1 gene that disrupt cholesterol homeostasis leading to the rapid onset and p
262 a number of biological processes, including cholesterol homeostasis, lipid metabolism, and keratinoc
264 ctions related to nucleoid and mitochondrial cholesterol homeostasis, modified the distribution of ch
265 perfamily whose members function in cellular cholesterol homeostasis (Niemann-Pick C1) and Hedgehog s
266 ite the significance of this interaction for cholesterol homeostasis, no structure of either ARH or t
267 uclear liver X receptor (LXR) helps maintain cholesterol homeostasis, not only through promotion of c
269 These results suggested that intrapulmonary cholesterol homeostasis, other than systematic cholester
271 ignaling plays a role in modulating cellular cholesterol homeostasis, PM biophysical properties, and
272 regulatory mechanism contributes to maintain cholesterol homeostasis preventing excessive cholesterol
273 ovel, cell cycle mechanism by which aberrant cholesterol homeostasis promotes neurodegeneration and a
275 hibition of phosphatidylinositol kinases and cholesterol homeostasis reduced replication of all three
278 regulate variant trafficking, stability, and cholesterol homeostasis, results consistent with the rol
279 ntified a dysregulation of genes involved in cholesterol homeostasis, some of them being liver X rece
280 leviates mitochondrial dysfunction, aberrant cholesterol homeostasis, striatal atrophy, impaired dopa
281 idence support the notion that alteration of cholesterol homeostasis strongly predisposes to Alzheime
282 decrease in ubiquinone levels and changes in cholesterol homeostasis suggest that mevalonate pathway
284 receptors are involved in the regulation of cholesterol homeostasis, the combination of higher chole
285 Treatment with 5-AzaC disturbed subcellular cholesterol homeostasis, thereby impeding activation of
286 In contrast, wild-type animals maintained cholesterol homeostasis through basal expression of gene
287 HIV-1 transcription in T cells is linked to cholesterol homeostasis through control of TFII-I expres
288 through which the biological clock regulates cholesterol homeostasis through its regulation of non-rh
289 olecules that play a major role in mediating cholesterol homeostasis through mechanisms which have no
290 post-transcriptional mechanisms that assure cholesterol homeostasis through their sterol-induced bin
291 ntial role in LDL-C (low-density lipoprotein cholesterol) homeostasis through regulating the PCSK9 (p
293 olecular basis for the link between Arf6 and cholesterol homeostasis using an inducible knockout (KO)
294 volved in cholesterol synthesis and cellular cholesterol homeostasis using comprehensive two-dimensio
296 ons contribute to the regulation of cellular cholesterol homeostasis, we synthesized the enantiomer o
298 renatal growth and nutrition influence adult cholesterol homeostasis, whether prenatal growth modifie
299 inding protein (OSBP) regulate intracellular cholesterol homeostasis, which is required for many viru
300 nistically link the regulation of macrophage cholesterol homeostasis with defective efferocytosis.