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1 with spots of aggrecan, a growth-inhibitory chondroitin sulfate proteoglycan.
2 C4S to inhibit IRBC binding to the placental chondroitin sulfate proteoglycan.
3 y developed antibody, 8B3, that recognizes a chondroitin sulfate proteoglycan.
4 rotein encoded by the sequence secreted as a chondroitin sulfate proteoglycan.
5 DBP, suggesting that the protein binds to a chondroitin sulfate proteoglycan.
6 rons, and of biglycan, a small, leucine-rich chondroitin sulfate proteoglycan.
7 growth cones turn to avoid substratum-bound chondroitin sulfate proteoglycan.
8 ich is consistent with the inhibitor being a chondroitin sulfate proteoglycan.
9 ss-reactivity against versican V2 isoform, a chondroitin sulfate proteoglycan.
10 -type (WT) but not SG-/- platelets contained chondroitin sulfate proteoglycans.
11 degrade the local accumulation of inhibitory chondroitin sulfate proteoglycans.
12 ly inhibitory proteoglycan molecules such as chondroitin sulfate proteoglycans.
13 s assessed by incorporation of Na2(35)SO4 in chondroitin sulfate proteoglycans.
14 s was the major core protein of the secreted chondroitin sulfate proteoglycans.
15 proximately 50%, suggesting association with chondroitin sulfate proteoglycans.
17 ased apoptosis and impaired proliferation of chondroitin sulfate proteoglycan 4 (also known as neuron
18 egregation of two rare missense mutations in Chondroitin Sulfate Proteoglycan 4 (CSPG4) (c.391G > A [
19 e interaction between TcdB and its receptors chondroitin sulfate proteoglycan 4 (CSPG4) and frizzled
20 ceptors (FZD1, FZD2 and FZD7) in neurons and chondroitin sulfate proteoglycan 4 (CSPG4) in pericytes.
24 ical analysis, alpha-smooth muscle actin and chondroitin sulfate proteoglycan 4 staining, microsensor
26 onal antibodies specific to cancer biomarker chondroitin sulfate proteoglycan 4, enabling its detecti
27 hydrogel-of CAR-T cells targeting the human chondroitin sulfate proteoglycan 4, polymer nanoparticle
28 ealing only two genes, encoding aggrecan and chondroitin sulfate proteoglycan 4, that were selectivel
31 sent study, we tested whether degradation of chondroitin sulfate proteoglycan, a known inhibitor of a
32 or CNS endocannabinoid, in the modulation of chondroitin sulfate proteoglycan accumulation in Theiler
33 glycoprotein--or reactive astrocyte-produced chondroitin sulfate proteoglycans activates PARP1, resul
37 r subsequent plating, the hyaluronan-binding chondroitin sulfate proteoglycans aggrecan, neurocan, an
40 so resulted in increased immunoreactivity to chondroitin sulfate proteoglycans and a more extensive a
41 an apoE-dependent process that involves both chondroitin sulfate proteoglycans and an alpha(2)M recep
42 e chondroitinase (Chase) degrades inhibitory chondroitin sulfate proteoglycans and improves axonal sp
43 rons and markedly overcame the inhibition by chondroitin sulfate proteoglycans and mature astrocytes
44 ates, including major CNS inhibitors such as chondroitin sulfate proteoglycans and myelin-associated
45 n-induced or revealed inhibitors such as the chondroitin sulfate proteoglycans and the myelin inhibit
46 ini of chains in the biosynthesis pathway of chondroitin sulfate proteoglycans and their modulation i
47 cell adhesion molecule (NCAM), L1, tenascin, chondroitin sulfate proteoglycan, and peanut agglutinin
48 promoting interactions with cell-associated chondroitin sulfate proteoglycans, and by disrupting the
49 percent of proteoglycans on melanocytes are chondroitin sulfate proteoglycans, and the CD44 chondroi
50 FAK) levels and regulate apoptosis through a chondroitin sulfate proteoglycan- and possibly alpha4 in
51 or SOX1; early oligodendroglial markers were chondroitin sulfate proteoglycan antigen and platelet-de
54 the same sulfated molecule, suggesting that chondroitin sulfate proteoglycan binding in this region
55 before drug-treated growth cones contacted a chondroitin sulfate proteoglycan border, they were narro
57 coproteins tenascin-C and tenascin-R and the chondroitin sulfate proteoglycans brevican and neurocan.
59 ates have now been identified, including the chondroitin-sulfate proteoglycans brevican and versican.
60 ate proteoglycans, we show that cell surface chondroitin sulfate proteoglycans can also mediate bindi
61 senchymal (CD10, CD13, and CD90), pericytic (chondroitin sulfate proteoglycan, CD140a, and CD140b), a
64 epidermis suggests that melanoma-associated chondroitin sulfate proteoglycan colocalizes with epider
65 ning for glial fibrillary acidic protein and chondroitin sulfate proteoglycan compared with OEG-only
66 oteoglycan synthesis or removed cell surface chondroitin sulfate proteoglycan completely blocked apoE
67 mAb, scFv 61 immunoprecipitates the >450-kDa chondroitin sulfate proteoglycan component of the HMW-MA
68 ndroitinase ABC, an enzyme that degrades the chondroitin sulfate proteoglycan components of PNNs.
70 ies.SIGNIFICANCE STATEMENT The deposition of chondroitin sulfate proteoglycans contributes to the fai
71 n N-terminal domain similar to the mammalian chondroitin sulfate proteoglycan core protein NG2, a cen
72 he major CNS inhibiting substrates including chondroitin sulfate proteoglycans could inactivate prote
76 on the identification of a cell surface CD44/chondroitin sulfate proteoglycan (CSPG) and alpha 2 beta
77 Fras1 and AMACO interact directly via their chondroitin sulfate proteoglycan (CSPG) and P2 domains.
79 ies have shown that different members of the chondroitin sulfate proteoglycan (CSPG) class of putativ
80 a potent bacterial enzyme that degrades the chondroitin sulfate proteoglycan (CSPG) component of the
81 Monoclonal antibody Cat-315 recognizes a chondroitin sulfate proteoglycan (CSPG) expressed on the
82 Monoclonal antibody Cat-301 recognizes a chondroitin sulfate proteoglycan (CSPG) expressed on the
83 ted that DEX treatment significantly reduced chondroitin sulfate proteoglycan (CSPG) expression 1 wee
85 hod, we found that Windpipe (Wdp) is a novel chondroitin sulfate proteoglycan (CSPG) in Drosophila.
87 s a chemotactic cofactor, and DBP binds to a chondroitin sulfate proteoglycan (CSPG) on neutrophil pl
90 CGRP) to reveal ascending sensory axons, and chondroitin sulfate proteoglycan (CSPG) to assess the di
92 l nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan (CSPG)-containing struc
96 of heparan sulfate proteoglycans (HSPG) and chondroitin sulfate proteoglycans (CSPG) are required fo
97 the presence of inhibitory molecules, e.g., chondroitin sulfate proteoglycans (CSPG), in the glial s
98 th Tbx20 gain of function, the expression of chondroitin sulfate proteoglycans (CSPG), including aggr
100 rm), and speculate that the higher levels of chondroitin-sulfate proteoglycan (CSPG) in more mature a
106 environment contains both growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) and growth-pro
107 t with the glycosaminoglycan portion of both chondroitin sulfate proteoglycans (CSPGs) and heparan su
109 regeneration by inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) and myelin-ass
113 ellular matrix (ECM) proteoglycans, of which chondroitin sulfate proteoglycans (CSPGs) are a major cl
120 Both the sugar chains and core proteins of chondroitin sulfate proteoglycans (CSPGs) are inhibitory
121 Myelin-associated inhibitors (MAIs) and chondroitin sulfate proteoglycans (CSPGs) are major cont
125 ay be affected by upregulation of inhibitory chondroitin sulfate proteoglycans (CSPGs) following vari
126 and extracellular matrix molecules including chondroitin sulfate proteoglycans (CSPGs) found within t
128 avel that SCI-induced upregulation of matrix chondroitin sulfate proteoglycans (CSPGs) impedes neurog
129 ate proteoglycans (HSPGs), the importance of chondroitin sulfate proteoglycans (CSPGs) in modulating
130 4-sulfate (C4S) chains of very low sulfated chondroitin sulfate proteoglycans (CSPGs) in placenta me
131 previously shown that unusually low sulfated chondroitin sulfate proteoglycans (CSPGs) in the intervi
132 per, we reported that unusually low sulfated chondroitin sulfate proteoglycans (CSPGs) in the intervi
134 developing and regenerating nervous system, chondroitin sulfate proteoglycans (CSPGs) inhibit the in
141 e recently shown that unusually low-sulfated chondroitin sulfate proteoglycans (CSPGs) present in the
142 urportedly one of the most growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) produced after
144 n in birds has been attributed to diffusible chondroitin sulfate proteoglycans (CSPGs) secreted by th
145 In this assay, a gradient of inhibitory chondroitin sulfate proteoglycans (CSPGs) stimulates for
146 extracellular matrix molecules laminin-1 and chondroitin sulfate proteoglycans (CSPGs) were determine
150 trocytes form an astroglial scar and produce chondroitin sulfate proteoglycans (CSPGs), activate micr
151 densation with mislocalized distributions of chondroitin sulfate proteoglycans (CSPGs), aggrecan and
152 godendrocyte myelin glycoprotein (OMgp), and chondroitin sulfate proteoglycans (CSPGs), and a key que
153 in-specific member of the lectican family of chondroitin sulfate proteoglycans (CSPGs), may play a ro
154 ction of chondroitinase-ABC, known to digest chondroitin sulfate proteoglycans (CSPGs), prevented the
155 eurons and Golgi neurons and are composed of chondroitin sulfate proteoglycans (CSPGs), tenascin-R (T
156 hibitory activities of myelin components and chondroitin sulfate proteoglycans (CSPGs), the major cla
158 ntaining substantial amounts of glycosylated chondroitin sulfate proteoglycans (CSPGs), whereas glyco
160 re an extracellular matrix structure rich in chondroitin sulfate proteoglycans (CSPGs), which prefere
161 xyuridine (BrdU) are closely associated with chondroitin sulfate proteoglycans (CSPGs), which were id
170 e was no increase in the gene expression of "Chondroitin Sulfate Proteoglycans" (CSPGs') clusters.
171 noprecipitation studies to interact with the chondroitin sulfate proteoglycan decorin in the medium o
172 trix molecules was compared with that of the chondroitin sulfate proteoglycan decorin, revealing an a
173 eparan sulfate proteoglycan glypican, or the chondroitin sulfate proteoglycan-degrading enzyme chondr
174 CNS, modulates neuroinflammation and reduces chondroitin sulfate proteoglycan deposition around demye
177 (alpha-smooth muscle actin, desmin, and NG2 chondroitin sulfate proteoglycan), endothelial cells (CD
178 s directed against NG2, an integral membrane chondroitin sulfate proteoglycan expressed by oligodendr
179 man single-chain Fv molecule that binds to a chondroitin sulfate proteoglycan expressed on the surfac
180 th epidermal stem cells, melanoma-associated chondroitin sulfate proteoglycan expression within the h
182 re we investigated the role of a specialized chondroitin sulfate proteoglycan extracellular matrix, t
183 nut agglutinin-binding components, tenascin, chondroitin sulfate proteoglycans, fibronectin, laminin)
184 similar to aggrecan, a high-molecular-weight chondroitin sulfate proteoglycan found in cartilage.
186 the lesion core and a reduced expression of chondroitin sulfate proteoglycan glycosaminoglycan sidec
187 alysis strongly suggest that cell-associated chondroitin sulfate proteoglycans greatly facilitate inf
188 rophic factor (GDNF), but not the removal of chondroitin sulfate proteoglycans, greatly enhanced the
189 ed antigen (HMW-MAA), also known as melanoma chondroitin sulfate proteoglycan, has been used as a tar
190 ated important roles for heparan sulfate and chondroitin sulfate proteoglycans (HSPGs and CSPGs) in a
191 ration assay, we found that both heparan and chondroitin sulfate proteoglycans (HSPGs and CSPGs, resp
193 of the link protein family), in which other chondroitin sulfate proteoglycans (i.e. versican, brevic
194 ion of the core protein of versican, a major chondroitin sulfate proteoglycan important in palatal sh
196 We now report that type XV collagen is a chondroitin sulfate proteoglycan in human tissues and cu
197 ults indicate an important role of the CSF-1 chondroitin sulfate proteoglycan in in vivo signaling by
198 nding protein)/brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular ma
199 re, we identified neurocan (NCAN) as a major chondroitin sulfate proteoglycan in the mouse SP/IZ.
200 encountered a border between fibronectin and chondroitin sulfate proteoglycan in the presence and abs
203 lvement of plasma membrane-bound heparan and chondroitin sulfate proteoglycans in cellular uptake of
204 the activities of both myelin inhibitors and chondroitin sulfate proteoglycans in inhibiting neurite
205 atterns of hyaluronan and hyaluronan-binding chondroitin sulfate proteoglycans in neural stem cells a
206 We provide evidence for the in vivo role of chondroitin sulfate proteoglycans in Plasmodium falcipar
209 nting the formation of PNNs, suggesting that chondroitin sulfate proteoglycans in the PNNs control pl
210 ndroitinase ABC (ChABC) to cleave inhibitory chondroitin sulfate proteoglycans in the scar matrix.
212 DIMKKTI) that binds to cell surface melanoma chondroitin sulfate proteoglycan, indicating that SG1 re
213 severe glial scar and enhanced expression of chondroitin sulfate proteoglycans, indicative of a more
215 developmentally regulated membrane-spanning chondroitin sulfate proteoglycan is expressed primarily
216 Here we show that NG2, a structurally unique chondroitin sulfate proteoglycan, is a molecular compone
219 for an inhibitory molecule is collagen IX, a chondroitin sulfate proteoglycan made by sclerotome cell
220 results indicate that the core protein of a chondroitin sulfate proteoglycan may also regulate the a
221 rmined by antisense inhibition that melanoma chondroitin sulfate proteoglycan (MCSP) and membrane-typ
224 onoclonal antibody 7.1, which recognizes the chondroitin sulfate proteoglycan molecule NG2, was used
225 y detects the human homologue of the rat NG2 chondroitin sulfate proteoglycan molecule, which has pre
227 e presence of the growth-inhibitory proteins chondroitin sulfate proteoglycan, myelin basic protein,
228 ssing Mfn-2 altered growth cone responses to chondroitin sulfate proteoglycan, netrin-1, and fibronec
230 , we treated rats with the growth-inhibitory chondroitin sulfate proteoglycan neurocan, the growth-st
231 interactions of the nervous tissue-specific chondroitin sulfate proteoglycans neurocan and phosphaca
235 ct populations of glial cells expressing the chondroitin sulfate proteoglycan NG2 have been described
236 Cells expressing the purportedly inhibitory chondroitin sulfate proteoglycan NG2 proliferate in the
237 nteractions of the developmentally regulated chondroitin sulfate proteoglycan NG2 with human plasmino
238 s react with rat neural cells expressing the chondroitin sulfate proteoglycan NG2, which shows 81% ho
243 ssay we have demonstrated that phosphacan, a chondroitin sulfate proteoglycan of nervous tissue that
244 evious studies have shown that versican is a chondroitin sulfate proteoglycan of the ECM that is prod
245 ously that although all antibodies recognize chondroitin sulfate proteoglycans of similar sizes, each
246 ween our polymers and negatively charged NG2 chondroitin sulfate proteoglycans of the SVZ extracellul
247 the neural matrix is the lectican family of chondroitin sulfate proteoglycans, of which brevican is
248 how that CD44H is expressed as a "part-time" chondroitin sulfate proteoglycan on normal cultured mela
249 chains of heparan sulfate, or in some cases chondroitin sulfate, proteoglycans on the cell surface.
250 that removes CS from its core protein in the chondroitin sulfate proteoglycans or by preventing the f
251 on of inhibitory molecules (such as Nogo and chondroitin sulfate proteoglycans) or administration of
252 h inhibitions from CNS myelin and astroglial chondroitin sulfate proteoglycans partially account for
253 and transforming growth factor-beta2, and of chondroitin sulfate proteoglycans participating in the f
254 lular matrix proteins, and also suggest that chondroitin sulfate proteoglycans play an important role
255 minoglycan (CSGAG), suggesting that melanoma chondroitin sulfate proteoglycan plays a role in modulat
258 picans are secreted or cell-associated brain chondroitin sulfate proteoglycans produced by glia cells
259 ersican (a core protein of one of the matrix chondroitin sulfate proteoglycans) promoter is sufficien
260 effects in part by signaling through the NG2/chondroitin sulfate proteoglycan receptor expressed on t
261 IV)1263-1277 was bound by melanoma cell CD44/chondroitin sulfate proteoglycan receptors and not by th
263 ndroitin sulfate proteoglycans, and the CD44 chondroitin sulfate proteoglycan represented 10% of that
264 as used in early studies to identify a novel chondroitin sulfate proteoglycan, secreted by L-2 cells,
267 monoclonal antibody that recognizes a 680-kD chondroitin sulfate proteoglycan similar to aggrecan, a
269 This apoptotic mechanism was mediated by a chondroitin sulfate proteoglycan, since treating cells w
273 ators pleiotrophin, NrCAM, tenascin, and the chondroitin sulfate proteoglycans, suggesting the import
274 identified O-GalNAc glycans were present on chondroitin sulfate proteoglycans termed lecticans, and
281 ciated antigen (HMW-MAA) is a membrane-bound chondroitin sulfate proteoglycan that is variably expres
282 reas cyclopamine reduced expression of these chondroitin sulfate proteoglycans that are known to be i
284 was seen in the case of heparan sulfate and chondroitin sulfate proteoglycans that do not possess a
285 nets are composed of lecticans, a family of chondroitin sulfate proteoglycans that includes aggrecan
286 ture neurons as perineuronal nets containing chondroitin sulfate proteoglycans that limit axonal spro
287 unctionally important carbohydrate chains of chondroitin sulfate proteoglycans that participate in re
290 e neurite outgrowth inhibitory properties of chondroitin sulfate proteoglycans, the major inhibitory
292 ich extracellular glycocalyx composed of the chondroitin sulfate-proteoglycan versican bound to a hea
293 in E2), THBS1 (thrombospondin 1), and CSPG2 (chondroitin sulfate proteoglycan; versican) were down-re
294 how that after contact with substratum-bound chondroitin sulfate proteoglycan, vinblastine- and taxol
295 endent neoepitope immunolabeling showed that chondroitin sulfate proteoglycan was thoroughly degraded
296 heparan sulfate proteoglycans but possessing chondroitin sulfate proteoglycans, we show that cell sur
297 intensely for versican, a large interstitial chondroitin sulfate proteoglycan, whereas the collagen-c
298 ecipitated protein and the core protein of a chondroitin sulfate proteoglycan, which is expressed on