ライフサイエンスコーパス: clinical importance

1 agnostic test for canine bartonelloses is of clinical importance.

2 c targets for preventing podocyte injury has clinical importance.

3 creasingly incorporated components of lesser clinical importance.

4 tor network regulation also has considerable clinical importance.

5 he lower risk did not exceed a criterion for clinical importance.

6 y of scientific interest, but also of direct clinical importance.

7 sions and Relevance: Measles remains of high clinical importance.

8 a a simple noninvasive procedure is of great clinical importance.

9 unique properties of these cells that are of clinical importance.

10 the race-centric networks and of particular clinical importance.

11 vention benefits were small and of uncertain clinical importance.

12 p for incidental imaging findings of limited clinical importance.

13 gh statistically significant is of uncertain clinical importance.

14 bolic-related disease, including BrCA, is of clinical importance.

15 red to postpartum is not considered to be of clinical importance.

16 hibition is not fully understood despite its clinical importance.

17 nt stem cells during lung regeneration is of clinical importance.

18 ne on inhibitory control may thus be of high clinical importance.

19 unistic mycobacterial pathogen of increasing clinical importance.

20 tion consequent to neuronal injury may be of clinical importance.

21 ute risk increase was small and of uncertain clinical importance.

22 toward HCV GT-1a, a strain with significant clinical importance.

23 cingulate cortex function is likely to be of clinical importance.

24 d be a useful biomarker for determination of clinical importance.

25 dered a fundamental cerebellar impairment of clinical importance.

26 ith prognosis, suggesting its biological and clinical importance.

27 ifference between treatments is of uncertain clinical importance.

28 l validation, as well as assessment of their clinical importance.

29 r insufficient for many outcomes of greatest clinical importance.

30 of secondary metabolites, some of which have clinical importance.

31 ible S. aureus (MSSA), despite its continued clinical importance.

32 nderstanding their mechanism of action is of clinical importance.

33 s been revealed in adult humans and has high clinical importance.

34 en questions were rated as being of greatest clinical importance.

35 es as well as further investigation of their clinical importance.

36 can reveal tumor subgroups of biological and clinical importance.

37 ocedural myocardial infarctions of uncertain clinical importance.

38 e, but this improvement is unlikely to be of clinical importance.

39 vulnerability to ischemia are of increasing clinical importance.

40 variants), leaving 334 variants of potential clinical importance.

41 f undesirable postoperative outcomes, are of clinical importance.

42 ion of probable autoimmune hepatitis and its clinical importance.

43 specific off-target promiscuity of potential clinical importance.

44 event or delay such occurrences are of great clinical importance.

45 ratumor heterogeneity is therefore of direct clinical importance.

46 anner, MDT revealed information of potential clinical importance.

47 differences versus placebo were of uncertain clinical importance.

48 s statistically significant but of uncertain clinical importance.

49 me (P = 0.02), but this appeared to be of no clinical importance.

50 did not meet the prespecified threshold for clinical importance.

51 t enigmatic malaria proteins with the utmost clinical importance.

52 dida albicans, two pathogenic fungi of major clinical importance.

53 oprotein), plaque erosion may assume greater clinical importance.

54 he effect sizes were modest and of uncertain clinical importance.

55 din in epidermal regeneration with potential clinical importance.

56 for developing Alzheimer disease (AD) is of clinical importance.

57 RGS2, in particular, could have broad clinical importance.

58 increasingly understood to have significant clinical importance.

59 inodal targets is likely to be of increasing clinical importance.

60 symptoms at 4-month follow-up, of uncertain clinical importance.

61 delineates our current understanding of the clinical importance, aetiology and pathophysiology of ac

62 tion in HIV-infected populations are of high clinical importance, although evidence supporting lung c

63 Furthermore, we highlight their clinical importance and analyze the development of drugs

64 s (GABA(A)Rs) are of great physiological and clinical importance and have long been thought to be det

65 Further studies are needed to determine the clinical importance and long-term consequences of these

66 Despite the clinical importance and significant cost of short-term m

67 The experts developed four questions of clinical importance and used an evidence-based strategy

68 response (UPR), a signaling pathway of great clinical importance, and could for the first time detect

69 econdary); ease of use, usefulness, benefit, clinical importance, and feasibility (tertiary).

70 burden for data collection, has substantial clinical importance, and has acceptable reliability.

71 ong pathogenic bacteria is an issue of great clinical importance, and new approaches to therapy are u

72 Many of these findings are of clinical importance, and ongoing studies implementing cl

73 ing the prevalence of pathogenic variants of clinical importance, and show that 2% of this population

74 rebral embolic events have become a focus of clinical importance as complications of vascular procedu

75 of schizophrenia or related disorders are of clinical importance as these are associated with a range

76 I interferonopathies becoming of increasing clinical importance as treatment options are developed b

77 ERalpha status is of clinical importance, as ERalpha-positive breast cancers

78 dynamics in vivo in patients has significant clinical importance, as the structure and function is al

79 These bacterial aggregates are of clinical importance, as they are a major source of recur

80 This integrated concept is of potential clinical importance because it offers numerous innovativ

81 Recognizing patients with CID/HIES is of clinical importance because of the difference in prognos

82 rogression to WHO grade III or IV is of high clinical importance because the initiation of a specific

83 uggests that these four parameters can be of clinical importance because we find them to be significa

84 Our data are of clinical importance, because they indicate that both CD1

85 spectroscopy have recently gained increasing clinical importance, being rapid-, non-invasive and inex

86 g progression to metastasis is of particular clinical importance, but is not easily analyzed by recen

87 elin biology is therefore of fundamental and clinical importance, but no tools currently exist to des

88 Despite the clinical importance, cell-intrinsic molecular mechanisms

89 odel using both statistical significance and clinical importance criteria for variable selection.

90 Despite their clinical importance, current medications do not improve

91 In addition to its clinical importance, DBS presents a powerful approach to

92 the host for months or years and might be of clinical importance during NK cell adoptive immunotherap

93 Despite its basic and clinical importance, early human embryonic development r

94 ossreactive memory T cells are of particular clinical importance, especially given the emergence of c

95 dii is an obligate intracellular parasite of clinical importance, especially in immunocompromised pat

96 x16 is a lung cancer oncogene with potential clinical importance for a proportion of patients.

97 tyrosinase (TY), was selected based on their clinical importance for a range of pathologies.

98 vessel network is a question of significant clinical importance for autoimmunity, tumor immunology,

99 in the testes at the microscale level is of clinical importance for delivering high doses of radiati

100 recise spatiotemporal regulation-is of major clinical importance for development of therapeutic inter

101 nonaggressive prostate cancer is of critical clinical importance for disease prevention and treatment

102 onnect at the cellular level is of paramount clinical importance for optimizing treatment strategies

103 s (k = 59) show a small benefit of uncertain clinical importance for patients and their caregivers.

104 ry ago, the TSE of MRT in the testes and its clinical importance for preventing male fertility remain

105 stem/progenitor cells (HSPCs) ex vivo is of clinical importance for stem cell expansion and gene the

106 residual endogenous glucose production is of clinical importance given the risk of sudden death in th

107 Despite their potential clinical importance, how CSCs are regulated at the molec

108 Despite their potential clinical importance, how CXCR4 expression in breast canc

109 Despite its functional and clinical importance, how vascular cells integrate phosph

110 estimating thresholds could be of particular clinical importance in combination with focused stimulat

111 (KPC) is an emerging problem of significant clinical importance in Gram-negative bacteria.

112 sms of TACC3-mediated EMT and its functional/clinical importance in human cervical cancer remain elus

113 lanoma and discover new genes with potential clinical importance in human melanoma.

114 Despite its clinical importance in infection and autoimmunity, the a

115 ccurately assess acute ischemia, which is of clinical importance in intensive care and in kidney tran

116 central and peripheral nervous system is of clinical importance in neural injury and neurodegenerati

117 f scientific inquiry to address questions of clinical importance in periodontology for which there is

118 Despite their clinical importance in sexually transmitted infection an

119 pertoire of pollen allergens of a grass with clinical importance in subtropical regions, where an inc

120 and that such disturbance is of significant clinical importance in terms of behavioral symptoms.

121 These activities may have clinical importance in terms of new treatments, targeted

122 ered a benign laboratory finding with little clinical importance in the absence of gout or kidney sto

123 pparent DENV and may represent biomarkers of clinical importance in the context of dengue illness.

124 arly diagnosis and risk stratification is of clinical importance in the long QT syndrome (LQTS), howe

125 Liver regeneration is of major clinical importance in the setting of liver injury, rese

126 Detecting these variants has clinical importance in the treatment of diseases.

127 mutations and oncogenic driver alleles with clinical importance in the treatment of human cancer.

128 ing TNBC and discovered genes with potential clinical importance in TNBC.

129 tated or amplified cancer genes of potential clinical importance included PI3K (PIK3CA, AKT1, PIK3CG)

130 immunity in chronic inflammatory diseases of clinical importance, including cancers.

131 One emerging area of clinical importance is differential responsiveness to CB

132 ciations were statistically significant, the clinical importance is relatively modest.

133 Despite its clinical importance, it is largely unknown how cytokine

134 Of particular clinical importance, lenalidomide also allowed NK cells

135 Despite its clinical importance, little is known about innate immuni

136 Despite its clinical importance, little is known about its emergence

137 Despite the clinical importance, little is known about the gene regu

138 Despite their clinical importance, little is known about the host fact

139 Despite its clinical importance, little is known about the human imm

140 Despite its clinical importance, little is known about the molecular

141 However, despite its clinical importance, little is known about the principle

142 is, PET using labeled amino acids has gained clinical importance, mainly regarding the differentiatio

143 Despite the clinical importance, no DENV vaccine or anti-DENV drug i

144 Despite its clinical importance, no vaccine prophylaxis against RSV

145 Such a capability could be of great clinical importance, not only in patients with hypoxic o

146 This study demonstrates the clinical importance of a discharge diagnosis of critical

147 These data highlight the clinical importance of a thorough understanding of Notch

148 We investigated the frequency and clinical importance of acquired asymptomatic brain magne

149 The clinical importance of albuminuria as a predictor of kid

150 arallel with this growing recognition of the clinical importance of apathy, significant advances have

151 Despite the functional and clinical importance of arteriogenesis, the biology of th

152 am:inhibitor combinations and the continuing clinical importance of beta-lactams mean that this remai

153 To investigate the clinical importance of changes in diabetic retinopathy s

154 ic value in heart failure (HF), although the clinical importance of changes in NP from baseline is un

155 article is to summarise imaging findings and clinical importance of congenital anomalies of seminal v

156 The clinical importance of CRT expression was revealed in th

157 Although the clinical importance of CSCs remains unproven, new eviden

158 here has been great progress in defining the clinical importance of CTCs, and it now seems likely tha

159 Given the clinical importance of D2 antagonists, the goal of this

160 These effect sizes emphasise the clinical importance of direct interventions.

161 Despite the clinical importance of disproportionate memory for negat

162 The clinical importance of drug-nutrient interactions was hi

163 These data highlight the clinical importance of evaluating adults with histiocyto

164 The efficacy, safety, and clinical importance of extended-duration thromboprophyla

165 All previous studies assessing the clinical importance of extent of resection have not acco

166 Considering the potential clinical importance of focal lamina cribrosa (LC) defect

167 Despite the clinical importance of herpes simplex virus (HSV)-induce

168 Despite the clinical importance of HSV-2, relatively little is known

169 Recently the clinical importance of human organic cation transporters

170 Despite the clinical importance of hypoxia, modulation of hypoxic in

171 subset of prostate tumors and highlight the clinical importance of identifying molecularly defined t

172 Despite the clinical importance of identifying the HLA types, very f

173 The physiological and clinical importance of IGF-1 prompted challenging chemic

174 over time and examine temporal trends in the clinical importance of individual components of these co

175 However, the clinical importance of individual splice variants and th

176 s Review, we discuss the epidemiological and clinical importance of influenza and respiratory bacteri

177 Despite the prevalence and clinical importance of influenza, its long-term effect o

178 These results illustrate the clinical importance of ligand-induced resistance to kina

179 ore heterogeneous, potentially revealing the clinical importance of local features and intertumoral h

180 The possible clinical importance of many of the various IGH transloca

181 To investigate the clinical importance of MCT4 in GBM, we examined clinical

182 Despite the clinical importance of metastasis, there remain fundamen

183 The clinical importance of microbial causes of dacryocystiti

184 The relative prevalence and clinical importance of monogenic mutations related to fa

185 Because of the clinical importance of MTA1 established in PD, we looked

186 isease modalities has recently increased the clinical importance of NIS.

187 These findings suggest clinical importance of nonobstructive CAD and warrant fu

188 The clinical importance of our findings were further investi

189 The clinical importance of pAKT localization and the mechani

190 However, the clinical importance of Paneth cells' associations with s

191 The clinical importance of peanut (Arachis hypogaea) allergi

192 The clinical importance of PIP5K1alpha and its association w

193 The clinical importance of podocyte binding to the GBM via a

194 Despite the clinical importance of polymyxins and the emergence of m

195 These findings demonstrate the clinical importance of primary infection with this rapid

196 Low treatment rates highlight the clinical importance of questioning patients about eating

197 The clinical importance of reducing 2-hour glucose level in

198 Given the clinical importance of rhinovirus, we sought to determin

199 Despite the clinical importance of S. saprophyticus, little is known

200 Considering the biological and clinical importance of S6K1, a complete understanding of

201 cent literature describing the detection and clinical importance of serum antibodies in patients with

202 mphocytic leukemia (CLL) and demonstrate the clinical importance of small TP53-deleted subclones dete

203 The clinical importance of SREBP-2 is revealed in patients w

204 n this article, we review the mechanisms and clinical importance of statin toxicity and focus on the

205 and regulatory agencies in interpreting the clinical importance of statistically significant finding

206 These findings indicate the clinical importance of studies into the molecular hetero

207 The clinical importance of subclinical, early T cell-mediate

208 ases versus controls, and the prevalence and clinical importance of such mutations in an asymptomatic

209 Purpose To evaluate the effect and clinical importance of sunitinib on pancreatic volume in

210 Despite the clinical importance of T(reg) cells, there is a dearth o

211 sly controlled active infections support the clinical importance of T-cell immunity in mediating prot

212 Given the biological and clinical importance of the ALK1 signaling pathway, we so

213 These findings corroborate the clinical importance of the C9ORF72 mutation in frontotem

214 issue of Blood, Steinberg et al describe the clinical importance of the distribution or "packaging" o

215 Further research is needed to assess the clinical importance of the effect size and to determine

216 The heterogeneity and the increasing clinical importance of the Enterobacter cloacae complex

217 Further research is needed to understand the clinical importance of the findings.

218 Despite the clinical importance of the itch sensation, its mechanism

219 However, the clinical importance of the microbiome in tuberculosis, t

220 further research is needed to understand the clinical importance of the observed differences.

221 Despite the clinical importance of the ocular motor system, little i

222 Depending on the clinical importance of the respective errors, careful co

223 e should be considered when interpreting the clinical importance of the study.

224 Although the clinical importance of these "rising" clones remains to

225 The clinical importance of these chemokines was validated by

226 However in this preliminary work the clinical importance of these degrees of misalignment was

227 Further research is needed to assess the clinical importance of these differences and measure lon

228 The clinical importance of these differences is uncertain an

229 Further research is needed to determine the clinical importance of these efficacy and adverse event

230 The potential clinical importance of these endothelial lncRNAs to vasc

231 However, despite the clinical importance of these findings and the potential

232 The clinical importance of these findings in asthmatic patie

233 not given; the challenges of researching the clinical importance of these findings or seeking special

234 The clinical importance of these findings remains to be dete

235 The clinical importance of these findings will require furth

236 The clinical importance of these findings, and whether they

237 rosclerotic lesions underlying the potential clinical importance of these findings.

238 ma lung epithelium, underlying the potential clinical importance of these findings.

239 ma lung epithelium, underlying the potential clinical importance of these findings.-Shi, N., Zhang, J

240 The clinical importance of these integrins has also become c

241 V-1C virus with PYxE insertion indicates the clinical importance of these viral variants.IMPORTANCE G

242 However, the clinical importance of this association is uncertain.

243 The clinical importance of this difference is uncertain.

244 further research is needed to determine the clinical importance of this difference.

245 Further research is needed to understand the clinical importance of this finding in patients with hyp

246 n should be considered when interpreting the clinical importance of this finding.

247 The clinical importance of this improvement remains to be de

248 KV during pregnancy(15-20), highlighting the clinical importance of this infection.

249 With regard to the potential clinical importance of this pathway, NRG4 expression was

250 n urinary CCL7 levels in AKI, supporting the clinical importance of this pathway.

251 The clinical importance of this stress response remains to b

252 erative disorders in humans, emphasizing the clinical importance of this system.

253 Therefore, we sought to study the clinical importance of TLRs in HCV genotype 1 patients w

254 Despite the clinical importance of venous thrombus resolution, the c

255 are prevalent in asthmatic patients, but the clinical importance of ventilation defects is poorly und

256 The clinical importance of vitamin A as an essential nutrien

257 which are relatively well understood and the clinical importance of which has long been recognized.

258 nerate human neurons of specific subtypes of clinical importance offers experimental platforms that m

259 oject were to identify MATE1 inhibitors with clinical importance or in vitro utility and to elucidate

260 Although clinical importance remains to be substantiated, results

261 n of disease progression, which, despite its clinical importance, remains poorly understood with resp

262 s of genomic variation that are currently of clinical importance, review approaches to interpreting g

263 Of clinical importance, Sema3E and Plexin D1 were found to

264 roporation-based technologies that may reach clinical importance, such as gene electrotransfer, elect

265 These alterations could have significant clinical importance, such as the case of Pseudomonas aer

266 Many bacteria of clinical importance survive and may grow in different en

267 Despite potential clinical importance, target cells for mother-to-child tr

268 Despite its clinical importance the global effects of vancomycin exp

269 In addition, and of clinical importance, the cohort of p53-null clones showe

270 Despite its clinical importance, the exact mechanism by which daptom

271 Despite its physiological and clinical importance, the interaction of IgG and FcRn rem

272 Despite its clinical importance, the mechanisms that mediate or gene

273 Despite its physiological role and clinical importance, the molecular basis of its action i

274 Despite this clinical importance, the molecular basis of the brain me

275 Despite its clinical importance, the molecular biology of HIV-1 late

276 Despite their clinical importance, the molecular mechanisms by which v

277 Despite their fundamental biological and clinical importance, the molecular mechanisms that regul

278 Despite its clinical importance, the molecular mechanisms underlying

279 Despite its clinical importance, the molecular regulation of neutrop

280 Despite its clinical importance, the normal role of UBE3A in neurons

281 Despite its clinical importance, the pathogenic mechanism linking th

282 Despite its clinical importance, the underlying neural mechanisms of

283 3,14), but despite its substantial basic and clinical importance, the underlying neurophysiology of t

284 Due to their clinical importance, there is a pressing need for effect

285 However, despite its clinical importance, there remains limited understanding

286 statistically significant, but of uncertain clinical importance; there was no significant difference

287 Despite its basic and clinical importance, this process remains mysterious in

288 ombi after myocardial infarction would be of clinical importance to estimate the risk for embolizatio

289 s edema resolution, which is of biologic and clinical importance to patients with IAV-induced lung in

290 o provide timely guidance on a topic of high clinical importance to the AGA membership, and underwent

291 rovide timely perspective on a topic of high clinical importance to the AGA membership, and underwent

292 o provide timely guidance on a topic of high clinical importance to the AGA membership.

293 Of clinical importance, we observed that elevated MT1-MMP e

294 Few differences of clinical importance were found for core illness symptoms

295 Factors with a P value of less than 0.1 and clinical importance were included in the multivariable l

296 y significant group differences of uncertain clinical importance were observed for several comparison

297 We conclude that secondary variants of high clinical importance will be detected at an appreciable f

298 y-resistant LSCs, a cellular entity of prime clinical importance, will be required to develop additio

299 e tolerance that was modest and of uncertain clinical importance, with a higher likelihood of major c

300 This might be of clinical importance within the context of neuronal disea