ライフサイエンスコーパス: chromosome 4

1 and 2 NZB loci (Nba1 and Lbw2/Sbw2, both on chromosome 4).

2 day junctions or their precursors in meiotic chromosomes(4).

3 ssociations with PD, including cg06690548 on chromosome 4.

4 nteny between macaque chromosome 5 and human chromosome 4.

5 argely clustered in two main locations along chromosome 4.

6 and used to guide a sequence analysis along chromosome 4.

7 rms, NHA1 and NHA2, found in tandem on human chromosome 4.

8 3.2 Mb region at the upper end of sunflower chromosome 4.

9 The il14 gene is located on chromosome 4.

10 haps unrelated to the Gimap5 mutation on rat chromosome 4.

11 n related genes located within 150 Kb on rat chromosome 4.

12 predicted 3-exon gene of unknown function on chromosome 4.

13 ayed microsatellite loci flanking dhfr along chromosome 4.

14 ed no introns in the zn-16 coding regions on chromosome 4.

15 tolerance and adiposity, which was linked to chromosome 4.

16 protein-coding genes and 778 pseudogenes on chromosome 4.

17 regions are on human chromosome 9 and mouse chromosome 4.

18 ied near a major quantitative trait locus on chromosome 4.

19 sub-telomeric deletions in the short arm of chromosome 4.

20 genes and ESTs within the wdl locus on mouse chromosome 4.

21 n both the maternal and paternally inherited chromosome 4.

22 es were mapped to different regions of mouse chromosome 4.

23 TS2 has previously been mapped at 14.3 cM on chromosome 4.

24 idence for a chromosomal copy of the rDNA on chromosome 4.

25 family of highly related genes clustered on chromosome 4.

26 me 14, and a locus for migraine with aura on chromosome 4.

27 encoding the small heterodimer partner 1, on chromosome 4.

28 an 85 kb tandem triplication on distal mouse chromosome 4.

29 ) was previously mapped to a region on mouse chromosome 4.

30 mma GH gene are located between A3 and A5 on chromosome 4.

31 to a >35 centimorgan (cM) interval of murine chromosome 4.

32 ated traits such as pod number, localized to chromosome 4.

33 gosity (LOH) of other chromosomes, including chromosome 4.

34 nt of the VC-induced tumors displayed LOH on chromosome 4.

35 requency of mortal hybrids following MMCT of chromosome 4.

36 a complex R-like gene cluster on Arabidopsis chromosome 4.

37 kage (NPL) score, 1.80, at marker D4S2367 on chromosome 4.

38 R-like gene At4g16890 from a gene cluster on Chromosome 4.

39 he Ram1 locus to a distal 7.1 cM interval on chromosome 4.

40 ted Xo1, that maps to a 1.09 Mbp fragment on chromosome 4.

41 ation resulting in loss of heterozygosity on chromosome 4.

42 et attain nominal significance, and only for chromosome 4.

43 analysis with the syntenic region from human chromosome 4.

44 called AUXIN-RESISTANT6 (AXR6) which maps to chromosome 4.

45 2, whereas active rRNA genes map to NOR4, on chromosome 4.

46 at least in part, by the NOD Idd9 region on chromosome 4.

47 er (ZF) gene 2610305D13Rik located on distal chromosome 4.

48 background that primarily undergoes loss of chromosome 4.

49 ressor gene TET2 in MDS patients with UPD on chromosome 4.

50 All usual combinations of trisomies (chromosomes 4, 10, 17, 18) were significant favorable fa

51 any major heterotrophic clade consists of a chromosome (4,109,442 base pairs) and megaplasmid (491,6

52 opacity at 24 months were detected on mouse chromosomes 4, 11, and 12.

53 cations between the Ig heavy chain (IgH) and chromosomes 4, 11, and 16, translocations involving Ig l

54 trait loci (QTL) associated with EAU on rat chromosomes 4, 12, and 10 (Eau1, Eau2, and Eau3).

55 rring translocations were also identified on chromosomes 4D, 12F, and 16C.

56 hree other intronless pseudogenes of Rac1 on chromosomes 4, 13 and X were identified (psi1Rac1-psi4Ra

57 ultiple interval mapping identified areas of chromosomes 4, 13, 15, and 18.

58 tinine, GFR, and CRCL were 2.28 at 176 cM on chromosome 4, 2.19 at 78 cM on chromosome 4, and 1.91 at

59 o the subtelomeric region of the long arm of chromosome 4(4H).

60 d by a terminal deletion of the short arm of chromosome 4 (4p-).

61 ted with the distal part of the short arm of chromosome 4 (4p16.3).

62 associations between ancestry and height on chromosomes 4 (4q21), 15 (15q26) and 17 (17q23).

63 analysis we have localized the HBID gene to chromosome 4 (4q35) with a peak LOD score of 8.97.

64 entric and one pericentric, were revealed in chromosomes 4, 5 and 7.

65 aryotypes involving one or more homologue of chromosomes 4, 5, 6 and 7.

66 density in the identified linkage regions on chromosomes 4, 5, 9, 12, and 14 were also genotyped.

67 f candidate loci under positive selection on chromosomes 4, 5, and 11.

68 Evidence of linkage was also found to chromosomes 4, 5, and 13 (LOD scores >1.5).

69 , 12p, 17q, 19 and 20q, and losses involving chromosomes 4, 5q, 8p, 16q, 17p, 18q and X.

70 five additional tumor-susceptibility loci on chromosomes 4, 6, 7, 9, and 16 (Skts7, Skts12, Skts1, Sk

71 ntified at each time point except those from chromosomes 4, 6, 9, and 13 that were found at all three

72 ngly influencing FEV1 and FVC colocalized on chromosomes 4, 6, and 21.

73 Suggestive linkage to regions of chromosomes 4, 7, 10, and 14 was found.

74 15, and 19 were gained, and entire copies of chromosomes 4, 7, 8, and 14 were lost.

75 11 and 17, as well as three other regions on chromosomes 4, 8, and 10.

76 and chromosome 15 (73%) and partial loss of chromosome 4 (87%), chromosome 7 (80%), chromosome 8 (53

77 ; 145 Mb, NPL = 3.09), as well as regions on chromosomes 4 (91 Mb, NPL = 2.97), 16 (20 Mb, NPL = 2.89

78 with overt toxicity: DUX4 (double homeobox, chromosome 4), a protein with two homeodomains, each sim

79 hybridization revealed loss of distal mouse chromosome 4, a region orthologous with human chromosome

80 loci and one additional suggestive locus on chromosome 4 account for an estimated 40% of the phenoty

81 brid map of the centromeric portion of mouse Chromosome 4 across the Wheels region and refined the po

82 thologous 70-kb non-coding interval on mouse chromosome 4 affects cardiac expression of neighbouring

83 entified a rat with a recombination event on chromosome 4, allowing us to fix 33 Mb of F344 between D

84 entified the introgressed region as 16 Mb of chromosome 4, although a more complete analysis is neces

85 Losses of the complete chromosome 4 and 8p11.21-23.1 were found only in tumorig

86 eles also detected an early flowering QTL on chromosome 4 and a late-flowering QTL on chromosome 6 an

87 ic stiffness: two interacting QTLs (AS-m1 on chromosome 4 and AS-m2 on chromosome16, LOD 8.8) in male

88 ingly, mouse SRG gene was also identified on chromosome 4 and blocking SRG expression with small inte

89 oleracea orthologous segment was located on chromosome 4 and can be distinguished by the presence of

90 an enrichment of zebrafish-specific genes on chromosome 4 and chromosomal regions that influence sex

91 chromosome 6 that interacts with the loci on chromosome 4 and chromosome 9 to affect tumor number.

92 ome showed that the basonuclin2 gene maps to chromosome 4 and consists of six exons spanning approxim

93 ed on the tomato RFLP map on the long arm of chromosome 4 and does not demonstrate linkage to reporte

94 risk loci mapping to the ADH gene cluster on chromosome 4 and extending centromerically beyond it to

95 e tandemly arrayed within the ADH cluster on chromosome 4 and have very high nucleotide similarity to

96 One of these is on the short arm of chromosome 4 and is linked with a cluster of 22-kD alpha

97 IKBKAP is located on the central portion of chromosome 4 and maps to a region in which there is cons

98 ver, FISH revealed a cryptic deletion in one chromosome 4 and reduced alpha satellite in the del(4) a

99 r alcohol dependence and related behavior on chromosome 4 and suggest that ADH2 polymorphisms may acc

100 exploiting the short informative segment of chromosome 4 and the known biology, we propose that Ece1

101 t Dsi1 and Runx3 are closely linked on mouse chromosome 4 and the precedent of the related Runx2 gene

102 y to catalog the transcribed regions of rice chromosome 4 and to reveal organ- and developmental stag

103 s shows (a) the absence of P450 genes on the chromosome 4 and Y, (b) more than half of the P450 genes

104 F344 alleles at the Cia3 and Cia5 regions of chromosomes 4 and 10 reduced CIA severity relative to th

105 prognostic markers TEL-AML1 or trisomies of chromosomes 4 and 10 still provided additional prognosti

106 erior outcomes in patients with trisomies of chromosomes 4 and 10 versus those lacking double trisomi

107 hologues, as well as two human paralogues on chromosomes 4 and 10.

108 eric regions as well as on the short arms of chromosomes 4 and 10.

109 BL1, and MLL translocations and trisomies of chromosomes 4 and 10.

110 deletion 17p, del(17p), and translocation of chromosomes 4 and 14, t(4;14), conferring a poor outcome

111 ghly polymorphic microsatellite markers from chromosomes 4 and 16, at an average density of 1 marker

112 as narrowed female OA susceptibility loci on chromosomes 4 and 16.

113 o chromosomes 5 and 17, anti-chromatin Ab to chromosomes 4 and 17, glomerulonephritis to chromosomes

114 The genome scan identified regions on chromosomes 4 and 18 with logarithm of the odds favoring

115 affecting tumor latency between the loci on chromosomes 4 and 18.

116 ion between acrocentric chromosomes, whereas chromosomes 4 and 19 in Gorilla gorilla are the products

117 We note that mouse chromosomes 4 and 2 do not contain Tbx5 or Tbx1, genes p

118 o explore the hypothesis that the signals on chromosomes 4 and 20 are differentially attributable to

119 t interactions were detected between loci on chromosomes 4 and 5, and 16 and 15.

120 QTL on chromosomes 4 and 6 were new and designated as Lxw1 and

121 as shown to share syntenous blocks with rice chromosomes 4 and 7.

122 le copies, which are linked and localized to chromosomes 4 and W.

123 lcohol dehydrogenase genes (ADH2 and ADH3 on chromosome 4) and one aldehyde dehydrogenase gene (ALDH2

124 MORF4 (mortality factor on chromosome 4) and the novel related MRG (MORF4-related g

125 at 176 cM on chromosome 4, 2.19 at 78 cM on chromosome 4, and 1.91 at 103 cM on chromosome 3, respec

126 was identified and localized to distal mouse chromosome 4, and accounts for some of the genetic varia

127 ility to bladder infection was identified on chromosome 4, and C3H/HeJ alleles at this locus interact

128 ATJ11 is encoded by a single-copy gene on chromosome 4, and is expressed in all plant organs exami

129 Two loci, on distal chromosome 4 (Ap3q) and proximal chromosome 7 (Ap7q), st

130 cipated, the pericentric heterochromatin and chromosome 4 are on average enriched for the "silencing"

131 The FEV1/FVC ratio was linked to chromosome 4 around 28 centimorgans (cM; D4S1511) with a

132 icant quantitative trait loci (QTL) on mouse chromosome 4 (around 58.2 cM) and chromosome 11 (between

133 3.09), chromosome 3 at 26.3 cM (LOD = 1.27), chromosome 4 at 135.3 cM (LOD = 2.63), chromosome 5 at 1

134 ons of linkage for reflected wave amplitude: chromosome 4 at 181 cM (logarithm of odds [LOD]=4.93, pe

135 to an individual principal component was on chromosome 4 at 208 cM (P = 0.00007).

136 A single QTL for body weight on chromosome 4 at 48 weeks of age had the largest additive

137 affected-only LOD score of 2.8) centered on chromosome 4 at 4q35.1-q35.2, a critical region that doe

138 e consisted of only a single exon located on chromosome 4 at 56.5-56.8 cM flanked by marker genes kcn

139 aneous lung adenocarcinomas displayed LOH on chromosome 4 at a frequency of 77%, whereas a frequency

140 gnificant evidence for linkage was noted for chromosome 4 at D4S1564 with a MLS of 3.65 (P = 0.044).

141 d copy of the gene family is also located on chromosome 4S at a site approximately 20 cM closer to th

142 ive linkage to bloodstream infection, all on chromosome 4, at 46.6 centimorgan (logarithm of odds, 2.

143 ividual backcross mice confirmed linkages to chromosomes 4 (Athsq1, logarithm of odds = 6.2) and 6 (A

144 that iddm4 is centered on a small segment of chromosome 4 bounded by the proximal marker D4Rat135 and

145 ence of a 554 bp palindromic sequence at the chromosome 4 breakpoint and a 22q11.2 location within th

146 were designed from the sequence of a 200 kb, chromosome 4, breakpoint-spanning BAC to generate PRINS

147 breakpoints fell in BCR introns whereas the chromosome 4 breakpoints were within PDGFRA exon 12.

148 risis, specifically in SCC lines with LOH on chromosome 4, but chromosomes 3, 6, 11 and 15 were witho

149 The BLIN-4 sublines maintained the ring chromosome 4, but the trisomy 8 and trisomy 18 segregate

150 of the sks locus on a 0.3-Mb region of mouse chromosome 4 by linkage analysis.

151 om a hemizygous deletion of the short arm of chromosome 4, called the WHS critical region (WHSC).

152 minant of cytokine production to a region of chromosome 4 carrying the Toll-like receptor 4 (TLR4) ge

153 Human chromosome 4 caused a delayed crisis, specifically in SC

154 eats harbored in the core region of the rice chromosome 4 centromere (CEN4).

155 large inversion spanning nearly all of mouse chromosome 4 (Chr 4).

156 imer, we identified a 5.5-kb DNA sequence on chromosome 4 (Chr.

157 is genetically 98.4% B6 and carries the C3H chromosome 4 (Chr. 4) QTL genomic DNA.

158 trait locus (QTL) was tentatively mapped to chromosome 4 (chr.4).

159 rthologous 70-kb noncoding interval on mouse chromosome 4 (chr4(Delta70kb/Delta70kb) mice) is associa

160 s to map 1358 S/MARs on Arabidopsis thaliana chromosome 4 (chr4).

161 In pedigrees of chromosome 4 cluster KRAB-ZFP mutants, we identified num

162 One mutation was mapped to an interval on chromosome 4 containing At4g34740, which encodes an isof

163 inant inbred strains identified a segment on chromosome 4 containing the gene encoding Munc13-2, whic

164 line (SHRchr4) that incorporates a piece of chromosome 4 containing wild-type CD36.

165 The known segregating segment of chromosome 4 contains only 18 genes, among which Ece1, e

166 browser, defines that PNRC2 gene, located on chromosome 4, contains 3 exons: 166 bp-exon I, 205 bp-ex

167 we report suggestive evidence for linkage on chromosome 4 (D4S403, P=.00012).

168 g and Hi-C, we assembled the sex-determining chromosome 4 de novo.

169 Distal chromosome 4 deletions occur in a significantly higher p

170 g recurrent chromosome 11 amplifications and chromosome 4 deletions, syntenic with human 17q21-25 and

171 d tumor-derived cell lines exhibited loss of chromosome 4, deletions in chromosomes 3p12.3-13, 8p11.1

172 Susceptibility loci on chromosome 4, designated Prsq4 and Prsq5, were identifie

173 Deletions of the long arm of chromosome 4 detectable by cytogenetic analysis (standar

174 z) lupus-susceptibility congenic interval on chromosome 4 display high titers of polyclonal autoantib

175 sence of AEA-specific promoting genes on NZB chromosome 4, documented a marked influence of backgroun

176 zygosity were 32% higher in Texel animals on chromosome 4 due to a region of increased heterozygosity

177 hich correlated with recurring loss of mouse chromosome 4D-E, a region that is orthologous to distal

178 TD1 on chromosome 1, in addition to genes on chromosomes 4 (eg, GABRA2) and 6 (eg, CNR1), may be asso

179 een the ancestral X and previously autosomal chromosome 4 (element B).

180 DKN2A), and the corresponding locus on mouse chromosome 4, encodes three distinct products: two membe

181 gains of chromosome 1q and a small region of chromosome 4 encompassing KDR and KIT were identified by

182 essed fragment of New Zealand White (NZW) on chromosome 4 encompassing Lbw2, a locus previously linke

183 rolling for motif and initial repeat number, chromosome 4 exhibited an elevated mutation rate relativ

184 he banded portion of Drosophila melanogaster chromosome 4 exhibits euchromatic and heterochromatic ch

185 Chromosome 4 explained a relatively large proportion of

186 mbers are found in a roughly tandem array on chromosome 4S forming a dense gene cluster 168,489-bp lo

187 rved unannotated regions on the short arm of chromosome 4 from Arabidopsis were experimentally verifi

188 congenic strain that possesses a segment of chromosome 4 from the C57BL/6J (donor) mouse strain supe

189 In contrast, the chromosome 4 gene cluster factor (0.14 variance) encodin

190 herited as a complex trait that includes the chromosome 4 gene Tda1; (3) B6 Dax1-/Y fetal gonads init

191 In particular, two SNPs (chromosome 4D) had the maximum R(2) values: SNP 1114200

192 pping analyses suggest that a gene(s) on mid-chromosome 4 has pleiotropic effects on multiple CNS hyp

193 Chromosome 4 has received attention primarily related to

194 and 63 compared to the centromere from human chromosome 4 (heterochromatic) and the human glyceraldeh

195 to several chromosomal locations, including chromosome 4; however, none of these have been analyzed

196 An in silico analysis of SNPs on chromosome 4D identified two candidate gene hits, TraesC

197 ation revealed frequent loss of distal mouse chromosome 4 in a region syntenic to human chromosome 1p

198 locus, GL4, controlling the grain length on chromosome 4 in African rice, which regulates longitudin

199 An LOD of 2.2 was noted on chromosome 4 in the region of the gamma-aminobutyric aci

200 human enamelin is located on the long arm of chromosome 4, in a region previously linked to an autoso

201 ridization revealed that mNASP is present on chromosome 4, in an area that corresponds to band 4D1, a

202 Interesting candidates on chromosome 4 included the Padi family, encoding the pept

203 ying other quantitative trait loci mapped to chromosome 4, including loci affecting voluntary alcohol

204 tion, we show that millions of base pairs of chromosome 4, including the telomere, TEL4N, and much of

205 MORF4 (mortality factor on chromosome 4) induces senescence in a subset of human tu

206 We identified a pericentric inversion of chromosome 4, inv(4)(p13q21) that segregates with cleft

207 containing genes, located on the long arm of chromosome 4, is expressed in a sharp peak during zygoti

208 Iddm1, on chromosome 4, is responsible for a lymphopenia (lyp) phe

209 (glutamate receptor ionotropic kainate 3)), chromosome 4 (KLHL2 (Kelch-like protein 2)), chromosome

210 erved during early embryo sac development of chromosome 4S(L) addition lines to wheat, often leading

211 The cuckoo chromosome 4S(L) from Aegilops sharonensis is preferenti

212 In the presence of chromosome 4S(L), treatment with the hypomethylating age

213 series of independent mutations on proximal chromosome 4 leading to dominant head-bobbing and circli

214 , and a recent study demonstrated a locus on chromosome 4 linked to exceptional longevity, indicating

215 ttes per day (CPD)) shared chromosome 19 and chromosome 4 loci with the NMR, and that cotinine and a

216 t39 with a maximum LOD score of 9.0 and to a chromosome 4 locus near D4Mit170.

217 tive of linkage were identified at 176 cM of chromosome 4 (lod = 2.7), 143 cM of chromosome 5 (lod =

218 aks remained similar (lod = 2.2 at 176 cM on chromosome 4; lod = 1.7 at 146 cM on chromosome 5; lod =

219 t linkage to a single locus (8 megabases) on chromosome 4 (logarithm of the odds [LOD] score = 6.9, P

220 confirmation with an independently produced chromosome 4 loss of heterozygosity variant positioned t

221 so identified a putatively causal variant on chromosome 4 mapping to TMPRSS11E and demonstrated an as

222 roximately 18 Mb disease-associated locus on chromosome 4 (maximal logarithm of odds score 4.4 at D4S

223 ation across roughly 20% of the Ostrinia sex chromosome (~4 Mb).

224 A MI oxygenase (MIOX) gene was identified in chromosome 4 (miox4) of Arabidopsis ecotype Columbia, an

225 This family comprises MORF on chromosome 4 (MORF4) and MORF-related genes on chromosom

226 based on the ability of Mortality factor on chromosome 4 (MORF4) to induce replicative senescence in

227 family, lying within a tight cluster on rat chromosome 4, mouse chromosome 6, and human chromosome 7

228 ied statistically significant linkage within chromosome 4 near microsatellite D4S1564.

229 inkage to chromosome 1, near marker D1S3462; chromosome 4, near marker D4S2361; chromosome 5, near ma

230 angle glaucoma locus, GLC1Q, in a region on chromosome 4 not previously associated with glaucoma.

231 orresponding to the ABI1-Rps2-Ck1 segment on chromosome 4 of Arabidopsis thaliana was sequenced in Br

232 vestigate a paracentric 1.17-Mb inversion on chromosome 4 of Arabidopsis thaliana with nucleotide pre

233 itotic origin and linked genetic variants on chromosome 4 of maternal genomes.

234 In addition, a gene on chromosome 4 of the Arabidopsis genome (At4g33360), call

235 lyses revealed a single plasmid insertion in chromosome 4 of the tla3 nuclear genome, causing deletio

236 ntity, is encoded in a 4.5 Mb duplication of chromosome 4 on chromosome 2.

237 es, with multiple strains being trisomic for Chromosome 4 or Chromosome 7.

238 ked to either contraction of D4Z4 repeats on chromosome 4 or to mutations in the SMCHD1 gene, both of

239 or the effect of TGF-beta2 was identified on chromosome 4 overlapping with a QTL regulating the frequ

240 some 18 (P = 1.0 x 10(-5)), and rs2710833 on chromosome 4 (P = 6.3 x 10(-7)).

241 , which promotes the resolution of dicentric chromosomes(4), plays a prominent role in chromothriptic

242 The QTL on chromosome 4 (qHTSF4.1) is the same QTL previously ident

243 The chromosome 4 QTL affects multiple femoral anatomic featu

244 The colocalizing chromosome 4 QTL Bmd7 (for bone mineral density 7) incre

245 e to Phytophthora crown rot were detected on chromosome 4 (QtlPC-C04), 11 (QtlPC-C11) and 14 (QtlPC-C

246 locus in mouse, mapped to the distal end of chromosome 4 (refs.

247 he MRG15 (MRG stands for mortality factor on chromosome 4 related gene) and Pf1 subunits.

248 chromosome 2, and 186 million base pairs for chromosome 4, representing more than 99.6% of their euch

249 overed 2 genome-wide significant variants on chromosome 4 (rs13113697; closest gene, HS3ST1; odds rat

250 or protein-binding family B member 2 (APBB2; chromosome 4, rs59892895T>C) with primary open-angle gla

251 tion was observed in an intergenic region on chromosome 4 (rs753129; 'AD+PvAD-P' P=2.85 x 10(-7); 'AD

252 al segment of DNA that extends for >31 kb on chromosome 4 seems to have introgressed into modern Afri

253 NOD mice with B10 resistance alleles only on chromosome 4 show autoantibody formation without liver i

254 Two regions of chromosome 4 showed significant linkage to CD4:CD8 ratio

255 tion of chromosomal length and gene density, chromosome 4 significantly deviates from this pattern an

256 derived lupus susceptibility locus on murine chromosome 4, Sle2(z), has previously been noted to enge

257 were sequenced and the organization of this chromosome 4-specific repeat was examined.

258 uclear periphery, perhaps accounting for the chromosome 4 specificity of the disease.

259 t diabetes susceptibility genes (Idd)9/11 on chromosome 4, suggesting common genetic origins for T ce

260 localized QTL, including a multitrait QTL on chromosome 4 that affects six enzyme activities, three m

261 The GWAS identified three SNPs on chromosome 4 that are significantly associated with both

262 GWAS to identify SNPs in a genomic region on chromosome 4 that associate with serum urate levels and

263 ee strains had amplifications in a region of chromosome 4 that includes the high-affinity hexose tran

264 t gene on human chromosome 9p21-22 and mouse chromosome 4 that is expressed in adult skeletal muscle.

265 ed D4Z4 is found in a tandem repeat array on chromosome 4 that is partially deleted in facioscapulohu

266 ead, they revealed a single region of LOH on chromosome 4 that occurred via somatic recombination/gen

267 Cia3 is a locus on rat chromosome 4 that regulates severity and joint damage in

268 ffects tumor multiplicity, and a modifier on chromosome 4 that significantly affects tumor latency an

269 by contractions of the D4Z4 repeat array on chromosome 4 to 1-10 units (FSHD1), or by mutations in t

270 ly 8.7-Mb BAC contig of Arabidopsis thaliana Chromosome 4 to trace homeologous chromosome regions in

271 The long arm of Chromosome 4 underwent a dramatic developmentally regula

272 /FVC was associated with a genomic region on chromosome 4 [upstream of HHIP] (lowest p-value = 5.94 x

273 ysis of the transcriptional activity of rice chromosome 4 using a tiling path microarray based on PCR

274 nificant linkage to D4Mit203 at 128.50 Mb on chromosome 4 was detected with animals that were >12 wee

275 The NOR Idd9/11 resistance region on chromosome 4 was found to diminish the diabetogenic acti

276 A locus Adnz1 on chromosome 4 was linked to antinuclear antibody (ANA) an

277 A. thaliana line in which a portion of Col-0 chromosome 4 was replaced by sequences of another ecotyp

278 Sle2 on chromosome 4 was significantly linked to glomerulonephri

279 ADH1B, on chromosome 4, was the lead locus for both populations: f

280 a functional cancer mortality gene on human chromosome 4 we introduced a complete or fragmented copy

281 fied by the CXC chemokine genes clustered on chromosome 4, we demonstrate that NF-kappaB might be a p

282 Sle2 murine lupus susceptibility interval on chromosome 4, we undertook this study to investigate whe

283 o KRAB-ZFP gene clusters on chromosome 2 and chromosome 4 were nonetheless viable.

284 me 15), and Rnf220 (Ring finger protein 220; chromosome 4) were considered candidate genes.

285 Two genomic sites, DD20 and DD43 on chromosome 4, were mutagenized with frequencies of 59% a

286 ch are normally silenced, at the position on chromosome 4 where active rRNA genes are normally locate

287 The murine gene is located on chromosome 4, where other type I murine IFN genes, IFN-a

288 an interstitial deletion in the long arm of chromosome 4, where the p16(INK4a) gene resides, and SM1

289 mapping located RPP2 to a 200-kb interval on chromosome 4, which contained four adjacent TIR:NB:LRR g

290 for momilactone production, located on rice chromosome 4, which contains two cytochrome P450 (CYP) m

291 remodelling, and show that a short region on chromosome 4, which encodes two essential invasion genes

292 Crossovers even occur on the small chromosome 4, which normally never has meiotic crossover

293 ion, with the exception of a small region of chromosome 4, which was significantly overrepresented wi

294 lts suggest the existence of a gene on human chromosome 4 whose dysfunction contributes to the contin

295 confirm a quantitative trait locus (QTL) on chromosome 4 with a large effect on predisposition to al

296 We also identified a region on chromosome 4 with a LOD score of 3.73 (P=0.0012) near ma

297 original BM leukemic blasts harbored a ring chromosome 4 with a low percentage of cells also having

298 trains and identified significant linkage on chromosome 4 with candidate genes that associate with V2

299 ill evidence for association of this part of chromosome 4 with ESRD.

300 ne, by using recombination-based methods, to chromosome 4, within a quantitative trait locus for alco