ライフサイエンスコーパス: cinnamic acid

1 rylpenta-2,4-dienoic acids (i.e., vinylogous cinnamic acids).

2 ed in 12 steps from a commercially available cinnamic acid.

3 ation of nano zeolite and foliar spraying of cinnamic acid.

4 se in phenolic acids such as gallic acid and cinnamic acid.

5 ne by using HPLC, analysing ferulic acid and cinnamic acid.

6 oside, lup-20(29)-en-3-one and 3,4-dimethoxy cinnamic acid.

7 ynthesized from commercially available trans-cinnamic acid.

8 t-catalysed oxidation of cinnamyl alcohol to cinnamic acid.

9 converts phenylalanine to ammonia and trans-cinnamic acid.

10 leaves, where it was incorporated into (11)C-cinnamic acid.

11 yl-CoA and the upstream pathway intermediate cinnamic acid.

12 primary amino acid L-phenylalanine to trans-cinnamic acid.

13 were phenolics derived from quinic and trans-cinnamic acids.

14 g phenylpropionic, benzoic, phenylacetic and cinnamic acids.

15 ct were protocatechuic, p-hydroxybenzoic and cinnamic acids.

16 gation and three different concentrations of cinnamic acid (0, 100, and 200 uM) applied topically aff

17 02 mg/g), eugenol (10.57 +/- 0.03 mg/g), and cinnamic acid (0.18 +/- 0.004 mg/g), making it superior

18 ompounds (vanillic acid, caffeic acid, trans-cinnamic acid, 2,4-dihydroxycinnamic acid, p-coumaric ac

19 Moreover, cinnamic acid (200 uM) spray combined with soil applicat

20 Quercitrin (44.54-64.68 mug/g) and cinnamic acid (27.48-31.40 mug/g) were the most abundant

21 Quercitrin (44.54-64.68 ug/g) and cinnamic acid (27.48-31.40 ug/g) were the most abundant

22 levels of the second enzyme of the pathway, cinnamic acid 4-hydroxylase (C4H), by sense or antisense

23 Cinnamic acid 4-hydroxylase (C4H), chalcone isomerase (C

24 Although the second enzyme of this pathway, cinnamic acid 4-hydroxylase (C4H), is well characterized

25 acid may occur through an enzyme complex of cinnamic acid 4-hydroxylase 1 and 2 (PtrC4H1 and PtrC4H2

26 lones, designated CYP73A9, encodes pea trans-cinnamic acid 4-hydroxylase, which catalyzes the second

27 ting xylem (SDX) of Populus trichocarpa, two cinnamic acid 4-hydroxylases (PtrC4H1 and PtrC4H2) and a

28 Cinnamic acid 4-hydroxylation is also mediated by the sa

29 acid (4), caffeic acid (5) and 3,4-dimethoxy cinnamic acid (6).

30 lated with the TMV showed high enrichment of cinnamic acids (72%), BA (34%), and SA (55%).

31 4 and VG-8) improved the bioaccessibility of cinnamic acid (86-87%), vanillic acid (87-95%), quercitr

32 aempferol (23.62mg/g) and 3-hydroxy-4-metoxy cinnamic acid (9.60mg/g).

33 Cinnamic acid amides had no inhibitory activity against

34 The parent phenol of adapalene and its (E)-cinnamic acid analogue were found to induce cancer cell

35 mic E-Z isomerization and cyclization of (E)-cinnamic acid analogues to afford coumarins.

36 ing that BD was not the intermediate between cinnamic acid and BA.

37 ut do not predict the difference between the cinnamic acid and dimethylaminocinnamic acid binding to

38 These include: cinnamic acid and its dimer 2-hydroxy-4-(4-methoxyphenyl

39 ine did not equilibrate with exogenous trans-cinnamic acid and therefore may be rapidly channeled thr

40 inic, gallic, protocatechuic, vanilic, trans-cinnamic acids and (4-hydroxyphenyl) ethanol were identi

41 t decarboxylation and cross-coupling between cinnamic acids and NH-sulfoximines has been developed.

42 ve monoacyl and three diacyl esters of trans-cinnamic acids and quinic acid were identified by ultra-

43 The chemistry of cinnamic acids and related compounds has been studied.

44 de dates presented three benzoic acids, five cinnamic acids and two flavonoids, with the predominance

45 acid and 1 mul HCCA matrix (alpha hydroxyl 4 cinnamic acid), and analysed in a Bruker Biotyper MALDI-

46 sentative compounds, including caffeic acid, cinnamic acid, and coumaric acid.

47 ly complemented by feeding with a sucrose, t-cinnamic acid, and gibberellic acid solution; presumably

48 activity, PAL activity, anthocyanin content, cinnamic acid, and p-coumaric acid in caper berries.

49 les derived sequentially from phenylalanine, cinnamic acid, and p-coumaric acid.

50 -hydroxybenzoic, p-coumaric, trans-2-hydroxy cinnamic acids, and chrysin were detected in all samples

51 concentrations of anthocyanins, phenolic and cinnamic acids, and flavonols, as well as colour compone

52 eugenol, caryophyllene, cinnamyl acetate and cinnamic acid are the major compounds found in its essen

53 Cinnamic acids are aromatic acids primarily found in pla

54 yclobutanes derived from the dimerization of cinnamic acids are the core scaffolds of many molecules

55 Coumarins, derivatives of cinnamic acid, are found in wines aged in wooden barrels

56 Pharmacological evidence implicates trans-cinnamic acid as a feedback modulator of the expression

57 HcCNL preferred cinnamic acid as a substrate but failed to activate benz

58 the calculated values for the monofunctional cinnamic acid, as well as the multifunctional coumaric a

59 hydroxybenzaldehyde, protocatechuic acid and cinnamic acid at levels of 51, 53, 1396, 13, 1138, 228 a

60 g the bioactive potential of cinnamaldehyde, cinnamic acid, benzoic acid, coumarin, linoleic acid, ol

61 Simultaneous quantitation of trans-cinnamic acid, benzoic acid, sinapic acid, and an intern

62 approach improves production efficiency in a cinnamic acid biosynthesis pathway.

63 Intermolecular hydroarylation of cinnamic acids by phenols is particularly facile, which

64 Here, we introduce cis-cinnamic acid (c-CA) as a novel and unique addition to a

65 Cinnamic acid (CA) and methyl cinnamate (MC) have attrac

66 orrelation between the production of AQs and cinnamic acid (CA), the primary precursor for IPS format

67 te transport inhibitor alpha-cyano-4-hydroxy-cinnamic acid (CHC) increased the magnitude of the acidi

68 g the MCT-4 inhibitor, alpha-cyano-4-hydroxy-cinnamic acid (CHCA), a cinnamon derivative.

69 ives (1.5-fold) increased; while benzoic and cinnamic acids, cinnamoylquinic derivatives, flavonols,

70 , p-coumaric acid (CMA), vanillin (VNL), and cinnamic acid (CNA).

71 d using 2-aminobenzothiazoles and ortho-halo cinnamic acid congeners.

72 t three stages of ripeness, anthocyanins and cinnamic acid conjugates were the compounds most affecte

73 trated that hybrid structures resulting from cinnamic acid conjugation with heterocyclic moieties fro

74 and p-coumaric, ferulic, rosmarinic, and tr-cinnamic acid contents and the methanol extract of Salvi

75 However, the level of cinnamic acid decreased on day 45 compared with day 30.

76 yphenolic compounds (benzoic acid derivates, cinnamic acid derivates, phenyl ethyl alcohols, flavones

77 ves, while caftaric acid was the predominant cinnamic acid derivative in all wines.

78 ide, catechin hexosemalonate, digallic acid, cinnamic acid derivative, and p-coumaroylmalic acid.

79 izidine-fused system, along with an embedded cinnamic acid derivative, two privileged medicinal chemi

80 from: terpenes (83), volatile phenols (30), cinnamic acid derivatives (22), norisoprenoids (21), van

81 Diels-Alder reactions, using cis- and trans-cinnamic acid derivatives (nitrile, acid, acid chloride)

82 y to afford dehydroalanines containing trans-cinnamic acid derivatives and different substituted 2-br

83 The beneficial biological effects of cinnamic acid derivatives and the lack of studies on the

84 review, an overview of the natural phenolic cinnamic acid derivatives and their plant sources (more

85 cted at 0 degrees C afforded 2-(chloromethyl)cinnamic acid derivatives as the major products and the

86 is and SAR analysis of an expanded series of cinnamic acid derivatives displaying remarkably high act

87 he hydroxylation of 4- and 3-ring carbons of cinnamic acid derivatives during monolignol biosynthesis

88 reased for 43% at optimal maturity stage and cinnamic acid derivatives for 57% compared to under-ripe

89 key reduction reactions in the conversion of cinnamic acid derivatives into monolignol building block

90 (4CL) family that converts a range of trans-cinnamic acid derivatives into the corresponding CoA thi

91 Cis/trans and anti-isomers of studied cinnamic acid derivatives may scavenge free radicals via

92 Four benzoic acid derivatives and five cinnamic acid derivatives were identified in the samples

93 hotochemical homo- and heterodimerization of cinnamic acid derivatives with the use of commercially a

94 r, the method was extended to N-viny azoles, cinnamic acid derivatives, and other unsaturated substra

95 d (HCCA) as well as five halogen-substituted cinnamic acid derivatives, including the recently introd

96 r example, the dimerization of chalcones and cinnamic acid derivatives, is a unique strategy to const

97 opposite regiochemistry can be observed for cinnamic acid derivatives, leading to the delivery of th

98 e CA activity to the corresponding 2-hydroxy-cinnamic acid derivatives, the 2-thioxocoumarin was obse

99 aceus metabolites, we identified a series of cinnamic acid derivatives, which antagonize the GLIC pro

100 rotenoids, chlorophylls, neutral lipids, and cinnamic acid derivatives.

101 enolic acids identified included benzoic and cinnamic acid derivatives.

102 le Trp alone and conjugates with benzoic and cinnamic acids did not.

103 is formed by the thermal decarboxylation of cinnamic acid during wort boiling or by enzymatic decarb

104 Syringic acid, cinnamic acid, e-viniferin, naringenin and myricetin wer

105 lained via acid triggered decarboxylation of cinnamic acid esters and subsequent inter/intramolecular

106 esis of diverse indanes starting from simple cinnamic acid esters is described.

107 ul for the synthesis of Z-2-aryl-substituted cinnamic acid esters, maintaining exclusive Z-selectivit

108 acid, tannic acid, quercetin, sinapic acid, cinnamic acid, eugenol and cinnamaldehyde) in multilevel

109 45 plant phenolics (including benzoic acids, cinnamic acids, flavonoid aglycones, C- and O-glycosides

110 A significant proportion of (3)H-trans-cinnamic acid formed from (3)H-l-phenylalanine did not e

111 Newly generated cinnamic acid from coumaric acid aglycone was detected i

112 ture of AntI in complex with CA reveals that cinnamic acid functions as a competitive inhibitor by in

113 glycosides, twenty-six dihydro-cinnamic and cinnamic acid glycosides, eleven flavanone glycosides, s

114 tions of the core BA beta-oxidative pathway (cinnamic acid --> cinnamoyl-CoA --> 3-hydroxy-3-phenylpr

115 nt optical purity, starting from inexpensive cinnamic acids, has been achieved with a novel one-pot a

116 c compounds such as some esters derived from cinnamic acid have been detected in edible oils.

117 Cinnamic acids having 3-Br, CN, NO(2), NH(2), OMe, and N

118 ysable polyphenols (gallic acid 3-O-gallate, cinnamic acid, hesperidin, myricetin 3-O-rhamnoside).

119 the histone deacetylases inhibitor LAQ824, a cinnamic acid hydroxamate, increased the acetylation of

120 CCR converts activated cinnamic acids (hydroxycinnamoyl-SCoAs) to cinnamaldehyd

121 tivum) P450 cDNAs (CYP73A9v1, encoding trans-cinnamic acid hydroxylase [t-CAH] in the core phenylprop

122 the conversion of L-phenylalanine into trans-cinnamic acid in eukaryotic and prokaryotic organisms.

123 licolor furthermore led to the production of cinnamic acid in the fermented cultures, confirming that

124 the predominant presence of ferulic acid and cinnamic acid in the millet.

125 Exogenously applied trans-cinnamic acid in the protein extracts from normal wood x

126 styrene occurs much faster and all available cinnamic acid in wort was converted completely within a

127 rts of palladium-catalyzed hydroarylation of cinnamic acids in trifluoroacetic acid are erroneous.

128 esis negatively affects catalytic rates with cinnamic acid, indicating a direct link between enzyme-i

129 The in silico study showed that trans-cinnamic acid interacts with target proteins such as NF-

130 The measured GA for cinnamic acid is 334.5 +/- 2.0 kcal/mol.

131 tive deamination of l-phenylalanine to trans-cinnamic acid, is ubiquitously distributed in plants.

132 ustrate metabolic changes in salicylic acid, cinnamic acid, jasmonic acid, indole-3-acetic acid, absc

133 lows the heterodimerization of two different cinnamic acids, leading to unsymmetrical B-truxinic acid

134 ography (HPLC) was used for determination of cinnamic acid markers, the total phenolic content (TPC)

135 The phenylpropanoid 3,4-(methylenedioxy)cinnamic acid (MDCA) is a plant-derived compound first e

136 s the photodimerization of substituted trans-cinnamic acid methyl esters in water.

137 diation of the host-guest complexes of trans-cinnamic acid methyl esters with the Pd nanocage resulte

138 The implications of this cinnamic acid-modulated effect on 4CL enzyme activities

139 HPLC analysis revealed gallic acid, trans-cinnamic acid, p-coumaric acid, and ferulic acid as the

140 Benzyl alcohol, cinnamyl alcohol, cinnamic acid, p-tolylacetic acid and 4-hydoxycinnamic a

141 iacol, known as volatile phenols (VPs), from cinnamic acid precursors.

142 e AtPAL-catalyzed hydroamination reaction of cinnamic acids provided several unnatural amino acids of

143 Flavonoids, like (+)-catechin, cinnamic acids, quercetin glycosides were identified.

144 e propose that metabolic channeling of trans-cinnamic acid requires the close association of specific

145 ic acid, gallic acid, p-hydroxybenzoic acid, cinnamic acid, rosmarinic acid, p-coumaric acid, m-couma

146 licylic acid, kaemferol-3-O-glucoside, trans-cinnamic acid, rutin, scopoletin, l-phenylalanine, 4-cou

147 rthermore, the SA metabolites phenylalanine, cinnamic acid, salicyloyl-glucose, and catechol are also

148 Benzoic acid and cinnamic acid series inhibitors showed relatively weak i

149 were compared with those for chlorogenic and cinnamic acids (the main bioactive constituents of the s

150 he non-oxidative deamination of Phe to trans-cinnamic acid, the committed step for the major pathway

151 , a P450 that catalyzes the hydroxylation of cinnamic acid three steps earlier in the general phenylp

152 tabolism formed via decarboxylation of trans-cinnamic acid to benzoic acid and its subsequent 2-hydro

153 igase OSD1 catalyses the conversion of trans-cinnamic acid to cinnamoyl-CoA, which is subsequently tr

154 ase as a donor of electrons and hydroxylates cinnamic acid to form 4-coumaric acid in phenylpropanoid

155 gallic acid, sinapic acid, p-coumaric acid, cinnamic acid, trans-fereulic acid, syringic acid, chlor

156 is only able to couple (de)carboxylation of cinnamic acid-type compounds to reversible 1,3-dipolar c

157 plished via decarboxylative sulfonylation of cinnamic acids using sulfonylazides, p-toluenesulfonylme

158 key bioactives (cinnamaldehyde, eugenol, and cinnamic acid) using two extraction methods: accelerated

159 derivatives of styrene, stilbene, chalcone, cinnamic acid, various fused carbo- and heterocycles, et

160 f hydroxyl groups and a carboxyl group makes cinnamic acids very hydrophilic, preventing them from cr

161 mon chemicals, benzaldehyde, allylamine, and cinnamic acid, via intramolectular [2+2]-photochemical c

162 The upstream accumulation in cis-cinnamic acid was found to be likely to cause polar AUX

163 Cinnamic acid was found to be the most potent compound r

164 By means of labelling experiments, (E)-cinnamic acid was identified as the precursor of 3-pheny

165 Such compartmentalization of trans-cinnamic acid was not observed after elicitation or in c

166 mmonia lyase (PEG-PAL) metabolizing Phe into cinnamic acid was recently approved as treatment for PKU

167 of which 2,4-dihydroxybenzoic acid and trans-cinnamic acid were dominant in these fruits with concent

168 p-Hydroxybenzoic, p-coumaric and cinnamic acids were identified in the extract obtained w

169 Caffeic and cinnamic acids were identified through high-pressure liq

170 enzoic, vanillic, protocatechuic, gallic and cinnamic acids were the main contributors in bound fract

171 id and rutin) and roots (p-coumaric acid and cinnamic acid) were higher at 15 degrees C.

172 pcorn C exhibited a higher peak intensity of cinnamic acid, whereas Popcorn 5 contained more caffeic

173 sulfur-mediated decarboxylative coupling of cinnamic acids with amines via oxidative cleavage of the

174 via the metal-free oxidative cyclization of cinnamic acids with arylhydrazines.

175 Phenolic cinnamic acids, with one or more hydroxyl groups in the