ライフサイエンスコーパス: coat color

1 seen in yellow mice, including the change in coat color.

2 ult in obesity, hyperinsulinemia, and yellow coat color.

3 aganglionic megacolon associated with white coat color.

4 tes and partially restores the normal agouti coat color.

5 t produce visually striking changes in mouse coat color.

6 >9 widely distributed mammals with seasonal coat color.

7 icient melanosome transfer and a dilution of coat color.

8 ehavior, body composition, reproduction, and coat color.

9 these molecules giving rise to lighter skin/coat color.

10 he developing hair, leading to a dilution of coat color.

11 4 Andean beans genotypes with different seed coat colors.

12 acters of sesame seeds with four contrasting coat colors.

13 ancient DNA data associated with horse base coat colors.

14 s among the sesame seeds with different seed coat colors.

15 describe a bright coat color mutant, Bright coat color 1 (Bcc1), which develops light-colored hair a

16 ve numbers of brown, yellow, or intermediate coat color A(vy)/a offspring.

17 Cdk5 knockdown in mice causes a lightened coat color, a polarized distribution of melanin and hype

18 the hSCF220 transgene display a more severe coat color abnormality.

19 phenotypic and behavioral adaptations (e.g., coat color, aggression) that are not present in other Le

20 nfluencing alternative splicing patterns and coat color alterations.

21 o Collins paw preference in interaction with coat-color among females of a genetically heterogeneous

22 and F3 A(vy)/a offspring were classified for coat color, an indicator of A(vy) methylation.

23 by Corin plays a critical role in specifying coat color and acts downstream of agouti gene expression

24 able to reduce mismatch between the seasonal coat color and an increasingly snow-free background.

25 r show selection signatures, associated with coat color and behavior, in Neolithic herds despite recu

26 se coat color mutant mahoganoid (md) darkens coat color and decreases the obesity of A(y) mice that e

27 ying null alleles of dilute have a lightened coat color and die from a neurological disorder resembli

28 ific genomic differences in genes related to coat color and fat transport, which are likely associate

29 ding behavior in the trypanotolerant N'Dama, coat color and horn development in Ankole, and heat tole

30 in mast cells in vivo, and partially rescues coat color and mast cell defects in W(41) mice.

31 and mg suppressed the effects of Ay on both coat color and obesity.

32 ions in transgenic mice for their effects on coat color and obesity.

33 conspicuously among breeds, including size, coat color and texture, behavior, skeletal morphology, a

34 dilute alleles that vary in their effects on coat color and the nervous system.

35 Coat color and type are essential characteristics of dom

36 d beyond brief descriptions of a dilution of coat color and white spotting of the belly and extremiti

37 ic nervous system and does not affect renal, coat color, and retinal choroid development.

38 ation in two defining traits-tail length and coat color-and discovered a 41-megabase chromosomal inve

39 se, have been identified in mice by abnormal coat color, anemia, and germ cell defects.

40 stibular defects, and have variegated/dilute coat color as a result of pigmentation defects.

41 poson-mediated mutagenesis, which allows for coat color-based genotyping, we created mice in which th

42 All three mutations produce a lightened coat color because of defects in pigment granule transpo

43 us, exhibit a nearly complete restoration of coat color, but, surprisingly, melanosomes remain concen

44 us studies suggest that agouti causes yellow coat color by antagonizing the binding of alpha-melanocy

45 locus encoding a skin peptide that modifies coat color by antagonizing the melanocyte-stimulating ho

46 he 6- to 10-cM region surrounding the albino coat color (c = tyrosinase) locus on mouse chromosome 7.

47 the Prader-Willi/Angelman domain, an agouti coat color cassette was inserted into the downstream ope

48 ther plasticity in the initiation or rate of coat color change will be able to reduce mismatch betwee

49 latory region of Agouti to modulate seasonal coat color change.

50 Furthermore, coat color changed from normal brown to silver.

51 the melanocytes, and MC1R mutations causing coat color changes are known in many mammals.

52 Whereas coat color changes in the mouse mutants W (c-kit defect)

53 y discovered by genetic studies on the mouse coat color changes, and its deletion results in an itchy

54 us mutant ES cells were able to generate low coat color chimeric mice, only the wild-type allele was

55 ed size (length, width, and thickness), seed coat color, cotyledon color, hypocotyl color, stem growt

56 -of-function Kit phenotypes, including white coat color, decreased numbers of dermal mast cells, and

57 d Bace2(-/-) but not Bace1(-/-) mice display coat color defects, implying a specific role for BACE2 d

58 ozygous for the hSCF transgene demonstrate a coat color deficiency seen in some mice homozygous for m

59 me functional domains of agouti important to coat color determination are important for inducing obes

60 Chm(Flox), Tyr-Cre+ mice exhibited coat color dilution and pigment abnormalities of the RPE

61 by hearing loss, vestibular dysfunction, and coat color dilution.

62 F1 mice exhibit microphthalmia with complete coat color dilution.

63 eration of melanogenesis to result in marked coat color dilution.

64 ne, dilute suppressor (dsu), suppresses this coat color dilution.

65 o this endocrine-active compound shifted the coat color distribution of viable yellow agouti (Avy) mo

66 y an inversion at the locus determining seed coat color during domestication.

67 ed in genes regulating blood group antigens, coat color, fecundity, lactation, keratin formation, neu

68 ns identified as A. belzebul, based on their coat color, from both banks of the Xingu River and three

69 mplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted re

70 id (md) are negative modifiers of the Agouti coat color gene, which encodes a paracrine signaling mol

71 Unlike the situation for most coat color genes, there is no apparent homolog for Sex-l

72 Although the genetic basis of coat color has been well characterized, relatively littl

73 found evidence that some phenotypes, such as coat color, have experienced convergent adaptive introgr

74 s exhibit variable microphthalmia and patchy coat color hypopigmentation.

75 Here we leverage community science data on coat color in > 60,000 eastern gray squirrels (Sciurus c

76 e relation between variants of this gene and coat color in animals, suggests that the MC1R is an inte

77 modify this interaction to obtain different coat color in distinct environments are poorly understoo

78 tions of the KIT gene, responsible for white coat color in European pigs.

79 Skin pigmentation in humans and coat color in fleece-producing animals are regulated by

80 lecular cause of recessively inherited black coat color in hamsters (historically referred to as nona

81 Dun is a wild-type coat color in horses characterized by pigment dilution w

82 that acts in a paracrine manner to regulate coat color in mammals.

83 Reports that maternal diet influences coat color in mouse offspring carrying the agouti A(vy)

84 r, we show that a gene responsible for black coat color in the Large Munsterlander has a 40-Mb region

85 c interactions between two mice of different coat colors in their home cage.

86 mosaics-either visible (manifesting mottled coat color) in the scored generation (G2) or masked, amo

87 In Soay sheep, dark coat color is associated with large size, which is herit

88 nsible for 17 viable dilute alleles, a mouse-coat-color locus encoding unconventional myosin-VA.

89 Coat color maps to chromosome 2 where a strong candidate

90 ermline transmission can be scored through a coat color marker.

91 By incorporating mouse coat color markers into the vectors, we illustrate a wid

92 breeding to select for recessive and unusual coat colors may have concentrated this relatively rare a

93 were administered CTx followed by BMT using coat color-mismatched female donors.

94 wn loci and transposase transgenes exhibited coat color mosaicism, indicating somatic transposition.

95 )) at the mouse albino locus that results in coat-color mottling has been characterized at the molecu

96 ch are involved in local adaptations such as coat color, muscle development, metabolic processes, ost

97 The mouse coat color mutant mahoganoid (md) darkens coat color and

98 similar to those of the recently identified coat color mutant mahogany (Atrn(mg)).

99 Here, we describe a bright coat color mutant, Bright coat color 1 (Bcc1), which dev

100 The classical recessive coat color mutation misty (m) arose spontaneously on the

101 mahoganoid is a mouse coat-color mutation whose pigmentary phenotype and genet

102 sulted in over 100 years of intense study of coat color mutations in laboratory mice, thereby creatin

103 The d, ash, and ln coat color mutations provide a unique model system for t

104 at have been studied for decades using mouse coat color mutations.

105 Despite a large number of murine coat-color mutations, only one gene in humans, the melan

106 homozygous for the IDUA mutation and shared coat colors not recognized as normal for the breed by th

107 mutation at this locus, Ay, develop a yellow coat color, obesity, and diabetes, as the result of a de

108 phenotype characterized by a uniform yellow coat color, obesity, overgrowth, and metabolic derangeme

109 models in the field, we show that the light coat color of deer mice that recently colonized the ligh

110 , these results explain how dsu restores the coat color of dilute mice without restoring intracellula

111 me 15 and, at the same time, exhibit lighter coat color on their ears and tails, making this modified

112 ional myosin heavy chain locus cause diluted coat color, opisthotonic seizures, and death.

113 nd choline produced offspring with different coat colors or with kinked tails.

114 They will inform breeding efforts for seed coat color/patterning to improve consumer appeal in this

115 at may have contributed to the phenotypes in coat color patterns, body size, cashmere traits, as well

116 elanocortin signaling pathway and reveal how coat-color patterns and pigmentary diversity have been s

117 Without evolution in coat color phenology, the reduced snow duration will inc

118 e small GTPase Rab38 gives rise to the mouse coat color phenotype "chocolate" (cht), implicating Rab3

119 The dilute coat color phenotype is caused by irregular clumping of

120 The coat-color phenotype of young homozygous double-mutant m

121 ab38 and Tyrp1 produced mice with ocular and coat color pigment dilution greater than that seen with

122 he other that suggests a genetic basis for a coat color polymorphism in bears.

123 phism (SNP) genotyping, we associated winter coat color polymorphism to the genomic region of the pig

124 In contrast, seasonal coat color polyphenism creating camouflage against snow

125 an agouti allele (A(iapy)), which provided a coat color readout for the methylation status of the IAP

126 Moreover, in the case of seed coat color rescue, AtPLC1 overexpression restored expres

127 d several lines of transgenic mice exhibited coat colors resembling dominant Agouti allele phenotypes

128 during storage period contribute to the seed coat color saturation.

129 anosomal forms, leading to the hypopigmented coat colors seen in these strains.

130 tigated both the DNA methylation changes and coat color shift in the irradiated offspring.

131 ts homozygous for this mutation (sl) exhibit coat color spotting and congenital intestinal agangliono

132 The transgene has no effect on coat color spotting, indicating the critical time for ED

133 tant mice considerably darkened their yellow coat color suggesting a previously unreported role for e

134 mutants of M. truncatula exhibit darker seed coat color than wild-type plants, with myb5 also showing

135 outi associated with survival causes lighter coat color through changes in its protein binding proper

136 d congenic mice of black, yellow, and albino coat colors to investigate the induction of DNA lesions

137 round, which yields a phenotypic copy of m/m coat color traits.

138 t role of introgression in generating winter coat color variation by repeatedly recruiting the regula

139 be the molecular changes underlying adaptive coat color variation in a natural population of rock poc

140 ciated with cursoriality, hypercanivory, and coat color variation in African wild dogs.

141 iously linked to introgression-driven winter coat color variation in the snowshoe hare (Lepus america

142 The ep mice have a coat color very similar to the black-colored parental st

143 Offspring coat color was concomitantly shifted toward pseudoagouti

144 As expected, average A(vy)/a coat color was darker in the supplemented group (P<0.01)

145 s segregating for black, yellow, and brindle coat colors, we demonstrate that pigment type switching

146 nly the ability of agouti to induce a yellow coat color when expressed in the skin of the lethal yell

147 Agouti gene is responsible for the wild-type coat color where hairs are banded black and yellow.

148 ivided into three major groups based on seed coat color: yellow (colorless), bicolored (saddle), and