ライフサイエンスコーパス: chordal

1 embryologic functions of Dkk1: induction of chordal and prechordal mesoderm and specification of hea

2 Chordal ankle stiffness, derived from the torque versus

3 was produced in 10 dogs by disruption of the chordal apparatus.

4 anterior mitral leaflet length, and abnormal chordal attachment to base of anterior mitral leaflet.

5 l long, 4 and 3-chamber views), and abnormal chordal attachment to mid/base of anterior MV.

6 ptal thickness, anterior MV length, abnormal chordal attachment, and bifid PM mobility are associated

7 entration (+, p=0.003), annular diameter and chordal collagen (+, p=0.03), and water concentration an

8 in a direction compatible with the "oblique" chordal configuration, ie, from the anterior PM to the a

9 and then decreased to 0.9+/-0.1 mL/beat with chordal cutting (P<0.0001); this paralleled changes in t

10 us chordal cutting versus trace to mild with chordal cutting alone versus mild to moderate with ring

11 ntrols, 0.5+/-0.08 with both, 1.0+/-0.3 with chordal cutting alone, 2.0+/-0.4 with ring alone; P<0.01

12 Chordal cutting caused global LV dysfunction: E(es) (1.4

13 We examined the efficacy of such chordal cutting in preventing acute IMR.

14 Chordal cutting increased anterior leaflet inflection an

15 Secondary chordal cutting or reimplantation results in significant

16 sized annuloplasty versus isolated bileaflet chordal cutting versus the combined therapy (n=7 each).

17 ntrols but decreased to trace with ring plus chordal cutting versus trace to mild with chordal cuttin

18 nd tenting area 24% smaller in patients with chordal cutting, indicating that MV apparatus had moved

19 Both before and after chordal cutting, ischemia caused: Septal-lateral annular

20 y 108% in controls versus 28% with ring plus chordal cutting, less than with each intervention alone

21 Before chordal cutting, MR increased significantly during ische

22 odynamic data were acquired before and after chordal cutting.

23 Mitral regurgitation was induced by chordal disruption in adult mongrel dogs.

24 e replacement (n = 6), conventional MVR with chordal excision (n = 7), or chordal-sparing MVR with pr

25 Chordal excision during mitral valve replacement (MVR) i

26 The deleterious effects of chordal excision may be due in part to perturbation of r

27 2 neochordae resulted in higher peak primary chordal forces (0.28+/-0.21 N) compared with those using

28 least 4 neochordae was associated with lower chordal forces on the primary chordae and the neochordae

29 No difference in peak primary chordal forces was observed between 4 and 6 neochordae (

30 ting force sensors were implanted to measure chordal forces.

31 subclassified into those undergoing MVR with chordal preservation (group Ia) and those undergoing MVR

32 Chordal preservation at the time of SJMVR may reduce per

33 Compared with OMC, SJMVR without chordal preservation involved a longer pump time (158 +/

34 the early effects of complete versus partial chordal preservation on left ventricular mechanics.

35 Compared with posterior chordal preservation only, complete retention of the sub

36 ber size and that LV afterload may fall when chordal preservation techniques are used in combination

37 ation acutely following MVR with and without chordal preservation.

38 ordal shortening, chordal transposition, and chordal replacement in treating disease of the anterior

39 Chordal replacement with polytetrafluoroethylene sutures

40 r (6 patients) or leaflet calcification (2), chordal rupture (13), leaflet vegetations (11), annular

41 Chordal rupture (i.e., missing chordae) occurred in all

42 to coaptation (P<0.0001), and more frequent chordal rupture (P<0.0001).

43 ly with decreasing AHCWR in patients without chordal rupture (r(2)=0.66, P<0.0001).

44 aflet billowing and increased frequencies of chordal rupture and may be important in the pathogenesis

45 Prevalence of chordal rupture increased progressively with annulus fla

46 , flail leaflet (12), leaflet prolapse (17), chordal shortening (1), and mitral stenosis (1).

47 Segmental chordal shortening analysis performed in group 2 studies

48 n group 2 studies showed that differences in chordal shortening between rest and post-stress were sig

49 e emphasized the safety and effectiveness of chordal shortening, chordal transposition, and chordal r

50 tively randomized to either total or partial chordal-sparing mitral valve replacement.

51 Sham operation and anterior chordal-sparing MVR did not affect regional LV torsion;

52 Posterior chordal-sparing MVR impaired torsion only after calcium

53 lary muscle (PM), and the chordae tendineac, chordal-sparing MVR is popular.

54 the sham procedure or anterior or posterior chordal-sparing MVR procedure (P > or = .10).

55 tional MVR with chordal excision (n = 7), or chordal-sparing MVR with preservation of the posterior l

56 re or anterior MVR; however, after posterior chordal-sparing MVR, theta max fell in the lateral, post

57 ion to undergo either mitral-valve repair or chordal-sparing replacement in order to evaluate efficac

58 commissural diameter may reduce leaflet and chordal stress and is purported to be conserved across m

59 lthough patients who had preservation of all chordal structures also had decreased end-diastolic volu

60 ected between the group with total preserved chordal structures and the mitral repair group in any of

61 those in the group with completely preserved chordal structures had a larger decline in end-diastolic

62 d plaque-like encasement of the leaflets and chordal structures with intact valve architecture.

63 nly, and 11 had complete preservation of all chordal structures.

64 required to cover the orifice as dictated by chordal tethering (r(2)=0.76).

65 ion (group Ia) and those undergoing MVR with chordal transection (group Ib).

66 Chordal transection resulted in reduced left ventricular

67 aflet resection, edge-to-edge MV repair, and chordal transfer.

68 ety and effectiveness of chordal shortening, chordal transposition, and chordal replacement in treati

69 These results indicate that chordal transsection induces an unloading of myocardium

70 Chordal transsection led to enhanced local shortening an

71 Accordingly, we investigated the effect of chordal transsection on left ventricular shape and on th

72 After chordal transsection, outward displacement of the ventri

73 n a depression of ventricular function after chordal transsection; most recent studies have proposed