ライフサイエンスコーパス: chondroitin sulfate

1 nts of heparin accompanied by a reduction of chondroitin sulfate.

2 ycosaminoglycans such as heparan sulfate and chondroitin sulfate.

3 old) toward heparin over hyaluronic acid and chondroitin sulfate.

4 cosaminoglycans, such as hyaluronic acid and chondroitin sulfate.

5 onic Hh complexes with two GAGs, heparin and chondroitin sulfate.

6 cylation, increased synthesis of both HA and chondroitin sulfate.

7 dulterant or contaminant, e.g., oversulfated chondroitin sulfate.

8 rization in solution, which was inhibited by chondroitin sulfate.

9 ran sulfate (HS), dermatan sulfate (DS), and chondroitin sulfate.

10 o showed increased decorin and production of chondroitin sulfate.

11 ocytosis of HA, Hep, AcLDL, or DS but not by chondroitin sulfates.

12 ree than on surfaces coated with dermatan or chondroitin sulfates.

13 fixed combination of xanthan gum 0.09 % and chondroitin sulfate 0.1 % (XG/CS) ophthalmic solution (n

14 itro using a previously established collagen-chondroitin sulfate 3D scaffold.

15 tan sulfate (KS), dermatan sulfate (DS), and chondroitin sulfate A (CSA) and C (CSC), polymerized in

16 villous spaces of the placenta by binding to chondroitin sulfate A (CSA) and elicit inflammatory resp

17 erythrocytes (IEs) that selectively bind to chondroitin sulfate A (CSA) and sequester in placental t

18 ocytes that adhere to the placental receptor chondroitin sulfate A (CSA) and sequester in the placent

19 ciparum-infected erythrocytes, and placental chondroitin sulfate A (CSA) are primarily responsible fo

20 ich mediates adherence of red blood cells to chondroitin sulfate A (CSA) in the placenta.

21 ncipal ligand associated with the binding to chondroitin sulfate A (CSA) that allows placental seques

22 alciparum-infected erythrocytes to placental chondroitin sulfate A (CSA) through the PfEMP1-VAR2CSA p

23 glycans (GAGs) include keratan sulfate (KS), chondroitin sulfate A (CSA), and hyaluronic acid (HA).

24 hesion of VAR2CSA-expressing erythrocytes to chondroitin sulfate A (CSA)-a major criterion for evalua

25 chia pastoris and developed a panel of seven chondroitin sulfate A (CSA)-binding parasites from diver

26 2CSA, a parasite antigen that interacts with chondroitin sulfate A (CSA).

27 responsible for binding to the placenta via chondroitin sulfate A (CSA).

28 he presence of the contaminant, oversulfated chondroitin sulfate A (OSCS), in heparin.

29 over dextran sulfate, dermatan sulfate, and chondroitin sulfate A and C.

30 SA expressed on infected red blood cells and chondroitin sulfate A in an in vitro binding-inhibition

31 thereby promoting amyloid formation, whereas chondroitin sulfate A kinetically traps partially unfold

32 Second, C1INH bound to host CD36 and chondroitin sulfate A molecules, interfering with cytoad

33 e antigen VAR2CSA (variant surface antigen 2-chondroitin sulfate A) is expressed on infected erythroc

34 be our results of HC transfer experiments to chondroitin sulfate A, chemically desulfated chondroitin

35 major glycosaminoglycans, including heparin, chondroitin sulfate A, dermatan sulfate, and OSCS.

36 ed multivariate analysis, including heparin, chondroitin sulfate A, dermatan sulfate, and the infamou

37 d, partially sulfated, or fully oversulfated chondroitin sulfate A, dermatan sulfate, or heparan sulf

38 variant surface antigen that binds placental chondroitin sulfate A, have been suggested to mediate pr

39 escribes the separation of dermatan sulfate, chondroitin sulfate A, heparin, and the semisynthetic fu

40 of Hic to hTSP-1 is inhibited by heparin and chondroitin sulfate A, indicating binding to the N-termi

41 nfected erythrocytes and mediates binding to chondroitin sulfate A, initiating inflammation and disru

42 Chondroitin sulfate A, on the other hand, showed a stron

43 (IEs) that surface-express VAR2CSA and bind chondroitin sulfate A.

44 basic peptides (FS2 and NFS3) to heparin and chondroitin sulfate A.

45 e-3-phosphate dehydrogenase aggregation, but chondroitin sulfates A, B, and C together with dextran s

46 Chondroitin sulfate, a common dietary supplement, increa

47 ratan sulfate and a concomitant reduction in chondroitin sulfate accumulation in the posterior palata

48 Copigmented complexes of chondroitin sulfate and anthocyanin were preloaded in Ca

49 M compartments, represent the main source of chondroitin sulfate and are fundamental for the constitu

50 ibrin(ogen) is predominantly mediated by the chondroitin sulfate and dermatan sulfate on CD44.

51 odified glycosaminoglycans (e.g. fucosylated chondroitin sulfate and fucoidan), nothing is known abou

52 ne a key requirement for the balance between chondroitin sulfate and heparan sulfate chains in dictat

53 pparent M(r) > 200,000 and are modified with chondroitin sulfate and heparan sulfate chains.

54 e in HSV binding, we tested two native GAGs (chondroitin sulfate and heparan sulfate) and compared ou

55 negatively charged glycosaminoglycans (GAGs) chondroitin sulfate and high-molecular-weight hyaluronan

56 muc bound via the expected binding region to chondroitin sulfate and sulfated hyaluronan but not to t

57 phy, we demonstrate that S. rosetta produces chondroitin sulfate and thus extend the ancestry of this

58 reducing glial scar volume and expression of chondroitin sulfates and the chondroitin sulfate proteog

59 s, hyaluronan, heparan sulfate, heparin, and chondroitin sulfate, and collagen-like peptides as physi

60 f cell-specific GAG chains (heparan sulfate, chondroitin sulfate, and dermatan sulfate) with distinct

61 Our data suggest that IAIP, chondroitin sulfate, and HMW-HA are potential therapeuti

62 e samples to determine GAG (heparan sulfate, chondroitin sulfate, and hyaluronic acid) concentrations

63 ycosaminoglycans (including heparan sulfate, chondroitin sulfate, and hyaluronic acid) lining the vas

64 labeled with a mature neuron marker, NeuN or chondroitin sulfate antibody, NG2.

65 HS and chondroitin sulfate are also essential.

66 nophen, pharmaceutical grade glucosamine and chondroitin sulfate are recommended by ESCEO whereas OAR

67 patients, elevated levels of syndecan-1 and chondroitin sulfate are strongly associated with plasma

68 her affinity for PCV2 than heparin (12 kDa), chondroitin sulfate B (41 kDa), hyaluronic acid (1.6 MDa

69 osahedral capsid to heparan sulfate (HS) and chondroitin sulfate B (CSB) glycosaminoglycans on the ce

70 taches to cells via heparan sulfate (HS) and chondroitin sulfate B (CSB) glycosaminoglycans; however,

71 based synthetic thermogelling macromer and a chondroitin sulfate-based biological network was leverag

72 The chondroitin sulfate-bearing proteoglycans, also known as

73 h antibodies HS4C3 (anti-HS) or IO3H10 (anti-chondroitin sulfate), binding was absent, as occurred wh

74 biopsies for C4S, CD44 variant 7 (CD44v7), a chondroitin sulfate-binding isoform causally implicated

75 an expanded role for this transporter beyond chondroitin sulfate biosynthesis to a variety of importa

76 that both enzymes play a significant role in chondroitin sulfate breakdown.

77 The complex is covalently held together by chondroitin sulfate but during inflammation IalphaI may

78 stV-1) suggest a minor role in infection for chondroitin sulfate but not heparin.

79 9 readily infected cells that express excess chondroitin sulfate but that are devoid of heparan sulfa

80 at both HYAL1 and beta-hexosaminidase cleave chondroitin sulfate, but it is a preferred substrate for

81 ted how divalent cations in concert with the chondroitin sulfate chain influence the structure and st

82 The chondroitin sulfate chain interacted with all protein co

83 chain 2, and bikunin covalently joined by a chondroitin sulfate chain originating at Ser-10 of bikun

84 ch has two heavy chains (HC1 and HC2) on its chondroitin sulfate chain.

85 Binding involves the chondroitin sulfate chains and a specific site on the fi

86 ated chondroitin in addition to low-sulfated chondroitin sulfate chains.

87 NE is known to bind to heparan sulfate- and chondroitin sulfate-containing proteoglycans, we treated

88 Versican is a large chondroitin sulfate-containing, hyaluronic acid-binding

89 Glycosaminoglycans such as chondroitin sulfate (CS) and dermatan sulfate (DS) are l

90 ated GAGs have been found in marine sponges, chondroitin sulfate (CS) and heparan sulfate (HS) have b

91 identify different isomeric disaccharides of chondroitin sulfate (CS) and heparan sulfate (HS), which

92 Chondroitin sulfate (CS) and the CS-rich extracellular m

93 collagens, were fabricated with and without chondroitin sulfate (CS) and their ability to stimulate

94 es that SNORC is a type I protein carrying a chondroitin sulfate (CS) attached to serine 44.

95 ulfation pattern) at the reducing end of the chondroitin sulfate (CS) chain of bikunin, or the core p

96 hological amounts of hyaluronic acid (HA) or chondroitin sulfate (CS) did not directly increase indic

97 rotein, VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively expressed in the pl

98 rsican is a large proteoglycan with numerous chondroitin sulfate (CS) glycosaminoglycan (GAG) side ch

99 Heparan sulfate (HS) and chondroitin sulfate (CS) glycosaminoglycans (GAG) are pr

100 The necessity of heparan sulfate (HS) or chondroitin sulfate (CS) glycosaminoglycans (GAGs) for b

101 modify cell surfaces with specific sulfated chondroitin sulfate (CS) glycosaminoglycans using chemic

102 Chondroitin sulfate (CS) has been widely used for medica

103 Chondroitin sulfate (CS) is a polysaccharide consisting

104 Chondroitin sulfate (CS) is a sulfated polysaccharide th

105 Chondroitin sulfate (CS) is an important glycosaminoglyc

106 Chondroitin sulfate (CS) is the most abundant component

107 Chondroitin sulfate (CS) modification of versican is a p

108 olved to bind to the glycosaminoglycan (GAG) chondroitin sulfate (CS) on host cells.

109 PC generation by formation of complexes with chondroitin sulfate (CS) on TM.

110 tive incorporation of N-glycolyl groups into chondroitin sulfate (CS) over other potential glycoconju

111 f glioblastoma (GBM) is linked to changes in chondroitin sulfate (CS) proteoglycan (CSPG)-associated

112 phosphatase zeta (PTP-zeta), a cell surface chondroitin sulfate (CS) proteoglycan, as a novel IL-34

113 Chondroitin sulfate (CS) proteoglycans (CSPGs) are known

114 es of heparan sulfate (HS) proteoglycans and chondroitin sulfate (CS) proteoglycans in the developmen

115 he contributions of hyaluronic acid (HA) and chondroitin sulfate (CS) to glomerular microvascular end

116 (GAG) substrates, dermatan sulfate (DS), and chondroitin sulfate (CS) when the enzyme is taken up int

117 collagenase activity of CatK is promoted by chondroitin sulfate (CS), a sulfated glycosaminoglycan.

118 osaminoglycans (GAGs), heparan sulfate (HS), chondroitin sulfate (CS), and dermatan sulfate (DS).

119 Heparan sulfate (HS), chondroitin sulfate (CS), dermatan sulfate (DS), and HA

120 tion of glycosaminoglycans (GAGs), including chondroitin sulfate (CS), dermatan sulfate (DS), and hep

121 low molecular weight dextran sulfate (LDS), chondroitin sulfate (CS), heparin (HP), hyaluronic acid

122 hat are covalently bound by an ester bond to chondroitin sulfate (CS), which itself is attached to Se

123 r the modular, efficient assembly of various chondroitin sulfate (CS)-based photoaffinity probes was

124 cules and binds to the linear polysaccharide chondroitin sulfate (CS).

125 tions between a specific sulfated epitope on chondroitin sulfate, CS-E, and the neurotrophins, a crit

126 es Otx2 binding to PNNs, and specifically to chondroitin sulfate D and E, with high affinity.

127 decrease in the Stokes radius and a bikunin chondroitin sulfate-dependent increase of the thermodyna

128 Further, we predict the pose of heparin and chondroitin sulfate derivatives bound to the axon guidan

129 Accumulation of chondroitin sulfate derivatives was detected in mice def

130 following order: heparin > heparan sulfate > chondroitin sulfate = dermatan sulfate.

131 Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) glycosamino

132 Chondroitin sulfate/dermatan sulfate (CS/DS) proteoglyca

133 trated that both XylNapOH- and XylNap-primed chondroitin sulfate/dermatan sulfate GAGs derived from H

134 In contrast, neither the chondroitin sulfate/dermatan sulfate nor the heparan sul

135 irst report on cytotoxic effects mediated by chondroitin sulfate/dermatan sulfate.

136 , heparan sulfate and less sulfated forms of chondroitin sulfate did not augment matrilysin activatio

137 od for the detection and quantification of a chondroitin sulfate disaccharide based on FRET, involvin

138 tions as well as patterns of heparan sulfate/chondroitin sulfate disaccharide sulfation.

139 s, including endothelial heparan sulfate and chondroitin sulfate E, but not with neutral or sialylate

140 e, we report the identification of exogenous chondroitin sulfate-E (CS-E) as an inhibitor of specific

141 e demonstrate that a sugar epitope on CSPGs, chondroitin sulfate-E (CS-E), potently inhibits axon gro

142 yaluronic acid, alginates, gelatin, heparin, chondroitin sulfate, etc.) and biodegradable synthetic p

143 Fucosylated chondroitin sulfate (fCS) extracted from the sea cucumbe

144 saccharides, such as heparan sulfates and/or chondroitin sulfates, for initial attachment.

145 eparin, and the semisynthetic fully sulfated chondroitin sulfate, FSCS, through a displacement-based

146 In this study, chondroitin sulfate-g-glycocholic acid-coated and Exendi

147 g, likely via Wnt sequestration, whereas the chondroitin sulfate GAG chains on TbetaRIII promote Wnt3

148 lycans (GAGs) but not to the closely related chondroitin sulfate GAGs.

149 r that exists with or without heparan and/or chondroitin sulfate glycosaminoglycan (GAG) modification

150 Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblas

151 ase ABC (Ch'ase ABC) digestion of inhibitory chondroitin sulfate glycosaminoglycans significantly enh

152 d by free HS chains, whereas closely related chondroitin sulfate had no effect.

153 ng of heparan sulfate, dermatan sulfate, and chondroitin sulfate have been identified as heparin cont

154 lfated GAGs was comparable with oversulfated chondroitin sulfate in activating the contact system.

155 le all strains directly bound to heparin and chondroitin sulfate in enzyme-linked immunosorbent assay

156 neal glycosaminoglycans, keratan sulfate and chondroitin sulfate, in isolation from their core protei

157 dy of known protein partners for heparan and chondroitin sulfate, including fibroblast growth factor

158 l of sialic acid, but not heparan sulfate or chondroitin sulfate, increased AAV9 transduction regardl

159 Furthermore, inclusion of chondroitin sulfate into the fibers enhanced cartilage-s

160 When chondroitin sulfate is added to arabinan-containing cult

161 tissues [N-terminal, C-terminal (57K), and a chondroitin-sulfate-linked N-terminal fragment (DMP1-PG)

162 tudy, the CS-56 antibody, which recognizes a chondroitin sulfate moiety, labeled a subset of adult br

163 e complexes; indeed, for the highly sulfated chondroitin sulfate motifs, CS-E and CS-D, there are no

164 ads to transfer of the heavy chains from the chondroitin sulfate of inter-alpha-inhibitor to hyaluron

165 itin sulfate proteoglycan, sometimes bearing chondroitin sulfate of type E sugar moieties, binding AP

166 chains" (HC1 and HC2) covalently attached to chondroitin sulfate on the bikunin core protein.

167 The grafting of chondroitin sulfate on the surface of the scaffold is ab

168 SG1 did not bind to cells lacking heparan or chondroitin sulfate on their surface, and binding was re

169 confidence interval [CI] = 1.001-1.007) and chondroitin sulfate (OR = 1.157; 95% CI = 1.025-1.307) h

170 detection and quantification of oversulfated chondroitin sulfate (OSCS) and other high charge-density

171 tan sulfate (DS) impurities and oversulfated chondroitin sulfate (OSCS) contaminants, proton NMR spec

172 example, the rapid detection of oversulfated chondroitin sulfate (OSCS) in heparin could prevent reoc

173 Oversulfated chondroitin sulfate (OSCS) is a harmful contaminant in t

174 ification of the contaminant as oversulfated chondroitin sulfate (OSCS) was reported in our earlier r

175 verse effects was identified as oversulfated chondroitin sulfate (OSCS).

176 onse to heparin adulteration by oversulfated chondroitin sulfates (OSCS) that was associated with adv

177 We found that versican, a large chondroitin sulfate PG, promotes collagen fibrillogenesi

178 nstrate that a specific sugar epitope within chondroitin sulfate polysaccharides can direct important

179 rs resembling unmodified heparan sulfate and chondroitin sulfate precursor molecules.

180 cy of a fixed combination of xanthan gum and chondroitin sulfate preservative free on the ocular surf

181 Xanthan gum/chondroitin sulfate preservative free showed similar cli

182 arin, heparan sulfate, dermatan sulfate, and chondroitin sulfates produced simple mass spectra consis

183 4 by its natural ligands, hyaluronic acid or chondroitin sulfate, protected CLL cells from apoptosis,

184 Exosomes derived from chondroitin sulfate proteoglycan (CSPG) 4 type neural pr

185 Fras1 and AMACO interact directly via their chondroitin sulfate proteoglycan (CSPG) and P2 domains.

186 a potent bacterial enzyme that degrades the chondroitin sulfate proteoglycan (CSPG) component of the

187 hod, we found that Windpipe (Wdp) is a novel chondroitin sulfate proteoglycan (CSPG) in Drosophila.

188 We found that the axon growth inhibitor chondroitin sulfate proteoglycan (CSPG) strongly inhibit

189 l nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan (CSPG)-containing struc

190 e proteoglycan versican (VCAN; also known as chondroitin sulfate proteoglycan 2 [CSPG2]).

191 ased apoptosis and impaired proliferation of chondroitin sulfate proteoglycan 4 (also known as neuron

192 egregation of two rare missense mutations in Chondroitin Sulfate Proteoglycan 4 (CSPG4) (c.391G > A [

193 e interaction between TcdB and its receptors chondroitin sulfate proteoglycan 4 (CSPG4) and frizzled

194 Cell surface chondroitin sulfate proteoglycan 4 (CSPG4) is an attract

195 ecursor cells from which they arise, express chondroitin sulfate proteoglycan 4 (NG2/CSPG4).

196 METHODS AND Expression of CSPG4 (chondroitin sulfate proteoglycan 4) was detected in epid

197 onal antibodies specific to cancer biomarker chondroitin sulfate proteoglycan 4, enabling its detecti

198 We also identify Neuroglycan C/Chondroitin sulfate proteoglycan 5 (NGC/CSPG5), a potent

199 or CNS endocannabinoid, in the modulation of chondroitin sulfate proteoglycan accumulation in Theiler

200 The chondroitin sulfate proteoglycan brevican is a major com

201 ndroitinase ABC, an enzyme that degrades the chondroitin sulfate proteoglycan components of PNNs.

202 CNS, modulates neuroinflammation and reduces chondroitin sulfate proteoglycan deposition around demye

203 ion of the core protein of versican, a major chondroitin sulfate proteoglycan important in palatal sh

204 ensitive to inhibition by Nogo protein or by chondroitin sulfate proteoglycan in vitro.

205 , we treated rats with the growth-inhibitory chondroitin sulfate proteoglycan neurocan, the growth-st

206 Cells expressing the purportedly inhibitory chondroitin sulfate proteoglycan NG2 proliferate in the

207 d expression of chondroitin sulfates and the chondroitin sulfate proteoglycan NG2.

208 evious studies have shown that versican is a chondroitin sulfate proteoglycan of the ECM that is prod

209 growth on myelin-associated glycoprotein and chondroitin sulfate proteoglycan substrates.

210 Zebrafish Decorin is a chondroitin sulfate proteoglycan that exhibits a high de

211 e presence of the growth-inhibitory proteins chondroitin sulfate proteoglycan, myelin basic protein,

212 ssing Mfn-2 altered growth cone responses to chondroitin sulfate proteoglycan, netrin-1, and fibronec

213 The upregulation of chondroitin sulfate proteoglycan, sometimes bearing chon

214 It is found that the chondroitin sulfate proteoglycan-4 (CSPG4)-specific CAR

215 eparan sulfate proteoglycan glypican, or the chondroitin sulfate proteoglycan-degrading enzyme chondr

216 Chondroitin sulfate proteoglycan-related abnormalities i

217 ss-reactivity against versican V2 isoform, a chondroitin sulfate proteoglycan.

218 with spots of aggrecan, a growth-inhibitory chondroitin sulfate proteoglycan.

219 rm), and speculate that the higher levels of chondroitin-sulfate proteoglycan (CSPG) in more mature a

220 ich extracellular glycocalyx composed of the chondroitin sulfate-proteoglycan versican bound to a hea

221 the presence of inhibitory molecules, e.g., chondroitin sulfate proteoglycans (CSPG), in the glial s

222 face of infected-erythrocytes, and placental chondroitin sulfate proteoglycans (CSPG).

223 Chondroitin sulfate proteoglycans (CSPGs) accumulate at

224 Chondroitin sulfate proteoglycans (CSPGs) act as barrier

225 environment contains both growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) and growth-pro

226 In the adult mammalian CNS, chondroitin sulfate proteoglycans (CSPGs) and myelin-ass

227 Chondroitin sulfate proteoglycans (CSPGs) are a family o

228 ellular matrix (ECM) proteoglycans, of which chondroitin sulfate proteoglycans (CSPGs) are a major cl

229 Chondroitin sulfate proteoglycans (CSPGs) are a major co

230 Chondroitin sulfate proteoglycans (CSPGs) are among the

231 Chondroitin sulfate proteoglycans (CSPGs) are highly exp

232 Chondroitin sulfate proteoglycans (CSPGs) are important

233 Both the sugar chains and core proteins of chondroitin sulfate proteoglycans (CSPGs) are inhibitory

234 Myelin-associated inhibitors (MAIs) and chondroitin sulfate proteoglycans (CSPGs) are major cont

235 Chondroitin sulfate proteoglycans (CSPGs) are thought to

236 and extracellular matrix molecules including chondroitin sulfate proteoglycans (CSPGs) found within t

237 Chondroitin sulfate proteoglycans (CSPGs) have been repo

238 Chondroitin sulfate proteoglycans (CSPGs) inhibit repair

239 Previous studies demonstrated that chondroitin sulfate proteoglycans (CSPGs) on apical surf

240 Chondroitin sulfate proteoglycans (CSPGs) play a pivotal

241 urportedly one of the most growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) produced after

242 Chondroitin sulfate proteoglycans (CSPGs) represent a ma

243 We found that chondroitin sulfate proteoglycans (CSPGs) were present i

244 Chondroitin sulfate proteoglycans (CSPGs), a main compon

245 trocytes form an astroglial scar and produce chondroitin sulfate proteoglycans (CSPGs), activate micr

246 densation with mislocalized distributions of chondroitin sulfate proteoglycans (CSPGs), aggrecan and

247 godendrocyte myelin glycoprotein (OMgp), and chondroitin sulfate proteoglycans (CSPGs), and a key que

248 ction of chondroitinase-ABC, known to digest chondroitin sulfate proteoglycans (CSPGs), prevented the

249 Chondroitin sulfate proteoglycans (CSPGs), up-regulated

250 ntaining substantial amounts of glycosylated chondroitin sulfate proteoglycans (CSPGs), whereas glyco

251 re an extracellular matrix structure rich in chondroitin sulfate proteoglycans (CSPGs), which prefere

252 ing of the highly upregulated tenascin-C and chondroitin sulfate proteoglycans (CSPGs).

253 receptors that mediate growth inhibition of chondroitin sulfate proteoglycans (CSPGs).

254 the regeneration-inhibiting matrix molecules chondroitin sulfate proteoglycans (CSPGs).

255 tes myelin-associated glycoprotein (MAG) and chondroitin sulfate proteoglycans (CSPGs).

256 Heparan and chondroitin sulfate proteoglycans (HSPGs and CSPGs, resp

257 glycoprotein--or reactive astrocyte-produced chondroitin sulfate proteoglycans activates PARP1, resul

258 r subsequent plating, the hyaluronan-binding chondroitin sulfate proteoglycans aggrecan, neurocan, an

259 e chondroitinase (Chase) degrades inhibitory chondroitin sulfate proteoglycans and improves axonal sp

260 rons and markedly overcame the inhibition by chondroitin sulfate proteoglycans and mature astrocytes

261 ates, including major CNS inhibitors such as chondroitin sulfate proteoglycans and myelin-associated

262 coproteins tenascin-C and tenascin-R and the chondroitin sulfate proteoglycans brevican and neurocan.

263 ies.SIGNIFICANCE STATEMENT The deposition of chondroitin sulfate proteoglycans contributes to the fai

264 lvement of plasma membrane-bound heparan and chondroitin sulfate proteoglycans in cellular uptake of

265 atterns of hyaluronan and hyaluronan-binding chondroitin sulfate proteoglycans in neural stem cells a

266 Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extracellular m

267 nting the formation of PNNs, suggesting that chondroitin sulfate proteoglycans in the PNNs control pl

268 ween our polymers and negatively charged NG2 chondroitin sulfate proteoglycans of the SVZ extracellul

269 that removes CS from its core protein in the chondroitin sulfate proteoglycans or by preventing the f

270 Chondroitin sulfate proteoglycans present in the cardiac

271 reas cyclopamine reduced expression of these chondroitin sulfate proteoglycans that are known to be i

272 NG2 belongs to the family of chondroitin sulfate proteoglycans that are upregulated a

273 nets are composed of lecticans, a family of chondroitin sulfate proteoglycans that includes aggrecan

274 ture neurons as perineuronal nets containing chondroitin sulfate proteoglycans that limit axonal spro

275 unctionally important carbohydrate chains of chondroitin sulfate proteoglycans that participate in re

276 e was no increase in the gene expression of "Chondroitin Sulfate Proteoglycans" (CSPGs') clusters.

277 on of inhibitory molecules (such as Nogo and chondroitin sulfate proteoglycans) or administration of

278 rophic factor (GDNF), but not the removal of chondroitin sulfate proteoglycans, greatly enhanced the

279 Results are shown for chondroitin sulfate proteoglycans, low molecular weight

280 roblast growth factors, WNT/beta-catenin and chondroitin sulfate-related genes.

281 effect of three putative growth inhibitors--chondroitin sulfate, serum albumin, and transferrin--usi

282 the cysteine-rich domain of MRC binds to the chondroitin sulfate side chains of CD44.

283 rface is, at least in part, dependent on its chondroitin sulfate side chains.

284 ely charged heparin, whereas no reduction in chondroitin sulfate storage was observed.

285 exclusive addition of the glycosaminoglycan chondroitin sulfate, suggesting that factors in the alph

286 A chondroitin sulfate-supplemented diet together with D. p

287 Chondroitin sulfate synthase 1 (Chsy1) is one of a famil

288 a subset of proteins (including IgE, Bank1, chondroitin sulfate synthase 2, Cmip, and Fth1) were exc

289 sis have been identified, and the complex of chondroitin sulfate synthase-1 (CSS1)/chondroitin syntha

290 1 (CSS1)/chondroitin synthase-1 (ChSy-1) and chondroitin sulfate synthase-2 (CSS2)/chondroitin polyme

291 cetylglucosamine (O-GlcNAcylation) on HA and chondroitin sulfate synthesis in primary human aortic sm

292 The transesterification transfer of HCs from chondroitin sulfate to HA is mediated by tumor necrosis

293 aminoglycan side chains of either heparin or chondroitin sulfate type, and large amounts of positivel

294 d ratio between proteoglycans of heparin and chondroitin sulfate type, with increased amounts of hepa

295 In contrast, chondroitin sulfate types A, C, D, and E did not stimula

296 dermatan sulfate (DS), apoptotic debris, and chondroitin sulfate types A, C, D, and E.

297 The four nonstimulatory chondroitin sulfate types, which compete for HA binding,

298 faster on the two native GAGs, one of which, chondroitin sulfate, was also characterized by the highe

299 a chondroitin lyase; although its substrate, chondroitin sulfate, was previously thought to be an ani

300 f poly(vinyl alcohol) and the biological cue chondroitin sulfate with fiber dimensions on the nanosca