ライフサイエンスコーパス: cockroach

1 la (AME), the circadian clock of the Madeira cockroach.

2 via inducing JH biosynthesis in the American cockroach.

3 ally in group-living insects like the German cockroach.

4 IgE levels, and skin prick test responses to cockroach.

5 ed in multiple brain circuits of the Madeira cockroach.

6 he US population is sensitized to the German cockroach.

7 rapamycin-treated (TORC1- and JH-deficient) cockroaches.

8 mide plays a role in the circadian system of cockroaches.

9 ntrol feces over the fecal extract of axenic cockroaches.

10 nonspecific transport of lipid molecules in cockroaches.

11 s of certain insects, such as honey bees and cockroaches.

12 ptera orders, with termites placed as social cockroaches.

13 humans and horses, but not with that used by cockroaches.

14 ization changes with speed in freely running cockroaches.

15 type, with significant differences within WT cockroaches.

16 -offs for a relatively understudied Tribe of cockroaches.

17 ributed in intestinal tracts of termites and cockroaches.

18 In some insects (e.g., moths and cockroaches), a few glomeruli are sexually dimorphic and

19 st management is the recommended approach to cockroach abatement; however, it is costly and difficult

20 DM) Dermatophagoides farinae, the Australian cockroach (ACR) Periplaneta australasiae and in the veno

21 In this study, we report that, during cockroach Ag-induced allergic airway inflammation, Foxp3

22 report that, in the absence of Abr function, cockroach allergen (CRA)-immunized mice experienced a fa

23 ed a defect in CCR6-/- mice in response to a cockroach allergen airway challenge characterized by dec

24 We sought to document immune responses to cockroach allergen and provide direction for the develop

25 Bla g 2 is a major indoor cockroach allergen associated with the development of as

26 n, 5 weeks postinfection, or after a chronic cockroach allergen asthma model.

27 Here we review the current understanding of cockroach allergen biology and the demographics associat

28 The cockroach allergen Bla g 1 forms a novel fold consisting

29 The cockroach allergen Bla g 1 has multiple repeats of appro

30 Primary German cockroach allergen Bla g 1 is detected in 63% of homes a

31 tructure of a 1:1 complex between the German cockroach allergen Bla g 2 and the Fab' fragment of a mo

32 C3, that binds to the C-terminal lobe of the cockroach allergen Bla g 2 has been solved at 1.8 A reso

33 ng of N-linked glycans from natural purified cockroach allergen Bla g 2 was accomplished by MALDI-MS.

34 successful and failed attempts to lessen the cockroach allergen burden in homes.

35 The administration of cockroach allergen by means of SCIT is immunologically m

36 We sought to perform a cockroach allergen component analysis to determine the a

37 New practice parameters for cockroach allergen control were presented.

38 two homologues of the Periplaneta americana cockroach allergen Cr-PI/Per a 3 in ACR and two isoforms

39 TGF-beta1 signaling activation in airways in cockroach allergen extract (CRE)-induced mouse models.

40 erize the trypsin-like proteinases in German cockroach allergen extracts used for clinical skin tests

41 sible for the proteolytic activity of German cockroach allergen have not been characterized.

42 ronmental variables (endotoxin; dog, cat and cockroach allergen in house dust) or variables that diff

43 Sensitivity to cockroach allergen is highly correlated with the develop

44 ilot studies suggest that immunotherapy with cockroach allergen is more likely to be effective with S

45 sought to test the hypotheses that domestic cockroach allergen measured prenatally would predict coc

46 ned A(2B) R expression by myeloid cells in a cockroach allergen model of murine asthma-like pulmonary

47 Prenatal exposure to cockroach allergen was associated with a greater risk of

48 Following exposure to cockroach allergen, alpha-1,3-glucan-specific IgA-secret

49 models of allergic asthma using ovalbumin or cockroach allergen, mice were treated with anti-RGMb or

50 Despite having cross-reactivity with cockroach allergen, we observed that non-cross-reactive

51 nce supporting the existence of a functional cockroach allergen-CD206 axis in human fibrocytes, sugge

52 In cockroach allergen-induced airway responses, both intrap

53 basis for studying the mechanisms regarding cockroach allergen-induced allergic sensitization and as

54 ill discuss the epidemiological evidence for cockroach allergen-induced asthma, cockroach allergens,

55 ockroach allergens, the mechanisms regarding cockroach allergen-induced innate immune responses, and

56 ted house dust protects against ovalbumin or cockroach allergen-mediated airway pathology.

57 In cockroach allergen-sensitized mice, ethanol triggered as

58 1,3-glucan binds an Enterobacter species and cockroach allergen.

59 comes and mouse allergen were independent of cockroach allergen.

60 ly associated with poor asthma outcomes than cockroach allergen.

61 pregulated on dendritic cells in response to cockroach allergen.

62 meters of two groups of mice sensitized with cockroach allergen.

63 re associated with lower risk of asthma (for cockroach allergen: odds ratio per interquartile range i

64 ced by a house dust extract (HDE) containing cockroach allergens and endotoxin.

65 IgE antibody levels to cockroach allergens and extract, but not IgG or IgG(4) a

66 ith high morbidity and healthcare costs, and cockroach allergens are an established cause of urban pe

67 medial sanitation, large-scale reductions in cockroach allergens below clinically relevant thresholds

68 Although successful removal of cockroach allergens from the infested environment has be

69 Cockroach allergens identification and their expression

70 Sensitization to cockroach allergens is a major risk factor for asthma.

71 Outbred mice were exposed to cockroach allergens on Days 0 and 14; and on Day 21, mic

72 Component analysis of 8 cockroach allergens revealed significant differences in

73 ested to be important for the penetration of cockroach allergens through epithelial cells to mediate

74 The binding activity of cockroach allergens to CD206 was determined by solid-pha

75 and IgG(4)) levels to total cockroach and 8 cockroach allergens were determined in 2 groups of cockr

76 to investigate the functional interaction of cockroach allergens with CD206 in fibrocytes.

77 Specifically, recognition of more cockroach allergens with higher allergen-specific IgE le

78 community with high levels of both mouse and cockroach allergens, mouse allergen appears to be more s

79 dence for cockroach allergen-induced asthma, cockroach allergens, the mechanisms regarding cockroach

80 regulation, and developmental expression of cockroach allergens, thus providing insight into their f

81 nd endotoxin, house dust mite, cat, dog, and cockroach allergens.

82 Preincubation of sera from cockroach-allergic subjects with WbGST partially deplete

83 ortant information relevant to understanding cockroach allergies and their treatment.

84 jor targets of IgE responses associated with cockroach allergies.

85 Cockroach allergy is a key contributor to asthma morbidi

86 -glucan results in suppressed development of cockroach allergy via pulmonary alpha-1,3-glucan-specifi

87 eonates and were no longer protected against cockroach allergy.

88 ion for the development of immunotherapy for cockroach allergy.

89 ing Enterobacter (MK7) are protected against cockroach allergy.

90 ibody (IgE, IgG, and IgG(4)) levels to total cockroach and 8 cockroach allergens were determined in 2

91 ficantly higher odds of sensitization to the cockroach and cat allergens compared to those without gl

92 Sera from patients allergic to cockroach and mite were tested for IgE reactivity to the

93 r sensitization to inhaled allergens such as cockroach and moth using ImmunoCAP.

94 tized to common inhaled allergens, including cockroach and moth.

95 Cockroach and mouse allergens have both been implicated

96 urban neighborhoods, pest allergens, such as cockroach and mouse, are present in high concentrations

97 o related polyneopteran species, the Madeira cockroach and the desert locust.

98 icide resistance intervention strategies for cockroaches and evaluated resistance evolution across mu

99 mmunoreactive organization in honey bees and cockroaches and the suggested roles of octopamine in sen

100 nor allergens Der p 10 (dust mite), Bla g 7 (cockroach), and Ani s 3 (fish parasite)-in terms of IgE

101 s (house cricket) and Periplaneta americana (cockroach), and re-examined its role in Drosophila melan

102 inhalant allergens from house dust mites and cockroaches, and lipocalins.

103 ng airborne viruses, smoke, indoor dampness, cockroaches, and poor access to health care.

104 as both a phagostimulant and deterrent in GA cockroaches, and this newly acquired peripheral taste se

105 ethnicity; participant age; dog(s), cat(s), cockroaches, and/or smoker(s) in the home; and carpeted

106 e promoted allergic sensitization to inhaled cockroach antigen in the absence but not the presence of

107 n sensitized and chronically challenged with cockroach antigen to induce chronic airway disease.

108 season, maternal atopy, education, race, and cockroach antigen.

109 ments infected mice were exposed to low-dose cockroach antigen.

110 duced similar responses after challenge with cockroach antigen.

111 Cockroaches are a group of insects that evolved early in

112 The fat bodies of most cockroaches are inhabited by Blattabacterium, which are

113 y responses to fungi-, house dust mite-, and cockroach-associated allergens in mouse models.

114 were sensitized to house dust mite (HDM) or cockroach at day 0, treated with IL-6R inhibitors at day

115 s were found between overcrowding, molds and cockroaches at home, and atopic multiple-trigger wheeze

116 ed for mouse (Mus m 1), dust mite (Der p 1), cockroach (Bla g 1), and mold (Alternaria mix) allergens

117 major glutathione-S transferase allergen of cockroach (Bla g 5) and the glutathione-S transferase of

118 The allergenicity of several German cockroach (Bla-g) antigens at the level of IgE responses

119 tics of sprawled posture insects such as the cockroach Blaberus discoidalis.

120 servations of kinematics and dynamics of the cockroach Blaberus discoidalis; in particular, motoneuro

121 sfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule

122 om central-complex neurons in freely walking cockroaches (Blaberus discoidalis), we identified classe

123 rection coding in the central complex of the cockroach, Blaberus discoidalis.

124 -gated sodium channel BgNaV1 from the German cockroach Blattella germanica by shifting the threshold

125 The German cockroach (Blattella germanica L.) is a worldwide pest t

126 ble trait that evolved in a number of German cockroach (Blattella germanica L.) populations in respon

127 We provisioned nymphs from three German cockroach (Blattella germanica L.) populations, which di

128 Allergy to the German cockroach (Blattella germanica) is a significant asthma

129 lar experimental manipulations of the German cockroach (Blattella germanica), carpenter ant (Camponot

130 Aggregation of the German cockroach, Blattella germanica, is regulated by fecal ag

131 distribution of MIP-related peptides in the cockroach brain.

132 mparable with high-performing organisms like cockroaches but suffer significant performance loss on f

133 ied IgE directed against house dust mite and cockroach, but not against timothy grass, the latter wit

134 Indoor aeroallergens, including rat, mouse, cockroach, cat, dog, and dust mites, measured in dust sa

135 tropicalis, cat, German cockroach, Oriental cockroach, codfish, crab, shrimp, and cheese (all P </=

136 e unconditioned stimulus of saline solution, cockroaches conditioned in the early subjective night sh

137 ng the largest and most abundant of the wood cockroaches, constituting >50% of the biomass of the woo

138 g insect allergens from house dust mites and cockroaches contribute to allergic inflammatory diseases

139 resistance has been a consistent barrier to cockroach control since the 1950s.

140 al biology and their relationship to current cockroach control strategies.

141 ects of venom that wasps use in preying upon cockroaches could provide insights into this problem.

142 rial testing the use of insecticidal bait on cockroach counts and asthma morbidity.

143 evices to enter a vertically confined space, cockroaches crawled at velocities approaching 60 cms(-1)

144 n this field have been performed in locusts, cockroaches, crickets, and stick insects, the examples w

145 disease in invertebrates, including shrimp, cockroaches, crickets, moths, crayfish, and sea stars.

146 s from a gut transcriptome of a wood-feeding cockroach, Cryptocercus punctulatus, were selected as th

147 In both wild-type and glucose-averse (GA) cockroaches, D-fructose and D-glucose stimulated sugar-g

148 In contrast, in GA cockroaches, D-glucose also stimulated bitter-GRNs and s

149 The antennae of adult male German cockroaches detect a contact sex pheromone embedded in t

150 hat act as fecal aggregation agents and that cockroaches discriminate among the complex odors that em

151 rdless of specific sensitization) dust mite, cockroach, dog, and dampness-related agents.

152 n testing was performed for Alternaria, cat, cockroach, dog, Dermatophagoides farinae (Der F), Short

153 were measured for Alternaria alternata, cat, cockroach, dog, Dermatophagoides farinae, short ragweed,

154 f common aeroallergens including Alternaria, cockroach, dog, dust mite, cat, mouse, and rat allergens

155 s of these neurons have now been recorded in cockroaches during walking.

156 months of age were analyzed for total, anti-cockroach, dust mite, and mouse IgE.

157 hat characterizes olfactory communication in cockroaches: Each long-range sex pheromone identified to

158 d is widely available, resulted in sustained cockroach elimination over 12 months and was associated

159 by the mandibular glands, as occurs in early cockroach embryos.

160 ediated by PaNav1 channels from the American cockroach even though their domain II paddle motifs are

161 Cockroach exoskeletons provided biological inspiration f

162 ations for allergic disease, and standardize cockroach exposure assays.

163 e intervention, insecticidal bait, to reduce cockroach exposure in the home of children with asthma i

164 Cockroach exposure is a major risk factor for the develo

165 The impact of reducing cockroach exposure on asthma outcomes is not known.

166 AND We developed and used a 12 week model of cockroach extract (CE)-mediated AHR, airway inflammation

167 tized and challenged with ovalbumin (OVA) or cockroach extract (CE).

168 virus of mice [PVM]) and exposed to low-dose cockroach extract (CRE) in early and later life, and air

169 were exposed to pneumonia virus of mice and cockroach extract in early and later life and then chall

170 Biting flies, cockroaches, filth flies, and triatomid bugs represent a

171 ric acids were associated with nBla g 1 from cockroach frass.

172 offspring-viability assumption in Tanzanian cockroaches, fruit flies, pipefish, wild mallards, and f

173 an area in which (1) the climate discourages cockroach, fungal, and mite growth and (2) dander allerg

174 In this study we asked whether German cockroach (GC) feces (frass) could initiate an innate im

175 We recently identified that German cockroach (GC) frass contains a TLR2 ligand allowing us

176 German cockroach (GCr) allergen extracts are complex and hetero

177 tic behaviour between two species of hissing cockroaches, Gromphadorhina oblongonota and Aeluropoda i

178 Cockroaches harbor the obligate flavobacterial endosymbi

179 A new study of the escape behavior of the cockroach has found that its spatial variability is base

180 lt of toxic baits, populations of the German cockroach have rapidly evolved an adaptive behavioral av

181 For nearly a half century, cockroaches have been recognized as a major cause of ast

182 glucose-containing bait, glucose-averse (GA) cockroaches have lower performance than wild-type (WT) c

183 of Burkholderia-infected Madagascar hissing cockroaches (HCs) increases their survival.

184 previously unknown pheromonal structure for cockroaches, highlighting the great chemical diversity t

185 ed that A. compressa larvae impregnate their cockroach hosts from inside with large amounts of an ora

186 ounter during their development inside their cockroach hosts.

187 t (AI) treatments can successfully eliminate cockroaches if starting resistance levels are low.

188 n the sum of allergen-specific IgE and total cockroach IgE levels (r = 0.86, P < .001).

189 lted in significant changes from baseline in cockroach IgE, IgG4, and blocking antibody levels.

190 The safety profile of cockroach immunotherapy was reassuring in all studies.

191 t of allergen-specific IgE to dust mites and cockroach in plasma.

192 son of birth, PM2.5, breastfeeding, mold and cockroaches in home, and distance from highway.

193 s have lower performance than wild-type (WT) cockroaches in several fitness-determining traits.

194 Wood cockroaches in the genus Parcoblatta, comprising 12 spec

195 ere we find that extracts from dust mite and cockroach induce sustained Ca(2+) elevations in AECs thr

196 Both HDM and cockroach induced a type 2/type 17 cytokine profile and

197 sed IL-6 expression in the airways, but only cockroach induced sIL-6R expression.

198 In contrast, cockroach-induced inflammation involved activation of IL

199 a T-cell deficiency significantly attenuated cockroach-induced inflammation.

200 This cockroach is a major cause of allergic disease and serve

201 Cockroach is one of the most important sources of indoor

202 Sensitization to cockroach is one of the strongest identified risk factor

203 Exposure to cockroaches is an important asthma trigger, particularly

204 The compound eye of cockroaches is obligatory for entrainment of the Madeira

205 mite, orchard grass, ragweed, wormwood, dog, cockroach, Japan cedar).

206 Isolated cockroach legs also had gravity-independent rest positio

207 We show here that the ability of the cockroach Leucophaea maderae to acquire olfactory memori

208 the distribution of MIPs in the brain of the cockroach Leucophaea maderae.

209 Cockroach, like other allergens, contains trypsin-like e

210 to that studied in other orthopteroid taxa (cockroaches, locusts, crickets, tettigoniids).

211 ssociation with asthma, and sensitization to cockroach mediated 13% to 20% of the association with fo

212 Higher house dust concentrations of cockroach, mouse, and cat allergens in the first 3 years

213 In contrast, first-year exposure to cockroach, mouse, and cat allergens was negatively assoc

214 Exposure to certain allergens (cockroach, mouse, dust mite) was significantly associate

215 We show that in the cockroach mushroom bodies there are two types of plastic

216 lta-HXTX-Ar1a also inhibited inactivation of cockroach Na(V) channels and was insecticidal to sheep b

217 ation of ovarian apoptosis in females of the cockroach Nauphoeta cinerea, an insect with reproductive

218 Feces from axenic cockroaches (no microorganisms in the alimentary tract)

219 ria alternata, egg, peanut, milk, and German cockroach) obtained from 594 children at age 2 years.

220 ns between IgE subtypes and glaucoma for the cockroach (odds ratio [OR] = 2.78; 95% CI = 1.34, 5.76),

221 ith at least one neuropil not present in the cockroach or locust.

222 B, the presence of IgE responses specific to cockroach or moth by ImmunoCAP were found in 27.8% or 52

223 oides farina, Blomia tropicalis, cat, German cockroach, Oriental cockroach, codfish, crab, shrimp, an

224 of C. clypeatus and the mushroom body of the cockroach P. americana reveal in both a layered motif pr

225 n to mites (P < 0.001), animals (P = 0.001), cockroaches (P < 0.001), and foods (P = 0.042), and furt

226 The broad wood cockroach, Parcoblatta lata, is among the largest and mo

227 oteinase previously cloned from the American cockroach (Per a 10).

228 red whole-cell patch-clamp recordings in the cockroach Periplaneta americana to characterize synaptic

229 sp larvae develop on and inside the American cockroach Periplaneta americana, a host that can harbor

230 In the antennal lobe of the cockroach Periplaneta americana, gamma-aminobutyric acid

231 ion with the mushroom body of an insect, the cockroach Periplaneta americana.

232 al unpaired median neurons from the American cockroach Periplaneta americana.

233 ct, we repeated some of these experiments in cockroach (Periplaneta americana) and mouse.

234 neurons was also identified in the American cockroach (Periplaneta americana) and the pink winged st

235 arcodes in a global urban pest, the American cockroach (Periplaneta americana).

236 of vitellogenesis regulation in the American cockroach, Periplaneta americana Our data showed that a

237 The cockroach, Periplaneta americana represents a basal inse

238 ennal grooming was prevented in the American cockroach, Periplaneta americana, field emission gun sca

239 ch suggest that it may provide a new tool in cockroach population detection, monitoring, and control.

240 hile insecticides are essential for reducing cockroach populations and improving health outcomes, ins

241 ynthesized, could be deployed for monitoring cockroach populations.

242 ecently been realized through suppression of cockroach populations.

243 sistant and susceptible house fly and German cockroach populations.

244 Several cockroach-produced allergens have been identified and ch

245 Cockroaches rapidly traversed crevices in 300-800 ms by

246 in New Orleans and to examine the impact of cockroach reduction on asthma outcomes.

247 rasshopper, and 13.2 ug/100 g dry weight for cockroach, representing the first validated report on th

248 Using the cockroach retrocerebral complex, the presented protocol

249 The circadian pacemaker of the Madeira cockroach, Rhyparobia (Leucophaea) maderae, is located i

250 es of human running, a horse trotting, and a cockroach running.

251 is obligatory for entrainment of the Madeira cockroach's circadian clock, but the cellular nature of

252 onclusion, IgE sensitization to mites, pets, cockroaches, seafood, and cheese, respectively, is signi

253 ntestinal communities in the closely related cockroaches seem to be shaped primarily by the selective

254 Cockroach sensitization (C+) might be a proxy for microb

255 Several genes have been associated with cockroach sensitization and asthma-related phenotypes.

256 Bla g 2 in prenatal kitchen dust predicted cockroach sensitization at the ages of 5 to 7 years (adj

257 h allergen measured prenatally would predict cockroach sensitization in early childhood and that this

258 Cockroach sensitization is an important risk factor for

259 immune responses, and the genetic basis for cockroach sensitization.

260 ant role in conferring the susceptibility to cockroach sensitization.

261 Cockroach sensitization/exposure was only associated wit

262 were mouse sensitized/exposed, and 41% were cockroach sensitized/exposed based on bedroom floor expo

263 ach allergens were determined in 2 groups of cockroach-sensitized 10-year-old children with (n = 19)

264 Asthmatic and nonasthmatic cockroach-sensitized individuals exhibit similar TH 2-po

265 milis), grasshopper (Locusta migratoria) and cockroach (Shelfordella lateralis), using an ultra-high

266 wo odors (peppermint and vanilla), untrained cockroaches showed a clear preference for vanilla at all

267 randomized, double-blind biomarker study of cockroach SLIT versus placebo in adults; (3) a randomize

268 , double-blind biomarker study of 2 doses of cockroach SLIT versus placebo in children; and (4) an op

269 e octapeptide segment IFGSFFTL in IIIS6 of a cockroach sodium channel BgNa(V), besides Ser_3i15 and L

270 urrents and antagonizes the action of BTX on cockroach sodium channels, suggesting that it also binds

271 IVS6, are all critical for BTG 502 action on cockroach sodium channels.

272 s utility in monitoring several endemic wood cockroach species in red-cockaded woodpecker habitats.

273 ecological range and global distribution of cockroach species.

274 o (aOR) 2.08 (1.38, 3.15)]; M. perstans with cockroach-specific IgE [aGMR 2.37 (1.39, 4.06)], A. lumb

275 s) found a significantly greater increase in cockroach-specific IgE levels between the active and pla

276 roups 1, 2, 4, 5, 6, 7, 9, and 11, and total cockroach-specific IgE levels were measured with the i6

277 a health across a range of outcomes, whereas cockroach-specific IgE levels were not.

278 PT; median Dermatophagoides-specific IgE and cockroach-specific IgE were 1440 and 220 ng/ml, respecti

279 .92; P < .0001) and a trend toward increased cockroach-specific IgG4 levels in actively treated subje

280 Our sampling effort generated 284 cockroach specimens, most from New York City, plus 15 ad

281 an open-label safety and biomarker study of cockroach subcutaneous immunotherapy (SCIT) in adults.

282 an open-label study to assess the safety of cockroach sublingual immunotherapy (SLIT) in adults and

283 of the locust than the more closely related cockroach suggesting that the sensory ecology plays a st

284 , intervention homes had significantly fewer cockroaches than did control homes (mean change in cockr

285 different serine proteinases from the German cockroach that may, via PAR2 activation, play different

286 association with Blattabacterium has allowed cockroaches to subsist successfully on nitrogen-poor die

287 Exoskeletal strength allowed cockroaches to withstand forces 300 times body weight wh

288 aches than did control homes (mean change in cockroaches trapped, 13.14; 95% CI, 6.88-19.39; P < .01)

289 Within the Madagascan giant hissing cockroaches (Tribe Gromphadorhini) differences in morpho

290 Cockroaches, unlike most terrestrial insects, excrete wa

291 Dc1a promotes opening of German cockroach voltage-gated sodium (Nav) channels (BgNav1),

292 performed tetrode recordings from the CC of cockroaches walking in place on a slippery surface.

293 ugh sensitization/exposure to both mouse and cockroach was generally associated with worse asthma, mo

294 ribe a food-hygienic strategy of the emerald cockroach wasp Ampulex compressa.

295 mide plays a role in the circadian system of cockroaches, we studied SIFamide in Rhyparobia (= Leucop

296 within heterogeneous populations, WT German cockroaches will over time prevail in abundance over GA

297 We challenged cockroaches with horizontal crevices smaller than a quar

298 Inoculation of axenic cockroaches with individual bacterial taxa significantly

299 adults of both sexes, and "contamination" of cockroaches with the cuticular lipids of another stage o

300 All cockroaches, with the exception of one cave-dwelling gen