ライフサイエンスコーパス: co-opt

1 y proteins, E1B55K and E4orf6, that together co-opt a cellular ubiquitin ligase complex to overcome h

2 ur studies suggest that squirrels and camels co-opt a common molecular strategy to adapt to hot envir

3 RNA viruses co-opt a large number of cellular proteins that affect v

4 Here we show that B2BM cells co-opt a neuronal signalling pathway that was recently i

5 ding capacity and are therefore obligated to co-opt a significant amount of cellular factors to trans

6 in Drosophila, the nuclear piRNA pathway has co-opted a conserved mechanism of SUMO-dependent recruit

7 We propose that Caulobacter has co-opted a nucleoid-associated protein with high AT reco

8 Primates have co-opted a viral gene to produce an envelope protein tha

9 These viruses make sfRNAs by co-opting a cellular exonuclease via structured RNAs cal

10 The evolution of a receptor co-opting a conserved pathogen target contrasts with oth

11 the two tissues to promote tumorigenesis, by co-opting a normal regulatory mechanism that prevents th

12 57, suggesting that this syndrome evolved by co-opting a preexisting age-dependent program.

13 the mechanisms through which the tumour cell co-opts a normal fibroblast.

14 Thus, we propose that assembling HIV-1 co-opts a preexisting host complex containing cellular f

15 study reveals how the human spliceosome has co-opted additional proteins to modulate a conserved RNA

16 We have shown that C. albicans co-opts amino acid catabolism to generate and excrete am

17 ose species that have a fully folded H2 have co-opted an alternative mechanism for promoting p150(Glu

18 Our data indicate that neurons have co-opted an ancient RNA modification mechanism to regula

19 izes its niche through oncogenic mutation by co-opting an underlying homeostatic process.

20 These results suggest Mtb co-opts an evolutionary recent IFN-IL6-CEBP feed-forward

21 In this way, the parasite co-opts an immune response in a way that enhances its ow

22 Thus, HSV-1 co-opts an innate immune pathway resulting from IL-1 sti

23 Bacteria masterfully co-opt and subvert host signal transduction.

24 aling and receptor trafficking, which can be co-opted and amplified in mutant p53-driven cancer cells

25 g this new nutrient niche contingent on both co-opting and overcoming a history of prior adaptation.

26 sexual deception, pollination is achieved by co-opting and regulating two independent biosynthetic pa

27 ow report that the Cd8 coreceptor gene locus co-opts any coreceptor protein encoded within it to indu

28 The distributions of sequences that can be co-opted are biased with respect to codons, and phasing

29 opod shell has another function and has been co-opted as a defense system to encase and kill parasiti

30 ght emission served another function and was co-opted as an aposematic signal later in the diversific

31 riants, which might have been evolutionarily co-opted as an essential part of the adaptive genetic re

32 only example of an exoskeleton that has been co-opted as an immune system.

33 n these transcription units, which have been co-opted as gene regulatory mechanisms.

34 rect natural selection are more likely to be co-opted as mating cues, leading to the appearance of ma

35 t of lateral openings that subsequently were co-opted as pharyngeal gills.

36 We show that budding yeast Ty3/Gypsy co-opts binding sites of the essential meiotic transcrip

37 how host specialization can enable aphids to co-opt both the phytohormonal responses and defensive co

38 nd environmental inputs are consolidated and co-opted by a latent virus to balance lifelong infection

39 al strategy of the virus may be successfully co-opted by autonomous host cells and play a role in les

40 cell puncturing nanomachines that have been co-opted by bacteria for self-defense against both bacte

41 roblast growth factor (FGF) signaling may be co-opted by breast cancer cells.

42 The vesicular trafficking pathways co-opted by C. burnetii for PV development are poorly de

43 pithelial-to-mesenchymal transition (EMT) is co-opted by cancer cells to metastasize to distant sites

44 lly involved in immune cell homeostasis, are co-opted by cancer cells to thwart the development of ef

45 in maintaining self-tolerance, which can be co-opted by cancer to evade immune attack.

46 ring anti-microbial immune responses, can be co-opted by cancer to evade immune destruction.

47 tain mechanisms enabling regeneration may be co-opted by cancer to promote growth at primary and meta

48 protein that acts as a "don't eat me" signal co-opted by cancers to evade innate immune surveillance,

49 Cas1-2, whereas the prespacer processing is co-opted by cellular non-Cas exonucleases, thereby offse

50 view that the karilysin catalytic domain was co-opted by competent bacteria through horizontal gene t

51 rmicutes and demonstrate that they have been co-opted by hosts as "anti-anti-CRISPRs," repressing pha

52 allergic inflammatory circuitry that can be co-opted by metastatic cancer cells to facilitate lung c

53 neutrophils and neutrophil-derived IL-10 are co-opted by nematode parasites and other pathogens to at

54 Furthermore, this allosteric mechanism is co-opted by pathway branchpoint enzyme chorismate mutase

55 Cu-microRNA regulatory circuits are further co-opted by plants to regulate both beneficial and patho

56 sential mediator of the ALT mechanism and is co-opted by post-translational mechanisms to maintain te

57 t a single molecular mechanism may have been co-opted by synaptic partners to ensure joint laminar re

58 ystem for lysosome homeostasis that has been co-opted by the autonomous defense program to clear reca

59 ugh most are silenced, certain TEs have been co-opted by the host.

60 Therefore, OPCs may be co-opted by the immune system in MS to perpetuate the au

61 ossibility is that this feedback response is co-opted by the learning system and used as a template t

62 Endogenous viruses are occasionally co-opted by their hosts to combat other viruses.

63 us, supplemental mechanism of immune evasion co-opted by tumors to evade antitumor immunity and offer

64 action through Irs2 induction, which can be co-opted by Vegf inhibitors to modulate glucose metaboli

65 How EVs co-opt cellular functions to promote replication and spr

66 n and have therefore developed strategies to co-opt cellular processes to optimize infection and coun

67 In this study, we dissected the functions of co-opted cellular ESCRT-I (endosomal sorting complexes r

68 RNA, demonstrating the requirement for these co-opted cellular factors in tombusvirus replicase forma

69 By using TBSV RdRp, we show that the co-opted cellular Hsp70 chaperone and neutral phospholip

70 Taken together, the results show that the co-opted cellular Rpn11 is a critical host factor for to

71 revealed intriguing and complex functions of co-opted cellular translation factors, heat shock protei

72 Co-opting cellular factors for viral translation and vir

73 Tomato bushy stunt virus (TBSV) co-opts cellular ESCRT (endosomal sorting complexes requ

74 hitecture provides an efficient mechanism to co-opt conserved signaling networks for diverse purposes

75 the intracellular parasite Toxoplasma gondii co-opts critical functions of its host cell to avoid imm

76 to rationally design degrader molecules that co-opt CRL4s, much about the organization and regulation

77 Co-opting Cullin4 RING ubiquitin ligases (CRL4s) to indu

78 However, a subgroup of genes was likely co-opted de novo early in the Pooideae.

79 Solid tumors co-opt developmental cues to promote formation of tumor

80 Resistant cells also co-opt developmental pathways and display stem-like prop

81 y of evidence suggests that cancer mimics or co-opts developmental processes to facilitate tumor init

82 cestor of jawless and jawed vertebrates that co-opted different antigen receptor supertypes.

83 iation of the somatic nucleus, and they have co-opted different DNA recombination mechanisms-some pre

84 which striatal cholinergic interneurons can co-opt dopamine terminals to drive GABA release and rapi

85 Inhibition of host factors co-opted during active infection is a strategy hosts use

86 and reactive oxygen species (ROS) have been co-opted during evolution into the regulation of plant g

87 The cellular host factors and pathways co-opted during SARS-CoV-2 and related coronavirus life

88 ate trunk myogenic patterning and how it was co-opted during tail evolution to generate similar muscl

89 Striga, suggesting a pathway that was partly co-opted during the evolution of the haustorium.

90 that may later contribute to adaptation when co-opted--e.g., following a mutation increasing expressi

91 We conclude that (1) ABA was co-opted early in plant evolution to regulate functional

92 plant ARABIDILLO germination functions were co-opted early into both gametophyte and sporophyte, wit

93 olving hermaphrodites became self-fertile by co-opting either of the two redundant male programs.

94 activation of signaling pathways that, when co-opted, enable cancer cells to survive drug treatments

95 eurons expressing a photoactivatable Rac1 to co-opt endogenous growth cone guidance machinery to prec

96 The MR1 antigen-presentation pathway thus co-opts ER chaperones to fulfill its unique ability to p

97 We co-opted Escherichia coli for biomolecular synthesis and

98 underscores why eukaryotic viruses typically co-opt eukaryotic genes and bacteriophages commonly harb

99 use the perivascular space for invasion and co-opt existing vessels as satellite tumour form.

100 ER stress accomplish IRF3 phosphorylation by co-opting existing innate immune pathogen response pathw

101 In addition, viruses co-opt exosome biogenesis pathways both for assembling i

102 ability to break down the shield that tumors co-opt for their defense.

103 pe genes of retroviral origin that have been co-opted for a role in placentation and likely contribut

104 e evolved as chromosomal scaffolds that were co-opted for a similar purpose in striated muscles.

105 volution of swordtails a brain gene has been co-opted for an additional novel function in establishin

106 uctures in vertebrate evolution, having been co-opted for an enormous array of functions.

107 the reproductive regulatory network has been co-opted for behavioral division of labor.

108 unterilluminating photophores were partially co-opted for bioluminescent signalling, leading to compl

109 propose that larger BS in C3 lineages may be co-opted for C3 -C4 and C4 biochemistry requirements.

110 icellular ancestor when an ancestral gene is co-opted for cell adhesion.

111 n event in which a toxic phage gene has been co-opted for core cellular function at the root of a lar

112 iple eukaryotic ribosomal proteins (RPs) are co-opted for extraribosomal "moonlighting" activities, b

113 This stress adaptation mechanism is thus co-opted for growth by cancers, and its inhibition may r

114 del that nuclear import mechanisms have been co-opted for independent roles in ciliary import.

115 base regulation, and that the gill was later co-opted for its central role in gas exchange in more de

116 Here we describe how ingested nicotine is co-opted for larval defense by a unique mechanism.

117 hy response to ultrasonic bat calls has been co-opted for mate location.

118 CRISPR-Cas system in Escherichia coli can be co-opted for programmable transcriptional repression.

119 t evolved in a non-sexual context, and later co-opted for sexual signalling when sound producing orga

120 the idea that these elements are pervasively co-opted for the regulation of host genes.

121 yotes whose RNA-directed nucleases have been co-opted for various technologies.

122 brafish kank genes suggested KANK genes were co-opted for vertebrate vascular development.

123 daptation of the CRISPR/Cas editing platform co-opted from bacteria has provided a mechanism for a me

124 genes for insect pathogenesis may have been co-opted from genes involved in endophytic colonization.

125 clude that multicellular cAMP signalling was co-opted from PKA regulation of protist encystation with

126 The other splice site is co-opted from the gene sequence that is duplicated upon

127 ISPR-associated Rossman fold (CARF) subunits co-opted from type III CRISPR immunity.

128 essure was human imposed and involved humans co-opting functions of defense and reproductive security

129 hen occupying the brain microenvironment and co-opt GABA as an oncometabolite.

130 known, however, about how, or even whether, co-opted genes function in eyespot development.

131 proteins derived from Camelid antibodies, we co-opted GFP as a scaffold for inducing formation of bio

132 show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolis

133 tion and demonstrate that an oncoprotein can co-opt HA biosynthesis to drive malignancy.

134 he results establish RSV's unique ability to co-opt host cell mitochondria to facilitate viral infect

135 Venoms frequently co-opt host immune responses, so study of their mode of

136 s numerous strategies to combat, subvert, or co-opt host immunity.

137 ellular heat shock protein 70 (Hsp70) as the co-opted host factor required for the activation of an N

138 The emerging picture is that many of the co-opted host factors are from highly expressed and cons

139 in yeast also leads to reduction of several co-opted host factors in the viral replicase complex (VR

140 ication of (+)RNA viruses depends on several co-opted host proteins but is also under the control of

141 Although the important roles of co-opted host proteins in RNA virus replication have bee

142 lication complexes by sequestering viral and co-opted host proteins to reach high local concentration

143 h the help of viral replication proteins and co-opted host proteins within large viral replication co

144 p), the viral p33 RNA chaperone, and several co-opted host proteins.

145 al GEF within the multifunctional OtDUB that co-opts host Rac1 signaling to induce changes in cytoske

146 Therefore, we have co-opted IL-8 release from tumors to enhance intratumora

147 e regulatory functions of UTRs, how they are co-opted in cancer, new technologies to interrogate canc

148 architecture of inactive kinase domains was co-opted in the activated dimer but the network hub shif

149 We suggest this system is co-opted in the brain to counteract and regulate aberran

150 hypothesise that WIP genes were subsequently co-opted in the control of morphogenesis of novel multic

151 egulator of Caulobacter crescentus, SpmX, is co-opted in the genus Asticcacaulis to specify stalk syn

152 how retroviruses coevolved with the host to co-opt innate immune sensing pathways designed to fight

153 Thus, cancer cells co-opt innate RNA sensing to induce a chemotactic signal

154 These results suggest that Ubx has been co-opted into a novel eyespot gene regulatory network, a

155 This process has been co-opted into a range of developmental events, and it al

156 activities of two powerful toxins have been co-opted into a single, unique toxin that can induce man

157 Wild-type cells are co-opted into new hair growths by beta-catenin mutant ce

158 to be ancient bacteriophages that have been co-opted into serving their host and can now transfer an

159 rp target in stem chordates and subsequently co-opted into the development of many novel traits in ve

160 e formation and that NOG2-related genes were co-opted into the lignin biosynthesis pathway after the

161 One route by which Toxoplasma co-opts its host cell is through hijacking host organell

162 ncer chromatin states, representing putative co-opted LAVA enhancers.

163 ugh its association with MAL and Rab11b, Nef co-opts Lck switchlike function driving the formation Ca

164 Tumors routinely attract and co-opt macrophages to promote their growth, angiogenesis

165 gen and to present CMV antigen to TH1 cells, co-opting MC secretory granules for antigen processing a

166 ect season, and concurrent temporally driven co-opted mechanisms that sense spatial signals, i.e. nit

167 gate the complexities of the mammalian cell, co-opting mechanisms of cellular physiology while defeat

168 In conclusion, the stress hormone CRH co-opts mechanisms that contribute to the plasticity and

169 ns encode ethologically relevant stimuli and co-opt midbrain reward circuits to promote prosocial beh

170 emia (CML) by showing that these 2 leukemias co-opt miR-486 functions in normal erythroid progenitor

171 V-2 viral genome packing and in host-protein co-opting necessary for viral replication and infectivit

172 Our results reveal that tissues co-opt neutrophils en route for elimination to induce pr

173 l dimension, wherein cancer cells themselves co-opt NKG2D for their own benefit to complement the pre

174 Similar to how a growing tumour can co-opt normal soluble signalling pathways, our findings

175 in which bacterial Tn7-like transposons have co-opted nuclease-deficient CRISPR-Cas systems to cataly

176 tein complexes and provide an example of the co-opting of cellular processes by CMV.

177 s, (b) regulation of PKR activation, and (c) co-opting of RNA granule factors for new roles in viral

178 generate phenotypic novelty: exaptation and co-opting of the ancestral bauplan, the quasi-independen

179 extracellular helminths, in part through the co-opting of tissue repair and remodeling mechanisms, th

180 anti-tumoral immunity and escape, revealing co-opting of tissue-specific immune development in the t

181 We propose that the 'co-opting' of sour and bitter neural pathways evolved as

182 olved exquisite virus-host interactions that co-opt or evade a number of host pathways to enable the

183 hat suggest that TE proteins have often been co-opted or 'domesticated' by their host as adaptations

184 e activation, identifying functions that are co-opted or abated to drive human cancers and developmen

185 nel modulatory mechanisms may potentially be co-opted or interfered with for therapeutic benefits.

186 In summary, the mammalian traffic machinery co-opts p-eIF2alpha and CReP, regulators of translation

187 Rather than co-opting pain circuitry, rejection involves distinct af

188 , highlighting the ability of tumor cells to co-opt pathways used for stem cell protection.

189 The co-opted PK generates high levels of ATP within the vira

190 The ATP generated by the co-opted PK is used to promote the helicase activity of

191 e not built from scratch, but rather form by co-opting preexisting gene networks.

192 rus production and spread, some viruses have co-opted prosurvival genes from the host.

193 receptor impinges on a signaling pathway by co-opting protein kinase docking sites to constitutively

194 Our findings demonstrate that EBV can co-opt Rad18 as a novel accessory factor in the producti

195 ription factors, and nontranscriptionally by co-opting redox oscillations.

196 reveals that, contrary to the expectation of co-opting regulatory mechanisms readily in place, the ev

197 Our findings suggest that host genomes co-opt retroelement activity in the germline to create n

198 Overall, this work demonstrates that the co-opted Rpn11p, which is involved in the assembly of th

199 ng et al., (2017) demonstrate how host cells co-opt sequential action of autophagy proteins and IFN-i

200 NPM-ALK co-opts several intracellular signal transduction pathwa

201 ntiviral interferon-stimulated genes, and by co-opting SG proteins for its replication, assembly, and

202 At the molecular level, TBL1XR1 mutants co-opt SMRT/HDAC3 repressor complexes toward binding the

203 ecific transcription factor is sufficient to co-opt somatic transcriptional machinery to drive a pro-

204 Glioblastomas co-opt stem cell regulatory pathways to maintain brain t

205 Despite co-opting STING to promote its replication, interferon s

206 nario where kin- and other indirect benefits co-opt strategies originally evolved for mind-reading, a

207 erapeutics, small hairpin RNAs (shRNAs) must co-opt sufficient quantities of the endogenous microRNA

208 Thus, nanotherapeutics co-opt TAMs for drug delivery, which has implications fo

209 ges of the early mouse embryo have seemingly co-opted TEs as enhancers, but there is little evidence

210 One solution to this problem would be to co-opt the "temporal" guidance mechanisms that control t

211 s converge to demonstrate that androgens can co-opt the AMPK-PGC-1alpha signaling cascade, a known ho

212 Thus, tumors co-opt the ancient survival functions of HSF1 to orchest

213 ariant natural killer T (NKT) cells can also co-opt the Bcl-6-dependent follicular differentiation pa

214 Viruses must co-opt the cellular translation machinery to produce pro

215 oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain

216 poliovirus (PV), and enterovirus 71 (EV71), co-opt the host cell secretory pathway, which controls t

217 support to the following scenario: bacteria co-opt the host transporter SLC35D2 to import UDP-glucos

218 MM cells may co-opt the IRE1alpha-XBP1s pathway; however, the validit

219 t a mechanism for the malignancy in order to co-opt the microenvironment and suggest separate mesench

220 nce demonstrate that general anesthetics can co-opt the neural circuits regulating arousal to produce

221 ble focus on the hypothesis that anesthetics co-opt the neural mechanisms regulating sleep.

222 Brain tumor initiating cells (BTICs) co-opt the neuronal high affinity glucose transporter, G

223 ndochitinase A is a unique way an insect can co-opt the plant's defense proteins for its own benefit.

224 (G147R) that enables an N1 NA to completely co-opt the receptor-binding function normally performed

225 The concept that tumor-initiating cells can co-opt the self-renewal program of endogenous stem cells

226 are beginning to reveal the ways that cells co-opt the structures of the nuclear periphery for nucle

227 We co-opted the aberrant reproductive process of haploid in

228 Viruses have also co-opted the MHC fold for immune-evasive functions.

229 We propose that herpesviruses may have co-opted the MTC functionality of UL37 to bring capsids

230 Viral pathogens have also extensively co-opted the OTU fold to subvert host signaling, but the

231 We show that the spot enhancer has co-opted the sequences of the wing blade enhancer.

232 tome ancestor and that smooth myocytes later co-opted the striated contractile module repeatedly - fo

233 b for VRCs, likely in collaboration with the co-opted the syntaxin18-like Ufe1 SNARE protein within t

234 trast enhancing and integrative functions by co-opting the capacities of the two cerebral hemispheres

235 pproach to targeted therapy that is based on co-opting the cellular quality-control machinery-the ubi

236 ies that have evolved dosage compensation by co-opting the dosage-compensation male-specific lethal (

237 BTICs outcompete for glucose uptake by co-opting the high affinity neuronal glucose transporter

238 circulating proteins to their own surfaces, co-opting the host protein functions as a mechanism of v

239 xits from polarized host intestinal cells by co-opting the host vesicle trafficking system and escapi

240 l, increased ELF5 levels drive metastasis by co-opting the innate immune system.

241 ars ago (Mya), whereas Cf-2 evolved <6Mya by co-opting the pre-existing Rcr3 in the Solanum genus.

242 Our results also show that co-opting the sulphur-delivery machinery of primary meta

243 to the ribosome and initiate translation by co-opting the translation elongation cycle.

244 centrations at a post-translational level by co-opting the ubiquitin-proteasome system.

245 In an unusual twist, human cytomegalovirus co-opts the antiviral radical SAM enzyme viperin (virus-

246 We find that TBSV co-opts the cellular glycolytic ATP-generating pyruvate

247 To induce the degradation of SAMHD1, Vpx co-opts the cullin4a-based E3 ubiquitin ligase, CRL4.

248 by binding a portion of cholera toxin as it co-opts the ER to cause disease.

249 his paper, the authors demonstrate that TBSV co-opts the guanosine triphosphate (GTP)-bound active fo

250 cete pathogen Hyaloperonospora arabidopsidis co-opts the host cell's nuclear import machinery.

251 Here, we show that hepatitis C virus (HCV) co-opts the host protein CypA to aid evasion of antivira

252 This study examined whether HIV co-opts the normal T cell activation process through the

253 The viral polymerase complex co-opts the nuclear RNA exosome complex and cellular RNA

254 The system co-opts the orthogonal autoinducer AI-1 and AI-2 cell-ce

255 MCs co-opt their secretory granules for antigen processing a

256 rks from their normal B-cell counterpart and co-opt them for their own oncogenic purpose, which is us

257 ties of phage genes for their own benefit by co-opting them as toxins for functions related to bacter

258 ma and Neospora use a conserved mechanism to co-opt these host organelles, which suggests that lipid

259 Drugs of abuse co-opt these neural pathways, which can lead to addictio

260 oles in regulating RNA function, and viruses co-opt these pathways for their own benefit.

261 How cancer cells co-opt this process to promote tumorigenesis remains unc

262 Moreover, we show that co-opting this circuit by chemogenetic activation can cr

263 This research co-opts this crosslinking-mediated internalization for e

264 human immunodeficiency virus polyprotein Gag co-opts this process for budding of virus-like particles

265 Thus, commensal-specific T cells co-opt tissue residency and cell-intrinsic flexibility a

266 The hypothesis that EVs may be critical in co-opting tissues by tumours to generate distant metasta

267 We report that the HoxC gene cluster was co-opted to be transcribed in the distal limb ectoderm,

268 E suppression, or mutualistic, where TEs are co-opted to benefit their host.

269 ncy in the earliest seed plants before being co-opted to control transpiration and CO2 exchange in de

270 ehavior in an ancestral protist may had been co-opted to develop some multicellular properties curren

271 nt polarity determination mechanism has been co-opted to different functions during evolution.

272 ism by which the innate immune system may be co-opted to drive tumor progression.

273 lts suggest that a lamin derivative has been co-opted to enhance tissue stability in tardigrades, a f

274 ggest that different HPAT homologs have been co-opted to function in diverse species-specific develop

275 he actin cytoskeleton during guidance can be co-opted to instruct synaptic vesicle clustering.

276 ave played an ancestral neural role, and was co-opted to its well-known essential germline role in ho

277 stimulation in most cells that express it is co-opted to negatively regulate pDC IFN-I production and

278 l in some contexts, but rather RISC has been co-opted to negatively regulate toxic host antiviral eff

279 rinsic growth cone guidance machinery can be co-opted to non-invasively build new connectivity, allow

280 ancestral gene lineages have been repeatedly co-opted to novel functions.

281 features that activate transcription can be co-opted to participate in the regulation of the splicin

282 Frequently co-opted to pattern new structures, the pathway is conse

283 nique chemistry that cyanobacteria have been co-opted to perform.

284 and the promoters for these genes have been co-opted to produce selective transgene expression withi

285 This trait may have then been co-opted to provide cancer resistance and longevity to t

286 ANP32A represents an essential host partner co-opted to support influenza virus replication and is a

287 Homeotic genes were subsequently co-opted to suppress growth of some dorsal flaps in the

288 sk how common metabolic regulators have been co-opted to the plant-pathogenic lifestyle as well as ho

289 tep is whether host cytosolic components are co-opted to transport the viral particle into the cytoso

290 for inhibition as in existing treatments, is co-opted to trigger therapeutic programs.

291 Finally, Ultrabithorax was co-opted to uncouple the morphology of T2 and T3 wings a

292 genome editing to determine the roles of two co-opted transcription factors that are expressed during

293 ots can be controlled by the activity of two co-opted transcription factors.

294 the expression patterns of haplotypes using co-opted transposon-derived sequences as regulatory elem

295 dows, we found that the type III-B machinery co-opts type I-F CRISPR-RNAs.

296 an independently evolved fungal complex that co-opted useful activities from bacterial neighbours wit

297 iveness along remaining blood vessels, which co-opts vessels in a VEGF-independent and neoangiogenesi

298 of ERV elements (ERVs) has been functionally co-opted via a stress-induced SUMO switch to augment ant

299 Our results uncover a novel role for co-opted viral genes, demonstrating that they are used t

300 acts as a transcriptional activator that has co-opted XPB to specifically target 15 EBV promoters tha