ライフサイエンスコーパス: chromosomal stability

1 accumulation of R-loops at CEN chromatin for chromosomal stability.

2 ty of chromosome alignment, segregation, and chromosomal stability.

3 r-suppressive functions in part by promoting chromosomal stability.

4 ew histones for chromatin assembly to ensure chromosomal stability.

5 levels, mitotic checkpoint proficiency, and chromosomal stability.

6 ing promoting proper spindle orientation and chromosomal stability.

7 es where it mediates mitotic progression and chromosomal stability.

8 as a regulator of the mitotic checkpoint and chromosomal stability.

9 MSH3 suppresses tumorigenesis by maintaining chromosomal stability.

10 played comparable levels of HDR function and chromosomal stability.

11 ial for mitotic integrity and maintenance of chromosomal stability.

12 ir critical role in telomere maintenance and chromosomal stability.

13 ating a transcriptional program that governs chromosomal stability.

14 nous mutant alleles of STAG2 led to enhanced chromosomal stability.

15 ation therapy resistance, and maintenance of chromosomal stability.

16 lines; however, the absence of p27 affected chromosomal stability.

17 Telomeres must be capped to preserve chromosomal stability.

18 ete regions of the genome and contributes to chromosomal stability.

19 volved in regulating genome surveillance and chromosomal stability.

20 t the end of linear chromosomes that promote chromosomal stability.

21 hat a nuclear pool of PTEN helps to maintain chromosomal stability.

22 es and play a key role in the maintenance of chromosomal stability.

23 terminal DNA sequence repeats that maintain chromosomal stability.

24 trol and is essential for the maintenance of chromosomal stability.

25 ing gene silencing, life span extension, and chromosomal stability.

26 ing gene silencing, life-span extension, and chromosomal stability.

27 or through its caretaker role in maintaining chromosomal stability.

28 lation during mitosis which is essential for chromosomal stability.

29 h each round of DNA replication and maintain chromosomal stability.

30 ell nucleus, required for the maintenance of chromosomal stability.

31 ibits LOH induction, possibly by maintaining chromosomal stability.

32 o important for mitotic spindle assembly and chromosomal stability.

33 es, serves to preserve genomic integrity and chromosomal stability.

34 uring mitosis and also helps to maintain the chromosomal stability.

35 lomerase to maintain telomeres that regulate chromosomal stability and cellular mitosis.

36 ine whether p21 was required for maintaining chromosomal stability and delaying tumor onset.

37 of eukaryotic chromosomes, are required for chromosomal stability and integrity.

38 GC-1alpha function maintains female germline chromosomal stability and its proper segregation during

39 a novel role for Cebpd in the maintenance of chromosomal stability and suggest a potential tumor supp

40 ry in preventing mislocalization of Cse4 for chromosomal stability and suggest that oncohistone H3 mu

41 lays an essential role in the maintenance of chromosomal stability and that loss of PTEN leads to mas

42 tumor cells requires this enzyme to maintain chromosomal stability and to counteract the cellular mit

43 abolism are essential for the maintenance of chromosomal stability and tumor suppression.

44 amily, has been implicated in maintenance of chromosomal stability and tumour suppression.

45 clude histone deacetylation, gene silencing, chromosomal stability, and aging.

46 tion, TCAF1 is required for fork protection, chromosomal stability, and cell survival after replicati

47 rily associated with RNA and DNA metabolism, chromosomal stability, and cell-cycle regulation.

48 functions including cell-cycle progression, chromosomal stability, and cellular response to therapeu

49 ndent checkpoint control and preservation of chromosomal stability, and cooperated with apoptosis in

50 They regulate DNA repair and recombination, chromosomal stability, and gene transcription, and most

51 cally distinctive-nearly always benign, with chromosomal stability, and originating from the medial s

52 eak repair (DSBR) through DNA end resection, chromosomal stability, and tumor suppression, indicating

53 t plays pivotal roles in genomic imprinting, chromosomal stability, apoptosis, and aging.

54 Their prominent roles in chromosomal stability are demonstrated by the linkage of

55 They further establish maintenance of chromosomal stability as one of the additional tumor-sup

56 that Chfr is a tumor suppressor and ensures chromosomal stability by controlling the expression leve

57 llite instability, were further analysed for chromosomal stability by karyotyping.

58 man topoisomerase I plays a critical role in chromosomal stability by relaxing the DNA superhelical t

59 ologous recombination repair (HRR) maintains chromosomal stability by the repair of DNA double-strand

60 ialized Fe-S cluster helicase that preserves chromosomal stability by unwinding unimolecular G4 DNA l

61 tant insight as to how centrosome number and chromosomal stability can be affected by the E3 ligase t

62 stem cells (SSCs), which exhibited superior chromosomal stability compared with embryonic stem cells

63 lear movement and positioning, karyogamy and chromosomal stability, defects also found in the bikDelt

64 The results suggest that chromosomal stability depends upon a complex interaction

65 ependent checkpoint mechanism contributes to chromosomal stability, DNA damage responses, and tumor s

66 anconi anemia (FA) ensure the maintenance of chromosomal stability during DNA replication.

67 However, chromosomal stability during extended passaging cannot b

68 The FA pathway maintains chromosomal stability in concert with replication fork m

69 repair genes play a dual role in maintaining chromosomal stability in mammalian cells, the known role

70 uring cell division is important to maintain chromosomal stability in order to prevent cancer and bir

71 ortant for maintaining spindle integrity and chromosomal stability, in part by virtue of its ability

72 odification that can alter gene activity and chromosomal stability, influencing both differentiation

73 ional roles in suppression of recombination, chromosomal stability, metabolic regulation, meiosis, an

74 We compared the chromosomal stability of over 500 neural cell samples fr

75 To examine the chromosomal stability of repetitions of the trinucleotid

76 rmine if p53 gene status correlated with the chromosomal stability of the RER cancers.

77 hesis of tumorigenesis suggests that loss of chromosomal stability or maintenance functions results i

78 as Rb and p53, and its ability to influence chromosomal stability, potential mechanisms of JCV T-ant

79 at telomeres and that proper maintenance of chromosomal stability requires both POT proteins.

80 hagic tumor suppressor, plays a dual role in chromosomal stability, surprisingly independent of autop

81 or has been implicated in the maintenance of chromosomal stability through a function in DNA repair.

82 P-E is thus essential for the maintenance of chromosomal stability through efficient stabilization of

83 otic checkpoint and that CHK2 contributes to chromosomal stability through hMps1.

84 or has been implicated in the maintenance of chromosomal stability through homology-directed repair o

85 cer susceptibility protein, BRCA2, preserves chromosomal stability through roles in the repair of DNA

86 Telomerase maintains cell viability and chromosomal stability through the addition of telomere r

87 ays a fundamental role in the maintenance of chromosomal stability through the physical interaction w

88 nine ICLs was sought; both cell survival and chromosomal stability were adversely affected in pol kap

89 involved in cell cycle, DNA replication, and chromosomal stability were consistently elevated in the