ライフサイエンスコーパス: chorioretinal

1 (AL) amyloidosis with progressive bilateral chorioretinal abnormalities documented with short-wavele

2 A few cases have described chorioretinal abnormalities primarily occurring in elder

3 , such vessels would typically be defined as chorioretinal anastomoses (CRAs); however, continuing st

4 h a highly disorganised retinal vasculature, chorioretinal anastomoses and the persistence of embryon

5 ed restoring venous outflow by 1) creating a chorioretinal anastomosis, 2) administering recombinant

6 eating a laser-induced or surgically induced chorioretinal anastomosis, 2) administering recombinant

7 represented by assessment of the presence of chorioretinal and/or retinal vascular lesions, best-corr

8 igh myopia was staphyloma (23%), followed by chorioretinal atrophy (19.3%).

9 ttled foveal changes (3 patients), extensive chorioretinal atrophy (2 patients), or small yellowish s

10 ithin the PXE subgroups, eyes without CNV or chorioretinal atrophy (Group 1) showed the least reducti

11 ithout choroidal neovascularization (CNV) or chorioretinal atrophy (Group 1); eyes with active or fib

12 ndus; 95% CI, 1.13-5.45; P = 0.02) or patchy chorioretinal atrophy (HR, 3.17 vs. tessellated fundus;

13 macular degeneration and progressive bifocal chorioretinal atrophy (MCDR1/PBCRA; telomeric).

14 Chorioretinal atrophy after subretinal VN for RPE65-medi

15 from 14 patients across 5 centers developed chorioretinal atrophy after subretinal VN.

16 N injection developed progressive perifoveal chorioretinal atrophy after surgery.

17 the congenital ocular defects of Sveinsson's chorioretinal atrophy and congenital retinal coloboma.

18 d with concurrent development of progressive chorioretinal atrophy and hyperpigmented deposits in the

19 al length, and presence of diffuse or patchy chorioretinal atrophy and lacquer cracks.

20 Most common reported toxicities were chorioretinal atrophy and vascular occlusions.

21 Severe disease presented with widespread chorioretinal atrophy as shown by SW-FAF and spectral-do

22 in FST did not correlate with development of chorioretinal atrophy at 12 months.

23 racterized by a childhood-onset, progressive chorioretinal atrophy confined to the posterior pole.

24 ed to decrease in size, and moderate macular chorioretinal atrophy developed.

25 e corticosteroid treatment, complete macular chorioretinal atrophy followed.

26 ime of iMFC/PIC lesion regression and patchy chorioretinal atrophy formation were contrast-enhanced,

27 atients were identified as having perifoveal chorioretinal atrophy if (1) the areas of atrophy were n

28 ere focal pigment mottling of the retina and chorioretinal atrophy in 11 of the 17 eyes with abnormal

29 We observed new chorioretinal atrophy in 50% of the treated eyes.

30 e appearance and quantify the growth rate of chorioretinal atrophy in patients who received voretigen

31 o probands had a retinal fold in one eye and chorioretinal atrophy in the other; the other 2 had bila

32 Staphyloma and chorioretinal atrophy increased in prevalence with incre

33 Staphyloma and chorioretinal atrophy lesions were the most common fundu

34 Fundus examination revealed chorioretinal atrophy of the posterior pole contiguous w

35 ive or fibrotic CNV (Group 2); and eyes with chorioretinal atrophy only (Group 3).

36 FP vs 545 eyes [6.9%] by UWFI; P < .001) and chorioretinal atrophy or scarring by 116% (50 eyes [0.6%

37 malities being focal pigmentary mottling and chorioretinal atrophy or scarring.

38 nced type 2 and 3 retinopathy presented with chorioretinal atrophy that typically started in the peri

39 We report a case in which diffuse chorioretinal atrophy was developed at the injection sit

40 (21%) had grade 3 disease in which profound chorioretinal atrophy was present outside the fovea.

41 Discrete areas of punched-out chorioretinal atrophy were observed in 4 (26.7%) eyes.

42 ary atrophy were common while staphyloma and chorioretinal atrophy were rare, pathologic myopia appea

43 In 4 eyes, well-delineated macular chorioretinal atrophy with a hyperpigmented ring develop

44 indings were focal macular pigment mottling, chorioretinal atrophy with a predilection for the macula

45 However, adverse events (e.g., chorioretinal atrophy) have been reported in many patien

46 Funduscopy revealed circular areas of chorioretinal atrophy, and FAF imaging showed sharply de

47 aphyloma, lacquer cracks, Fuchs spot, myopic chorioretinal atrophy, and myopic choroidal neovasculari

48 were older than 50 years and showed profound chorioretinal atrophy, as well as coarse hyperpigmented

49 nd group 2 consisted of 33 eyes with diffuse chorioretinal atrophy, but not to the extent of patchy c

50 Peripapillary chorioretinal atrophy, central retinal thickness, and su

51 This later evolved to chorioretinal atrophy, most marked in the mid-peripheral

52 All eyes presented with diffuse chorioretinal atrophy, which resembles pathologic myopic

53 re identified as having developed perifoveal chorioretinal atrophy.

54 nt epithelium and circular pigmented area of chorioretinal atrophy.

55 ge may represent a specific cause leading to chorioretinal atrophy.

56 institutions and demonstrated posterior-pole chorioretinal atrophy.

57 orrelated with the development of VN-related chorioretinal atrophy.

58 ons, pavingstone-like changes, and pigmented chorioretinal atrophy.

59 There was no evidence of chorioretinal atrophy.

60 retinal degeneration, resulting in profound chorioretinal atrophy.

61 s, which progressed to the eventual profound chorioretinal atrophy.

62 abnormalities, as well as atypical bilateral chorioretinal atrophy.

63 nal atrophy, but not to the extent of patchy chorioretinal atrophy.

64 ssion were enlargement of diffuse and patchy chorioretinal atrophy; a new pathology was present in 8

65 Both groups displayed similar structural chorioretinal biomarkers and systemic hemodynamic findin

66 ding 1 case diagnosed through histology from chorioretinal biopsy and another case associated with a

67 Chorioretinal biopsy confirmed the diagnosis of ECD in 1

68 dertaken of all patients that have undergone chorioretinal biopsy for suspected lymphoma at Moorfield

69 Chorioretinal biopsy provided a definitive diagnosis of

70 production of neurotrophic agents, improved chorioretinal blood circulation, and inhibition of proin

71 segment and lens dysgenesis, retinal folds, chorioretinal coloboma, and Peters anomaly.

72 with bilateral microphthalmia and bilateral chorioretinal coloboma.

73 uch as ptosis, hypertelorism, nystagmus, and chorioretinal coloboma.

74 ercentage of lesions demonstrating excessive chorioretinal damage without CNV formation.

75 The most common colobomatous anomaly was a chorioretinal defect present in 109 eyes (71.2%).

76 (GA) of the choroid and retina is a blinding chorioretinal degeneration caused by deficiency of ornit

77 by ornithine accumulation and a progressive chorioretinal degeneration of unknown pathogenesis.

78 ies for choroideremia, an X-linked recessive chorioretinal degeneration, demand a better understandin

79 f choroideremia (CHM), an X-linked inherited chorioretinal degenerative disease leading to blindness,

80 polarized protein secretion in AMD and other chorioretinal degenerative disorders.

81 c CNV were posterior uveitis or inflammatory chorioretinal disease (19.4%), myopia (18.4%), hereditar

82 , 80.5 years) without evidence or history of chorioretinal disease and from nine donors with AMD (age

83 Assessment of chorioretinal disease is dependent on the ability to vis

84 t1 mutant mice develop a rapidly progressing chorioretinal disease that begins with photoreceptor deg

85 central serous chorioretinopathy (cCSC) is a chorioretinal disease with unknown disease etiology.

86 common causes being idiopathic, inflammatory chorioretinal disease, and myopia.

87 armacotherapies in diagnosing and monitoring chorioretinal disease.

88 photography screening in the near future for chorioretinal disease.

89 tection of subtle microstructural changes in chorioretinal diseases by improving imaging of the choro

90 T will be added to photography screening for chorioretinal diseases in the near future.

91 Unrelated chorioretinal diseases were diagnosed in the affected ey

92 es of 32 patients with or without any ocular chorioretinal diseases were enrolled prospectively.

93 es to be a beneficial tool for evaluation of chorioretinal diseases.

94 lutionized the pharmacological management of chorioretinal diseases.

95 nically viable strategy for the treatment of chorioretinal diseases.

96 ther define this new technology's utility in chorioretinal diseases.

97 the clinician's ability to assess and manage chorioretinal diseases.

98 te-dot syndromes are a heterogenous group of chorioretinal disorders that have many common clinical f

99 may be used in the treatment of a variety of chorioretinal disorders.

100 ng-acting drug delivery for the treatment of chorioretinal disorders.

101 ified to cause microcephaly, lymphedema, and chorioretinal dysplasia (MLCRD) as well as chorioretinal

102 ized by variable combinations of lymphedema, chorioretinal dysplasia, microcephaly and/or mental reta

103 d chorioretinal dysplasia (MLCRD) as well as chorioretinal dysplasia, microcephaly, and mental retard

104 volume and eye developmental anomalies with chorioretinal dysplasia.

105 nd lymphedema from a microcephaly-lymphedema-chorioretinal-dysplasia cohort.

106 Choroideremia (CHM) is a monogenic X-linked chorioretinal dystrophy affecting the photoreceptors, re

107 were normal in PRPH2-related central areolar chorioretinal dystrophy but increased in PRPH2-related S

108 Choroideremia (CHM) is an X-linked chorioretinal dystrophy that is caused by mutations with

109 typical RP starting in the second decade to chorioretinal dystrophy with a later age of onset.

110 Choroideremia (CHM) is an x-linked recessive chorioretinal dystrophy, with 30% caused by nonsense mut

111 Migration of the chorioretinal EC line Rf/6a and a primary culture of hum

112 The chorioretinal findings were characterized with spectral-

113 systemic infections related to IDU may have chorioretinal findings.

114 Chorioretinal fold (CFs) is a rare condition resulting f

115 respectively): subretinal fluid (SRF; 30,9), chorioretinal folds (30,68), macular exudate (ME; 20,5),

116 his was only 1 of 4 astronauts to experience chorioretinal folds approaching the fovea.

117 imary contributing factor for development of chorioretinal folds during spaceflight is unknown.

118 Chorioretinal folds were observed in 12 of 72 eyes (17%;

119 ociated with IIH include CNVM, ME, SRF, VSR, chorioretinal folds, choroidal infarction, and BRAO.

120 ed the scans for the qualitative presence of chorioretinal folds.

121 th systemic inflammation, immune regulation, chorioretinal gene expression, and diet.

122 ite-centered hemorrhage in 9 of 96 patients, chorioretinal infiltrate in 8 of 96 patients, endophthal

123 ents with endophthalmitis; the others showed chorioretinal infiltrates or intraretinal or white-cente

124 olution of her symptoms and remission of the chorioretinal infiltrates.

125 In the NNUMS group, a high chorioretinal involvement rate (94.1%) and delayed diagn

126 Vitreous or chorioretinal involvement was identified in 16 of 96 pat

127 hic representation and thickness database of chorioretinal layers in normal macula were generated.

128 le-resistant Aspergillosis that demonstrated chorioretinal lesion growth despite intravitreal amphote

129 l condition characterized by an oval-shaped, chorioretinal lesion in the temporal macula of unknown e

130 er analysis prioritized clinical criteria of chorioretinal lesion location and intraocular inflammati

131 n = 6 [12%]), optic disc edema (n = 3 [6%]), chorioretinal lesions (n = 2 [4%]), vitritis (n = 1 [2%]

132 testing and was suspected to be the cause of chorioretinal lesions after other viral and infectious c

133 The appearance of the chorioretinal lesions as white to pinkish, round, non-el

134 After three months, chorioretinal lesions decreased and vision recovered.

135 In 6 weeks, the chorioretinal lesions had healed and visual acuity had i

136 may be insufficient to arrest progression of chorioretinal lesions in some cases.

137 lving, placoid, or multifocal nonnecrotizing chorioretinal lesions may be a feature of active Zika vi

138 virus and that share analogous features with chorioretinal lesions reported in cases of Dengue fever

139 ant imaging studies and clinical features of chorioretinal lesions that are presumably associated wit

140 bretinal, confluent, placoid, and multifocal chorioretinal lesions.

141 mmation levels, and by the size reduction in chorioretinal lesions.

142 ly hypofluorescence and late staining of the chorioretinal lesions.

143 Chorioretinal M. chimaera lesions should motivate high s

144 optical sectioning of the vasculature called chorioretinal optical sectioning (CROS).

145 ndpoint encompassing new active inflammatory chorioretinal or inflammatory retinal vascular lesions,

146 Three-dimensional mapping of chorioretinal oxygen tension allowed quantitative P(O2)

147 Three-dimensional chorioretinal P(O2) maps were generated in rat eyes unde

148 Relative to eyes lacking detectable chorioretinal pathologic features, eyes with any patholo

149 ted visual acuity of 20/20 or better with no chorioretinal pathology.

150 phakic patients and may be mistaken for true chorioretinal pathology.

151 bility of SFCT measurements in patients with chorioretinal pathology.

152 Peripheral chorioretinal pigment abnormalities were also observed.

153 myopia (18.4%), hereditary dystrophy (5.4%), chorioretinal scar (4.2%), choroidal rupture (3.5%), opt

154 en in the OCT images relate to the excavated chorioretinal scar observed clinically.

155 child had torpedo maculopathy, 1 child had a chorioretinal scar with iris and lens coloboma, and 1 ch

156 th iris and lens coloboma, and 1 child had a chorioretinal scar.

157 proximal to a hyperpigmented and/or atrophic chorioretinal scar.

158 ritis, branch retinal artery occlusions, and chorioretinal scarring in a case of intrauterine transmi

159 Chorioretinal scarring was present in 3 patients (7%).

160 chiae (P < 0.002), vitritis (P < 0.005), and chorioretinal scars (P < 0.02).

161 vement); and either (3) punched-out atrophic chorioretinal scars or (4) more than minimal mild anteri

162 Chorioretinal scars with pigment accumulations developed

163 be aware of atypical eye findings, including chorioretinal scars.

164 for MEWDS included: 1) multifocal gray-white chorioretinal spots with foveal granularity; 2) characte

165 crystalline lens, aberrant vitreous density, chorioretinal thickening, and foreign body/air presence.

166 Chorioretinal thinning in CKD is associated with a lower

167 sified into 4 stages of activity: choroidal, chorioretinal, transitional, and resolved.

168 values of the retinal VA, VDI and TNEP, and chorioretinal VA, VDI and L in males.

169 With a lower fraction of inspired oxygen, chorioretinal vascular P(O2) and mean arteriovenous P(O2

170 Light flicker-induced changes in the chorioretinal vasculature P(O2) and arteriovenous P(O2)

171 Measurement of changes in the chorioretinal vasculature P(O2) can potentially advance

172 d our ability to assess the integrity of the chorioretinal vasculature.

173 nsional mapping of oxygen tension (P(O2)) in chorioretinal vasculatures.

174 A recent report has suggested that chorioretinal venous anastomosis can be achieved in some