ライフサイエンスコーパス: chromosomal mutation

1 osomal DNA (Hfr formation) does not underlie chromosomal mutation.

2 n of metabolite overproduction from specific chromosomal mutations.

3 of mitochondrial and nuclear DNA damage and chromosomal mutations.

4 rray-based gene mapping to identification of chromosomal mutations.

5 t progress, even in the presence of multiple chromosomal mutations.

6 oratory conditions was seen only due to rare chromosomal mutations.

7 pered by the inability to introduce specific chromosomal mutations.

8 tuberculosis is exclusively a consequence of chromosomal mutations.

9 strategies designed against ABR mediated by chromosomal mutations.

10 multifactorial and mainly due to spontaneous chromosomal mutations.

11 ithin the same facility mimic the effects of chromosomal mutations.

12 that can be used in gene mapping studies and chromosomal mutation analysis projects.

13 described so far emerge as a consequence of chromosomal mutations and cannot be leveraged to tackle

14 or a panel of known resistance determinants (chromosomal mutations and genes carried on plasmids).

15 prisingly, P. aeruginosa variants with these chromosomal mutations as well as a pslG deletion mutant

16 Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via ho

17 This chromosomal mutation causes a 25-fold increase in the le

18 on mutations for their ability to complement chromosomal mutations defective in each activity.

19 lyzed for antimicrobial resistance genes and chromosomal mutations, extra-chromosomal plasmids, and m

20 fication, mapping, and characterization of a chromosomal mutation, faa (for function affecting Alp),

21 In the absence of the selecting drugs, chromosomal mutations for resistance to antibiotics and

22 mutants were able to resolve closely spaced chromosomal mutations, identify deletions and rearrangem

23 on either selection of an R. prowazekii rpoB chromosomal mutation imparting rifampin resistance or ex

24 We describe an assay for chromosomal mutation in cells carrying the F' lac.

25 A chromosomal mutation in exbB2 also failed to exhibit a d

26 nas syringae pv. tomato DC3000 strain with a chromosomal mutation in the AvrPtoB C-terminus elicited

27 sing the flow cell method, we found that the chromosomal mutation in the rbf gene delayed biofilm for

28 Strain BM108 of Escherichia coli has a chromosomal mutation in the rpmB,G operon that prevents

29 In addition, a V. cholerae strain with a chromosomal mutation in vibA was constructed by marker e

30 ate reductase (DHFR) by introducing D27G,N,F chromosomal mutations in a key catalytic residue with su

31 transport, but a V. cholerae strain that had chromosomal mutations in both the exbB1 and exbB2 genes

32 When chromosomal mutations in exbB1 or exbD1 were introduced

33 t of four single and six multiple Ala-to-Gly chromosomal mutations in the A16xAxAxA22 motif on the ca

34 horough study of several clinically observed chromosomal mutations in the enzyme at the cellular, bio

35 esistance is increasing in Salmonella due to chromosomal mutations in the quinolone resistance-determ

36 efflux pumps, followed by the development of chromosomal mutations in time, which together lead to hi

37 We show that the chromosomal mutation is recombination protein- and pol I

38 Gene inactivation of pRB through chromosomal mutations is one of the principal reasons fo

39 Antibiotic resistance arising via chromosomal mutations is typically specific to a particu

40 remaining eight ORFs, nonpolar gene-specific chromosomal mutations located in each of these ORFs were

41 Chromosomal mutation of P1 did not affect the expression

42 Chromosomal mutation of this sequence, termed HSE1, eras

43 n cells and the effects of various bacterial chromosomal mutations on the efficiency of transfer in v

44 reflect an ancient genetic event, such as a chromosomal mutation, perhaps involving variation in oth

45 0(-9) to 0.6 x 10(-9) per site per year, a Y chromosomal mutation rate of 0.7 x 10(-9) to 0.9 x 10(-9

46 tated by strong fertility selection and high chromosomal mutation rates.

47 Although classically attributed to chromosomal mutations, resistance is most commonly assoc

48 ne repair precisely targets and corrects the chromosomal mutation responsible for a genetic and/or ac

49 On the basis of individual chromosomal mutations, risk for metastasis was increased

50 el porin, OmpG, is produced in response to a chromosomal mutation termed cog-192.

51 Guided by this structure, we generated a chromosomal mutation that abolishes Gsk regulation by pp

52 t Saccharomyces cerevisiae was isolated as a chromosomal mutation that increased the efficiency of -1

53 ch of these mutants has a single, recessive, chromosomal mutation that inhibits accumulation of posit

54 equencing to better characterize spontaneous chromosomal mutations that alter two pathogenicity pheno

55 l mismatch repair mechanisms and correct the chromosomal mutation to wild type.

56 enomic delivery system for the correction of chromosomal mutations was designed by incorporating two

57 netic determinants of antibiotic resistance, chromosomal mutations were identified in CHC155 (rdxA, g