ライフサイエンスコーパス: cisternal

1 ed perspective, we propose a model, based on cisternal adhesion and cisternal maturation as the two c

2 stacking might have occurred using only weak cisternal adhesive processes because of the differential

3 binding protein domains that are attached to cisternal adhesive proteins allows mitochondria to invad

4 When isolated from the cisternal and protein body ER, the PDI protein resolves

5 ha-zein and the 27-kD gamma-zein proteins on cisternal and protein body rough endoplasmic reticulum m

6 The endoplasmic reticulum (ER) contains both cisternal and reticular elements in one contiguous struc

7 rain compression was calculated by using the cisternal angle (the angle formed at the intersection of

8 Cisternal angle is an objective measure of midbrain comp

9 The presence of a cisternal angle less than 25 degrees (indicating severe

10 dure midbrain compression, as indicated by a cisternal angle of less than 25 degrees , which was sign

11 The cisternal angle was measured in 100 control subjects wit

12 xon signed rank test was used to compare the cisternal angles ipsilateral and contralateral to the tu

13 , including 136 new additions, with over 180 cisternal assignments.

14 l change in response to depletion of nuclear cisternal Ca2+ levels.

15 disease, in which surgical implantation of a cisternal catheter allowed bacterial instillation and ce

16 D-reared subjects demonstrated elevations of cisternal cerebrospinal fluid (CSF) corticotropin-releas

17 Cisternal cerebrospinal fluid (CSF) levels of FGLs corre

18 er a 4-year period after obtaining blood and cisternal cerebrospinal fluid (CSF) samples from 49 free

19 d ellipsoid method applied across five major cisternal compartments on non-contrast CT.

20 zyme to be present throughout the subsurface cisternal complex (SSC), especially near the innermost l

21 obility within ER membranes, indicating that cisternal connectivity was not disrupted.

22 in the Golgi membranes without forming cross-cisternal contacts between enzyme molecules residing in

23 The net result is that cisternal cores remain stacked, but cisternal diameter i

24 connected laterally from each other, and the cisternal cross-sectional diameters are significantly re

25 bulization, we observed a linear increase in cisternal CSF AVP levels, and a quadratic rise and fall

26 aily temporal pattern of hypocretin-1 in the cisternal CSF of the squirrel monkey, a New World primat

27 er 2 h, 36.9+/-4.6% 125I-T4 was recovered in cisternal CSF.

28 is that cisternal cores remain stacked, but cisternal diameter is reduced by rim consumption.

29 separate Golgi cisternae has meant that the cisternal distribution of most resident proteins, and th

30 ally from the stack and are continuous with "cisternal" domains that maintain normal thickness and al

31 whether the ER becomes more tubular or more cisternal during mitosis is controversial, and dedicated

32 hemorrhage/subarachnoid hemorrhage, complete cisternal effacement, and absence of contusion.

33 the Golgi complex into juxtanuclear, stacked cisternal elements.

34 han the rest of the endocytic pathway, early cisternal endosomes, spherical late endosomes, late endo

35 ins in the endocytic pathway up to the early cisternal endosomes.

36 pha-globulin RNAs are not distributed to the cisternal ER as expected for a PSV-localized protein, bu

37 Mis-targeting of alpha-globulin RNAs to the cisternal ER dramatically alters the spatial arrangement

38 increase of PDI in fl2 occurs mainly in the cisternal ER fraction, whereas the most dramatic increas

39 rter RNA redirects its localization from the cisternal ER to the protein body ER.

40 reticulum (ER), the protein body ER and the cisternal ER, in developing rice seeds.

41 , however, redirects RNA localization to the cisternal ER.

42 ), whereas glutelin RNAs are targeted to the cisternal ER.

43 protein body endoplasmic reticulum (ER) and cisternal ER.

44 A splicing and cytosolic localization to the cisternal-ER.

45 h is required for proper RNA localization to cisternal-ER.

46 hanges in their structure, with increases in cisternal fenestration and tubulation.

47 le accumulation, and GMAP210 loss leading to cisternal fragmentation, dilation, and the accumulation

48 e, these GM130 and GRASP65-dependent lateral cisternal-fusion reactions are necessary to achieve unif

49 ac1 cycles between endoplasmic reticulum and cisternal Golgi compartments.

50 hysiological role of the extensively studied cisternal Golgi rab protein, rab6, is modulation of Golg

51 Furthermore, cisternal hematoma volume correlated with HO-1 activity

52 t pups at postnatal day (P)2-3 with an intra-cisternal injection of 5,7-dihydroxytryptamine (5,7-DHT;

53 Moreover, intra-cisternal injection of antibody against CCL21 hampered s

54 Cisternal injection of murine melanoma cell lines succes

55 gue-Dawley rats had hydrocephalus induced by cisternal kaolin injection.

56 the Golgi is resolving Golgi proteins at the cisternal level under light microscopy.

57 ed in regard to route of administration (ie, cisternal, lumbar, ventricular).

58 We measured ALLO content in four cisternal-lumbar fractions of cerebrospinal fluid (CSF)

59 The cisternal lumen averaged 18 nm so that the cisternal vol

60 lasma membrane, and the average width of the cisternal lumen were recorded.

61 ion of adenosine triphosphate, but not intra-cisternal magna injection of adenosine in mice model.

62 he responses to whisker stimulation or intra-cisternal magna injection of adenosine triphosphate, but

63 x9 mutant lacked this expansion for both the cisternal margins and the TGN, whereas Golgi stack proli

64 e xylan product accumulated in swollen trans cisternal margins and the Trans-Golgi network (TGN).

65 Following nocodazole removal, all cisternal markers accumulated at the same rate in a juxt

66 Our findings rationalize the logic of cisternal maturation and explain how COPI can engage dif

67 ose a model, based on cisternal adhesion and cisternal maturation as the two core principles, illustr

68 rough the secretory pathway, suggesting that cisternal maturation can account for the kinetics of sec

69 Golgi cisternal maturation has been visualized by fluorescence

70 According to the cisternal maturation hypothesis, endoplasmic reticulum (

71 veal that COPI tubular transport complements cisternal maturation in explaining how anterograde Golgi

72 Our findings suggest that cisternal maturation involves a COPI-dependent pathway t

73 In our analysis cisternal maturation is a robust consequence of vesicle

74 The rate of cisternal maturation matches the rate of protein transpo

75 The results support the cisternal maturation mechanism.

76 This motif precisely matches the cisternal maturation model of the Golgi, which was devel

77 e through bi-directional vesicles, while the cisternal maturation model postulates that transient cis

78 The cisternal maturation model predicts that each cisterna i

79 The cisternal maturation model proposes that secretory prote

80 late Golgi cisternae is consistent with the cisternal maturation model.

81 given to endoplasmic reticulum (ER)-derived, cisternal maturation models of Golgi assembly while in m

82 or COPI-independent intra-Golgi transport by cisternal maturation with a shift in mechanism to antero

83 in the same cisterna, whereas, according to cisternal maturation, Golgi residents recycle from dista

84 intra-Golgi recycling late in the process of cisternal maturation.

85 secretion of certain proteins and for Golgi cisternal maturation.

86 by the movement of Golgi cisternae, known as cisternal maturation.

87 Cisternal membrane fusion requires two AAA ATPases, p97

88 thought to multiply span the subrhabdomeric cisternal membrane.

89 perature shift, exaggerated stacks of curved cisternal membranes (aberrant endosome) also accumulated

90 ms that (i) facilitate the fusion/fission of cisternal membranes and control the directionality and s

91 The Golgi apparatus is comprised of stacked cisternal membranes forming subcompartments specialized

92 Direct fusion of ER/Golgi intermediates with cisternal membranes of the Golgi stack was not observed

93 ly, H(2)O(2) treatment reduced the number of cisternal membranes per Golgi stack, suggesting a loss o

94 these spherical particles were wrapped with cisternal membranes, analogous to intracellular and extr

95 und in vesicles that could be separated from cisternal membranes.

96 and over-expression of ER tubule-shaping and cisternal-modifying proteins.

97 s places functional constraints on the Golgi cisternal number and enzyme specificity.

98 gi trafficking, induces an increase in Golgi cisternal number in HeLa cells and delays the cell surfa

99 Golgi ribbon from one side to the other via cisternal openings.

100 pine apparatus of neuronal dendrites and the cisternal organelle of axonal initial segments.

101 s, also colocalizes with synaptopodin on the cisternal organelle, a peculiar stack of ER cisterns res

102 ergo homeostatic plasticity, contains lesser cisternal organelles, and receives fewer inhibitory inpu

103 Kv2.1 clustering on the AIS are sites where cisternal organelles, specialized intracellular calcium

104 maintained their juxtanuclear localization, cisternal organization and are competent for the anterog

105 d a side-averaging approach to visualize the cisternal organization and intra-Golgi transport in noco

106 ickness, membrane structure, cargo staining, cisternal origin, and spatial distribution.

107 f beta-endorphin, we conducted a ventricular-cisternal perfusion with artificial cerebrospinal fluid

108 cerebellar artery and commonly involves the cisternal portion with mild to moderate severity.

109 subject of intense debate, with two models, cisternal progression and intercisternal exchange, emerg

110 The cisternal progression and the stable compartment models

111 vations on protein transport cannot rule out cisternal progression as contributing significantly to t

112 ith addressing this question in yeast, where cisternal progression has been extensively studied.

113 However, there is very limited evidence that cisternal progression is regulated, and no evidence for

114 refore, our findings challenge the classical cisternal progression model and suggest the stable compa

115 zed cisternal proliferation fits best with a cisternal progression model of Golgi function.

116 Classic cisternal progression model posits that both the intra-G

117 mbrane cargoes and directly demonstrated the cisternal progression of cargoes from the cis- to the tr

118 in the rapid transport of aggregates without cisternal progression on this time scale.

119 nges in Ypt1 and Ypt31 activity affect Golgi cisternal progression, early-to-transitional and transit

120 prevailing view of intra-Golgi transport is cisternal progression, which has a key prediction--that

121 GTPases regulate two separate steps of Golgi cisternal progression.

122 ae via retrograde carriers in synchrony with cisternal progression.

123 n sorting compartment of the cell-occurs via cisternal progression/maturation and that Ypt/Rab GTPase

124 occur at a constant velocity dictated by the cisternal progression; furthermore, COPI-mediated intra-

125 that the observed correlation with localized cisternal proliferation fits best with a cisternal progr

126 Accumulation of cisternal proteins in scattered Golgi elements was not b

127 ospinal fluid (CSF) samples were obtained by cisternal puncture.

128 ab6a', and rab33b, the most commonly studied cisternal rab proteins.

129 We conclude that Golgi cisternal rabs, and in particular rab6a, are regulators

130 The ER in rtn1Delta cells is predominantly cisternal rather than reticular, yet the net surface are

131 p97-mediated cisternal regrowth is p115-independent, but we now demon

132 NSF-mediated cisternal regrowth requires a vesicle tethering protein,

133 reconstructs these events has revealed that cisternal regrowth requires interplay between soluble fa

134 emplate for postmitotic Golgi reassembly and cisternal remodeling.

135 ible fragmentation through unstacking of the cisternal ribbon and disassembly into radially dispersed

136 sent in the Golgi apparatus was localized to cisternal rims and peri-Golgi vesicles exclusively.

137 Toxoplasma Rab6 was localized to cisternal rims of the late Golgi and trans-Golgi network

138 radiographic model SAHV that measures basal cisternal SAH blood volume using a derivation of the ABC

139 bles accurate identification of the proximal cisternal segment of the trochlear nerve and its neurova

140 3D CISS MR imaging depicted the proximal cisternal segment of the trochlear nerve in the transver

141 trast resolution imaging acquisitions of the cisternal segments of the trigeminal nerves and vessels.

142 ly rearing was associated with elevations of cisternal somatostatin and of serotonin and dopamine met

143 Large extracellular cisternal spaces were visible between overlapping AG cel

144 fects are linked and might be explained by a cisternal-specific delay in cargo transport.

145 SP65 is required in assays that reconstitute cisternal stacking and vesicle tethering.

146 esive energy gluing cisternae dictates Golgi cisternal stacking, irrespective of which molecules medi

147 vesicle transport, cisternae formation, and cisternal stacking.

148 organelles with improved ribbon linking and cisternal stacking.

149 lar H+-ATPase is associated with this cupped cisternal structure, indicating that it corresponds to t

150 bbon is to create synaptic vesicles from the cisternal structures that are abundant at the base of ha

151 The large cisternal structures were attached to the ribbon by fila

152 rge and numerous unanticipated intercellular cisternal structures, defines the magnitude of stratum c

153 nstrate a profound structural disruption and cisternal swelling of the Golgi apparatus (GA) in the co

154 Similarly structured cisternal synapses mediate cholinergic inhibition of coc

155 ne the ultrastructure of genetically altered cisternal synapses.

156 C (cisternal) synapses with a near membrane postsynaptic ci

157 human disease was established using a blind cisternal tap technique to inoculate 4 x 10(3)-1 x 10(6)

158 to commence by laying down and compacting a cisternal tongue against the inside of the axolemma.

159 the number and specificity of enzymes, inter-cisternal transfer rates, and number of cisternae provid

160 he CNS following intracerebroventricular and cisternal transplantation in neonatal mice.

161 NAc from the medial to trans-Golgi via inter-cisternal tubules.

162 ading to a loss of Golgi membrane tethering, cisternal unlinking, and Golgi breakdown.

163 of GRASP65 oligomerization and causes Golgi cisternal unstacking.

164 During in vivo ventriculo-cisternal (V-C) perfusion in the anesthetized rabbit (me

165 e cisternal lumen averaged 18 nm so that the cisternal volume was approximately 30% larger than that

166 e those of wild-type littermates except that cisternal volumes were significantly larger.