ライフサイエンスコーパス: coactivation

1 especially during periods of sensory-evoked coactivation.

2 ng of the complex and dynamic process of RTK coactivation.

3 R boxes of DRIP205 are not required for this coactivation.

4 omes and cancer phenotypes downstream of RTK coactivation.

5 bset of the ERalpha cistrome associated with coactivation.

6 ting them indirectly through augmented SRC-1 coactivation.

7 R may be the basis for the difference in CRP coactivation.

8 mer are different from those obtained during coactivation.

9 ndent activation as well as EBNALP-dependent coactivation.

10 his does not correlate as closely with Gcn5p coactivation.

11 st that Sp100 is a major mediator of EBNA-LP coactivation.

12 between AP2alpha binding and transcriptional coactivation.

13 oles in EBNA2-mediated activation and EBNALP coactivation.

14 bilized association with EBNA2 and prevented coactivation.

15 that amino acids 476 to 515 are critical for coactivation.

16 ility of the EMG, as well as flexor-extensor coactivation.

17 e modeling was used to examine network-level coactivation.

18 ort of the biological relevance of PI(4,5)P2 coactivation, a yeast mutant with reduced PI(4,5)P2 leve

19 ed1 stimulates its intrinsic transcriptional coactivation activity.

20 3-amino-acid sequence (789-811) required for coactivation activity.

21 Muscle activity and coactivation also decreased with motor learning.

22 erase (CARM1/PRMT4)-mediated transcriptional coactivation and arginine methylation is known to regula

23 d picture with MD regions as a whole showing coactivation and broad rule representation, but with sig

24 mic mutants are inactive for transcriptional coactivation and cancer cell growth.

25 ome-wide binding profiles for ER and GR upon coactivation and characterized the status of the chromat

26 We propose that the coactivation and competition modes mediated by the 3'RR

27 of 3'RR-mediated activation of I promoters: coactivation and competition.

28 tor translation for target selection through coactivation and competitive interaction of neural popul

29 anscriptional activity, suggesting that both coactivation and corepression are involved.

30 as competing effects on p53 activity through coactivation and decreased stability.

31 3-linked ubiquitin chains in transcriptional coactivation and demonstrate that atrogin-1 uses this me

32 A phenocopied restoration of pRB function in coactivation and differentiation assays, suggesting that

33 e needed to determine whether the changes in coactivation and modularity that are associated with alc

34 sites is a fundamental determinant of their coactivation and of synaptic physiology.

35 research stresses the importance of receptor coactivation and signal integration during development o

36 This work highlights the effect of receptor coactivation and signal integration in a developmental s

37 activation is involved after the PKC and PKA coactivation, and intrathecal administration of bradykin

38 h as cell-cycle progression, transcriptional coactivation, and mRNA processing.

39 nscriptional activation and regulated EBNALP coactivation are critical for Epstein-Barr virus-infecte

40 cleotide excision repair and transcriptional coactivation as a critical component of the NANOG, OCT4,

41 ly identified receptor tyrosine kinase (RTK) coactivation as an important mechanism by which cancer c

42 gely rule out the static set and alpha-gamma coactivation as the main types of fusimotor drive that t

43 correspondence with patterns of task-evoked coactivation as well as maps of anatomical connectivity.

44 tions of AIB1 that are independent of its ER coactivation, as both approaches, ovariectomy and ER-/-

45 caudal trunk motor areas expanded; (2) trunk coactivation at cortex sites increased; (3) richness of

46 nistein, equol, and bisphenol A, whereas its coactivation at the AP-1 site is augmented by fulvestran

47 Recent advances now compute coactivation-based connectivity, connectivity-based func

48 Consistent with EBNALP coactivation being mediated by nuclear HDAC4 depletion,

49 the dynamic behavior of Dcp2 and attenuates coactivation by a yeast enhancer of decapping (Edc1).

50 Coactivation by Dax-1 is abolished by SRA knockdown.

51 heterodimerization with RXR is required for coactivation by DRIP205.

52 ections revealed during spontaneous activity coactivation by GCaMP3 were confirmed by intracortical m

53 Axons respond synergistically to coactivation by GDNF and EphA ligands, and these coopera

54 the livers of uninfected mice and depend on coactivation by IL-12 and IL-18 for optimum responses.

55 y toward target cells depends on synergistic coactivation by NK cell receptors such as NKG2D and 2B4.

56 intrinsic inhibitory function of RD1 and for coactivation by PIASxalpha and PIASxbeta, two members of

57 ine-specific activator sites (A1) as well as coactivation by substrate dNTP binding to a distinct set

58 n MOR-Tyr166p immunoreactivity (ir) required coactivation by the opioid agonist [D-Ala(2),methyl-Phe(

59 acid respectively to increase ER and DAF-12 coactivation by the sirtuins.

60 Accelerated hepatic DNL was due to coactivation by Vpr of liver X receptor-alpha (LXRalpha)

61 each supply a surprising degree of redundant coactivation capacity in T cells and macrophages, althou

62 e H4 transcription factor (HINFP)/p220(NPAT) coactivation complex occurs in parallel with the CDK-dep

63 lly interacts with the Notch transcriptional coactivation complex through C promoter-binding factor 1

64 We found spontaneous neuronal coactivations corresponded to intracellular UP states.

65 ata-driven approach, we analyzed large-scale coactivation data from 5,809 human imaging studies.

66 of the EBNA-LP mutants tested, including the coactivation-deficient DeltaCR3 mutant and the nonshuttl

67 tein that contains, besides other domains, 2 coactivation domains for the transcription factor Runx1/

68 ed firing during exploration showed stronger coactivation during eSWRs and subsequent sleep-SWRs.

69 g swing, and increased antagonist leg muscle coactivation during limb loading in early stance, and (2

70 -demand (MD) regions of the human brain show coactivation during many different kinds of task perform

71 , and showed increased bursting and temporal coactivation during postexperience sleep.

72 y of muscle modes that reflected lumbopelvic coactivation during the lifting phase compared to contro

73 ring rest reflected the level of their prior coactivation during the NF epoch.

74 Second, CF and PF coactivation evoked localized supralinear dendritic calc

75 omatin remodeling, histone modification, and coactivation factors.

76 This asymmetric timing window for coactivation follows the kinetics of calcium removal and

77 ining the AR-interacting FXXLF motif without coactivation function can suppress HF-enhanced AR transa

78 result, at least in part, from its defective coactivation function for HNF4alpha.

79 eceptor coactivator 1 (SRC-1) and that UBCH7 coactivation function is dependent on SRC-1.

80 ous study suggested that some of the EBNA-LP coactivation function is mediated by relocalizing histon

81 both required for the mutual interaction and coactivation function of Brd4.

82 This finding indicates that the coactivation function of c-Jun is sufficient for regulat

83 ttling is not required for efficient EBNA-LP coactivation function, and that competence for HDAC4 ass

84 Thus, inhibition of the coactivation-function of Stat3 resulted in suppression o

85 ower occurred even after muscle activity and coactivation had stabilized and movement changes were sm

86 The "alpha-gamma coactivation" hypothesis states that activity in a muscl

87 attenuates MUC1-induced (i) transcriptional coactivation, (ii) anchorage-independent growth, and (ii

88 ent functional imaging studies have revealed coactivation in a distributed network of cortical region

89 ay be useful in assessing the role of EBNALP coactivation in LCL growth or survival.

90 ate nuclear-cytoplasmic shuttling or EBNA-LP coactivation in the absence of a functional interaction

91 hysiological significance of transcriptional coactivation in the context of signal-dependent and cell

92 the recovered AN group, displayed increased coactivation in the left parietal cortex, encompassing t

93 Coactivation in the motor cortex and supplementary motor

94 er opioid hotspot required permissive opioid coactivation in the other (behaviorally).

95 K (mitogen-activated protein kinase) pathway coactivation in the prostate epithelium promotes both ep

96 Empathy often involves coactivations in further networks associated with social

97 D1Rs and D2Rs are not colocalized but their coactivation is necessary.

98 We hypothesized that spontaneous interareal coactivation is subserved by neuronal synchronization.

99 provided evidence that such social category coactivation manifested in neural patterns of the right

100 Meta-analytic coactivation maps of task-related increases were indepen

101 n vitro resulted in higher expression of the coactivation markers CD80, CD40, and CD70 on dendritic c

102 This continuous coactivation matrix was used to build a weighted graph t

103 This coactivation may be important for postprandial nutrient

104 These results imply multiple distinct RTK coactivation mechanisms and support the notion that smal

105 on of at least two different cAMP-responsive coactivation mechanisms.

106 mature DCs, the expression of CD80 and CD86 coactivation molecules, the production of IL-12p70 requi

107 The coactivation network was modular, with occipital, centra

108 Many aspects of the coactivation network were convergent with a connectivity

109 riven by nonmutated receptor tyrosine kinase coactivation networks that defy full inhibition with sin

110 explanation for paradoxical pallidothalamic coactivations observed during behavior that raises new q

111 Coactivation of 5-HT1A and GRP receptors (GRPR) greatly

112 Coactivation of a few 10s to 100s of neurons can code se

113 This was followed by coactivation of a frontal-parietal system [superior fron

114 tivity among a large proportion of inputs or coactivation of a smaller subset of local dendrodendriti

115 o distinct biochemical activities, including coactivation of adipose triglyceride lipase and acylatio

116 can respond to glutamate spillover following coactivation of adjacent parallel fibers (PFs), indicati

117 ng mnemonic and executive tasks requires the coactivation of adult prefrontal and hippocampal network

118 dpoints are best explained as resulting from coactivation of agonist and antagonist muscles driving t

119 y step cycle and consequently there was less coactivation of agonist and antagonist muscles during th

120 a cortical origin for myoclonus and striking coactivation of agonist and antagonist muscles.

121 The biological effects of coactivation of AKT and N-Ras were then recapitulated in

122 emergence of mesenchymal components and the coactivation of AKT and STAT pathways as well as PTEN in

123 We found that coactivation of alpha(1A)- and beta(2)-AR by the nonsele

124 f events exhibiting the kinetics expected of coactivation of alpha7-nAChRs and alpha3-nAChRs.

125 thway by transactivating erbB1 receptors via coactivation of AMPA receptors (AMPARs) and metabotropic

126 teroid receptor activation within HVC; local coactivation of androgen and estrogen receptors (ARs and

127 ibition in M1, which is associated with high coactivation of antagonistic muscle groups.

128 lloproteinase (MMP)-2 and MMP-13 through its coactivation of AP-1 and PEA3.

129 of a c-Jun mutant, which is fully active in coactivation of AR but deficient in AP-1 transactivation

130 Coactivation of areas implies functional connections but

131 Coactivation of astrocytic AMPARs and mGluRs caused extr

132 case in which the main contribution was from coactivation of biarticular muscles.

133 silateral ascending influences that ensure a coactivation of bilateral extraocular motoneurons with s

134 branch of the decision tree involves initial coactivation of bipotential properties followed by gradu

135 nor AKT alone promoted S-phase progression, coactivation of both kinases elicited a robust prolifera

136 iated currents in lamina II neurons requires coactivation of both PKC and PKA.

137 Coactivation of both receptors led to the canonical nega

138 Furthermore, coactivation of both receptors via repetitive afferent s

139 se correlations reflect the prior history of coactivation of brain regions, then a marked shift in co

140 e but, more importantly, to induce effective coactivation of CD4 T cells.

141 Coactivation of cold- and heat-responsive sensory neuron

142 tic network evoked activity, with systematic coactivation of cortical areas which are components of t

143 f WWOX and ErbB-4 suppresses transcriptional coactivation of CTF by YAP in a dose-dependent manner.

144 SRCAP is implicated in the transcriptional coactivation of cyclic AMP- and steroid-dependent promot

145 PPARgamma coactivator-1 alpha (PGC-1 alpha) coactivation of CYP7A1 reporter activity, whereas a domi

146 icated that this is mediated by AC5, because coactivation of D(2) and mGluRs could induce LTD in wild

147 the catalytic domain of Dcp2, and show that coactivation of decapping by Dcp2 is linked to formation

148 vating receptors, such as 2B4 or CD16, or by coactivation of different receptor combinations.

149 e cohort of clinical samples showed frequent coactivation of EGFR and SFKs in glioblastoma patients.

150 ALK secondary mutation but instead harbored coactivation of EGFR signaling.

151 However, PIASx-mediated coactivation of Elk-1 occurs in an E3 activity-independe

152 K for survival, it also contained concurrent coactivation of epidermal growth factor receptor (EGFR)

153 Moreover, coactivation of ER and IKKbeta promoted cell migration a

154 Taken together, our findings suggest that coactivation of ER and the canonical NFkappaB pathway pr

155 tiple domains of this protein play a role in coactivation of ERalpha and in interactions with ERalpha

156 These results demonstrate that coactivation of ERalpha by DRIP150 in ZR-75 cells is NR

157 Coactivation of ERalpha by DRIP150 in ZR-75 cells was ac

158 Coactivation of ERalpha by DRIP205 does not require NR b

159 ; however, unlike p160 coactivators, DRIP205 coactivation of ERalpha does not require NR boxes.

160 ining these sequences were not necessary for coactivation of ERalpha.

161 nteraction with ErbB-4 has no effect on this coactivation of ErbB-4.

162 HDAC3 coactivation of ERRalpha is mediated by deacetylation of

163 , all phosphorylation sites are required for coactivation of estrogen and androgen receptors, but not

164 helia and is required to modulate AIB1/SRC-3 coactivation of estrogen receptor alpha (ERalpha), proge

165 Coactivation of FGFR1 and FGFR3 promoted symmetrical div

166 nclude that neuronal ensembles, built by the coactivation of flexible groups of neurons, are emergent

167 interaction participating in transcriptional coactivation of genes encoding G(1) phase regulatory pro

168 The coactivation of GIRK and SK channels represents a novel

169 Moreover, during resting behavior, coactivation of hippocampal cells in sharp-wave/ripples

170 Coactivation of human NK cells via CD16 and IL-12 induce

171 ation of extrinsic tongue muscles but by the coactivation of intrinsic and extrinsic protrudor and re

172 s and that memories are instead coded by the coactivation of invariant and context-independent engram

173 and in xenografted mice was dependent on the coactivation of JAK2/STAT3 and MEK/ERK1/2 in neuroblasto

174 nduction, and investigated the net effect of coactivation of M(1) and alpha1 receptors on the magnitu

175 Coactivation of mAChRs and mGluRs also induced a long-la

176 These findings provide a mechanism for LGP2 coactivation of MDA5 and a biological context for MDA5-R

177 interaction with LGP2 specifically prevents coactivation of MDA5 signaling and that LGP2's negative

178 Coactivation of mGluR1/5 and DR1/5 also enhanced cAMP-re

179 Coactivation of mGluR1/5 and DR1/5 with (S)-3,5-dihydrox

180 iably represented by momentary, simultaneous coactivation of microbands of adjacent Purkinje cells.

181 Coactivation of MOR and SSTR2 in PDAC cells led to incre

182 types, such as cardiomyocytes, this leads to coactivation of multiple downstream pathways.

183 inherent resistance mechanism in GBM is the coactivation of multiple receptor tyrosine kinases, whic

184 t that, in the absence of direct experience, coactivation of multiple relevant memories can provide a

185 ivation often overlaps and crosstalk between coactivation of multiple signaling cascades can result i

186 We found that coactivation of N-methyl-D-aspartate receptors (NMDAR) a

187 We found that coactivation of N-methyl-D-aspartate receptors (NMDARs)

188 Coactivation of N-methyl-D-aspartate receptors (NMDARs)

189 Coactivation of neighboring cells enhances the activatio

190 Coactivation of neonatal moDCs through Dectin-1 allows T

191 tial diffusion will determine the convergent coactivation of neuroblasts and stem cells, and provide

192 Here, we tested whether coactivation of neurons across macaque ACC and PFC would

193 n effect commonly interpreted to reflect the coactivation of neurons due to anatomically shared input

194 eceptors, but not all sites are required for coactivation of NF-kappaB.

195 novel function of GITR/GITRL in pDC-mediated coactivation of NK cells.

196 This potentiation requires coactivation of NMDA and mGlu5 receptors and a postsynap

197 This form of plasticity requires coactivation of NMDA receptors (NMDARs).

198 Our results provide evidence that D-serine coactivation of NMDA receptors and endothelial nitric ox

199 ynergistic phosphorylation of ERK induced by coactivation of NMDA receptors and mGluR5 was blocked by

200 Coactivation of Notch allows accumulation of far greater

201 this coregulator, thereby facilitating SMRT coactivation of p53-dependent gene expression.

202 Furthermore, WWOX is able to inhibit coactivation of p73 by YAP.

203 pmental program results from the reiterative coactivation of pathways that are largely inactive in ve

204 Compared to PF stimulation alone, coactivation of PF and CF synapses greatly enhanced endo

205 es prostate cancer metastasis in response to coactivation of PI3-kinase and Ras signaling pathways in

206 his transcriptional activity is required for coactivation of PPARdelta by ERK5 in C2C12 cells.

207 athways: (1) it increases FXR mRNA levels by coactivation of PPARgamma and HNF4alpha to enhance FXR g

208 owing that neural ignition (i.e., same trial coactivation of S1 and vPM) was more frequent in conscio

209 on) is processive during the transcriptional coactivation of select transcription factors and can ser

210 Coactivation of spinal alpha(2)-adrenergic receptors (AR

211 ring the early phase of PGC development, and coactivation of STAT and Ras is required for PGC prolife

212 h a dual intracellular cascade that requires coactivation of Stat6 and Stat1 to impact transcriptiona

213 anisms including methylation of histones and coactivation of steroid receptor transcription.

214 ence that motor plans in PMd emerge from the coactivation of such attractor modules, heterogeneous in

215 on of prosurvival signaling triggered by the coactivation of synaptic and extrasynaptic receptors.

216 SV-infected BMDC treated with GSK J4 altered coactivation of T cell cytokine production to RSV as wel

217 racts with beta-catenin and can suppress its coactivation of T cell factor 4 (Tcf4) in prostate cance

218 uman CCA cell lines, driven, in part, by YAP coactivation of TBX5.

219 Our findings show how coactivation of the AKT and CAT pathways in hepatocytes

220 In vitro, ZMIZ1 showed impaired coactivation of the androgen receptor.

221 Coactivation of the apoC-III/A-IV promoter region by PGC

222 ow that the nuclear localization of FHL2 and coactivation of the AR is driven by calpain cleavage of

223 that the responses were greatly increased by coactivation of the cells with either recombinant interl

224 mation required fast GABAergic transmission, coactivation of the dopamine D1 and NMDA receptor, and d

225 n alone causes long-term potentiation (LTP), coactivation of the heterosynaptic CF input, which evoke

226 Prominent coactivation of the hippocampus, detected in all groups,

227 ralized pain syndromes may be stress-induced coactivation of the hypothalamo-pituitary-adrenal and sy

228 The E2AD was essential for EBNALP coactivation of the latent membrane protein 1 promoter i

229 expression is likely due to the simultaneous coactivation of the liver X receptor, LXRalpha, a nuclea

230 After investigating the effect of coactivation of the NMDAR and the Gs-coupled beta-adrene

231 cognitive demand, patients showed increasing coactivation of the primary motor cortex and supplementa

232 single receptor activation, suggesting that coactivation of the receptors can lead to novel antagoni

233 ve mice to increase dopamine release through coactivation of the receptors CRFR1 and CRFR2.

234 l1 (Arntl) and Rev-erbalpha (Nr1d1), through coactivation of the ROR family of orphan nuclear recepto

235 subgroup of medulloblastoma characterized by coactivation of the Sonic hedgehog (SHH) and CXCR4 pathw

236 ve autonomic blockers, could be explained by coactivation of the sympathetic and cardiovagal outflows

237 erve stimulation elicited strong synergistic coactivation of the sympathetic and parasympathetic nerv

238 stic SF-1 and sex-determining region Y (SRY) coactivation of the testis development gene SOX9.

239 Coactivation of the TLR3 and TLR7 pathways synchronizes

240 Coactivation of the TTF-1 and NKX2-8 pathways identified

241 Furthermore, lung cancer cell lines showing coactivation of the TTF-1 and NKX2-8 pathways were shown

242 ng of prostanoid biosynthesis toward PGE2 by coactivation of the two enzymes.

243 Interestingly, coactivation of these receptors with the beta-adrenergic

244 d within a session, arguing against a simple coactivation of these regions.

245 ed) intensity to rule out the possibility of coactivation of this structure caused by the current spr

246 In contrast, the coactivation of TLR4 and IFN-gamma receptors results in

247 atients with Omenn syndrome, indicating that coactivation of TRAIL-R and TCR represents a mechanism t

248 is suggests that the cohort of patients with coactivation of TTF-1 and NKX2-8 pathways appears to be

249 ortantly, the poor prognosis associated with coactivation of TTF-1 and NKX2-8 was validated in 2 othe

250 specific effector function was stimulated by coactivation of Valpha14 iNKT cells using alpha-galactos

251 and that network events are composed of the coactivation of variable subsets of these clusters, whic

252 ions, we studied the effects of DA-glutamate coactivation on pyramidal cell excitability in brain sli

253 region, we parceled each region based on its coactivation pattern with the rest of the brain.

254 omotion (reciprocal innervation) and stance (coactivation pattern).

255 ation of GSCORR could be traced to transient coactivation patterns at the peak period of GS (GS-peak)

256 Manipulating coactivation patterns can alter perception in ways that

257 le spindles can contribute to shaping muscle coactivation patterns during reaching movements with com

258 Whether these coactivation patterns have any physiological reality wit

259 analyzing static GS correlation and dynamic coactivation patterns in a large sample of an fMRI datas

260 Neuron pairs exhibited coactivation patterns organized within beta-frequency ti

261 , we found that this brain area shows strong coactivation patterns with nearly all of the value-assoc

262 rest-task modulation, the underlying dynamic coactivation patterns, and its partial dissociation from

263 ain imparts a distinct signature on neuronal coactivation patterns.

264 The coactivation period of leg flexors and extensors, which

265 The coactivation potential of PGC-1alpha requires an intact

266 oylation mutant showed a drastically reduced coactivation potential.

267 on in Dcp2, suggest a structural pathway for coactivation, predict that Dcp1 directly contacts the ca

268 After such experimental coactivation, presynaptic firing evoked EPSCs of uniform

269 rovide structural insight into the versatile coactivation profile of PGC-1alpha and can readily be ex

270 ons were clustered based on their functional coactivation profiles across all the experiments stored

271 At the cellular level, Notch/Kras coactivation promotes rapid reprogramming of acinar cell

272 , mutagenesis of this docking site unearthed coactivation properties for FCRL5 that were orchestrated

273 of activation frequency, climbing fiber (CF) coactivation provides an instructive signal that further

274 y and decreased surface expression of CD2, a coactivation receptor.

275 Ligands of coactivation receptors 2B4 and NKG2D segregated into cen

276 en the nucleus and cytoplasm is required for coactivation remains to be clarified.

277 ne-specific coactivator of EBNA2 and whether coactivation requires interaction between these proteins

278 EBNALP coactivation requires the EBNA2 acidic activation domain

279 2X channels interact functionally, such that coactivation results in cross-inhibition of one or both

280 spatial scales on the basis of meta-analytic coactivation, revealing three broad functional zones alo

281 s RNA-binding domains in contexts related to coactivation, RNA-processing and possibly prokaryotic tr

282 Here, we demonstrate a specific ion coactivation (SICA) effect at the interfaces of transien

283 ize that a flexible receptor tyrosine kinase coactivation signaling network supports HNSCC survival i

284 ic pH at a physiological temperature provide coactivation signals, allowing virus association with me

285 tives take the form of time-invariant muscle coactivations ("spatial" synergies) or time-varying musc

286 xhibit a secondary effect that modulates the coactivation strength.

287 ear targeting of a Vav3 PH mutant rescued AR coactivation, suggesting that nuclear localization is an

288 ites SNr GABA neurons via D(1)-D(5) receptor coactivation that enhances constitutively active TRPC3 c

289 3) activation only in the context of P2Y(12) coactivation, thereby providing an additional temporal m

290 Simultaneous coactivation through Dectin-1 and TLRs induced robust se

291 These data suggested that Rac1 and Cdc42 coactivation was essential to smoke-promoted cell migrat

292 Two modes of coactivation were observed, one that was dependent on th

293 t stimulation-induced patterns of interareal coactivation were reactivated in the absence of stimulat

294 89%) were preceded by ICNA and sympathovagal coactivation, whereas 11% were preceded by ICNA and stel

295 ession repressed EBNA2 activation and EBNALP coactivation, whereas other HDACs had little effect.

296 al zones that exhibited discrete patterns of coactivation with cortical brain regions across distinct

297 EBNALP coactivation with EBNA2 was found to dominate over NCoR

298 ecause EBNALPd10 dominantly inhibited EBNALP coactivation with EBNA2, EBNALPd10 expression in LCLs ma

299 shown synergistic increases in signaling on coactivation with fibroblast growth factor 2 (FGF2) and

300 h motor learning and (2) muscle activity and coactivation would parallel changes in metabolic power.