ライフサイエンスコーパス: chordae

1 for off-pump transapical implantation of neo-chordae.

2 V repair with implantation of artificial neo-chordae.

3 ately before and after dividing second-order chordae.

4 e reported mechanical weakness of myxomatous chordae.

5 apsed or flail segment, and 88% for ruptured chordae.

6 ted with lower chordal forces on the primary chordae and the neochordae.

7 The GAG classes elevated in the myxomatous chordae are associated with matrix microstructure and el

8 xtensible than normal valves, and myxomatous chordae are more mechanically compromised than leaflets.

9 of the anterior leaflet second-order "strut" chordae are unknown.

10 vular repair by severing second-order mitral chordae can improve annuloplasty by reducing papillary m

11 Cutting a minimum number of basal chordae can improve coaptation and reduce ischemic MR.

12 ic results of cutting thickened secondary MV chordae combined with a shallow septal muscular resectio

13 ction, demonstrating the importance of these chordae for LV structure and function.

14 Leaflets and chordae from myxomatous valves (n = 41 ULP, 31 BLP) and

15 Chordae from ULP had 62% more GAGs than those from BLP,

16 Myxomatous leaflets and chordae had 3% to 9% more water content and 30% to 150%

17 To the best of our knowledge, the tension of chordae had never been measured previously as precisely,

18 Cutting anterior mitral leaflet second-order chordae has been proposed for repair in ischemic mitral

19 or the first time the tension applied on the chordae implanted in beating human hearts.

20 erimposed fibrous tissue on both leaflet and chordae is likely the result of subsequent abnormal cont

21 Chordal rupture (i.e., missing chordae) occurred in all 37 patients, but finding indivi

22 Neochord repair further decreased primary chordae peak force (0.21+/-0.14 N) to baseline levels (0

23 epair was associated with the lowest primary chordae peak force compared to the remodeling and triang

24 0.83), and was associated with lower primary chordae peak force compared with the remodeling (0.34+/-

25 s (0.30+/-0.15 N; P=0.001) reduced secondary chordae peak force.

26 Cutting second-order chordae resulted in LV systolic dysfunction and neither

27 Cutting the 2 central basal chordae reversed this without prolapse.

28 light risks for cardiac perforations, mitral chordae rupture, and stroke.

29 Male Dorset sheep (n=20) had P2 chordae severed to create the mitral valve prolapse mode

30 Thickened chordae showed endothelial and subendothelial alpha-smoo

31 e volume overload by percutaneously severing chordae tendinae of the mitral apparatus with a bioptome

32 ntric mitral regurgitation usually caused by chordae tendinae rupture or papillary muscle dysfunction

33 ncluded in this TACT (Transapical Artificial Chordae Tendinae) trial.

34 annulus (MA), papillary muscle (PM), and the chordae tendineac, chordal-sparing MVR is popular.

35 les, the fibrous tissue of cardiac valve and chordae tendineae and the course of coronary arteries.

36 he atrioventricular heart valve leaflets and chordae tendineae are composed of diverse cell lineages

37 ve laws for mitral leaflets and two laws for chordae tendineae are selected to study their effects on

38 ion, when an exponential constitutive law of chordae tendineae is used, a lower closure regurgitation

39 ree mitral leaflet constitutive laws and two chordae tendineae laws with experimental data.

40 hordae tendineae; and 2) the absence of many chordae tendineae on the ventricular surfaces of the lea

41 rgitation was initiated by removing targeted chordae tendineae that are attached to specified leaflet

42 nitor cell diversification into leaflets and chordae tendineae that share inductive interactions and

43 produced by previous operation severing the chordae tendineae were examined.

44 ons, starting from the region near where the chordae tendineae were removed and moving away from the

45 The MC implant location closest to where the chordae tendineae were removed showed the least amount o

46 omprises a nitinol dock, which encircles the chordae tendineae, and a balloon-expandable transcathete

47 genes scleraxis and tenascin, present in the chordae tendineae.

48 tic bleeding, and rupture of tricuspid valve chordae tendineae.

49 urfaces of the leaflets and surrounding many chordae tendineae; and 2) the absence of many chordae te

50 lowed real-time measurement and recording of chordae tension, producing original physiological data.

51 Biochemical changes were more pronounced in chordae than in leaflets.

52 f malformations of the papillary muscles and chordae, that can be detected by transthoracic and trans

53 Preservation of chordae to at least 1 mitral valve leaflet decreased ear

54 -pump transapical implantation of artificial chordae to correct MR is technically safe and feasible;

55 let and reattachment of the anterior leaflet chordae to either the anterior annulus (n = 7) or poster

56 ng a limited number of critically positioned chordae to the leaflet base that most restrict closure b

57 for dynamic behaviour of mitral leaflets and chordae under physiological conditions.

58 The strut chordae were encircled with exteriorized wire snares.

59 In 4 patients neo-chordae were not placed for technical and/or patient-spe

60 Both the leaflet and chordae were separated from the superimposed fibrous tis

61 sequent abnormal contact of the leaflets and chordae with one another.

62 Chronic lesions demonstrated preserved chordae without mitral regurgitation.