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1 tween complex II and complex III, presumably coenzyme Q.
2 tion of several substrates, such as heme and coenzyme Q.
3  oxidizes H(2)S while concomitantly reducing coenzyme Q.
4 and transferring the energy to mitochondrial coenzyme Q.
5  electron transport, including Vitamin K and Coenzyme Q.
6  which was accompanied by a lower content of coenzyme Q.
7 es electrons from acyl-CoA dehydrogenases to coenzyme Q.
8 diate, as well as the final product (13)C(6)-coenzyme Q.
9                                              Coenzyme Q(0) (Q(0)), a strong electrophile, is toxic to
10         The purified enzyme had also an NADH-coenzyme Q(0) reductase (NADH: external acceptor (quinon
11 ADH-ferricyanide reductase activity and NADH-coenzyme Q(0) reductase activity of plasma membranes and
12      The enzyme was not NAD(P)(+) dependent; coenzyme Q(0) was the preferred electron acceptor.
13           K(M) values for dihydroorotate and coenzyme Q(0) were similar to wild type.
14                                              Coenzyme Q(1)(0) (1-10 nM), which has been reported to f
15                                              Coenzyme Q(1)(0) (CoQ(1)(0); also called ubiquinone) is
16                             In mitochondria, coenzymes Q(1) and Q(2) did not bond to the 50-kDa prote
17                               The effects of coenzyme Q(10) (CoQ(10)) and alpha-tocopherol on the rat
18                                              Coenzyme Q(10) (CoQ(10)) is a naturally occurring compou
19                                              Coenzyme Q(10) (CoQ(10)) is a vital lipophilic molecule
20                                              Coenzyme Q(10) (CoQ(10)) is essential for electron trans
21 esponse-attenuating effects of vitamin E and coenzyme Q(10) (CoQ(10)) supplementation.
22                    Decreased brain levels of coenzyme Q(10) (CoQ(10)), an endogenously synthesized li
23 neficial effects of supplementing cells with coenzyme Q(10) (CoQ(10)).
24  functions as an oxidoreductase that reduces coenzyme Q(10) (CoQ) (also known as ubiquinone-10), whic
25 fying diseases displaying chronic low plasma Coenzyme Q(10) (CoQ) values may be important to prevent
26        Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, a
27 study demonstrates that delivery of oxidized Coenzyme Q(10) (ubidecarenone) to increase mitochondrial
28 chondrial antioxidants alpha-lipoic acid and coenzyme Q(10) also suppresses Bak expression in the coc
29 dismutase, catalase, glutathione peroxidase, coenzyme Q(10) and ORAC levels in diabetic rats.
30 r protein 1 to recycle the lipid antioxidant coenzyme Q(10) and suppress ferroptosis.
31                                   Defects of coenzyme Q(10) biosynthesis represent one of the few tre
32 wo of 16 candidate genes implicated in human coenzyme Q(10) biosynthesis.
33 ured skin fibroblasts from the patient had a coenzyme Q(10) biosynthetic rate of 11% of normal contro
34          We genotyped a patient with primary coenzyme Q(10) deficiency who presented with neonatal la
35                     In view of the rarity of coenzyme Q(10) deficiency, we hypothesized that the dise
36 c acid, a-tocopherol, all-trans-retinol, and coenzyme Q(10) in the tested samples was determined thro
37 id, alpha-tocopherol, all-trans-retinol, and coenzyme Q(10) in the tested samples was determined thro
38                                              Coenzyme Q(10) is a critical cofactor in the electron tr
39                                              Coenzyme Q(10) is a mobile lipophilic electron carrier l
40                                   Similarly, coenzyme Q(10) is also effective in animal models and ha
41 n and a consequent increase in the levels of coenzyme Q(10), an endogenous lipophilic antioxidant.
42 SP1 is mediated by ubiquinone (also known as coenzyme Q(10), CoQ(10)): the reduced form, ubiquinol, t
43 ial in animal models of PD include creatine, coenzyme Q(10), Ginkgo biloba, nicotinamide, and acetyl-
44          The method is also able to separate coenzyme Q(10).
45 toxicity was seen with the parent ubiquinone coenzyme Q(10.) Inhibition of cancer cell growth by Mito
46 tidepressants, anticonvulsants (topiramate), coenzyme Q-10, and L-carnitine.
47 n of complex I, complex II, complex III, and coenzyme Q [11-14].
48 he Caenorhabditis elegans clk-1 mutants lack coenzyme Q(9) and instead accumulate the biosynthetic in
49 s indicated that both codon reassignment and coenzyme Q(9) likely had single origins with multiple lo
50                   This pathway also produces coenzyme Q (a component of the respiratory chain), dolic
51 n to 4-hydroxybenzoic acid as a precursor of coenzyme Q, a redox lipid essential to the function of t
52 d that individuals with mutations in COQ6, a coenzyme Q (also called CoQ(10), CoQ, or ubiquinone) bio
53  by increasing concentrations of the reduced coenzyme Q analog decylubiquinol.
54 , alpha tocopherol, ebselen, or idebenone (a coenzyme Q analogue); or the MPT blockers, cyclosporin A
55 s of Complex III, cyanide, oligomycin A, and coenzyme Q analogues decreased 4HPR-induced hydroperoxid
56                                          The coenzyme Q analogues were very effective in this respect
57 bolism and recycling of antioxidants such as coenzyme Q and alpha-tocopherol.
58 nzyme Q but there was no interaction between coenzyme Q and the effect of rosuvastatin.
59  pet mutant C92 was found to be deficient in coenzyme Q and to have low mitochondrial NADH-cytochrome
60  reaction in the biosynthesis of ubiquinone (coenzyme Q) and menaquinone (vitamin K2), essential isop
61 sue concentrations of the essential cofactor coenzyme Q are decreased by statins, and this could be h
62  role, H(2)S transfers its reducing power to coenzyme Q as it is oxidized by sulfide quinone oxidored
63  was exhibited with both NAD(P)H and reduced coenzyme Q as substrate.
64 e of electron leakage is located proximal to coenzyme Q at the electron transfer flavoprotein that sh
65                                 Cytochrome b coenzyme Q binding site mutations were observed in 33% o
66 amino acid changes in one of the ubiquinone (coenzyme Q) binding sites (Qo).
67 est that the np 14459 mutation may alter the coenzyme Q-binding site of complex I.
68 ne that supports both complex I assembly and coenzyme Q biosynthesis and is disrupted in a previously
69  compensatory mechanisms, including enhanced coenzyme Q biosynthesis and the mitochondrial unfolded p
70 and enables autophosphorylation but inhibits coenzyme Q biosynthesis in vivo, demonstrating functiona
71 atter gene has been shown to be required for coenzyme Q biosynthesis in yeast and bacteria.
72  a nonfermentable carbon source and restored coenzyme Q biosynthesis, although at lower levels than t
73 ntrol of several metabolic processes such as coenzyme Q biosynthesis, assuring an appropriate energy
74 patient fibroblasts also exhibited defective coenzyme Q biosynthesis, substantiating a second functio
75 ns and helps connect a key oxidoreductase to coenzyme Q biosynthesis.
76 athway, which is necessary for mitochondrial coenzyme Q biosynthesis.
77  role in bacterial ubiquinone (also known as coenzyme Q) biosynthesis or microbial biodegradation of
78 s an important role in bacterial ubiquinone (coenzyme Q) biosynthesis.
79 rnesylated analogues of intermediates in the coenzyme Q biosynthetic pathway as substrates showed tha
80  Coq9p may either catalyze a reaction in the coenzyme Q biosynthetic pathway or have a regulatory rol
81 yme Q by the other proteins constituting the coenzyme Q biosynthetic pathway.
82      Here we present physical evidence for a coenzyme Q-biosynthetic polypeptide complex in isolated
83  product, the mitochondrial electron carrier coenzyme Q, both in cultured cancer cells and tumors.
84                         Rosuvastatin reduced coenzyme Q but there was no interaction between coenzyme
85                         Rosuvastatin reduced coenzyme Q, but even in patients with a low baseline coe
86  NDUF-2.1 to coordinate electron transfer to coenzyme Q by destabilizing the Q-binding pocket, causin
87 amination and ultimately its conversion into coenzyme Q by the other proteins constituting the coenzy
88                          Patients with lower coenzyme Q concentrations were older and had more advanc
89 y shuttling elections from NADH and FADH2 to coenzyme Q (CoQ) and cytochrome c.
90            Mutations affecting mitochondrial coenzyme Q (CoQ) biosynthesis lead to kidney failure due
91 d its human homolog ALDH3A1 to mitochondrial coenzyme Q (CoQ) biosynthesis, an essential pathway disr
92 t electron transfer chain defects, disrupted coenzyme Q (CoQ) biosynthesis, and metabolic rewiring.
93 d by defects in Complex III (CIII) activity, coenzyme Q (CoQ) biosynthesis, and mitochondrial calcium
94 mitochondrial matrix octapeptidase Oct1p and coenzyme Q (CoQ) biosynthesis-a pathway essential for mi
95 gene in Providencia stuartii is required for coenzyme Q (CoQ) biosynthesis.
96 member COQ8, whose function is essential for coenzyme Q (CoQ) biosynthesis.
97 n to knock down expression of enzymes in the Coenzyme Q (CoQ) biosynthetic pathway.
98 roton leak in Fmr1 KO mitochondria caused by coenzyme Q (CoQ) deficiency and an open cyclosporine-sen
99 t the relative amounts of the ubiquinones or coenzyme Q (CoQ) homologues, CoQ9 and CoQ10, are related
100 6.99.2] functions to maintain membrane-bound coenzyme Q (CoQ) in its reduced antioxidant state, there
101                                 Ubiquinol or coenzyme Q (CoQ) is a lipid-soluble electron carrier in
102                                              Coenzyme Q (CoQ) is a redox lipid that fulfills critical
103                                              Coenzyme Q (CoQ) is a redox-active lipid essential for c
104                                              Coenzyme Q (CoQ) is a redox-active lipid molecule that a
105                                              Coenzyme Q (CoQ) is a remarkably hydrophobic, redox-acti
106                                              Coenzyme Q (CoQ) is an electron transporter in the mitoc
107                                              Coenzyme Q (CoQ) is an essential lipid of cells present
108                                              Coenzyme Q (CoQ) is an isoprenylated quinone that is ess
109      Previously we showed that deficiency of coenzyme Q (CoQ) is necessary and sufficient for IR in a
110                                              Coenzyme Q (CoQ) is produced in the inner membrane of mi
111                                              Coenzyme Q (CoQ) is utilized as the oxidant.
112                                              Coenzyme Q (CoQ) lipids are ancient electron carriers th
113 ality because its concentration reflects the coenzyme Q (CoQ) pool redox state, a central redox coupl
114 man PDAC cell lines require this pathway for coenzyme Q (CoQ) synthesis and redox homeostasis.
115 on elongation factor TIF1y directly controls coenzyme Q (CoQ) synthesis gene expression.
116        Here we show that in obesity, hepatic coenzyme Q (CoQ) synthesis is impaired, which increases
117 erated) have a programmed deficit in cardiac coenzyme Q (CoQ) that was associated with accelerated ca
118                                              Coenzyme Q (CoQ), a redox-active lipid essential for oxi
119 ring flavoprotein that shuttles electrons to coenzyme Q (CoQ).
120                                              Coenzyme Q (CoQ, ubiquinone) is an essential cellular co
121 ond its role in mitochondrial bioenergetics, Coenzyme Q (CoQ, ubiquinone) serves as a key membrane-em
122 erting lanostane to ergostane triterpenoids, coenzymes Q (COQ) for antroquinonol biosynthesis in myce
123 d ADI), NADPH/NADP(+) and/or reduced form of coenzyme Q (CoQH(2))/CoQ redox potentials (NDI1, AOX, Lb
124 in (ETC)-through complex I/II or directly to coenzyme Q/cytochrome c.
125  the mevalonate-cholesterol pathway, such as coenzyme Q, driven by increased activity of the transcri
126  mouse heart mitochondria, a model system of coenzyme Q excess and relatively decreased mPTP open pro
127                          The biosynthesis of coenzyme Q from pABA requires a deamination reaction at
128  deletion in COQ7 leading to a deficiency in coenzyme Q had a much more severe thermosensitivity phen
129                                We found that coenzyme Q had no effect on the fatty acid-dependent pro
130 ynthesis of sterols, carotenoids, dolichols, coenzyme Q, heme a and farnesylated proteins.
131                            We measured serum coenzyme Q in 1,191 patients with ischemic systolic hear
132               The isoprenylated benzoquinone coenzyme Q is a redox-active lipid essential for electro
133 rpose of this study was to determine whether coenzyme Q is an independent predictor of prognosis in h
134                             We conclude that coenzyme Q is not a cofactor of UCP-mediated proton tran
135                                              Coenzyme Q is not an independent prognostic variable in
136                                  Ubiquinone (coenzyme Q) is a lipid that transports electrons in the
137                    Ubiquinone (also known as coenzyme Q) is a ubiquitous lipid-soluble redox cofactor
138                                  Ubiquinone (Coenzyme Q) is a vital respiratory cofactor and liposolu
139                                  Ubiquinone (coenzyme Q) is the generic name of a class of lipid-solu
140         Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both
141 al inner membrane feeding electrons into the coenzyme Q-junction.
142 ATP), increased oxidative stress, suppressed coenzyme Q levels, and hemoprotein dysregulation.
143 th the terminal stages of CI assembly and in coenzyme Q metabolism, and that pathogenic RTN4IP1 varia
144 es the electrons one at a time from FMN to a coenzyme Q molecule bound in the vicinity of the junctio
145 a substrate of the CYP2U1 enzyme, as well as coenzyme Q, neopterin, and IFN-a levels as putative biom
146               We also examined the effect of coenzyme Q on fatty acid-catalyzed proton flux in liposo
147                                  Ubiquinone (coenzyme Q or Q) is a lipid that functions in the electr
148                                  Ubiquinone (coenzyme Q or Q) is a lipophilic metabolite that functio
149                                  Ubiquinone (coenzyme Q or Q) is an essential component of the mitoch
150 siae homologue, is essential for ubiquinone (coenzyme Q or Q) synthesis and therefore respiration.
151    RQ is structurally similar to ubiquinone (coenzyme Q or Q), a polyprenylated benzoquinone used in
152 d in the biosynthetic pathway of ubiquinone (coenzyme Q or UQ).
153 s in the biosynthetic pathway of ubiquinone (coenzyme Q, or Q).
154 sess the retinal consequences of stimulating coenzyme Q oxidation and respiration without ATP generat
155 es the importance to outer retinal health of coenzyme Q oxidation in the RPE and identifies a metabol
156                                  Ubiquinone (Coenzyme Q) plays an important role in the mitochondrial
157 inates from a depletion of the mitochondrial coenzyme Q pool.
158                          The biosynthesis of coenzyme Q presents a paradigm for how cells surmount hy
159                                              Coenzyme Q (Q (n) ) is a vital lipid component of the el
160                                              Coenzyme Q (Q or ubiquinone) is a redox active lipid com
161             Here, we show that withdrawal of coenzyme Q (Q) from the diet of wild-type nematodes exte
162                                              Coenzyme Q (Q) functions in the electron transport chain
163                                              Coenzyme Q (Q) is a lipid that functions as an electron
164                                              Coenzyme Q (Q) is a redox active lipid essential for aer
165                                              Coenzyme Q (Q) is an essential component of the mitochon
166 lfide clearance, coupling H(2)S oxidation to coenzyme Q reduction.
167  Q, but even in patients with a low baseline coenzyme Q, rosuvastatin treatment was not associated wi
168 tients in the lowest compared to the highest coenzyme Q tertile in a univariate analysis (hazard rati
169                       Enforcing synthesis of coenzyme Q through deletion of Fdft1 or overexpression o
170         Most of the Coq proteins involved in coenzyme Q (ubiquinone or Q) biosynthesis are interdepen
171                                              Coenzyme Q (ubiquinone or Q) functions in the respirator
172                                              Coenzyme Q (ubiquinone or Q) is a crucial mitochondrial
173                                              Coenzyme Q (ubiquinone or Q) is a redox-active lipid fou
174                                              Coenzyme Q (ubiquinone or Q) is an essential lipid compo
175                                              Coenzyme Q (ubiquinone or Q) plays a well known electron
176 n which the intra-mitochondrial synthesis of coenzyme Q (ubiquinone, Q) and Q levels are profoundly d
177  a triphenylphosphonium-conjugated analog of coenzyme Q, using a rat model.
178 S to a persulfide and transfers electrons to coenzyme Q via a flavin cofactor.
179                                              Coenzyme Q was not an independent predictor of any other
180  such as COQ3, required for the synthesis of coenzyme Q, were reduced in their ability to accumulate

 
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