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1 sion occurs through competition for a single coactivator protein.
2 occurs through increased binding to the p300 coactivator protein.
3 factor docking switches on the activity of a coactivator protein.
4 inding to and sequestering the p300 cellular coactivator protein.
5 ing protein (CBP), a transcriptional adaptor/coactivator protein.
6 and inhibited FoxM1B recruitment of the CBP coactivator protein.
7 n of necessary but different transcriptional coactivator proteins.
8 ociation of the GR with either remodeling or coactivator proteins.
9 in structure and the recruitment of receptor coactivator proteins.
10 stent with its inability to recruit receptor coactivator proteins.
11 ) that mediates hormone-dependent binding of coactivator proteins.
12 diated by distinct interactions with related coactivator proteins.
13 y conserved throughout the 300 or so natural coactivator proteins.
14 ve state conformation for optimal binding to coactivator proteins.
15 ors (RARs) competing for limiting amounts of coactivator proteins.
16 ich is essential for recruitment of p300/CBP coactivator proteins.
17 ssociates with transcriptional activator and coactivator proteins.
18 oncerted action of transcription factors and coactivator proteins.
19 th p300-CREB-binding protein transcriptional coactivator proteins.
20 tional activation by recruiting the p300/CBP coactivator proteins.
21 orepressors and promoting the association of coactivator proteins.
22 ther CARM1 can cooperate with other types of coactivator proteins.
23 s accomplished with the help of a variety of coactivator proteins.
24 several levels, including interactions with coactivator proteins.
25 xisome proliferator-activated receptor gamma coactivator protein 1alpha and stimulates hepatic glucon
26 xisome proliferator-activated receptor gamma coactivator protein-1alpha (PGC-1alpha), a key transcrip
27 antagonist due to ineffective recruitment of coactivator proteins and that enhanced coactivator recru
28 n regarding interactions between the LBD and coactivator proteins and the potential role of these int
29 of helix 12 and, thus, influence binding of coactivator proteins and their regulatory effect on tran
30 well as other biological processes, but both coactivator proteins are expressed in many other tissues
32 protein kinases, which associate with "Mob" coactivator proteins, are central but incompletely under
33 se during HF pathogenesis and identifies BET coactivator proteins as therapeutic targets in the heart
34 show that the C-terminal domain of the human coactivator protein ASC-1 defines a novel superfamily, t
36 cription through recruitment of the cellular coactivator protein CBP to the HTLV-I promoter, promotin
37 luding ATF-2, c-jun, Ets, Sp1, Egr-1 and the coactivator proteins CBP/p300 are recruited to the TNF-a
39 igations, we determine that recruitment of a coactivator protein, CBP (the CREBbinding protein), to t
40 uitment by nuclear receptors (NR) requires a coactivator protein, CCAR1 (cell-cycle and apoptosis reg
43 shed data, and it could be stimulated by the coactivator protein comparative gene identification-58 a
45 to NRs induces a conformation that attracts coactivator proteins containing an Leu-x-x-Leu-Leu motif
46 ive effects of these mutations on binding of coactivator proteins correlated with their cumulative ef
53 suggesting that a subset of T cell-specific coactivator proteins exist to selectively potentiate AP-
54 here that PPARgamma interacts with Hic-5, a coactivator protein expressed in gut epithelial cells.
57 in complex stimulates recruitment of the CBP coactivator protein for expression of Foxa2, a transcrip
59 ts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor an
61 studies have shown that the transcriptional coactivator protein Gcn5 functions as a catalytic histon
63 ity blocks the association of MEF2C with the coactivator protein GRIP-1 and thereby inhibits the acti
65 cognition domains (bromodomains) of putative coactivator proteins implicated in transcriptional initi
67 iption factors and p300/CREB-binding protein coactivator proteins in cytokine gene induction during T
68 TET2 bound the androgen receptor (AR) and AR-coactivator proteins in LNCaP cell extracts, and TET2 KD
70 ning helix 12 (H12) to facilitate binding of coactivator proteins in the unoccupied coactivator bindi
71 The significance of androgen receptor (AR) coactivator proteins in this androgen-dependent malignan
72 in the ability of ERalpha and ERbeta to bind coactivator proteins in vitro, despite the similarity in
73 ing of the nucleocytoplasmic distribution of coactivator proteins involved in transcription is an act
75 Consistent with the observed increase in coactivator protein levels, we were also able to observe
76 a loss in interaction between Vps4 with its coactivator protein LIP5 needed to promote the formation
78 l activation complex by interacting with the coactivator protein Mastermind-like 1 and the DNA bindin
79 in is required for activity of Notch and its coactivator protein, mastermind, during wing development
80 the ability of ERalpha and ERbeta to recruit coactivator proteins may contribute to the complex tissu
81 or (AR) transcriptional activity mediated by coactivator proteins may drive castration-resistant pros
86 e of corepressor proteins and the binding of coactivator proteins necessary for gene transcription.
87 enhanced p53 stability, implying that these coactivator proteins normally operate in p53 turnover co
88 he cyclin E/CDK2-dependent activation of the coactivator protein nuclear protein, ataxia-telangiectas
90 profiling of a retinoic acid receptor alpha coactivator protein, P/CAF, demonstrated elevated expres
91 drogen receptor (AR) and the upregulation of coactivator protein p300 and pioneer factors (e.g., GATA
96 inoblastoma tumor suppressor protein and the coactivator proteins p300/CBP (where CBP is the CREB-bin
98 ast to the interaction of PPARalpha with the coactivator protein, p300, association of the receptor w
99 dk5 was supported by adaptive changes in the coactivator protein p35 and by elevated glycogen synthes
101 FGF21, in turn, induces the transcriptional coactivator protein peroxisome proliferator-activated re
102 increased the mRNA and protein levels of the coactivator protein PGC1alpha, and this effect was depen
104 tor of nuclear receptors by modulating SRC-3 coactivator protein-protein complex formation and ultima
105 ity together with elevated levels of the CBP coactivator protein provided a 6.2-fold synergistic incr
106 likely the result of the concerted action of coactivator proteins recruited by the activators' short
107 iption, but also suggest that it can augment coactivator protein recruitment to at least some members
108 (CREB)-binding protein (CBP)/p300 family of coactivator proteins regulates gene transcription throug
110 on these results, we propose that a limiting coactivator protein(s) interacts with the AF-2 of PR or
114 n receptor alpha (ERalpha), steroid receptor coactivator proteins (SRC), and acetylated histones H3/H
115 C termini or recruitment of steroid receptor coactivator proteins (SRC-1 or -2), although SRC transfe
116 fects that different ERalpha ligands have on coactivator protein steady-state levels and demonstrate
118 Functional CAR:RXR heterodimers recruit coactivator proteins, such as the steroid receptor coact
120 itamin D receptor (VDR) and nuclear receptor coactivator protein that is unrelated to other VDR coact
121 ing to estrogen response elements (EREs) and coactivator proteins that act as bridging proteins betwe
122 k, we examine the roles of the Ada2 and Ada3 coactivator proteins that are functionally linked to Gcn
123 anscription involves chromatin remodeling by coactivator proteins that are recruited by DNA-bound tra
124 sses formation of astrocytes by sequestering coactivator proteins that are required by signal transdu
125 fied into an emerging set of transcriptional coactivator proteins that function to facilitate vitamin
126 studies have identified a universal motif in coactivator proteins that mediates association with rece
127 t at a FoxA-specific site, HNF-6 serves as a coactivator protein to enhance FoxA2 transcription, wher
128 ranscription factor (HNF-6) functioning as a coactivator protein to potentiate the transcriptional ac
130 LL motifs shown previously in other types of coactivator proteins to be essential for mediating NR bi
131 ranscription factors require transcriptional coactivator proteins to mediate their stimulation of tra
132 DNA-bound transcription factors recruit many coactivator proteins to remodel chromatin and activate t
133 sociated with their target genes and recruit coactivator proteins to remodel chromatin structure, rec
134 ith the C-terminal fragment of a coiled-coil coactivator protein, transforming acidic coiled-coil coa
135 toregulatory transcription factor, acting as coactivator proteins when ComK is present at low concent
137 D response elements in the DNA and specific coactivator proteins which help to initiate transcriptio
138 r molecule for the recruitment of additional coactivator proteins, which can finely regulate HBV tran
139 n of these transcription factors and the CBP coactivator protein with the endogenous mouse Foxa2 prom
140 ad, Nmi enhances the association of CBP/p300 coactivator proteins with Stat1 and Stat5, and together
141 the interaction of transcription factors and coactivator proteins with the promoter of steroidogenic
144 implicated the Hippo pathway transcriptional coactivator protein YAP1 as an additional driver of rela