ライフサイエンスコーパス: clonal growth

1 on the tumor cells and promotes invasion and clonal growth.

2 ic diversity to alleviate problems caused by clonal growth.

3 ring gain-of-function RTK activity promoting clonal growth.

4 ion in ovarian cancer cell proliferation and clonal growth.

5 -7 and T47D cells dramatically reduced their clonal growth.

6 shly isolated bovine stromal cells exhibited clonal growth.

7 significantly increased viability (>40%) and clonal growth (10-fold increase in colonies) after serum

8 The factors controlling the clonal growth ability of individual cancer cells remain

9 poietin (Epo)) did not significantly enhance clonal growth above that observed in response to KL+FL+T

10 rt the conclusion that breakdown of coherent clonal growth accompanies epithelialization of the epibl

11 ies, loss-of-function DDR alterations confer clonal growth advantage and adverse prognostic impact bu

12 A mechanism for clonal growth advantage in isolated del(5q) disease rema

13 ce screens and identified genes conferring a clonal growth advantage on normal and neoplastic (cutane

14 lected for in oncogenesis because it confers clonal growth advantage, may also provide an important m

15 nt with blocking antibodies to fas augmented clonal growth and abrogated the clonal inhibitory effect

16 use many epiphytic vascular plants undertake clonal growth and because vascular epiphytes colonize ca

17 ould act as a switch, regulating appropriate clonal growth and decline while, in parallel, shaping a

18 an in vitro stroma-dependent system for the clonal growth and differentiation of natural killer (NK)

19 IL-7 alone did not induce any clonal growth and FL alone gave rise to a few clusters (

20 on variability but did slightly reduce their clonal growth and increase their bud dormancy.

21 ts of cav-1 on prostate cancer cell survival/clonal growth and metastatic activities.

22 dently promote prostate cancer cell survival/clonal growth and metastatic activities.

23 ufficiency leads to an increased ability for clonal growth and proliferation in the PMECs of BRCA1 mu

24 of T-mediated prostate cancer cell survival/clonal growth and that modest levels of cav-1 can indepe

25 cell (CSC) characteristics such as enhanced clonal growth and tumor regenerative capacity.

26 Extensive clonal growth and vegetative dispersal can disrupt the f

27 rface-associated cells form microcolonies by clonal growth and/or aggregation, (iii) microcolonies tr

28 nt and mortality in juveniles, activation of clonal growth, and absence of plant size-dependent morta

29 in MDA-MB-231 cells resulted in a decreased clonal growth, and stable up-regulation significantly de

30 where somatic gene alterations and enhanced clonal growth are selected for by carcinogens, and exami

31 dependent hPS cells to xeno-free conditions, clonal growth as well as single-cell survival in the abs

32 (as regards ploidy), likely with predominant clonal growth, as is common in conjugate algae, resultin

33 ndependence from exogenous growth factors in clonal growth assays and induction of DNA synthesis afte

34 single-cell molecular analytical methods and clonal growth assays are enabling more refined models of

35 Using clonal growth assays of cultured keratinocytes as a quan

36 However, in vitro clonal growth assays performed on peripheral blood from

37 .5-diphenyl-2H-tetrazolium bromide (MTT) and clonal growth assays.

38 s variations, biomineralization, colonial or clonal growth, bioerosion, deposit feeding, bioturbation

39 Tpo alone stimulated limited clonal growth, but synergized with c-kit ligand (KL), fl

40 receptor on HUC surfaces, stimulation of HUC clonal growth by HB-EGF, inhibition of HB-EGF-stimulated

41 growth/differentiation potential, including clonal growth capability, reversible commitment to diffe

42 combinations (EGF, NGF) yielded the highest clonal growth capacity and an undifferentiated cellular

43 nally, we show that mutations driving faster clonal growth carry a higher risk of malignant progressi

44 escent time-lapse imaging was used to assess clonal growth, cell motility, and cell-cycle progression

45 m and transit-amplifying cells, as judged by clonal growth characteristics.

46 rriers (n = 9) had a 28% greater ability for clonal growth compared with normal controls (n = 6; P =

47 quent risk of cancer development or aberrant clonal growths due to vector insertion near or within pr

48 correct Pax6 dosage is necessary for normal clonal growth during corneal development, normal limbal

49 otent than 1,25(OH)(2)D(3) in inhibiting 50% clonal growth (ED(50)) of NB4, HL-60, MCF-7, and LNCaP c

50 Clonal growth generally decreased as the power density a

51 uccessful in most years due to its resilient clonal growth in a changing climate.

52 required for metastatic ability in vivo and clonal growth in cell culture.

53 A study on clonal growth in Chinese hamster ovary (CHO) cells was c

54 Clonal growth in culture is assessed after 14 d, while e

55 biology 402 (MCDB 402)] optimized for their clonal growth in minimal serum, they produced transforme

56 etroviral infection markedly inhibited their clonal growth in monolayer and soft agar cultures, and i

57 onal studies indicate that Bimgamma inhibits clonal growth in prostate cancer cells and promotes apop

58 d burn sepsis-induced bone marrow progenitor clonal growth in response to macrophage- and granulocyte

59 dequate to achieve a 50% inhibition of MCF-7 clonal growth in soft agar in the absence of the analog,

60 dequate to achieve a 50% inhibition of MCF-7 clonal growth in soft agar in the absence of the analogu

61 o, colchicine was associated with attenuated clonal growth in TET2 CH (beta(time) on colchicine: 0.09

62 dequate to achieve a 40% inhibition of MCF-7 clonal growth in the absence of the analogue, suggesting

63 Osteopontin-CD44s-TIAM1 promotes clonal growth in vitro but not at high cell density.

64 cells in NK cell development, in supporting clonal growth, in initiation of Ly49 receptor expression

65 A irreversibly and synergistically inhibited clonal growth, induced differentiation and apoptosis of

66 Clonal growth is a major factor governing maximum lifesp

67 Some localized clonal growth is apparent.

68 Clonal growth leads to an expansion in the size of genet

69 Selection for clonal growth may occur in tumor cells that have modest

70 tion, decreases lactate production, inhibits clonal growth, migration and invasion of ovarian cancer

71 ned stimulation with FL and IL-7 resulted in clonal growth of 10% of Lin-Sca-1+ bone marrow cells.

72 Our in vitro culture system for the clonal growth of a single colonic crypt cell suspension

73 Addition of IL-6 antibody did not inhibit clonal growth of any of the cell lines.

74 ansfection shows cyclin E enhances the basal clonal growth of BEAS-2B cells.

75 e activities than 1,25(OH)2D3 when measuring clonal growth of breast (MCF-7) and prostate (LNCaP) can

76 sional hydrogel culture system that supports clonal growth of CD133+Sox2+, CD133+Sox2-, and CD133-Sox

77 ndromas in our mouse model do not arise from clonal growth of chondrocytes, they cannot be considered

78 As the culture system supports clonal growth of DP cells and maintenance of distinct DP

79 enomes) of different species and not through clonal growth of genetically identical cells.

80 epatocytes required epidermal growth factor, clonal growth of hepatoblasts was potentiated without ep

81 oligonucleotides to C/EBP epsilon, decreased clonal growth of HL-60 and NB4 cells by about 50% compar

82 For inhibition of cellular clonal growth of human leukemia (HL-60) and breast cance

83 The epidermis was observed to form from clonal growth of individual keratinocytes into epithelia

84 titative model revealing basic principles of clonal growth of individual neoblasts.

85 yp markedly suppressed anchorage-independent clonal growth of KCL22 cells.

86 g antisense oligonucleotides showed that the clonal growth of KS-1 and BC-1 was nearly 100% inhibited

87 nded to prevent differentiation and maintain clonal growth of limbal epithelial progenitors.

88 CaP cells stimulated increased viability and clonal growth of low passage, caveolin-1-negative, andro

89 tent vitamin D3 analogue markedly inhibiting clonal growth of MCF-7 and SK-BR-3 cells with concomitan

90 TGZ (10(-5) M, 4 days) reversibly inhibits clonal growth of MCF7 breast cancer cells and the combin

91 is model should be valuable for studying the clonal growth of melanocytes in the context of the epide

92 he colony size distribution assay for 10-day clonal growth of mouse LE cells.

93 r-beta 1 (TGF-beta l) potently inhibited the clonal growth of murine Lin-Sca-l+ bone marrow progenito

94 n D3 analogs alone were potent inhibitors of clonal growth of NB4 cells, an APL cell line (ED50, appr

95 reas KL and FL in combination stimulated the clonal growth of only 3% of CD34+ CD38- cells, 40% of CD

96 Finally, we demonstrate that NT stimulated clonal growth of PANC-1 cells in semisolid medium, which

97 sure to the agent irreversibly inhibited 50% clonal growth of PC-3 cells.

98 oma (MM) is characterized by an uninhibited, clonal growth of plasma cells.

99 Surprisingly, Ro 25-9716 also inhibited the clonal growth of poorly differentiated leukemia cell lin

100 mulation approaches were used to analyze the clonal growth of preneoplastic, enzyme-altered foci duri

101 n of revertant fibers is demonstrated by the clonal growth of revertant clusters with age, suggesting

102 ated PPARgamma regulated differentiation and clonal growth of several types of cancer cells, includin

103 elanocytes were in clusters, consistent with clonal growth of the cells.

104 pha (IFN-alpha) and IFN-gamma suppressed the clonal growth of the PEL cells, but GM-CSF, IL-4, IL-6,

105 C/EBP-epsilon caused a fivefold decrease in clonal growth of these cells.

106 ed, but not submerged, explants showed vivid clonal growth on 3T3 fibroblast feeder layers and comple

107 ns, with genetic identity coming from recent clonal growth or horizontal gene transfer (HGT).

108 thogens, particularly during long periods of clonal growth or while expanding into new environments.

109 predictive of new CHIP clone acquisition and clonal growth over extended follow-up, providing valuabl

110 y tumour progression and offer insights into clonal growth patterns during tumour development.

111 These provide the basis for studying clonal growth patterns, and the histological characteris

112 sease-causing somatic mutations can initiate clonal growth prior to the appearance of any disease sym

113 Faster clonal growth rate was associated with increased risk of

114 We present here a biologically based clonal growth simulation platform to describe the growth

115 After population expansion and clonal growth, the proliferating hepatocytes can return

116 potential of stochastic fluctuations during clonal growth to rapidly generate phenotypically indepen

117 und organs in individual species and whether clonal growth traits, phenology or environmental conditi

118 These transformants exhibited clonal growth under serum-deprived conditions.

119 o proliferate in culture, can now enter into clonal growth under the influence of hepatocyte growth f

120 he commonest type of asexual reproduction is clonal growth (vegetative propagation) in which parental

121 ofluorescence staining, and Western blot; SC clonal growth was measured on 3T3 feeder layers.

122 A wavelength dependence of clonal growth was observed, with maximum clonability at

123 e genotype of drug-selected resistant cells, clonal growth was restored.

124 ster ovary cells restored a reduced level of clonal growth, whereas a T339I mutant supported growth a

125 wo phenotypic states can be inherited during clonal growth, yet are reversible.