ライフサイエンスコーパス: chorion

1 ion, is not expressed by cells in the mutant chorion.

2 and lay poorly viable eggs with a defective chorion.

3 which caused the malformation of the amnion/chorion.

4 scent during gestation and do not invade the chorion.

5 ng heart structure as well as a yolk sac and chorion.

6 traembryonic tissues, including yolk sac and chorion.

7 autophagosome formation in pPROM amnion and chorion.

8 s in blood vessels of floating villi and the chorion.

9 containing Nile red are able to traverse the chorion.

10 in chorionic girdle relative to noninvasive chorion.

11 SNC adhered to the surface and inside of the chorion.

12 D), critical for allantoic elongation to the chorion.

13 unusually high thiol levels in the zebrafish chorion.

14 shapen allantois that fails to fuse with the chorion.

15 pic allantois, which failed to fuse with the chorion, a phenotype that leads to subsequent cardiovasc

16 While mouse sperm could not bind to the chorion, a subpopulation successfully located and crosse

17 he lack of SOX2 only becomes critical in the chorion after 7.5 days postcoitum.

18 ing lung airway and vascular development and chorion-allantois fusion during placental development.

19 (1st LBS) become clearly visible through the chorion almost simultaneously.

20 The umbilical cord, chorion, amnion, and villus parenchyma samples were read

21 e DNA copy number along the third chromosome chorion amplicon was quantified during multiple developm

22 e the mcm proteins, DmCdc45 localises to the chorion amplification foci in the follicle cells of the

23 f4 ortholog, Chiffon, which is essential for chorion amplification in Drosophila egg chambers.

24 Our findings suggest that chorion amplification is a model for understanding metaz

25 bolish ORC2 localization and shows premature chorion amplification.

26 hed motor axons, lack of movement within the chorion and abnormal swimming in response to tactile sti

27 in the chorion is required for fusion of the chorion and allantois during placental development.

28 ence to gastrulation-stage primitive streak, chorion and allantois precursors, respectively.

29 ly self-renewing TBPC lines derived from the chorion and alters expression and subcellular localizati

30 have isolated and grown cultures of primary chorion and amnion cells from human cesarean-section pla

31 y (E) 7.5, Irx4 transcripts are found in the chorion and at low levels in a discrete anterior domain

32 companied by lack of allantois fusion to the chorion and increased degeneration and necrosis in neura

33 lous region where EVTs migrate away from the chorion and invade deeply into the decidua.

34 ressed in a subset of trophoblast within the chorion and labyrinth layer of the mouse placenta.

35 eles of the chiffon gene cause thin, fragile chorions and female sterility, and were found to elimina

36 acellular matrices surrounding eggs in fish (chorion) and mammals (zona pellucida [ZP]) regulate game

37 d fetal (amnion epithelial, mesenchymal, and chorion) and maternal (decidua) cells cultured in four c

38 the expansion of the ectoplacental cone and chorion, and endoreduplication in trophoblast giant cell

39 f the visceral yolk sac, the ectoderm of the chorion, and subsequently the labyrinthine trophoblast o

40 tration of activated immune cells toward the chorion are often associated with preterm birth.

41 thway and affects the development of the egg chorion as well as the polarity of the embryo.

42 D45(low)) of fetal origin was present in the chorion at all gestational ages, associated with stromal

43 on-chorion genes, orthologs of which were on chorion bearing scaffolds in 4 ditrysian families.

44 antois of many Smad5 mutants is fused to the chorion, but is not well-elongated.

45 GBS adhered to chorion cell monolayers to a high degree.

46 were capable of transcytosing through intact chorion cell monolayers without disruption of intracellu

47 GBS invaded chorion cells at a high rate in vitro, and invasion was

48 uld be seen within intracellular vacuoles of chorion cells by transmission electron microscopy.

49 uced autophagy-related changes in amnion and chorion cells in vitro, were investigated.

50 Conversely, chorion cells increased progesterone and soluble HLA-G p

51 Thus, the human chorion contains functionally mature hematopoietic stem

52 IGF1 enhanced proliferation of smooth chorion CTBs, a possible explanation for expansion of th

53 sted the hypothesis that inflammation at the chorion-decidua interface (CDI) induces labor by negatin

54 om larp6b single mutant females showed minor chorion defects, but chorions from eggs laid by larp6a;l

55 lymorphonuclear leukocytes in the amnion and chorion define histological chorioamnionitis (HCA), a co

56 red in follicle cells for cell migration and chorion deposition.

57 lecular mechanisms of conditioned media from chorion-derived human MSCs (CH-CM) and placenta-derived

58 However, the roles and mechanisms of human chorion-derived MSCs (CH-MSCs) in cholangiocarcinoma pro

59 is more epitheliochorial in nature with the chorion developing specialized areolae over the openings

60 While CTBs in the villous chorion differentiate into syncytiotrophoblasts, they ta

61 hematopoietic potential of the allantois and chorion does not require their union, indicating that it

62 n also arise in fetal membrane cells (amnion/chorion) due to OS-induced autophagy and epithelial-mese

63 ng embryos but is present in the decidua and chorion early in development.

64 s encode the major protein components of the chorion (eggshell) and are arranged in two clusters in t

65 se study, essential features of the silkmoth chorion (eggshell) are still not fully understood.

66 During Drosophila oogenesis the chorion (eggshell) gene loci are amplified approximately

67 o meet the demand for the rapid synthesis of chorion (eggshell) proteins, Drosophila ovarian follicle

68 localization, we observe that ACE3, a 440-bp chorion element that contains information sufficient to

69 n of zip9(-/-) eggs failed to undergo normal chorion elevation during activation.

70 ggs prior to activation resulted in abnormal chorion elevation similar to that observed in zip9(-/-)

71 arry the Morpholino oligomer (MO) across the chorion, enter the embryo and reach target cells.

72 GBS interactions with the chorion epithelial cell layer shown here correlate well

73 mniocytes and cytotrophoblasts in the amnion-chorion express this protein.

74 fy the zinc finger transcriptional regulator chorion factor 2 (CF2) as a factor functioning alongside

75 is regulated by the transcription activator Chorion factor 2 in flies and in tissue-culture cells.

76 During human pregnancy the chorion (fetal) lines decidua (maternal) creating the fe

77 are required for normal oocyte development, chorion formation and egg activation.

78 During early chorion formation the vitelline membrane appears to act

79 in immunodeficient mice, were present in the chorion from 15-24 weeks gestation, but were absent at t

80 EMT and LC3B staining was compared in the chorion from pPROM versus term not in labor.

81 nt females showed minor chorion defects, but chorions from eggs laid by larp6a;larp6b double mutant f

82 biphasic uptake pattern, suggesting that the chorion functions as an uptake barrier until 48 hpf.

83 ial follicle cells, which begin synchronized chorion gene amplification after three rounds of endocyc

84 tations in Drosophila E2F and DP that affect chorion gene amplification and ORC2 localization in the

85 ion of DNA replication within the context of chorion gene amplification and transcriptional regulatio

86 cells deficient for Chiffon have a defect in chorion gene amplification but still undergo endocycling

87 e-sterile allele of k43 specifically reduces chorion gene amplification in ovarian follicle cells.

88 Chorion gene amplification in the ovaries of Drosophila

89 ecome 16C polyploid and subsequently undergo chorion gene amplification late in oogenesis.

90 ns on chromosomes, and in follicle cells the chorion gene amplification loci are well-studied example

91 mutant follicle cells appeared to carry out chorion gene amplification normally.

92 EP) and recq4(23), which specifically reduce chorion gene amplification of follicle cells by 4-5 fold

93 f2 mutant females display a 50% reduction in chorion gene amplification, and lay poorly viable eggs w

94 emale sterility, and were found to eliminate chorion gene amplification.

95 ypes of DNA replication, endoreplication and chorion gene amplification.

96 he 320 bp ACE3, the approximately 1.2 kb S18 chorion gene and the 840 bp ori-beta.

97 amplification defects over a 14-kb domain in chorion gene cluster suggests that RecQ4 may have a spec

98 nt for amplification of the third chromosome chorion gene cluster, ACE3 and Ori-beta, are directly bo

99 Drosophila ovary follicle cells amplify the chorion gene clusters approximately 80-fold.

100 amplify the chromosomal loci containing the chorion gene clusters up to 60-fold.

101 of the entire genome to amplification of the chorion gene clusters.

102 the construct did not detectably protect the chorion gene DNA replication origin from position effect

103 somal domain permissible for activity of the chorion gene DNA replication origin.

104 loss of Ttk69 in all follicle cells disrupts chorion gene expression and lack of function in dorsal a

105 dest such model systems is the regulation of chorion gene expression during ovarian follicle maturati

106 sporadic thin eggshell phenotype and reduced chorion gene expression.

107 The Drosophila s15 chorion gene is expressed only in the follicular epithel

108 s large foci that localize to the endogenous chorion gene loci and to active transgenic constructs at

109 ion of replication to amplify the Drosophila chorion gene loci in the follicle cells of egg chambers.

110 ification of the Drosophila third chromosome chorion gene locus requires multiple chromosomal element

111 mmarize almost 40 years' worth of studies on chorion gene regulation while-by comparing Bombyx mori a

112 y associations and faster evolution of early chorion genes and transcriptionally active pseudogenes.

113 The Drosophila chorion genes encode the major protein components of the

114 Over-replication of two clusters of chorion genes in Drosophila ovarian follicle cells is es

115 e developed a technique to detect amplifying chorion genes in individual follicle cells using BrdU in

116 We annotated 127 chorion genes in two segments interrupted by a 164 kb re

117 expression throughout choriogenesis of most chorion genes originally categorized as "middle", and ev

118 of specific loci, including two clusters of chorion genes that encode eggshell proteins.

119 ts interrupted by a 164 kb region with 5 non-chorion genes, orthologs of which were on chorion bearin

120 ls to increase the copy number of Drosophila chorion genes, which encode structural components of the

121 cle cells amplify genomic regions containing chorion genes, which facilitate secretion of eggshell pr

122 mental amplification of Drosophila eggshell (chorion) genes [1].

123 tion that control amplification of eggshell (chorion) genes during Drosophila oogenesis.

124 Drosophila amplifies eggshell (chorion) genes in the follicle cells of the ovary to all

125 ults show that Duox-generated H2O2 fuels egg chorion hardening and that this process plays an essenti

126 ion peroxidase (CPO) plays a crucial role in chorion hardening by catalyzing chorion protein cross-li

127 8 h post fertilization (hpf, starting before chorion hardening), 36-84 hpf (starting after chorion ha

128 horion hardening), 36-84 hpf (starting after chorion hardening), and 240-288 hpf (during organogenesi

129 shed is not known, although contact with the chorion has been discounted.

130 In non-Drosophilid insects, the cuticle, chorion, immune response, silk gland, storage proteins,

131 t viral proteins are present in TBPCs of the chorion in cases of symptomatic congenital infection.

132 Tks4 leads sparser vasculature in the fetal chorion in the Tks4-deficient 'nee' mouse strain.

133 suggest that HCMV replicates in TBPCs in the chorion in vivo, interfering with the earliest steps in

134 cytotrophoblasts in vitro and by the amnion-chorion in vivo.

135 rophoblast cell types were identified in the chorion, including proliferating and differentiating UNC

136 ncreased the influx of immune cells into the chorion, indicative of chorionitis.

137 d that the structural integrity of the outer chorion is dependent upon the presence of a vitelline me

138 n opening for sperm passage around which the chorion is formed.

139 Wnt7b expression in the chorion is required for fusion of the chorion and allant

140 Here, we show that the allantois and chorion, isolated prior to the establishment of circulat

141 An egg chorion ligand termed "sperm motility initiation factor"

142 minor alleles had 3-fold greater activity in chorion-like trophoblast cells (BeWo, JEG-3 and HTR-8/SV

143 Site-specific DNA replication at the chorion loci in Drosophila follicle cells leads to exten

144 Gene amplification at the chorion loci in Drosophila ovarian follicle cells is a m

145 on experiments localize both proteins to the chorion loci in vivo.

146 he relative affinities to DNA from the third chorion locus and to random fragments in vitro, and chem

147 A transgenic chorion locus construct containing ACE3 and Ori-beta was

148 For the Drosophila chorion locus, it has been suggested that ORC binding is

149 To determine the precise structure of the chorion locus, we performed extensive EST analysis, cons

150 palates treated: 1 with an allogenic amnion-chorion membrane (ACM) and the other with a collagen dre

151 Human derived composite amnion-chorion membrane (ACM) has been used to facilitate wound

152 are the effectiveness of an allogenic amnion-chorion membrane (ACM) in promoting clinical and histolo

153 owing treatment with dehydrated human amnion chorion membrane (DHACM), subsequent RNA sequencing and

154 ects of DHACM and a lyophilized human amnion/chorion membrane (LHACM).

155 The chorion membrane covered by a modified coronally advance

156 The Chorion membrane covered by a modified coronally advance

157 cells were positive for all proteins whereas chorion membrane cytotrophoblasts exhibited none.

158 placental villous cytotrophoblast cells and chorion membrane extravillous cytotrophoblast cells cont

159 with a modified coronally advanced flap and chorion membrane for root coverage.

160 with a modified coronally advanced flap and Chorion membrane for root coverage.

161 nd Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft D

162 rian membrane perforation repair with amnion-chorion membranes and results obtained from nine cases u

163 d all perforations were repaired with amnion-chorion membranes.

164 rcinomas defined as <=0.2 mm invasion of the chorion (microinvasive; miSCC) or over (SCC).

165 ilarly, placental RNLS was diminished in the chorion of preterm cases of PEC.

166 e data suggest that an MNL infiltrate in the chorion of the membrane roll marks PTD pathways that are

167 ore than 10 MNLs per high-power field in the chorion of the membrane roll, referred to as MNL-CMR, wa

168 s that are most abundant in the cotyledonary chorion of the placentomes.

169 within a cycle, and that specific factors at chorion origins allow them to escape this negative rerep

170 These results suggest that chorion origins are bound by an amplification complex th

171 ion than on developmental amplification from chorion origins.

172 By contrast, the chorion overproliferates, is erratically folded within t

173 Aedes aegypti chorion peroxidase (CPO) plays a crucial role in chorion

174 the effects of severe PE (sPE) on the smooth chorion portion of the fetal membranes.

175 he follicle cells and is required for normal chorion production and dorsal follicle-cell migration.

176 regulate eggshell synthesis suggest that the chorion production and follicle-cell migration defects a

177 Early BMP4 signalling from chorion progenitors is required for proper differentiati

178 of uncommitted ectoplacental cone cells and chorion progenitors.

179 This study shows that chorion properties, lipid content, biotransformation pot

180 ctrometry analysis provided a description of chorion protein composition and revealed significant red

181 cial role in chorion hardening by catalyzing chorion protein cross-linking through dityrosine formati

182 that control amplification of the eggshell (chorion) protein genes.

183 Proteomics analysis identified 99 chorion proteins in the eggshell and micropyle localizat

184 e membrane appears to act as a reservoir for chorion proteins since s36 was found predominantly in th

185 eggshell hardening involves cross-linking of chorion proteins via their tyrosine residues.

186 otype-by-environment interactions, including chorion proteins, proteins regulating meiotic recombinat

187 accumulation profiles, s36 and s18, putative chorion proteins, were similarly distributed throughout

188 d micropyle localization of 1 early and 6 Hc chorion proteins.

189 ant mice, the allantois fails to fuse to the chorion, resulting in a lack of placenta and failure to

190 een maternal and fetal blood, and the smooth chorion (SC) which surrounds more than 70% of the develo

191 variant transcripts appear in human amnion, chorion, skeletal muscle, small intestine, and in cell c

192 opyle and accumulated in the zebrafish inter-chorion space.

193 -intact and reacted sperm found in the inter-chorion space.

194 To meet the demand for rapid chorion synthesis, Drosophila ovary follicle cells ampli

195 er, larp6a mutant females produced eggs with chorions that failed to elevate fully and were fragile.

196 n-type proteins between wild-type and mutant chorions that paralleled the severity of the phenotype.

197 embryonic mesoderm derivatives including the chorion, the allantois, the amnion and a subset of endot

198 e ZP at any site, while fish sperm cross the chorion through a funnel-shaped opening, the micropyle.

199 For this purpose, MSCs were isolated from chorion tissue, and three cholangiocarcinoma cell lines,

200 tribution of the fetal membranes, amnion and chorion, to human embryonic and fetal hematopoiesis.

201 ifically in the outer epithelial cell layer (chorion/trophectoderm) of the placenta.

202 es inflammation at the interface where fetal chorion trophoblast cells interact with maternal decidua

203 This MPS has outer (fetal chorion trophoblast cells) and inner chambers (maternal

204 s used to remove the amniotic epithelium and chorion trophoblastic layer, which resulted in exposing

205 zygotic (MZ) twins (8-19 years old) of known chorion type.

206 expression patterns in 72 samples of amnion, chorion, umbilical cord, and sections of villus parenchy

207 ontains two specialized regions: the villous chorion where gases and nutrients are exchanged between

208 an IMI to zebrafish embryos with and without chorion, while no significant difference was observed be

209 ome localized within distinct regions of the chorion, while others are taken up by the oocyte or beco

210 ile extraembryonic structures, including the chorion, yolk sac blood islands, and allantois appear to