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1 letion of chromosome arms 1p and 19q (1p/19q codeletion).
2 tors (age, sex, grade, IDH mutations, 1p/19q codeletion).
3 eletion is further potentiated by Hif-1alpha codeletion.
4 utated in oligodendroglial tumors with 1p19q codeletion.
5 testine damage, which was not rescued by p53 codeletion.
6 ined to predict IDH mutations and the 1p/19q codeletion.
7 outine practice for prediction of the 1p/19q codeletion.
8 R 0.79; 95% CI, 0.61 to 1.03; P = .08), with codeletion 7.3 years, 25.0%, and 14.9% versus 13.2 years
9 95% CI, 0.63 to 0.98; P = .033), with 1p19q codeletion 9.3 years, 26.2%, and 13.6% versus 14.2 years
10 ce in oncogenesis, SCD underwent monoallelic codeletion along with PTEN on chromosome 10q in approxim
12 ic remodeling from such coamplifications and codeletions and delineate genes driving cancer metabolis
14 letion of chromosome arms 1p and 19q (1p/19q codeletion) and mutations in the metabolic genes isocitr
15 (IDH1/2 wt, IDH1/2 mut, and IDH1/2 mut 1p19q codeletion) and the four subtypes of GBMs (classical, me
16 and the long arm of chromosome 19, or 1p19q codeletion; and (c) methylguanine methyltransferase prom
17 Finally, 9p arm-level loss and JAK2-PD-L1 codeletion (at 9p24) were predictive markers of poor sur
18 nsitivity and specificity of PRESS to detect codeletion by means of cystathionine quantification were
19 ade gliomas with IDH mutations and no 1p/19q codeletion had mutations in TP53 (94%) and ATRX inactiva
20 rade gliomas with an IDH mutation and 1p/19q codeletion had the most favorable clinical outcomes.
21 letion of chromosome arms 1p and 19q (1p/19q codeletion) have been implicated as clinically relevant
23 cated at chromosome 13q14 - was common, deep codeletion infrequent, and gene loss associated with low
25 2A)/methylthioadenosine phosphorylase (MTAP) codeletion occurs frequently in non-small cell lung canc
26 and predictive marker in glioblastoma; (ii) codeletion of 1p and 19q differentiating oligodendroglio
31 rs sustained either deletion of p16 alone or codeletion of both p16 and p15 or amplification of CDK4.
34 in the TERT promoter, mutations in IDH, and codeletion of chromosome arms 1p and 19q (1p/19q codelet
36 ies of these cell lines for the incidence of codeletion of genes located near p16, in particular, the
38 cumulation within this developmental window, codeletion of H3f3a and H3f3b does not lead to immediate
41 e p16, p15 or CDK4 genes, whereas homozygous codeletion of p16 and p15 was observed in both primary a
47 However, heterozygous deletion of Sav1 or codeletion of Rassf1a and Sav1 produced liver tumors wit
48 ion during olaparib treatment.RESULTSShallow codeletion of RNASEH2B and adjacent RB1 - colocated at c
51 e severity of this defect was exacerbated by codeletion of the Gcn5 acetyltransferase within SAGA.
52 pha,-beta gene cluster; one cell line bore a codeletion of the IFNA1 gene but retained the IFNB1 locu
56 sis to promote erythroid development because codeletion of the proapoptotic effectors Bax and Bak can
57 way, because the cell death was rescued with codeletion of the proapoptotic proteins Bax and Bak.
65 aplastic oligodendroglial tumors with 1p/19q codeletion, probable 20-year overall survival following
66 ic intraepithelial neoplasia, and, with Pten codeletion, resulted in rapid progression to castration-
67 iomas with strong EGFR expression and 1p/19q codeletion showed reduced survival, compared with their
68 ty hospitals based on availability of 1p/19q codeletion status and a PRESS acquisition optimized for
69 ding to locally determined chromosome 1p/19q codeletion status and baseline tumour size) to oral vora
70 ix (66.7%) of these nine gliomas, the 1p/19q codeletion status as determined with CMA disagreed with
71 Health Organization grade II/III) and 1p/19q codeletion status determined with FISH that were accrued
72 with IDH-mutant high-risk LGG regardless of codeletion status receive benefit from the addition of P
74 entify diffuse gliomas misassigned to 1p/19q codeletion status with fluorescence in situ hybridizatio
75 for AOA (3 v 4); and modified grade, 1p/19q codeletion status, and oligodendroglial histology for th
77 ssion with L2 regularization) and the 1p/19q codeletion (support vector machine with radial basis fun
78 lassified into 2 molecular subgroups: 1p/19q codeletion/TERT-promoter mutations or inactivating mutat
79 ation (FISH) is a standard method for 1p/19q codeletion testing in diffuse gliomas but occasionally r
80 re the most useful for predicting the 1p/19q codeletion (up to 14.5% of importance for the small-zone
81 OS, 8.2 vs. 2.5 years), both p < 0.01.1p/19q codeletion was associated with prolonged PFS (7.7 vs. 1.
82 dehydrogenase (IDH) mutations and the 1p/19q codeletion, which the World Health Organization classifi
83 ood mononuclear cells from patients with SS, codeletion with CDKN2A occurred in 18% of samples but lo