ライフサイエンスコーパス: ciliogenesis

1 find that centrioles degenerate early during ciliogenesis.

2 romises normal neural tube closure (NTC) and ciliogenesis.

3 lagellar transport A complex assembly during ciliogenesis.

4 body of the cilium and is upregulated during ciliogenesis.

5 ssion in the (ret)Arl13b(-/-) retina rescued ciliogenesis.

6 his process, at least in part, by modulating ciliogenesis.

7 riole distal appendage protein important for ciliogenesis.

8 itin ligase cofactor, which was required for ciliogenesis.

9 nduce its separation from the mother abolish ciliogenesis.

10 ands induces Cyp1a1 but not Ccno and impeded ciliogenesis.

11 rbates TZ anomalies and completely abrogates ciliogenesis.

12 SR2) some of which have established links to ciliogenesis.

13 cp110 to produce optimal Cp110 levels during ciliogenesis.

14 tes with and cooperates with Pk3 to regulate ciliogenesis.

15 cting as both a suppressor and a promoter of ciliogenesis.

16 onemes and basal bodies, and is required for ciliogenesis.

17 served role for Girdin in BB positioning and ciliogenesis.

18 ilia, a regulatory process indispensable for ciliogenesis.

19 sical removal of the remnant greatly impairs ciliogenesis.

20 at high levels, while optimal levels promote ciliogenesis.

21 together with the NPHP module to facilitate ciliogenesis.

22 heal epithelia, and its loss inhibits motile ciliogenesis.

23 t antagonistically with ARL-3, in regulating ciliogenesis.

24 act as a suppressor to control the timing of ciliogenesis.

25 Knockdown of FAM92A in RPE1 cells impairs ciliogenesis.

26 ow that excess inactivated ARL-3 compromises ciliogenesis.

27 centrosome and coordinate the initiation of ciliogenesis.

28 form a tubulin-binding module important for ciliogenesis.

29 ciliary vesicle formation, an early event in ciliogenesis.

30 a subunit of the IFT-B complex required for ciliogenesis.

31 volutionary derivations of compartmentalized ciliogenesis.

32 small calcium-binding protein, centrin2, in ciliogenesis.

33 amically localized TZ proteins for cytosolic ciliogenesis.

34 ormed, cultured B and T cells caused primary ciliogenesis.

35 ll morphology, proliferation, migration, and ciliogenesis.

36 the cell cycle and without progression into ciliogenesis.

37 impact of proms on two distinct examples of ciliogenesis.

38 wed that its levels inversely correlate with ciliogenesis.

39 l (RPE1) cells resulted in severe defects in ciliogenesis.

40 d mechanism fundamental to the regulation of ciliogenesis.

41 iole to the tip of the primary cilium during ciliogenesis.

42 es IFT protein mislocalization and disrupted ciliogenesis.

43 ological events, including cell division and ciliogenesis.

44 sms through which miR-34/449 regulate motile ciliogenesis.

45 protein 88, proteins that are essential for ciliogenesis.

46 basal body, two critical steps in initiating ciliogenesis.

47 e required for normal lung morphogenesis and ciliogenesis.

48 ting that centrosomal CK1delta has a role in ciliogenesis.

49 er centriole to the cellular membrane during ciliogenesis.

50 lagellar transport protein 20 homologue, and ciliogenesis.

51 is required for both lung tubulogenesis and ciliogenesis.

52 Centrioles are essential for ciliogenesis.

53 during activation of Rab GTPases involved in ciliogenesis.

54 e interaction is essential for promoting GNP ciliogenesis.

55 ) proteins for centrosome recruitment during ciliogenesis.

56 nd a WDR44-pAkt-phosphomimetic mutant blocks ciliogenesis.

57 ealing an unexpected regulatory dimension in ciliogenesis.

58 ecreted molecules are known to contribute to ciliogenesis.

59 at deliver membrane proteins to cilia during ciliogenesis.

60 egarding the proteins involved in regulating ciliogenesis.

61 uctural and regulatory factors with roles in ciliogenesis.

62 s process and most genes required for motile ciliogenesis.

63 (LPA) inhibits Rab11a-Rabin8 interaction and ciliogenesis.

64 ll GTPase Rab11-Rab8 cascade is required for ciliogenesis.

65 isease models, Tulp3 mutations do not affect ciliogenesis.

66 ssibly involved in centriolar elongation and ciliogenesis.

67 ntiation, such as polarity establishment and ciliogenesis.

68 e 11, and its kinase activity is crucial for ciliogenesis.

69 iary vesicles to the mother centriole during ciliogenesis.

70 ed with basal bodies during and after motile ciliogenesis.

71 TTBK2 substrates associated with its role in ciliogenesis.

72 ewly identified partner of Dvl in regulating ciliogenesis.

73 nate the end of mitosis and the beginning of ciliogenesis?

74 at the synapse and basal body docking during ciliogenesis [1, 4-8], suggesting that CTL centrosomes m

75 Cep83, required for membrane contact during ciliogenesis [11], impairs CTL secretion.

76 Mutations in genes that disrupt ciliogenesis also cause kidney cysts as part of a "cilio

77 LRRK2-mediated centrosomal cohesion and ciliogenesis alterations are observed in patient-derived

78 lity that either centrosomal cohesion and/or ciliogenesis alterations may serve as cellular biomarker

79 gnaling pathways, cell cycle regulation, and ciliogenesis, among others.

80 mitochondrial function as a determinant for ciliogenesis and a cause for heterotaxy.

81 deficiency resulted in a disruption of renal ciliogenesis and a polycystic kidney disease phenotype i

82 g and membrane supply during early stages of ciliogenesis and adherens junction remodeling.

83 function revealed a reciprocal influence on ciliogenesis and affected cilia-dependent processes in z

84 of LUZP1 reduces F-actin levels, facilitates ciliogenesis and alters Sonic Hedgehog signaling, pointi

85 membrane adhesion glycoprotein in promoting ciliogenesis and barrier function as part of a network o

86 on of KIF14 specifically leads to defects in ciliogenesis and basal body (BB) biogenesis, as its abse

87 ing the functional interconnectivity between ciliogenesis and cell cycle progression.

88 ed light on sensitive mechanisms controlling ciliogenesis and cell signalling that are essential to e

89 sicular trafficking, a pathway important for ciliogenesis and cell signalling.

90 erapeutic approaches aimed at restoration of ciliogenesis and cellular differentiation as a promising

91 iliary components for assembly very early in ciliogenesis and chloride transport by ANO1/TMEM16A is r

92 demonstrating that transcriptome related to ciliogenesis and cilia function is significantly impaire

93 netic transcriptional program responsible of ciliogenesis and cilia function is significantly impaire

94 tes the expression of many genes involved in ciliogenesis and cilia function.

95 several organ systems and tissues regarding ciliogenesis and cilia maintenance using congenital and

96 ) subfamily have been shown to be crucial to ciliogenesis and cilia maintenance.

97 Both LUZP1 and EPLIN interact with known ciliogenesis and cilia-length regulators and as such rep

98 and show that elongation of cilia, impaired ciliogenesis and ciliary composition defects are typical

99 CAs, its kinase activity is dispensable for ciliogenesis and ciliary function revealing that FAK pla

100 we examined the role of this protein in both ciliogenesis and ciliary function.

101 nd that both domains are required for proper ciliogenesis and ciliary function.

102 This interaction is indispensable for both ciliogenesis and ciliary function.

103 Several key regulators of ciliogenesis and ciliary signaling are mutated in humans

104 tract infections due to profound defects in ciliogenesis and complete loss of mucociliary clearance.

105 Together, our findings establish primary ciliogenesis and consequent Hh signaling as a key mechan

106 f ceramide generated by nSMase2 in stem cell ciliogenesis and differentiation.

107 of the Xenopus laevis epidermis compromised ciliogenesis and directional fluid flow.

108 or F-BAR proteins and membrane tubulation in ciliogenesis and explains how the intracellular cilium e

109 molecular trafficking machineries underlying ciliogenesis and Hh signaling can be segregated, thereby

110 pmental disorders, in which improper primary ciliogenesis and Hh signaling play a major role.

111 hes NRF2-mediated inhibition of both primary ciliogenesis and Hh signaling.

112 molecular mechanism of kinase regulation in ciliogenesis and identify CEP83 as a key substrate of TT

113 ese data suggest a novel role for SDCCAG3 in ciliogenesis and in localization of cargo to primary cil

114 t protein 88 (IFT88), a crucial component of ciliogenesis and intraciliary transport.

115 ve morphogenesis and implicate disruption of ciliogenesis and its downstream pathways as contributory

116 marily responsible for distinct functions in ciliogenesis and microtubule anchoring, respectively, th

117 Our data provide new insights into ciliogenesis and might be of particular interest for inv

118 Tuba most likely plays a critical role in ciliogenesis and nephrogenesis by regulating Cdc42 activ

119 cific guanine nucleotide exchange factor, in ciliogenesis and nephrogenesis using Tuba knockdown Madi

120 a new genetic module, which we term CPLANE (ciliogenesis and planar polarity effector), and an exten

121 d IFT88 in adult mice to study photoreceptor ciliogenesis and protein trafficking.

122 ia serves as a diffusion barrier to regulate ciliogenesis and receptor localization for key signaling

123 natal Tmem67 mutant cerebellum had disrupted ciliogenesis and reduced responsiveness to Shh signallin

124 rotein trafficking complex, is essential for ciliogenesis and regulated by multiple Rho and Rab famil

125 Myc suppresses ciliogenesis and reprograms the transcriptome of SHH-dep

126 se data show that Nek2 is a switch balancing ciliogenesis and resorption in the development of LR asy

127 t the exocyst is necessary for photoreceptor ciliogenesis and retinal development, most likely by tra

128 an amino-terminal domain of PCM1 can restore ciliogenesis and satellite localization of certain prote

129 These results implicate LRRK2 in primary ciliogenesis and suggest that Rab-mediated protein trans

130 summary, this work shows that Tgifs regulate ciliogenesis and suggests that Evi5l mediates at least p

131 gulates preciliary trafficking of Rabin8 and ciliogenesis and support previous findings that the TRAP

132 stnatal cardiomyocytes are unable to undergo ciliogenesis and the nuclear envelope adopts the functio

133 resembled that of mutant mice with impaired ciliogenesis and/or ciliary motility of the node.

134 fluence mitochondrial biogenesis also affect ciliogenesis, and can cause heterotaxy-like phenotypes i

135 of protein modules in centriole duplication, ciliogenesis, and centriolar satellite biogenesis and hi

136 r-78 is dispensable for CEP131 localization, ciliogenesis, and centriole duplication, it is essential

137 cell polarity and differentiation, abnormal ciliogenesis, and changes in mitosis and cell cycle prog

138 regulating genes that control cell movement, ciliogenesis, and cilia function.

139 PDGFRalpha is up-regulated during ciliogenesis, and ciliary localization of the receptor i

140 e connecting cell cycle machinery, effective ciliogenesis, and HH signaling.

141 kinase 2 (TTBK2) is a critical regulator of ciliogenesis, and is also mutated in a hereditary neurod

142 dynamic cellular processes, such as mitosis, ciliogenesis, and neuronal morphogenesis.

143 ts critical for outer segment morphogenesis, ciliogenesis, and synaptic transmission.

144 We show that 3M genes are involved in ciliogenesis, and that patient fibroblasts lack cilia.

145 transitions of the midbody, the beginning of ciliogenesis, and the accumulation of ciliated cells.

146 ate collagen biogenesis, muscle development, ciliogenesis, and various aspects of cell proliferation

147 Wnt signaling and ciliogenesis are core features of embryonic development

148 at regulate BB positioning in the context of ciliogenesis are largely unknown.

149 red cells, yet serum factors associated with ciliogenesis are unknown.

150 Unexpectedly, kif3a function precedes ciliogenesis as ciliary basal bodies are mispositioned i

151 asal bodies to the actin cytoskeleton during ciliogenesis as well as in mature multiciliated cells.

152 s suggest that IL-6/Stat3 signaling promotes ciliogenesis at multiple levels, including increases in

153 PACSINs function early in ciliogenesis at the ciliary vesicle (CV) stage to promot

154 ived from affected individuals showed normal ciliogenesis but severely altered Hh-signal transduction

155 Many proteins are known to promote ciliogenesis, but mechanisms that promote primary cilia

156 Cellular quiescence potentiates ciliogenesis, but the regulation of basal body formation

157 Loss of PCM1 blocks ciliogenesis by abrogating recruitment of ciliary vesicl

158 sults point to an undiscovered regulation of ciliogenesis by Lys63 ubiquitination and provide new per

159 at the centrosome/ciliary base, is vital for ciliogenesis by regulating the CEP164-dependent recruitm

160 Thus, PCM1 promotes ciliogenesis by tethering a key E3 ligase to satellites

161 During early stages of ciliogenesis, Cby1 is required for the efficient recruit

162 ubiquitin proteasome system (UPS), controls ciliogenesis, cilia elongation and Hh signal transductio

163 perspectives for the understanding of normal ciliogenesis, ciliopathies and cancer.

164 Because of its dual role in ciliogenesis, Cp110 levels must be precisely controlled.

165 h the primary cilium, is necessary for renal ciliogenesis, cystogenesis, and tubulogenesis.

166 iding a possible molecular mechanism for the ciliogenesis defect in Cby1(-/-) cells.

167 Golgi trafficking contribute to the observed ciliogenesis defects and provide an unanticipated, highl

168 the LRRK2-mediated centrosomal cohesion and ciliogenesis defects are distinct cellular readouts of t

169 Conversely, the pathogenic LRRK2-mediated ciliogenesis defects correlate with the centrosomal accu

170 Fltp knock-out mice show BB docking and ciliogenesis defects in multiciliated lung cells.

171 ited in Xenopus embryos, MCCs show transient ciliogenesis defects similar to those seen in mutants of

172 ts from affected individuals did not display ciliogenesis defects, indicating that MAPKBP1 may repres

173 otein not yet ciliopathy-associated, display ciliogenesis defects.

174 a JBTS patient with a JBTS17 mutation showed ciliogenesis defects.

175 rom Csnk1d (CK1delta)-null mice also exhibit ciliogenesis defects.

176 -of-function mutations in genes required for ciliogenesis, demonstrating that the fungus induced para

177 Such compartmentalized ciliogenesis depends on the core intraflagellar transpor

178 Ciliogenesis depends on the sphingolipid ceramide and it

179 Ciliogenesis deregulation caused by LUZP1 or EPLIN loss

180 mantling of the exocyst resulted in impaired ciliogenesis, disrupted ciliogenic signaling and a spect

181 ed degradation of HYLS-1 after initiation of ciliogenesis does not affect ciliary structures.

182 FAK down-regulation leads to aberrant ciliogenesis due to impaired association between the bas

183 a support the exocyst as required for normal ciliogenesis during aortic valve morphogenesis and impli

184 ate-dependent methylation of septins governs ciliogenesis during neural tube closure.

185 ful subcellular analyses as well as in vitro ciliogenesis experiments in CCNO-mutant cells showed def

186 Vertebrate cells can initiate ciliogenesis from centrioles at the cell center, near th

187 and reduces the expression of both notch and ciliogenesis genes (Mcidas, Rfx2, and Myb) with distinct

188 development, sensory placode specification, ciliogenesis, germ layer specification).

189 A Wnt inhibitor likewise restores ciliogenesis in 3D IMCD3 cultures, emphasizing the impor

190 e-localized RILPL1, which may interfere with ciliogenesis in a disease-relevant context.

191 Siah2 supports ciliogenesis in a feed-forward fashion by restraining ci

192 s to demonstrate that BBs remodel to support ciliogenesis in a subset of sensory neurons.

193 Here, we show abrogated protein levels and ciliogenesis in affected fibroblasts.

194 e conclusion that kif3a is indispensable for ciliogenesis in all cells, including photoreceptors.

195 RFX TFs play key functions in the control of ciliogenesis in animals.

196 Whereas only one RFX factor regulates ciliogenesis in C. elegans, several distinct RFX factors

197 centrioles and regulates BB positioning and ciliogenesis in Caenorhabditis elegans sensory neurons a

198 tment with beta-catenin inhibitors to rescue ciliogenesis in ccRCC.

199 in mice, we found kidney cysts and decreased ciliogenesis in cells surrounding the cysts.

200 e-targeted Neurl-4 was sufficient to restore ciliogenesis in cells with manipulated daughter centriol

201 a downstream target of AurA, HDAC6, restores ciliogenesis in ceramide-depleted cells.

202 Efficient ciliogenesis in chicken DT40 B lymphocytes required cent

203 toceramide and ceramide that is critical for ciliogenesis in Chlamydomonas and murine ependymal cells

204 has been associated with cilia function and ciliogenesis in directing the orientation of cilia and b

205 e distal end of the cilia during cytoplasmic ciliogenesis in Drosophila sperm.

206 um starvation led to a two-fold reduction in ciliogenesis in fibroblasts derived from pathogenic LRRK

207 riole are essential for the initial steps of ciliogenesis in G1/G0 phase of the cell cycle.

208 these severe diseases and the mechanisms of ciliogenesis in general.

209 TTBK2 is probably involved in the control of ciliogenesis in human cells.

210 ein kinase 1 delta (CK1delta) blocks primary ciliogenesis in human telomerase reverse transcriptase i

211 exocyst trafficking complex is required for ciliogenesis in kidney tubule cells.

212 members KIF3A/KIF3C and KIF17 cannot rescue ciliogenesis in Kif3a/Kif3b double-knockout cells or del

213 ng abnormalities while rapamycin facilitated ciliogenesis in LS patient cells.

214 ric KIF3A/KIF3B/KAP kinesin-2 motor prevents ciliogenesis in mammalian cells and has hindered an unde

215 To investigate whether Arl13b has a role in ciliogenesis in mammalian kidney and whether loss of fun

216 ERK7 has been recently implicated in ciliogenesis in metazoan cells, and our data suggest tha

217 redundant function in the control of motile ciliogenesis in mice.

218 lizes to mature centrioles, is important for ciliogenesis in multiciliated airway epithelia in mice,

219 on kinase (FAK) as an important regulator of ciliogenesis in multiciliated cells.

220 highly enriched in cilia and is required for ciliogenesis in multiple organs.

221 RNAi screen to identify novel inhibitors of ciliogenesis in normal and basal breast cancer cells.

222 gated the uncharacterized process of primary ciliogenesis in polarized epithelial cells.

223 Here we show that inhibition of ciliogenesis in POMC-expressing developing hypothalamic

224 ata suggests that MCM2 and 7 exert a role in ciliogenesis in post-mitotic tissues.

225 CRISPR-Cas9 inactivation of ADAMTS9 impaired ciliogenesis in RPE-1 cells, which was restored by catal

226 onsistent with growth impairment and altered ciliogenesis in the absence of CDK10.

227 s have been reported to degenerate following ciliogenesis in the C. elegans embryo, although neither

228 natal leptin surge have a profound impact on ciliogenesis in the hypothalamus of neonatal mice; throu

229 iculum, vesicular basolateral targeting, and ciliogenesis in the kidney.

230 Loss of CCDC11 leads to defective ciliogenesis in the pronephros and within the Kupffer's

231 cilium as it utilizes the same machinery as ciliogenesis including the nucleation of microtubules at

232 e nimbus") enriched in proteins required for ciliogenesis, including the small GTPases Cdc42 and Arl1

233 ntrosome and catalytically active to promote ciliogenesis independently of NF-kappaB.

234 gellar transport-88, a protein essential for ciliogenesis, inhibits premature senescence induced by t

235 n promotes Rabin8 preciliary trafficking and ciliogenesis-initiating events at the mother centriole.

236 LPA/LPAR1 regulates ciliogenesis initiation via downstream PI3K/Akt activati

237 regulates Rabin8 preciliary trafficking and ciliogenesis initiation.

238 ignaling scaffold that is critical to proper ciliogenesis, interacts with Drg1 (developmentally regul

239 Our findings suggest that ciliogenesis is coupled to the abundance and function of

240 The function of TTBK2 in ciliogenesis is critically dependent on its kinase activ

241 ientation of cilia (rotational polarity) and ciliogenesis is established.

242 on Transwell filters, we found that primary ciliogenesis is increased in EXOC5 OE cells and inhibite

243 Although the regulation of ciliogenesis is intensively studied, how it is initiated

244 An essential component of ciliogenesis is intraflagellar transport (IFT), which is

245 o ciliary membrane cap associated with sperm ciliogenesis is made.

246 that one of the major functions of Cep164 in ciliogenesis is to recruit active TTBK2 to centrioles.

247 iated cells, but its contribution to primary ciliogenesis is unclear.

248 genesis in mice impaired neural and yolk sac ciliogenesis, leading to morphogenetic anomalies resulti

249 he centrosome is critical for cell division, ciliogenesis, membrane trafficking, and immunological sy

250 Interestingly, early during ciliogenesis, Neurl-4 transiently associated with the mo

251 criptome analyses implicate dysregulation of ciliogenesis, nuclear translocation, and an epigenetic m

252 t their regulation roles for tissue-specific ciliogenesis occur at a specific level of the TZ.

253 te that mammalian basal body replication and ciliogenesis occur independently of CETN2; however, mous

254 forkhead transcription factors important for ciliogenesis of motile cilia, cause a motile ciliopathy

255 tinct motile ciliopathy related to defective ciliogenesis of the ependymal cilia in six individuals.

256 ontrast, overexpressing Intu did not promote ciliogenesis or Hh signaling.

257 xchange factors not known to be in the Cdc42/ciliogenesis pathway and a scrambled control morpholino

258 The intracellular ciliogenesis pathway requires membrane trafficking, fusi

259 d(2) and talpid(3) mutations affect a common ciliogenesis pathway, they are caused by mutations in di

260 suggest that tuba and cdc42 act in the same ciliogenesis pathway.

261 Consideration of the different ciliogenesis pathways allows us to propose how three typ

262 These data further rationalize several ciliogenesis phenotypes of IFT mutant strains.

263 atient-derived fibroblasts displayed reduced ciliogenesis potential and abnormally elongated cilia.

264 Mutant fibroblasts were found to have normal ciliogenesis potential.

265 PCM1 null human cells show marked defects in ciliogenesis, precipitated by the loss of specific prote

266 we demonstrate that Akt regulates downstream ciliogenesis processes associated with Rab8-dependent ci

267 In summary, we show that ciliogenesis programs are conserved in the kidneys and e

268 was caused by stabilization of the negative ciliogenesis regulator CP110 and was corrected by CP110

269 mass spectrometry revealed that the primary ciliogenesis regulator, RILPL1 specifically interacts wi

270 hosphorylation of Dishevelled (DVL), another ciliogenesis regulator.

271 eases ADAMTS9 and ADAMTS20 are identified as ciliogenesis regulators that act intracellularly.

272 d cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood.

273 ed mucociliary transport caused by defective ciliogenesis, resulting in chronic airway infection.

274 Disrupting ciliogenesis results in hair follicle morphogenesis defe

275 herefore, like Dnchc2, Wdr34 is required for ciliogenesis, retrograde ciliary protein trafficking, an

276 ediating the network of interactions between ciliogenesis, signaling systems and tissue patterning.

277 ins PACSIN1 and -2 play an essential role in ciliogenesis, similar to their binding partner and membr

278 , although neither BB architecture nor early ciliogenesis steps have been described in this organism.

279 CEP83 phosphorylation is important for early ciliogenesis steps, including ciliary vesicle docking an

280 served trafficking complex, is necessary for ciliogenesis; that it is present in human urinary EVs; t

281 Before ciliogenesis, the channel becomes organized into a torus

282 TEM) tomography analysis to show that, as in ciliogenesis, the distal appendages of the CTL mother ce

283 Thus, centrin2 regulates primary ciliogenesis through controlling CP110 levels.

284 del in which the daughter centriole promotes ciliogenesis through Neurl-4-dependent regulation of CP1

285 near genes that are important in regulating ciliogenesis through the exocyst, a shuttling complex th

286 as an ancient and central role in regulating ciliogenesis throughout Eukaryota.

287 mily of transcription factors is crucial for ciliogenesis throughout evolution.

288 , we show that FSTL1 is a novel regulator of ciliogenesis thus underscoring a regulatory loop between

289 s rekindled, leading to discoveries relating ciliogenesis to autophagy and hypotheses of how molecule

290 We propose that spatial control of ciliogenesis uncouples or specifies sensory properties o

291 naling through Patched 1 (PTCH1) and primary ciliogenesis via p62/sequestosome 1 (SQSTM1).

292 FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling proce

293 Ciliogenesis was also disrupted in the mutant cells, wit

294 The effect of miR-34/449 on ciliogenesis was mediated, at least in part, by post-tra

295 -cilium protein interaction landscape during ciliogenesis, we also identify satellite proteins that s

296 ucidate the role of centriolar satellites in ciliogenesis, we deleted the gene encoding the PCM1 prot

297 the activation of Hh signaling downstream of ciliogenesis, we examined the Hh signaling pathway in mo

298 To test their role in ciliogenesis, we investigated mutant phenotypes of zebra

299 Knockdown of Dcdc2 in IMCD3 cells disrupts ciliogenesis, which is rescued by wild-type (WT) human D

300 fferentiating multiciliated cells to promote ciliogenesis without mitotic progression.