ライフサイエンスコーパス: classically

1 GFRs) and G protein-coupled receptors, which classically activate distinct intracellular signaling pa

2 BAR501 shifted intestinal macrophages from a classically activated (CD11b(+), CCR7(+), F4/80(-)) to a

3 ossess higher phagocytic activities and that classically activated (M1) macrophages exhibit greater p

4 , locally proliferating macrophages were not classically activated (M1), but they exhibited a rather

5 increased infiltration and proinflammatory (classically activated [M1]) polarization of macrophages

6 STAT3 is a transcription factor classically activated by specific tyrosine 705 phosphory

7 cific 6 and Protein S, were downregulated in classically activated cells.

8 hubs of the Default Mode Network, a network classically activated during resting state.

9 in increased number and distribution of both classically activated inflammatory macrophages and cytot

10 est that cadmium mediates the persistence of classically activated lung macrophages to exacerbate lun

11 c cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose

12 most well-defined macrophage subsets are the classically activated macrophages (CAM s) and the IL-4-d

13 macrophages while leaving the generation of classically activated macrophages (M1) intact.

14 ifferent macrophage phenotypes classified as classically activated macrophages and alternatively acti

15 R1 gene ablation enhanced the recruitment of classically activated macrophages in the colonic lamina

16 for the diverse macrophage functions, these classically activated macrophages show metabolic reprogr

17 ulated the Th1-stimulatory cytokine IL-12 in classically activated macrophages, whereas in alternativ

18 strocytes, which we termed A1, is induced by classically activated neuroinflammatory microglia.

19 tle is known about the relative roles of M1 (classically activated or polarized) and M2 (alternativel

20 macrophages polarize to a pro-inflammatory, classically activated phenotype after cadmium-mediated l

21 altered the macrophage phenotype, promoting classically activated polarization.

22 ing basal conditions and markedly reduced in classically activated polarized cells.

23 nflammatory phenotype with reductions of the classically activated pro- and anti-inflammatory markers

24 various liver diseases and is controlled by classically activated pro-inflammatory macrophages, whil

25 Galpha(i2) signaling) have a tendency toward classically activated proinflammatory (M1) phenotype, Gn

26 In classically activated proinflammatory M1-like MDM, howev

27 PS) polarizes macrophages toward the M1, or "classically activated" phenotype that participates in de

28 )).Measurements and Main Results: "M1-like" (classically activated) and proinflammatory gene sets suc

29 ted with a high ratio of proinflammatory M1 (classically activated) macrophages to anti-inflammatory

30 s of circulating chromogranin A (CgA, CHGA), classically an antiangiogenic protein, can activate late

31 are well-characterized hallmark molecules of classically and alternatively activated macrophages, res

32 ls (TR-Mphi) and two for their polarization (classically and alternatively activated macrophages: M1

33 We found that both in classically and alternatively polarized macrophages, NFA

34 Both classically and non-classically restricted cytotoxic CD8

35 Phenotypic differences between classically and nonclassically affected patients are evi

36 The definition of severe aortic stenosis has classically and retrospectively been based on the natura

37 ctronics when the radiation field is treated classically, and that differences between the toolboxes

38 Classically, animal cells nucleate or form new microtubu

39 TOT classically antagonizes estradiol (E2) -dependent breast

40 virus uses this same activity to redirect a classically antiviral protein into a proviral effector.

41 HG that treat the driving and emitted fields classically are usually very successful but inherently c

42 form of short-chain fatty acid (SCFA), acts classically as a potent anti-angiogenic agent in tumour

43 Analysis of proteins classically assigned as hepatic markers demonstrated tre

44 e adenosine hypothesis of schizophrenia, the classically associated hyperdopaminergic state may be se

45 he obvious cognitive/behavioral interruption classically associated with absence seizures or CPSs in

46 The coupling between PGO waves and ripples, classically associated with distinct sleep stages, suppo

47 largely unknown, particularly in cancers not classically associated with homologous recombination def

48 lung, eye, and brain diseases of prematurity classically associated with hypoxic insults.

49 on and remodeling beyond the type 2 response classically associated with IL-33 signaling.

50 gh levels of glycosylation profiles that are classically associated with immature intracellular prote

51 ndependent of metabolic or signaling changes classically associated with increased lysosomal pH, unco

52 nteractions and into how components that are classically associated with inflammation can differentia

53 Mutations in CLN3 are classically associated with juvenile neuronal ceroid lip

54 The D. gyrociliatus genome retains traits classically associated with larger and slower-evolving g

55 h which we can understand how a brain region classically associated with motor control, the cerebellu

56 s continue to be recruited, but that regions classically associated with place perception are additio

57 xhibit properties intermediate between those classically associated with PV+ or SST+ CINs, which may

58 Surprisingly, while high p21 expression is classically associated with senescence, we find the oppo

59 Host-parasite theory has classically assumed fluctuations either occur between hi

60 While spectral opponency in a primate RGC is classically assumed to contribute to hue perception, a r

61 AMPs have been classically assumed to have broad-spectrum activity and

62 Surprisingly, although D2Rs are classically assumed to signal through Gi/o-coupled G-pro

63 This operation is classically attributed to an increase in GABAergic synap

64 atric and cognitive deficits with the latter classically attributed to disruption of frontostriatal n

65 jor shifts in silk functional properties are classically attributed to innovations in silk genes and

66 PHH is classically attributed to primary impairments in CSF rea

67 talytic asymmetric reactions involving these classically avoided strained intermediates.

68 ressed conditions such as rest, hemodynamics classically become abnormal during stressors such as exe

69 han the Gi/o-associated mechanisms that have classically been ascribed to D2Rs.SIGNIFICANCE STATEMENT

70 Peripheral components of the ER have classically been described as comprising both tubules an

71 IL-10 has classically been designated an immunosuppressive cytokin

72 he terrestrial realm, resource depletion has classically been related to accessibility through road n

73 Variants in ion channel genes have classically been studied in low throughput by patch clam

74 l protein without catalytic function and has classically been termed as pseudo-enzymes.

75 owing due to illumination, and has therefore classically been thought of as an adaptation for visual

76 Neuroplasticity has classically been understood to arise through changes in

77 ensitivities below the limits established by classically behaving states(1,2).

78 Although NCX Na(+)/Ca(2+) exchangers are classically believed to operate only at the plasma membr

79 Classically, bloom response to horizontal stirring is re

80 y (SD) is a mucohemorrhagic colitis of swine classically caused by infection with the intestinal spir

81 nal cell carcinoma, even in tumors that were classically CD8(+) T cell inflamed.

82 urotoxic syndrome of cerebral vasoregulation classically characterized by bilaterally symmetrical par

83 me is a rare, recessively inherited disorder classically characterized by high myopia, retinal detach

84 Classically Class IB phosphoinositide 3-kinase (PI3Kgamm

85 Classically closo-carborane anions, particularly [HCB(11

86 advantage, we prove, is unrealizable in any classically commuting theory.

87 eters are iterated to self-consistency via a classically computed feedback loop where quantum gate er

88 pants' pain ratings (social information) and classically conditioned pain-predictive cues before expe

89 Classically considered "nonenveloped," recent studies sh

90 of the innate immune system, neutrophils are classically considered a homogenous population of termin

91 Keratoconus (KC) is classically considered a non-inflammatory condition caus

92 ese studies demonstrate that amides, despite classically considered inert substrates, can be harnesse

93 low-level visual discriminations [1] and is classically considered outside of neural systems that su

94 Classically considered short-lived and purely defensive

95 Gq signaling in cardiac myocytes is classically considered toxic.

96 ressor phosphatase and tensin homolog (PTEN) classically counteracts the PI3K/AKT/mTOR signaling casc

97 zed that SWDs are not always associated with classically defined absence seizures or CPSs.

98 Carvedilol, classically defined as a betaAR antagonist, is widely us

99 nflammation and contributes to cholera being classically defined as a noninflammatory diarrheal disea

100 CXCL5 is classically defined as a proinflammatory chemokine, but

101 d the behaviors generated, occurs beyond the classically defined auditory system, in limbic or associ

102 interval and occurred even in the absence of classically defined bursts.

103 Pulmonary sarcoidosis is classically defined by T-helper (Th) cell type 1 inflamm

104 e nucleus, like all thalamic nuclei, has two classically defined categories of spikes-tonic and burst

105 Those with classically defined CB or SGRQ defined CB had a greater

106 Ihog spatial discontinuity may contribute to classically defined cell segregation and lineage restric

107 Chemogenetic inactivation of two classically defined cell types, the wide-field (WF) and

108 genes and became demethylated at the loci of classically defined effector molecules.

109 Thus, classically defined HSCs maintain immune cell developmen

110 maximal flux is different compared with the classically defined kcat.

111 We first confirm XMAP215 as a classically defined nucleator that reduces the nucleatio

112 suggests increasingly complex coupling among classically defined pathways.

113 Although oscillation-based FC is classically defined relative to a prestimulus baseline,

114 Our findings describe CHD4, a classically defined repressor, as positive regulator of

115 essing related to protective coding and that classically defined taste neurons contribute to this pro

116 d and can be measured even in the absence of classically defined thalamic bursts.

117 on prevention and control guidelines between classically-defined airborne and droplet precautions.

118 re, causing Streptomyces to deviate from its classically-defined life cycle.

119 finding that circadian period defects in two classically derived Neurospora clock mutants each arise

120 Botulism is classically described as a bilateral, symmetric, descend

121 Glucagon is classically described as a counterregulatory hormone tha

122 sferase 1 (NAT1), present in all tissues, is classically described as a phase-II xenobiotic metaboliz

123 class II (MHC II)-CD4 immunologic synapse is classically described between the T-cell receptor of CD4

124 ctivated and transcriptionally distinct from classically described cytotoxic CD4(+) memory T cells th

125 ng with dermal hyperneury, cutaneous lesions classically described in MEN 2B syndrome, and 1 relative

126 Chronic actinic dermatitis (CAD) is classically described in older, white men, although incr

127 through cell-to-cell contact rather than the classically described quorum-sensing mechanism.

128 The classically described role of the KDEL receptor is to re

129 on collaterals and more generally to that of classically described STN neurons.

130 lls that expressed pro-surfactant protein C, classically described to be expressed only by AT2 cells.

131 extended to include strains other than those classically described.

132 Small molecules have been classically developed to inhibit enzyme activity; howeve

133 The skin eruptions are classically diffuse, symmetric maculopapular rashes invo

134 Classically, diversity has been attributed to cells sens

135 lapping symptomatology, nomenclature and are classically divided into categorical subtypes.

136 Tuberculosis is classically divided into states of latent infection and

137 Classically, division axis specification involves centro

138 Classically, DL models utilize large volumes of training

139 Classically, during viral infection, the presence of for

140 alized or systemic allergic reaction that is classically elicited by antigen crosslinking of antigen-

141 Classically, Epac1 is thought to exert its effects throu

142 e variability of the MLE is far greater than classically estimated, and (iii) the likelihood-ratio te

143 displays intermediate features lying between classically excitatory and inhibitory endings; and (3) i

144 ed protein 4 (CTLA-4; an inhibitory molecule classically expressed on T cells) is now reported at an

145 s.SIGNIFICANCE STATEMENT Parkinson's disease classically first becomes manifest in one hemibody befor

146 This allows the classically forbidden transitions from the ground-state

147 ses about the origin of eukaryotic cells are classically framed within the context of a universal 'tr

148 Classically, G protein-coupled receptor (GPCR) stimulati

149 Classically, G-protein-coupled receptors (GPCRs) are tho

150 omenon, known as glomerular hyperfiltration, classically has been hypothesized to predispose to irrev

151 The mast cell-nerve unit classically has represented a fundamental neuroimmune ax

152 Classically, hormones elicit specific cellular responses

153 Two basal ganglia pathways have been classically hypothesized to regulate this process via op

154 The process of adaptive radiation was classically hypothesized to require isolation of a linea

155 Models of speech recalibration classically ignore this volatility.

156 ancreatic ductal adenocarcinomas (PDACs) are classically immunologically cold tumors that have failed

157 gnificant induction of proinflammatory genes classically implicated in primate filoviral pathogenesis

158 alize interest in this formalism by allowing classically impossible calculations to be performed.

159 The possibility of performing tasks that are classically impossible has made quantum entanglement a p

160 c actinobacterium Tropheryma whipplei occurs classically in the gastrointestinal tract and shows hist

161 ese subgroups roughly overlap with what were classically indicated as regular and bursting cells, and

162 and interferon regulatory factor 3 (IRF-3), classically inducing IFNbeta production.

163 hysical constraints frame the -1/4 power law classically inferred from allometry of animal metabolic

164 Metformin-dependent activation of AMPK classically inhibits mTORC1 via TSC/RHEB, but several li

165 ere central, deep or large, non-Nocardia, or classically invasive Pseudomonas aeruginosa; for patient

166 ough the investigation of oral tolerance has classically involved Ag feeding, we have found that oral

167 The Galphas subunit is classically involved in the signal transduction of G pro

168 the precuneus and temporoparietal junction, classically involved in ToM in adults.

169 linical entity from epiretinal membrane that classically is associated with lamellar macular holes, b

170 Classically it presents after 30 weeks gestation with no

171 s sandwiched between the electrodes, whereas classically it should be unchanged.

172 Classically, it has been hypothesized that reach-to-gras

173 Classically, it was thought that analgesic tolerance to

174 complement membrane attack complex (MAC) is classically known as a cytolytic effector of innate and

175 amounts of cysteinyl leukotrienes (cysLTs), classically known as a slow reactive substance of anaphy

176 We posit that upstream regulatory proteins, classically known as pattern-recognition receptors, oper

177 The E2F family, classically known for a central role in cell cycle, has

178 R (PKR) is another host non-self RNA sensor classically known for its vRNA recognition activity.

179 ented independently by the G protein complex classically known for orienting the mitotic spindle.

180 esses and demonstrate that multiple pathways classically known to be involved in embryonic developmen

181 urfaces, interfaces and grain boundaries are classically known to be sinks of defects generated withi

182 RNA has been classically known to play central roles in biology, incl

183 In the current study we show that this classically limbic area directly controls motor behavior

184 Disinhibition of this classically limbic territory leads to profound motor cha

185 Early loss of vision is classically linked to large-scale cross-modal plasticity

186 The endoplasmic reticulum (ER) is classically linked to metabolic homeostasis via the acti

187 elicits activation of neural representations classically linked to places when this geographic knowle

188 cocaine-induced synaptic changes in neurons classically linked with aversion.

189 Although being classically located inside the liver parenchyma, hemangi

190 egeneration of stereochemistry" methods, are classically made by only moderately diastereoselective m

191 reted rather narrowly in the literature when classically measured in one-dimension.

192 Their binding properties are classically measured in solution and characterized by an

193 Anaphylaxis is classically mediated by allergen cross-linking of IgE bo

194 Thus, instead of classically mediating the kinase arm, PI3Kgamma inhibits

195 st responses were identified as conventional classically MHC I restricted, and we found no evidence f

196 Surprisingly, we find that the classically microtubule-associated Pavarotti binds direc

197 difficult in the case of amyloidosis, which classically mimics HCM.

198 Tumor growth curves are classically modeled by means of ordinary differential eq

199 aerobiales and the Negativicutes, within the classically monoderm Firmicutes has blurred the monoderm

200 icutes and the Halanaerobiales belong to the classically monoderm Firmicutes, but possess outer membr

201 Classically, natural killer (NK) cells have been defined

202 Classically, NRs are targeted via their hydrophobic, ort

203 receptor activation (SARA, zfyve9) has been classically observed in early endosomes of different cel

204 ctions occur via an associative mechanism as classically observed with transition metal complexes.

205 Cutaneous T cell-mediated reactions classically occur more than 6 hours after drug administr

206 Classically one expects an AFM tip interacting with a ce

207 and is hardware-dominant relying on only one classically optimized parameter.

208 T helper polarization is classically orientated by dendritic cells (DCs), which a

209 Classically, our understanding of itch mechanisms has ce

210 Classically, P(open) is regulated by a calcium-sensitive

211 Though mechanical characterization is classically performed during loading, the unloading (rec

212 Classically, phenotype is what is observed, and genotype

213 ories involves the additional recruitment of classically place-selective parahippocampal gyrus, retro

214 namics are more nuanced and interactive than classically predicted by RLT.

215 We show that crystals grow non-classically, predominantly by incorporation of centrosym

216 It classically presents as chronic diarrhea, bloating, and

217 Mumps is an acute viral illness that classically presents with parotitis.

218 y remarkable plasticity in switching between classically (pro-inflammatory-M1) and alternatively acti

219 eptide, a potent stimulator of ion secretion classically produced by enteric neurons.

220 ESCC classically progresses rapidly and frequently causes mor

221 Classically, PxD have been categorised according to thei

222 T cells are classically recognized as distinct subsets that express

223 strate that encodes color signals beyond the classically recognized L versus M and S versus L+M cardi

224 r influenza A virus evolution, including its classically recognized role in the emergence of genetica

225 emic hyporesponsiveness to dietary antigens, classically referred to as oral tolerance, comprises a d

226 Mac-1 (CD11b/CD18) is a beta2 integrin classically regarded as a pro-inflammatory molecule beca

227 extracellular matrix protein tropoelastin is classically regarded as a structural component that conf

228 DNA-associated proteins (DAPs) classically regulate gene expression by binding to regul

229 tion of individual genes, a process that has classically relied on characterizing single mutations.

230 the alpha-position of carbonyl compounds has classically relied on enolate chemistry.

231 assessment and imaging of the notochord has classically relied on histological techniques, which int

232 Studying posttranslational modifications classically relies on experimental strategies that overs

233 Cryptosporidiosis is classically reported in patients with acquired immunodef

234 rs where multiple antennas and receivers are classically required.

235 ion with squaraines and cyanines relative to classically researched indoline donor analogues.

236 Pancreatic ductal adenocarcinoma (PDA) is classically resistant to immunotherapy and lacks baselin

237 Classically responsive and non-classically responsive ce

238 Classically responsive and non-classically responsive cells contained significant infor

239 x than auditory cortex, via ensembles of non-classically responsive cells coordinating the behavioral

240 These non-classically responsive neurons are difficult to interpre

241 Rh185 generated Gag-specific CD8(+) T cells classically restricted by MHC-Ia but not MHC-E.

242 Both classically and non-classically restricted cytotoxic CD8(+) T cells are impo

243 Toxicity classically results from inhalational exposures in indiv

244 has been reported to inhibit the release of classically secreted cytokines such as TNF.

245 hodology, will expedite the discovery of non-classically secreted effector proteins in Gram-positive

246 Myxomatous mitral valve with prolapse are classically seen with abnormal leaflet apposition during

247 Classically, serum ferritin and liver biopsy have been u

248 Janus kinases (JAKs) classically signal by activating STAT transcription fact

249 Classically, solutes are modeled using reaction-advectio

250 Classically solving a general set of polynomial equation

251 Classically, specific orbitofrontal cortex (OFC) neurons

252 there has been a long-standing view that the classically spliced form of EAAT5 is not abundant or wid

253 Polyamines are classically studied as regulators of ion channel gating

254 The nervous and immune systems are classically studied as two separate entities.

255 argeting both voltage-gated Ca(2+) channels, classically studied for neurodegenerative diseases, and

256 motor neuronal modules in the spinal cord is classically studied through electrical stimulation or mu

257 ventricle in addition to the left ventricle classically studied.

258 Dynamic proteins in the nucleus are classically subdiffusive and undergo anomalous diffusion

259 Classically, such models would be considered overfitted,

260 Glucagon levels are classically suppressed after glucose challenge.

261 While comorbidities such as classically syndromic presentation or immune deficiency

262 Classically, TD learning imparts value to features that

263 mes they are predominantly evoked responses [classically termed steady-state responses (SSRs)] that a

264 Classically, the CD56dim NK cell subset is thought to me

265 Classically, the interaction between NP and viral RNA (v

266 Classically, the mechanism responsible for antigen proce

267 Classically, the NLRP3 inflammasome in murine macrophage

268 Classically, these models are defined in terms of a prob

269 Classically, this critical examination can be either int

270 Classically, this process is driven by the Nernst effect

271 Classically, this reaction is performed with an electrop

272 Although classically thought of as a motor circuit, the cerebellu

273 onment (proteases, allergens, and injury) is classically thought of as a principal contributor to bar

274 In bacteria, protein phosphorylation was classically thought to be mediated exclusively by histid

275 Language is classically thought to be supported by perisylvian corti

276 cy of dendritic cell (DC) cancer vaccines is classically thought to depend on their antigen-presentin

277 ndoderm [9-12], while gnathostome gills were classically thought to derive from ectoderm [10, 13].

278 Cytokines are classically thought to stimulate downstream signaling pa

279 as a result of previous antigenic exposures, classically through previous transplantation, pregnancy,

280 scuss in what way results on the hardness of classically tracking time evolution under local Hamilton

281 Classically, two stimuli have been used to trigger a bei

282 ria in HS incite an infectious disease as we classically understand it or whether bacteria might play

283 y actions via the GC receptor (GR), which is classically understood to function as a nuclear transcri

284 with BH3 was examined experimentally, and a classically unexpected trend is that the selectivity inc

285 mpared the four new deviation indices to the classically used escape latency measures in a vascular d

286 the isolated populations showed that several classically used exosome markers, like major histocompat

287 e random-dot motion discrimination paradigm, classically used in primate studies, to larval zebrafish

288 tree physiological and chemical traits with classically used morphological traits to improve predict

289 m mass spectrometry coupling (HPLC-MS/MS) is classically used to characterize post-transcriptional mo

290 However, the conditions classically used to elicit USV vary greatly with the ani

291 mouse strains, that is, BALB/c and C57BL/6, classically used to study mycobacterial infection, and F

292 raphene electronic states in the presence of classically vibrating nuclei.

293 The hippocampal CA3 region is classically viewed as a homogeneous autoassociative netw

294 Although classically viewed as a type 2-regulated disease, type 1

295 Although urate has been classically viewed as an antioxidant with beneficial eff

296 n glucose metabolism, and their secretion is classically viewed as being inversely regulated.

297 Although they are classically viewed as continuously recirculating through

298 The central nervous system (CNS) is classically viewed as immune-privileged; however, recent

299 Classically, visual processing is described as a cascade

300 It is classically well perceived that cathode-air interfacial