ライフサイエンスコーパス: coelenterazine

1 a similar structure to the native substrate coelenterazine.

2 escence following systemic administration of coelenterazine.

3 tive decarboxylation of the bound substrate, coelenterazine.

4 lungs of living mice tail-vein injected with coelenterazine.

5 its proper substrate is the frequently used coelenterazine.

6 protein and the core of the natural product coelenterazine.

7 bic core cavity that accommodates the ligand coelenterazine-2-hydroperoxide.

8 n bond donor-acceptor separations around the coelenterazine-2-hydroperoxy substrate, initiated by sma

9 protein that utilizes its natural substrate coelenterazine, a benefit of which is demonstrated at va

10 asis for this effect were also explored with coelenterazine, a Pgp substrate.

11 We found that mixing coelenterazine-a eukaryote-specific luciferin-with Pyros

12 e-induced tonic-clonic seizures upon in vivo coelenterazine administration, without affecting higher

13 bioluminescence and for the extensive use of coelenterazine among marine organisms.

14 of red-shifted luciferins based on synthetic coelenterazine analogs and corresponding mutants of Nano

15 Eleven new coelenterazine analogs containing the 3,7-dihydroimidazo

16 aired two aequorin conjugates with different coelenterazine analogues and then resolved the two signa

17 Interestingly, coelenterazine analogues share structural and physiochem

18 quorea victoria is unable to produce its own coelenterazine and is dependent on a dietary supply of t

19 Therefore, using coelenterazine and noninvasive bioluminescence imaging i

20 pecific antibody followed by the addition of coelenterazine and signal acquisition using a luminomete

21 wever, DLR substrates (e.g., d-luciferin and coelenterazine) are expensive and not stable enough to d

22 rotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considera

23 The molecule also contains coelenterazine as its chromophoric ligand.

24 properties and applications of d-luciferin, coelenterazine, bacterial, Cypridina and dinoflagellate

25 analysis of the hydrogen bond network in the coelenterazine binding cavity, it is proposed that the t

26 f enzyme and vascular systems indicated that coelenterazine chemiluminescence is a sensitive marker f

27 scular O(2)( *-) production, as indicated by coelenterazine chemiluminescence, were significantly inc

28 , we designed a novel anionic phosphonylated coelenterazine, CLZ-2P, as the nanoluciferase substrate.

29 n using light or by the luciferase substrate coelenterazine (CTZ).

30 eins catalyses the production of light using coelenterazine disulfate and ATP.

31 nescent reaction using ATP and the substrate coelenterazine disulfate.

32 L) does not serve as a substrate for RL, and coelenterazine does not serve as a substrate for FL eith

33 Also the H-bonding between His-22 and the coelenterazine found in the active photoprotein is prese

34 unable to produce light unless provided with coelenterazine from an external source.

35 In contrast, the chemiluminescent probe coelenterazine had no significant effect on xanthine oxi

36 zyme/protein (RL) by injecting the substrate coelenterazine in living mice.

37 e catalyzes the degradation of its substrate coelenterazine in the presence of molecular oxygen, resu

38 fter intratumoral injection as determined by coelenterazine injection followed by imaging.

39 Coelenterazine is widely distributed among marine organi

40 ovel luciferase (PyroLuc) and, combined with coelenterazine, it produced light.

41 Although coelenterazine itself does not enter cells because of Pg

42 (within 2-4 min) upon re-addition of Ca++ to coelenterazine-loaded cells, a finding consistent with v

43 In addition to the native coelenterazine luciferase substrate, we used the synthet

44 transfected with a codon-humanized Rluc show coelenterazine-mediated bioluminescence in a highly MDR1

45 Tyr-138 hydrogen bonded to the coelenterazine N1-atom in unreacted obelin is moved away

46 injection of rGluc followed by its substrate coelenterazine, non-invasive visualization of tumor vasc

47 in the absence of calcium by incubation with coelenterazine, oxygen and a thiol agent.

48 animals, wherein Pgp-mediated alterations in coelenterazine permeability may impact results.

49 Stimulated by coelenterazine, pHIL experiences bioluminescence resonan

50 The noninvasive repeated coelenterazine stimulation of transplanted cells is feas

51 Upon the addition of the substrate coelenterazine, the energy produced by Luc8 was nonradia

52 es are exposed to the luciferase's substrate coelenterazine, the energy released by substrate catabol

53 uorin, light is produced by the oxidation of coelenterazine, the luciferin used by at least seven mar

54 m the 2-hydroperoxy group of the chromophore coelenterazine to bulk solvent.

55 o catalyze the oxidation of the chromophore, coelenterazine, to coelenteramide with the release of li

56 duction, little is known about mechanisms of coelenterazine transport and cell permeation.

57 he majority of chemiluminescence produced by coelenterazine treatment of ERaeq-expressing 293 cells w

58 ity becomes important, especially for marine coelenterazine-type luciferins with limited solubility.

59 scence, where the lower the concentration of coelenterazine under the oxidation of superoxide anion,

60 n, and following addition of the chromophore coelenterazine underwent Ca(++)-activated chemiluminesce

61 herein present the first structures for any coelenterazine-using luciferase.

62 substrate, we used the synthetic derivative coelenterazine-v, which further red-shifts the emission

63 erase-luciferin and Rluc: Renilla luciferase-coelenterazine), we tested the efficacy of TRAIL using r

64 intranasally delivered luciferase substrate coelenterazine, we show enhanced regenerative properties

65 s been no evidence to indicate the origin of coelenterazine within the phylum Cnidaria.