ライフサイエンスコーパス: coactivate

1 s were blocked when the other AR subtype was coactivated.

2 tion, cNkx-2.8 and serum response factor can coactivate a minimal cardiac alpha-actin promoter.

3 h Gal4-VP16 and EBNA1 strongly activated and coactivated a Gal4-VP16- and oriP-dependent promoter tha

4 The binary agonist MRS 1741 coactivated A(1) and A(3) receptors simultaneously, with

5 ranscriptional coactivator that binds to and coactivates a variety of transcription factors (TFs) to

6 t regulates a broad array of target genes by coactivating a whole host of transcription factors.

7 However, when coactivated, A-neuron posture dominates, limiting B-neur

8 TTP expression attenuates the coactivating activity of SRC-1, suggesting that exchange

9 ta(42) as well as Abeta(40), and appeared to coactivate alpha-, beta- and gamma-secretases, which are

10 bility of class I-restricted CD8+ T cells to coactivate and polarize DCs may support the induction of

11 Vav3 coactivates AR in a Vav3 pleckstrin homology (PH) domain

12 ctivity >1 Hz yielded two larger clusters of coactivated areas with an enlarged default mode network-

13 t, suggesting that in cells the two NPFs may coactivate Arp2/3 complex to initiate actin assembly.

14 Cortactin coactivates Arp2/3 complex synergistically with WASP-fam

15 Neurons in cortical circuits are often coactivated as ensembles, yet it is unclear whether ense

16 anterior cingulate cortex (ACC) are commonly coactivated as revealed by a meta-analysis, 2) AIC is fu

17 More importantly, when coactivated at different frequencies, the two commands p

18 PARP-1 coactivated B-Myb- and c-Myb-mediated transactivation of

19 Competing fate programs are coactivated before cells acquire fate-specific phenotypi

20 4-depleted cells and the ability of Vps15 to coactivate Bmal1-Clock independently of its complex with

21 ctional antagonist muscles, TA and Sol, were coactivated both in stimulated rats and in unstimulated

22 azetidine or the proteasome inhibitor MG132 coactivates both HSFs to different levels and hemin pref

23 In this study, we show that SNURF coactivates both wild-type estrogen receptor alpha (ERal

24 ts such as rosiglitazone and ciglitazone, is coactivated by 9 cis-retinoic acid and is inhibited by t

25 en connected over long distances, which were coactivated by a diverse range of experimental tasks.

26 Olfactory cortical neurons coactivated by a specific pattern of odorant evoked inpu

27 TRPM2 channels are coactivated by binding of intracellular ADP ribose and C

28 Furthermore, ERK1/2, when only coactivated by both IP3/Ca2+- and Homer1b/c-dependent pa

29 We found that ATGL alone or coactivated by comparative gene identification-58 effici

30 E2AD2 was specifically coactivated by EBNALP.

31 ereotyped combinations of glomeruli that are coactivated by odors, and certain combinations of glomer

32 in a failure of YY1 to interact with and be coactivated by PGC-1alpha.

33 promoter and activate it, predominantly when coactivated by PGC-1alpha.

34 hat function robustly only when HNF4alpha is coactivated by PGC-1alpha.

35 ation of Pdk4 transcription by PPARdelta was coactivated by PGC-1alpha.

36 d a Cl(-) channel in the transporter that is coactivated by protons and Cl(-).

37 homeobox gene) and either Hoxa7 or Hoxa9 are coactivated by retroviral integration in BXH2 murine mye

38 tral, and default-mode modules predominantly coactivated by specific cognitive domains (perception, a

39 NH(2)/COOH-terminal interaction and was not coactivated by SRC-1.

40 t various subsets of these components can be coactivated by stimulating the same area.

41 creased expression of oncomiR-3151, which is coactivated by the SP1/NF-kappaB complex.

42 e mechanism by which beta-catenin and TCF-4N coactivated C/EBPalpha appeared to involve p300, based u

43 (+)CD25(-) T cells is suppressed in vitro by coactivated CD4(+)CD25(+) T cells.

44 It also coactivates certain non-E2F transcription factors and pr

45 ng module (DUBm) of the SAGA transcriptional coactivating complex, as a SIRT1-interacting partner.

46 rgic synapses can be scaled in accordance to coactivated convergent glutamatergic input.

47 ed inputs revealed stronger synapses between coactivated cortical pyramidal neurons and neurons in th

48 An entrainment stimulus causes CRTC1 to coactivate CREB, inducing the expression of Per1 and Sik

49 p300 and/or CBP (p300/CBP) also coactivate CREB.

50 leukin-12 (IL-12) appears to be an essential coactivating cytokine for hepatic IFN-gamma expression.

51 Finally, the data indicate that compression coactivates distinct signaling pathways that may help de

52 cupy a majority of gene-regulatory elements, coactivating downstream targets.

53 and prefrontal cortex (PFC) are believed to coactivate during goal-directed behavior to identify, se

54 , while frontal and parietal areas typically coactivate during VSTM, maintenance of content in the fr

55 characterize two distinct networks typically coactivated during functional MRI tasks.

56 These sites are often coactivated during neuroimaging studies using semantic t

57 (DMN) is a distributed set of brain regions coactivated during resting states that is vulnerable to

58 ateral primary somatosensory cortex (SI) was coactivated during tactile stimulation of the right sole

59 tion (1) scaled the amplitudes of two bursts coactivated during the initial phase of wiping independe

60 (SMA) and the primary motor cortex (PMC) are coactivated during various breathing tasks.

61 1alpha interaction domain, was sufficient to coactivate EBNA2 in a gene-specific manner independent o

62 mphoma cells, we found that EBNA-LP strongly coactivated EBNA2 stimulation of LMP-1 and LMP2B RNAs, w

63 huttling in the heterokaryon assay yet still coactivates EBNA2 similarly to the smaller EBNA-LP isofo

64 ator of EBNA2 targets, but it preferentially coactivates EBNA2 stimulation of the viral divergent pro

65 The independent and coactivating effects of LPS were blocked by anti-TNF-alp

66 Clusters of coactivated enhancers and their target genes, known as s

67 Brain-wide analysis of highly coactivated ensembles following contextual fear discrimi

68 erminal (amino acids 576-1566) significantly coactivate ERalpha.

69 inding protein (TBP) and SNURF cooperatively coactivated ERalpha-mediated transactivation.

70 rogen responsive elements (pERE(3)), DRIP205 coactivates ERalpha-mediated transactivation.

71 ansfection studies, DRIP205Delta587-636 also coactivates ERalpha.

72 l3 was shown to synergize with PGC-1alpha to coactivate ERRalpha.

73 HDAC3 also functioned noncanonically to coactivate estrogen-related receptor alpha, inducing mic

74 Expression of PGC1A in H2.35 cells coactivated estrogen receptor 1 and was required for est

75 On the other hand, SORBS3 coactivated estrogen receptor alpha signaling, leading i

76 ing genes when stimulated in the presence of coactivated estrogen receptor-a, and this may underlie t

77 lation activity independently are capable of coactivating Ets-2.

78 y if it is assumed that hypertonic infusions coactivate excitatory and inhibitory synaptic inputs.

79 A proportionality or balance between coactivated excitatory and inhibitory inputs is often ob

80 nding endogenous activator protein, Gcn4, to coactivate expression of chromosomal reporter genes in S

81 anterior cingulate cortex (ACC) are commonly coactivated for cognitive saccade tasks, but whether thi

82 site and recruits Fhl3 to transcriptionally coactivate Foxk1 gene expression.

83 It also coactivates from the herpes simplex virus ICPO promoter

84 g neurons in the ascending auditory path and coactivated frontostriatal networks after hearing onset.

85 n their previously described transcriptional coactivating function, our study defines a switch in the

86 domains (TAD) play essential roles for their coactivating function.

87 pendent component analysis (eICA) identified coactivating functional networks and corresponding time

88 ion factors in Saccharomyces cerevisiae that coactivate genes necessary for growth in the absence of

89 epends on the ratio between the magnitude of coactivated glutamatergic and GABAergic inputs (E/I rati

90 ocalize within late endosomes, cotraffic and coactivate GSK3, which serves as a shared signaling node

91 as shown to physically interact and potently coactivate hepatic nuclear factor 4 and peroxisome proli

92 s inability to physically associate with and coactivate hepatic nuclear receptor 4alpha (HNF4alpha) a

93 RBPJ repressive complexes from enhancers to coactivate hes1 and arglu1 but not cd21 or cd23.

94 p220(NPAT), a substrate of cyclin E/CDK2, to coactivate histone genes during S phase.

95 eta requires its interaction with POU TFs to coactivate immune-related genes.

96 ide evidence that opponent social categories coactivate in face-processing regions, which compete and

97 k of frontal and parietal areas that usually coactivate in studies of working memory.

98 coding Hoxa9 and Meis1 are transcriptionally coactivated in a subset of acute myeloid leukemia (AML)

99 that PKA, MAPK, and MSK1, a CREB kinase, are coactivated in a subset of hippocampal CA1 pyramidal neu

100 addition, Bmi1 and the PI3K/Akt pathway were coactivated in a substantial fraction of human high-grad

101 er, both pathways are frequently found to be coactivated in cancer tissue.

102 When the two signals are coactivated in cells (i.e. tylapx/apx1), a new response

103 f extrinsic and intrinsic tongue muscles are coactivated in conditions of hypoxemia comparable to tha

104 ) intrinsic and extrinsic tongue muscles are coactivated in mild hypoxia, (2) airway occlusion increa

105 e tongue protrudor and retractor muscles are coactivated in response to hypoxia and hypercapnia, and

106 We hypothesized that multiple RTKs are coactivated in these tumors and that redundant inputs dr

107 t, but whether and how these 2 systems, when coactivated in vivo, interact with each other has not be

108 um, thalamus, and specific brainstem nuclei, coactivates in response to diverse experimental tasks an

109 s with the P-TEFb/CDK9 elongation factor and coactivates inducible genes, including HIV-1.

110 gnal for changes in the strength of a second coactivated input.

111 mutation were equivalent in their ability to coactivate integrin alphaIIbbeta3 in a CHO cell system w

112 As these regions frequently coactivate, it has been difficult to disentangle their r

113 ility of DDX5 to interact with RORgammat and coactivate its targets depends on intrinsic RNA helicase

114 DRIP150 coactivates ligand-dependent ERalpha-mediated transactiv

115 CD277 was secondary, serving as a mandatory coactivating ligand.

116 transcription factors Foxo1 and Pax5, which coactivated many pre-B cell genes, including Rag1, Rag2

117 urons also elicit the gastric mill rhythm by coactivating MCN1 and CPN2, but the GPR-elicited gastric

118 urons each elicit the gastric mill rhythm by coactivating MCN1 and CPN2.

119 MFs coactivate mGluR2/3 and mGluR1 in many UBCs, leading to

120 Moreover, p300/CBP coactivates Mi transcriptional activity in a manner depe

121 he cell's regulatory networks, and examining coactivated modules suggests specific instances of cross

122 The elevated expression of coactivating molecule CD40 as well as key adhesion molec

123 diated transcription seen in the presence of coactivating molecules and to the action of AR coinhibit

124 esponses of lymphocytes and the influence of coactivating molecules on these signaling processes is n

125 Signals provided by coactivating molecules such as CD4 and CD28 also influen

126 tions, and (c) the participation of specific coactivating molecules.

127 olish the ability of the full-length SRC1 to coactivate MR.

128 recombinant receptors, confirm that ESP7 can coactivate mu-opioid receptors (MOR) and SPRs in vitro.

129 that the glutamate rich C-terminus of ARGLU1 coactivates multiple nuclear receptors including the glu

130 show that the nervous system can voluntarily coactivate muscles to improve the quality of the haptic

131 However, how agrin and LRP4 coactivate MuSK remains unclear.

132 tionale for the selection of KRAS and PIK3CA coactivating mutations in a number of human malignancies

133 For E1A, P/CAF coactivates MYC, whereas both p300 and CBP suppress E1A

134 six prefrontal and eight other automatically-coactivated networks.

135 after optogenetic or electrical stimulation, coactivated neurons increased their correlated activity,

136 Coactivated neurons showed small biphasic changes in pre

137 tes since TRAF1 is unique among the TRAFs in coactivating NF-kappaB with LMP1(1-231), a TRAF2 dominan

138 ivation potentials of Kv4 that occurred upon coactivating NMDAR and group I metabotropic glutamatergi

139 ty and simultaneously blunt this response by coactivating NO synthase (NOS3) to enhance cGMP synthesi

140 n of E6-AP is dispensable for its ability to coactivate nuclear hormone receptors, showing that E6-AP

141 d kinase (ERK) kinase (MEK)/ERK pathway that coactivates one of the immediate targets of mTOR, p70 S6

142 1(WAF1/CIP1) and the ability for AP2alpha to coactivate p21 requires p53.

143 , an HDAC3 binding-deficient SMRT DAD mutant coactivated p53 transcriptional activity.

144 breast cancer invasiveness and metastasis by coactivating PEA3-mediated Twist expression.

145 hrough abrogation of the ability of PGC-1 to coactivate peroxisome proliferator-activated receptor ga

146 ith mRNA encoding Interleukin-27 (mIL-27) to coactivate PGC-1alpha, PPARalpha, and UCP-1, thereby pro

147 thin-language work showed that seeing a sign coactivates phonologically related signs, just as hearin

148 related signs, just as hearing a spoken word coactivates phonologically related words.

149 via autocrine or paracrine interaction with coactivated PlexinA2 and NRP1.

150 e POP-1/TCF beta-catenin binding domain, and coactivates POP-1-dependent transcription.

151 ed to the synapse to release D-serine, which coactivates postsynaptic NMDA receptors together with gl

152 g results, Bcl3 was shown to synergistically coactivate PPARalpha with PGC-1alpha in a manner similar

153 AR gamma coactivator 1 (PGC-1) is capable of coactivating PPARalpha in the transcriptional control of

154 s necessary and sufficient for PGC-1alpha to coactivate PPARgamma in the presence or absence of rosig

155 ability of each of these mutant proteins to coactivate PR or provide ubiquitin-protein ligase activi

156 nputs from different modalities, which, when coactivated, produced enhanced GC firing rates and disti

157 clear antigen (EBNA) leader protein (EBNALP) coactivates promoters with EBNA2 and is important for Ep

158 The coactivating properties of PIASx(alpha) require Elk-1 to

159 To test whether transcriptional coactivating properties were common to the rhesus LCV EB

160 r extracts, we identify the thyroid receptor coactivating protein (TRCp120), DMAP1, and the related M

161 Conditional disruption of the mTOR coactivating protein Raptor in developing mouse B cells

162 al change that allows for the interaction of coactivating proteins necessary for gene transcription.

163 entified including ones found in traditional coactivating proteins such as SRC1, SRC2, TRAP220, TRBP,

164 In the presence of T3, the TR recruits coactivating proteins that both modulate and integrate t

165 placement of corepressors and recruitment of coactivating proteins.

166 While the coactivating receptor DNAM-1 is involved in NK cell reco

167 ncreased expression of surface MHCII, T-cell coactivating receptors, and key cytokines/chemokine expr

168 lthough they did express ligands for NK cell coactivating receptors, NTB-A and 2B4.

169 performance of a recollection task known to coactivate regions of both networks.

170 There are relatively few materials whose coactivated response has been well-characterized.

171 rtnership and also influence each other when coactivated, resulting in nonadditive cross-inhibitory r

172 cells and Xenopus embryos, Wnt/Fz signaling coactivates Rho and Rac, another GTPase and distinct reg

173 ity of RVE8-LNK interaction, from a synergic coactivating role of evening-expressed clock genes to a

174 ombination of inhibitors targeting all three coactivated RTKs and MEK1 was needed to inhibit prolifer

175 ptional coactivator with PDZ-binding motif), coactivates Runx2-dependent gene transcription while rep

176 s, including actin cytoskeletal dynamics, by coactivating serum response factor.

177 The SRA RNA is a non-coding RNA that coactivates several human sex hormone receptors and is s

178 so associates with Dax-1 and synergistically coactivates SF-1 target gene transcription.

179 ns comprises related acetyltransferases that coactivate signal-responsive transcription.

180 hages (Mphi) or dendritic cells (DC) provide coactivating signals for the liver IFN-gamma response in

181 ds and, conversely, how hearing a word could coactivate signs and how such cross-language coactivatio

182 hrough dynamic competition between parallel, coactivated social categories that resolve into a stable

183 A-5 and GATA-6, were equivalent to GATA-4 in coactivating SRE-dependent targets.

184 ered downstream transcriptional responses by coactivating SREBP-1, which subsequently enhanced lipoge

185 ated transcription factor A [Mrtf-a]), which coactivates Srf-responsive genes downstream of Rho GTPas

186 activate STAT3 but the cleaved PC1 tail now coactivates STAT3 in a mechanism requiring STAT phosphor

187 -1 (Src-1) was specifically recruited by and coactivated Stat6 but not the chimeric Stat6 molecules.

188 receptor RNA activator (SRA) is an RNA that coactivates steroid hormone receptor-mediated transcript

189 n requires the Notch intracellular domain to coactivate Su(H)-mediated transcription of the Enhancer-

190 further participation of at least one of the coactivating substances.

191 In conclusion, coactivating TAA-specific CD4(+) T-helper cells with DCs

192 Among the PGC-1 coactivating targets, the expression of estrogen-related

193 tress-induced NKG2D ligands, such as MIC, by coactivating TCR signaling.

194 isoforms of the TFAP2 transcription factor, coactivating TFAP2-dependent transcription.

195 talization of infected B lymphocytes and can coactivate the EBV LMP1 promoter with EBNA2.

196 RNA helicase and stimulated their ability to coactivate the estrogen receptor, thereby potentially co

197 iate domain (TEAD) transcription factors and coactivate the expression of target genes, promoting cel

198 yr also disables the ability of kindlin-2 to coactivate the integrin.

199 Furthermore, EBNA3C m1 and m2 did not coactivate the LMP1 promoter with EBNA2.

200 nd type A (VWA) domain blocks the ability to coactivate the mating-specific MAPK Fus3.

201 For EBNA2, both P/CAF and CBP coactivate the MYC promoter, whereas p300 suppresses EBN

202 ecules that act as transcriptional adapters, coactivate the myogenic basic-helix-loop-helix (bHLH) pr

203 ndicates that SIRT1 and orthologous sirtuins coactivate the oestrogen receptor/ER and the worm steroi

204 The CAPER proteins coactivate the progesterone receptor in luciferase trans

205 inding defective mutant Nkx2-5pm efficiently coactivated the alphaCA promoter in the presence of SRF

206 SUMO-3, and the SUMO-conjugating enzyme UBC9 coactivated the LMP1 promoter with EBNA2.

207 SRC-2 expression in vitro Furthermore, SRC-2 coactivated the transcription factors GATA-binding prote

208 In tissue culture, PC-TP coactivated the transcriptional activity of Pax3.

209 ranscription factors RBP-Jkappa and PU.1 and coactivates the EBV LMP1 promoter with EBNA-2 in BL2 and

210 E6-AP also coactivates the hormone-dependent transcriptional activi

211 are at least two mechanisms by which EBNA-3C coactivates the LMP1 promoter with EBNA-2.

212 Instead, PGC-1alpha coactivates the orphan nuclear receptor ERR-alpha (oestr

213 These results suggest that BRCA1 selectively coactivates the p53 transcription factor towards genes t

214 SIRT1 deacetylates and coactivates the retinoic acid receptor beta, a known reg

215 PGC-1beta coactivates the SREBP transcription factor family and st

216 teracts with estrogen-bound ERs and strongly coactivates the transcription of target genes in culture

217 in (E6-AP/UBE3A) directly interacts with and coactivates the transcriptional activity of the human pr

218 expression; in addition, PGC-1 binds to and coactivates the transcriptional function of NRF-1 on the

219 directly regulate Mfn1 gene transcription by coactivating the estrogen-related receptor alpha on a co

220 w find that EBNA-3C is similar to EBNA-LP in coactivating the LMP1 promoter with EBNA-2 in non-EBV-in

221 expression, in large part, by binding to and coactivating the muscle-selective transcription factor M

222 Optogenetically coactivating the posterior amygdala (PA) terminals and V

223 tivity and found that the two areas strongly coactivate throughout the third trimester of pregnancy.

224 Coactivating TLR2 reduced the injurious effects of decti

225 and detection assay, that HSF1 and HSF2 are coactivated to different levels in response to a range o

226 hand in primary somatosensory cortex (SI) is coactivated to support learning of a difficult tactile d

227 ay transfer to untrained body parts that are coactivated to support tactile learning with the trained

228 Chameau and MBF1 cannot synergistically coactivate transcription due to competitive interactions

229 cells, P300 and CBP (but not PCAF) can also coactivate transcription mediated by the EBNA2 or VP16 a

230 activity of ErbB4, repressing its ability to coactivate transcription with Yes-associated protein.

231 kappaB inhibitors because it can function to coactivate transcription.

232 Moreover, whereas p68 robustly coactivated transcription from an estrogen response elem

233 A catalytically inactive topo I, which coactivated transcription, similarly stimulated the rapi

234 ata strongly support a model in which EBNALP coactivates transcription by relocalizing HDAC4 and 5 fr

235 that ectopic overexpression of TRAP220/MED1 coactivates transcription from the Aurora-A gene promote

236 , both represses transcription from P(A) and coactivates transcription from the divergent P(R).

237 In addition, CoAA potently coactivates transcription mediated by multiple hormone-r

238 tly guides phyA to target gene promoters and coactivates transcription.

239 potential combinations of candidate factors, coactivating transcription factors Pax3 and Zic1 not onl

240 amily, is capable of substituting for Sp1 in coactivating transcription from all three of these promo

241 rial promoters and phage early promoters and coactivating transcription from phage middle promoters.

242 rast to tumors activating SHH but not CXCR4, coactivated tumors exhibited greater expression of Math1

243 Furthermore, SRC-1 was found to coactivate Twist transcription through physical interact

244 hat the protrudor and retractor muscles were coactivated under both conditions.

245 modulators share a synthesis pathway and are coactivated under states of arousal, they engage in dist

246 res are resolved through competition between coactivated ventral-temporal cortical representations wi

247 ein 1 promoter in lymphoblasts; EBNALP could coactivate with a deficient mutant EBNA2, EBNA2W(454)T,

248 gion, but either protein can synergistically coactivate with pX.

249 and CRP, suggesting that CRP could not fully coactivate with RhaS.

250 on to similar levels, CRP cannot effectively coactivate with RhaS.

251 specific: Sadness and anxiety-emotions that coactivate with shame-fail to track devaluation.

252 EBNA-3C can also coactivate with the EBNA-2 acidic activating domain; thi

253 ility was only modestly increased in T cells coactivated with anti-CD3 and anti-CD28 at 5 h and not i

254 ndogenous IL-10 and further amplified in MCs coactivated with both IL-33 and IgE/Ag.

255 isoforms of NFX1 were found: NFX1-123, which coactivated with c-Myc at the hTERT promoter, and NFX1-9

256 more, EBNA3C amino acids 476 to 992 potently coactivated with EBNA2 but EBNA3C amino acids 516 to 922

257 Marshall nerve activity were preceded by or coactivated with ECNA (stellate ganglion nerve activity

258 Depending on the receptor complex, Tyk2 is coactivated with either Jak1 or Jak2, but a detailed mol

259 We found a group of neurons that were coactivated with extensors during PLRs before RS and exh

260 potentiation at thalamoreticular inputs when coactivated with GluN2B-containing NMDA receptors, which

261 resent study, we explored molecular pathways coactivated with Gro-1/KC, and identified a transcript t

262 k-related increases, either independently or coactivated with other regions in the network.

263 In cases of AML where MET is coactivated with other tyrosine kinases, such as fibrobl

264 emporal order in which the parallel fiber is coactivated with the climbing fiber input, but how order

265 -regulate expression of p27(Kip1), even when coactivated with the Janus kinases (Jak) or the Raf/Erk

266 ficantly increased IgG production by B cells coactivated with TI-2 Ag and adjuvant, suggesting iNKT-i

267 nscription coactivator p300/CBP binds to and coactivates with both p53 and p73 in stimulating the exp

268 Results also demonstrate that LIPC coactivates with dissociable posterior regions depending

269 Furthermore, this brain area strongly coactivates with other reward-associated regions identif

270 as associated with VR reduction only when it coactivates with the IVC-IAGPNA.

271 gauge whether (and how) seeing a sign could coactivate words and, conversely, how hearing a word cou