ライフサイエンスコーパス: chondroitin 4-sulfate

1 e glycosaminoglycan is made predominantly of chondroitin 4-sulfate.

2 an sulfate, heparan sulfate, chondroitin, or chondroitin 4-sulfate.

3 ains (HC1 and HC2) covalently linked through chondroitin 4-sulfate.

4 ted that Ihh interacts with CS, particularly chondroitin-4-sulfate.

5 ture and that the predominant type of CS was chondroitin-4-sulfate.

6 using heparins of different size, as well as chondroitin 4-sulfate and dermatan sulfate as the GAG po

7 -sulfate groups from the non-reducing end of chondroitin 4-sulfate and dermatan sulfate.

8 SP contains glycosaminoglycan chains made of chondroitin-4-sulfate and has an average of 31-32 disacc

9 ycosaminoglycan polyanions, such as heparin, chondroitin 4-sulfate, and dermatan sulfate.

10 ratan sulfate) may catalyze the sulfation of chondroitin 4-sulfate as alternative substrate.

11 sizes chondroitin 6-sulfate rather than only chondroitin 4-sulfate as wild-type cells.

12 oint to glycosaminoglycans, and specifically chondroitin 4-sulfates, as a novel class of immunologica

13 oiting pregnant rats as a model for studying chondroitin 4-sulfate-based therapeutics for human place

14 In the presence of chondroitin-4-sulfate (C-4S), the CA value increased 200

15 We have demonstrated that chondroitin 4-sulfate (C4-S) promotes autoprocessing of

16 rtilage-resident glycosaminoglycans, such as chondroitin 4-sulfate (C4-S).

17 ist in the extracellular matrix, and include chondroitin 4-sulfate (C4S) and chondroitin 6-sulfate (C

18 The chondroitin 4-sulfate (C4S) chains of very low sulfated

19 A dodecasaccharide motif of the low-sulfated chondroitin 4-sulfate (C4S) mediate the binding of Plasm

20 protein 1 named VAR2CSA to the low sulfated chondroitin 4-sulfate (C4S) proteoglycan (CSPG) present

21 quirements for the adherence and the minimum chondroitin 4-sulfate (C4S) structural motif that suppor

22 rageenan (1 mug/ml for 24 h), degradation of chondroitin 4-sulfate (C4S) was inhibited, leading to ac

23 Content of total sulfated GAG (sGAG), chondroitin 4-sulfate (C4S), and total chondroitin sulfa

24 ls (IRBCs) sequester in the placenta through chondroitin 4-sulfate (C4S)-mediated adherence.

25 loss of parasitized erythrocytes adhering to chondroitin 4-sulfate (C4S).

26 lfatase; ARSB) removes 4-sulfate groups from chondroitin-4-sulfate (C4S) and dermatan sulfate and is

27 h the glycosaminoglycan chains of CSPGs, and chondroitin-4-sulfate (C4S) is the predominant sulfated

28 's dermatomyositis (DM) lesions is primarily chondroitin-4-sulfate (C4S), which is immunomodulatory i

29 (IRBCs) in the human placenta is mediated by chondroitin-4-sulfate (C4S).

30 [HA] and chondroitin [C0S]), sulfated GAGs (chondroitin-4-sulfate [C4S], chondroitin-6-sulfate [C6S]

31 d host red blood cells and binds to specific chondroitin-4-sulfate chains of the placental proteoglyc

32 tes sequester in the placenta by adhering to chondroitin 4-sulfate, creating a risk factor for both t

33 roteoglycan, namely serglycin, that contains chondroitin 4-sulfate (CS) glycosaminoglycans is present

34 The chondroitin-4-sulfate (CS) chain attached to Ser(10) was

35 C digestion (P < .05) and by the addition of chondroitin-4-sulfate (CS) or heparin in excess quantiti

36 First, sulfated oligosaccharides such as chondroitin-4-sulfate (CS) were efficiently isolated fro

37 in the order of heparin > heparan sulfate > chondroitin-4-sulfate = dermatan sulfate = dextran sulfa

38 In this study, we show that two chondroitin 4-sulfate forms, CSA and CSB, can activate d

39 hesion of infected erythrocytes to placental chondroitin 4-sulfate in primigravid women.

40 SA, a PfEMP1 that mediates IRBC adherence to chondroitin 4-sulfate in the placenta.

41 in the area, suggesting multiple origins of chondroitin-4-sulfate increase.

42 Although chondroitin 4-sulfate is known to mediate IRBC adherence

43 m infection in pregnant women results in the chondroitin 4-sulfate-mediated adherence of the parasite

44 omain protein that requires a minimum 12-mer chondroitin-4-sulfate molecule for specific, high affini

45 eceptors for IRBC adhesion, which involves a chondroitin 4-sulfate motif consisting of six disacchari

46 secreted sulfated GAGs, including decreased chondroitin-4-sulfate, present in Bpnt2-KO MEFs.

47 Chondroitin 4-sulfate proteoglycans constitute the predo

48 an increase in the chondroitin-6-sulfate to chondroitin-4-sulfate ratio of GAG chains on versican, a

49 ores that can each accommodate the 12-mer of chondroitin-4-sulfate, suggesting a model for receptor b

50 flammation promotes the transfer of HCs from chondroitin 4-sulfate to hyaluronan by tumor necrosis fa

51 Chondroitin sulfate A (CS-A, also known as chondroitin-4-sulfate) was used as the substrate for the

52 igher concentrations of dermatan sulfate and chondroitin 4-sulfate were required with an IC(50) of 2,