ライフサイエンスコーパス: chromosomal abnormality

1 myelodysplastic syndrome (MDS), with the 5q- chromosomal abnormality.

2 ssion bias often indicates the presence of a chromosomal abnormality.

3 to an infant with Down's syndrome or another chromosomal abnormality.

4 tion of HPCs that were JAK2V617F(+) or had a chromosomal abnormality.

5 lap between IGH@-t, CRLF2-d, and established chromosomal abnormalities.

6 eading to centrosome amplification and gross chromosomal abnormalities.

7 ate and 83 patients (3.4%) with adverse-risk chromosomal abnormalities.

8 with phenotypes observed in individuals with chromosomal abnormalities.

9 st common ones were hematologic diseases and chromosomal abnormalities.

10 ng patients with either normal karyotypes or chromosomal abnormalities.

11 lls manage to divide in the context of gross chromosomal abnormalities.

12 expressed oncomirs not previously linked to chromosomal abnormalities.

13 s a signature for CLL patients with specific chromosomal abnormalities.

14 haracterized by an increase in the number of chromosomal abnormalities.

15 an arise from single-gene defects as well as chromosomal abnormalities.

16 results in defective spindles that generate chromosomal abnormalities.

17 to IR-induced apoptosis and several types of chromosomal abnormalities.

18 defined factors does not induce, or require, chromosomal abnormalities.

19 rized by the presence of specific, recurrent chromosomal abnormalities.

20 enetically heterogeneous, displaying diverse chromosomal abnormalities.

21 ly characterized by numerical and structural chromosomal abnormalities.

22 oligo-FISH was used to characterize diverse chromosomal abnormalities.

23 21 were compared to test for potential fetal chromosomal abnormalities.

24 s, predisposing to TCRalpha locus-associated chromosomal abnormalities.

25 ypes in 17 subjects with apparently balanced chromosomal abnormalities.

26 and increased frequencies of thymocytes with chromosomal abnormalities.

27 reported to be associated with one of these chromosomal abnormalities.

28 tive checkpoint responses and high levels of chromosomal abnormalities.

29 samples that harbor one of several selected chromosomal abnormalities.

30 of meiotic metaphase in the face of massive chromosomal abnormalities.

31 transmission of dysfunctional telomeres and chromosomal abnormalities.

32 id cytogenetics; the others had a variety of chromosomal abnormalities.

33 ients and seldom showed consistent nonrandom chromosomal abnormalities.

34 crosatellite instability nor multiple, major chromosomal abnormalities.

35 often acquire large structural and numerical chromosomal abnormalities.

36 evels of basal and mitomycin C (MMC)-induced chromosomal abnormalities.

37 y 10 to 20% of stillbirths are attributed to chromosomal abnormalities.

38 ial aggregation, and association of CDH with chromosomal abnormalities.

39 n and continued to proliferate, accumulating chromosomal abnormalities.

40 as atm mutant seeds germinate with extensive chromosomal abnormalities.

41 e entry, irrespective of TP53 alterations or chromosomal abnormalities.

42 ses an increase in endogenous DNA damage and chromosomal abnormalities.

43 ocious resumption of meiosis and spindle and chromosomal abnormalities.

44 f of RAP80 has been linked to an increase in chromosomal abnormalities.

45 or detecting genomic structural variants and chromosomal abnormalities.

46 er and induce double-strand breaks (DSB) and chromosomal abnormalities.

47 400 population doublings without exhibiting chromosomal abnormalities.

48 ult of its strong association with number of chromosomal abnormalities.

49 The chromosomal abnormalities 1q21, 5p15/5q35, 9q34, 13q14.3

50 of 45 Htx copy number variations were large chromosomal abnormalities, 38 smaller copy number variat

51 nd B-other ALL, that is, lacking established chromosomal abnormalities (5.6%; 43 of 772 B-other cases

52 patients who had cytogenetically documented chromosomal abnormalities (5q-, 7-, +8, 17-, or 20-).

53 Clonal cytogenetic evolution with additional chromosomal abnormalities (ACAs) in chronic myelogenous

54 Additional chromosomal abnormalities (ACAs) in Philadelphia-positiv

55 with CCA/Ph(-) and those without additional chromosomal abnormalities (ACAs).

56 Chromosomal abnormalities account for the most commonly

57 wever, the molecular mechanism through which chromosomal abnormalities affect the pathogenesis and ou

58 tability (CIN) in tumors is characterized by chromosomal abnormalities and an altered gene expression

59 a significantly increased frequency of gross chromosomal abnormalities and an S-phase-specific accumu

60 Cells with reduced levels of BAP1 exhibit chromosomal abnormalities and decreased DNA repair by ho

61 eletion of mouse Hus1 results in spontaneous chromosomal abnormalities and embryonic lethality.

62 enomic instability in human cells, including chromosomal abnormalities and hyperrecombination.

63 overlapping phenotypes including spontaneous chromosomal abnormalities and increased cancer predispos

64 We and others have demonstrated chromosomal abnormalities and increased DNA damage in PA

65 It is widely accepted that both large-scale chromosomal abnormalities and mutation of specific genes

66 The combination of nonrandom chromosomal abnormalities and other types of genetic alt

67 c abnormalities in leukemia cells (including chromosomal abnormalities and patterns of gene expressio

68 SNP-A analysis allows enhanced detection of chromosomal abnormalities and provides important prognos

69 h of noscapine exposure at 20 muM elucidated chromosomal abnormalities and the inability of chromosom

70 Ultimately, this generates chromosomal abnormalities and the release of nuclear DNA

71 ostic algorithm including gene mutations and chromosomal abnormalities and their changes during clona

72 ata describing the age-specific incidence of chromosomal abnormalities and their prognostic relevance

73 tients display extensive and varied forms of chromosomal abnormalities and this genomic instability i

74 val, and overall survival associated with 21 chromosomal abnormalities and three cytogenetic risk gro

75 ive ductal lesions to accumulate progressive chromosomal abnormalities and to develop toward the stag

76 embryonic fibroblasts exhibited spontaneous chromosomal abnormalities and underwent premature senesc

77 en patients (9%) did not have any detectable chromosomal abnormality and 6 (4%) could not be classifi

78 ession in AML+8 patients with +8 as the sole chromosomal abnormality and AML-CN patients.

79 mal translocation is the most common form of chromosomal abnormality and is often associated with con

80 way; this is sufficient to inhibit oncogenic chromosomal abnormality and suppress tumorigenesis.

81 mester findings of ultrasonographic markers, chromosomal abnormalities, and clinical outcomes for a w

82 ential regions of linkage and two associated chromosomal abnormalities, and evidence is accumulating

83 is common among aneuploid mice used to study chromosomal abnormalities, and male germline transmissio

84 f congenital malformations, deformities, and chromosomal abnormalities, and mental and behavioural di

85 s can expand clonally, accumulate additional chromosomal abnormalities, and progress to cancer.

86 ential regions of linkage and two associated chromosomal abnormalities, and the evidence is accumulat

87 r kg, P < 0.001), year of birth (P < 0.001), chromosomal abnormalities (aOR: 3.83, P < 0.01), longer

88 remarkable for the extent to which the same chromosomal abnormalities are detected in individual tum

89 Using metaphase cytogenetics (MC), chromosomal abnormalities are found in only a proportion

90 Our data demonstrate that widespread chromosomal abnormalities are frequent in lung adenocarc

91 Chromosomal abnormalities are frequent in myeloid malign

92 Chromosomal abnormalities are frequently caused by probl

93 Chromosomal abnormalities are important for the classifi

94 ase spreads, and wider applications to other chromosomal abnormalities are in development.

95 Chromosomal abnormalities are increasingly used to risk

96 tgrowth of cellular variants with additional chromosomal abnormalities are major causes of disease pr

97 s been mapped to chromosome band 3p25, where chromosomal abnormalities are observed in a variety of h

98 ly screening T-DNA lines for the presence of chromosomal abnormalities are presented and discussed.

99 nical associations for more than 20 specific chromosomal abnormalities are presented.

100 Although it is known that gross chromosomal abnormalities are remarkably common in early

101 At least 12 structural chromosomal abnormalities are shared between T24, TSU-Pr

102 Individual chromosomal abnormalities are strong independent indicat

103 a heritable developmental disorder in which chromosomal abnormalities are thought to play a role.

104 Nonrandom recurrent chromosomal abnormalities are ubiquitous in multiple mye

105 typically distinct, share the same oncogenic chromosomal abnormalities as well as immunoglobulin heav

106 of the MLL gene located at 11q23 are common chromosomal abnormalities associated with acute leukemia

107 The t(8;21) is one of the most frequent chromosomal abnormalities associated with acute myeloid

108 However, because of the extensive chromosomal abnormalities associated with CIN, its cause

109 that there are mitotic as well as nonmitotic chromosomal abnormalities associated with loss of conden

110 row and peripheral blood of 25 patients with chromosomal abnormalities associated with MDS (monosomy

111 rom the identification of the first specific chromosomal abnormality associated with cancer to the de

112 Aneuploidy, the most common chromosomal abnormality at birth and the main ascertaine

113 Balanced chromosomal abnormalities (BCAs) represent a relatively

114 as copy-number variants (CNVs), but balanced chromosomal abnormalities (BCAs) still require karyotypi

115 espite the clinical significance of balanced chromosomal abnormalities (BCAs), their characterization

116 that edited bacterial cells did not harbour chromosomal abnormalities but demonstrated elevated glob

117 n Rag2(-/-) Atm(-/-) mice contained multiple chromosomal abnormalities, but none of these involved th

118 Detection of specific chromosomal abnormalities by FISH and metaphase cytogene

119 We, therefore, examined chromosomal abnormalities by high-resolution single nucl

120 nce that ATM and ATR prevent accumulation of chromosomal abnormalities by promoting Mre11/Rad50/Nbs1

121 the International Staging System (ISS) with chromosomal abnormalities (CA) detected by interphase fl

122 is poorly understood, there is evidence that chromosomal abnormalities can arise through an alteratio

123 The development of chromosomal abnormalities (CAs) in the Philadelphia chro

124 G depletion causes DNA double-strand breaks, chromosomal abnormalities, cell-cycle delays, defective

125 tin integrity, gene mutations, and numerical chromosomal abnormalities], characterizes the relationsh

126 h the disease but having a variety of nearby chromosomal abnormalities, collectively described as cis

127 No patient presented with chromosomal abnormalities commonly seen in secondary leu

128 sease, neuromuscular disease, liver disease, chromosomal abnormalities, congenital immunodeficiencies

129 ma-IR), and cells from these animals exhibit chromosomal abnormalities consistent with defects in DNA

130 Chromosomal abnormalities contribute substantially to re

131 ns, p53 mutation, or the presence of various chromosomal abnormalities corresponds to variability of

132 A number of specific chromosomal abnormalities define the subgroups of multip

133 Chromosomal abnormalities detected by FISH at study entr

134 rrow plasma cell infiltration, with t(11;14) chromosomal abnormality detected by fluorescence in situ

135 mmediately before karyotyping for a possible chromosomal abnormality detected by maternal age and fet

136 n monosomy 7 cells to determine whether this chromosomal abnormality developed de novo or arose as a

137 The presence or absence of other concurrent chromosomal abnormalities did not affect survival in the

138 Most notably, the severe chromosomal abnormality did not cause cell death owing t

139 Telomere dysfunction may result in chromosomal abnormalities, DNA damage responses, and eve

140 CA1-PALB2 interaction show greatly increased chromosomal abnormalities due apparently to combined def

141 e functionally important for accumulation of chromosomal abnormalities during disease progression in

142 rs in a variety of human cancers and induces chromosomal abnormalities during mitosis associated with

143 these carried copy number variations and/or chromosomal abnormalities, emphasizing the importance of

144 Chromosomal abnormalities, especially t(4;14) and del(17

145 Genetically unmodified MSCs can undergo chromosomal abnormalities even at early passages and for

146 f the regions coincided with areas of common chromosomal abnormalities frequently observed in CLL.

147 This chromosomal abnormality fuses part of the AML1/RUNX1 gen

148 opoietic stem cells (HSC) is associated with chromosomal abnormalities, genomic instability, and HSC

149 Use of free fetal DNA to diagnose fetal chromosomal abnormalities has been hindered by the inabi

150 Several nonrandom chromosomal abnormalities have been associated with neur

151 e past five decades, a plethora of nonrandom chromosomal abnormalities have been consistently reporte

152 ion whole-genome sequencing, many consistent chromosomal abnormalities have been described together w

153 ges in telomere functions and the associated chromosomal abnormalities have been implicated in human

154 Chromosomal abnormalities have long been proposed to pla

155 has been an increasing number of reports of chromosomal abnormalities identified by subtelomeric flu

156 ty to either known tumor suppressor genes or chromosomal abnormalities identified in previous cytogen

157 Chromosomal abnormalities, immunoglobulin heavy chain va

158 An analysis of chromosomal abnormalities in 10 head and neck cancer cel

159 77 of 1,090 couples (98.8%) and detected 127 chromosomal abnormalities in 11.7% (126/1,077) of couple

160 Low-pass GS revealed additional chromosomal abnormalities in 50 (4.0%) couples, includin

161 tudy, we analyzed the prognostic value of 12 chromosomal abnormalities in a series of 354 MM patients

162 -wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA o

163 outcomes associated with distinct high-risk chromosomal abnormalities in acute myeloid leukemia (AML

164 elogenous leukemia (CML), the development of chromosomal abnormalities in addition to the Philadelphi

165 compared the genome-wide distribution of the chromosomal abnormalities in both sexes.

166 one of the mechanisms by which 53BP1 causes chromosomal abnormalities in Brca1-deficient cells.

167 Chromosomal abnormalities in childhood acute lymphoblast

168 Compared with other chromosomal abnormalities in CML, patients with 3q26.2 r

169 Events causing chromosomal abnormalities in ESCs may be related to even

170 These changes included de novo chromosomal abnormalities in five of the 26 patients (19

171 Common recurrent chromosomal abnormalities in FL included gains of 2, 5,

172 rognostic implications of the most recurrent chromosomal abnormalities in human B-cell chronic lympho

173 le-chromosome aneuploidies, we show that sub-chromosomal abnormalities in human blastocysts arise fro

174 togenetic tool to define the contribution of chromosomal abnormalities in human diseases.

175 V6 on band 12p13 are amongst the most common chromosomal abnormalities in human leukemia.

176 In addition, its removal by chromosomal abnormalities in humans could cause split ha

177 in carcinomas recapitulate the discovery of chromosomal abnormalities in leukemias and sarcomas deca

178 Two additional perineurioma cases had large chromosomal abnormalities in multiple chromosomes, inclu

179 e the prognostic implications of overlapping chromosomal abnormalities in multiple myeloma (MM), demo

180 nuclear oncoprotein deregulated by recurring chromosomal abnormalities in myelodysplastic syndrome (M

181 lerated or blastic phase or developed clonal chromosomal abnormalities in Ph+ cells or BCR-ABL mutati

182 for CML who were subsequently found to have chromosomal abnormalities in Ph-negative cells.

183 with chronic myeloid leukemia (CML) develop chromosomal abnormalities in Philadelphia chromosome (Ph

184 Clonal chromosomal abnormalities in Philadelphia chromosome-neg

185 ith radioimmunotherapy may identify existing chromosomal abnormalities in previously treated patients

186 enerate DNA strand breakage as we have found chromosomal abnormalities in Rad1-depleted cells.

187 her investigated the role of larger CNVs and chromosomal abnormalities in RDD and performed associati

188 nical doses of etoposide on the induction of chromosomal abnormalities in spermatocytes and their tra

189 the basis of both the frequent occurrence of chromosomal abnormalities in that region and numerous su

190 The accumulation of chromosomal abnormalities in the absence of proper telom

191 The genetic dissection of hot spots for chromosomal abnormalities in the age of the sequenced hu

192 The long latency (234-299 days) and clonal chromosomal abnormalities in the AMLs suggest that addit

193 creening is targeted toward the detection of chromosomal abnormalities in the fetus(1,2).

194 s profound DNA damage, resulting in striking chromosomal abnormalities in the form of chromatid or ch

195 y that could not be accounted for by visible chromosomal abnormalities in the karyotype.

196 review the current literature on diagnosing chromosomal abnormalities in the pre-implantation embryo

197 e true prognostic significance of individual chromosomal abnormalities in this age group remains uncl

198 the development of autoimmunity as they age: Chromosomal abnormalities in top3beta(-/-) mice might le

199 duction in the number of HPCs that contained chromosomal abnormalities in two JAK2V617F-negative IM p

200 ultiple genomic regions) is a major cause of chromosomal abnormalities in uterine leiomyomas; we prop

201 A recurrent chromosomal abnormality in acute myeloid leukemia is the

202 The most common chromosomal abnormality in human cancer is the reciproca

203 RUNX1) fusion product and is the most common chromosomal abnormality in pediatric leukemia.

204 1)(p13;q22) translocation is the most common chromosomal abnormality in pediatric leukemia.

205 Importantly, the father possesses the same chromosomal abnormality in the absence of ASD, indicatin

206 tal heart disease even in the absence of any chromosomal abnormality in the newborn.

207 TIC), to identify significant ciliochoroidal chromosomal abnormalities including chromosome-arm-sized

208 Chromosomal abnormalities including the GLI3 locus were

209 ble-stranded DNA breaks (DSBs) can result in chromosomal abnormalities, including deletions, transloc

210 Chromosomal abnormalities, including homozygous deletion

211 Human myeloid leukemias are characterized by chromosomal abnormalities, including translocations, del

212 These data support the proposal that chromosomal abnormalities, including translocations, wit

213 t the Bcl-xl/Myc tumors contain a variety of chromosomal abnormalities, including trisomies, transloc

214 ntegrity and cause the accumulation of gross chromosomal abnormalities-including rearrangements, dele

215 ICUS patients carried a somatic mutation or chromosomal abnormality indicative of clonal hematopoies

216 isorder (ASD) in association with a balanced chromosomal abnormality involving 2p16.3.

217 Accumulation of DNA damage, mutations, and chromosomal abnormalities is associated with aging in ma

218 which includes both numerical and structural chromosomal abnormalities, is a hallmark of cancer.

219 Among singleton pregnancies without chromosomal abnormalities lasting >/=20 weeks in Denmark

220 One such patient had a complex chromosomal abnormality, leading to the identification o

221 Chromosomal abnormalities may arise during germ cell and

222 ultiple myeloma (MM), risk stratification by chromosomal abnormalities may enable a more rational sel

223 Chromosomal abnormalities (namely 13q, 17p, and 11q dele

224 t(8;21) is one of the most frequent chromosomal abnormalities observed in acute myeloid leuk

225 rome is one of the most common and penetrant chromosomal abnormalities observed in individuals with a

226 reased both the numerical and the structural chromosomal abnormalities observed.

227 hromosome 1 (1p) is the second most frequent chromosomal abnormality observed in these tumors.

228 fragile site stability, because spontaneous chromosomal abnormalities occurred preferentially at com

229 To determine whether these chromosomal abnormalities occurred randomly or at specif

230 The chromosomal abnormalities of 14q32 are often associated

231 Genetic studies of IMTs have demonstrated chromosomal abnormalities of 2p23 and rearrangement of t

232 Heterogeneity of chromosomal abnormalities of chromosomes 1, 3, 6, and 8

233 MBL cells bear the same chromosomal abnormalities of chronic lymphocytic leukemi

234 otype of viable hybrids and the incidence of chromosomal abnormalities of dead hybrid embryos were de

235 w protrusions, and carried the mutations and chromosomal abnormalities of neoplastic clones.

236 o increase the likelihood of gaining certain chromosomal abnormalities of the kind thought to lead to

237 The most common chromosomal abnormality of infant acute lymphoblastic le

238 sible for this observation and the impact of chromosomal abnormalities on aging.

239 ffymetrix 10K array, we identified a somatic chromosomal abnormality on chromosome 7p in one HH tissu

240 d patterns of gene expression correlate with chromosomal abnormalities or assess expression of genes

241 s (class I mutations) acting in concert with chromosomal abnormalities or gene mutations that block d

242 subtypes that are characterized by specific chromosomal abnormalities or gene mutations.

243 ogical conditions, typically associated with chromosomal abnormalities or mutations in a single gene.

244 mortality included noncardiac structural or chromosomal abnormalities (OR, 3.2; 95% CI, 1.3-7.9), us

245 14)(q24.1;q32), complex karyotype (5 or more chromosomal abnormalities), or low hypodiploidy/near tri

246 ns, CD38 and ZAP-70 expression, or any other chromosomal abnormality other than 17p deletion, in whic

247 nificantly increased the diagnostic yield of chromosomal abnormalities per couple (11.7%) in comparis

248 ata revealed that, in addition to leading to chromosomal abnormalities, RAD51D-deficiency resulted in

249 Chromosomal abnormalities resulting in tumor suppressor

250 e formation of multiple mitotic spindles and chromosomal abnormalities, results in defects in cytokin

251 NA MMR loss may ultimately lead to the gross chromosomal abnormalities seen in t-AML.

252 lomere-based crisis to generate the types of chromosomal abnormalities seen in the earliest lesions o

253 s included 159 congenital malformations, six chromosomal abnormalities, seven stillbirths, and nine n

254 As a variety of diseases are linked to such chromosomal abnormalities, SNP chips promise new insight

255 tumor genetic heterogeneity in neuroblastoma.Chromosomal abnormalities such as 11q deletion are assoc

256 Patients having chromosomal abnormalities such as 11q deletion, trisomy

257 transformed cells often contain a variety of chromosomal abnormalities such as euploidy, translocatio

258 In BS cells, chromosomal abnormalities such as sister chromatid excha

259 Chromosomal abnormalities, such as deletions and duplica

260 tain lymphoid malignancies exhibit recurrent chromosomal abnormalities, such as translocations and de

261 1-null embryos contain increased spontaneous chromosomal abnormalities, suggesting that loss of Hus1

262 Many human chromosomal abnormality syndromes include specific cogni

263 prior cardiothoracic operation, prematurity, chromosomal abnormalities, syndromes, noncardiac congeni

264 es were studied together, we found that each chromosomal abnormality (TEL/AML1, BCR/ABL, or MLL abnor

265 ncer exhibits significantly higher levels of chromosomal abnormalities than sporadic breast cancers.

266 of sarcomas seem to be defined by consistent chromosomal abnormalities that can be detected using a v

267 Our findings suggest that chromosomal abnormalities that disrupt the function of t

268 polymorphism array to identify the secondary chromosomal abnormalities that drive the development of

269 yo, as well as fetal alcohol syndrome (FAS), chromosomal abnormalities that include trisomies 18 and

270 Chromosomal abnormalities that likely arise from recombi

271 In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infer

272 marrow failure, AML, MDS and complex random chromosomal abnormalities that the single-mutant mice do

273 er nearly 40 years of the recognition of the chromosomal abnormality that defines CML, specific thera

274 The Philadelphia chromosome, a chromosomal abnormality that encodes BCR-ABL1, is the de

275 BRCA2 exhibit radiation hypersensitivity and chromosomal abnormalities, thus revealing a potential ro

276 leted genes, subordinately, with established chromosomal abnormalities to derive a 2-tier genetic cla

277 emia (CML) since the recognition of a common chromosomal abnormality to the introduction of ever more

278 emature chromatid separation (PCS) and gross chromosomal abnormalities typical of genomic instability

279 DNA end resection, which increases NHEJ and chromosomal abnormalities, ultimately causing mitotic ca

280 The incidence of most chromosomal abnormalities varied significantly with age.

281 e intelligence quotient of survivors without chromosomal abnormalities was 79.7 (16.6) with 25% below

282 screen for loss of heterozygosity (LOH) and chromosomal abnormalities was performed with parallel an

283 These chromosomal abnormalities were acquired somatic mutation

284 Two chromosomal abnormalities were associated with a signifi

285 ines were studied alone, we found that these chromosomal abnormalities were associated with the predo

286 onged hypoglycemia, congenital anomalies, or chromosomal abnormalities were excluded from the study.

287 No chromosomal abnormalities were found.

288 cancer and while the number and size of the chromosomal abnormalities were greatly reduced in cells

289 Transient chromosomal abnormalities were infrequent.

290 BRCA2 defects are associated with chromosomal abnormalities, which is a hallmark of genomi

291 These cryptic chromosomal abnormalities, which seem to be nonrandom, h

292 AML), isolated trisomy 13 (AML+13) is a rare chromosomal abnormality whose prognostic relevance is po

293 latform for interrogating the interaction of chromosomal abnormalities with mutations.

294 tion (inv dup) markers, the largest group of chromosomal abnormalities with neocentromere formation,

295 correlated genomic lesion load and specific chromosomal abnormalities with patient survival.

296 cute myeloid leukemia (N = 20) for recurrent chromosomal abnormalities with the use of routine cytoge

297 Overall, 83% of cases have chromosomal abnormalities, with a median of three abnorm

298 , we discovered that arsenic exposure causes chromosomal abnormalities, with a preponderance of end-t

299 ata provide evidence that the development of chromosomal abnormalities within GLI3 is associated with

300 sion of HRAS(V12) increases the frequency of chromosomal abnormalities within one or two cell cycles,